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At least 1,351 records · Page 75

Study of impacts of two types of cellular aging on the yeast bud morphogenesis

Understanding the mechanisms of the cellular aging processes is crucial for attempting to extend organismal lifespan and for studying age-related degenerative diseases. Yeast cells divide through budding, providing a classical biological model for studying cellular aging. With their powerful genetics, relatively short cell cycle, and well-established signaling pathways also found in animals, yeast cells offer valuable insights into the aging process. Recent experiments suggested the existence of two aging modes in yeast characterized by nucleolar and mitochondrial declines, respectively. By analyzing experimental data, this study shows that cells evolving into those two aging modes behave differently when they are young. While buds grow linearly in both modes, cells that consistently generate spherical buds throughout their lifespan demonstrate greater efficacy in controlling bud size and growth rate at young ages. A three-dimensional multiscale chemical-mechanical model was developed and used to suggest and test hypothesized impacts of aging on bud morphogenesis. Experimentally calibrated model simulations showed that during the early stage of budding, tubular bud shape in one aging mode could be generated by locally inserting new materials at the bud tip, a process guided by the polarized Cdc42 signal. Furthermore, the aspect ratio of the tubular bud could be stabilized during the late stage as observed in experiments in this work. The model simulation results suggest that the localization of new cell surface material insertion, regulated by chemical signal polarization, could be weakened due to cellular aging in yeast and other cell types, leading to the change and stabilization of the bud aspect ratio.

Tsai, Kevin↗

Unsteady lifting-line theory as a singular-perturbation problem

Unsteady lifting-line theory is developed for a wing of large aspect ratio oscillating at low frequency in inviscid incompressible flow. The wing is assumed to have a rigid chord but a flexible span. Use of the method of matched asymptotic expansions reduces the problem from a singular integral equation to quadrature. The pressure field and airloads, for a prescribed wing shape and motion, are obtained in closed form as expansions in inverse aspect ratio. A rigorous definition of unsteady induced downwash is also obtained. Numerical calculations are presented for an elliptic wing in pitch and heave; compared with numerical lifting-surface theory, computation time is reduced significantly. The present work also identifies and resolves errors in the unsteady lifting line theory of James (1975), and points out a limitation in that of Van Holten (1975, 1976, 1977).

Ahmadi, A.↗

Reconnection in Compressible Plasmas: Extended Conversion Region

The classical Sweet-Parker approach to steady-state magnetic reconnection is extended into the regime of large resistivity (small magnetic Reynolds or Lundquist number) when the aspect ratio between the outflow and inflow scale, delta = d/L, approaches unity. In a previous paper the vicinity of the dissipation site ("diffusion region") was investigated. In this paper, the approach is extended to cover larger sites, in which the energy transfer and conversion is not confined to the diffusion region. Consistent with the results of Paper I, we find that increasing aspect ratio delta is associated with increasing compression, increasing reconnect ion rate for low Beta, but slightly decreasing rate for higher Beta, decreasing outflow speed, and increasing outflow magnetic field. These trends are stronger for lower Beta. Deviations from the traditional Sweet-Parker limit delta approaches 0 become significant for R(sub m) approx < 10, where R(sub m) is the magnetic Reynolds number (Lundquist number) based on the half-thickness of the current layer responsible for the Ohmic dissipation. They are also more significant for small gamma, that is, for increasing compressibility. In contrast to the results of Paper I, but consistent with earlier results for delta much < 1,nu(sub A) we find that in this limit the outflow speed is given by the Alfven speed nu(sub A) in the inflow region and the energy conversion is given by an even split of Poynting flux into enthalpy flux and bulk kinetic energy flux. However, with increasing delta the conversion to enthalpy flux becomes more and more dominant.

Birn, J.↗

Design aspects of long range supersonic LFC airplanes with highly swept wings

The achievement of natural LFC in SST configurations featuring externally braced, very highly swept, high structural aspect ratio wing planforms results in outstandingly high cruise L/D ratios while maintaining low sonic-boom overpressures. A conceptual design study has been conducted with a view to range capability maximization in SSTs. A three-body configuration employing a highly swept, strut-braced planform, in which a central fuselage and two smaller outboard bodies alleviate structural wing bending and torsion, is noted to allow further increases in wingspan and aspect ratio which commensurately reduce lift-induced wave-plus-vortex drag and volume-induced wave drag.

