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At least 1,423 records · Page 79
All sourcesNASA NTRSDOE OSTI
NASA NTRS2007

Build-Up Approach to Updating the Mock Quiet Spike Beam Model

When a new aircraft is designed or a modification is done to an existing aircraft, the aeroelastic properties of the aircraft should be examined to ensure the aircraft is flight worthy. Evaluating the aeroelastic properties of a new or modified aircraft can include performing a variety of analyses, such as modal and flutter analyses. In order to produce accurate results from these analyses, it is imperative to work with finite element models (FEM) that have been validated by or correlated to ground vibration test (GVT) data, Updating an analytical model using measured data is a challenge in the area of structural dynamics. The analytical model update process encompasses a series of optimizations that match analytical frequencies and mode shapes to the measured modal characteristics of structure. In the past, the method used to update a model to test data was "trial and error." This is an inefficient method - running a modal analysis, comparing the analytical results to the GVT data, manually modifying one or more structural parameters (mass, CG, inertia, area, etc.), rerunning the analysis, and comparing the new analytical modal characteristics to the GVT modal data. If the match is close enough (close enough defined by analyst's updating requirements), then the updating process is completed. If the match does not meet updating-requirements, then the parameters are changed again and the process is repeated. Clearly, this manual optimization process is highly inefficient for large FEM's and/or a large number of structural parameters. NASA Dryden Flight Research Center (DFRC) has developed, in-house, a Mode Matching Code that automates the above-mentioned optimization process, DFRC's in-house Mode Matching Code reads mode shapes and frequencies acquired from GVT to create the target model. It also reads the current analytical model, as we11 as the design variables and their upper and lower limits. It performs a modal analysis on this model and modifies it to create an updated model that has similar mode shapes and frequencies as those of the target model. The Mode Matching Code output frequencies and modal assurance criteria (MAC) values that allow for the quantified comparison of the updated model versus the target model. A recent application of this code is the F453 supersonic flight testing platform, NASA DFRC possesses a modified F-15B that is used as a test bed aircraft for supersonic flight experiments. Traditionally, the finite element model of the test article is generated. A GVT is done on the test article ta validate and update its FEM. This FEM is then mated to the F-15B model, which was correlated to GVT data in fall of 2004, A GVT is conducted with the test article mated to the aircraft, and this mated F-15B/ test article FEM is correlated to this final GVT.

Herrera, Claudia Y.↗
DOE OSTI2017

NXIS - Well integrity inspection in unconventional gas wells

The objective of this project is to advance the state-of-the-art and to develop an integrity inspection system capable of detecting physical flaws in the wellbore structure of conventional and unconventional hydrocarbon producing wells. Measuring the integrity of multiple wellbore casings and cement annuli for onshore and offshore wells remains a challenging task. We propose a multi-modality inspection system composed of neutron and X(gamma)-ray imaging modalities (nXis) to address the above challenge. The functional principle of this wellbore integrity inspection system is the combination of high-energy modalities, such as X(gamma)-ray and neutron backscatter imaging, with conventional low-energy modalities, such as electromagnetic or ultrasound imaging techniques. By combining multiple sensing modalities into one sensing system and by fusing data between modalities, one can gather more information about the integrity of the wellbore structure compared to simply using multiple sensors individually. Imaging prototypes for gamma, neutron, and electromagnetics were designed, manufactured, and tested at GE Global Research and Starfire Industries. Wellbore phantoms with engineered defects were manufactured and the performance of the developed wellbore integrity inspection tool prototypes was evaluated in a test pit test at an industrial GE Oil & Gas facility. Data analysis and fusion between various inspection techniques show enhanced defect detectability. These exciting results were presented at various technical conferences and discussed with operators in the oil & gas industry. Great interest from oil operators lead to discussions about joint industrial partnerships to move the developed technology from the prototype phase to the product phase.

