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Search indexed NASA NTRS and DOE OSTI research on propulsion, heat transfer, battery materials and energy systems. Follow report and document links to the original sources.
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GeneLab Data Processing team members will present the GeneLab standard processing pipelines and RNAseq batch correction project to Analysis Working Group members during the private session of the 2021 AWG Workshop.
For decades, a leaky pipeline analogy has been used when discussing diversity issues in STEM fields. However, this imagery is overly simplistic and does not capture critical issues that contribute to people leaving the field. It puts distance between structural issues, our actions, and why people leave the field. When we view our research structure as something more complex, we can start taking ownership and frame more impactful solutions instead of misidentifying important issues and providing ineffective short-term solutions. Many of the issues discussed in the "Cultivating a culture of inclusivity in Heliophysics" position paper have counterparts within our policies and our institutions. To fully address and mitigate the current issues within our field, we have identified a need to cultivate a positive, safe, inclusive, and effective environment. However, we need both cultural and programmatic changes. We will try to identify systemic issues that inhibit many from fully participating and potential solutions, as well as groups and fields producing best practices for creating and enabling effective environments where innovation can occur.
Microorganisms hold great promise for on demand production of labile nutrients and pharmaceuticals as well recycling and in situ resource utilization. The utilization of microorganisms for such tasks on space missions is hindered by the limited data on how microbes respond to spaceflight. For example, the genetic stability of microorganisms, and the genomic engineered traits added to deliver desired functions, over long-term storage in the spacecraft environment is poorly understood. The BioNutrients-1 (BN-1) mission conducted a 5-year study of desiccated storage in Low Earth Orbit (LEO) to evaluate the suitability of eight synthetic biology chassis organisms for long-duration space missions. We are employing high-depth, whole genome sequencing (WGS) to determine the mutagenic load that accumulated during long-term storage. Mutation analysis pipelines are well established for homogenous culture grown from a single colony, but the mutational landscape of the BN-1 samples present a unique analysis challenge, as every cell in the BN-1 samples had a unique genetic journey of DNA damage and repair. Consequently, sequence variants are expected at low allele frequency within samples. To address this genetic complexity, we apply two distinct computational approaches to identify mutations in pre-existing WGS data collected from populations of Chlamydomonas reinhardtii that were exposed to UV mutagenesis and growth in LEO. For reference genome free mutation detection, we utilized DiscoSNP++, which is a de Bruijn graph approach. For reference genome-based mutation detection we utilize GATK for Microbes, which is a Bayesian probabilistic approach. We will benchmark these approaches against the mutations originally identified using CRISP, a method optimized for pooled samples. Ultimately, quantifying the mutation load imposed by storage or growth on the ISS will help identify chassis organisms with both high levels of genome stability and viability, which are desirable traits for implementation of bioproduction in long-duration missions.
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TESS (Transiting Exoplanet Survey Satellite) launched on 18-4-2018 to conduct a two-year, near all-sky survey for at least 50 nearby exoplanets for which masses can be obtained. TESS just completed surveying the southern hemisphere, identifying hundreds of candidate exoplanet systems and unveiling a plethora of exciting non-exoplanet astrophysics results, such as asteroseismology, asteroids, and supernova. The TESS Science Processing Operations Center (SPOC) at NASA Ames Research Center processes the image data downlinked from TESS every two weeks to generate a variety of data products hosted at the Mikulski Archive for Space Telescopes (MAST). For each approximately 1-month sector, the SPOC calibrates the image data for both 30-minute Full Frame Images (FFIs) and up to 20,000 pre-selected 2-minute target star postage stamps. Simple aperture photometry and systematic error-corrected flux-time series are generated for the 2-minute data. The data products also include co-trending basis vectors (CBVs) and calibration files, such as the Pixel Response Functions (PRF). The archival files are modeled after Kepler's for ease of use, and include Target Pixel Files (TPFs) containing original and calibrated 2-minute image data, Light Curve files (LCs) containing the photometric time series for each 2-minute target, as well as the Data Validation products. New products derived from the FFIs include light curves for the 2-minute targets and CBVs. The TESS Mission is funded by NASA's Science Mission Directorate as an Astrophysics Explorer Mission.
