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At least 1,387 records · Page 77

Incidence and predictors of loss to follow-up among adult patients receiving antiretroviral therapy in Central Ethiopia: a multi-center retrospective cohort study

Background: Globally, loss to follow-up (LTFU) remains a significant public health concern despite the rapid expansion of antiretroviral medication programs. It is a significant cause of treatment failure and threatens the enhancement of HIV treatment outcomes among patients on antiretroviral therapy (ART). However, there is a paucity of evidence on its incidence and predictors in Ethiopia. Thus, this study aimed to examine the incidence and predictors of LTFU among adult HIV patients receiving ART at hospitals in Central Ethiopia. Methods: A multi-centered facility-based retrospective cohort study was conducted among 432 randomly selected adult patients who received antiretroviral therapy. Data were entered into EpiData version 3.1 and exported to Stata version 14 for analysis. The Kaplan–Meier failure function was employed to determine the overall failure estimates, and the log-rank test was used to compare the probability of failure among the different categories of variables. The Cox proportional hazard model was used to identify independent predictors of LTFU. Results: Overall, 172 (39.8%) study participants were lost to follow-up over the 10-year follow-up period with an incidence rate of 8.12 (95% CI: 7.11, 9.09) per 1,000 person-months. Undisclosed HIV status (AHR: 1.96, 95% CI: 1.14, 3.36), not able to work (AHR: 1.84, 95% CI: 1.13, 2.22), opportunistic infections (AHR: 3.13, 95% CI: 2.17, 4.52), CD4 < 200 cell/mL (AHR: 1.95, 95% CI: 1.18, 3.21), not receiving isoniazid preventive therapy (IPT) (AHR: 2.57, 95% CI: 1.62, 4.06), not participating in clubs (AHR: 1.68, 95% CI: 1.10, 2.22), side effects of drugs (AHR: 1.44, 95% CI: 1.02, 2.04), and high viral load (AHR: 3.15, 95% CI: 1.81, 5.47) were identified as significant predictors of loss to follow-up. Conclusion: In this study, the incidence of LTFU was high. The focus should be on creating awareness and prevention programs that aim to reduce loss to follow-up by continuing counseling, especially on the negative effects of loss to follow-up and the benefits of ART care.

60 APPLIED LIFE SCIENCES↗

The Anthropology of Aquaculture

Aquaculture is nothing new. It has a long, fascinating history that stretches from antiquity at least 8,000 years ago. What is new is the evolution of aquaculture in modern times into highly intensive monocultures which arose in the 1970–1980's. Modern aquaculture production has grown worldwide but remains concentrated in Asia due to the: (1) increased demands for aquatic foods as explosive population growth occurred in coastal cities with increasing affluence, (2) expansion of scientific and engineering breakthroughs, (3) high export values of aquatic foods, and (4) sharp decline of costs of global to local transport/shipping. The pioneering anthropologist Claude Levi-Strauss brought the idea of “structuralism” to anthropology: the concept that societies throughout history followed universal patterns of behavior. A qualitative document analysis of the key anthropological literature to assess aquaculture developments from antiquity to the beginning of the modern era was conducted to evaluate if there was adequate evidence to support a theory of anthropological “structuralism” for aquaculture in human history. Seven case studies of the cultural/environmental history of aquaculture were reviewed in diverse parts of the world (China, Australia, Egypt, Europe, South America, Canada/USA, Hawai'i). Analysis supports the structural theory that whenever the demands of aquatic/seafood-eating peoples exceeded the abilities of their indigenous fishery ecosystems to provide for them, they developed aquaculture. Modern aquaculture concepts and new communities of practice in “restoration aquaculture” have beginnings in Indigenous anthropology and archeology in aquaculture and point the way for Indigenous nations to engage as leaders of the United Nations Food and Agriculture Organization (FAO) ecosystem approach to aquaculture worldwide. Bringing ancient knowledge of Indigenous aquaculture into the modern context is an essential part of an alternative, “radical transformation” of modern aquaculture. There is an urgent need to develop and promote locally designed and culturally appropriate aquaculture systems that fit into the livelihoods of communities as part of a larger, diverse portfolio of food security.

