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At least 145 records · Page 8

Simultaneous sample and spatial coherence characterisation using diffractive imaging

We demonstrate an algorithm that reconstructs the complex transmission function of an object from experimental X-ray diffraction data using partially coherent 1.4 keV X-rays that does not require a priori input of the coherence function. The quality of the reconstruction is significantly better than that obtained by assuming that the illumination is fully coherent. Our approach can be readily applied to diffraction imaging problems where a model for the spatial coherence can be assumed.

71 CLASSICAL AND QUANTUM MECHANICS, GENERAL PHYSIC↗

Strain annealing of SiC nanoparticles revealed through Bragg coherent diffraction imaging for quantum technologies

The crystalline strain properties of nanoparticles have broad implications in a number of emerging fields, including quantum and biological sensing in which heterogeneous internal strain fields are detrimental to performance. Here we used synchrotron-based Bragg coherent x-ray diffraction imaging (BCDI) to measure three-dimensional lattice strain fields within individual 3C-SiC nanoparticles, a candidate host material for quantum sensing, as a function of temperature during and after annealing up to 900 degrees C. We observed pronounced homogenization of the initial strain field at temperatures above 500 degrees C, and we find that the surface layers and central volumes of the nanoparticles reduce strain at similar rates, suggesting a uniform healing mechanism. Thus, we attribute the observed strain homogenization to activation of mobile point defects that annihilate and improve the overall quality of the crystal lattice. This work also establishes the feasibility of performing BCDI at high temperatures (up to 900 degrees C) to map structural hystereses relevant to the processing of quantum nanomaterials.

71 CLASSICAL AND QUANTUM MECHANICS, GENERAL PHYSIC↗

Improvement of lateral resolution of spectral domain optical coherence tomography images in out-of-focus regions with holographic data processing techniques

An analogy between spectral-domain optical coherence tomography (SD OCT) data and broadband digital holography data is considered. Based on this analogy, a method for processing SD OCT data, which makes it possible to construct images with a lateral resolution in the whole investigated volume equal to the resolution in the in-focus region, is developed. Several issues concerning practical application of the proposed method are discussed. (laser biophotonics)

46 INSTRUMENTATION RELATED TO NUCLEAR SCIENCE AND ↗

Three-dimensional coherent Bragg imaging of spontaneously rotating nanoparticles

This dataset contains spontaneous rocking curves of individual 60 nm gold particles, measured as CDI patterns in the Bragg geometry. The dataset provides a higher-quality alternative to ID 151, and is collected at lower energy, shorter detector distance (~120 mm) and using a He-filled flight tube. Additionally, this data includes measurements along the (111), (200), and (220) directions, providing access to multiple strain directions.

60 nm truncated-octrahedral gold nanoparticles↗

Development of polarization-sensitive optical coherence tomography imaging platform and metrics to quantify electrostimulation-induced peripheral nerve injury in vivo in a small animal model

Neuromodulation devices are rapidly evolving for the treatment of neurological diseases and conditions. Injury from implantation or long-term use without obvious functional losses is often only detectable through terminal histology. New technologies are needed that assess the peripheral nervous system (PNS) under normal and diseased or injured conditions. We aim to demonstrate an imaging and stimulation platform that can elucidate the biological mechanisms and impacts of neurostimulation in the PNS and apply it to the sciatic nerve to extract imaging metrics indicating electrical overstimulation. A sciatic nerve injury model in a 15-rat cohort was observed using a newly developed imaging and stimulation platform that can detect electrical overstimulation effects with polarization-sensitive optical coherence tomography. The sciatic nerve was electrically stimulated using a custom-developed nerve holder with embedded electrodes for 1 h, followed by a 1-h recovery period, delivered at above-threshold Shannon model k-values in experimental groups: sham control (SC, n = 5, 0.0 mA / 0 Hz), stimulation level 1 (SL1, n = 5, 3.4 mA / 50 Hz, and k = 2.57), and stimulation level 2 (SL2, n = 5, 6.8 mA / 100 Hz, and k = 3.17). The stimulation and imaging system successfully captured study data across the cohort. When compared to a SC after a 1-week recovery, the fascicle closest to the stimulation lead showed an average change of +4 % / – 309 % (SL1/SL2) in phase retardation and –79 % / – 148 % in optical attenuation relative to SC. Analysis of immunohistochemistry (IHC) shows a +1 % / – 36 % difference in myelin pixel counts and –13 % / + 29 % difference in axon pixel counts, and an overall increase in cell nuclei pixel count of +20 % / + 35 % . These metrics were consistent with IHC and hematoxylin/eosin tissue section analysis. The poststimulation changes observed in our study are manifestations of nerve injury and repair, specifically degeneration and angiogenesis. Optical imaging metrics quantify these processes and may help evaluate the safety and efficacy of neuromodulation devices.

