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At least 145 records · Page 8

Search for dark photons in Higgs boson production via vector boson fusion in proton-proton collisions at $ \sqrt{s} $ = 13 TeV

A search is presented for a Higgs boson that is produced via vector boson fusion and that decays to an undetected particle and an isolated photon. The search is performed by the CMS collaboration at the LHC, using a data set corresponding to an integrated luminosity of 130 fb$^{−1}$, recorded at a center-of-mass energy of 13 TeV in 2016–2018. No significant excess of events above the expectation from the standard model background is found. The results are interpreted in the context of a theoretical model in which the undetected particle is a massless dark photon. An upper limit is set on the product of the cross section for production via vector boson fusion and the branching fraction for such a Higgs boson decay, as a function of the Higgs boson mass. For a Higgs boson mass of 125 GeV, assuming the standard model production rates, the observed (expected) 95% confidence level upper limit on the branching fraction is 3.5 (2.8)%. This is the first search for such decays in the vector boson fusion channel. Combination with a previous search for Higgs bosons produced in association with a Z boson results in an observed (expected) upper limit on the branching fraction of 2.9 (2.1)% at 95% confidence level.[graphic not available: see fulltext]

72 PHYSICS OF ELEMENTARY PARTICLES AND FIELDS↗

Search for nonresonant Higgs boson pair production in final states with two bottom quarks and two photons in proton-proton collisions at $ \sqrt{s} $ = 13 TeV

A search for nonresonant production of Higgs boson pairs via gluon-gluon and vector boson fusion processes in final states with two bottom quarks and two photons is presented. The search uses data from proton-proton collisions at a center-of-mass energy of $ \sqrt{s} $ = 13 TeV recorded with the CMS detector at the LHC, corresponding to an integrated luminosity of 137 fb$^{−1}$. No significant deviation from the background-only hypothesis is observed. An upper limit at 95% confidence level is set on the product of the Higgs boson pair production cross section and branching fraction into $ \gamma \gamma \mathrm{b}\overline{\mathrm{b}} $. The observed (expected) upper limit is determined to be 0.67 (0.45) fb, which corresponds to 7.7 (5.2) times the standard model prediction. This search has the highest sensitivity to Higgs boson pair production to date. Assuming all other Higgs boson couplings are equal to their values in the standard model, the observed coupling modifiers of the trilinear Higgs boson self-coupling κ$_{λ}$ and the coupling between a pair of Higgs bosons and a pair of vector bosons c$_{2V}$ are constrained within the ranges −3.3 < κ$_{λ}$< 8.5 and −1.3 < c$_{2V}$< 3.5 at 95% confidence level. Constraints on κ$_{λ}$ are also set by combining this analysis with a search for single Higgs bosons decaying to two photons, produced in association with top quark-antiquark pairs, and by performing a simultaneous fit of κ$_{λ}$ and the top quark Yukawa coupling modifier κ$_{t}$.[graphic not available: see fulltext]

72 PHYSICS OF ELEMENTARY PARTICLES AND FIELDS↗

Search for nonresonant Higgs boson pair production in the four leptons plus twob jets final state in proton-proton collisions at $\sqrt{s}$ = 13 TeV

The first search for nonresonant production of Higgs boson pairs (HH) with one H decaying into four leptons and the other into a pair of b quarks is presented, using proton-proton collisions recorded at a center-of-mass energy of √s = 13 TeV by the CMS experiment. The analyzed data correspond to an integrated luminosity of 138 fb–1. A 95% confidence level upper limit of 32.4 is set on the signal strength modifier μ, defined as the ratio of the observed HH production rate in the HH → ZZ*b$\overline{b}$ → 4lb$\overline{b}$ decay channel to the standard model (SM) expectation. Possible modifications of the H trilinear coupling λHHH with respect to the SM value are investigated. The coupling modifier κ λ , defined as λHHH divided by its SM prediction, is constrained to be within the observed (expected) range –8.8 (–9.8) < κ λ < 13.4 (15.0) at 95% confidence level.