46 INSTRUMENTATION RELATED TO NUCLEAR SCIENCE AND ↗
DOE OSTI2012

Impact of Computed Tomography Image Quality on Image-Guided Radiation Therapy Based on Soft Tissue Registration

Purpose: In image-guided radiation therapy (IGRT), different computed tomography (CT) modalities with varying image quality are being used to correct for interfractional variations in patient set-up and anatomy changes, thereby reducing clinical target volume to the planning target volume (CTV-to-PTV) margins. We explore how CT image quality affects patient repositioning and CTV-to-PTV margins in soft tissue registration-based IGRT for prostate cancer patients. Methods and Materials: Four CT-based IGRT modalities used for prostate RT were considered in this study: MV fan beam CT (MVFBCT) (Tomotherapy), MV cone beam CT (MVCBCT) (MVision; Siemens), kV fan beam CT (kVFBCT) (CTVision, Siemens), and kV cone beam CT (kVCBCT) (Synergy; Elekta). Daily shifts were determined by manual registration to achieve the best soft tissue agreement. Effect of image quality on patient repositioning was determined by statistical analysis of daily shifts for 136 patients (34 per modality). Inter- and intraobserver variability of soft tissue registration was evaluated based on the registration of a representative scan for each CT modality with its corresponding planning scan. Results: Superior image quality with the kVFBCT resulted in reduced uncertainty in soft tissue registration during IGRT compared with other image modalities for IGRT. The largest interobserver variations of soft tissue registration were 1.1 mm, 2.5 mm, 2.6 mm, and 3.2 mm for kVFBCT, kVCBCT, MVFBCT, and MVCBCT, respectively. Conclusions: Image quality adversely affects the reproducibility of soft tissue-based registration for IGRT and necessitates a careful consideration of residual uncertainties in determining different CTV-to-PTV margins for IGRT using different image modalities.

62 RADIOLOGY AND NUCLEAR MEDICINE↗
DOE OSTI2026

A comparative study of multimodal data fusion strategies for planetary spectroscopy

Integrating heterogeneous data sources can improve scientific inference when different modalities capture complementary information, but doing so is challenging in high-dimensional, small-sample settings. In spectroscopy for planetary exploration, Laser-Induced Breakdown Spectroscopy (LIBS), Raman Spectroscopy (Raman), Visible Infrared Spectroscopy (VISIR), and Mid-Infrared Spectroscopy (MIR) each examine different aspects of composition and mineralogy, raising fundamental questions about when and how data fusion improves predictive performance. Using a Mars-relevant set of geologic standards with measurements from all four modalities, we present a rigorous systematic evaluation of four data fusion strategies: low-level (data) fusion, mid-level (feature) fusion, high-level (decision) fusion, and residual-boosting (sequential) fusion. We assess performance in predicting oxide composition via nested cross-validation and corrected significance testing to evaluate whether data fusion improves upon single-modality baselines. We show that data fusion does not uniformly improve accuracy, and that observed gains are modest, oxide-dependent, and sensitive to modality and model structure. To move beyond aggregate accuracy metrics, we use model coefficients, permutation importance, and residual gain analysis to examine how the fusion models weight individual modalities and to identify patterns of apparent complementarity or redundancy. Though focused on spectroscopy for planetary exploration, our framework for data fusion evaluation and interpretation extends to other scientific domains with heterogeneous and scarce data and provides a principled approach evaluating data fusion strategies, interpreting modality contributions, and understanding tradeoffs among data fusion strategies.

97 MATHEMATICS AND COMPUTING↗
DOE OSTI2013

Brain metastases in women with epithelial ovarian cancer: multimodal treatment including surgery or gamma-knife radiation is associated with prolonged survival