Pfenninger, Werner↗

Heat Transfer in a Complex Trailing Edge Passage for a High Pressure Turbine Blade - Part 1: Experimental Measurements: Experimental Measurements - Part 1

A combined experimental and computational study has been performed to investigate the detailed heat transfer coefficient distributions within a complex blade trailing edge passage. The experimental measurements are made using a steady liquid crystal thermography technique applied to one major side of the passage. The geometry of the trailing edge passage is that of a two-pass serpentine circuit with a sharp 180-degree turning region at the tip. The upflow channel is split by interrupted ribs into two major subchannels, one of which is turbulated. This channel has an average aspect ratio of roughly 14:1. The spanwise extent of the channel geometry includes both area convergence from root to tip, as well as taper towards the trailing edge apex. The average section Reynolds numbers tested in this upflow channel range from 55,000 to 98,000. The tip section contains a turning vane near the extreme comer. The downflow channel has an aspect ratio of about 5:1, and also includes convergence and taper. Turbulators of varying sizes are included in this channel also. Both detailed heat transfer and pressure distribution measurements are presented. The pressure measurements are incorporated into a flow network model illustrating the major loss contributors.

Bunker, Ronald S.↗

A Navier-Stokes study of shock-boundary layer interaction and flow separation inside a transonic compressor

A numerical study to evaluate a three-dimensional Navier-Stokes method as a tool to predict the detailed flowfield inside a low-aspect-ratio compressor at off-design rotor speed has been conducted. The flow field inside a state-of-the-art transonic compressor is used for the purpose of the evaluation. The experimental study shows that the rotor has higher peak efficiency at 90 percent rotor speed than at 100 percent rotor speed. The details of the flow structure inside the low-aspect-ratio compressor (three-dimensional shock structure, shock-boundary layer interaction, tip leakage vortex, etc.) and the overall aerodynamic performance at various operating conditions are numerically analyzed, and the results are compared with the available experimental data. The numerical results also indicate that the rotor has higher peak efficiency at 90 percent rotor speed than at 100 percent rotor speed. This is due to the reduced shock strength and the reduced interactions among passage shock, tip-clearance vortex and blade boundary layer.

Hah, Chunill↗

An asymptotic unsteady lifting-line theory with energetics and optimum motion of thrust-producing lifting surfaces

A low frequency unsteady lifting-line theory is developed for a harmonically oscillating wing of large aspect ratio. The wing is assumed to be chordwise rigid but completely flexible in the span direction. The theory is developed by use of the method of matched asymptotic expansions which reduces the problem from a singular integral equation to quadrature. The wing displacements are prescribed and the pressure field, airloads, and unsteady induced downwash are obtained in closed form. The influence of reduced frequency, aspect ratio, planform shape, and mode of oscillation on wing aerodynamics is demonstrated through numerical examples. Compared with lifting-surface theory, computation time is reduced significantly. Using the present theory, the energetic quantities associated with the propulsive performance of a finite wing oscillating in combined pitch and heave are obtained in closed form. Numerical examples are presented for an elliptic wing.

Ahmadi, A. R.↗

Influence of Clay size on corrosion protection by Clay nanocomposite thin films

In this work, the influence of clay platelet size on the corrosion barrier performance of highly-aligned polymer clay nanocomposite (PCN) thin films was examined. Layer-by-layer (LbL) deposition of alternating branched polyethylenimine (PEI) and either laponite (LAP), montromorillonite (MMT) or vermiculite (VMT) clay platelets were assembled on mild steel plates to obtain 20 bilayer (BL) films and cross-linked using glutaraldehyde after deposition. The clay platelets were chosen based on their aspect ratio, approximately 30:1, 400:1, and 2000:1, respectively. Electrochemical impedance spectroscopy of the coated steel plates during immersion showed corrosion rates and coating permeability followed LAP > MMT > VMT for up to 7 days of exposure in 0.6 M NaCl. The PEI/VMT films, ~250 nm thick, slowed corrosion by a factor of >1000 compared to bare steel. The results support the premise that high aspect ratio clay platelets can improve the corrosion barrier efficacy of LbL PCN films by decreasing film permeability and provide exceptional protection to steel in saline environments compared to other thin multilayer coatings and pretreatments.

