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At least 1,315 records · Page 73
All sourcesNASA NTRSDOE OSTI
NASA NTRS1985

Hormone Purification by Isoelectric Focusing

Various ground-based research approaches are being applied to a more definitive evaluation of the natures and degrees of electroosmosis effects on the separation capabilities of the Isoelectric Focusing (IEF) process. A primary instrumental system for this work involves rotationally stabilized, horizontal electrophoretic columns specially adapted for the IEF process. Representative adaptations include segmentation, baffles/screens, and surface coatings. Comparative performance and development testing are pursued against the type of column or cell established as an engineering model. Previously developed computer simulation capabilities are used to predict low-gravity behavior patterns and performance for IEF apparatus geometries of direct project interest. Three existing mathematical models plus potential new routines for particular aspects of simulating instrument fluid patterns with varied wall electroosmosis influences are being exercised.

Bier, M.↗
NASA NTRS1987

Spacelab Life Sciences flight experiments: an integrated approach to the study of cardiovascular deconditioning and orthostatic hypotension

The microgravity environment of spaceflight produces rapid cardiovascular changes which are adaptive and appropriate in that setting, but are associated with significant deconditioning and orthostatic hypotension on return to Earth's gravity. The rapidity with which these space flight induced changes appear and disappear provides an ideal model for studying the underlying pathophysiological mechanisms of deconditioning and orthostatic hypotension, regardless of etiology. Since significant deconditioning is seen after flights of very short duration, muscle atrophy due to inactivity plays, at most, a small role. These changes in circulatory control associated with cephalad fluid shifts, rather than inactivity per se, are probably more important factors. In order to test this hypothesis in a systematic way, a multidisciplinary approach which defines and integrates inputs and responses from a wide variety of circulatory sub-systems is required. The cardiovascular experiments selected for Spacelab Life Sciences flights 1 and 2 provide such an approach. Both human and animal models will be utilized. Pre- and post-flight characterization of the payload crew includes determination of maximal exercise capacity (bicycle ergometry), orthostatic tolerance (lower body negative pressure), alpha and beta adrenergic sensitivity (isoproterenol and phenylephrine infusions), baroreflex sensitivity (ECG-gated, stepwise changes in carotid artery transmural pressure with a pneumatic neck collar), and responses to a 24 h period of 5 deg head-down tilt. Measurements of cardiac output (CO2 and C2H2 rebreathing), cardiac chamber dimensions (phased-array 2-dimensional echocardiography), direct central venous pressure, leg volume (Thornton sock), limb blood flow and venous compliance (occlusion plethysmography), blood and plasma volumes, renal plasma flow and glomerular filtration rates, and various hormonal levels including catecholamines and atrial natriuretic factor will also be obtained. The central venous catheter will be inserted immediately pre-launch and monitored with heart rate and blood pressure in-flight until cardiac output, respiratory gas exchange and quantitative 2D echocardiography measurements can be performed. In-flight hemodynamic measurements will be repeated at rest and during submaximal exercise daily and also during maximal exercise midway through the flight to document the timecourse and extent of cardiovascular changes in the payload crew. Parallel studies are planned for the animals. In addition to measurements of right atrial and aortic pressures and cardiac output, a dorsal micro-circulatory chamber will allow determinations of changes in capillary and venular architecture and function in six of the rats. The techniques and findings from many of the SLS-1 and 2 supporting studies have already yielded significant information about circulatory regulation in patients with both hypo- and hypertension. The flight experiments themselves will provide new data to test the validity of both animal and human models currently used for simulating the fluid shifts of a micro-gravity environment. The development of effective countermeasures, not only for short and long duration space travellers, but also for Earth-bound medical patients can then be physiologically based on experimental data rather than anecdote.

Non-NASA Center↗
NASA NTRS1994

Effects of vibration on inertial wind-tunnel model attitude measurement devices

Results of an experimental study of a wind tunnel model inertial angle-of-attack sensor response to a simulated dynamic environment are presented. The inertial device cannot distinguish between the gravity vector and the centrifugal accelerations associated with wind tunnel model vibration, this situation results in a model attitude measurement bias error. Significant bias error in model attitude measurement was found for the model system tested. The model attitude bias error was found to be vibration mode and amplitude dependent. A first order correction model was developed and used for estimating attitude measurement bias error due to dynamic motion. A method for correcting the output of the model attitude inertial sensor in the presence of model dynamics during on-line wind tunnel operation is proposed.

