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At least 1,441 records · Page 80

Johnson Space Center's regenerative life support systems test bed

The Regenerative Life Support System (RLSS) Test Bed at NASA's Johnson Space Center is an atmospherically closed, controlled environment facility for the evaluation of regenerative life support systems using higher plants in conjunction with physicochemical life support systems. When completed, the facility will be comprised of two large scale plant growth chambers, each with approximately 10 m(exp 2) growing area. One of the two chambers, the Variable Pressure Growth Chamber (VPGC), will be capable of operating at lower atmospheric pressures to evaluate a range of environments that may be used in Lunar or Martian habitats; the other chamber, the Ambient Pressure Growth Chamber (APGC) will operate at ambient atmospheric pressure. The root zone in each chamber will be configurable for hydroponic or solid state media systems. Research will focus on: (1) in situ resource utilization for CELSS systems, in which simulated lunar soils will be used in selected crop growth studies; (2) integration of biological and physicochemical air and water revitalization systems; (3) effect of atmospheric pressure on system performance; and (4) monitoring and control strategies.

Henninger, Donald L.↗

Review and Analysis of Algorithmic Approaches Developed for Prognostics on CMAPSS Dataset

Benchmarking of prognostic algorithms has been challenging due to limited availability of common datasets suitable for prognostics. In an attempt to alleviate this problem several benchmarking datasets have been collected by NASA's prognostic center of excellence and made available to the Prognostics and Health Management (PHM) community to allow evaluation and comparison of prognostics algorithms. Among those datasets are five C-MAPSS datasets that have been extremely popular due to their unique characteristics making them suitable for prognostics. The C-MAPSS datasets pose several challenges that have been tackled by different methods in the PHM literature. In particular, management of high variability due to sensor noise, effects of operating conditions, and presence of multiple simultaneous fault modes are some factors that have great impact on the generalization capabilities of prognostics algorithms. More than 70 publications have used the C-MAPSS datasets for developing data-driven prognostic algorithms. The C-MAPSS datasets are also shown to be well-suited for development of new machine learning and pattern recognition tools for several key preprocessing steps such as feature extraction and selection, failure mode assessment, operating conditions assessment, health status estimation, uncertainty management, and prognostics performance evaluation. This paper summarizes a comprehensive literature review of publications using C-MAPSS datasets and provides guidelines and references to further usage of these datasets in a manner that allows clear and consistent comparison between different approaches.

Uncertainty↗

Zoledronate Prevents Simulated Weightlessness-Induced Bone Loss in the Cancellous Compartment While Blunting the Efficacy of a Mechanical Loading Countermeasure