36 MATERIALS SCIENCE↗

Miniature Scroll Pumps Fabricated by LIGA

Miniature scroll pumps have been proposed as roughing pumps (low - vacuum pumps) for miniature scientific instruments (e.g., portable mass spectrometers and gas analyzers) that depend on vacuum. The larger scroll pumps used as roughing pumps in some older vacuum systems are fabricated by conventional machining. Typically, such an older scroll pump includes (1) an electric motor with an eccentric shaft to generate orbital motion of a scroll and (2) conventional bearings to restrict the orbital motion to a circle. The proposed miniature scroll pumps would differ from the prior, larger ones in both design and fabrication. A miniature scroll pump would include two scrolls: one mounted on a stationary baseplate and one on a flexure stage (see figure). An electromagnetic actuator in the form of two pairs of voice coils in a push-pull configuration would make the flexure stage move in the desired circular orbit. The capacitance between the scrolls would be monitored to provide position (gap) feedback to a control system that would adjust the drive signals applied to the voice coils to maintain the circular orbit as needed for precise sealing of the scrolls. To minimize power consumption and maximize precision of control, the flexure stage would be driven at the frequency of its mechanical resonance. The miniaturization of these pumps would entail both operational and manufacturing tolerances of <1 m. Such tight tolerances cannot be achieved easily by conventional machining of high-aspect-ratio structures like those of scroll-pump components. In addition, the vibrations of conventional motors and ball bearings exceed these tight tolerances by an order of magnitude. Therefore, the proposed pumps would be fabricated by the microfabrication method known by the German acronym LIGA ( lithographie, galvanoformung, abformung, which means lithography, electroforming, molding) because LIGA has been shown to be capable of providing the required tolerances at large aspect ratios.

Wiberg, Dean↗

Compact Assumption Applied to the Monopole Term of Farassat's Formulations

Farassat's formulations provide an acoustic prediction at an observer location provided a source surface, including motion and flow conditions. This paper presents compact forms for the monopole term of several of Farassat's formulations. When the physical surface is elongated, such as the case of a high aspect ratio rotorcraft blade, compact forms can be derived which are shown to be a function of the blade cross sectional area by reducing the computation from a surface integral to a line integral. The compact forms of all formulations are applied to two example cases: a short span wing with constant airfoil cross section moving at three forward flight Mach numbers and a rotor at two advance ratios. Acoustic pressure time histories and power spectral densities of monopole noise predicted from the compact forms of all the formulations at several observer positions are shown to compare very closely to the predictions from their non-compact counterparts. A study on the influence of rotorcraft blade shape on the high frequency portion of the power spectral density shows that there is a direct correlation between the aspect ratio of the airfoil and the error incurred by using the compact form. Finally, a prediction of pressure gradient from the non-compact and compact forms of the thickness term of Formulation G1A shows that using the compact forms results in a 99.6% improvement in computation time, which will be critical when noise is incorporated into a design environment.

Lopes, Leonard V.↗

Mesoscale convection in the clouds of Venus

A theory explaining the high aspect ratios for cloud level convection in the Venusian atmosphere is presented. The apparent flatness of large-scale convection cells in the Venusian clouds is accounted for by anisotropic eddy diffusion and radiative transfer effects. Horizontal eddy diffusivities must be at least ten-fold greater than vertical diffusivities. Anisotropy ratios greater than or approximately equal to 1,000 are sufficient to explain the flattening in cases where the vertical eddy diffusivity is greater than or approximately equal to 100,000 sq cm/s and the effects of radiative transfer are negligible. For vertical diffusivity greater than or approximately equal to 100,000 sq cm/s, radiative transfer contributes to the flattening. Radiative transfer alone can not account for the apparent aspect ratios, as this would require vertical heat diffusivities large enough to give a nonphysically high value of convective heat transport.