Objective: To explore the impact of treatment modality on survival in patients with brain metastases from epithelial ovarian cancer. Methods: We conducted a retrospective review of cases of ovarian cancer with brain metastases treated at institutions in three countries (Canada, China, and India) and conducted a search for studies regarding brain metastases in ovarian cancer reporting survival related to treatment modality. Survival was analyzed according to treatment regimens involving (1) some form of surgical excision or gamma-knife radiation with or without other modalities, (2) other modalities without surgery or gamma-knife radiation, or (3) palliation only. Results: Twelve patients (mean age 56 years) with detailed treatment/outcome data were included; five were from China, four from Canada, and three from India. Median time from diagnosis of ovarian cancer to brain metastasis was 19 months (range 10 to 37 months), and overall median survival time from diagnosis of ovarian cancer was 38 months (13 to 82 months). Median survival time from diagnosis of brain metastasis was 17 months (1 to 45 months). Among patients who had multimodal treatment including gamma-knife radiotherapy or surgical excision, the median survival time after the identification of brain metastasis was 25.6 months, compared with 6.0 months in patients whose treatment did not include this type of focused localized modality (P = 0.006). Analysis of 20 studies also indicated that use of gamma-knife radiotherapy and excisional surgery in multi-modal treatment resulted in improved median survival interval (25 months vs. 6.0 months, P < 0.001). Conclusions: In the subset of patients with brain metastases from ovarian cancer, prolonged survival may result from use of multidisciplinary therapy, particularly if metastases are amenable to localized treatments such as gamma-knife radiotherapy and surgical excision. (author)

62 RADIOLOGY AND NUCLEAR MEDICINE↗
DOE OSTI2012

ULTRA-FAINT DWARF GALAXIES AS A TEST OF EARLY ENRICHMENT AND METALLICITY-DEPENDENT STAR FORMATION

The close relation of star formation with molecular gas indicated by observations and assumed in recent models implies that the efficiency with which galaxies convert their gas into stars depends on gas metallicity. This is because abundance of molecular hydrogen is sensitive to abundance of dust, which catalyzes formation of H{sub 2} and helps to shield it from dissociating radiation. In this study, we point out that in the absence of significant pre-enrichment by Population III stars forming out of zero metallicity gas, such H{sub 2}-based star formation is expected to leave an imprint in the form of bi-modality in the metallicity distribution among dwarf galaxies and in the metallicity distribution of stars within individual galaxies. The bi-modality arises because when gas metallicity (and dust abundance) is low, formation of molecular gas is inefficient, the gas consumption timescale is long, and star formation and metal enrichment proceed slowly. When metallicity reaches a critical threshold value star formation and enrichment accelerate, which leads to rapid increase in both stellar mass and metallicity of galaxies. We demonstrate this process both using a simple analytical model and full cosmological simulations. In contrast, the observed metallicity distributions of dwarf galaxies or stars within them are not bi-modal. We argue that this discrepancy points to substantial early stochastic pre-enrichment by Population III stars to levels Z {approx} 10{sup -2} Z{sub Sun} in dense, star-forming regions of early galaxies.

79 ASTRONOMY AND ASTROPHYSICS↗
DOE OSTI2013

Evaluation of the cone beam CT for internal target volume localization in lung stereotactic radiotherapy in comparison with 4D MIP images

