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At least 1,387 records · Page 77

Investigating Neuro-Consequences of Spaceflight Using Drosophila Melanogaster

Research on human acclimation to spaceflight, including the recent NASA's Twin Study, reports complex effects of the spaceflight environment on health, with both acute and prolonged changes in multiple tissues. Spaceflight includes multiple factors such as microgravity, ionizing radiation, physiological stress, and disrupted circadian rhythms, that have been shown to contribute to pathophysiological responses that target immunity, bone and muscle integrity, cardiovascular and nervous systems. In this study, we used a well-established spaceflight model organism, Drosophila melanogaster, to assess spaceflight-associated changes on the nervous system. With 75% disease gene orthology to humans, short generation time, large sample size and ease of genetic, neuronal and behavioral studies, Drosophila is an excellent model to study nervous system dysfunction. Here, we present results from MVP-Fly-01 spaceflight mission that was launched on SpaceX CRS-14. The MVP hardware (developed by Techshot) used in this mission enabled us to have an in-flight 1g centrifuge, to distinguish the changes resulting from gravity versus those induced by other environmental factors associated with spaceflight. We observe behavioral impairments (p<0.001) and synaptic deficits, including decreased synaptic connections (p<0.05), in 3rd instar larvae which were developed in space. Furthermore, space-grown microgravity adults show a decrease in neuronal (p<0.05) and dendritic field (p<0.01) in adult brains coupled with an increased number of apoptotic cells (p<0.001) compared to in-flight 1g controls, suggesting increased neuronal loss under spaceflight conditions. In summary, we observe that altered gravity leads to gross neurological deficits. To better understand the long-term effects of spaceflight on the nervous system, longitudinal and multigenerational changes were also identified. This study will help elucidate the different approaches to prevent nervous system dysfunction in astronauts during spaceflight, while also contributing to a better understanding of the pathways that are related to some CNS disorders on Earth.

Iyer, Janani↗

Concept Assessment of a Fission Fragment Rocket Engine (FFRE) Propelled Spacecraft

The March, 2012 issue of Aerospace America stated that ―the near-to-medium prospects for applying advanced propulsion to create a new era of space exploration are not very good. In the current world, we operate to the Moon by climbing aboard a Carnival Cruise Lines vessel (Saturn 5), sail from the harbor (liftoff) shedding whole decks of the ship (staging) along the way and, having reached the return leg of the journey, sink the ship (burnout) and return home in a lifeboat (Apollo capsule). Clearly this is an illogical way to travel, but forced on Explorers by today's propulsion technology. However, the article neglected to consider the one propulsion technology, using today's physical principles that offer continuous, substantial thrust at a theoretical specific impulse of 1,000,000 sec. This engine unequivocally can create a new era of space exploration that changes the way spacecraft operate. Today's space Explorers could travel in Cruise Liner fashion using the technology not considered by Aerospace America, the novel Dusty Plasma Fission Fragment Rocket Engine (FFRE). This NIAC study addresses the FFRE as well as its impact on Exploration Spacecraft design and operation. It uses common physics of the relativistic speed of fission fragments to produce thrust. It radiatively cools the fissioning dusty core and magnetically controls the fragments direction to practically implement previously patented, but unworkable designs. The spacecraft hosting this engine is no more complex nor more massive than the International Space Station (ISS) and would employ the successful ISS technology for assembly and check-out. The elements can be lifted in "chunks" by a Heavy Lift Launcher. This Exploration Spacecraft would require the resupply of small amounts of nuclear fuel for each journey and would be an in-space asset for decades just as any Cruise Liner on Earth. This study has synthesized versions of the FFRE, integrated one concept onto a host spacecraft designed for manned travel to Jupiter's moon, Callisto, and assessed that round trip journey. This engine, although unoptimized, produced 10 pounds force of thrust at a delivered specific impulse of 527,000 seconds for the entire 15-year mission while providing enormous amounts of electrical power to the spacecraft. A payload of 60 metric tons, included in the 300 metric ton vehicle, was carried to Callisto and back; the propellant tanks holding the 4 metric tons of fuel were not jettisoned in the process. The study concluded that the engine and spacecraft are within today's technology, could be built, tested, launched on several SLS (Space Launch System) (or similar) launchers, integrated, checked out, moved to an in-space base such as at a Lagrange point and operated for decades.

Engine↗

A preliminary investigation of the potential applicability of the IPAD system to non-aerospace industry

A study of the applicability of the planned Integrated Programs for Aerospace-Vehicle Design (IPAD) system to the design activities of non-aerospace industries was carried out. It was determined that IPAD could be of significant benefit to a number of industries, with the most likely users being the heavy construction and automotive industries. Two additional short studies were initiated to investigate the possible impact of IPAD on a national energy program and on urban and regional planning activities of local and state governments. These initial studies indicated the possibility of significant payoff in these areas and the need for further investigations. It was also determined that utilization of IPAD by non-aerospace industries will probably involve a long stepwise process, since these industries maintain a policy of gradual introduction of new technology.