Covey, C. C.↗

A Note on the Drag Due to Lift of Delta Wings at Mach Numbers up to 2.0

In order to indicate the effects of Reynolds number and other variables on the drag due to lift of delta wings for Mach numbers up to 2.0, the results of several investigations of wing-body combinations having plane delta wings with aspect ratios from 2 to 4 have been assembled for comparison and brief analysis. The effects of Reynolds number, leading-edge radius, and thickness ratio could generally be correlated with Reynolds number based on the leading-edge radius as a parameter. The effects of leading-edge Reynolds number on drag due to lift were large at Mach numbers less than 0.25. However, with increases in Mach number, the effects decreased and were almost negligible at a Mach number of 2.0. and trimming were large, as would be expected. The effects of aspect ratio and trimming were large, as would be expected. It was indicated at least for subsonic and transonic speeds that improvement in the drag due to lift might be obtained from wing modifications designed to inhibit flow separation.

Robert S. Osborne↗

Transonic-Wind-Tunnel Tests of the Aerodynamic Characteristics of a 0.15-Scale Model of the North American Aviation 255-Inch Fin-Stabilized External Store, Coord No. AF-AM-4

An investigation has been made in the Langley 8-foot transonic tunnels on the aerodynamic characteristics of a 0.15-scale model of the North American Aviation 255-inch fin-stabilized external store over a maximum Mach number range of 0.60 to 1.2 and on the effects of mounting lugs, of fin orientation, of fin aspect ratio, and of fixed-transition. The Reynolds number (based on a body length of 37.50 inches) varied from 9.8 x 10(exp 6) to 13.1 x 10(exp 6). The results indicate that the static margin of the finned store at low lift coefficients was only 9 percent of body length at subsonic Mach numbers and was reduced to zero at a Mach number of 1.0, Increasing the fin aspect ratio from 1.82 to 2.41 increased the subsonic static margin to 18 percent and provided a minimum margin of 9 percent near a Mach number of l.O. Store mounting lugs or fin orientation had only small effects on the aerodynamic characteristics of the basic store.

Fischetti, Thomas L.↗

Multimachine analysis of intermittent fluctuations in the scrape-off layer of magnetically confined fusion plasmas

Far scrape-off layer fluctuations, also known as blobs/filaments, are compared for the first time across six tokamaks: Alcator C-Mod, DIII-D, TCV, KSTAR, MAST, and MAST-U, under the context of stochastic modeling in Ohmic and low confinement mode scenarios. In this model, which well describes these fluctuations, measurements from Langmuir probes are modeled as a superposition of uncorrelated, two-sided exponential temporal pulses. The key parameters of this model are the mean waiting times between consecutive pulses, the pulse duration times and the mean of the pulse amplitudes. The study examines the influence of line-averaged density, plasma current, magnetic field and aspect ratio. The mean amplitudes and pulse waiting times increase with the line-averaged density across devices, while the pulse duration times remain constant. Whereas the variation in waiting times is gradual across the density scan, the mean amplitudes increase abruptly as the density profile broadens and flattens for Alcator C-Mod. The blob waiting times decrease with increasing plasma current and the toroidal magnetic field, while they increase with aspect ratio for conventional tokamaks. The duration times follow the same trends as the waiting times in these parameters but vary more slowly, resulting in the trends in the waiting times dominating the intermittency level of the fluctuations.