Purpose: To investigate whether the three-dimensional cone-beam CT (CBCT) is clinically equivalent to the four-dimensional computed tomography (4DCT) maximum intensity projection (MIP) reconstructed images for internal target volume (ITV) localization in image-guided lung stereotactic radiotherapy.Methods: A ball-shaped polystyrene phantom with built-in cube, sphere, and cone of known volumes was attached to a motor-driven platform, which simulates a sinusoidal movement with changeable motion amplitude and frequency. Target motion was simulated in the patient in a superior-inferior (S-I) direction with three motion periods and 2 cm peak-to-peak amplitudes. The Varian onboard Exact-Arms kV CBCT system and the GE LightSpeed four-slice CT integrated with the respiratory-position-management 4DCT scanner were used to scan the moving phantom. MIP images were generated from the 4DCT images. The clinical equivalence of the two sets of images was evaluated by comparing the extreme locations of the moving objects along the motion direction, the centroid position of the ITV, and the ITV volumes that were contoured automatically by Velocity or calculated with an imaging gradient method. The authors compared the ITV volumes determined by the above methods with those theoretically predicted by taking into account the physical object dimensions and the motion amplitudes. The extreme locations were determined by the gradient method along the S-I axis through the center of the object. The centroid positions were determined by autocenter functions. The effect of motion period on the volume sizes was also studied.Results: It was found that the extreme locations of the objects determined from the two image modalities agreed with each other satisfactorily. They were not affected by the motion period. The average difference between the two modalities in the extreme locations was 0.68% for the cube, 1.35% for the sphere, and 0.5% for the cone, respectively. The maximum difference in the centroid position of the cylinder, sphere, and cone was less than 1.4 mm between the two modalities for all motion periods studied. For the ITV volume evaluation, the authors found that both MIP-based and CBCT-based ITVs increased with increases of motion period. Furthermore, the MIP-based ITV volumes were generally larger than those determined from the CBCT images, with the difference in autocontoured volumes being 2.57%, 1.66%, and 1.82% for the sphere, cylinder, and cone, respectively, while these differences increased to 9.57%, 3.52%, 8.71% for the above objects when the gradient method was used. The authors found that the autocontour method was accurate enough to predict the actual ITV values with the absolute differences less than 2.4% comparing to the theoretically predicted values.Conclusions: The extreme location and the centroid position of the objects agree with each other between the two image modalities when the breathing motion is sinusoidal. Although the ITV volumes delineated from both image modalities changed with the motion period, the differences in ITV between the two modalities were minimal when an optimized window level was used. The authors’ results suggest that CBCT and MIP images are equivalent in determining an ITV's position in the conditions studied. The CBCT is adequate in providing imaging-guidance for lung cancer treatment.

62 RADIOLOGY AND NUCLEAR MEDICINE↗
DOE OSTI2014

SU-E-P-10: Imaging in the Cardiac Catheterization Lab - Technologies and Clinical Applications

Purpose: Diagnosis and treatment of cardiovascular disease in the cardiac catheterization laboratory is often aided by a multitude of imaging technologies. The purpose of this work is to highlight the contributions to patient care offered by the various imaging systems used during cardiovascular interventional procedures. Methods: Imaging technologies used in the cardiac catheterization lab were characterized by their fundamental technology and by the clinical applications for which they are used. Whether the modality is external to the patient, intravascular, or intracavity was specified. Specific clinical procedures for which multiple modalities are routinely used will be highlighted. Results: X-ray imaging modalities include fluoroscopy/angiography and angiography CT. Ultrasound imaging is performed with external, trans-esophageal echocardiography (TEE), and intravascular (IVUS) transducers. Intravascular infrared optical coherence tomography (IVOCT) is used to assess vessel endothelium. Relatively large (>0.5 mm) anatomical structures are imaged with x-ray and ultrasound. IVUS and IVOCT provide high resolution images of vessel walls. Cardiac CT and MRI images are used to plan complex cardiovascular interventions. Advanced applications are used to spatially and temporally merge images from different technologies. Diagnosis and treatment of coronary artery disease frequently utilizes angiography and intra-vascular imaging, and treatment of complex structural heart conditions routinely includes use of multiple imaging modalities. Conclusion: There are several imaging modalities which are routinely used in the cardiac catheterization laboratory to diagnose and treat both coronary artery and structural heart disease. Multiple modalities are frequently used to enhance the quality and safety of procedures. The cardiac catheterization laboratory includes many opportunities for medical physicists to contribute substantially toward advancing patient care.

