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All sourcesNASA NTRSDOE OSTI
DOE OSTI2020

Carrier-assisted One-pot Sample Preparation for Targeted Proteomics Analysis of Small Numbers of Human Cells

Protein analysis of small numbers of human cells is primarily achieved by targeted proteomics with antibody-based immunoassays, which have inherent limitations (e.g., low multiplex and unavailability of antibodies for new proteins). Mass spectrometry (MS)-based targeted proteomics has emerged as an alternative because it is antibody-free, high multiplex, and has high specificity and quantitation accuracy. Recent advances in MS instrumentation make MS-based targeted proteomics possible for multiplexed quantification of highly abundant proteins in single cells. However, there is a technical challenge for effective processing of single cells with minimal sample loss for MS analysis. To address this issue, we have recently developed a convenient protein carrier-assisted one-pot sample preparation coupled with liquid chromatography (LC) - selected reaction monitoring (SRM) termed cLC-SRM for targeted proteomics analysis of small numbers of human cells. This method capitalizes on using the combined excessive exogenous protein as a carrier and low-volume one-pot processing to greatly reduce surface adsorption losses as well as high-specificity LC-SRM to effectively address the increased dynamic concentration range due to the addition of exogeneous carrier protein. Its utility has been demonstrated by accurate quantification of most moderately abundant proteins in small numbers of cells (e.g., 10-100 cells) and highly abundant proteins in single cells. The easy-to-implement features and no need for specific devices make this method readily accessible to most proteomics laboratories. In this study, we have provided a detailed protocol for cLC-SRM analysis of small numbers of human cells including cell sorting, cell lysis and digestion, LC-SRM analysis, and data analysis. Further improvements in detection sensitivity and sample throughput are needed towards targeted single-cell proteomics analysis. We anticipate that cLC-SRM will be broadly applied to biomedical research and systems biology with the potential of facilitating precision medicine.

60 APPLIED LIFE SCIENCES↗
NASA NTRS1978

NASA patent abstracts bibliography: A continuing bibliography. Section 1: Abstracts (supplement 13)

This bibliography is issued in two sections: Section 1 - Abstracts, and Section 2 - Indexes. This issue of the Abstract Section cites 161 patents and applications for patent introduced into the NASA scientific and technical information system during the period January 1978 through June 1978. Each entry consists of a citation, an abstract, and in most cases, a key illustration selected from the patent or application for patent.

Source record↗
NASA NTRS2000

SeaWiFS Postlaunch Calibration and Validation Analyses

The effort to resolve data quality issues and improve on the initial data evaluation methodologies of the SeaWiFS Project was an extensive one. These evaluations have resulted, to date, in three major reprocessings of the entire data set where each reprocessing addressed the data quality issues that could be identified up to the time of the reprocessing. Three volumes of the SeaWiFS Postlaunch Technical Report Series (Volumes 9, 10, and 11) are needed to document the improvements implemented since launch. Volume 10 continues the sequential presentation of postlaunch data analysis and algorithm descriptions begun in Volume 9. Chapter 1 of Volume 10 describes an absorbing aerosol index, similar to that produced by the Total Ozone Mapping Spectrometer (TOMS) Project, which is used to flag pixels contaminated by absorbing aerosols, such as, dust and smoke. Chapter 2 discusses the algorithm being used to remove SeaWiFS out-of-band radiance from the water-leaving radiances. Chapter 3 provides an itemization of all significant changes in the processing algorithms for each of the first three reprocessings. Chapter 4 shows the time series of global clear water and deep-water (depths greater than 1,000m) bio-optical and atmospheric properties (normalized water-leaving radiances, chlorophyll, atmospheric optical depth, etc.) based on the eight-day composites as a check on the sensor calibration stability. Chapter 5 examines the variation in the derived products with scan angle using high resolution data around Hawaii to test for residual scan modulation effects and atmospheric correction biases. Chapter 6 provides a methodology for evaluating the atmospheric correction algorithm and atmospheric derived products using ground-based observations. Similarly, Chapter 7 presents match-up comparisons of coincident satellite and in situ data to determine the accuracy of the water-leaving radiances, chlorophyll a, and K(490) products.