54 ENVIRONMENTAL SCIENCES↗

The Missing Pieces: The Role of Secretion Systems in Campylobacter jejuni Virulence

Campylobacter jejuni is likely the most common bacterial cause of gastroenteritis worldwide, responsible for millions of cases of inflammatory diarrhea characterized by severe abdominal cramps and blood in the stool. Further, C. jejuni infections are associated with post-infection sequelae in developed countries and malnutrition and growth-stunting in low- and middle-income countries. Despite the increasing prevalence of the disease, campylobacteriosis, and the recognition that this pathogen is a serious health threat, our understanding of C. jejuni pathogenesis remains incomplete. In this review, we focus on the Campylobacter secretion systems proposed to contribute to host-cell interactions and survival in the host. Moreover, we have applied a genomics approach to defining the structural and mechanistic features of C. jejuni type III, IV, and VI secretion systems. Special attention is focused on the flagellar type III secretion system and the prediction of putative effectors, given that the proteins exported via this system are essential for host cell invasion and the inflammatory response. We conclude that C. jejuni does not possess a type IV secretion system and relies on the type III and type VI secretion systems to establish a niche and potentiate disease.

59 BASIC BIOLOGICAL SCIENCES↗

Exploring the Grid Value of Offshore Wind Energy in Oregon

The significant offshore wind energy potential of Oregon faces several challenges, including a power grid which was not developed for the purpose of transmitting energy from the ocean. The grid impacts of the energy resource are considered through the lenses of (i) resource complementarity with Variable Renewable Energy resources; (ii) correlations with load profiles from the four balancing authorities with territory in Oregon; and (iii) spatial value to regional and coastal grids as represented through a production cost model of the Western Interconnection. The capacity implications of the interactions between offshore wind and the historical east-to-west power flows of the region are discussed. The existing system is shown to accommodate more than two gigawatts of offshore wind interconnections with minimal curtailment. Through three gigawatts of interconnection, transmission flows indicate a reduction of coastal and statewide energy imports as well as minimal statewide energy exports.

17 WIND ENERGY↗

Characterization of Local and Systemic Impact of Whitefly (Bemisia tabaci) Feeding and Whitefly-Transmitted Tomato Mottle Virus Infection on Tomato Leaves by Comprehensive Proteomics

Tomato mottle virus (ToMoV) is a ssDNA plant begomovirus transmitted to solanaceous crops by the whitefly species complex (Bemisia tabaci), causing stunted growth, leaf mottling, and reduced fruit yield. Using a genetic repertoire of 7 genes, ToMoV pathogenesis includes manipulation of multiple plant biological processes to circumvent antiviral defenses. To further understand the effects of whitefly feeding and whitefly-transmitted ToMoV infection on tomato plants (Solanum lycopersicum ‘Florida Lanai’), we generated comprehensive protein profiles of leaves subjected to feeding by either (1) viruliferous whiteflies harboring ToMoV, or (2) non-viruliferous whiteflies, or (3) a no-feeding control. In each condition (1-3), whiteflies were confined to clip cages on a mature leaf for 3 days. The effects of whitefly feeding and ToMoV infection were measured both locally and systemically by sampling either a mature leaf directly from the site of whitefly feeding, or from a newly formed leaf 10 days post feeding (dpf). At 3 dpf, relatively few biological processes were affected specifically by ToMoV at the site of feeding, and include proteins associated with translation initiation and elongation, and plasmodesmata dynamics. In contrast, the systemic impacts of ToMoV on younger leaves at 10 dpf were more pronounced and included a virus-specific change in plant proteins associated with mRNA maturation and export, RNA-dependent DNA methylation, and other plant anti-viral transcriptional gene silencing systems. Our analysis supports previous findings and provides novel insight into biological processes in tomato altered locally and systemically by whitefly feeding and ToMoV infection.

59 BASIC BIOLOGICAL SCIENCES↗

Metalloproteomics Reveals Multi-Level Stress Response in Escherichia coli When Exposed to Arsenite

The arsRBC operon encodes a three-protein arsenic resistance system. ArsR regulates the transcription of the operon, while ArsB and ArsC are involved in exporting trivalent arsenic and reducing pentavalent arsenic, respectively. Previous research into Agrobacterium tumefaciens 5A has demonstrated that ArsR has regulatory control over a wide range of metal-related proteins and metabolic pathways. We hypothesized that ArsR has broad regulatory control in other Gram-negative bacteria and set out to test this. Here, we use differential proteomics to investigate changes caused by the presence of the arsR gene in human microbiome-relevant Escherichia coli during arsenite (AsIII) exposure. We show that ArsR has broad-ranging impacts such as the expression of TCA cycle enzymes during AsIII stress. Additionally, we found that the Isc [Fe-S] cluster and molybdenum cofactor assembly proteins are upregulated regardless of the presence of ArsR under these same conditions. An important finding from this differential proteomics analysis was the identification of response mechanisms that were strain-, ArsR-, and arsenic-specific, providing new clarity to this complex regulon. Given the widespread occurrence of the arsRBC operon, these findings should have broad applicability across microbial genera, including sensitive environments such as the human gastrointestinal tract.

