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At least 1,423 records · Page 79

Techniques used for the analysis of oculometer eye-scanning data obtained from an air traffic control display

The methodology and techniques used to collect and analyze look-point position data from a real-time ATC display-format comparison experiment are documented. That study compared the delivery precision and controller workload of three final approach spacing aid display formats. Using an oculometer, controller lookpoint position data were collected, associated with gaze objects (e.g., moving aircraft) on the ATC display, and analyzed to determine eye-scan behavior. The equipment involved and algorithms for saving, synchronizing with the ATC simulation output, and filtering the data are described. Target (gaze object) and cross-check scanning identification algorithms are also presented. Data tables are provided of total dwell times, average dwell times, and cross-check scans. Flow charts, block diagrams, file record descriptors, and source code are included. The techniques and data presented are intended to benefit researchers in other studies that incorporate non-stationary gaze objects and oculometer equipment.

Crawford, Daniel J.↗

Thermographic Nondestructive Evaluation of the Space Shuttle Main Engine Nozzle

The methods and results presented in this summary address the thermographic identification of interstitial leaks in the Space Shuttle Main Engine nozzles. A highly sensitive digital infrared camera is used to record the minute cooling effects associated with a leak source, such as a crack or pinhole, hidden within the nozzle wall by observing the inner "hot wall" surface as the nozzle is pressurized. These images are enhanced by digitally subtracting a thermal reference image taken before pressurization, greatly diminishing background noise. The method provides a nonintrusive way of localizing the tube that is leaking and the exact leak source position to within a very small axial distance. Many of the factors that influence the inspectability of the nozzle are addressed; including pressure rate, peak pressure, gas type, ambient temperature and surface preparation.

Walker, James L.↗

Thermographic/Nondestructive Evaluation of the Space Shuttle Main Engine Nozzle

The methods and results presented in this summary address the thermographic identification of interstitial leaks in the Space Shuttle Main Engine nozzles. A highly sensitive digital infrared camera is used to record the minute cooling effects associated with a leak source, such as a crack or pinhole, hidden within the nozzle wall by observing the inner 'hot wall' surface as the nozzle is pressurized. These images are enhanced by digitally subtracting a thermal reference image taken before pressurization, greatly diminishing background noise. The method provides a nonintrusive way of localizing the tube that is leaking and the exact leak source position to within a very small axial distance. Many of the factors that influence the inspectability of the nozzle are addressed; including pressure rate, peak pressure, gas type, ambient temperature and surface preparation.

Walker, J. L.↗

Surface Displacement of the May 17, 1993 Eureka Valley, California, Earthquake

Satellite synthetic aperture radar (SAR) interferometry shows that the magnitude 6.1 Eureka Valley earthquake of 17 May 1993 produced an elongated subsidence basin oriented north-northwest, parallel to the trend defined by the aftershock distribution, whereas the source mechanism of the earthquake implies a north-northeast-striking normal fault. The ±3-millimeter accuracy of the radar-observed displacement map over short spatial scales allowed identification of the main surface rupture associated with the event. These observations suggest that the rupture began at depth and propagated diagonally upward and southward on a west-dipping, north-northeast fault plane, reactivating the largest escarpment in the Saline Range.

Gilles Peltzer↗

Big Bend Ecological Forecasting: Integrating Earth Observations Into Invasive Species Management Decisions in Big Bend National Park in Texas