Hooker, Stanford B.↗
NASA NTRS2003

MC-1 Engine Valves, Lessons Learned

Many lessons were learned during the development of the valves for the MC-1 engine. The purpose of this report is to focus on a variety of issues related to the engine valves and convey the lessons learned. This paper will not delve into detailed technical analysis of the components. None of the lessons learned are new or surprising, but simply reinforce the importance of addressing the details of the design early, at the component level. The Marshall Space Flight Center (MSFC), Huntsville, Alabama developed the MC-1 engine, a LOX / FW-1, 60,000 pound thrust engine. This engine was developed under the Low Cost Boost Technology office at MSFC and proved to be a very successful project for the MSFC Propulsion team and the various subcontractors working the development of the engine and its components.

Laszar, John↗
NASA NTRS2004

Deployment Process, Mechanization, and Testing for the Mars Exploration Rovers

NASA's Mar Exploration Rover (MER) robotic prospectors were produced in an environment of unusually challenging schedule, volume, and mass restrictions. The technical challenges pushed the system s design towards extensive integration of function, which resulted in complex system engineering issues. One example of the system's integrated complexity can be found in the deployment process for the rover. Part of this process, rover "standup", is outlined in this paper. Particular attention is given to the Rover Lift Mechanism's (RLM) role and its design. Analysis methods are presented and compared to test results. It is shown that because prudent design principles were followed, a robust mechanism was created that minimized the duration of integration and test, and enabled recovery without perturbing related systems when reasonably foreseeable problems did occur. Examples of avoidable, unnecessary difficulty are also presented.

Iskenderian, Ted↗
NASA NTRS2004

Deployment process, mechanization, and testing for the Mars Exploration Rovers

NASA’s Mar Exploration Rover (MER) robotic prospectors were produced in an environment of unusually challenging schedule, volume, and mass restrictions. The technical challenges pushed the system’s design towards extensive integration of function, which resulted in complex system engineering issues. One example of the system’s integrated complexity can be found in the deployment process for the rover. Part of this process, rover “standup”, is outlined in this paper. Particular attention is given to the Rover Lift Mechanism’s (RLM) role and its design. Analysis methods are presented and compared to test results. It is shown that because prudent design principles were followed, a robust mechanism was created that minimized the duration of integration and test, and enabled recovery without perturbing related systems when reasonably foreseeable problems did occur. Examples of avoidable, unnecessary difficulty are also presented.

Iskenderian, Ted C.↗
DOE OSTI2017

Design and implementation of HuREX analysis supporting interface - 171

Human error is recognized as one of the main causes to affect to the socio-technical system including nuclear power plant. Therefore, reducing human error through human reliability analysis (HRA) is a critical issue. Moreover, sufficient and reliable human performance data collection is a prerequisite for ensuring the safety of nuclear power plants. Korea Atomic Energy Research Institute developed the HuREX (Human Reliability data Extraction) framework to collect and analyze the responses of human operators from simulator training records of nuclear power plant. Thus, the development and computer software interfaces of the database are essential to efficiently support human reliability analysis. In this study, OPERA database was developed in accordance with the following process. First, the essential data required for the HRA analysis (e.g., plant data, procedures, system and equipment info, operating crews, results of simulator experiments, and so forth) was stored in the database. In addition, standardized procedures and related items were stored in the database to support HRA quantification. A data structure was developed to store crew responses conducted by operators to cope with an emergency situation during simulator experiments. In addition, various interfaces that escalate efficiency of the HuREX applications were developed. The HuREX analysis support interface was developed with HuREX Video Analyzer for observation of simulator collection data (e.g., audio-visual records, plant parameters, operator's action logs) and HuREX Data Analyzer for analysis of operator's conducted task. By using the OPERA database and HuREX analysis support interface developed through this research, maximizing the efficiency of human reliability analysis based on simulator training data. (authors)

22 GENERAL STUDIES OF NUCLEAR REACTORS↗
NASA NTRS2010

NASA Aerospace Flight Battery Program: Recommendations for Technical Requirements for Inclusion in Aerospace Battery Procurements

This NASA Aerospace Flight Battery Systems Working Group was chartered within the NASA Engineering and Safety Center (NESC). The Battery Working Group was tasked to complete tasks and to propose proactive work to address battery related, agency-wide issues on an annual basis. In its first year of operation, this proactive program addressed various aspects of the validation and verification of aerospace battery systems for NASA missions. Studies were performed, issues were discussed and in many cases, test programs were executed to generate recommendations and guidelines to reduce risk associated with various aspects of implementing battery technology in the aerospace industry. This document contains Part 2 - Volume I: Recommendations for Technical Requirements for Inclusion in Aerospace Battery Procurements of the program's operations.

