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All sourcesNASA NTRSDOE OSTI
NASA NTRS1998

High-Temperature Magnetic Bearings Being Developed for Gas Turbine Engines

Magnetic bearings are the subject of a new NASA Lewis Research Center and U.S. Army thrust with significant industry participation, and cooperation with other Government agencies. The NASA/Army emphasis is on high-temperature applications for future gas turbine engines. Magnetic bearings could increase the reliability and reduce the weight of these engines by eliminating the lubrication system. They could also increase the DN (diameter of bearing times the rpm) limit on engine speed and allow active vibration cancellation systems to be used, resulting in a more efficient, "more electric" engine. Finally, the Integrated High Performance Turbine Engine Technology (IHPTET) program, a joint Department of Defense/industry program, identified a need for a high-temperature (1200 F) magnetic bearing that could be demonstrated in their Phase III engine. This magnetic bearing is similar to an electric motor. It has a laminated rotor and stator made of cobalt steel. Wound around the stator's circumference are a series of electrical wire coils which form a series of electric magnets that exert a force on the rotor. A probe senses the position of the rotor, and a feedback controller keeps it centered in the cavity. The engine rotor, bearings, and casing form a flexible structure with many modes. The bearing feedback controller, which could cause some of these modes to become unstable, could be adapted to varying flight conditions to minimize seal clearances and monitor the health of the system.

Kascak, Albert F.↗
DOE OSTI2020

Species-Specific Duplication Event Associated with Elevated Levels of Nonstructural Carbohydrates in Sorghum bicolor

Simple sugars are the essential foundation to plant life, and thus, their production, utilization, and storage are highly regulated processes with many complex genetic controls. Despite their importance, many of the genetic and biochemical mechanisms remain unknown or uncharacterized. Sorghum, a highly productive, diverse C4 grass important for both industrial and subsistence agricultural systems, has considerable phenotypic diversity in the accumulation of nonstructural sugars in the stem. We use this crop species to examine the genetic controls of high levels of sugar accumulation, identify genetic mechanisms for the accumulation of nonstructural sugars, and link carbon allocation with iron transport. We identify a species-specific tandem duplication event controlling sugar accumulation using genome-wide association analysis, characterize multiple allelic variants causing increased sugar content, and provide further evidence of a putative neofunctionalization event conferring adaptability in Sorghum bicolor. Comparative genomics indicate that this event is unique to sorghum which may further elucidate evolutionary mechanisms for adaptation and divergence within the Poaceae. Furthermore, the identification and characterization of this event was only possible with the continued advancement and improvement of the reference genome. The characterization of this region and the process in which it was discovered serve as a reminder that any reference genome is imperfect and is in need of continual improvement.

59 BASIC BIOLOGICAL SCIENCES↗
NASA NTRS1998

Cytoskeletal role in the transition from compensated to decompensated hypertrophy during adult canine left ventricular pressure overloading

Increased microtubule density causes cardiocyte contractile dysfunction in right ventricular (RV) pressure-overload hypertrophy, and these linked phenotypic and contractile abnormalities persist and progress during the transition to failure. Although more severe in cells from failing than hypertrophied RVs, the mechanical defects are normalized in each case by microtubule depolymerization. To define the role of increased microtubule density in left ventricular (LV) pressure-overload hypertrophy and failure, in a given LV we examined ventricular mechanics, sarcomere mechanics, and free tubulin and microtubule levels in control dogs and in dogs with aortic stenosis both with LV hypertrophy alone and with initially compensated hypertrophy that had progressed to LV muscle failure. In comparing initial values with those at study 8 weeks later, dogs with hypertrophy alone had a very substantial increase in LV mass but preservation of a normal ejection fraction and mean systolic wall stress. Dogs with hypertrophy and associated failure had a substantial but lesser increase in LV mass and a reduction in ejection fraction, as well as a marked increase in mean systolic wall stress. Cardiocyte contractile function was equivalent, and unaffected by microtubule depolymerization, in cells from control LVs and those with compensated hypertrophy. In contrast, cardiocyte contractile function in cells from failing LVs was quite depressed but was normalized by microtubule depolymerization. Microtubules were increased only in failing LVs. These contractile and cytoskeletal changes, when assayed longitudinally in a given dog by biopsy, appeared in failing ventricles only when wall stress began to increase and function began to decrease. Thus, the microtubule-based cardiocyte contractile dysfunction characteristic of pressure-hypertrophied myocardium, originally described in the RV, obtains equally in the LV but is shown here to have a specific association with increased wall stress.

