Film Grain Simulation for Oscilloscope Trace Image Synthesis
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Digital rock physics is an often-mentioned approach to better understand and model transport processes occurring in tight nanoporous media including the organic and inorganic matrix of shale. Workflows integrating nanometer-scale image data and pore-scale simulations are relatively undeveloped, however. In this paper, a workflow is demonstrated progressing from sample acquisition and preparation, to image acquisition by Scanning Transmission Electron Microscopy (STEM) tomography, to volumetric reconstruction to pore-space discretization to numerical simulation of pore-scale transport. Key aspects of the workflow include (i) STEM tomography in high angle annular dark field (HAADF) mode to image three-dimensional pore networks in µm-sized samples with nanometer resolution and (ii) lattice Boltzmann method (LBM) simulations to describe gas flow in slip, transitional, and Knudsen diffusion regimes. It is shown that STEM tomography with nanoscale resolution yields excellent representation of the size and connectivity of organic nanopore networks. In turn, pore-scale simulation on such networks contributes to understanding of transport and storage properties of nanoporous shale. Interestingly, flow occurs primarily along pore networks with pore dimensions on the order of tens of nanometers. Smaller pores do not form percolating pathways in the sample volume imaged. Apparent gas permeability in the range of 10−19 to 10−16 m2 is computed.
The newly available ns-gated laser-entrance-hole (LEH) imager on the National Ignition Facility provides routine, non-perturbative measurements of the x-ray emission from laser-heated plasmas inside the hohlraum as viewed at 19° to the hohlraum axis through one of its LEHs. Multiple images are acquired for a series of times and filter-selected x-ray energy bands within a single shot. The images provide time dependent data on phenomena including the effective radius of the LEH, the length of the gold-plasma “bubble” evolving off the interior wall surface heated by the outer beams, the evolving radius of the x-ray heated hohlraum wall, and the radius of the ablation front of the fusion capsule. Here, these measurements are explained and illustrated with sample data. These techniques are then applied to understand hohlraum behavior as a function of gas fill. For hohlraums with helium gas fill densities of 0.15 to 0.30 mg/cm 3 , synthetic images computed from simulations agree well with experimental gated LEH images when an inhibited heat transport model [Jones et al., Phys. Plasmas 24, 056312 (2017)] is used. This model can be adjusted to reproduce the expansion rate of the laser-heated plasma bubble in such a way as to improve agreement with the images. At the higher 0.6 mg/cc gas fill, the experimental images show more pronounced 3D features, resulting in slightly less good agreement with the 2D simulations.
The design of fiber-reinforced composite (FRC)-based components for marine energy applications necessitates a fundamental understanding of material properties and the resulting geometry to predict long-term performance. In this work, we present a modeling workflow to predict linear elastic and diffusive bulk properties at the mesoscale for an idealized geometry based on knowledge of fiber and resin properties. A parametric study was performed to identify the key model input parameters that influence bulk properties. Furthermore, we demonstrate how bulk properties can be leveraged in high-fidelity image-based simulations, where imperfections in tow geometry and voids captured during X-ray computed tomography imaging are explicitly represented within the simulation. Bulk properties of interest include moduli, Poisson’s ratios, hygroscopic swelling, diffusivity, and moisture uptake, which are key parameters for characterizing FRC performance within marine environments. Modeling predictions agreed well with experimental data, except for estimating swelling coefficients, likely due to crack accumulation as a function of moisture uptake. The mesoscale modeling workflow ultimately highlights a versatile framework for understanding the influence of material and geometric properties, which can be leveraged to rapidly assess new FRC-based components.