Jung, David S.↗
DOE OSTI2021

Supply Chain Sustainability Analysis of Renewable Hydrocarbon Fuels via Indirect Liquefaction, Ex Situ Catalytic Fast Pyrolysis, Hydrothermal Liquefaction, Combined Algal Processing, and Biochemical Conversion: Update of the 2020 State-of-Technology Cases

The Department of Energy’s (DOE) Bioenergy Technologies Office (BETO) aims to develop and deploy technologies to transform renewable biomass resources into commercially viable, high-performance biofuels, bioproducts, and biopower through public and private partnerships (U.S. Department of Energy, 2016). BETO and its national laboratory teams conduct in-depth techno-economic assessments (TEA) of biomass feedstock supply and logistics and conversion technologies to produce biofuels. There are two general types of TEAs: A design case outlines a target case (future projection) for a particular biofuel pathway. It enables identification of data gaps and research and development needs and provides goals and benchmarks against which technology progress is assessed. A state of technology (SOT) analysis assesses progress within and across relevant technology areas based on actual results at current experimental scales relative to technical targets and cost goals from design cases, and includes technical, economic, and environmental criteria as available. In addition to developing a TEA for a pathway of interest, BETO also performs a supply chain sustainability analysis (SCSA). The SCSA takes the life-cycle analysis approach that BETO has been supporting for about 20 years. It enables BETO to identify energy consumption, environmental, and sustainability issues that may be associated with biofuel production. Approaches to mitigate these issues can then be developed. Additionally, the SCSA allows for comparison of energy and environmental impacts across biofuel pathways in BETO’s research and development portfolio. This technical report describes the SCSAs for the production of renewable hydrocarbon transportation fuels via a range of conversion technologies in the 2020 SOTs: (1) renewable high octane gasoline (HOG) via indirect liquefaction (IDL) of woody lignocellulosic biomass (note that the IDL pathway in this SCSA represents the syngas conversion design [Harris et al. 2021]); (2) renewable gasoline (RG) and diesel (RD) blendstocks via ex situ catalytic fast pyrolysis of woody lignocellulosic biomass [Abhijit et al. 2021]; (3) RD via hydrothermal liquefaction (HTL) of wet sludge from a wastewater treatment plant; (4) renewable hydrocarbon fuels via biochemical conversion of herbaceous lignocellulosic biomass (Davis et al. 2021; Lin et al. 2021); (5) renewable diesel via HTL of a blend of algae (Davis and Klein, 2021) and woody biomass (Hartley et al. 2020); and (6) renewable diesel via combined algae processing (CAP) (Wiatrowski and Davis, 2021). This technical report focuses on the environmental performance of these six biofuel production pathways in their 2020 SOT cases. The results of these renewable hydrocarbon fuel pathways in these SCSA analyses update those for the respective 2019 SOT cases (Cai et al. 2020). They also provide an opportunity to examine the impact of technology improvements in both biomass feedstock production and biofuel production that have been achieved in 2020 SOTs on the sustainability performance of these renewable transportation fuels. The SCSA results also reflect updates to Argonne National Laboratory’s Greenhouse gases, Regulated Emissions, and Energy use in Technologies (GREET®) model, which was released in October 2020 (Wang et al. 2020). These GREET updates include the production of natural gas, electricity, and petroleum-based fuels that can influence biofuels’ supply chain greenhouse gas (GHG) (CO 2 , CH 4 , and N 2 O) emissions, water consumption, and air pollutant emissions. GHG emissions, water consumption, and nitrogen oxides (NO x ) emissions are the main sustainability metrics assessed in this analysis. In this analysis, we define water consumption as the amount of water withdrawn from a freshwater source that is not returned (or returnable) to a freshwater source at the same level of quality. Life-cycle fossil energy consumption and net energy balance, which is the life-cycle fossil energy consumption deducted from the renewable biofuel energy produced, are also assessed.