Biochemistry & Molecular Biology↗

Use of a 360-Degree Underwater Camera to Characterize Artificial Reef and Fish Aggregating Effects around Marine Energy Devices

Marine energy devices must be attached to the seafloor by their foundations, pilings, or anchors, and will have other parts in the water column like the devices themselves, mooring lines, and power export cables running along the seafloor. The installation and presence of these artificial structures will create physical changes that can disrupt or create new habitats, and potentially alter the behavior of mobile organisms such as fish around a device by attracting them to these new artificial reefs and fish aggregating devices. In this study, we tested a new approach for monitoring fish activity around a marine energy device anchor: a 360-degree underwater camera to keep the target (a wave energy converter’s anchor) in the field of view of the camera. The camera was deployed in three configurations (hand-held, tripod, video lander) at sites with different hydrodynamics and underwater visibilities. The video lander was the best configuration: very stable, versatile, and easy to handle. The 360-degree field of view enabled observing and counting fishes, which were more abundant at dusk than dawn or noon, around the anchor. Despite remaining challenges, 360-degree cameras are useful tools for monitoring animal interactions with marine energy devices.

360-degree camera↗

Risk Retirement—Decreasing Uncertainty and Informing Consenting Processes for Marine Renewable Energy Development

Marine renewable energy (MRE) is under development in many coastal nations, adding to the portfolio of low carbon energy sources that power national electricity grids as well as off-grid uses in isolated areas and at sea. Progress in establishing the MRE industry, largely wave and tidal energy, has been slowed in part due to uncertainty about environmental risks of these devices, including harm to marine animals and habitats, and the associated concerns of regulators and stakeholders. A process for risk retirement was developed to organize and apply knowledge in a strategic manner that considered whether specific environmental effects are likely to cause harm. The risk retirement process was tested against two key MRE stressors: effects of underwater noise from operational MRE devices on marine animals, and effects of electromagnetic fields from MRE electrical export cables on marine animals. The effects of installation of MRE devices were not accounted for in this analysis. Applying the risk retirement process could decrease the need for costly investigations of each potential effect at every new MRE project site and help move the industry beyond current barriers.

16 TIDAL AND WAVE POWER↗

Cu Homeostasis in Bacteria: The Ins and Outs

Copper (Cu) is an essential trace element for all living organisms and used as cofactor in key enzymes of important biological processes, such as aerobic respiration or superoxide dismutation. However, due to its toxicity, cells have developed elaborate mechanisms for Cu homeostasis, which balance Cu supply for cuproprotein biogenesis with the need to remove excess Cu. This review summarizes our current knowledge on bacterial Cu homeostasis with a focus on Gram-negative bacteria and describes the multiple strategies that bacteria use for uptake, storage and export of Cu. We furthermore describe general mechanistic principles that aid the bacterial response to toxic Cu concentrations and illustrate dedicated Cu relay systems that facilitate Cu delivery for cuproenzyme biogenesis. Progress in understanding how bacteria avoid Cu poisoning while maintaining a certain Cu quota for cell proliferation is of particular importance for microbial pathogens because Cu is utilized by the host immune system for attenuating pathogen survival in host cells.

36 MATERIALS SCIENCE↗

Portuguese Wood Pellets Market: Organization, Production and Consumption Analysis

Wood pellets are a form of energy that can be seen as an alternative to fossil fuels, thus contributing to the reduction of greenhouse gas emissions. In other words, wood pellets can be considered a solution contributing to the mitigation of climate change. The use of wood pellets has grown significantly in recent years, with different markets emerging, such as Portugal, both from production and consumption perspectives. The wood pellet industry in Portugal began its development about 15 years ago, with the companies installed in the country initially almost exclusively dedicated to the production of wood pellets for export to central and northern European markets. However, over the years, the domestic market, initially considered insignificant, began to develop; it recently reached a considerable consuming share of the national production. This study presents an analysis of the Portuguese wood pellet market using data collected on the sector, and specifically on producers and consumers. The information was gathered using surveys presented directly to consumers and producers and through interviews with other stakeholders in the sector. From the analysis of the information, it was possible to understand the market’s dynamics, its current evolution and its prospects for the upcoming years, since it can already be considered mature and consolidated.

