Integrated System and Application Continuous Performance Monitoring and Analysis Capability.
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Disclosed herein are systems and methods for associating metabolites with genes. In some embodiments, after potential metabolites are identified based on spectroscopy data of the content of an organism, possible reactions capable of producing the potential metabolites are determined. The possible reactions are compared to gene sequences in a database, and an association score for the likelihood that a gene sequence is related to the potential metabolites is calculated.
Energy system integration promises in-creased resiliency and the unlocking of synergies, while also contributing to our goal of decarbonization. It is enabled by both old and new technologies, glued together with data and digital services. Hydrolyzers, heat pumps, distributed renewable generation, smart buildings, and the digital grid edge are all currently the subject of integration with the power system and the energy sector at large. To plan and operate such a multidisciplinary and multisectoral system properly, insight, tools, and expertise are all needed. Further, this is exactly where the state of the art fails to deliver: tools for integrated energy systems (IESs) are still in their infancy, and many times, even academia treats these sectors separately, producing experts in each of them but not across.
We describe here the crossover from generalized to conventional hydrodynamics in nearly integrable systems. Integrable systems have infinitely many conserved quantities, which spread ballistically, in general. When integrability is broken, only a few of these conserved quantities survive. The remaining conserved quantities are generically transported diffusively; we further derive a compact and general diffusion equation for these. The diffusion constant depends on the matrix elements of the integrability-breaking perturbation; for a certain class of integrability-breaking perturbations, including long-range interactions, the diffusion constant can be expressed entirely in terms of generalized hydrodynamic data.
Integrated electricity and gas systems are constructed to facilitate the gas-fired generation, and the distributed operation of these integrated systems have received much attention due to the increased emphasis on data security and privacy between different agencies. This paper proposes an extended convex hull based method to address optimal energy flow problems for the integrated electricity and gas systems in a distributed manner. First, a multi-block electricity-gas system model is constructed by dividing the whole system into N blocks considering both physical and regional differences. This multi-block model is then convexified by replacing the nonconvex gas transmission equation with the extended convex hull-based constraints. The Jacobi-Proximal alternating direction method of multipliers algorithm is adopted to solve the convexified model and minimize its operation cost. Finally, the feasibility of the optimal solution for the convexified model is checked, and a sufficient condition is developed. If the sufficient condition is satisfied, the optimal solution for the original nonconvex problem can be recovered from that for the convexified problem. Simulation results demonstrate that the proposed method is tractable and effective in obtaining feasible optimal solutions for multi-block optimal energy flow problems.
Employing integrated energy systems (IESs) with nuclear power plants (NPPs) can improve NPP utilization by leveraging dedicated thermal and electric power delivery, but it may also increase operational safety risks. This paper presents a framework to identify and quantify hazards and risks for such IESs. The framework combines accidentology to review past industrial accidents with failure modes and effects analysis (FMEA) to identify potential future incidents. Hydrogen explosion and toxic chemical release hazards are of particular concern. Explosion consequences are quantified using the Bauwens-Dorofeev (Bauwens) and trinitrotoluene equivalent mass (TNT-EM) methods, while chemical release consequences are computed using the Gaussian atmospheric dispersion method. Operational disturbances from direct electrical and thermal integration that may affect NPP safety are modeled using probabilistic risk analysis (PRA). Hazards and risks are then evaluated for regulatory compliance. The framework is applied to IESs comprising pressurized or boiling water reactors supplying three levels of thermal and electrical power to industrial customers. Case studies include high-temperature steam electrolysis hydrogen plants of varying capacities and a synthetic fuel production plant. Sensitivity analysis examines piping component failures in the PRA model as a precursor to cost estimation for thermal extraction line design. Additionally, Fussel-Vessely (FV) and risk increase importance (RII) measures identify risk-informed design improvements for the thermal extraction system. FMEA highlights hazards such as loss of offsite power, prompt loss of electrical load, loss of thermal output, and immediate steam diversion, in addition to hydrogen explosions and toxic chemical releases. Both Bauwens and TNT-EM methods suggest maintaining several hundred meters of separation between the NPP and hydrogen facility to mitigate explosion risks. PRA results show a maximum initiating event frequency increase of 1.15% and an overall risk increase of 0.28%. Importance measure analysis identifies upstream pipe leak isolation components as critical. Evaluating the results against safety regulations, it is concluded that hazards and risks can be managed to comply with regulations through risk-informed thermal and electrical connection designs, component selection, maintenance programs, and safe separation distances between NPPs and integrated industrial facilities.