09 BIOMASS FUELS↗
DOE OSTI2023

Supply Chain Sustainability Analysis of Renewable Hydrocarbon Fuels via Hydrothermal Liquefaction, Combined Algal Processing, and Biochemical Conversion: Update of the 2022 State-of-Technology Cases

The Department of Energy's (DOE) Bioenergy Technologies Office (BETO) aims to develop and deploy technologies to transform renewable biomass resources into commercially viable, high-performance biofuels, bioproducts, and biopower through public and private partnerships. BETO and its national laboratory teams conduct in-depth techno-economic assessments (TEA) of biomass feedstock supply and logistics and conversion technologies to produce biofuels. There are two general types of TEAs: A design case outlines a target case (future projection) for a particular biofuel pathway. It informs R&D priorities by identifying areas in need of improvement, tracks sustainability impact of R&D, and provides goals and benchmarks against which technology progress is assessed. A state of technology (SOT) analysis assesses progress within and across relevant technology areas based on actual results at current experimental scales relative to technical targets and cost goals from design cases, and includes technical, economic, and environmental criteria as available. In addition to developing a TEA for a pathway of interest, BETO also performs a supply chain sustainability analysis (SCSA). The SCSA takes the life-cycle analysis approach that BETO has been supporting for over 20 years. It enables BETO to identify energy consumption, environmental, and sustainability issues that may be associated with biofuel production. Approaches to mitigating these issues can then be developed. Additionally, the SCSA allows for comparison of energy and environmental impacts across biofuel pathways in BETO's research and development portfolio. This technical report describes the SCSAs for the production of renewable hydrocarbon transportation fuels via a range of conversion technologies in the 2022 SOTs: (1) renewable hydrocarbon fuels via hydrothermal liquefaction (HTL) of wet sludge from a wastewater treatment plant; (2) renewable hydrocarbon fuels via biochemical conversion of herbaceous lignocellulosic biomass; (3) renewable hydrocarbon fuels via HTL of an algae/woody biomass blend; and (4) renewable hydrocarbon fuels via combined algae processing (CAP).

09 BIOMASS FUELS↗
NASA NTRS1992

Aeronomical modeling of the outer planets

The purpose is twofold: to report the programmatic issues of the project as to accomplishments and anticipated work statement for the next six months and to report the technical findings of the project. From the programmatic point of view the study was a clear success. Four talks were given on the work: (1) a talk on electron Bremsstrahlung X ray production at the annual American Astronomical Society, Division of Planetary Studies meeting in October of 1990 in Charlottesville, Virginia; (2) a poster on proton precipitation at the May, 1991 American Geophysical Union in Baltimore, Maryland; (3) an invited paper on multispectral time dependent modeling at the International Union of Geodosy and Geomagnetism in Vienna in August of 1991; and (4) a paper at the annual Division of Planetary Studies of the American Astronomical Society held in Palo Alto in November of 1991 entitled 'Jovian Bremsstrahlung X Rays: A Ulysses Prediction' which predicted the Jovian auroral X ray flux that should be measured by the Ulysses Gamma Ray Burst experiment during the Ulysses spacecraft's closest encounter with Jupiter in February 1992. The Ulysses' prediction paper generated much interest from people studying the Jovian aurora and from experimenters on the Ulysses spacecraft. As a result of this interest two things happened: (1) a paper of the same title was submitted and accepted for publication in the January issue of the Geophysical Research Letters; and (2) a massive observing campaign was organized to provide supporting ultraviolet and infrared observations at the time of the Ulysses encounter. This observational interest allowed personnel at the Southwest Research Institute (SwRI) (Alan Stern, PI; Hunter Waite Co-I) to obtain director's discretionary time on the Hubble Space Telescope to support the Ulysses encounter by obtaining ultraviolet observations. Once the multiple wavelength observations are obtained in February, the auroral model developed under this project will be used to analyze the data with hopes of providing new insight into the physical processes responsible for the Jovian aurora.

Waite, J. Hunter, Jr.↗
DOE OSTI2017

Validation of the Computational Fluid Dynamics Method using the Aboveground Configuration of the Dry Cask Simulator