Astronauts using high-force resistance training while weightless show a high-turnover remodeling state within the skeletal system, with resorption and formation biomarkers being elevated. One countermeasure for the skeletal health of astronauts includes an antiresorptive of the bisphosphonate (BP) drug class. We asked, does the combination of an anti-resorptive and high-force exercise during weightlessness have negative effects on bone remodeling and strength? In this study, we developed an integrated model to mimic the mechanical strain of exercise via cyclical loading (CL) in mice treated with the BP Zoledronate (ZOL) combined with hind limb unloading (HU) to simulate weightlessness. We hypothesized that ZOL prevents structural degradation from simulated weightlessness and that CL and ZOL interact to render CL less effective. Thirty-two C57BL/6 mice (male, 16 weeks old, n=8/group) were exposed to 3 weeks of either HU or normal ambulation (NA). Cohorts of mice received one subcutaneous injection of ZOL (45μg/kg), or saline vehicle (VEH), prior to the start of HU. The right tibia was axially compressed in vivo 60x/day to 9N (+1200μstrain on the periosteal surface) and repeated 3x/week during HU. Left tibiae served as a within subject, non-compressed control. Ex vivo μCT was performed on all subjects to determine cancellous and cortical architectural parameters. Static and dynamic histomorphometry were carried out for the left and right tibiae to determine osteoclast- and osteoblast relevant surfaces. Further, micro damage was assessed in select groups by basic-fuchsin staining to test whether CL had an effect. For all assays, a multivariate (2x2x2) ANCOVA model was used to account for body weight changes. Additionally, for the tibiae, we incorporated a random effect for the subject (hence, a mixed model) to account for observations of both left and right tibiae within each subject. P < 0.05 was considered significant. In the cancellous compartment of the proximal tibial metaphysis, we observed a main effect from each independent variable, as determined by structural and histomorphometric assays. Specifically, as expected, ZOL showed an increase in the cancellous bone volume to total volume fraction (BV/TV, +32%) and trabecular number (+18%) compared to the VEH. As expected, ZOL decreased osteoclast surface (OC/BS) by -45% compared to VEH. Surprisingly, ZOL reduced mineralizing surface (MS/BS) and bone formation rate (BFR), indicators of osteoblast activity, by -40% and -54%, respectively, compared to VEH. Altogether, ZOL-treated mice displayed a low turnover state of remodeling in the metaphysis. In the context of skeletal aging, we speculate that ZOL prevented age-related cancellous strut loss during the experiment. As a main effect, as expected, HU decreased BV/TV by - 31% via reductions in both trabecular thickness (-11%) and number (-22%) compared to NA controls. Additionally, HU decreased MS/BS by -38% and bone formation rate (BFR) by -50% compared to NA controls. Altogether, these data are consistent with structural degradation resulting from imbalanced remodeling that favors resorption. As a main effect, CL increased BV/TV by +15% via increased trabecular thickness (+12%) compared to the noncompressed limb. As expected, CL increased MS/BS (+20%) and BFR (+24%), indicating osteoblast mineralization contributed to bone gains. These data show that CL provided an anabolic stimulus to the cancellous tissue. We observed unique interactions in ZOL*CL and HU*CL. First, ZOL prevented CL-induced increases in BV/TV and trabecular number, as compared to VEH. In the context of skeletal aging, these data suggest no added benefit from CL in the ZOL-treated mice. Interestingly, no microdamage was observed in mice that were unloaded and treated with ZOL (independent of CL). Secondly, HU prevented CL-induced increases in BFR, as compared to NA controls. These data suggest that either exercise is less effective or the kinetics of formation are slower during simulated weightlessness. Osteoclast surface was unchanged by either treatment. Thus, in contrast to exercising astronauts, these data do not suggest a high-turnover state in the metaphysis. To assess mechanical properties as a function of HU or ZOL, we tested the left femur in three-point bending ex vivo. As expected, HU decreased stiffness (-30%) compared to NA, and ZOL increased stiffness compared to VEH (+28%). Interestingly, HU increased the post-yield displacement, related to collagenous tensile loading, compared to NA (+20%). ZOL increased yield force (+11%) and ultimate force (+17%), which seems to explain the significant effect of ZOL increasing total energy (work-to-fracture, +15%), while not affecting the post yield displacement. Taken together, ZOL did not have detrimental affect on mechanical properties. Our integrated model simulates the combination of weightlessness, exercise-induced mechanical strain, and anti-resorptive treatment that astronauts experience during space missions. We conclude that Zoledronate was an effective countermeasure against weightlessness-induced bone loss, though zoledronate, as well as weightlessness, rendered exercise-related mechanical loading less effective.