The integration of nuclear power into energy systems presents a promising avenue to address the growing global energy demands while minimizing greenhouse gas emissions. In this paper, we introduce a data-driven quasi-static surrogate model for nuclear-powered Integrated Energy Systems (IES) that comprises various components, including a small modular reactor (SMR), energy manifold (EM), balance of plant (BOP), high-temperature steam electrolysis (HTSE), and district heating (DH) system. Traditional physics-based models for these components often entail significant computational overhead and time consumption, necessitating the development of efficient surrogate models. The development of a complete surrogate model for the IES involves the creation of individual surrogate models for each component, leveraging machine learning techniques and simulated data. These isolated surrogate models are subsequently integrated, enabling a holistic view of the IES and reducing the computational burden associated with detailed physics-based simulations. This paper outlines the development process, validation, and the performance evaluation of the surrogate models. The findings shed light on the accuracy and applicability of the surrogate models in practical scenarios, demonstrating their potential to expedite the analysis of nuclear-powered IES and inform future research and development efforts.
The integration of nuclear power into energy systems presents a promising avenue to address the growing global energy demands while minimizing greenhouse gas emissions. In this paper, we introduce a data-driven quasi-static surrogate model for nuclear-powered Integrated Energy Systems (IES) that comprises various components, including a small modular reactor (SMR), steam manifold, balance of plant (BOP), high-temperature steam electrolysis (HTSE), and district heating (DH) system. Traditional physics-based models for these components often entail significant computational resource and time consumption, necessitating the development of efficient surrogate models. The development of a complete surrogate model for the IES involves the creation of individual surrogate models for each component, leveraging machine learning techniques and simulated data. These isolated surrogate models are subsequently integrated, enabling a holistic view of the IES and reducing the computational burden associated with detailed physics-based simulations. This paper outlines the development process, validation, and the performance evaluation of the surrogate models. The exceptional performance, with low root-mean-squared errors and R-squared scores of at least 99.8% across all individual surrogate models, underscores their accuracy and practical applicability. These results demonstrate the potential of these models to expedite the analysis of nuclear-powered IES, offering insights that can shape future research and development efforts.
Integrative modeling computes a model based on varied types of input information, be it from experiments or prior models. Often, a type of input information will be best handled by a specific modeling software package. In such a case, we desire to integrate our integrative modeling software package, Integrative Modeling Platform (IMP), with software specialized to the computational demands of the modeling problem at hand. After several attempts, however, we have concluded that even in collaboration with the software's developers, integration is either impractical or impossible. The reasons for the intractability of integration include software incompatibilities, differing modeling logic, the costs of collaboration, and academic incentives. In the integrative modeling software ecosystem, several large modeling packages exist with often redundant tools. So we reason, therefore, that the other development groups have similarly concluded that the benefit of integration does not justify the cost. As a result, modelers are often restricted to the set of tools within a single software package. The inability to integrate tools from distinct software negatively impacts the quality of the models and the efficiency of the modeling. As the complexity of modeling problems grows, we seek to galvanize developers and modelers to consider the long-term benefit that software interoperability yields. In this article, we formulate a demonstrative set of software standards for implementing a model search using tools from independent software packages and discuss our efforts to integrate IMP and the crystallography suite Phenix within the Bayesian modeling framework.
