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Rapid insertion of bismuth radioactive isotopes into texaphyrin in aqueous media

Radioisotopes 213 Bi and 207 Bi were successfully inserted into a water-soluble and tumor-targeting texaphyrin ligand. The reaction with 207 Bi(OAc) 3 proceeds in about 15 min in aqueous media without the use of any organic base. The Bi(III) texaphyrin complex formed (3) is stable in aqueous media even in the presence of an excess of competitive chelators (EDTA or citric acid), as well as in human blood plasma. Finally, these results validate texaphyrins as potential candidates for coordinating bismuth radionuclides and set the stage for their use in targeted alpha therapy (TAT).

38 RADIATION CHEMISTRY, RADIOCHEMISTRY, AND NUCLEA↗

Initial dynamic photoactive materials testing of an atmospheric chamber intended for radioactive and hazardous gases

Radioisotopes and hazardous gases can have undetermined environmental pathways. Researchers at Pacific Northwest National Laboratory constructed a chamber that complies with the requirements needed for an atmospheric reaction platform and the safety principles of interacting with hazardous dispersible sources to enable the environmental testing of these gases. Initial dynamic testing showed inter-chamber mixing completed from minutes to 1.5 hours. The photooxidation of butyl iodine showed the presence of signals from reaction products, and intermediaries for up to 50 hours. Current detection limits of the chamber and analytical collection and testing approach were shown to be in the single-digit parts per billion levels. In conclusion, the comparisons between the measured oxidation trends and literature show the utility of performing laboratory experiments to validate the results of modeling for larger-scale scenarios.

54 ENVIRONMENTAL SCIENCES↗

Some Logistical Considerations in Designing a System of Deep Boreholes for Disposal of High-Level Radioactive Waste

Deep boreholes could be a relatively inexpensive, safe, and rapidly deployable strategy for disposing Americaś nuclear waste. To study this approach, Sandia invested in a three year LDRD project entitled “Radionuclide Transport from Deep Boreholes.” In the first two years, the borehole reference design and backfill analysis were completed and the supporting modeling of borehole temperature and fluid transport profiles were done. In the third year, some of the logistics of implementing a deep borehole waste disposal system were considered. This report describes what was learned in the third year of the study and draws some conclusions about the potential bottlenecks of system implementation.

Gray, Genetha Anne↗

DUSEL R&D: BetaCage: A Screener of Ultra-Low-Level Radioactive Surface Contamination (Final Report)

The eventual full-size, radiopure BetaCage will be a low-background, atmospheric-pressure neon drift chamber with unprecedented sensitivity to emitters of low-energy electrons and alpha particles. We expect that the prototype BetaCage already developed will be an excellent screener of alpha particles. Both the prototype and final BetaCage will provide new infrastructure for rare-event science.

46 INSTRUMENTATION RELATED TO NUCLEAR SCIENCE AND ↗

Definition of "Small Gram Quantity Contents" for Type B Radioactive Material Transportation Packages: Activity-Based Content Limitations, Rev. 1

The results presented are a compendium of allowable masses (and activities) of a variety of different isotopes ( with varying impurity levels of beryllium in some of the actinide isotopes) that, when loaded in an unshielded packaging, do not result in an external dose rate on the surface of the package that exceeds 190 mrem/hr.

11 NUCLEAR FUEL CYCLE AND FUEL MATERIALS↗

Development of Innovative Radioactive Isotope Production Techniques at the Pennsylvania State University Radiation Science and Engineering Center

The Penn State Breazeale Nuclear Reactor (PSBR) at the Radiation Science and Engineering Center (RSEC) has produced radioisotopes for research and commercial purposes since 1956. With the rebirth of the radiochemistry education and research program at the RSEC, the Center stands poised to produce a variety of radioisotopes for research and industrial work that is in line with the mission of the DOE Office of Science, Office of Nuclear Physics, Isotope Development and Production Research and Application Program. The RSEC received funding from the Office of Science in 2010 to improve production techniques and develop new capabilities. Under this program, we improved our existing techniques to provide four radioisotopes (Mn-56, Br-82, Na-24, and Ar-41) to researchers and industry in a safe and efficient manner. The RSEC is also working to develop new innovative techniques to provide isotopes in short supply to researchers and others in the scientific community, specifically Cu-64 and Cu-67. Improving our existing radioisotopes production techniques and investigating new and innovative methods are two of the main initiatives of the radiochemistry research program at the RSEC.

07 ISOTOPE AND RADIATION SOURCES↗