60 APPLIED LIFE SCIENCES↗

Design concepts for an on-board coherent optical image processor

On-board spacecraft image data processing systems for transmitting processed data rather than raw data are discussed. A brief history of the development of the optical data processing techniques is presented along with the conceptual design of a coherent optical system with a noncoherent image input.

Husain-Abidi, A. S.↗

Optical coherence tomography imaging of plant root growth in soil

Complex interactions between roots and soil provide the nutrients and physical support required for robust plant growth. Yet, visualizing the root-soil interface is challenged by soil’s opaque scattering characteristics. In this paper, we describe methods for using optical coherence tomography (OCT) to provide non-destructive 3D and cross-sectional root imaging not available with traditional bright field microscopy. OCT is regularly used for bioimaging, especially in ophthalmology where it can detect retinal abnormalities. Prior use of OCT in plant biology has focused on surface defects of above ground tissues, predominantly in food crops. Our results show OCT is also viable for detailed, in situ study of living plant roots.

59 BASIC BIOLOGICAL SCIENCES↗

A new real-time non-coherent to coherent light image converter - The hybrid field effect liquid crystal light valve

A new, high-performance device has been developed for application to real-time coherent optical data processing. The new device embodies a CdS photoconductor, a CdTe light-absorbing layer, a dielectric mirror, and a liquid crystal layer sandwiched between indium-tin-oxide transparent electrodes deposited on optical quality glass flats. The noncoherent image is directed onto the photoconductor; this reduces the impedance of the photoconductor, thereby switching the ac voltage that is impressed across the electrodes onto the liquid crystal to activate the device. The liquid crystal is operated in a hybrid field effect mode. It utilizes the twisted nematic effect to create a dark off-state and the optical birefringence effect to create the bright on-state. The liquid crystal modulates the polarization of the coherent read-out light so an analyzer must be used to create an intensity modulated output beam.

Grinberg, J.↗

Inversion of coherent surface scattering images via deep learning network

Coherent surface scattering imaging is a powerful tool for imaging a surface/interface of a thin nanostructure deposited on an opaque substrate. A mathematical conversion of an object image from a scattering pattern is essential for coherent surface scattering imaging to visualize structures of specimens. It has been achieved by using phase retrieval algorithms requiring oversampling in scattering patterns and employing alternating projection approaches. It is a computationally challenging and time-consuming process. In this paper, we demonstrate CSSI-NN, which is a deep learning neural network model to predict images of objects from scattering intensities in coherent surface scattering imaging. This model allowing for the instant outcome from scattering patterns would be tremendously beneficial not only for effective experiments but also for data analysis of phase retrieval.