bone↗

Neuroimmune responses to space radiation

One of the main health risks in human deep space exploration is central nervous system (CNS) damage by ionizing radiation due to exposure to galactic cosmic rays (GCRs). In animal models, irradiation with simulated GCRs or their components has been shown to cause neurodegeneration and neuroinflammation associated with cognitive and behavioral dysfunction. The extent of CNS damage is partially mediated by the blood-brain barrier (BBB), which regulates the interaction between CNS and systemic responses to stressors in the rest of the body. The main cellular regulators of BBB permeability are astrocytes, which also modulate neuronal death, neuroinflammation and oxidative stress. However, studies on BBB and astrocyte functions in regulating CNS responses to ionizing radiation have been limited, especially in human tissue/organ analogs. Therefore, we developed a high-throughput 3D organ-on-a-chip system to study human CNS and BBB impairments caused by deep space radiation. We investigated both immediate and delayed CNS responses to major GCR components: 0.3-0.8Gy 600MeV/n 56Fe ions; as well as to 0.5-1Gy X-rays. We observed ionizing radiation-mediated increases in BBB permeability that was exacerbated by astrocyte presence and accompanied by damage to endothelial cells and tight junctions, altered cytokine expression including TNFalpha upregulation, and increased oxidative stress. In particular, 600MeV/n 56Fe particle irradiation selectively induced astrocyte damage and increased blood-brain barrier permeability only in models that contained astrocytes in addition to endothelial cells, indicating astrocytes as a particularly radiosensitive component of the CNS that could therefore be a suitable a target for neuroprotection. Future studies will compare human and mouse CNS model responses to simulated GCRs and evaluate the induction of an anti-inflammatory phenotype in astrocytes as a potential countermeasure. Furthermore, in our lab we have been exploring the individual variability, genomic associations and secreted biomarkers of responses to space radiation, which could eventually be combined to address personalized CNS health risk and develop individual countermeasures. Ultimately, we aim to expand upon these results to uncover novel cellular and mechanistic targets for countermeasure development to mitigate human CNS damage in deep space exploration.

space radiation↗

Aeroelastic Trim Drag Optimization of Mach 0.745 Transonic Truss-Braced Wing Aircraft with Variable-Camber Continuous Trailing-Edge Flap

This paper presents an aeroelastic trim drag optimization study of the Mach 0.745 Transonic Truss-Braced Wing (TTBW) aircraft with the Variable-Camber Continuous Trailing-Edge Flap (VCCTEF). An aero-structural analysis solver VSPAERO with transonic small disturbance, integral boundary-layer, and wing-strut interference corrections coupled to finite-element code BEAM3D is developed to provide a rapid aircraft aeroelastic performance evaluation. The VSPAERO model has been validated against wind tunnel test data. Aeroelastic trim drag optimization studies are conducted for a VCCTEF configuration with 6-spanwise sections. Three different flight conditions corresponding to Mach 0.745 are selected for the TTBW aircraft aeroelastic trim drag optimization at the design and off-design cruise lift coefficients. The preliminary optimization results show that the TTBW aircraft with the optimized VCCTEF deflection achieves a drag reduction of about 9.1 counts, 5.9 counts, and 11.8 counts corresponding to the lift coefficients 0.68, 0.73, and 0.78, respectively. A high-fidelity CFD solver FUN3D is used to validate the aeroelastic trim drag optimization.

Aeroelastic trim drag↗

Ultraviolet observations of selected astronomical sources

The results of the 9th and 10th IUE episode programs listed are summarized. Observations and basic data reductions were completed for 4 extragalactic programs which were allocated a total of 9 US1 shifts, and 2 stellar investigations which used 10 US2 shifts. Use was made of the Goddard RDAF to obtain better signal to noise ratio spectra using the Gaussian extraction routines. Highlights include the first IUE observations of H1821+643, the second brightest quasar in the sky, and the discovery of accretion disk emission line profiles in the elliptical Seyfert galaxy Arp 102B. Both of these observations were accompanied by nearly simultaneous optical spectrophotometry. As a result of the stellar programs, large amplitude variability associated with the rotation period of the Ap stars 78 Vir and 53 Cam was found.

Halpern, Jules P.↗

Arctic Stratus Cloud Properties and Their Effect on the Surface Radiation Budget: Selected Cases from FIRE ACE

To study Arctic stratus cloud properties and their effect on the surface radiation balance during the spring transition season, analyses are performed using data taken during three cloudy and two clear days in May 1998 as part of the First ISCCP Regional Experiment (FIRE) Arctic Cloud Experiment (ACE). Radiative transfer models are used in conjunction with surface- and satellite-based measurements to retrieve the layer-averaged microphysical and shortwave radiative properties. The surface-retrieved cloud properties in Cases 1 and 2 agree well with the in situ and satellite retrievals. Discrepancies in Case 3 are due to spatial mismatches between the aircraft and the surface measurements in a highly variable cloud field. Also, the vertical structure in the cloud layer is not fully characterized by the aircraft measurements. Satellite data are critical for understanding some of the observed discrepancies. The satellite-derived particle sizes agree well with the coincident surface retrievals and with the aircraft data when they were collocated. Optical depths derived from visible-channel data over snow backgrounds were overestimated in all three cases, suggesting that methods currently used in satellite cloud climatologies derive optical depths that are too large. Use of a near-infrared channel with a solar infrared channel to simultaneously derive optical depth and particle size appears to alleviate this overestimation problem. Further study of the optical depth retrieval is needed. The surface-based radiometer data reveal that the Arctic stratus clouds produce a net warming of 20 W m(exp -2) in the surface layer during the transition season suggesting that these clouds may accelerate the spring time melting of the ice pack. This surface warming contrasts with the net cooling at the top of the atmosphere (TOA) during the same period. All analysis of the complete FIRE ACE data sets will be valuable for understanding the role of clouds during the entire melting and refreezing process that occurs annually in the Arctic.