A set of deep neural network models for rheumatoid arthritis (RA) classification using a highway network, a convolutional neural network and a residual network is proposed based on the data of diffuse optical tomography (DOT) utilising near-infrared light, which ensures early diagnosis of pathophysiological changes resulting from inflammation. A numerical model of the finger is used to generate images to overcome the inherent problem of insufficient clinical DOT images available. The proposed deep neural network models are applied to automatically classify simulated DOT images of inflamed and non-inflamed joints and transfer learning is also used to improve the performance of the classification. The results demonstrate that all three deep neural network methods improve the diagnostic accuracy as compared to the widely applied support vector machine (SVM), especially for high inter-subject variability databases. In cases of distinct modelled severity of disease, residual network achieved the highest accuracy (> 99 %), and both of highway and convolutional neural networks reached 99 %, respectively. However, as the severity of the modelled disease is reduced, this accuracy is reduced to 75.2 % for residual networks. The results indicate that transfer learning can improve the performance of deep neural network methods on RA classification from DOT data and highlight their potential as a computer aided tool in DOT diagnostic systems. (paper)
To investigate the impact of reduced injected doses on the quantitative and qualitative assessment of the amyloid PET tracers [ 18 F]flutemetamol and [ 18 F]florbetaben. Cognitively impaired and unimpaired individuals (N = 250, 36% Aβ-positive) were included and injected with [ 18 F]flutemetamol (N = 175) or [ 18 F]florbetaben (N = 75). PET scans were acquired in list-mode (90–110 min post-injection) and reduced-dose images were simulated to generate images of 75, 50, 25, 12.5 and 5% of the original injected dose. Images were reconstructed using vendor-provided reconstruction tools and visually assessed for Aβ-pathology. SUVRs were calculated for a global cortical and three smaller regions using a cerebellar cortex reference tissue, and Centiloid was computed. Absolute and percentage differences in SUVR and CL were calculated between dose levels, and the ability to discriminate between Aβ- and Aβ + scans was evaluated using ROC analyses. Finally, intra-reader agreement between the reduced dose and 100% images was evaluated. At 5% injected dose, change in SUVR was 3.72% and 3.12%, with absolute change in Centiloid 3.35CL and 4.62CL, for [ 18 F]flutemetamol and [ 18 F]florbetaben, respectively. At 12.5% injected dose, percentage change in SUVR and absolute change in Centiloid were < 1.5%. AUCs for discriminating Aβ- from Aβ + scans were high (AUC ≥ 0.94) across dose levels, and visual assessment showed intra-reader agreement of > 80% for both tracers. This proof-of-concept study showed that for both [ 18 F]flutemetamol and [ 18 F]florbetaben, adequate quantitative and qualitative assessments can be obtained at 12.5% of the original injected dose. However, decisions to reduce the injected dose should be made considering the specific clinical or research circumstances.
Control over colloidal nanocrystal morphology (size, size distribution, and shape) is important for tailoring the functionality of individual nanocrystals and their ensemble behavior. Despite this, traditional methods to quantify nanocrystal morphology are laborious. New developments in automated morphology classification will accelerate these analyses but the assessment of machine learning models is limited by human accuracy for ground truth, causing even unsupervised machine learning models to have inherent bias. Herein, we introduce synthetic image rendering to solve the ground truth problem of nanocrystal morphology classification. By simulating 2D images of nanocrystal shapes via a function of high-dimensional parameter space, we trained a convolutional neural network to link unique morphologies to their simulated parameters, defining nanocrystal morphology quantitatively rather than qualitatively. An automated pipeline then processes, quantitatively defines, and classifies nanocrystal morphology from experimental transmission electron microscopy (TEM) images. Using improved computer vision techniques, 42,650 nanocrystals were identified, assessed, and labeled with quantitative parameters, offering a 600-fold improvement in efficiency over best-practice manual measurements. Further, a classification algorithm was trained with a prediction accuracy of 99.5%, which can successfully analyze a range of concave, convex, and irregular nanocrystal shapes. The resulting pipeline was applied to differentiating two syntheses of nominally cuboidal CsPbBr 3 nanocrystals and uniquely classifying binary nickel sulfide nanocrystal phase based on morphology. This pipeline provides a simple, efficient, and unbiased method to quantify nanocrystal morphology and represents a practical route to construct large datasets with an absolute ground truth for training unbiased morphology-based machine learning algorithms.