Non-NASA Center↗
NASA NTRSDate not supplied

Dynamic Assurance of Autonomous Systems through Ground Control Software

Assurance cases are being increasingly acknowledged as a way to build trust in complex systems with autonomous capabilities [1]. An assurance case is a comprehensive, defensible, and valid justification that a system will function as intended for the specific mission and operating environment. Such justifications for systems with autonomous capabilities are often based on various probabilistic quantifications [2]. Due to the dynamic nature of the environmental conditions in which these systems operate, as well as the changing nature of the autonomous systems themselves, these probabilistic quantifications cannot be simply estimated once during design time. Rather, they need to be continually evaluated during systems operations to ensure that the assurance case justifications are valid. We refer to the assurance case that combines both the static and dynamic elements as a Dynamic Assurance Case (DAC). Such complex systems with autonomous capabilities are often deployed with a Ground Control Software (GCS) component to enable remote operation. Whether the system is composed of a single unit or a fleet of units, deployed distributed or in remote environments, GCS acts as a window into the behavior of the deployed system. It receives telemetry from the system, issues commands to the system and provides various functionalities to visualize the system performance. We propose a dynamic assurance framework where the GCS acts as a relay between the autonomous system and its DAC. GCS can be used to measure both unit-specific as well as system-wide probabilistic quantifications using the incoming telemetry. We embed these quantifications throughout the DAC as variables that can be updated by external sources. We use the GCS to periodically update these variables, which allows us to continually evaluate the formally defined assurance case justifications. We demonstrate our dynamic assurance framework in the NASA Ames project Troupe1 that aims at developing a fleet of rovers capable of au- tonomously mapping their environment. The rovers work cooperatively, each collecting data for different parts of the environment. Each rover runs an identical core Flight System (cFS) [4] application. Troupe1 uses OpenC3 Cosmos [5] as the ground system, and AdvoCATE [3] to capture the system DAC. We show how we can measure both rover-specific and system-wide quantifications in Cosmos using its Ruby scripting editor and pass them into the DAC modelled in AdvoCATE. Then, we show how these incoming variables can be embedded in different parts of the DAC and how effects of their updates can be observed

Irfan Sljivo↗
NASA NTRS2022

Run Time Assurance for Electric Vertical Takeoff and Landing Aircraft

NASA is conducting research to demonstrate and evaluate the application of Run Time Assurance (RTA) as a means to assure safety in Electric Vertical Takeoff and Landing (eVTOL) aircraft with highly automated or autonomous flight capability supervised by a single onboard pilot. The work described in this report demonstrates an application of RTA and examines the implications for design and analysis of aircraft functions and systems; aircraft safety hazards; safety assurance; development assurance; and pilot tasks and performance. This research effort also seeks to assess the efficacy of the combined application of traditional Functional Hazard Analysis (FHA) and the more modern System Theoretic Process Analysis (STPA) techniques to perform hazard analyses on aircraft with complex automated and autonomous systems and an onboard pilot. During the research effort we developed architectural designs of two alternate eVTOL aircraft, generally following the process characterized in the SAE standards ARP4754 and ARP4761. The design has focused on the control architectures of these aircraft, which are identical except that one incorporates RTA techniques to reduce the criticality of some key software components. Artifacts of this process include a taxonomy of aircraft-level functions, aircraft-level architecture diagrams, aircraft-level functional hazard assessments (AFHA), function allocations onto aircraft systems and subsystems, functional block diagrams for a select set of control-related functions, and system-level functional hazard assessments (SFHA) for those functions. This project has highlighted the notion that DAL D is something of a sweet spot for low-confidence controllers in an RTA-based design. Among the many activities described in DO-178C, the activities related to requirement verifiability, algorithmic accuracy, and test coverage can be the most challenging for the kinds of advanced control techniques that may be desirable in novel UAM designs, such as adaptive control, machine-learning, artificial intelligence, numerical search, and Monte Carlo based algorithms. Moreover, the standard requires that development teams demonstrate that errors leading to unacceptable failure conditions have been removed from the software. The RTA architecture, which cordons off the low-confidence function, makes it much easier to show this for these kinds of algorithms. With regard to the use of STPA and FHA as complementary hazard analysis techniques, our research effort led us to the conclusion that STPA should be used to derive requirements for hardware and software systems and/or components. Also, STPA is a natural complement to other processes in ARP4754A involving design studies and iteration.