Nunes, Leonel J. R. (ORCID:0000000154048163)↗

Mapping intra-field yield variation using high resolution satellite imagery to integrate bioenergy and environmental stewardship in an agricultural watershed

Biofuels are important alternatives for meeting our future energy needs. Successful bioenergy crop production requires maintaining environmental sustainability and minimum impacts on current net annual food, feed, and fiber production. The objectives of this study were to: (1) determine under-productive areas within an agricultural field in a watershed using a single date; high resolution remote sensing and (2) examine impacts of growing bioenergy crops in the under-productive areas using hydrologic modeling in order to facilitate sustainable landscape design. Normalized difference indices (NDIs) were computed based on the ratio of all possible two-band combinations using the RapidEye and the National Agricultural Imagery Program images collected in summer 2011. A multiple regression analysis was performed using 10 NDIs and five RapidEye spectral bands. The regression analysis suggested that the red and near infrared bands and NDI using red-edge and near infrared that is known as the red-edge normalized difference vegetation index (RENDVI) had the highest correlation (R 2 = 0.524) with the reference yield. Although predictive yield map showed striking similarity to the reference yield map, the model had modest correlation; thus, further research is needed to improve predictive capability for absolute yields. Forecasted impact using the Soil and Water Assessment Tool model of growing switchgrass ( Panicum virgatum ) on under-productive areas based on corn yield thresholds of 3.1, 4.7, and 6.3 Mg·ha -1 showed reduction of tile NO 3 -N and sediment exports by 15.9%–25.9% and 25%–39%, respectively. Corresponding reductions in water yields ranged from 0.9% to 2.5%. While further research is warranted, the study demonstrated the integration of remote sensing and hydrologic modeling to quantify the multifunctional value of projected future landscape patterns in a context of sustainable bioenergy crop production.

09 BIOMASS FUELS↗

Governing Constraints of Chromium(VI) Formation from Chromium(III)-Bearing Minerals in Soils and Sediments

The potential for geogenic Cr(VI) contamination is vast, yet it is difficult to predict susceptible environments as groundwater Cr(VI) concentrations vary significantly, even within a given aquifer, due to physical and hydrologic heterogeneity. The physical structure of soils and sediments exerts a dominant control on Cr(VI) production by dictating the separation distance of reactive phases, the diffusion distance from Cr(VI) generation sites to advecting groundwater, and by influencing infiltration rates and porewater velocity. Here, we used a dual-pore domain model to investigate the relative control of these parameters on Cr(VI) production. The reaction distance between Cr(III)-bearing minerals and Mn oxides predominantly controls Cr(VI) export to advecting groundwater, while changes in diffusion distance between sites of Cr(VI) generation and advective flow channels generally have little impact on steady-state Cr(VI) concentrations. Changes in Cr(VI) diffusion distance can, however, increase the time required for groundwater Cr(VI) concentrations to reach a steady-state; thus, under fluctuating hydrologic and biogeochemical conditions, long diffusion distances still have the potential to suppress Cr(VI) supply to advecting water. Furthermore, we show that high porewater flow velocities effectively dilute Cr(VI) diffusing from soil/sediment aggregates, thus minimizing Cr(VI) concentrations relative to lower porewater velocities. The strong control that the physical/hydrologic parameters exert on Cr(VI) production appears to overwhelm the impact of Cr(III)-mineral solubility within soils and sediments.

Hausladen, Debra (ORCID:0000000342356294)↗

Policy Innovation and Governance for Irrigation Sustainability in the Arid, Saline San Joaquin River Basin