72 PHYSICS OF ELEMENTARY PARTICLES AND FIELDS↗

Search for the HH → $ b\overline{b}b\overline{b} $ process via vector-boson fusion production using proton-proton collisions at $ \sqrt{s} $ = 13 TeV with the ATLAS detector

A search for Higgs boson pair production via vector-boson fusion (VBF) in the $ b\overline{b}b\overline{b} $ final state is carried out with the ATLAS experiment using 126 fb –1 of proton- proton collision data delivered at $ \sqrt{s} $ = 13 by the Large Hadron Collider. This search is sensitive to VBF production of additional heavy bosons that may decay into Higgs boson pairs, and in a non-resonant topology it can constrain the quartic coupling between the Higgs bosons and vector bosons. No significant excess relative to the Standard Model expectation is observed, and limits on the production cross-section are set at the 95% confidence level for a heavy scalar resonance in the context of an extended Higgs sector, and for non-resonant Higgs boson pair production. Interpretation in terms of the coupling between a Higgs boson pair and two vector bosons is also provided: coupling values normalised to the Standard Model expectation of κ 2V < –0.76 and κ 2V > 2.90 are excluded at the 95% confidence level in data.

72 PHYSICS OF ELEMENTARY PARTICLES AND FIELDS↗

Combination of searches for Higgs boson decays into a photon and a massless dark photon using pp collisions at $\sqrt{\textrm{s}}$ = 13 TeV with the ATLAS detector

A combination of searches for Higgs boson decays into a visible photon and a massless dark photon (H → γγd) is presented using 139 fb –1 of proton-proton collision data at a centre-of-mass energy of $\sqrt{\textrm{s}}$ = 13 TeV recorded by the ATLAS detector at the Large Hadron Collider. The observed (expected) 95% confidence level upper limit on the Standard Model Higgs boson decay branching ratio is determined to be B(H → γγ d ) < 1.3% (1.5)%. The search is also sensitive to higher-mass Higgs bosons decaying into the same final state. The observed (expected) 95% confidence level limit on the cross-section times branching ratio ranges from 16 fb (20 fb) for m H = 400 GeV to 1.0 fb (1.5 fb) for m H = 3 TeV. Results are also interpreted in the context of a minimal simplified model.

72 PHYSICS OF ELEMENTARY PARTICLES AND FIELDS↗

Search for dark matter produced in association with one or two top quarks in proton-proton collisions at $\sqrt{\text{s}}$ = 13 TeV

A search is performed for dark matter (DM) produced in association with a single top quark or a pair of top quarks using the data collected with the CMS detector at the LHC from proton-proton collisions at a center-of-mass energy of 13 TeV, corresponding to 138 fb −1 of integrated luminosity. An excess of events with a large imbalance of transverse momentum is searched for across 0, 1 and 2 lepton final states. Novel multivariate techniques are used to take advantage of the differences in kinematic properties between the two DM production mechanisms. No significant deviations with respect to the standard model predictions are observed. The results are interpreted considering a simplified model in which the mediator is either a scalar or pseudoscalar particle and couples to top quarks and to DM fermions. Axion-like particles that are coupled to top quarks and DM fermions are also considered. Expected exclusion limits of 410 and 380 GeV for scalar and pseudoscalar mediator masses, respectively, are set at the 95% confidence level. A DM particle mass of 1 GeV is assumed, with mediator couplings to fermions and DM particles set to unity. A small signal-like excess is observed in data, with the largest local significance observed to be 1.9 standard deviations for the 150 GeV pseudoscalar mediator hypothesis. Because of this excess, mediator masses are only excluded below 310 (320) GeV for the scalar (pseudoscalar) mediator. The results are also translated into model-independent 95% confidence level upper limits on the visible cross section of DM production in association with top quarks, ranging from 1 pb to 0.02 pb.