Additive manufacturing (AM) is an emerging method for cost-efficient fabrication of complex topology nuclear reactor parts from high-strength corrosion resistance alloys, such as stainless steel and Inconel. AM of metallic structures for nuclear energy applications is currently based on laser powder bed fusion (LPBF) process. Some of the challenges with using LPBF method for nuclear manufacturing include the possibility of introducing pores into metallic structures. Integrity of AM structures needs to be evaluated nondestructively because material flaws could lead to premature failures in high temperature nuclear reactor environment. Currently, there exist limited capabilities to evaluate actual AM structures non-destructively. Pulsed Thermal Tomography Imaging (PTT) provides a capability for non-destructive evaluation (NDE) of subsurface defects in arbitrary size structures. The PTT method is based on recording material surface temperature transients with infrared (IR) camera following thermal pulse delivered on material surface with flash light. The PTT method has advantages for NDE of actual AM structures because the method involves one-sided non-contact measurements and fast processing of large sample areas captured in one image. Following initial qualification of an AM component for deployment in a nuclear reactor, a PTT system can also be used for in-service nondestructive evaluation (NDE) applications. In this report, we describe recent progress in enhancing PTT capabilities in detecting and visualizing microscopic defects in metallic specimens. The thermal tomography (TT) algorithm obtains depth reconstructions of spatial effusivity from the data cube of sequentially recorded surface temperatures. However, interpretation of TT images is non-trivial because of blurring of images with increasing depth. To address this challenge, we have developed a deep learning convolutional neural network (CNN) to classify size and orientation subsurface defects in simulated TT images. CNN is trained on a database of TT images created for a set of simulated metallic structures with elliptical subsurface voids. Test of CNN performance demonstrate the ability to classify radii and angular orientation of subsurface defects in TT images. In addition, we have shown that CNN trained on elliptical defects is capable of classifying irregular-shaped defects obtained from scanning electron microscopy (SEM) of stainless steel sections printed with LPBF.
Ultrafast x-ray and electron scattering techniques have proven to be useful for probing the transient elastic lattice deformations associated with photoexcited coherent acoustic phonons. Indeed, femtosecond electron imaging using an ultrafast electron microscope (UEM) has been used to directly image the influence of nanoscale structural and morphological discontinuities on the emergence, propagation, dispersion, and decay behaviors in a variety of materials. Here, we describe our progress toward the development of methods ultimately aimed at quantifying acoustic-phonon properties from real-space UEM images via conventional image simulation methods extended to the associated strain-wave lattice deformation symmetries and extents. Using a model system consisting of pristine single-crystal Ge and a single, symmetric Lamb-type guided-wave mode, we calculate the transient strain profiles excited in a wedge specimen and then apply both kinematical- and dynamical-scattering methods to simulate the resulting UEM bright-field images. While measurable contrast strengths arising from the phonon wavetrains are found for optimally oriented specimens using both approaches, incorporation of dynamical scattering effects via a multi-slice method returns better qualitative agreement with experimental observations. Contrast strengths arising solely from phonon-induced local lattice deformations are increased by nearly an order of magnitude when incorporating multiple electron scattering effects. We also explicitly demonstrate the effects of changes in global specimen orientation on the observed contrast strength, and we discuss the implications for increasing the sophistication of the model with respect to quantification of phonon properties from UEM images.
Fast analysis of collective Thomson scattering ion acoustic wave features using a deep convolutional neural network model is presented. The network was trained from spectra to predict the plasma parameters, including ion velocities, population fractions, and ion and electron temperatures. A fully kinetic particle-in-cell simulation was used to model a laboratory astrophysics experiment and simulate a diagnostic image of the ion acoustic wave feature. Network predictions were compared with Bayesian inference of the plasma model parameters for both the simulated and experimentally measured images. Both approaches were fairly accurate predicting the simulated image and the network predictions matched a good portion of the Bayesian results for the experimentally measured image. The Bayesian approach is more robust to noise and motivates future work to train deep learning models with realistic noise. The advantage of the deep learning model is making thousands of predictions in a few hundred milliseconds, compared to a few seconds to minutes per prediction for the optimization and Bayesian approaches presented here. The results demonstrate promising capabilities of deep learning models to analyze Thomson data orders of magnitude faster than conventional methods when using the neural network for standalone analysis. If more rigorous analysis is needed, neural network predictions can be used to quickly initialize other optimization methods and increase chances of success. This is especially useful when the dataset becomes very large or highly dimensional and manually refining initial conditions for the entire dataset are no longer tractable.