This paper provides a chronology and overview of events and policy initiatives aimed at addressing irrigation sustainability issues in the San Joaquin River Basin (SJRB) of California. Although the SJRB was selected in this case study, many of the same resource management issues are being played out in arid, agricultural regions around the world. The first part of this paper provides an introduction to some of the early issues impacting the expansion of irrigated agriculture primarily on the west side of the San Joaquin Valley and the policy and capital investments that were used to address salinity impairments to the use of the San Joaquin River (SJR) as an irrigation water supply. Irrigated agriculture requires large quantities of water if it is to be sustained, as well as supply water of adequate quality for the crop being grown. The second part of the paper addresses these supply issues and a period of excessive groundwater pumping that resulted in widespread land subsidence. A joint federal and state policy response that resulted in the facilities to import Delta water provided a remedy that lasted almost 50 years until the Sustainable Groundwater Management Act of 2014 was passed in the legislature to address a recurrence of the same issue. The paper describes the current state of basin-scale simulation modeling that many areas, including California, are using to craft a future sustainable groundwater resource management policy. The third section of the paper deals with unique water quality issues that arose in connection with the selenium crisis at Kesterson Reservoir and the significant threats to irrigation sustainability on the west side of the San Joaquin Valley that followed. The eventual policy response to this crisis was incremental, spanning two decades of University of California-led research programs focused on finding permanent solutions to the salt and selenium contamination problems constraining irrigated agriculture, primarily on the west side. Arid-zone agricultural drainage-induced water quality problems are becoming more ubiquitous worldwide. One policy approach that found traction in California is an innovative variant on the traditional Total Maximum Daily Load (TMDL) approach to salinity regulation, which has features in common with a scheme in Australia’s Hunter River Basin. The paper describes the real-time salinity management (RTSM) concept, which is geared to improving coordination of west side agricultural and wetland exports of salt load with east side tributary reservoir release flows to improve compliance with river salinity objectives. RTSM is a concept that requires access to continuous flow and electrical conductivity data from sensor networks located along the San Joaquin River and its major tributaries and a simulation model-based decision support designed to make salt load assimilative capacity forecasts. Web-based information dissemination and data sharing innovations are described with an emphasis on experience with stakeholder engagement and participation. The last decade has seen wide-scale, global deployment of similar technologies for enhancing irrigation agriculture productivity and protecting environmental resources.

54 ENVIRONMENTAL SCIENCES↗

Rapid Detection and Quick Characterization of African Swine Fever Virus Using the VolTRAX Automated Library Preparation Platform

African swine fever virus (ASFV) is the causative agent of a severe and highly contagious viral disease affecting domestic and wild swine. The current ASFV pandemic strain has a high mortality rate, severely impacting pig production and, for countries suffering outbreaks, preventing the export of their pig products for international trade. Early detection and diagnosis of ASFV is necessary to control new outbreaks before the disease spreads rapidly. One of the rate-limiting steps to identify ASFV by next-generation sequencing platforms is library preparation. Here, we investigated the capability of the Oxford Nanopore Technologies’ VolTRAX platform for automated DNA library preparation with downstream sequencing on Nanopore sequencing platforms as a proof-of-concept study to rapidly identify the strain of ASFV. Within minutes, DNA libraries prepared using VolTRAX generated near-full genome sequences of ASFV. Thus, our data highlight the use of the VolTRAX as a platform for automated library preparation, coupled with sequencing on the MinION Mk1C for field sequencing or GridION within a laboratory setting. These results suggest a proof-of-concept study that VolTRAX is an effective tool for library preparation that can be used for the rapid and real-time detection of ASFV.

60 APPLIED LIFE SCIENCES↗

A Model of Ice Wedge Polygon Drainage in Changing Arctic Terrain

As ice wedge degradation and the inundation of polygonal troughs become increasingly common processes across the Arctic, lateral export of water from polygonal soils may represent an important mechanism for the mobilization of dissolved organic carbon and other solutes. However, drainage from ice wedge polygons is poorly understood. We constructed a model which uses cross-sectional flow nets to define flow paths of meltwater through the active layer of an inundated low-centered polygon towards the trough. The model includes the effects of evaporation and simulates the depletion of ponded water in the polygon center during the thaw season. In most simulations, we discovered a strong hydrodynamic edge effect: only a small fraction of the polygon volume near the rim area is flushed by the drainage at relatively high velocities, suggesting that nearly all advective transport of solutes, heat, and soil particles is confined to this zone. Estimates of characteristic drainage times from the polygon center are consistent with published field observations.

54 ENVIRONMENTAL SCIENCES↗

Mapping Benthic Habitat Conditions and Seafloor Deposits using Sediment Profile Imaging and a Semiautomated Image Processing System