Dry cask applicants submit their spent nuclear fuel dry storage and transportation cask designs to the U.S. Nuclear Regulatory Commission (NRC) for certification under Title 10 of the Code of Federal Regulations (10 CFR) Part 72, 'Licensing Requirements for the Independent Storage of Spent Nuclear Fuel, High-Level Radioactive Waste, and Reactor-Related Greater Than Class C Waste'. The NRC staff performs its technical review of these designs in accordance with 10 CFR Part 72 and NUREG-1536, 'Standard Review Plan for Spent Fuel Dry Storage Systems at a General License Facility,' Revision 1, issued July 2010. To ensure that the cask and fuel material temperatures of the dry cask storage system remain within the allowable limits or criteria for normal, off-normal, and accident conditions, the NRC staff performs a thermal review as part of the technical review. Recent applications increasingly have used thermalhydraulic analyses using computational fluid dynamics (CFD) codes (e.g., ANSYS FLUENT) to demonstrate the adequacy of the thermal design. The NRC performs validation studies of the FLUENT CFD code to assist it in making regulatory decisions to ensure adequate protection for storage and transportation casks. Recent advances in dry storage cask designs have significantly increased the maximum thermal load allowed in a cask in part by increasing the efficiency of internal conduction pathways and by increasing the internal convection through greater canister helium pressure. In efforts to further validate these designs, the NRC in conjunction with the Department of Energy and Sandia National Laboratories (SNL) are conducting an experiment to capture the effects of elevated helium pressures and accurately portray the external convection of aboveground and belowground canister dry cask systems.

12 MANAGEMENT OF RADIOACTIVE AND NON-RADIOACTIVE W↗
DOE OSTI2018

United States Nuclear Manufacturing Infrastructure Assessment

This report provides a review and assessment of the existing U.S. infrastructure capabilities to manufacture on a commercial scale, the major components and unique materials required by the various U.S. designs for advanced nuclear reactors and small modular reactors (SMRs). The approach was to compare the needs of SMRs and advanced reactors against the capability of U.S. manufacturers to ascertain gaps that could inhibit U.S. industrial support for deployment of SMRs or advanced reactors. This report focused on the reactor plant designs being developed by NuScale Power (the NuScale Power Module), TerraPower (both the Traveling Wave Reactor and the Molten Chloride Fast Reactor to a limited extent), and X-energy (the Xe-100). To gather the information, MPR visited each of these companies and selected candidate suppliers to tour their facilities and conduct in-person interviews. Information was also obtained by telephone interviews, internet research, and literature review of technical reports. The overarching conclusion from this study is that the U.S. has existing capability or can readily develop capability to support and sustain most, but not all, aspects of commercial deployment of advanced reactors and SMRs. The greatest concerns for capability gaps in the U.S. infrastructure for supply of components for SMRs and advanced reactors are associated with reactor pressure vessels, steam generators, and fuel fabrication. Foreign vendors can supply reactor pressure vessels and steam generators. Issues with fuel fabrication are associated with uranium enrichment and development of fabrication methods for the innovative fuel concepts planned for advanced reactors. The technical capabilities of U.S. manufacturers appear satisfactory with the possible exceptions noted above. However, the capacity of the existing U.S. manufacturing infrastructure may be insufficient for a high rate of construction. Manufacturers contacted as part of this study indicated a willingness to expand capacity if sufficient orders are in place. The review of U.S. infrastructure included a detailed review of capabilities in many different processes including forging, tube drawing, machining, fabrication, and testing. In addition, MPR researched the advanced manufacturing processes for additive manufacturing (i.e., 3D printing) and powder metallurgy - hot isostatic pressing. Reactor plant designers and candidate suppliers are planning to rely on traditional processes for the initial plants. If advanced manufacturing processes are developed and accepted by the nuclear industry, these processes may be used in the future. In the immediate term, ongoing research (much of which is funded by DOE) is necessary to develop and refine advanced manufacturing methods. This report includes several recommendations for DOE that will advance deployment of SMRs and advanced reactors from a manufacturing perspective and other areas identified during the course of this project.

36 MATERIALS SCIENCE↗
NASA NTRS2005

Engineering Lessons Learned and Systems Engineering Applications

Systems Engineering is fundamental to good engineering, which in turn depends on the integration and application of engineering lessons learned and technical standards. Thus, good Systems Engineering also depends on systems engineering lessons learned from within the aerospace industry being documented and applied. About ten percent of the engineering lessons learned documented in the NASA Lessons Learned Information System are directly related to Systems Engineering. A key issue associated with lessons learned datasets is the communication and incorporation of this information into engineering processes. Systems Engineering has been defined (EINIS-632) as "an interdisciplinary approach encompassing the entire technical effort to evolve and verify an integrated and life-cycle balanced set of system people, product, and process solutions that satisfy customer needs". Designing reliable space-based systems has always been a goal for NASA, and many painful lessons have been learned along the way. One of the continuing functions of a system engineer is to compile development and operations "lessons learned" documents and ensure their integration into future systems development activities. They can produce insights and information for risk identification identification and characterization. on a new project. Lessons learned files from previous projects are especially valuable in risk