Located in Brewster County Texas, U.S., along the Texas-Mexico border, Big Bend National Park is 3,243 square kilometers of desert, mountains, and rivers. NASA’s MSFC Spring 2024 DEVELOP Team partnered with the National Park Service (NPS), to address the environmental concern of perineal invasive grasses in Big Bend National Park. Buffelgrass (Cenchrus ciliaris), introduced to the park in the 1940’s, poses an ongoing threat, and causes habitat destruction for many of the park’s native ecosystems. Buffelgrass amplifies fire risk in the park, aids in the destruction of historic structures, and alters stream channels. To address the rising concern of Buffelgrass presence, unique advanced spatial technique applications were necessary to construct a habitat suitability model and perform a comprehensive fire risk assessment. A habitat suitability model was developed considering climate, vegetation, and phenological variables, in addition to physical and topographical variables. Subsequently, a fire risk model was developed, taking into account fire history data, accessibility factors, climate trends and predictions, along with developed areas. Multi-Source Land Surface Phenology (LSP) Sentinel-2 and Landsat 8 Operational Land Imager (OLI) imagery were used to predict Buffelgrass hotspot locations throughout the park. These analyses allowed the identification of optimal Buffelgrass habitat and hotspot locations, as well as park zones that reflect the greatest risk for future Buffelgrass invasion and fire risk. The collective results of the habitat suitability model, fire risk assessment, and Buffelgrass hot spot identification will allow the NPS to facilitate efficient mitigation measures and management strategies, and improved resource allocation where it’s most needed.

remote sensing↗

Nuclear Interdiction Through Relocatable Detectors

The NNSA Office of Nuclear Smuggling Detection and Deterrence (NSDD) has investigated a set of minimal-infrastructure radiation detection systems as alternatives to fixed Radiation Portal Monitors (RPMs) for nuclear interdiction applications. These versatile and relocatable systems can improve nuclear security in missions or locations that do not warrant or support a standard fixed radiation detection system. Over 2019, a variety of relocatable detectors were characterized at the Interdiction Technologies Integration Laboratory at Pacific Northwest National Laboratory (PNNL). Evaluated detectors were diverse in their size and capabilities, ranging from backpack-sized systems to lane-spanning cargo scanning portals. Both spectroscopic and non-spectroscopic pedestrian and vehicle detection systems were characterized against uranium and plutonium sources. Signatures from the sources were modulated by both shielding and distance to quantify the performance of the relocatable systems as signal strength was decreased. Findings showed that relocatable spectroscopic detectors with isotope identification capabilities could reduce nuisance alarm rates compared to conventional fixed installation, gross-counting, radiation portal monitors. In vehicle scanning applications, detection ability generally trended with detection volume, regardless of spectral capability. In pedestrian scanning applications, several smaller backpack-sized detector systems were found to be more sensitive to detecting material than pedestrian portal monitors. The results of this characterization effort have helped inform the deployment of versatile equipment to improve nuclear security missions.

relocatable detectors, Nuclear Security↗

Identification of Presolar Grains in Quick Look Samples of Asteroid Bennu Returned By the OSIRIS-REx Mission

The OSIRIS-REx spacecraft returned regolith sample from the B-type asteroid Bennu on September 24, 2023. The first samples to be analyzed, termed the Quick Look samples, are comprised of material collected from the avionics deck of the OSIRIS-REx sample canister. Initial mineralogical analysis of the Quick Look sample revealed a diversity of components, including hydrated and anhydrous silicates, sulfides, magnetite, phosphates, and abundant organic matter. Each constituent has their own origin and history, and their study can inform us of the history of Bennu and its parent asteroid. The analysis plan for asteroid Bennu samples is guided by hypotheses that address specific periods of Bennu’s history, from the pre-accretionary epoch to the OSIRIS-REx epoch. The pre-accretionary epoch studies aim to characterize materials that predate the formation of the solar system. One hypothesis that falls under this epoch is that Bennu contains presolar materials derived from diverse sources. These presolar materials include stardust grains that condensed from the outflows of evolved stars or the ejecta of novae and supernovae (SN), as well as organic matter that formed in the interstellar medium. Here we report the identification of C-rich presolar stardust grains in the Bennu Quick Look sample. Isotopically anomalous organic matter in this sample is reported in.