70 PLASMA PHYSICS AND FUSION TECHNOLOGY↗

Shapes of Venusian 'pancake' domes imply episodic emplacement and silicic composition

The main evidence available for constraining the composition of the large circular 'pancake' domes on Venus is their gross morphology. Laboratory simulations using polyethylene glycol show that the height to diameter (aspect) ratios of domes of a given total volume depend critically on whether their extrusion was continuous or episodic, with more episodes leading to greater cooling and taller domes. Thus without observations of their emplacement, the compositions of Venusian domes cannot be uniquely constrained by their morphology. However, by considering a population of 51 Venusian domes to represent a sampling of many stages during the growth of domes with comparable histories, and by plotting aspect ratio versus total volume, we find that the shapes of the domes are most consistent with episodic emplacement. On Earth this mode of dome growth is found almost exclusively in lavas of dacite to rhyolite composition, strengthening earlier inferences about the presence of evolved magmas on Venus.

Fink, Jonathan H.↗

Time-dependent scenario modeling for the ST-E1 fusion power plant

ST-E1 is a low aspect ratio fusion power plant being designed by Tokamak Energy targeting 1.5 GW of fusion power. Characterization of the ST-E1 flat-top scenario is described elsewhere McNamara et al (2026 Nucl. Fusion 66 086008); here we focus on addressing the question of how to ramp-up the ST-E1 plasma from an initial state following breakdown and flux-surface formation to the target flat-top state. Being low-aspect ratio, the available solenoid flux of ST-E1 is limited. Therefore, particular consideration is placed on developing ramp-up scenarios that predominantly use inductive flux provided by external vertical field coils. Through time-dependent modeling with METIS, we show that this is possible when the ramp-up is performed at relatively high plasma density: although auxiliary current drive efficiency is reduced, this is significantly outweighed by (1) higher electron-ion collisional equilibration, (2) higher fusion power once ions become sufficiently hot, (3) higher poloidal beta for increased vertical-field flux, and (4) potentially favorable exhaust compatibilities. Ultimately, we show the target ST-E1 flat-top performance can be reached after a ramp-up period lasting 150 s using less than 40 Vs of solenoid flux (with vertical field providing ∼ 90 Vs of flux). The sensitivity to model assumptions are presented, with the general observation that deleterious effects can be mitigated through minor alterations of the auxiliary power temporal waveform and/or total auxiliary power level. The impact of a solenoid and the auxiliary power mix (electron cyclotron heating only versus electron and ion cyclotron heating) on the ST-E1 ramp-up success are also discussed in appendices. On this latter topic, we show that the effect of direct-ion heating during ramp-up is obscured by the uncertainty in the pedestal dynamics, identifying a clear line of future work required to make a definite decision on the ST-E1 auxiliary power mix.

current ramp-up↗

Experimental evidence for non-proportional growth of large craters

Evidence from laboratory impact experiments is indicating that increasing crater aspect ratios (diameter:depth) can result from increasing both velocity and projectile size without invoking unusual impactor conditions. An extensive data base of experimental impact cratering was analyzed for a variety of impactors and impact velocities for low strength targets. These data indicate a change in cratering efficiency that appears to be related to the onset of projectile deformation or rupture. When all projectile types and sizes are considered, one finds two contrasting relationships between crater aspect ratio and impactor parameter. These relationships are briefly considered.

Schultz, Peter H.↗

The EET Horizontal Tails Investigation and the EET Lateral Controls Investigation

In the energy efficient transport (EET) Horizontal Tails Investigation, aerodynamic data were measured for five different horizontal tails on a full span model with a wide body fuselage. Three of the horizontal tails were low tail configurations and two were T tail configurations. All tails were tested in conjunction with two wings, a current wide body wing and a high aspect ratio supercritical wing. Local downwash angles and dynamic pressures in the vicinity of the tails were measured using a yaw head rake. The results provide a comparison of the aerodynamic characteristics of the two wing configurations at trimmed conditions for Mach numbers between 0.60 and 0.90. In the EET Lateral Controls Investigation, the control effectiveness of a conventional set of lateral controls was measured over a Mach number range from 0.60 to 0.90 on a high aspect ratio supercritical wing semispan model. The conventional controls included a high speed aileron, a low speed aileron, and six spoiler segments. The wing was designed so that the last 25% of the chord is removable to facilitate testing of various control systems. The current status and an indication of the data obtained in these investigations are presented.

Jacobs, P. F.↗