Hulbert, L. E.↗

Scramjet nozzle design and analysis as applied to a highly integrated hypersonic research airplane

The configuration and performance of the propulsion system for the hypersonic research vehicle are discussed. A study of the interactions between propulsion and aerodynamics of the highly integrated vehicle was conducted. The hypersonic research vehicle is configured to test the technology of structural and thermal protection systems concepts and the operation of the propulsion system under true flight conditions for most of the hypersonic flight regime. The subjects considered are: (1) research vehicle and scramjet engine configurations to determine fundamental engine sizing constraints, (2) analytical methods for computing airframe and propulsion system components, and (3) characteristics of a candidate nozzle to investigate vehicle stability and acceleration performance.

Small, W. J.↗

Technology Developed In Two Space Projects

Two projects examined for their influences on commercial products and future space missions. Three-volume report presents study of technological benefits of two spaceflight projects, Galileo, and Hubble space telescope. Study focused on equipment and computer programs developed between initial approval of projects and integration and testing of the systems. Volume 1 presents overview of study, discusses methods of collection and evaluation of data, and offers conclusion and recommendations. Volume 2 describes interview process and summarizes raw data. Volume 3 contains technology-assessment sheets for developments.

Joseph, Carlton H.↗

A study of the adequacy of quasi-geostrophic dynamics for modeling the effect of frontal cyclones on the larger scale flow

The evolution of individual cyclone waves is studied in order to see how well quasi-geostrophic (QG) dynamics can simulate the behavior of primitive equations (PE) dynamics. This work is an extension of a similar study (Mudrick, 1982); emphasis is placed here on adding a frontal zone and other more diverse features to the basic states used. In addition, sets of PE integrations, with and without friction, are used to study the formation of surface occluded fronts within the evolving cyclones. Results of the study are summarized at the beginning of the report.

Mudrick, Stephen↗

The Integrated Airframe/Propulsion Control System Architecture program (IAPSA)

The Integrated Airframe/Propulsion Control System Architecture program (IAPSA) is a two-phase program which was initiated by NASA in the early 80s. The first phase, IAPSA 1, studied different architectural approaches to the problem of integrating engine control systems with airframe control systems in an advanced tactical fighter. One of the conclusions of IAPSA 1 was that the technology to construct a suitable system was available, yet the ability to create these complex computer architectures has outpaced the ability to analyze the resulting system's performance. With this in mind, the second phase of IAPSA approached the same problem with the added constraint that the system be designed for validation. The intent of the design for validation requirement is that validation requirements should be shown to be achievable early in the design process. IAPSA 2 has demonstrated that despite diligent efforts, integrated systems can retain characteristics which are difficult to model and, therefore, difficult to validate.

Daniel L Palumbo↗

Performance Analysis of a NASA Integrated Network Array

The Space Communications and Navigation (SCaN) Program is planning to integrate its individual networks into a unified network which will function as a single entity to provide services to user missions. This integrated network architecture is expected to provide SCaN customers with the capabilities to seamlessly use any of the available SCaN assets to support their missions to efficiently meet the collective needs of Agency missions. One potential optimal application of these assets, based on this envisioned architecture, is that of arraying across existing networks to significantly enhance data rates and/or link availabilities. As such, this document provides an analysis of the transmit and receive performance of a proposed SCaN inter-network antenna array. From the study, it is determined that a fully integrated internetwork array does not provide any significant advantage over an intra-network array, one in which the assets of an individual network are arrayed for enhanced performance. Therefore, it is the recommendation of this study that NASA proceed with an arraying concept, with a fundamental focus on a network-centric arraying.

Nessel, James A.↗

Flight deck benefits of integrated data link communication

A fixed-base, piloted simulation study was conducted to determine the operational benefits that result when air traffic control (ATC) instructions are transmitted to the deck of a transport aircraft over a digital data link. The ATC instructions include altitude, airspeed, heading, radio frequency, and route assignment data. The interface between the flight deck and the data link was integrated with other subsystems of the airplane to facilitate data management. Data from the ATC instructions were distributed to the flight guidance and control system, the navigation system, and an automatically tuned communication radio. The co-pilot initiated the automation-assisted data distribution process. Digital communications and automated data distribution were compared with conventional voice radio communication and manual input of data into other subsystems of the simulated aircraft. Less time was required in the combined communication and data management process when data link ATC communication was integrated with the other subsystems. The test subjects, commercial airline pilots, provided favorable evaluations of both the digital communication and data management processes.