Young, Clarence P., Jr.↗
NASA NTRS1991

Analysis of altimetry over the Aral Sea

Satellite based altimetric data taken by GEOS-3, SEASAT, and GEOSAT over the Aral Sea are analyzed and a least squares collocation technique is used to predict the geoid undulations on a 0.25 by 0.25 degree grid and to transform these geoid undulations to free air gravity anomalies. Rapp's 180 by 180 geopotential model is taken as the empirical model. The collocation procedure is performed with a set of local residual empirical covariance functions. For comparison, Rapp's global covariance functions and Jordan's self-consistent theoretical covariance functions based on Jordan's formulation and on locally derived parameters are also used to grid geoid undulations and to predict gravity anomalies. The sensitivity of the collocation results to the choice of covariance functions is discussed.

Au, Andrew Y.↗
NASA NTRS2015

A Numerical and Experimental Study of Coflow Laminar Diffusion Flames: Effects of Gravity and Inlet Velocity

In this work, the influence of gravity, fuel dilution, and inlet velocity on the structure, stabilization, and sooting behavior of laminar coflow methane-air diffusion flames was investigated both computationally and experimentally. A series of flames measured in the Structure and Liftoff in Combustion Experiment (SLICE) was assessed numerically under microgravity and normal gravity conditions with the fuel stream CH4 mole fraction ranging from 0.4 to 1.0. Computationally, the MC-Smooth vorticity-velocity formulation of the governing equations was employed to describe the reactive gaseous mixture; the soot evolution process was considered as a classical aerosol dynamics problem and was represented by the sectional aerosol equations. Since each flame is axisymmetric, a two-dimensional computational domain was employed, where the grid on the axisymmetric domain was a nonuniform tensor product mesh. The governing equations and boundary conditions were discretized on the mesh by a nine-point finite difference stencil, with the convective terms approximated by a monotonic upwind scheme and all other derivatives approximated by centered differences. The resulting set of fully coupled, strongly nonlinear equations was solved simultaneously using a damped, modified Newton's method and a nested Bi-CGSTAB linear algebra solver. Experimentally, the flame shape, size, lift-off height, and soot temperature were determined by flame emission images recorded by a digital camera, and the soot volume fraction was quantified through an absolute light calibration using a thermocouple. For a broad spectrum of flames in microgravity and normal gravity, the computed and measured flame quantities (e.g., temperature profile, flame shape, lift-off height, and soot volume fraction) were first compared to assess the accuracy of the numerical model. After its validity was established, the influence of gravity, fuel dilution, and inlet velocity on the structure, stabilization, and sooting tendency of laminar coflow methane-air diffusion flames was explored further by examining quantities derived from the computational results.

microgravity↗
NASA NTRS1979

Global accuracy estimates of point and mean undulation differences obtained from gravity disturbances, gravity anomalies and potential coefficients

Through the method of truncation functions, the oceanic geoid undulation is divided into two constituents: an inner zone contribution expressed as an integral of surface gravity disturbances over a spherical cap; and an outer zone contribution derived from a finite set of potential harmonic coefficients. Global, average error estimates are formulated for undulation differences, thereby providing accuracies for a relative geoid. The error analysis focuses on the outer zone contribution for which the potential coefficient errors are modeled. The method of computing undulations based on gravity disturbance data for the inner zone is compared to the similar, conventional method which presupposes gravity anomaly data within this zone.

Jekeli, C.↗
NASA NTRS1974

Global detailed geoid computation and model analysis

Comparisons and analyses were carried out through the use of detailed gravimetric geoids which we have computed by combining models with a set of 26,000 1 deg x 1 deg mean free air gravity anomalies. The accuracy of the detailed gravimetric geoid computed using the most recent Goddard earth model (GEM-6) in conjunction with the set of 1 deg x 1 deg mean free air gravity anomalies is assessed at + or - 2 meters on the continents of North America, Europe, and Australia, 2 to 5 meters in the Northeast Pacific and North Atlantic areas, and 5 to 10 meters in other areas where surface gravity data are sparse. The R.M.S. differences between this detailed geoid and the detailed geoids computed using the other satellite gravity fields in conjuction with same set of surface data range from 3 to 7 meters.

