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Vestibular function in the space environment
The present work presents new results about the interdependence of optical illusory sensations and eye movements in man. To establish to what degree certain illusions previously obtained during centrifugation and parabolic flight can be explained by eye movements and by neuronal integration in the brain, real eye movements were measured as they occurred in the dark without optical fixation, during rectilinear accelerations on the ground, and during weightlessness in parabolic flight. Results provide valuable insight into normal vestibular function as well as resolution of within-the-eye and behind-the-eye contributions to the above illusions.
Cell-Mediated Immune Function and Cytokine Regulation During Space Flight
The changes in immune function which occur during space flight potentially expose the crews to an increased risk for development of illness. Decreased cellular immune function has been repeatedly documented after space flight and confirmed during flight by in vivo delayed-type hypersensitivity testing. However, correlation of immune changes with a clinically significant risk factor has not yet been performed. Our hypothesis is that space flight induces a decrease in cell-mediated immune function accompanied by a shift from a type 1 cytokine pattern (favoring cell-mediated immunity) to a type 2 cytokine pattern (favoring humoral immunity). We further hypothesize that reactivation of latent viruses will occur during space flight in association with the decreased cellular immunity. To test these hypotheses, we will determine the effects of space flight on cell-mediated immunity and viral reactivation. We will utilize delayed-type hypersensitivity testing as an in vivo measure of integrated cell-mediated immune function. The production of cytokines and immunoregulatory factors by lymphocytes and monocytes will be measured to determine whether changes in cytokine patterns are associated with the space flight-induced immune dysregulation. Correlation of antigen-specific immune changes with reactivation of latent herpes viruses will be determined by measuring peripheral levels of viral (CMV, VZV, EBV) antigen-specific T cells and comparing to the levels of EBV-infected B-cells by fluorescence in situ hybridization and flow cytometry. A comparison of cell-mediated immune function, cytokine regulation and viral reactivation will provide new insights into crew member health risks during flight.
Optimization of the performance of a tandem microchannel plate detector as a function of interplate spacing and voltage
The effect of varying the size of the gap voltage and spacing on the performance of a tandem pair of microchannel plates (MCP) is investigated. Results show that increasing the voltage in the gap increases the gain of the pair and also produces a narrower Gaussian pulse-height distribution, although beyond a critical voltage the gain of the channel plate pair is found to plateau. A model is developed which explains the nonlinear gain behavior of individual microchannels and the behavior of the electron cloud emitted from the first MCP as it spreads out between the two MCPs and hits the surface of the second. The model calculates the plateau voltage as a function of the gap size, the gain of each MCP, and the diameter of the channels, and is found to show good agreement with the observed results. It is concluded that interplate gaps of up to several millimeters can be accommodated without a significant degradation in pulse-height distribution.
Physiological principles of vestibular function on earth and in space
Physiological mechanisms underlying vestibular function have important implications for our ability to understand, predict, and modify balance processes during and after spaceflight. The microgravity environment of space provides many unique opportunities for studying the effects of changes in gravitoinertial force on structure and function of the vestibular system. Investigations of basic vestibular physiology and of changes in reflexes occurring as a consequence of exposure to microgravity have important implications for diagnosis and treatment of vestibular disorders in human beings. This report reviews physiological principles underlying control of vestibular processes on earth and in space. Information is presented from a functional perspective with emphasis on signals arising from labyrinthine receptors. Changes induced by microgravity in linear acceleration detected by the vestibulo-ocular reflexes. Alterations of the functional requirements for postural control in space are described. Areas of direct correlation between studies of vestibular reflexes in microgravity and vestibular disorders in human beings are discussed.
Periodic motions in banach space and applications to functional-differential equations.
Periodic motions in Banach space and applications to autonomous functional-differential equations
The state space and transfer function approaches in practical linear multivariable systems design.
A procedure using transfer function formalism for stabilizing a multivariable feedback system with significant plant uncertainty is presented. The method shapes nominal loop functions and decreases their magnitudes with frequency in such a manner that the system remains stable throughout the plant uncertainty range. An example illustrates the application of the described procedure.
Study to investigate and evaluate means of optimizing the radar function for the space shuttle
Results are discussed of a study to define a radar and antenna system which best suits the space shuttle rendezvous requirements. Topics considered include antenna characteristics and antenna size tradeoffs, fundamental sources of measurement errors inherent in the target itself, backscattering crosssection models of the target and three basic candidate radar types. Antennas up to 1.5 meters in diameter are within specified installation constraints, however, a 1 meter diameter paraboloid and a folding, four slot backfeed on a two gimbal mount implemented for a spiral acquisition scan is recommended. The candidate radar types discussed are: (1) noncoherent pulse radar (2) coherent pulse radar and (3) pulse Doppler radar with linear FM ranging. The radar type recommended is a pulse Doppler with linear FM ranging. Block diagrams of each radar system are shown.
Study to investigate and evaluate means of optimizing the radar function for the space shuttle
A detailed analysis of the spiral scan was performed for antenna sizes ranging from 20 inches to 36 inches in diameter and for search angles characteristic of both the radar and the communication acquisition modes. The power budgets for passive target radar detection were calculated for antenna diameters ranging from 20 to 36 inches. Dwell times commensurate with spiral scan were used for these budget calculations. The signal design for the candidate pulse Doppler system is summarized. Ground return analysis carried out for the passive target radar mode is examined, and the details are presented. A concluding description of the proposed candidate radar/communication system configuration is given.