60 APPLIED LIFE SCIENCES↗
DOE OSTI2014

MO-G-9A-01: Imaging Refresher for Standard of Care Radiation Therapy

Imaging techniques and technology which were previously the domain of diagnostic medicine are becoming increasingly integrated and utilized in radiation therapy (RT) clinical practice. As such, there are a number of specific imaging topics that are highly applicable to modern radiation therapy physics. As imaging becomes more widely integrated into standard clinical radiation oncology practice, the impetus is on RT physicists to be informed and up-to-date on those imaging modalities relevant to the design and delivery of therapeutic radiation treatments. For example, knowing that, for a given situation, a fluid attenuated inversion recovery (FLAIR) image set is most likely what the physician would like to import and contour is helpful, but may not be sufficient to providing the best quality of care. Understanding the physics of how that pulse sequence works and why it is used could help assess its utility and determine if it is the optimal sequence for aiding in that specific clinical situation. It is thus important that clinical medical physicists be able to understand and explain the physics behind the imaging techniques used in all aspects of clinical radiation oncology practice. This session will provide the basic physics for a variety of imaging modalities for applications that are highly relevant to radiation oncology practice: computed tomography (CT) (including kV, MV, cone beam CT [CBCT], and 4DCT), positron emission tomography (PET)/CT, magnetic resonance imaging (MRI), and imaging specific to brachytherapy (including ultrasound and some brachytherapy specific topics in MR). For each unique modality, the image formation process will be reviewed, trade-offs between image quality and other factors (e.g. imaging time or radiation dose) will be clarified, and typically used cases for each modality will be introduced. The current and near-future uses of these modalities and techniques in radiation oncology clinical practice will also be discussed. Learning Objectives: To review the basic physical science principles of CT, PET, MR, and ultrasound imaging. To understand how the images are created, and present their specific role in patient management and treatment planning for therapeutic radiation (both external beam and brachytherapy). To discuss when and how each specific imaging modality is currently used in clinical practice, as well as how they may come to be used in the near future.

60 APPLIED LIFE SCIENCES↗
NASA NTRS1990

Shape optimization for maximum stability and dynamic stiffness

Any optimization of structures for maximum stability or for maximum dynamic stiffness deals with an eigenvalue problem. The goal of this optimization is to raise the lowest eigenvalue (or eigenvalues) of the problem to its highest (optimal) level at a constant volume of the structure. Likely the lowest eigenvalue may be either inherently multi-modal or it can become multi-modal as a result of the optimization process. The multimodeness introduces some ambiguity to the eigenvalue problem and make the optimization difficult to handle. Thus far, only the simplest cases of multi-modal structures have been effectively optimized using rather elaborate analytical methods. Numerous publications report design of a minimum volume structure with different eigenvalues constraints, in which, however, the modality of the problem is assumed a priori. The method presented here utilizes a multi-modal optimality criteria and allows for inclusion of an arbitrary number of buckling or vibrations modes which might influence the optimization process. The real multi-modality of the problem, that is the number of modes participating in the final optimal design is determined iteratively. Because of a natural use of the FEM technique the method is easy to program and might be helpful in design of large flexible space structures.

Szyszkowski, W.↗
NASA NTRS1996

Controlling Flexible Robot Arms Using High Speed Dynamics Process

A robot manipulator controller for a flexible manipulator arm having plural bodies connected at respective movable hinges and flexible in plural deformation modes corresponding to respective modal spatial influence vectors relating deformations of plural spaced nodes of respective bodies to the plural deformation modes, operates by computing articulated body quantities for each of the bodies from respective modal spatial influence vectors, obtaining specified body forces for each of the bodies, and computing modal deformation accelerations of the nodes and hinge accelerations of the hinges from the specified body forces, from the articulated body quantities and from the modal spatial influence vectors. In one embodiment of the invention, the controller further operates by comparing the accelerations thus computed to desired manipulator motion to determine a motion discrepancy, and correcting the specified body forces so as to reduce the motion discrepancy. The manipulator bodies and hinges are characterized by respective vectors of deformation and hinge configuration variables, and computing modal deformation accelerations and hinge accelerations is carried out for each one of the bodies beginning with the outermost body by computing a residual body force from a residual body force of a previous body and from the vector of deformation and hinge configuration variables, computing a resultant hinge acceleration from the body force, the residual body force and the articulated hinge inertia, and revising the residual body force modal body acceleration.