Abstract Roots are central to the function of natural and agricultural ecosystems by driving plant acquisition of soil resources and influencing the carbon cycle. Root characteristics like length, diameter and volume are critical to measure to understand plant and soil functions. RhizoVision Explorer is an open-source software designed to enable researchers interested in roots by providing an easy-to-use interface, fast image processing and reliable measurements. The default broken roots mode is intended for roots sampled from pots and soil cores, washed and typically scanned on a flatbed scanner, and provides measurements like length, diameter and volume. The optional whole root mode for complete root systems or root crowns provides additional measurements such as angles, root depth and convex hull. Both modes support providing measurements grouped by defined diameter ranges, the inclusion of multiple regions of interest and batch analysis. RhizoVision Explorer was successfully validated against ground truth data using a new copper wire image set. In comparison, the current reference software, the commercial WinRhizo™, drastically underestimated volume when wires of different diameters were in the same image. Additionally, measurements were compared with WinRhizo™ and IJ_Rhizo using a simulated root image set, showing general agreement in software measurements, except for root volume. Finally, scanned root image sets acquired in different labs for the crop, herbaceous and tree species were used to compare results from RhizoVision Explorer with WinRhizo™. The two software showed general agreement, except that WinRhizo™ substantially underestimated root volume relative to RhizoVision Explorer. In the current context of rapidly growing interest in root science, RhizoVision Explorer intends to become a reference software, improve the overall accuracy and replicability of root trait measurements and provide a foundation for collaborative improvement and reliable access to all.
Abstract The X-ray morphologies of clusters of galaxies display significant variations, reflecting their dynamical histories and the nonlinear dependence of X-ray emissivity on the density of the intracluster gas. Qualitative and quantitative assessments of X-ray morphology have long been considered a proxy for determining whether clusters are dynamically active or “relaxed.” Conversely, the use of circularly or elliptically symmetric models for cluster emission can be complicated by the variety of complex features realized in nature, spanning scales from megaparsecs down to the resolution limit of current X-ray observatories. In this work, we use mock X-ray images from simulated clusters from The Three Hundred project to define a basis set of cluster image features. We take advantage of the clusters’ approximate self-similarity to minimize the differences between images before encoding the remaining diversity through a distribution of high-order polynomial coefficients. Principal component analysis then provides an orthogonal basis for this distribution, corresponding to natural perturbations from an average model. This representation allows novel, realistically complex X-ray cluster images to be easily generated, and we provide code to do so. The approach provides a simple way to generate training data for cluster image analysis algorithms and could be straightforwardly adapted to generate clusters displaying specific types of features or selected by physical characteristics available in the original simulations.
Attosecond science has been transforming our understanding of electron dynamics in atoms, molecules, and solids. However, to date almost all of the attoscience experiments have been based on spectroscopic measurements because attosecond pulses have intrinsically very broad spectra due to the uncertainty principle and are incompatible with conventional imaging systems. In this paper we report an important advance towards achieving attosecond coherent diffractive imaging. Using simulated attosecond pulses, we simultaneously reconstruct the spectrum, 17 probes, and 17 spectral images of extended objects from a set of ptychographic diffraction patterns. We further confirm the principle and feasibility of this method by successfully performing a ptychographic coherent diffractive imaging experiment using a light-emitting diode with a broad spectrum. We believe this work clears the way to an unexplored domain of attosecond imaging science, which could have a far-reaching impact across different disciplines.
For the past three years, Oak Ridge National Laboratory (ORNL) has been developing a passive fast-neutron emission tomography capability. The goal of this development is the ability to quantify the neutron source strength of individual fuel pins (rods) in spent nuclear fuel assemblies. Such a system could be used to measure the burnup of each fuel pin in a spent fuel assembly in order to take burnup credit when loading dry storage casks or to count individual fuel pins in spent fuel assemblies for safeguards purposes. At present, a laboratory prototype imager is under construction. The purpose of this prototype is to demonstrate imaging capability sufficient to resolve individual fuel pins in spent fuel assemblies. This report documents the development of the iterative reconstruction code used to perform tomographic image reconstruction, the imager response calculation used by the reconstruction code, and the results of reconstructions of simulated tomographic imaging measurements for the prototype imager design.