Waller, Marvin C.↗

Study and prototype of data system interactions for the Earth Observing System Data and Information System

A crucial part of the Earth Observing System (EOS) is its Data and Information System (EOSDIS). The success of EOS depends not only on its instruments and science studies, but also on its ability to help scientists integrate data sets of geophysical and biological measurements taken by various instruments and investigators. NASA contractors have completed Phase B studies of EOSDIS, in particular its architecture, functionality, and user interfacing. At this point in time, it may seem impossible to exercise the EOSDIS or any of its components since they do not exist; i.e., if the EOSDIS is accepted as a totally new system, distinct from any existing DIS. However, if EOSDIS is seen as evolving from existing data systems, then some limited prototyping studies can be conducted by using currently functioning systems. In support of both the EOSDIS Science Advisory Panel and the EOSDIS Project, a prototyping activity was carried out by a cross section of interdisciplinary scientists. That prototyping activity is summarized and some conclusions are drawn that can be used by NASA-Goddard to evaluate and modify the specifications soon to be released in an RFP to build EOSDIS.

Emmitt, G. D.↗

Advanced EVA Capabilities: A Study for NASA's Revolutionary Aerospace Systems Concept Program

This report documents the results of a study carried out as part of NASA s Revolutionary Aerospace Systems Concepts Program examining the future technology needs of extravehicular activities (EVAs). The intent of this study is to produce a comprehensive report that identifies various design concepts for human-related advanced EVA systems necessary to achieve the goals of supporting future space exploration and development customers in free space and on planetary surfaces for space missions in the post-2020 timeframe. The design concepts studied and evaluated are not limited to anthropomorphic space suits, but include a wide range of human-enhancing EVA technologies as well as consideration of coordination and integration with advanced robotics. The goal of the study effort is to establish a baseline technology "road map" that identifies and describes an investment and technical development strategy, including recommendations that will lead to future enhanced synergistic human/robot EVA operations. The eventual use of this study effort is to focus evolving performance capabilities of various EVA system elements toward the goal of providing high performance human operational capabilities for a multitude of future space applications and destinations. The data collected for this study indicate a rich and diverse history of systems that have been developed to perform a variety of EVA tasks, indicating what is possible. However, the data gathered for this study also indicate a paucity of new concepts and technologies for advanced EVA missions - at least any that researchers are willing to discuss in this type of forum.

Hoffman, Stephen J.↗

TPSAS-NF1676L-12284-DND

A much desired capability for conceptual design of aircraft is the ability to rapidly and accurately evaluate new concepts to avoid adverse trade decisions that can hinder the development in the later stages of design. For the conceptual design of supersonic aircraft, it is important to evaluate the robustness of a new low-boom concept. Here, robustness means that the aircraft configuration has low-boom ground signatures at both under-track and off-track locations. An integration process for off-track boom analysis is developed to facilitate robust design of low-boom supersonic aircraft. The integrated off-track analysis can also be used to study sonic boom impact on flight corridors where flight conditions and ground elevation might have a significant effect on ground signatures. The key for off-track sonic boom analysis is accurate solutions for off-body pressure distribution along the lower region of a cylinder cut around the aircraft. To ensure the numerical accuracy of the off-body pressure distribution, a mesh study is performed to determine the mesh requirements for off-track analysis as well as comparisons between Cart3D and USM3D off-track sonic boom results for various low-boom concepts. The integrated and automated process makes it possible to study the environmental impact of future supersonic concepts in the early design phases and support the planning of future flight corridors to mitigate sonic boom effects.

Irian Ordaz↗

NASA-UVA Light Aerospace Alloy and Structure Technology Program Supplement: Aluminum-Based Materials for High Speed Aircraft

This is the final report of the study "Aluminum-Based Materials for High Speed Aircraft" which had the objectives (1) to identify the most promising aluminum-based materials with respect to major structural use on the HSCT and to further develop those materials and (2) to assess the materials through detailed trade and evaluation studies with respect to their structural efficiency on the HSCT. The research team consisted of ALCOA, Allied-Signal, Boeing, McDonnell Douglas, Reynolds Metals and the University of Virginia. Four classes of aluminum alloys were investigated: (1) I/M 2XXX containing Li and I/M 2XXX without Li, (2) I/M 6XXX, (3) two P/M 2XXX alloys, and (4) two different aluminum-based metal matrix composites (MMC). The I/M alloys were targeted for a Mach 2.0 aircraft and the P/M and MMC alloys were targeted for a Mach 2.4 aircraft. Design studies were conducted using several different concepts including skin/stiffener (baseline), honeycomb sandwich, integrally stiffened and hybrid adaptations (conventionally stiffened thin-sandwich skins). Alloy development included fundamental studies of coarsening behavior, the effect of stress on nucleation and growth of precipitates, and fracture toughness as a function of temperature were an integral part of this program. The details of all phases of the research are described in this final report.