Study to investigate and evaluate means of optimizing the Ku-band combined radar/communication functions for the space shuttle
The performance of the space shuttle orbiter's Ku-Band integrated radar and communications equipment is analyzed for the radar mode of operation. The block diagram of the rendezvous radar subsystem is described. Power budgets for passive target detection are calculated, based on the estimated values of system losses. Requirements for processing of radar signals in the search and track modes are examined. Time multiplexed, single-channel, angle tracking of passive scintillating targets is analyzed. Radar performance in the presence of main lobe ground clutter is considered and candidate techniques for clutter suppression are discussed. Principal system parameter drivers are examined for the case of stationkeeping at ranges comparable to target dimension. Candidate ranging waveforms for short range operation are analyzed and compared. The logarithmic error discriminant utilized for range, range rate and angle tracking is formulated and applied to the quantitative analysis of radar subsystem tracking loops.
Study to investigate and evaluate means of optimizing the Ku-band combined radar/communication functions for the space shuttle
The Ku band radar system on the shuttle orbiter operates in both a search and a tracking mode, and its transmitter and antennas share time with the communication mode in the integrated system. The power allocation properties and the Costa subloop subcarrier tracking performance associated with the baseline digital phase shift implementation of the three channel orbiter Ku band modulator are discussed.
Critical point behavior of objective functions defined on spaces of multivariable systems
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Spacestation: The next logical step
The concept of a U.S. space station is discussed. The design, how it will work, space laboratory functions, commerce in space, and international cooperation are discussed.
Functional Task Test: 3. Skeletal Muscle Performance Adaptations to Space Flight
The functional task test is a multi-disciplinary study investigating how space-flight induced changes to physiological systems impacts functional task performance. Impairment of neuromuscular function would be expected to negatively affect functional performance of crewmembers following exposure to microgravity. This presentation reports the results for muscle performance testing in crewmembers. Functional task performance will be presented in the abstract "Functional Task Test 1: sensory motor adaptations associated with postflight alternations in astronaut functional task performance." METHODS: Muscle performance measures were obtained in crewmembers before and after short-duration space flight aboard the Space Shuttle and long-duration International Space Station (ISS) missions. The battery of muscle performance tests included leg press and bench press measures of isometric force, isotonic power and total work. Knee extension was used for the measurement of central activation and maximal isometric force. Upper and lower body force steadiness control were measured on the bench press and knee extension machine, respectively. Tests were implemented 60 and 30 days before launch, on landing day (Shuttle crew only), and 6, 10 and 30 days after landing. Seven Space Shuttle crew and four ISS crew have completed the muscle performance testing to date. RESULTS: Preliminary results for Space Shuttle crew reveal significant reductions in the leg press performance metrics of maximal isometric force, power and total work on R+0 (p<0.05). Bench press total work was also significantly impaired, although maximal isometric force and power were not significantly affected. No changes were noted for measurements of central activation or force steadiness. Results for ISS crew were not analyzed due to the current small sample size. DISCUSSION: Significant reductions in lower body muscle performance metrics were observed in returning Shuttle crew and these adaptations are likely contributors to impaired functional tasks that are ambulatory in nature (See abstract Functional Task Test: 1). Interestingly, no significant changes in central activation capacity were detected. Therefore, impairments in muscle function in response to short-duration space flight are likely myocellular rather than neuromotor in nature.
Predicting Team Functioning in Long Term Space Missions Using Acoustic and Linguistic Measures
Maintaining optimal team functioning is critical for long-duration space exploration missions, yet traditional monitoring methods, such as self-reports and wearable sensors, often impose operational burdens or suffer from bias. This paper investigates a non-intrusive speech-based artificial intelligence (AI) framework to predict degradations in team functioning using data from the Human Exploration Research Analog (HERA) of the U.S. National Aeronautics and Space Administration (NASA). Using acoustic features, linguistic descriptors, and semantic embeddings, we evaluate static non-linear and temporal machine learning models to predict both objective (task accuracy) and subjective (self-reported efficacy and cohesion) team functioning outcomes. Results indicate that temporal models outperform static approaches, with prediction of objective task accuracy in Team Interaction Battery (TIB) improving from near chance to 71%. Self-reported outcomes, including team efficacy and cohesion, are predicted more reliably than task performance, achieving balanced accuracies of up to 85.56% and 78.12%, respectively, and are found to be most strongly associated with acoustic features. In a second interdependent task, the MMSEV–EVA, accuracies of up to 78% are achieved using temporal models with acoustic features. Furthermore, incorporating just 1–2 days of team-specific historical data systematically improved performance, and acoustic markers from informal pre-task interactions provided modest predictive gains. Finally, while automated preprocessing yielded viable accuracy, humancorrected data provided moderate performance gains, though transcription error rates did not significantly correlate with model performance. These findings highlight the potential of speech as a passive, high-fidelity monitoring tool for autonomous habitats.
Introduction - Space Station and platform roles in supporting future space endeavors
The function of the Space Station and a platform is studied. The development of an earth observing instrument platform in a near-polar geosynchronous orbit to provide data about the earth is examined. The establishment of a permanently manned Space Station will allow development of commercial laboratories. Architectural requirements for servicing, transportation, and assembly on the Space Station are analyzed. The study of physiological and psychological effects due to weightlessness can be conducted on the Space Station. Developments in space knowledge and technology that are possible with the Space Station are discussed.
Functional Task Test: 1. Sensorimotor changes Associated with Postflight Alterations in Astronaut Functional Task Performance
Space flight is known to cause alterations in multiple physiological systems including changes in sensorimotor, cardiovascular, and neuromuscular systems. These changes may affect a crewmember s ability to perform critical mission tasks immediately after landing on a planetary surface. The overall goal of this project is to determine the effects of space flight on functional tests that are representative of high priority exploration mission tasks and to identify the key underlying physiological factors that contribute to decrements in performance. This presentation will focus on the sensorimotor contributions to postflight functional performance.