A N Nguyen↗

Spitzer/infrared spectrograph investigation of mipsgal 24 μm compact bubbles: low-resolution observations

We present Spitzer/InfraRed Spectrograph (IRS) low-resolution observations of 11 compact circumstellar bubbles from the MIPSGAL 24 μm Galactic plane survey. We find that this set of MIPSGAL bubbles (MBs) is divided into two categories and that this distinction correlates with the morphologies of the MBs in the mid-infrared (IR). The four MBs with central sources in the mid-IR exhibit dust-rich, low-excitation spectra, and their 24 μm emission is accounted for by the dust continuum. The seven MBs without central sources in the mid-IR have spectra dominated by high-excitation gas lines (e.g., [O IV] 26.0 μm, [Ne V] 14.3 and 24.3 μm, and [Ne III] 15.5 μm), and the [O IV] line accounts for 50% to almost 100% of the 24 μm emission in five of them. In the dust-poor MBs, the [Ne V] and [Ne III] line ratios correspond to high-excitation conditions. Based on comparisons with published IRS spectra, we suggest that the dust-poor MBs are highly excited planetary nebulae (PNs) with peculiar white dwarfs (e.g., Wolf-Rayet [WR] and novae) at their centers. The central stars of the four dust-rich MBs are all massive star candidates. Dust temperatures range from 40 to 100 K in the outer shells. We constrain the extinction along the lines of sight from the IRS spectra. We then derive distance, dust masses, and dust production rate estimates for these objects. These estimates are all consistent with the nature of the central stars. We summarize the identifications of MBs made to date and discuss the correlation between their mid-IR morphologies and natures. Candidate Be/B[e]/luminous blue variable and WR stars are mainly 'rings' with mid-IR central sources, whereas PNs are mostly 'disks' without mid-IR central sources. Therefore we expect that most of the 300 remaining unidentified MBs will be classified as PNs.

79 ASTRONOMY AND ASTROPHYSICS↗

Sensitivity of the Cherenkov Telescope Array to spectral signatures of hadronic PeVatrons with application to Galactic Supernova Remnants

The local Cosmic Ray (CR) energy spectrum exhibits a spectral softening at energies around 3 PeV. Sources which are capable of accelerating hadrons to such energies are called hadronic PeVatrons. However, hadronic PeVatrons have not yet been firmly identified within the Galaxy. Several source classes, including Galactic Supernova Remnants (SNRs), have been proposed as PeVatron candidates. The potential to search for hadronic PeVatrons with the Cherenkov Telescope Array (CTA) is assessed. The focus is on the usage of very high energy γ-ray spectral signatures for the identification of PeVatrons. Assuming that SNRs can accelerate CRs up to knee energies, the number of Galactic SNRs which can be identified as PeVatrons with CTA is estimated within a model for the evolution of SNRs. Additionally, the potential of a follow-up observation strategy under moonlight conditions for PeVatron searches is investigated. Statistical methods for the identification of PeVatrons are introduced, and realistic Monte-Carlo simulations of the response of the CTA observatory to the emission spectra from hadronic PeVatrons are performed. Based on simulations of a simplified model for the evolution for SNRs, the detection of a γ-ray signal from in average 9 Galactic PeVatron SNRs is expected to result from the scan of the Galactic plane with CTA after 10 h of exposure. Finally, CTA is also shown to have excellent potential to confirm these sources as PeVatrons in deep observations with $\mathscr{O}$ (100) hours of exposure per source.