72 PHYSICS OF ELEMENTARY PARTICLES AND FIELDS↗

Search for lepton-flavor-violating tau decays to ℓα at Belle

We report a search for the lepton-flavor-violating decays τ ± → ℓ ± α (ℓ = e, μ), where α is an undetected spin-0 particle, such as an axion-like particle using 736 × 10 6 tau lepton pairs collected by the Belle detector at the KEKB asymmetric-energy e + e − collider. We find no evidence of signal and obtain the most stringent upper limits on the branching fractions at 95% confidence level: $\mathcal{B}$ (τ ± → e ± α) < (0.4–6.4) × 10 −4 and $\mathcal{B}$ (τ ± → μ ± α) < (0.2–3.5) × 10 −4 at 95% confidence level for an α mass in the range 0.0 ≤ m α ≤ 1.6 GeV/c 2 .

tau physics↗

A search for microscopic black holes, string balls, and sphalerons in proton-proton collisions at $\sqrt{s}=13$ TeV

A search for microscopic black holes, string balls, and electroweak sphalerons using proton-proton collisions at $\sqrt{s}=13$ TeV recorded with the CMS detector at the CERN LHC during the 2016–2018 data taking, and corresponding to an integrated luminosity of 138 fb −1 , is presented. Two search strategies based on control samples in data are used. Model-independent limits on the cross section of physics phenomena with multiple energetic jets, leptons, and photons are set using a method that relies on the shape invariance of the scalar sum of the transverse momenta of all objects in the event. Model-dependent limits on black hole and sphaleron production are set using a newly introduced method that has been developed for the identification of collider events with distinct kinematic features by separating them into classes based on phase space proximity. In the context of models with large extra dimensions, semiclassical black holes and string balls with masses below 8.4–11.4 TeV and 9.0–10.7 TeV, respectively, are excluded at 95% confidence level, significantly extending the reach beyond previous searches. Results of a dedicated search for electroweak sphalerons are used to derive an upper limit of 0.0034 at 95% confidence level on the fraction of quark-quark interactions, with a center-of-mass energy above the nominal sphaleron transition energy threshold of 9 TeV, that result in a sphaleron transition.

Beyond Standard Model↗

Search for a resonance decaying to a W boson and a photon in proton-proton collisions at $\sqrt{s}$ = 13 TeV using leptonic W boson decays

A search for a new charged particle X with mass between 0.3 and 2.0 TeV decaying to a W boson and a photon is presented, using proton-proton collision data at a center-of-mass energy of 13 TeV, collected by the CMS experiment and corresponding to an integrated luminosity of 138 fb$^{-1}$. Particle X has electric charge $\pm$ 1 and is assumed to have spin 0. The search is performed using the electron and muon decays of the W boson. No significant excess above the predicted background is observed. The upper limit at 95% confidence level on the product of the production cross section of the X and its branching fraction to a W boson and a photon is found to be 94 (137) fb for a 0.3 TeV resonance and 0.75 (0.81) fb for a 2.0 TeV resonance, for an X width-to-mass ratio of 0.01% (5%). This search presents the most stringent constraints to date on the existence of such resonances across the probed mass range. A statistical combination with an earlier study based on the hadronic decay mode of the W boson is also performed, and the upper limit at 95% confidence level for a 2.0 TeV resonance is reduced to 0.50 (0.63) fb for an X width-to-mass ratio of 0.01% (5%).

72 PHYSICS OF ELEMENTARY PARTICLES AND FIELDS↗

Search for Higgs boson pair production with one associated vector boson in proton-proton collisions at $ \sqrt{s} $ = 13 TeV