This chapter focuses on material extrusion additive manufacturing (AM) processes for polymers and composite materials. Different extrusion AM platforms, along with their operating mechanism concepts, processing capabilities, and limitations, are discussed here. This chapter also covers state-of-the-art developments in new areas such as hybrid systems, integrated systems, and automation, which facilitate the integration of extrusion-based AM processes into smart manufacturing or Industry 4.0. Following this, a comprehensive discussion on materials development, criteria for successful printing of different materials (thermoplastics, thermosets, and their composites), key factors influencing printing, and material-related challenges in extrusion AM is presented. Finally, a brief overview of current and future potential applications of material extrusion AM technology is provided.
This work adapts historical literature and existing phenomena identification and ranking tables (PIRT) to be applicable to a novel nuclear power plant (NPP) and chemical or thermal process integrated energy system (IES), particularly focusing on the process heat and heat transport system failure events that are not a concern during normal NPP operation but become vital when an IES is considered. Nuclear energy has been suggested to go beyond base-load applications and be used for hydrogen co-generation systems, amongst other IESs. Prior to the implementation of nuclear IESs, sufficient analysis must be performed on accident events to ensure public safety. The events considered were deemed important because of their potential to damage systems, structures, and components (SSCs). Process thermal events of concern include loss of heat load and temperature transient events. Loss of heat load events were characterized as having high importance and being well understood. Temperature transient events may be further categorized by the cyclic loading and harmonics phenomena. Cyclic loading issues were classified as medium to high importance with knowledge gaps existing regarding fatigue and low power operation, while harmonics phenomena were classified as low importance and are well understood. Heat transport system failure events of concern include intermediate and process heat exchanger failures, mass addition to reactor coolant, ingress of material from thermal manifold/energy storage, and loss of intermediate fluid. Furthermore, these events tended to be of high or medium importance, with some knowledge gaps needing to be filled for individual reactor systems due to unique designs.
Leveraging the synergies among different energy technologies, Integrated Energy Systems (IES) can achieve greater efficiency, higher flexibility, and better CO2 removal concurrently. However, system integration in reality faces various challenges and difficulties. To integrate with other components, off-the-shelf equipment needs case-by-case modifications and redesigns. This presentation will use two integrated systems as examples to reveal the challenges in system integration.
Integrated energy systems (IES)s are crucial for enhancing the economy and efficiency of power generation sources (e.g., nuclear energy) necessary to unleash American energy dominance. These systems can be integrated with thermal energy storage (TES) and intermittent renewable energies to optimize overall energy use, peak-load regulation, and demand-side responses. However, the stabilization of energy generation, transport, and utilization introduces operational complexities that exceed the challenges of managing each sub-component individually. Currently, though IESs rely on human operators for efficiency and stability, reducing human error risk and enhancing performance through automation is highly desirable. Recent advances at Idaho National Laboratory have demonstrated successful control of the Thermal Energy Distributed System (TEDS). However, the automatic control system depends on a deterministic Sparse Identification of Nonlinear Dynamics with Control (SINDyC) model, which are trained based on simulation data from physics-based simulations. Because of uncertainties in physics-based simulation, SINDyC model results in large discrepancies against experimental data and cannot be reliably used in automatic control. In this paper, we present an innovative approach to address these discrepancies by quantifying uncertainties and developing a more robust model. We first generated trajectories by using first-principles physics codes to encapsulate the experiment. Next, we trained thousands of models by randomly sampling these trajectories. We then collapsed all those models into one probabilistic SINDyC by fitting a multivariate Gaussian distribution onto the resulting coefficient’s distribution. Despite its simplicity, our approach successfully produced 95% confidence intervals that captured the experimental trajectories. It even did so with a higher probability and better U-pooling score across six of the seven relevant quantities of interest (QoIs), as compared to other classical approaches. In conclusion, ongoing research is focusing on generating new experimental trajectories to validate this approach, and on employing Bayesian calibration to refine parametric uncertainties and guide future model development efforts.