79 ASTRONOMY AND ASTROPHYSICS↗

Identification of Safety Metrics for Airport Surface Operations

A large fraction of safety incidents occurs on the ground during airport surface operations. Although these incidents are mostly non-fatal with a few exceptions, they are high profile incidents that remain a source of concern for the National Transportation Safety Board (NTSB), the Federal Aviation Administration (FAA), major airlines, and other stakeholders of the National Airspace System (NAS). These incidents have historically been mitigated by implementing changes to regulations, policies, and procedures over time. This approach has minimized but not eliminated the risk of occurrences. It is thus important to develop integrated techniques to assess, model, and prevent these incidents by analyzing the risk and likelihood of occurrence and communicating results of the analysis to decision-making personnel who can mitigate and prevent incidents in real time. The research presented in this report builds on prior work of researchers at the NASA Ames Research Center who developed an automated framework, Real-Time Safety Monitoring (RTSM), to enable monitoring and prediction of the safety of the NAS. In the RTSM framework, hazards to flight are translated to safety metrics such as wake vortex encounters or loss of separation, that can be modeled and analyzed offline and also predicted and monitored in real time (online). The intent of this report is to integrate predictable incidents that occur during surface and ground operations into the safety portfolio of the RTSM project by (i) identifying suitable information sources from which ground incidents can be studied, (ii) developing safety metrics correlated with surface operations, and (iii) recommending suitable data sources that can be quantified and used for the computation of pertinent safety metrics.

ground operations↗

Identification of Safety Metrics for Airport Surface Operations

A large fraction of safety incidents occurs on the ground during airport surface operations. Although these incidents are mostly non-fatal with a few exceptions, they are high profile incidents that remain a source of concern for the National Transportation Safety Board (NTSB), the Federal Aviation Administration (FAA), major airlines, and other stakeholders of the National Airspace System (NAS). These incidents have historically been mitigated by implementing changes to regulations, policies, and procedures over time. This approach has minimized but not eliminated the risk of occurrence of safety incidents. It is thus important to develop integrated techniques to assess, model, and prevent these incidents by analyzing the risk and likelihood of occurrence and communicating results of the analysis to decision-making personnel who can mitigate and prevent incidents in real time. The work presented in this paper builds on a previously developed architecture for safety, Real-Time Safety Monitoring (RTSM), to enable monitoring and prediction of the safety of the NAS. In the RTSM framework, hazards to flight are translated to safety metrics such as wake vortex encounters or loss of separation, that can be modeled and analyzed offline and also predicted and monitored in real time (online). The intent of this paper is to integrate predictable incidents that occur during surface and ground operations into the safety portfolio of the RTSM project by (i) identifying suitable information sources from which ground incidents can be studied, (ii) developing safety metrics correlated with surface operations, and (iii) recommending suitable data sources that can be quantified and used for the computation of pertinent safety metrics.

safety↗

Genetically engineered mouse models of esophageal cancer

Esophageal cancer is the most common cause of cancer-related death worldwide with a diverse geographical distribution, poor prognosis, and diagnosis in advanced stages of the disease. Identification of the mechanisms involved in esophageal cancer development is evaluative to improve outcomes for patients. Genetically engineered mouse models (GEMMs) of cancer provide the physiologic, molecular, and histologic features of the human tumors to determine the pathogenesis and treatments for cancer, hence exhibiting a source of tremendous potential for oncology research. The advancement of cancer modeling in mice has improved to the extent that researchers can observe and manipulate the disease process in a specific manner. Despite the significant differences between mice and humans, mice can be great models for human oncology researches due to similarities between them at the molecular and physiological levels. Due to most of the existing esophageal cancer GEMMs do not propose an ideal system for pathogenesis of the disease, genetic risks, and microenvironment exposure, so identification of challenges in GEM modeling and well-developed technologies are required to obtain the most value for patients. In this review, we describe the biology of human and mouse, followed by the exciting esophageal cancer mouse models with a discussion of applicability and challenges of these models for generating new GEMMs in future studies.