A search for Higgs boson pair (HH) production in association with a vector boson V (W or Z boson) is presented. The search is based on proton-proton collision data at a center-of-mass energy of 13 TeV, collected with the CMS detector at the LHC, corresponding to an integrated luminosity of 138 fb$^{−1}$. Both hadronic and leptonic decays of V bosons are used. The leptons considered are electrons, muons, and neutrinos. The HH production is searched for in the $ \textrm{b}\overline{\textrm{b}}\textrm{b}\overline{\textrm{b}} $ decay channel. An observed (expected) upper limit at 95% confidence level of VHH production cross section is set at 294 (124) times the standard model prediction. Constraints are also set on the modifiers of the Higgs boson trilinear self-coupling, k$_{λ}$, assuming k$_{2V}$ = 1, and vice versa on the coupling of two Higgs bosons with two vector bosons, k$_{2V}$. The observed (expected) 95% confidence intervals of these coupling modifiers are −37.7 < k$_{λ}$ < 37.2 (−30.1 < k$_{λ}$ < 28.9) and −12.2 < k$_{2V}$ < 13.5 (−7.2 < k$_{2V}$ < 8.9), respectively.[graphic not available: see fulltext]

72 PHYSICS OF ELEMENTARY PARTICLES AND FIELDS↗

Search for a heavy pseudoscalar Higgs boson decaying to a 125 GeV Higgs boson and a Z boson in final states with two tau and two light leptons in proton-proton collisions at $\sqrt{s} = 13$ TeV

A search for a heavy pseudoscalar Higgs boson, A, decaying to a 125 GeV Higgs boson h and a Z boson is presented. The h boson is identified via its decay to a pair of tau leptons, while the Z boson is identified via its decay to a pair of electrons or muons. The search targets the production of the A boson via the gluon-gluon fusion process, gg → A, and in association with bottom quarks, $b\overline{b}A$. The analysis uses a data sample corresponding to an integrated luminosity of 138 fb −1 collected with the CMS detector at the CERN LHC in proton-proton collisions at a centre-of-mass energy of $\sqrt{s} = 13$ TeV. Constraints are set on the product of the cross sections of the A production mechanisms and the A → Zh decay branching fraction. The observed (expected) upper limit at 95% confidence level ranges from 0.049 (0.060) pb to 1.02 (0.79) pb for the gg → A process and from 0.053 (0.059) pb to 0.79 (0.61) pb for the $b\overline{b}A$ process in the probed range of the A boson mass, mA, from 225 GeV to 1 TeV. The results of the search are used to constrain parameters within the $M^{125}_{h,EFT}$ benchmark scenario of the minimal supersymmetric extension of the standard model. Values of tan β below 2.2 are excluded in this scenario at 95% confidence level for all mA values in the range from 225 to 350 GeV.

72 PHYSICS OF ELEMENTARY PARTICLES AND FIELDS↗

Search for a cH signal in the associated production of at least one charm quark with a Higgs boson in the diphoton decay channel in pp collisions at $\sqrt{s}=13$ TeV

This paper presents the first search for a cH signal sensitive to the coupling of the charm quark (c) to the Higgs boson (H) in the associated production of at least one charm quark with a Higgs boson decaying to two photons. The results are based on a data set of proton-proton collisions at a center-of-mass energy of 13 TeV collected with the CMS experiment at the LHC, corresponding to an integrated luminosity of 138 fb −1 . Assuming the standard model (SM) rates for all other Higgs boson production processes, the observed (expected) upper limit at 95% confidence level on the cH signal strength is 243 (355) times the SM prediction. Under the same assumption, the observed (expected) allowed interval on the Higgs boson to charm quark coupling modifier, κ c , is |κ c | < 38.1 (|κ c | < 72.5) at 95% confidence level.

72 PHYSICS OF ELEMENTARY PARTICLES AND FIELDS↗

Search for flavour-changing neutral $tqH$ interactions with $H$ → γγ in $pp$ collisions at $ \sqrt{s} $ = 13 TeV using the ATLAS detector