Starke, E. A., Jr.↗

Derivatives Across Adaptive-Step Integration Accurately and Efficiently

The numerical integration of ordinary differential equations (ODEs) is common in trajectory optimization. Previous studies have shown that the use of adaptive-step Runge-Kutta integration schemes can introduce errors in the derivatives due to non-differentiable behavior within the integration scheme itself. The authors previously demonstrated the use of an implicit adaptation to the Runge-Kutta methods to mitigate this issue, but at a significant computational cost. In this work, the authors demonstrate an explicit adaptation to the Runge-Kutta methods to address the issue that does not incur a significant computational cost.

Kaushik Ponnapalli↗

Integrating Chlorophyll fapar and Nadir Photochemical Reflectance Index from EO-1/Hyperion to Predict Cornfield Daily Gross Primary Production

The concept of light use efficiency (Epsilon) and the concept of fraction of photosynthetically active ration (PAR) absorbed for vegetation photosynthesis (PSN), i.e., fAPAR (sub PSN), have been widely utilized to estimate vegetation gross primary productivity (GPP). It has been demonstrated that the photochemical reflectance index (PRI) is empirically related to ε. An experimental US Department of Agriculture (USDA) cornfield in Maryland was selected as our study field. We explored the potential of integrating fAPAR(sub chl) (defined as the fraction of PAR absorbed by chlorophyll) and nadir PRI (PRI(sub nadir)) to predict cornfield daily GPP. We acquired nadir or near-nadir EO-1/Hyperion satellite images that covered the cornfield and took nadir in-situ field spectral measurements. Those data were used to derive the PRI(sub nadir) and fAPAR (sub chl). The fAPAR (sub chl) is retrieved with the advanced radiative transfer model PROSAIL2 and the Metropolis approach, a type of Markov Chain Monte Carlo (MCMC) estimation procedure. We define chlorophyll light use efficiency Epsilon (sub chl) as the ratio of vegetation GPP as measured by eddy covariance techniques to PAR absorbed by chlorophyll (Epsilon(sub chl) = GPP/APAR (sub chl). Daily Epsilon (sub chl) retrieved with the EO-1 Hyperion images was regressed with a linear equation of PRI (sub nadir) Epsilon (sub chl) = Alpha × PRI (sub nadir) + Beta). The satellite Epsilon(sub chl- PRI (sub nadir) linear relationship for the cornfield was implemented to develop an integrated daily GPP model [GPP = (Alpha × PRI(sub nadir) + Beta) × fAPAR (sub chl) × PAR], which was evaluated with fAPAR (sub chl) and PRI (sub nadir) retrieved from field measurements. Daily GPP estimated with this fAPAR (sub chl-) PRI (nadir) integration model was strongly correlated with the observed tower in-situ daily GPP (R(sup 2) = 0.93); with a root mean square error (RMSE) of 1.71 g C mol−(sup -1) PPFD and coefficient of variation (CV) of 16.57%. Both seasonal Epsilon (sub chl) and PRI (sub nadir) were strongly correlated with fAPAR (sub chl ) retrieved from field measurements, which indicates that chlorophyll content strongly affects seasonal epsilon (sub chl) and PRI (sub nadir). We demonstrate the potential capacity to monitor GPP with space-based visible through shortwave infrared (VSWIR) imaging spectrometers such as NASA's soon to be decommissioned EO- 1/Hyperion and the future Hyperspectral Infrared Imager (HyspIRI).

HyspIRI↗

Development of a software interface for optical disk archival storage for a new life sciences flight experiments computer

The current Life Sciences Laboratory Equipment (LSLE) microcomputer for life sciences experiment data acquisition is now obsolete. Among the weaknesses of the current microcomputer are small memory size, relatively slow analog data sampling rates, and the lack of a bulk data storage device. While life science investigators normally prefer data to be transmitted to Earth as it is taken, this is not always possible. No down-link exists for experiments performed in the Shuttle middeck region. One important aspect of a replacement microcomputer is provision for in-flight storage of experimental data. The Write Once, Read Many (WORM) optical disk was studied because of its high storage density, data integrity, and the availability of a space-qualified unit. In keeping with the goals for a replacement microcomputer based upon commercially available components and standard interfaces, the system studied includes a Small Computer System Interface (SCSI) for interfacing the WORM drive. The system itself is designed around the STD bus, using readily available boards. Configurations examined were: (1) master processor board and slave processor board with the SCSI interface; (2) master processor with SCSI interface; (3) master processor with SCSI and Direct Memory Access (DMA); (4) master processor controlling a separate STD bus SCSI board; and (5) master processor controlling a separate STD bus SCSI board with DMA.

Bartram, Peter N.↗