Doug, Xiquan↗

Off-design performance loss model for radial turbines with pivoting, variable-area stators

An off-design performance loss model was developed for variable stator (pivoted vane), radial turbines through analytical modeling and experimental data analysis. Stator loss is determined by a viscous loss model; stator vane end-clearance leakage effects are determined by a clearance flow model. Rotor loss coefficient were obtained by analyzing the experimental data from a turbine rotor previously tested with six stators having throat areas from 20 to 144 percent of design area and were correlated with stator-to-rotor throat area ratio. An incidence loss model was selected to obtain best agreement with experimental results. Predicted turbine performance is compared with experimental results for the design rotor as well as with results for extended and cutback versions of the rotor. Sample calculations were made to show the effects of stator vane end-clearance leakage.

Meitner, P. L.↗

Effects of higher order control systems on aircraft approach and landing longitudinal handling qualities

An investigation of approach and landing longitudinal flying qualities, based on data generated using a variable stability NT-33 aircraft combined with significant control system dynamics is described. An optimum pilot lead time for pitch tracking, flight path angle tracking, and combined pitch and flight path angle tracking tasks is determined from a closed loop simulation using integral squared error (ISE) as a performance measure. Pilot gain and lead time were varied in the closed loop simulation of the pilot and aircraft to obtain the best performance for different control system configurations. The results lead to the selection of an optimum lead time using ISE as a performance criterion. Using this value of optimum lead time, a correlation is then found between pilot rating and performance with changes in the control system and in the aircraft dynamics. It is also shown that pilot rating is closely related to pilot workload which, in turn, is related to the amount of lead which the pilot must generate to obtain satisfactory response. The results also indicate that the pilot may use pitch angle tracking for the approach task and then add flight path angle tracking for the flare and touchdown.

Pasha, M. A.↗

On modeling dilution jet flowfields

This paper compares temperature field measurements from selected experiments on a single row, and opposed rows, of jets injected into a ducted crossflow with profiles calculated using an empirical model based on assumed vertical profile similarity and superposition, and distributions calculated with a 3-D elliptic code using a standard K-E turbulence model. The empirical model predictions are very good within the range of the generating experiments, and the numerical model resultings, although exhibiting too little mixing, correctly describe the effects of the principal flow and geometric variables.

Holdeman, J. D.↗

On modeling dilution jet flowfields

This paper compares temperature field measurements from selected experiments on a single row, and opposed rows, of jets injected into a ducted crossflow with profiles calculated using an empirical model based on assumed vertical profile similarity and superposition, and distributions calculated with a 3-D elliptic code using a standard K-E turbulence model. The empirical model predictions are very good within the range of the generating experiments, and the numerical model results, although exhibiting too little mixing, correctly describe the effects of the principal flow and geometric variables.

Holdeman, J. D.↗

SeaWiFS technical report series. Volume 32: Level-3 SeaWiFS data products. Spatial and temporal binning algorithms

The level-3 data products from the Sea-viewing Wide Field-of-view Sensor (SeaWiFS) are statistical data sets derived from level-2 data. Each data set will be based on a fixed global grid of equal-area bins that are approximately 9 x 9 sq km. Statistics available for each bin include the sum and sum of squares of the natural logarithm of derived level-2 geophysical variables where sums are accumulated over a binning period. Operationally, products with binning periods of 1 day, 8 days, 1 month, and 1 year will be produced and archived. From these accumulated values and for each bin, estimates of the mean, standard deviation, median, and mode may be derived for each geophysical variable. This report contains two major parts: the first (Section 2) is intended as a users' guide for level-3 SeaWiFS data products. It contains an overview of level-0 to level-3 data processing, a discussion of important statistical considerations when using level-3 data, and details of how to use the level-3 data. The second part (Section 3) presents a comparative statistical study of several binning algorithms based on CZCS and moored fluorometer data. The operational binning algorithms were selected based on the results of this study.