A search for flavour-changing neutral interactions involving the top quark, the Higgs boson and an up-type quark q (q = c, u) is presented. The proton-proton collision data set used, with an integrated luminosity of 139 fb –1 , was collected at $\sqrt{s}$ = 13 TeV by the ATLAS experiment at the Large Hadron Collider. Both the decay process t → qH in $t\bar{t}$ production and the production process pp → tH, with the Higgs boson decaying into two photons, are investigated. No significant excess is observed and upper limits are set on the t → cH and the t → uH branching ratios of 4.3 × 10 –4 and 3.8 × 10 –4 , respectively, at the 95% confidence level, while the expected limits in the absence of signal are 4.7 × 10 –4 and 3.9 × 10 –4 . Combining this search with ATLAS searches in the H → τ + τ – and H → $b\bar{b}$ final states yields observed (expected) upper limits on the t → cH branching ratio of 5.8 × 10 –4 (3.0 × 10 –4 ) at the 95% confidence level. The corresponding observed (expected) upper limit on the t → uH branching ratio is 4.0 × 10 –4 (2.4 × 10 –4 ).

72 PHYSICS OF ELEMENTARY PARTICLES AND FIELDS↗

Establishing performance metrics for quantitative non-targeted analysis: a demonstration using per- and polyfluoroalkyl substances

Abstract Non-targeted analysis (NTA) is an increasingly popular technique for characterizing undefined chemical analytes. Generating quantitative NTA (qNTA) concentration estimates requires the use of training data from calibration “surrogates,” which can yield diminished predictive performance relative to targeted analysis. To evaluate performance differences between targeted and qNTA approaches, we defined new metrics that convey predictive accuracy, uncertainty (using 95% inverse confidence intervals), and reliability (the extent to which confidence intervals contain true values). We calculated and examined these newly defined metrics across five quantitative approaches applied to a mixture of 29 per- and polyfluoroalkyl substances (PFAS). The quantitative approaches spanned a traditional targeted design using chemical-specific calibration curves to a generalizable qNTA design using bootstrap-sampled calibration values from “global” chemical surrogates. As expected, the targeted approaches performed best, with major benefits realized from matched calibration curves and internal standard correction. In comparison to the benchmark targeted approach, the most generalizable qNTA approach (using “global” surrogates) showed a decrease in accuracy by a factor of ~4, an increase in uncertainty by a factor of ~1000, and a decrease in reliability by ~5%, on average. Using “expert-selected” surrogates ( n = 3) instead of “global” surrogates ( n = 25) for qNTA yielded improvements in predictive accuracy (by ~1.5×) and uncertainty (by ~70×) but at the cost of further-reduced reliability (by ~5%). Overall, our results illustrate the utility of qNTA approaches for a subclass of emerging contaminants and present a framework on which to develop new approaches for more complex use cases. Graphical Abstract

Pu, Shirley (ORCID:0000000201223797)↗

Characterization of the biofilm landscape of Bacillus subtilis by spatial microproteomics

Bulk proteomics has been demonstrated to differentiate subpopulations within bacterial colonies, yet advanced analyses by mass spectrometry imaging (MSI) hold even greater promise for the future. This technology can enable high-throughput spatial phenotyping that can reshape biological discovery by providing visualization of components of various biomolecular mechanisms. With high mass resolving power and high spatial resolution analyses being routine, we can confidently enable intact protein imaging directly from samples with minimal preparation. Pairing those analyses with bulk experimental libraries can provide high confidence in annotations of post-translational modifications (PTMs) and truncations. Revealing PTM localization within the samples unlocks a direct window into unknown biology at the microscale. However, top-down proteomics (TDP) is not commonplace for microbial species, largely due to challenges in identifying detected peptides and proteins; considering the theoretical proteome of even the well-studied model bacterium Bacillus subtilis was only partially mapped recently. With little still known about the form and function of many of these proteins – let alone proteoforms, where PTMs and truncations of the same protein may possess unique physiological roles – there is a wealth of work to be done. Here we jointly apply TDP and MSI to describe the microscale spatial proteomic landscape within B. subtilis and further demonstrate the feasibility of detecting differentiated subpopulations through proteoforms across the biofilm landscape.

bacterial biofilms↗

Representative Phenomena of Cyclic Turbulent Combustion in High-Pressure Fuel Sprays