Objectives/Scope: Sediment profile imaging (SPI) technology characterizes in situ physical, geochemical, and biological seafloor features. SPI was required by Mexico’s Agency for Safety, Energy, and Environment in 2017 for environmental baseline surveys (EBS) of oil lease blocks in the southern Gulf of Mexico. Because of its ability to provide information on benthic community health and the distribution of very thin (down to the centimeter scale) layers of deposited materials, SPI technology is highly effective for mapping drill cuttings or drilling muds released around wellheads during exploration or production and documenting their ecological impacts. SPI technology has not been widely used in the oil and gas industry for EBS or other monitoring activities. A primary objective of this work is to improve the transparency and consistency of the SPI data generation and data management process. Methods, Procedures, Process: The SPI camera works like an inverted periscope and obtains an undisturbed 21x15-cm cross-sectional image of the upper sediment column. The camera is internally powered and can be deployed rapidly from a standard winch in depths to 4,000 m. Many stations can be sampled in a single day by “pogo-sticking” across a survey area. Sediment grain size, penetration depth, surface boundary roughness, natural and anthropogenic depositional layers, depth of the oxidized surface sediment layer, maximum biogenic mixing depth, and infaunal successional stage can be directly measured at sea or immediately following the cruise. Final SPI data sets can be provided within a few weeks of the survey. Results, Observations, Conclusions: Details on the features measured in SPI images and the underlying interpretive paradigms are presented. To standardize the SPI data generation process, Integral Consulting Inc. has developed 1) a semiautomated image analysis platform, and 2) a SPI data-specific database architecture that allows both numerical and non-numerical metrics to be incorporated into a standard database structure. An integrated, software-based SPI analysis platform has been developed that imports image files and metadata and provides a graphical user interface. The software automatically stores the data, which can then be reviewed for quality assurance, plotted, statistically analyzed, and mapped or exported to other platforms (e.g., Esri ArcGIS©) for further evaluation. Image processing algorithms have been developed using a combination of open-source and commercially available software packages (e.g., MATLAB® and OpenCV) to automatically quantify key parameters. Novel/Additive Information: SPI technology’s underutilization in the oil and gas industry may be in part due to a lack of standardization in the measurement of basic features in SPI images. A primary objective of this work is to develop a streamlined, standardized, and transparent process for generating and managing SPI data.

02 PETROLEUM↗

Ecohydrology of urban environments

Urban watersheds include a gradient of highly managed to unmanaged ecosystems that vary in vegetation cover, built and natural drainage systems, and impervious cover. A distinct difference to undeveloped ecosystems is the dominance of material and energy import and export, the disruption of natural catenae, the covariation of soils, terrain and canopy conditions. In this chapter, we discuss the distinct characteristics of urban ecohydrology compared to non-urban systems. We also investigate emergent principles of unmanaged watersheds that underscore the promotion of ecohydrological resilience, and the need to abstract and adapt these principles to support the goal-oriented restoration of impaired urban ecosystems.

42 ENGINEERING↗

Trans-Pacific transport and evolution of aerosols: spatiotemporal characteristics and source contributions

Aerosols in the middle and upper troposphere have a long enough lifetime for trans-Pacific transport from East Asia to North America to influence air quality on the west coast of the United States (US). Here, we conduct quasi-global simulations (180 °W–180 °E and 70 °S–75 °N) from 2010 to 2014 using an updated version of WRF-Chem (Weather Research and Forecasting model fully coupled with chemistry) to analyze the spatiotemporal characteristics and source contributions of trans-Pacific aerosol transport. We find that trans-Pacific total aerosols have a maximum mass concentration (about 15 µg m –3 ) in the boreal spring with a peak between 3 and 4 km above the surface around 40 °N. Sea salt and dust dominate the total aerosol mass concentration below 1 km and above 4 km, respectively. About 80.8 Tg of total aerosols (48.7 Tg of dust) are exported annually from East Asia, of which 26.7 Tg of aerosols (13.4 Tg of dust) reach the west coast of the US. Dust contributions from four desert regions in the Northern Hemisphere are analyzed using a tracer-tagging technique. About 4.9, 3.9, and 4.5 Tg year –1 of dust aerosol emitted from north Africa, the Middle East and central Asia, and East Asia, respectively, can be transported to the west coast of the US. The trans-Pacific aerosols dominate the column-integrated aerosol mass (~65.5 %) and number concentration (~80 %) over western North America. Radiation budget analysis shows that the inflow aerosols could contribute about 86.4 % (–2.91 W m –2 ) at the surface, 85.5 % (+1.36 W m –2 ) in the atmosphere, and 87.1 % (–1.55 W m –2 ) at the top of atmosphere to total aerosol radiative effect over western North America. However, near the surface in central and eastern North America, aerosols are mainly derived from local emissions, and the radiative effect of imported aerosols decreases rapidly. This study motivates further investigations of the potential impacts of trans-Pacific aerosols from East Asia on regional air quality and the hydrological cycle in North America.

54 ENVIRONMENTAL SCIENCES↗