The electric power infrastructure, originally designed and built on large-scale power plants, is evolving into a more resilient power generation and delivery system in which millions of smaller units of distributed energy generation resources units will be installed in sub-transmission and distribution networks. In order to control, manage and optimize the future grid, a hierarchical design is presented in this chapter which enables the distributed control on grid edge while inheriting the existing centralized control structure. This layered design of large-scale power system operation and control uses the following principle: reactive power control is treated as a primary control for voltage stability, and the real power control is primarily a grid-level control but can also be a supplementary control for voltage support in the case of insufficient reactive power control capacity. For the purpose of active control and operation at the distribution level, a recursive power network model is derived from nodal injection and branch power flow models. Based on the model, the proposed algorithms of hierarchical control, grid-edge inference and dynamic hosting allowance are developed and presented for multi-level controlled operation. And, a co-simulation architecture of integrated T&D system is presented to validate and demonstrate the feasibility and scalability of proposed algorithms.
Many nuclear facilities, such as spent fuel storage dry casks and nuclear reactor pressure vessels, are entirely sealed by metal layers to prevent harmful radiation. For safety and security operations, the temperature, pressure, radiation, and humidity inside the vessel needs to be closely monitored. However, no practical technology is currently available to realize the through-wall data communication and monitoring for these vessels due to the inside harsh environment of high temperature and nuclear radiation. In this paper, an innovative self-powered wireless through-wall data communication system for the nuclear environment is presented, which demonstrates a successful solution to such challenges. The presented system is composed of four modules, i.e., energy harvester with power management circuits, ultrasound wireless communication using high-temperature piezoelectric transducers, electronic circuits for sensing and data transmission, and radiation shielding for electronics. Here, constitutive functions of each module were firstly designed and followed by the system integration. Experiments were conducted subsequently to validate the designed functions and evaluate the performance of the integrated system. Results showed that the average power of over 40 mW was harvested from the thermal flow inside the nuclear spent fuel canisters which could provide enough energy to operate the sensing and data communication systems. The gamma radiation test results showed that the thermoelectric energy harvester and ultrasound transceivers can withstand radiation dosing over 100 Mrad. Furthermore, temperature shock tests demonstrated that the entire system including the shielded electronics can survive and maintain their functionalities at temperatures as high as 195°C. Under the in-lab mocked-up high temperature conditions and radiation shielding, the proposed system is foreseen to survive and operate stably for fifty years inside a nuclear spent fuel canister, and send the frequency modulated data out of the canister for 3 s in every 10 min.
Integrated energy systems (IESs) seek to minimize power generating costs in future power grids through the coupling of different energy technologies. To accommodate fluctuations in load demand due to the penetration of renewable energy sources, flexible operation capabilities must be fully exploited, and even power plants that are traditionally considered as base-load units need to be operated according to unconventional paradigms. Thermomechanical loads induced by frequent power adjustments can accelerate the wear and tear. If a unit is flexibly operated without respecting limits on materials, the risk of failures of expensive components will eventually increase, nullifying the additional profits ensured by flexible operation. In addition to the bounds on power variations (explicit constraints),the solution of the unit dispatch problem needs to meet the limits on the variation of key process variables, including temperature, pressure and flow rate (implicit constraints).The FARM (Feasible Actuator Range Modifier) module was developed to enable existing optimization algorithms to identify solutions to the unit dispatch problem that are both economically favorable and technologically sustainable. Thanks to the iterative dispatcher–validator scheme, FARM permits addressing all the imposed constraints without excessively increasing the computational costs. In this work, the algorithms constituting the module are described, and the performance was assessed by solving the unit dispatch problem for an IES composed of three units, i.e., balance of plant, gas turbine, and high-temperature steam electrolysis. Finally, the FARM module provides dedicated tools for visualizing the response of the constrained variables of interest during operational transients and a tool aiding the operator at making decisions. These techniques might represent the first step towards the deployment of an ecological interface design (EID) for IES units.