Jain, Abhinandan↗
NASA NTRS2020

TURBOMAT-FR: Turbomachinery Aeroelastic Forced Response Analysis Automation Using MATLAB® Part 2

The primary aim of this effort is to develop a software tool named “Turbomachinery Aeroelastic Analysis Tool for Forced Response (TURBOMAT-FR)” using MATLAB® (The MathWorks, Inc.) scripts. The tool will aid in performing routine forced response analysis of turbomachinery fan blades with the aid of the modal summation method (MSUM). The MSUM approach requires a modal solution consisting of modal displacements, frequencies, and stresses. The MATLAB® scripts facilitate easy extraction of the required quantities from the computational fluid dynamics (CFD) and MSC Nastran (Hexagon AB) solution files. These quantities are subsequently utilized by the MSUM approach to perform a complete forced response analysis using the MATLAB® scripts. The MATLAB® scripts in TURBOMAT-FR are utilized in postprocessing of the MSC Nastran finite element analysis outputs in three types of solutions or steps, namely (1) stresses and displacements from static or steady response solution, (2) unsteady stresses and displacements from direct forced response solution, and (3) modal solution containing modal displacements and modal stresses. In step (4), separate MATLAB® scripts are also developed to read the processed outputs in step (3) and perform forced response analysis using MSUM. It should be noted that the direct forced response solution from step (2) will provide for a comparison with those obtained from the MSUM approach in steps (3) and (4). The TURBOMAT-FR MATLAB® scripts mentioned previously are presented in two reports designated Parts 1 and 2. Part 1 presents the scripts needed to accomplish steps (1) and (2). The current report, Part 2, presents the scripts needed to accomplish steps (3) and (4), noted previously. The TURBOMAT-FR MATLAB® scripts provided here in Part 2 facilitate the calculation of unsteady stresses using MSUM and provide an automated procedure associated with aeroelastic forced response analysis with different pressure files. The unsteady stresses calculated using MSUM can be compared with those presented in Part 1. A cantilevered blade-alone model subjected to a realistic pressure loading to a boundary was used for static and unsteady direct forced response analysis to demonstrate the effectiveness of the TURBOMATFR MATLAB® scripts.

T S R Reddy↗
NASA NTRS2024

X-57 Cruise Motor GVT Using Fixed-Base Correction Technique

The National Aeronautics and Space Administration (NASA) Armstrong Flight Research Center (AFRC) completed a modal survey of the X-57 Maxwell aircraft cruise motor system to help inform cruise motor redesign efforts. X-57 Maxwell was an electric propulsion demonstrator aircraft developed by NASA to inform airworthiness standards for electrified-aircraft. The cruise motor system modal survey was completed in spring of 2023 utilizing the fixed-base correction (FBC) ground vibration test (GVT) technique developed by ATA Engineering, to decouple the motor modes from the aircraft modes. Previously during the full aircraft GVT, a detailed modal assessment of the cruise motors was not performed. Owing to the X-57 project’s phase in the aircraft development cycle when the motor redesign effort occurred, the cruise motor GVT could only be performed with the cruise motor system installed on the aircraft, with most of its installation hardware (wiring, baffling, sensors, etc.) attached. An impact hammer was used to provide excitation input at various locations within the tight confines of the cruise motor installation. To better support motor redesign efforts, the FBC methodology was utilized to fix, separate and de-couple the cruise motor modes from aircraft modal response. During the GVT, this required additional impact tap tests on candidate fixed-boundary points for each degree of freedom (DOF) to be fixed. Additional triaxial accelerometers installed at the candidate points were used to compute frequency response functions (FRFs) in X, Y, and Z directions to enable those DOFs to be numerically fixed. Test data was acquired using Hottinger Brüel & Kjær’s LAN-XI data acquisition hardware and BK Connect software. FBC post-test processing was performed using the Structural Modification Using Frequency Response Functions (SMURF) technique with ATA Engineering’s Interface between MATLAB, Analysis, Test (IMAT) software. Utilizing the FBC technique relieved test engineers from having to instrument the entire aircraft to identify and separate aircraft response from cruise motor modes of interest. The FBC technique also permitted structural analysis engineers to omit secondary components from their finite element model (FEM) of the cruise motor system. This FBC modal survey was successful, and the first time NASA AFRC utilized the FBC method on an aircraft rather than a test fixture, and also using an impact hammer rather than multiple shakers allowing significant project schedule and cost savings