Run-time assurance↗
DOE OSTI2023

Design and License Application Development for TRISO-X (Final Scientific Technical Report)

This is the final progress report submitted by X-energy, LLC (XE) to the Department of Energy in support of cooperative agreement DE-NE0008745. This report provides a high-level summary of the work performed during the entire period of performance, running from August 24, 2018 – August 22, 2022. This span of time covers the original 3-year award and a one year no-cost extension. There were five tasks within this project: (1) project management, (2) systems engineering and studies, (3) TRISO-X Facility design, (4) facility license application development, and (5) support to application review. Detailed reporting during execution of the project was provided by a total of 16 quarterly reports, voluntary monthly update presentations, and annual summary presentations. Technical work products include 103 X-energy technical reports, 38 subcontractor (Centrus technical reports), 75 Nuclear Criticality Safety Evaluations/Calculation reports, and 272 miscellaneous design documents (e.g., Engineering Service Orders, Engineering Component Specifications, Procedures, Guidelines/Policies, Design and Interface Requirements documents, and Drawings). All 29 of the X Energy milestones/deliverables were met early or on time and are archived in the DOE Office of Nuclear Energy’s Program Information Control System: Nuclear Energy under Fiscal Year 2018, Work Breakdown Structure F.OA – Industry FOA FY 2018 Awards, F.03 – X-Energy TRISO-X Project. All other work products are available to DOE upon request.

11 NUCLEAR FUEL CYCLE AND FUEL MATERIALS↗
NASA NTRS1975

Flight investigation of rotor/vehicle state feedback

The feasibility of using control feedback or rotor tip-path-plane motion or body state as a means of altering rotor and fuselage response in a prescribed manner was investigated to determine the practical limitations of in-flight utilization of a digital computer which conditions and shapes rotor flapping and fuselage state information as feedback signals, before routing these signals to the differential servo actuators. The analysis and test of various feedback schemes are discussed. Test results show that a Kalman estimator routine which is based on only the first harmonic contributions of blade flapping yields tip-path-plane coefficients which are adequate for use in feedback systems, at speeds up to 150 kts.

Briczinski, S. J.↗
NASA NTRS2003

An Automated, Low Mass, Low Power Drill for Acquiring Subsurface Samples of Ground Ice for Astrobiology Studies on Earth and on Mars

As a project that is part of NASA s Astrobiology Technology & Instrument Development Program (ASTID), we are developing a low mass (approx.20kg) drill that will be operated without drilling fluids and at very low power levels (approx.60 watts electrical) to access and retrieve samples from permafrost regions of Earth and Mars. The drill, designed and built as a joint effort by NASA JSC and Baker-Hughes International, takes the form of a down-hole unit attached to a cable so that it can, in principle, be scaled easily to reach significant depths. A parallel laboratory effort is being carried out at UC Berkeley to characterize the physics of dry drilling under martian conditions of pressure, temperature and atmospheric composition. Data from the UCB and JSC laboratory experiments are being used as input to a drill simulation program which is under development to provide autonomous control of the drill. The first Arctic field test of the unit is planned for May 2004. A field expedition to Eureka on Ellesmere Island in Spring 2003 provided an introduction for several team members to the practical aspects of drilling under Arctic conditions. The field effort was organized by Wayne Pollard of McGill University and Christopher McKay of NASA ARC. A conventional science drill provided by New Zealand colleagues was used to recover ground ice cores for analysis of their microbial content and also to develop techniques using tracers to track the depth of penetration of contamination from the core surface into the interior of the samples.