Marsh, J. G.↗
NASA NTRS1986

Investigation of the mode of compensation of Venus topography

The Venus gravity data derived from the Pioneer Venus Orbiter indicates a strong correlation of gravity to topography at all resolvable wavelengths. Focus was on an analysis in the spatial domain, using a geophysical model of topographic compensation together with the topography data to compute gravity vectors corresponding to the observed data and comparison of the calculated and observed gravity vectors.

Morgan, Paul↗
NASA NTRS1987

The effect of a gravity wave drag parameterization scheme on GLA fourth order GCM forecasts

Ten-day forecast experiments have been performed to determined whether the introduction of a simple orographic gravity wave drag scheme into a fourth-order GCM would reduce the climate drift of the fine resolution model and improve the model's medium range predictive skill. Error reduction due to the gravity waves is found in stratospheric predictions, where the improvement is confined mainly to the zonal mean component. Improvements are noted in the Northern Hemisphere climatology, where low level westerlies are weakened and shifted poleward, and in the Southern Hemisphere, where the roaring forties and fifties are better simulated.

Helfand, H. M.↗
NASA NTRS1993

The NASA/GISS Mars general circulation model: Preliminary experiments

The NASA/GISS Mars General Circulation Model (GCM) is an adapted version of the GISS Global Climate/Middle Atmosphere Model, specifically developed for the diagnostic validation and objective analysis of measured atmospheric temperatures from the Mars Observer Pressure Modulator Infrared Radiometer (PMIRR) experiment. The GISS Mars GCM has 23 vertical layers extending from the surface to approximately 80 km altitude, representing a vertical resolution of about 0.3 scale heights. The primitive (vertically hydrostatic) equations are solved in finite difference form on the Krakawa B grid, with a horizontal resolution of 8 deg x 10 deg (latitude-longitude). The model includes a diurnal solar cycle, heat transport within a two-layer ground, and a high-order 'slopes-scheme' for the advection of heat in the upper atmosphere. The radiative transfer scheme is based on the correlated k distribution method for the treatment of nongray gaseous absorption thermal emission, and multiple scattering, including options for suspended dust. A special feature of the model of particular importance for Mars is a parameterization of gravity-wave-induced drag incorporating orographic forcing, wind shear, convection, and radiative damping. The implementation of the GISS Mars model includes global maps of topography, roughness, and albedo.

Allison, Michael↗
NASA NTRS2022

Constraining Venus and Mars Internal Structures from the Gravity Response to Atmospheric Loading

The gravity fields of celestial bodies that possess an atmosphere are periodically perturbed by the redistribution of fluid mass associated with the atmospheric dynamics. A component of this perturbation is due to the gravitational response of the body to the deformation of its surface induced by the atmospheric pressure loading. The magnitude of this effect depends on the relation between the loading and the response in terms of geopotential variations measured by the load Love numbers. In this work, we simulate and analyze the gravity field generated by the atmospheres of Venus and Mars by accounting for different models of their internal structure. By precisely characterizing the phenomena that drive the mass transportation in the atmosphere through general circulation models, we determine the effect of the interior structure on the response to the atmospheric loading. An accurate estimation of the time-varying gravity field, which measures the atmospheric contribution, may provide significant constraints on the interior structure through the measurement of the load Love numbers. A combined determination of tidal and load Love numbers would enhance our knowledge of the interior of planetary bodies, providing further geophysical constraints in the inversion of internal structure models.The gravity fields of celestial bodies that possess an atmosphere are periodically perturbed by the redistribution of fluid mass associated with the atmospheric dynamics. A component of this perturbation is due to the gravitational response of the body to the deformation of its surface induced by the atmospheric pressure loading. The magnitude of this effect depends on the relation between the loading and the response in terms of geopotential variations measured by the load Love numbers. In this work, we simulate and analyze the gravity field generated by the atmospheres of Venus and Mars by accounting for different models of their internal structure. By precisely characterizing the phenomena that drive the mass transportation in the atmosphere through general circulation models, we determine the effect of the interior structure on the response to the atmospheric loading. An accurate estimation of the time-varying gravity field, which measures the atmospheric contribution, may provide significant constraints on the interior structure through the measurement of the load Love numbers. A combined determination of tidal and load Love numbers would enhance our knowledge of the interior of planetary bodies, providing further geophysical constraints in the inversion of internal structure models.