Gravitationally lensed supernovae (LSNe) are important probes of cosmic expansion, but they remain rare and difficult to find. Current cosmic surveys likely contain 5–10 LSNe in total while next-generation experiments are expected to contain several hundred to a few thousand of these systems. We search for these systems in observed Dark Energy Survey (DES) five year SN fields—10 3 sq. deg. regions of sky imaged in the griz bands approximately every six nights over five years. To perform the search, we utilize the DeepZipper approach: a multi-branch deep learning architecture trained on image-level simulations of LSNe that simultaneously learns spatial and temporal relationships from time series of images. We find that our method obtains an LSN recall of 61.13% and a false-positive rate of 0.02% on the DES SN field data. DeepZipper selected 2245 candidates from a magnitude-limited (m i < 22.5) catalog of 3,459,186 systems. We employ human visual inspection to review systems selected by the network and find three candidate LSNe in the DES SN fields.
Defects in building envelopes deteriorate over time without being visible to the human eye, while significantly impacting energy performance due to unaccounted heat transfer. Defects can be characterized in the infrared (IR) spectrum. However, IR readings are typically recorded at singular points in time, when in several cases anomalies can only be revealed at specific times of the day, possibly in different seasons of the year. This paper presents a novel workflow for 3D envelope defect characterization and modeling using aerial time-lapse IR data collection using drones. A comprehensive envelope thermal profile is developed for a case study building employing the photogrammetry software Agisoft Photoscan, which generates temporal IR inspections of building skins using multiple thermography orthomosaics. Point-cloud data is then translated into a CAD model and thermal zones for whole Building Energy Modeling (BEM) using Honeybee as a frontend to EnergyPlus to showcase the potential of inclusion of detailed 4D data. Envelope contributions in this case study’s anomalies showed heat losses of 6447.6 kWh, and Energy Use Intensity (EUI) differences of ~2 kWh/m 2 /year from the baseline. Finally, why there is currently little translation of this work in BEM software is discussed, while identifying limitations and future research in the employment of time-lapse thermography using drones for more accurate building envelope inspection and modeling.
X-ray fluorescence (XRF) microscopy is a powerful technique for quantifying the distribution of elements in complex materials, which makes it a crucial imaging technique across a wide range of disciplines in physical and biological sciences, including chemistry, materials science, microbiology, and geosciences. However, as a scanning microscopy technique, the spatial resolution of XRF imaging is inherently constrained by the x-ray probe profile and scanning step size. Here we propose a dual-branch machine learning (ML) model, which can extract scale-variant features and bypass abundant low-frequency information separately, to enhance the spatial resolution of the XRF images by mitigating the effects of blurring from the probe profile. The model is trained by simulated natural images, and a two-stage training strategy is used to overcome the domain gap between the natural images and experimental data. The tomography reconstruction from enhanced XRF projections shows an improvement in resolution by a scale factor of four and reveals distinct internal features invisible in low-resolution XRF within a battery sample. This study offers a promising approach for obtaining high-resolution XRF imaging from its low-resolution version, paving the way for future investigations in a broader range of disciplines and materials.
Cosmic ray muons, originating from interactions in the upper atmosphere, possess high energy and unique penetrative capabilities suitable for non-traditional radiographic inspection. This study explores their application in various fields such as nuclear fuel cask monitoring, nuclear reactor imaging, and archaeology, leveraging the principle of multiple Coulomb scattering for imaging dense materials. While muon scattering tomography has shown promise, accurately measuring muon momentum remains challenging. This research introduces the Momentum Integrated Point-of-Closest Approach (mPoCA) algorithm, integrating muon momentum data into the traditional Point-of-Closest Approach (PoCA) framework. Utilizing the Cherenkov muon spectrometer, renowned for precise muon momentum estimation, the mPoCA algorithm offers a novel imaging approach. Simulations conducted with GEANT4 evaluate the mPoCA algorithm’s performance against the standard PoCA method, demonstrating superior image resolution and enhanced material identification capabilities, particularly in distinguishing materials like uranium and lead. These findings underscore the potential of the mPoCA algorithm for advancing muon scattering tomography applications.