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Joint absorbs all significant torque, is as rugged as heavy metallic pipe, and has thermal insulation comparable to length of flexible pipe. Design is adaptable to any pipes transporting gases or liquids, including those which are noxious or corrosive.
After ten years of evolution, the technology utilization program now uses three basic and complementary technology transfer mechanisms: publication, technical assistance dissemination, and application demonstrations. The marketing of NASA technology and industrial applications is discussed.
3 x 3 convolver produces weighted sum of nine contiguous picture elements in square. Data processed through convolver at video scanning rate of current raster line. Two previous lines stored in external buffers (N-3)element delays. Specific choice of convolution weights determines whether convolver performs smoothing, spatial-frequency filtering, edge detection, or other forms of image processing.
A 3-by-3 convolver utilizes 9 binary arithmetic units connected in cascade for multiplying 12-bit binary pixel values P sub i which are positive or two's complement binary numbers by 5-bit magnitide (plus sign) weights W sub i which may be positive or negative. The weights are stored in registers including the sign bits. For a negative weight, the one's complement of the pixel value to be multiplied is formed at each unit by a bank of 17 exclusive or gates G sub i under control of the sign of the corresponding weight W sub i, and a correction is made by adding the sum of the absolute values of all the negative weights for each 3-by-3 kernel. Since this correction value remains constant as long as the weights are constant, it can be precomputed and stored in a register as a value to be added to the product PW of the first arithmetic unit.
The sensory processing system for the NASA/NBS Standard Reference Model (NASREM) for telerobotic control is described. This control system architecture was adopted by NASA of the Flight Telerobotic Servicer. The control system is hierarchically designed and consists of three parallel systems: task decomposition, world modeling, and sensory processing. The Sensory Processing System is examined, and in particular the image processing hardware and software used to extract features at low levels of sensory processing for tasks representative of those envisioned for the Space Station such as assembly and maintenance are described.
Modification of decoding algorithms leads to simplified conceptual designs for time- and transform-domain Reed-Soloman (RS) decoders suitable for implementation as very-large-scale integrated (VLSI) circuits. New conceptual decoders determine simultaneously errata-locator and errata-evaluator polynomials as part of simplified scheme for corrections of errors and erasures in RS codes. Highly suitable for implementation in both VLSI circuitry and in software on general-purpose computer.
Analysis of a robot control system leads to a broad range of processing requirements. One fundamental requirement of a robot control system is the necessity of a microcomputer system in order to provide sufficient processing capability.The use of multiple processors in a parallel architecture is beneficial for a number of reasons, including better cost performance, modular growth, increased reliability through replication, and flexibility for testing alternate control strategies via different partitioning. A survey of the progression from low level control synchronizing primitives to higher level communication tools is presented. The system communication and control mechanisms of existing robot control systems are compared to the hierarchical control model. The impact of this design methodology on the current robot control systems is explored.
This paper reports and analyzes methane flux measurements made during the summer of 1987 at 10 km intervals along a north-south direction from Prudhoe Bay to the Arctic Circle in Alaska. Mean CH4 flux from the arctic tundra was 52 mg/sq m/d while that from high-latitude taiga was 11 mg/sq m/d. Fluxes in mg/sq m/d for various plant communities were: wet tundra, 90; low brush-muskeg bog, 45; moist tundra, 31; freshwater ponds, 21; spruce forest, 4.6; and alpine tundra, 0.6. Annual CH4 emission from global tundra and taiga environments is estimated at 38 Tg and 15 Tg, respectively. This is about 46 percent of the wetland emission term of 10 percent of the global atmospheric input.