Abstract Cyclic variations in conventional diesel combustion engines can lead to large differences in engine out emissions even at steady operation. This study uses an optically accessible constant-pressure flow chamber to acquire fuel injections in quick succession to analyze mixing, auto-ignition, and combustion of diesel-surrogate n-heptane using multiple high-speed optical diagnostics. Prior studies have utilized fewer injections and/or they rely on analysis of ensemble average behavior. These approaches do not yield information on injection-to-injection variation or provide confidence in utilizing individual injection measurements for high-fidelity computational fluid dynamics(CFD) model validation. In this study, a large set of 500 injections is used to obtain global parameters including liquid length, vapor penetration length, ignition delay time, and lift-off length. Results for multiple injections are presented to illustrate large injection to injection variations. Potential sources for these variations are analyzed to conclude localized, small scale turbulence and rate of injection variations as the likely sources. Then, a statistical method based on z-scores is proposed and implemented to identify instantaneous injections that best represent the bulk data-set of jet boundaries measured independently by three different diagnostics. This synthesis of statistics-guided screening of data set and ensemble-average analysis offers higher confidence for CFD model validation relying upon both a representative single and average injection results.

42 ENGINEERING↗

Radiation effects on atherosclerosis in atomic bomb survivors: a cross-sectional study using structural equation modeling

Past reports indicated that total-body irradiation at low to moderate doses could be responsible for cardiovascular disease risks, but the mechanism remains unclear. The purpose of this study was to investigate the association between radiation exposure and atherosclerosis, an underlying pathology of cardiovascular diseases, in the Japanese atomic bomb survivors. We performed a cross-sectional study measuring 14 clinical-physiological atherosclerosis indicators during clinical exams from 2010 to 2014 in 3274 participants of the Adult Health Study cohort. Multivariable analyses were performed by using a structural equation model with latent factors representing underlying atherosclerotic pathologies: (1) arterial stiffness, (2) calcification, and (3) plaque as measured with indicators chosen a priori on the basis of clinical-physiological knowledge. Radiation was linearly associated with calcification (standardized coefficient per Gy 0.15, 95 % confidence interval: CI [0.070, 0.23]) and plaque (0.11, 95 % CI [0.029, 0.20]), small associations that were comparable to about 2 years of aging per Gy of radiation exposure, but not with arterial stiffness (0.036, 95 % CI [-0.025, 0.095]). The model fitted better and had narrower confidence intervals than separate ordinary regression models explaining individual indicators independently. The associations were less evident when the dose range was restricted to a maximum of 2 or 1 Gy. By combining individual clinical-physiological indicators that are correlated because of common, underlying atherosclerotic pathologies, we found a small, but significant association of radiation with atherosclerosis.

59 BASIC BIOLOGICAL SCIENCES↗

Super Resolution Digital Image Correlation (SR-DIC): an Alternative to Image Stitching at High Magnifications

Abstract Background High-resolution Digital Image Correlation (DIC) measurements have previously been produced by stitching of neighboring images, which often requires short working distances. Separately, the image processing community has developed super resolution (SR) imaging techniques, which improve resolution by combining multiple overlapping images. Objective This work investigates the novel pairing of super resolution with digital image correlation, as an alternative method to produce high-resolution full-field strain measurements. Methods First, an image reconstruction test is performed, comparing the ability of three previously published SR algorithms to replicate a high-resolution image. Second, an applied translation is compared against DIC measurement using both low- and super-resolution images. Third, a ring sample is mechanically deformed and DIC strain measurements from low- and super-resolution images are compared. Results SR measurements show improvements compared to low-resolution images, although they do not perfectly replicate the high-resolution image. SR-DIC demonstrates reduced error and improved confidence in measuring rigid body translation when compared to low resolution alternatives, and it also shows improvement in spatial resolution for strain measurements of ring deformation. Conclusions Super resolution imaging can be effectively paired with Digital Image Correlation, offering improved spatial resolution, reduced error, and increased measurement confidence.

Hansen, R. S.↗