Hooker, Stanford B.↗

Ultrasensitive Human Radiation Dosimetry

The problem we are addressing concerns the astronauts, and their exposure to radiation during spaceflight. The amount of this radiation is a variable depending on solar events and orbital characteristics. Our goal is to measure the total integrated quantity of radiation damage to the cell nucleus in astronauts or other people exposed to radiation. In my lab, we are turning up the microscope from the level of the chromosome, about eight orders of magnitude, to the molecular level. It is well known that radiation causes DNA and chromosome damage. We are developing methods to measure a specific molecular lesion. The lesion that we have selected to measure is thymidine diol, which is created by hydroxyl radicals adding across the 5.6 double bond of thymidine in DNA.

Hammen, Richard↗

Neighboring Optimal Aircraft Guidance in a General Wind Environment

Method and system for determining an optimal route for an aircraft moving between first and second waypoints in a general wind environment. A selected first wind environment is analyzed for which a nominal solution can be determined. A second wind environment is then incorporated; and a neighboring optimal control (NOC) analysis is performed to estimate an optimal route for the second wind environment. In particular examples with flight distances of 2500 and 6000 nautical miles in the presence of constant or piecewise linearly varying winds, the difference in flight time between a nominal solution and an optimal solution is 3.4 to 5 percent. Constant or variable winds and aircraft speeds can be used. Updated second wind environment information can be provided and used to obtain an updated optimal route.

Jardin, Matthew R.↗

Estimating Surface Soil Moisture in Simulated AVIRIS Spectra

Soil albedo is influenced by many physical and chemical constituents, with moisture being the most influential on the spectra general shape and albedo (Stoner and Baumgardner, 1981). Without moisture, the intrinsic or matrix reflectance of dissimilar soils varies widely due to differences in surface roughness, particle and aggregate sizes, mineral types, including salts, and organic matter contents. The influence of moisture on soil reflectance can be isolated by comparing similar soils in a study of the effects that small differences in moisture content have on reflectance. However, without prior knowledge of the soil physical and chemical constituents within every pixel, it is nearly impossible to accurately attribute the reflectance variability in an image to moisture or to differences in the physical and chemical constituents in the soil. The effect of moisture on the spectra must be eliminated to use hyperspectral imagery for determining minerals and organic matter abundances of bare agricultural soils. Accurate soil mineral and organic matter abundance maps from air- and space-borne imagery can improve GIS models for precision farming prescription, and managing irrigation and salinity. Better models of soil moisture and reflectance will also improve the selection of soil endmembers for spectral mixture analysis.

Whiting, Michael L.↗

Land Surface Phenology from MODIS: Characterization of the Collection 5 Global Land Cover Dynamics Product

Information related to land surface phenology is important for a variety of applications. For example, phenology is widely used as a diagnostic of ecosystem response to global change. In addition, phenology influences seasonal scale fluxes of water, energy, and carbon between the land surface and atmosphere. Increasingly, the importance of phenology for studies of habitat and biodiversity is also being recognized. While many data sets related to plant phenology have been collected at specific sites or in networks focused on individual plants or plant species, remote sensing provides the only way to observe and monitor phenology over large scales and at regular intervals. The MODIS Global Land Cover Dynamics Product was developed to support investigations that require regional to global scale information related to spatiotemporal dynamics in land surface phenology. Here we describe the Collection 5 version of this product, which represents a substantial refinement relative to the Collection 4 product. This new version provides information related to land surface phenology at higher spatial resolution than Collection 4 (500-m vs. 1-km), and is based on 8-day instead of 16-day input data. The paper presents a brief overview of the algorithm, followed by an assessment of the product. To this end, we present (1) a comparison of results from Collection 5 versus Collection 4 for selected MODIS tiles that span a range of climate and ecological conditions, (2) a characterization of interannual variation in Collections 4 and 5 data for North America from 2001 to 2006, and (3) a comparison of Collection 5 results against ground observations for two forest sites in the northeastern United States. Results show that the Collection 5 product is qualitatively similar to Collection 4. However, Collection 5 has fewer missing values outside of regions with persistent cloud cover and atmospheric aerosols. Interannual variability in Collection 5 is consistent with expected ranges of variance suggesting that the algorithm is reliable and robust, except in the tropics where some systematic differences are observed. Finally, comparisons with ground data suggest that the algorithm is performing well, but that end of season metrics associated with vegetation senescence and dormancy have higher uncertainties than start of season metrics.