Modal Survey↗
DOE OSTI2019

ACC/AATS/AHA/ASE/ASNC/HRS/SCAI/SCCT/SCMR/STS 2019 Appropriate Use Criteria for Multimodality Imaging in the Assessment of Cardiac Structure and Function in Nonvalvular Heart Disease

This document is the second of 2 companion appropriate use criteria (AUC) documents developed by the American College of Cardiology, American Association for Thoracic Surgery, American Heart Association, American Society of Echocardiography, American Society of Nuclear Cardiology, Heart Rhythm Society, Society for Cardiovascular Angiography and Interventions, Society of Cardiovascular Computed Tomography, Society for Cardiovascular Magnetic Resonance, and Society of Thoracic Surgeons. The first document (J Am Coll Cardiol 2017;70:1647-1672) addresses the evaluation and use of multimodality imaging in the diagnosis and management of valvular heart disease, whereas this document addresses this topic with regard to structural (nonvalvular) heart disease. While dealing with different subjects, the 2 documents do share a common structure and feature some clinical overlap. The goal of the companion AUC documents is to provide a comprehensive resource for multimodality imaging in the context of structural and valvular heart disease, encompassing multiple imaging modalities. Using standardized methodology, the clinical scenarios (indications) were developed by a diverse writing group to represent patient presentations encountered in everyday practice and included common applications and anticipated uses. Where appropriate, the scenarios were developed on the basis of the most current American College of Cardiology/American Heart Association Clinical Practice Guidelines. A separate, independent rating panel scored the 102 clinical scenarios in this document on a scale of 1 to 9. Scores of 7 to 9 indicate that a modality is considered appropriate for the clinical scenario presented. Midrange scores of 4 to 6 indicate that a modality may be appropriate for the clinical scenario, and scores of 1 to 3 indicate that a modality is considered rarely appropriate for the clinical scenario. The primary objective of the AUC is to provide a framework for the assessment of these scenarios by practices that will improve and standardize physician decision making. AUC publications reflect an ongoing effort by the American College of Cardiology to critically and systematically create, review, and categorize clinical situations in which diagnostic tests and procedures are utilized by physicians caring for patients with cardiovascular diseases. The process is based on the current understanding of the technical capabilities of the imaging modalities examined.

62 RADIOLOGY AND NUCLEAR MEDICINE↗
DOE OSTI2012

Approach for Selection of Rayleigh Damping Parameters Used for Time History Analysis

Nonlinearities, whether geometric or material, need to be addressed in seismic analysis. One good analysis method that can address these nonlinearities is direct time integration with Rayleigh damping. Modal damping is the damping typically specified in seismic analysis Codes and Standards. Modal damping is constant for all frequencies where Rayleigh damping varies with frequency. An approach is proposed here for selection of Rayleigh damping coefficients to be used in seismic analyses that is consistent with given Modal damping. The approach uses the difference between the modal damping response and the Rayleigh damping response along with effective mass properties of the model being evaluated to match overall system response levels. This paper provides a simple example problem to demonstrate the approach. It also provides results for a finite element model representing an existing piping system. Displacement, acceleration, and stress results are compared from model runs using modal damping and model runs using Rayleigh damping with coefficients selected using the proposed method.

42 ENGINEERING↗
DOE OSTI2019

Multi-degree of Freedom Energy Analysis for Identification of Failure Risk in Structural Components Subjected to Random Vibration and Shock Loading

When designing or analyzing a mechanical system, energy quantities provide insight into the severity of shock and vibration environments; however, the energy methods in the literature do not address localized behavior because energy quantities are usually computed for an entire structure. The main objective of this paper is to show how to compute the energy in the components of a mechanical system. The motivation for this work is that most systems fail functionally due to component failure, not because the primary structure was overloaded, and the ability to easily compute the spatial distribution of energy helps identify failure sensitive components. The quantity of interest is input energy. That input energy can be decoupled modally is well known. What is less appreciated is that input energy can be computed at the component level exactly, using the component effective modal mass. We show the steady state input energy can be decomposed both spatially and modally and computed using input power spectra. A numerical example illustrates the spatial and modal decomposition of input energy and its utility in identifying components at risk of damage in random vibration and shock environments. Our work shows that the modal properties of the structure and the spectral content of the input must be considered together to assess damage risk. Because input energy includes absorbed energy as well as relative kinetic energy and dissipated energy, it is the recommended energy quantity for assessing the severity for both random vibration and shock environments on a structure.