71 CLASSICAL AND QUANTUM MECHANICS, GENERAL PHYSIC↗

Automated Segmentation and Quantification of Drusen in Fundus and Optical Coherence Tomography Images for Detection of ARMD

Age-related macular degeneration (ARMD) is one of the most common retinal syndromes that occurs in elderly people. Different eye testing techniques such as fundus photography and optical coherence tomography (OCT) are used to clinically examine the ARMD-affected patients. Many researchers have worked on detecting ARMD from fundus images, few of them also worked on detecting ARMD from OCT images. However, there are only few systems that establish the correspondence between fundus and OCT images to give an accurate prediction of ARMD pathology. In this paper, we present fully automated decision support system that can automatically detect ARMD by establishing correspondence between OCT and fundus imagery. The proposed system also distinguishes between early, suspect and confirmed ARMD by correlating OCT B-scans with respective region of the fundus image. In first phase, proposed system uses different B-scan based features along with support vector machine (SVM) to detect the presence of drusens and classify it as ARMD or normal case. In case input OCT scan is classified as ARMD, region of interest from corresponding fundus image is considered for further evaluation. The analysis of fundus image is performed using contrast enhancement and adaptive thresholding to detect possible drusens from fundus image and proposed system finally classified it as early stage ARMD or advance stage ARMD. The proposed system is tested on local data set of 100 patients with100 fundus images and 6800 OCT B-scans. Proposed system detects ARMD with the accuracy, sensitivity, and specificity ratings of 98.0, 100, and 97.14%, respectively.

62 RADIOLOGY AND NUCLEAR MEDICINE↗

High resolution coherent diffractive imaging with a table-top extreme ultraviolet source

We demonstrate a resolution of 45 nm with a sample size down to 3 μm × 3 μm is achieved in a short exposure time of 2 s, from the diffraction pattern generated by a table-top high harmonic source at around 30 nm. By using a narrow-bandwidth focusing mirror, the diffraction pattern's quality is improved and the required exposure time is significantly reduced. In order to obtain a high quality of the reconstructed image, the ratio of the beam size to the sample size and the curvature of the focused beam need to be considered in the reconstruction process. This new experimental scheme is very promising for imaging sub-10 nm scale objects with a table-top source based on a small inexpensive femtosecond laser system.

75 CONDENSED MATTER PHYSICS, SUPERCONDUCTIVITY AND↗

Performance of Multilayer Monochromators for Hard X-Ray Imaging with Coherent Synchrotron Radiation

We present a study in which multilayers of different periodicity (from 2.5 to 5.5 nm), composition (W/Si, Mo/Si, Pd/B{sub 4}C, Ru/B{sub 4}C), and numbers of layers have been compared. Particularly, we chose mirrors with similar intrinsic quality (roughness and reflectivity) to study their performance (flatness and coherence of the outgoing beam) as monochromators in synchrotron radiography. The results indicate that material composition is the dominating factor for the performance. This is important to consider for future developments in synchrotron-based hard x-ray imaging methods. In these techniques, multilayer monochromators are popular because of their good tradeoff between spectral bandwidth and photon flux density of the outgoing beam, but sufficient homogeneity and preservation of the coherent properties of the reflected beam are major concerns. The experimental results we collected may help scientists and engineers specify multilayer monochromators and can contribute to better exploitation of the advantages of multilayer monochromators in microtomography and other full-field imaging techniques.

43 PARTICLE ACCELERATORS↗

Coherent optical imaging of moving objects hidden in a heavily scattering random medium

Experimental results are presented that provide insight into the physics of statistical imaging in heavily scattering random media based on measured speckle correlations as a function of the change in position of a moving object. In this way, definitive interpretation of a rather complex and earlier theory is achieved, making this work an experimental complement to that theory paper []. Motion could be natural, where the set of positions is estimated or separately obtained, or directed, where a mechanical stage can be used to adjust the object's position. In the experiment, a coherent laser illuminates two scattering diffusers, while an object is translated between them in the resulting speckled field and images are collected in a transmission configuration. Results are shown for various objects of differing size and geometry, allowing the theory to be validated and interpreted with new understanding. This work demonstrates imaging opportunities, and applications include material characterization, environmental imaging and sensing, and deep-tissue imaging. Published by the American Physical Society 2025