Briggs, G. A.↗
NASA NTRS1966

Nuclear Rocket Technology Conference

The Lewis Research Center has a strong interest in nuclear rocket propulsion and provides active support of the graphite reactor program in such nonnuclear areas as cryogenics, two-phase flow, propellant heating, fluid systems, heat transfer, nozzle cooling, nozzle design, pumps, turbines, and startup and control problems. A parallel effort has also been expended to evaluate the engineering feasibility of a nuclear rocket reactor using tungsten-matrix fuel elements and water as the moderator. Both of these efforts have resulted in significant contributions to nuclear rocket technology. Many successful static firings of nuclear rockets have been made with graphite-core reactors. Sufficient information has also been accumulated to permit a reasonable Judgment as to the feasibility of the tungsten water-moderated reactor concept. We therefore consider that this technoIogy conference on the nuclear rocket work that has been sponsored by the Lewis Research Center is timely. The conference has been prepared by NASA personnel, but the information presented includes substantial contributions from both NASA and AEC contractors. The conference excludes from consideration the many possible mission requirements for nuclear rockets. Also excluded is the direct comparison of nuclear rocket types with each other or with other modes of propulsion. The graphite reactor support work presented on the first day of the conference was partly inspired through a close cooperative effort between the Cleveland extension of the Space Nuclear Propulsion Office (headed by Robert W. Schroeder) and the Lewis Research Center. Much of this effort was supervised by Mr. John C. Sanders, chairman for the first day of the conference, and by Mr. Hugh M. Henneberry. The tungsten water-moderated reactor concept was initiated at Lewis by Mr. Frank E. Rom and his coworkers. The supervision of the recent engineering studies has been shared by Mr. Samuel J. Kaufman, chairman for the second day of the conference, and Mr. Roy V. Humble. Dr. John C. Eward served as general chairman for the conference.

Source record↗
NASA NTRSDate not supplied

Crew Health and Performance (CHP) Technology Roadmaps

The Environmental Control and Life Support System (ECLSS) – Crew Health and Performance (CHP) Systems Capability Leadership Team (SCLT) is a community of practice (not a funded program) sponsored by Headquarters to develop, retain, and infuse the ECLSS and CHP capabilities necessary to enable the human exploration of the Moon and Mars through the integration and empowerment of experts across NASA, other government agencies, commercial industry, and academia. The goals of the SCLT are as follows: Use the Architecture Definition Document use cases and functions to identify gaps in NASA’s current technological capabilities to meet Agency objectives and develop strategies and roadmaps for closing such gaps Make technical/strategic recommendations on ECLSS and CHP technology development efforts and investments for PPBE, acquisition strategies, and leveraging NASA’s critical capabilities Establish key performance parameters and participate in key program and project reviews Maintain cognizance of relevant ECLSS and CHP national and international technology activities in government, industry, and academia, specifically, emerging innovations and technologies, trends, and opportunities Coordinate with commercial and international partners to identify areas of mutual interest and cooperation Support future mission and system architecture studies for human exploration This document is intended to be a comprehensive overview of the strategic development plans, or Roadmaps, of key technologies and capabilities identified by the SCLT. Each Roadmap is organized by Capability Gap as the gap name and number appears in STARPort, follows a fiscal year timeline, and displays any additional information on milestones, decision points, or important details on the right-hand side of the page. The Roadmaps should be used to facilitate discussion, decision making, and planning for programs and development projects, but are not expected to accurately depict the details and statuses of the projects and tasks appearing within the plans.

Human Health and Performance↗
DOE OSTI2026

Unalakleet Microgrid Optimization for Tribal Community Resilience

The Unalakleet Microgrid Optimization Project aimed to strengthen the reliability and efficiency of the isolated electric power system that serves the Tribal community of Unalakleet, Alaska. The community relies entirely on a local wind-diesel microgrid, consisting of four 475 kW diesel generators and six 100 kW wind turbines, to provide electricity to approximately 745 residents and Tribal facilities. Because Unalakleet is not on a road system and is located nearly 400 miles from the nearest major power grid, maintaining a resilient and efficient local energy system is critical. The scope of this project included upgrading a portion of the transmission line between the wind farm and the power plant to increase voltage and reduce line losses, along with modernizing the Supervisory Control and Data Acquisition (SCADA) system to improve monitoring, control, and data management of the power system. These upgrades were designed to increase wind energy utilization, reduce diesel fuel consumption by tens of thousands of gallons annually, and improve overall grid stability. By allowing more of the community’s electricity to be supplied by local renewable wind resources, the project was designed to lower operating costs, reduce dependence on imported fuel, and strengthen the long-term resilience of the power system. These improvements represent an important step toward the community’s long-term energy vision of expanding renewable generation, incorporating energy storage, and eventually achieving “diesels-off” operation, where essential Tribal loads are powered primarily by local renewable resources.