Mars↗
NASA NTRS2019

Long-Term, Non-Anthropogenic Groundwater Storage Changes Simulated by Three Global-Scale Hydrological Models

This study examined long-term, natural (i.e., excluding anthropogenic impacts) variability of groundwater storage worldwide. Groundwater storage changes were estimated by forcing three global-scale hydrological models with three 50+ year meteorological datasets. Evaluation using in situ groundwater observations from the U.S. and terrestrial water storage derived from the Gravity Recovery and Climate Experiment (GRACE) satellites showed that these models reasonably represented inter-annual variability of water storage, as indicated by correlations greater than 0.5 in most regions. Empirical orthogonal function analysis revealed influences of the El Niño Southern Oscillation (ENSO) on global groundwater storage. Simulated groundwater storage, including its global average, exhibited trends generally consistent with that of precipitation. Global total (natural) groundwater storage decreased over the past 5-7 decades with modeled rates ranging from 0.01 to 2.18 mm year-1. This large range can be attributed in part to groundwater’s low frequency (inter-decadal) variability, which complicates identification of real long-term trends even within a 50+ year time series. Results indicate that non-anthropogenic variability in groundwater storage is substantial, making knowledge of it fundamental to quantifying direct human impacts on groundwater storage.

Groundwater storage↗
NASA NTRS2019

Long-Term, Non-Anthropogenic Groundwater Storage Changes Simulated by Three Global-Scale Hydrological Models

This study examined long-term, natural (i.e., excluding anthropogenic impacts) variability of groundwater storage worldwide. Groundwater storage changes were estimated by forcing three global-scale hydrological models with three 50+ year meteorological datasets. evaluation using in situ groundwater observations from the U.S. and terrestrial water storage derived from the Gravity Recovery and Climate experiment (GRACe) satellites showed that these models reasonably represented inter-annual variability of water storage, as indicated by correlations greater than 0.5 in most regions. Empirical orthogonal function analysis revealed influences of the El Niño Southern Oscillation (ENSO) on global groundwater storage. simulated groundwater storage, including its global average, exhibited trends generally consistent with that of precipitation. Global total (natural) groundwater storage decreased over the past 5–7 decades with modeled rates ranging from 0.01 to 2.18 mm year−1. this large range can be attributed in part to groundwater’s low frequency (inter-decadal) variability, which complicates identification of real long-term trends even within a 50+ year time series. Results indicate that non-anthropogenic variability in groundwater storage is substantial, making knowledge of it fundamental to quantifying direct human impacts on groundwater storage.

Bailing Li↗
NASA NTRS1974

Wicking of liquids in screens

An investigation was conducted to determine the magnitude of the wicking rates of liquids in various screens. Evaluation of the parameters characterizing the wicking process resulted in the development of an expression which defined the wicking velocity in terms of screen and system geometry, liquid properties, and gravitational effects. Experiment data obtained both in normal gravity and in weightlessness demonstrated that the model successfully predicted the functional relation of the liquid properties and the distance from the liquid source to the wicking velocity. Because the pore geometry in the screens was complex, several screen geometric parameters were lumped into a single constant which was determined experimentally for each screen.

Symons, E. P.↗
NASA NTRS1976

Gravity effects on flame spreading over solid surfaces

The effects of gravity on the spreading of a flame over a solid combustible surface were determined. Flame propagation rates were measured from specimens of thin cellulose acetate sheets burning in both normal gravity (1 g) and reduced gravity (0 g) environments; the specimens were burned in various quiescent mixtures of oxygen, helium, argon, and nitrogen. A correlation for normal gravity and reduced gravity burning was obtained based on theoretical models of previous investigators.

Andracchio, C. R.↗