Hastings, Ryan L. (ORCID:0009000095977807)↗

ALMA Band-to-band Phase Referencing: Imaging Capabilities on Long Baselines and High Frequencies

High-frequency long-baseline experiments with the Atacama Large Millimeter/submillimeter Array were organized to test the high angular resolution imaging capabilities in the submillimeter wave regime using baselines up to 16 km. Four experiments were conducted, two Band 7 (289 GHz) and two Band 8 (405 GHz) observations. Phase correction using band-to-band (B2B) phase referencing was used with a phase calibrator only [[Formula]] away observed in Band 3 (96 GHz) and Band 4 (135 GHz), respectively. In Band 8, we achieved the highest resolution of 14 × 11 mas. We compared the synthesis images of the target quasar using 20 and 60 s switching cycle times in the phase referencing. In Band 7, the atmosphere had good stability in phase rms (<0.5 rad over 2 minutes), and there was little difference in image coherence between the 20 and 60 s switching cycle times. One Band 8 experiment was conducted under a worse phase rms condition (>1 rad over 2 minutes), which led to a significantly reduced coherence when using the 60 s switching cycle time. One of our four experiments indicates that the residual phase rms error after phase referencing can be reduced to 0.16 rad at 289 GHz in using the 20 s switching cycle time. Such conditions would meet the phase correction requirement of image coherence of >70% in Band 10, assuming a similar phase calibrator separation angle, emphasizing the need for such B2B phase referencing observing at high frequencies.

79 ASTRONOMY AND ASTROPHYSICS↗

Continuous motion scan ptychography: Characterization for increased speed in coherent x-ray imaging

Ptychography is a coherent diffraction imaging (CDI) method for extended objects in which diffraction patterns are acquired sequentially from overlapping coherent illumination spots. The object’s complex transmission function can be reconstructed from those diffraction patterns at a spatial resolution limited only by the scattering strength of the object and the detector geometry. Most experiments to date have positioned the illumination spots on the sample using a move-settle-measure sequence in which the move and settle steps can take longer to complete than the measure step. We describe here the use of a continuous “fly-scan” mode for ptychographic data collection in which the sample is moved continuously, so that the experiment resembles one of integrating the diffraction patterns from multiple probe positions. This allows one to use multiple probe mode reconstruction methods to obtain an image of the object and also of the illumination function. We show in simulations, and in x-ray imaging experiments, some of the characteristics of fly-scan ptychography, including a factor of 25 reduction in the data acquisition time. This approach will become increasingly important as brighter x-ray sources are developed, such as diffraction limited storage rings.

43 PARTICLE ACCELERATORS↗

Ultrafast Bragg coherent diffraction imaging of epitaxial thin films using deep complex-valued neural networks

Abstract Domain wall structures form spontaneously due to epitaxial misfit during thin film growth. Imaging the dynamics of domains and domain walls at ultrafast timescales can provide fundamental clues to features that impact electrical transport in electronic devices. Recently, deep learning based methods showed promising phase retrieval (PR) performance, allowing intensity-only measurements to be transformed into snapshot real space images. While the Fourier imaging model involves complex-valued quantities, most existing deep learning based methods solve the PR problem with real-valued based models, where the connection between amplitude and phase is ignored. To this end, we involve complex numbers operation in the neural network to preserve the amplitude and phase connection. Therefore, we employ the complex-valued neural network for solving the PR problem and evaluate it on Bragg coherent diffraction data streams collected from an epitaxial La 2-x Sr x CuO 4 (LSCO) thin film using an X-ray Free Electron Laser (XFEL). Our proposed complex-valued neural network based approach outperforms the traditional real-valued neural network methods in both supervised and unsupervised learning manner. Phase domains are also observed from the LSCO thin film at an ultrafast timescale using the complex-valued neural network.

77 NANOSCIENCE AND NANOTECHNOLOGY↗