17 WIND ENERGY↗
NASA NTRS1987

Incremental planning to control a blackboard-based problem solver

To control problem solving activity, a planner must resolve uncertainty about which specific long-term goals (solutions) to pursue and about which sequences of actions will best achieve those goals. A planner is described that abstracts the problem solving state to recognize possible competing and compatible solutions and to roughly predict the importance and expense of developing these solutions. With this information, the planner plans sequences of problem solving activities that most efficiently resolve its uncertainty about which of the possible solutions to work toward. The planner only details actions for the near future because the results of these actions will influence how (and whether) a plan should be pursued. As problem solving proceeds, the planner adds new details to the plan incrementally, and monitors and repairs the plan to insure it achieves its goals whenever possible. Through experiments, researchers illustrate how these new mechanisms significantly improve problem solving decisions and reduce overall computation. They briefly discuss current research directions, including how these mechanisms can improve a problem solver's real-time response and can enhance cooperation in a distributed problem solving network.

Durfee, E. H.↗
NASA NTRS1994

Lessons learned supporting onboard solid-state recorders

With the advance of semiconductor technology, Solid-State Recorders (SSR) have matured and been accepted as primary onboard data storage devices. Their high reliability, simpler interface and control, and high flexibility have made the SSR's a superb choice in today's spacecraft design. While there are many benefits, the use of SSR's may also add significant complexity to ground data systems. For instance, real-time and playback data may be interleaved into the same data stream, making data sequencing and time ordering difficult. Stored data may be played back out of time order, increasing processing load significantly. Data may also be played back after being sorted by Virtual Channels in the SSR, potentially creating bursts in packet rates that exceed the real-time processing capabilities of the ground systems. This paper presents a summary of lessons learned through the efforts in supporting a number of NASA's missions that employ SSR's. It describes various problems encountered through the design process, and their potential impact on ground system performance, resources, and cost. Recommended approaches to minimizing the impact are demonstrated by examples. The discussion leads to the conclusion that the use of SSR's demands an even higher level of cooperation between spacecraft and ground system designers in order to build the most cost effective end-to-end system.

Shi, Jeff↗
NASA NTRS2006

Notional Airspace Operations Demonstration Plan

The airspace operations demonstration (AOD) is intended to show that the Access 5 Step 1 functional requirements can be met. The demonstration will occur in two phases. The initial on-range phase will be carried out in restricted airspace to demonstrate the cooperative collision avoidance (CCA) functional requirements and to provide risk-reduction for the AOD by allowing the test team to rehearse some elements of the demonstration mission. The CCA system to be used in these flights is based on Automatic Dependent Surveillance-Broadcast (ADS-B) which is a commercially-available system by which airplanes constantly broadcast their current position and altitude to other aircraft and ground resources over a dedicated radio datalink. The final phase will occur in the national airspace (NAS) and will be the formal demonstration of the remainder of the proposed functional requirements. The general objectives of the AOD are as follows: (1) Demonstrate that the UAS can aviate in the NAS (2) Demonstrate that the UAS can navigate in the NAS (3) Demonstrate that the UAS can communicate with the NAS (4) Demonstrate that the UAS can perform selected collision avoidance functions in the NAS (5) Demonstrate that the UAS can evaluate and avoid weather conflicts in the NAS (6) Demonstrate that the UAS can provide adequate command and control in the NAS In addition to the stated objectives, there are a number of goals for the flight demonstration. The demo can be accomplished successfully without achieving these goals, but these goals are to be used as a guideline for preparing for the mission. The goals are: (1) Mission duration of at least 24 hours (2) Loiter over heavy traffic to evaluate the data block issue identified during the Access 5 Airspace Operations Simulations (3) Document the contingency management process and lessons learned (4) Document the coordination process for Ground Control Stations (GCS) handoff (5) Document lessons learned regarding the process of flying in the NAS Preliminary planning for a notional mission to achieve the objectives and goals has been prepared. The planning is intended to serve as a guide for detailed planning of the AOD.