Gill, Paul S.↗
DOE OSTI2026

Thriving in the Carbon-Aware Market: How to Account for Emissions in the Era of Carbon-Centered Trade Policies

Emerging global policies, such as the European Union's enacted Carbon Border Adjustment Mechanism and similar policies under development in Canada, Australia and the United Kingdom, will place a premium on goods traded into their territories with higher embedded emissions than those produced domestically. U.S. manufacturers could stand to benefit from such policies; given the investments U.S. industry has made to reduce the energy and emission intensities of its operations. For example, the overall GHG intensity of U.S. steel production in 2019 was ~0.96 t CO2/t steel, less than half that of China (~1.97 t CO2/t steel), and bested only by Italy. To realize these benefits, transparent, accurate, interoperable and accepted embedded emissions accounting and calculation methods are required. Achieving this requires overcoming challenges related to data availability, boundary definitions, and product definitions among others, both at individual facilities as well as through value chains. We will present technical findings on methodology considerations and data-availability constraints for determining the emissions of traded goods, using steel as a pilot and leveraging publicly available data. Issues such as determining the appropriate scope for emissions accounting, implications of the specificity of product chosen, emissions allocation in multi-product facilities, and enumeration of emissions for products manufactured across multiple facilities will be discussed. By sharing the results of our efforts, we aim to inform the development and execution of embedded emissions accounting methods from a technical perspective such that U.S. manufacturers can thrive in emerging global markets.

29 ENERGY PLANNING, POLICY, AND ECONOMY↗
NASA NTRS1992

NSSDC Conference on Mass Storage Systems and Technologies for Space and Earth Science Applications, volume 2

This report contains copies of nearly all of the technical papers and viewgraphs presented at the NSSDC Conference on Mass Storage Systems and Technologies for Space and Earth Science Application. This conference served as a broad forum for the discussion of a number of important issues in the field of mass storage systems. Topics include the following: magnetic disk and tape technologies; optical disk and tape; software storage and file management systems; and experiences with the use of a large, distributed storage system. The technical presentations describe, among other things, integrated mass storage systems that are expected to be available commercially. Also included is a series of presentations from Federal Government organizations and research institutions covering their mass storage requirements for the 1990's.

Kobler, Ben↗
DOE OSTI2018

Cyberspace, Information Strategy and International Security (Workshop Summary)

In recent years, the Center for Global Security Research has hosted a number of events to inform strategic thought on key areas of concern to national security and laboratory planning. This was the first dedicated workshop that CGSR has hosted seeking to convene a community of experts around issues of cybersecurity and Internet governance as they pertain to national security. The goal of this work was to bridge policy, academic, military, technical and other expert communities that often have limited contact with each other’s concerns and specialized knowledge. This workshop brought together over 80 experts from government, military, national labs, academic institutions, think tanks, the private sector, and civil society and hailing from 10 countries. While focusing on the national security challenges and military strategy emerging in and through cyberspace, the workshop aimed to address the cross-cutting interests and concerns of different stakeholders in the development and future governance of cyberspace, including those of the private sector, and civilian publics. To this end, the first day of the workshop focused particularly on issues directly relevant to military strategy in the cyber domain, while the second day addressed questions bridging national security and military concerns and their connections to the domestic and international politics of Internet governance. Topics discussed included the evolving cyber strategies of the U.S., U.S. allies and potential adversaries, as well as the complex characteristics of the cyber domain, the potential for deterrence in or through cyberspace, the domain’s escalation risks, and the ways in which the “dual use” nature of much of the underlying technology of cyberspace connects actions in the domain with broader questions of global Internet governance. Issues of online disinformation and information warfare and the unique conceptual tensions and governance challenges posed by these forms of conflict were addressed. The workshop also examined the roles and interests of different stakeholders in addressing cybersecurity challenges, as well as the possibility of norms, international law, and other potential mechanisms of constraint.

97 MATHEMATICS AND COMPUTING↗
NASA NTRS1979

Preliminary Report: Issues in selection and training for long duration space flight

Based on previous experience with crew selection, three important avenues of consideration for future missions are discussed: technical qualifications and expertise; medical fitness and ability to tolerate the various conditions of space; and psychological considerations including personality structure, motivation, intelligence, leadership potential, group compatibility, etc. Primary emphasis was given to the psychological considerations.

Akins, F. R.↗