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Membrane Design Principles for Ion-Selective Electrodialysis: An Analysis for Li/Mg Separation
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SPICE_MARS: A Process Synthesis Framework for Membrane-Assisted Reactive Separations
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Design of Gas Separation Processes Using Type II Porous Liquids as Physical Solvents
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Reactive Extraction Process for Separating 2,3-Butanediol from Fermentation Broth
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Improving Absorbent-Enhanced Ammonia Separation For Efficient Small-Scale Ammonia Synthesis
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Fieldable Microfluidic Platform for Separation and Assay of U and Pu from Fission Samples in Environmental Matrices
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A Solid-State Support for Separating Astatine-211 from Bismuth
Increasing access to the short-lived α-emitting radionuclide astatine-211 ( 211 At) has the potential to advance targeted α-therapeutic treatment of disease and to solve challenges facing the medical community. For example, there are numerous technical needs associated with advancing the use of 211 At in targeted α-therapy, e.g., improving 211 At chelates, developing more effective 211 At targeting, and characterizing in vivo 211 At behavior. There is an insufficient understanding of astatine chemistry to support these efforts. The chemistry of astatine is one of the least developed of all elements on the periodic table, owing to its limited supply and short half-life. Increasing access to 211 At could help address these issues and advance understanding of 211 At chemistry in general. Here, we contribute an extraction chromatographic processing method that simplifies 211 At production in terms of purification. It utilizes the commercially available Pre-Filter resin to rapidly (<1.5 h) isolate 211 At from irradiated bismuth targets (Bi decontamination factors ≥876 000), in reasonable yield (68–55%) and in a form that is compatible for subsequent in vivo study. We are excited about the potential of this procedure to address 211 At supply and processing/purification problems.
Optimal Tuning Perspective of Range-Separated Double Hybrid Functionals
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