60 APPLIED LIFE SCIENCES↗

A genome-wide analysis of the flax (Linum usitatissimum L.) dirigent protein family: from gene identification and evolution to differential regulation

Identification of DIR encoding genes in flax genome. Analysis of phylogeny, gene/protein structures and evolution. Identification of new conserved motifs linked to biochemical functions. Investigation of spatio-temporal gene expression and response to stress. Dirigent proteins (DIRs) were discovered during 8-8' lignan biosynthesis studies, through identification of stereoselective coupling to afford either (+)- or (-)-pinoresinols from E-coniferyl alcohol. DIRs are also involved or potentially involved in terpenoid, allyl/propenyl phenol lignan, pterocarpan and lignin biosynthesis. DIRs have very large multigene families in different vascular plants including flax, with most still of unknown function. DIR studies typically focus on a small subset of genes and identification of biochemical/physiological functions. Herein, a genome-wide analysis and characterization of the predicted flax DIR 44-membered multigene family was performed, this species being a rich natural grain source of 8-8' linked secoisolariciresinol-derived lignan oligomers. All predicted DIR sequences, including their promoters, were analyzed together with their public gene expression datasets. Expression patterns of selected DIRs were examined using qPCR, as well as through clustering analysis of DIR gene expression. These analyses further implicated roles for specific DIRs in (-)-pinoresinol formation in seed-coats, as well as (+)-pinoresinol in vegetative organs and/or specific responses to stress. Phylogeny and gene expression analysis segregated flax DIRs into six distinct clusters with new cluster-specific motifs identified. We propose that these findings can serve as a foundation to further systematically determine functions of DIRs, i.e. other than those already known in lignan biosynthesis in flax and other species. Given the differential expression profiles and inducibility of the flax DIR family, we provisionally propose that some DIR genes of unknown function could be involved in different aspects of secondary cell wall biosynthesis and plant defense.

dirigent protein↗

Computational fluid dynamics analysis of char conversion in Sandia’s pressurized entrained flow reactor

Design and analysis of practical reactors utilizing solid feedstocks rely on reaction rate parameters that are typically generated in lab-scale reactors. Evaluation of the reaction rate information often relies on assumptions of uniform temperature, velocity, and species distributions in the reactor, in lieu of detailed measurements that provide local information. This assumption might be a source of substantial error, since reactor designs can impose significant inhomogeneities, leading to data misinterpretation. Spatially resolved reactor simulations help understand the key processes within the reactor and support the identification of severe variations of temperature, velocity, and species distributions. In this work, Sandia’s pressurized entrained flow reactor is modeled to identify inhomogeneities in the reaction zone. Tracer particles are tracked through the reactor to estimate the residence times and burnout ratio of introduced coal char particles in gasifying environments. The results reveal a complex mixing environment for the cool gas and particles entering the reactor along the centerline and the main high-speed hot gas reactor flow. Furthermore, the computational fluid dynamics (CFD) results show that flow asymmetries are introduced through the use of a horizontal gas pre-heating section that connects to the vertical reactor tube. Computed particle temperatures and residence times in the reactor differ substantially from the idealized plug flow conditions typically evoked in interpreting experimental measurements. Furthermore, experimental measurements and CFD analysis of heat flow through porous refractory insulation suggest that for the investigated conditions (1350 °C, <20 atm), the thermal conductivity of the insulation does not increase substantially with increasing pressure.

47 OTHER INSTRUMENTATION↗

Observational results of a multi-telescope campaign in search of interstellar urea [(NH{sub 2}){sub 2}CO]

In this paper, we present the results of an observational search for gas phase urea [(NH{sub 2}){sub 2}CO] observed toward the Sgr B2(N-LMH) region. We show data covering urea transitions from ∼100 GHz to 250 GHz from five different observational facilities: the Berkeley-Illinois-Maryland-Association (BIMA) Array, the Combined Array for Research in Millimeter-wave Astronomy (CARMA), the NRAO 12 m telescope, the IRAM 30 m telescope, and the Swedish-ESO Submillimeter Telescope (SEST). The results show that the features ascribed to urea can be reproduced across the entire observed bandwidth and all facilities by best-fit column density, temperature, and source size parameters which vary by less than a factor of two between observations merely by adjusting for telescope-specific parameters. Interferometric observations show that the emission arising from these transitions is cospatial and compact, consistent with the derived source sizes and emission from a single species. Despite this evidence, the spectral complexity of both (NH{sub 2}){sub 2}CO and of Sgr B2(N) makes the definitive identification of this molecule challenging. We present observational spectra, laboratory data, and models, and discuss our results in the context of a possible molecular detection of urea.