Trongale, Nicholas A.↗
NASA NTRS2016

COBALT: A GN&C Payload for Testing ALHAT Capabilities in Closed-Loop Terrestrial Rocket Flights

The COBALT (CoOperative Blending of Autonomous Landing Technology) payload is being developed within NASA as a risk reduction activity to mature, integrate and test ALHAT (Autonomous precision Landing and Hazard Avoidance Technology) systems targeted for infusion into near-term robotic and future human space flight missions. The initial COBALT payload instantiation is integrating the third-generation ALHAT Navigation Doppler Lidar (NDL) sensor, for ultra high-precision velocity plus range measurements, with the passive-optical Lander Vision System (LVS) that provides Terrain Relative Navigation (TRN) global-position estimates. The COBALT payload will be integrated onboard a rocket-propulsive terrestrial testbed and will provide precise navigation estimates and guidance planning during two flight test campaigns in 2017 (one open-loop and closed- loop). The NDL is targeting performance capabilities desired for future Mars and Moon Entry, Descent and Landing (EDL). The LVS is already baselined for TRN on the Mars 2020 robotic lander mission. The COBALT platform will provide NASA with a new risk-reduction capability to test integrated EDL Guidance, Navigation and Control (GN&C) components in closed-loop flight demonstrations prior to the actual mission EDL.

Carson, John M., III↗
NASA NTRS2001

ECC Ozonesonde Reliability, Observations, and Comparisons with Satellite Ozone Instruments

Electrochemical Concentration Cell (ECC) ozone instruments depend on the quality of care exercised in their pre-flight preparation. The ozone-measuring project conducted at Goddard Space Flight Center's Wallops Flight Facility uses a number of mechanisms designed to inspect the ECC for anomalies that may interfere with the reception of valid ozone profiles. Complete electronic testing of the instrument, individually and when coupled to its radiosonde has led to exceptional monitoring of ozone for detecting long-term atmospheric changes. A number of factors are considered when preparing an ECC instrument for flight. These basically are specific calibrations of pump efficiency, volumetric flow rate, temperature of the air entering the pump, and background current. The concentration of the potassium iodide solution is also important. Wallops is the only site using a UV photometer (Dasibi) to compare ECC ozone output at various concentrations of ozone that allows adjustment to be made to offsets that may appear in the balloon-borne instrument prior to release. All of the above procedures allow identification of potential problems before release of the ECC instrument. Procedures followed at Wallops also are employed in Brazil, and Ascension Island where NASA has cooperative agreements in place to obtain ozonesondes data. All ECC instruments are prepared 3-4 weeks prior to the day of observation. We will briefly describe the instrumental tests employed. These tests have included simultaneous dual observations to compare the effect of different solution concentrations, comparison of sensors of different manufacturers, and comparisons with surface- and space-based instrumentation such as the Dobson Spectrophotometer and satellites. Vertical profiles of ozone from Arctic, mid-latitudes, and Antarctica will be discussed. Although not unusual, the data reveals ozone structure that correlate well with typical atmospheric temperatures and possibly relative humidity. Finally, vertical ozone distribution, compared with remotely measured ozone from lidar and satellite, will be discussed. Specific comparisons between ECC and HALOE measurements, integrated ECC total ozone overburden with the EP-TOMS and the Dobson, as well as comparisons with lidar are discussed. Results show agreement and some disagreement between the in situ measurements of the ECC and the remote instruments. We postulate reasons for the differences, or biases, which in spite of the excellent ECC quality control during pre-flight preparation and data analysis processes, may be due to uncertainties in both measuring systems.

Schmidlin, F. J.↗
NASA NTRS2010

Permissible Exposure Level for Lunar Dusts: Gaps are Closing

Space faring nations plan to return human explorers to the moon within the next decade. Experience during the Apollo flights suggests that lunar dust will invariably get into the habitat where the finest portion (less than 5 micrometers) could be inhaled by the crew before it is cleared from the atmosphere. NASA is developing a database from which a 6-month, episodic exposure standard for lunar dust can be set. Three kinds of moon dust were prepared from a parent sample of Apollo 14 regolith #14003,96. Our goal was to prepare each type of dust sample with a mean diameter less than 2 m, which is suitable for instillation into the lungs of rats. The three samples were prepared as follows: separation from the parent sample using a fluidized bed, grinding using a jet mill grinder, or grinding with a ball-mill grinder. Grinding simulated restoration of surface activation of dust expected to occur at the surface of the moon on native lunar dust. We used two grinding methods because they seemed to produce different modes of activation. The effects of grinding were preserved by maintaining the dust in ultra-pure nitrogen until immediately before it was placed in suspension for administration to rats. The dust was suspended in physiological saline with 10% Survanta, a lung surfactant. Rats were given intratrachael instillations of the dust suspension at three doses. In addition to the three moon dusts (A, C and E), we instilled the same amount of a negative control (TiO2, B) and a highly-toxic, positive control (quartz, D). These additional mineral dusts were selected because they have well-established and very different permissible exposure levels (PELs). Our goal was to determine where lunar dusts fit between these extremes, and then estimate a PEL for each lunar dust. We evaluated many indices of toxicity to the lung. The figure shows the changes in lactate dehydrogenase (LDH), a marker of cell death, for the five dusts. Benchmark dose software (Version 2.1.2) from the Environmental Protection Agency was used to estimate the 10% effect levels (BMD(sub 10)) using five models. The best-fitting model was used to estimate the optimal BMD(sub 10) (table)