42 ENGINEERING↗
DOE OSTI2015

SU-E-J-218: Novel Validation Paradigm of MRI to CT Deformation of Prostate

Purpose: Deformable registration algorithms are inherently difficult to characterize in the multi-modality setting due to a significant differences in the characteristics of the different modalities (CT and MRI) as well as tissue deformations. We present a unique paradigm where this is overcome by utilizing a planning-MRI acquired within an hour of the planning-CT serving as a surrogate for quantifying MRI to CT deformation by eliminating the issues of multi-modality comparisons. Methods: For nine subjects, T2 fast-spin-echo images were acquired at two different time points, the first several weeks prior to planning (diagnostic-MRI) and the second on the same day as the planning-CT (planning-MRI). Significant effort in patient positioning and bowel/bladder preparation was undertaken to minimize distortion of the prostate in all datasets. The diagnostic-MRI was rigidly and deformably aligned to the planning-CT utilizing a commercially available deformable registration algorithm synthesized from local registrations. Additionally, the quality of rigid alignment was ranked by an imaging physicist. The distances between corresponding anatomical landmarks on rigid and deformed registrations (diagnostic-MR to planning-CT) were evaluated. Results: It was discovered that in cases where the rigid registration was of acceptable quality the deformable registration didn’t improve the alignment, this was true of all metrics employed. If the analysis is separated into cases where the rigid alignment was ranked as unacceptable the deformable registration significantly improved the alignment, 4.62mm residual error in landmarks as compared to 5.72mm residual error in rigid alignments with a p-value of 0.0008. Conclusion: This paradigm provides an ideal testing ground for MR to CT deformable registration algorithms by allowing for inter-modality comparisons of multi-modality registrations. Consistent positioning, bowel and bladder preparation may Result in higher quality rigid registrations than typically achieved which limits the impact of deformable registrations. In this study cases where significant differences exist, deformable registrations provide significant value.

60 APPLIED LIFE SCIENCES↗
DOE OSTI2015

SU-E-T-308: Dosimetric Comparison of SBRT VMAT Treatment Plans Generated for 6 MV, 6 MV FFF, and 10 MV FFF Photon Beams

Purpose: To assess differences in treatment plan quality between VMAT stereotactic body plans generated using the 6 MV, 6 MV FFF, and 10 MV FFF modalities available in our clinic. Plans for lung, spine, and other sites were compared to see if there is any advantage of one modality over the other. Methods: Treatment plans done for actual SBRT patients were selected. Groups of ten lung plans, five spine plans, and five plans from other sites were selected. New treatment plans were generated for each plan using the Varian Eclipse AAA algorithm. The constraints were kept the same as used in the actual plans, but the same version of software was used to generate plans for the three modalities. In addition, because there are natural variations in plans re-done with the same dose constraints, one of the lung plans was repeated ten times to assess those differences. Volumes of the 100%, 90%, 50%, 20% and 10% isodose surfaces were compared. Maximum dose two centimeters from the PTV were compared, as well as the volume of the 105% isodose surface outside of the PTV. In addition, the 20 Gray lung volume was compared for the lung plans. The values of these parameters were divided by the values for the 6 MV plans for comparison. Average and standard deviations were obtained for quantities in each group. The Student t test was done to determine if differences were seen at the 95% confidence level. Results: Comparison of the treatment plans showed no significant differences when assessing these volumes and doses. There were not any trends seen when comparing modalities as a function of PTV volume either. Conclusion: There is no obvious dosimetric advantage in selection of one modality over another for these types of SBRT plans.

60 APPLIED LIFE SCIENCES↗