79 ASTRONOMY AND ASTROPHYSICS↗

Characterization of a novel polyextremotolerant fungus, Exophiala viscosa , with insights into its melanin regulation and ecological niche

Black yeasts are polyextremotolerant fungi that contain high amounts of melanin in their cell wall and maintain a primary yeast form. These fungi grow in xeric, nutrient depletes environments which implies that they require highly flexible metabolisms and have been suggested to contain the ability to form lichen-like mutualisms with nearby algae and bacteria. However, the exact ecological niche and interactions between these fungi and their surrounding community are not well understood. We have isolated 2 novel black yeasts from the genus Exophiala that were recovered from dryland biological soil crusts. Despite notable differences in colony and cellular morphology, both fungi appear to be members of the same species, which has been named Exophiala viscosa (i.e. E. viscosa JF 03-3 Goopy and E. viscosa JF 03-4F Slimy). A combination of whole genome sequencing, phenotypic experiments, and melanin regulation experiments have been performed on these isolates to fully characterize these fungi and help decipher their fundamental niche within the biological soil crust consortium. Our results reveal that E. viscosa is capable of utilizing a wide variety of carbon and nitrogen sources potentially derived from symbiotic microbes, can withstand many forms of abiotic stresses, and excretes melanin which can potentially provide ultraviolet resistance to the biological soil crust community. Besides the identification of a novel species within the genus Exophiala, our study also provides new insight into the regulation of melanin production in polyextremotolerant fungi.

60 APPLIED LIFE SCIENCES↗

Robocrystallographer: automated crystal structure text descriptions and analysis

Our ability to describe crystal structure features is of crucial importance when attempting to understand structure–property relationships in the solid state. Here, the authors introduce robocrystallographer, an open-source toolkit for analyzing crystal structures. This package combines new and existing open-source analysis tools to provide structural information, including the local coordination and polyhedral type, polyhedral connectivity, octahedral tilt angles, component-dimensionality, and molecule-within-crystal and fuzzy prototype identification. Using this information, robocrystallographer can generate text-based descriptions of crystal structures that resemble descriptions written by human crystallographers. The authors use robocrystallographer to investigate the dimensionalities of all compounds in the Materials Project database and highlight its potential in machine learning studies.

36 MATERIALS SCIENCE↗

Multivariate Statistical Analysis of Orthogonal Mass Spectral Data for the Identification of Chemical Attribution Signatures of 3-Methylfentanyl

Critical to many modern forensic investigations is the chemical attribution of the origin of an illegal drug. This process greatly relies on identification of compounds indicative of its clandestine or commercial production. The results of these studies can yield detailed information on method of manufacture, sophistication of the synthesis operation, starting material source, and final product. In the present work, chemical attribution signatures (CAS) associated with the synthesis of the analgesic 3- methylfentanyl, N-(3-methyl-1-phenethylpiperidin-4-yl)-N-phenylpropanamide, were investigated. Six synthesis methods were studied in an effort to identify and classify route-specific signatures. These methods were chosen to minimize the use of scheduled precursors, complicated laboratory equipment, number of overall steps, and demanding reaction conditions. Using gas and liquid chromatographies combined with mass spectrometric methods (GC-QTOF and LC-QTOF) in conjunction with inductivelycoupled plasma mass spectrometry (ICP-MS), over 240 distinct compounds and elements were monitored. As seen in our previous work with CAS of fentanyl synthesis the complexity of the resultant data matrix necessitated the use of multivariate statistical analysis. Using partial least squares discriminant analysis (PLS-DA), 62 statistically significant, route-specific CAS were identified. Statistical classification models using a variety of machine learning techniques were then developed with the ability to predict the method of 3-methylfentanyl synthesis from three blind crude samples generated by synthetic chemists without prior experience with these methods.

37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CH↗