James, John T.↗
NASA NTRS2008

Standardizing Interfaces for External Access to Data and Processing for the NASA Ozone Product Evaluation and Test Element (PEATE)

NASA's traditional science data processing systems have focused on specific missions, and providing data access, processing and services to the funded science teams of those specific missions. Recently NASA has been modifying this stance, changing the focus from Missions to Measurements. Where a specific Mission has a discrete beginning and end, the Measurement considers long term data continuity across multiple missions. Total Column Ozone, a critical measurement of atmospheric composition, has been monitored for'decades on a series of Total Ozone Mapping Spectrometer (TOMS) instruments. Some important European missions also monitor ozone, including the Global Ozone Monitoring Experiment (GOME) and SCIAMACHY. With the U.S.IEuropean cooperative launch of the Dutch Ozone Monitoring Instrument (OMI) on NASA Aura satellite, and the GOME-2 instrumental on MetOp, the ozone monitoring record has been further extended. In conjunction with the U.S. Department of Defense (DoD) and the National Oceanic and Atmospheric Administration (NOAA), NASA is now preparing to evaluate data and algorithms for the next generation Ozone Mapping and Profiler Suite (OMPS) which will launch on the National Polar-orbiting Operational Environmental Satellite System (NPOESS) Preparatory Project (NPP) in 2010. NASA is constructing the Science Data Segment (SDS) which is comprised of several elements to evaluate the various NPP data products and algorithms. The NPP SDS Ozone Product Evaluation and Test Element (PEATE) will build on the heritage of the TOMS and OM1 mission based processing systems. The overall measurement based system that will encompass these efforts is the Atmospheric Composition Processing System (ACPS). We have extended the system to include access to publically available data sets from other instruments where feasible, including non-NASA missions as appropriate. The heritage system was largely monolithic providing a very controlled processing flow from data.ingest of satellite data to the ultimate archive of specific operational data products. The ACPS allows more open access with standard protocols including HTTP, SOAPIXML, RSS and various REST incarnations. External entities can be granted access to various modules within the system, including an extended data archive, metadata searching, production planning and processing. Data access is provided with very fine grained access control. It is possible to easily designate certain datasets as being available to the public, or restricted to groups of researchers, or limited strictly to the originator. This can be used, for example, to release one's best validated data to the public, but restrict the "new version" of data processed with a new, unproven algorithm until it is ready. Similarly, the system can provide access to algorithms, both as modifiable source code (where possible) and fully integrated executable Algorithm Plugin Packages (APPs). This enables researchers to download publically released versions of the processing algorithms and easily reproduce the processing remotely, while interacting with the ACPS. The algorithms can be modified allowing better experimentation and rapid improvement. The modified algorithms can be easily integrated back into the production system for large scale bulk processing to evaluate improvements. The system includes complete provenance tracking of algorithms, data and the entire processing environment. The origin of any data or algorithms is recorded and the entire history of the processing chains are stored such that a researcher can understand the entire data flow. Provenance is captured in a form suitable for the system to guarantee scientific reproducability of any data product it distributes even in cases where the physical data products themselves have been deleted due to space constraints. We are currently working on Semantic Web ontologies for representing the various provenance information. A new web site focusing on consolidating informaon about the measurement, processing system, and data access has been established to encourage interaction with the overall scientific community. We will describe the system, its data processing capabilities, and the methods the community can use to interact with the standard interfaces of the system.

Tilmes, Curt A.↗