Land cover dynamics↗

Characterization of OCO-2 and ACOS-GOSAT biases and errors for flux estimates

We characterize the magnitude of seasonally and spatially varying biases in the National Aeronautics and Space Administration (NASA) Orbiting Carbon Observatory-2 (OCO-2) Version 8 (v8) and the Atmospheric CO2 Observations from Space (ACOS) Greenhouse Gas Observing SATellite (GOSAT) version 7.3 (v7.3) satellite CO2 retrievals by comparisons to measurements collected by the Total Carbon Column Observing Network (TCCON), Atmospheric Tomography (ATom) experiment, and National Oceanic and Atmospheric Administration (NOAA) Earth System Research Laboratory (ESRL) and U. S. Department of Energy (DOE) aircraft, and surface stations. Although the ACOS-GOSAT estimates of the column averaged carbon dioxide (CO2) dry air mole fraction (XCO2) have larger random errors than the OCO-2 XCO2 estimates, and the space-based estimates over land have larger random errors than those over ocean, the systematic errors are similar across both satellites and surface types, 0.6 ± 0.1 ppm. We find similar estimates of systematic error whether dynamic versus geometric coincidences or ESRL/DOE aircraft versus TCCON are used for validation (over land), once validation and co-location errors are accounted for. We also find that areas with sparse throughput of good quality data (due to quality flags and preprocessor selection) over land have ~double the error of regions of high-throughput of good quality data. We characterize both raw and bias-corrected results, finding that bias correction improves systematic errors by a factor of 2 for land observations and improves errors by ~0.2 ppm for ocean. We validate the lowermost tropospheric (LMT) product for OCO-2 and ACOS-GOSAT by comparison to aircraft and surface sites, finding systematic errors of ~1.1 ppm, while having 2-3 times the variability of XCO2. We characterize the time and distance scales of correlations for OCO-2 XCO2 errors, and find error correlations on scales of 0.3 degrees, 5-10 degrees, and 60 days. We find comparable scale lengths for the bias correction term. Assimilation of the OCO-2 bias correction term is used to estimate flux errors resulting from OCO-2 seasonal biases, finding annual flux errors on the order of 0.3 and 0.4 PgC/yr for Transcom-3 ocean and land regions, respectively.

Susan S Kulawik↗

Photometric studies of light scattering above the lunar terminator from Apollo solar corona photography

Excess brightness is found in 70-mm photographs of the solar corona above the lunar terminator during Apollo 15 and 17. Maximum brightness of this scattered light is determined from calibration of image density. The observed excess brightness displays circular symmetry above the lunar-horizon subsolar point, characteristic of forward diffraction scattering from micron or submicron size (solid) grains, and decays rapidly in intensity with altitude and distance from the lunar terminator. The observed brightness cannot be accounted for by a co-orbiting cloud of spacecraft contaminants, but requires a variable lunar dust 'atmosphere' over the terminator regions extending to altitudes in excess of 100 km. To maintain such large masses of lunar fines above the terminator requires either local mass-churning rates in excess of 2 by 10 to the -11th power g/sq cm sec or the assumption of some degree of high-altitude electrostatic suspension to increase the dwell time of individual grains at the altitudes observed. Such a model would reduce mass-churning rates while causing selective erosion/deposition and potential for escape of significant mass from the moon

Mccoy, J. E.↗