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At least 1,279 records · Page 71

Information-incorporated gene network construction with FDR control

Abstract Motivation Large-scale gene expression studies allow gene network construction to uncover associations among genes. To study direct associations among genes, partial correlation-based networks are preferred over marginal correlations. However, FDR control for partial correlation-based network construction is not well-studied. In addition, currently available partial correlation-based methods cannot take existing biological knowledge to help network construction while controlling FDR. Results In this paper, we propose a method called Partial Correlation Graph with Information Incorporation (PCGII). PCGII estimates partial correlations between each pair of genes by regularized node-wise regression that can incorporate prior knowledge while controlling the effects of all other genes. It handles high-dimensional data where the number of genes can be much larger than the sample size and controls FDR at the same time. We compare PCGII with several existing approaches through extensive simulation studies and demonstrate that PCGII has better FDR control and higher power. We apply PCGII to a plant gene expression dataset where it recovers confirmed regulatory relationships and a hub node, as well as several direct associations that shed light on potential functional relationships in the system. We also introduce a method to supplement observed data with a pseudogene to apply PCGII when no prior information is available, which also allows checking FDR control and power for real data analysis. Availability and implementation R package is freely available for download at https://cran.r-project.org/package=PCGII.

59 BASIC BIOLOGICAL SCIENCES↗

Adaptive Control for Load-Following of Boiling Water Reactors Part I: Linear Systems and Fully-Observable Dynamics

Automation control is a key strategy to improve the economic competitiveness of nuclear power plants. Not only does it help reduce operational costs, but it also extends the value proposition of these plants to nontraditional markets, including unattended operations in remote villages and space. However, the dynamics of the operating environments of nuclear reactors are subject to changes over time, and there are no widely adopted methods to ensure that the automation strategy will remain effective over the extended durations required for these applications. Adaptive control is a discipline that offers the possibility to accommodate such changes online. However, it relies on mathematical assumptions that must be respected to ensure robustness and reliability. In this work, we derive an adaptive control formulation for linear systems in which all states are observable and apply it to an instance of load-follow operation for Boiling Water Reactors. We assumed uncertainty in two factors: the temperature coefficient and the control rod worth, both of which are affected over time by the evolution of the nuclear reactor core environment. With an arbitrary penalty factor of 5, we found that the mean absolute and integral time absolute errors can be reduced by more than 90%, underscoring the strength of adaptive control. To extend the application to more challenges, different uncertainties and load-follow trajectories, as well as new formulations that include non-linearity and partial observability, are currently being developed.

22 - GENERAL STUDIES OF NUCLEAR REACTORS↗

Refractory-based thermal energy storage for industrial process heat: one-dimensional modeling, control, and optimization

The variable and weather-dependent output of wind and solar power plants present a substantial challenge for planning and operating electricity-systems, particularly in the absence of cost-effective and dispatchable energy storage technologies. This study investigates a high-temperature, electrically heated, refractory-based thermal energy storage (RTES) system that stores electrical energy as sensible heat in dense ceramic bricks over the 950–1800 °C range. The stored heat can be discharged as a controlled hot-gas stream for industrial heating, fuel substitution in high-temperature processes, or electricity generation. The main novelty is a comprehensive modelling, control, mapping, and optimization framework that integrates one-dimensional transient gas–solid heat transfer, fan-assisted discharge, bypass-flow regulation, reheating logic, fan-power evaluation, insulation-loss assessment, and genetic-algorithm-based design optimization. The model uses feedback from outlet temperature and delivered power to regulate discharge, while a two-stage genetic algorithm optimizes brick-channel geometry, gas-flow operation, and multilayer insulation thicknesses. Storage capacities below 50 MWh and discharge powers of 5–30 MW are analyzed to evaluate hold time, thermal delivery, fan-power penalty, heat loss, state-of-charge evolution, and indicative capital cost. Results demonstrate that optimized and well-insulated refractory-based thermal energy storage units can provide stable, efficient, and repeatable heat delivery over multiple discharge cycles. The generated performance and cost maps support modular refractory thermal energy storage as a practical option for large-scale integration of wind and solar generation and for high-temperature industrial process heat.

25 ENERGY STORAGE↗

NREL's Advanced Distribution Management System (ADMS) Test Bed

NREL's advanced distribution management system (ADMS) test bed is a vendor-neutral resource for evaluating existing and future ADMS functionalities in a realistic laboratory setting. The test bed uses Opal-RT's ePHASORsim and eMEGAsim products interfaced with an OpenDSS power system simulation through the HELICS cosimulation platform developed by multiple DOE laboratories; and with power and controller hardware. NREL will present an overview of the test bed and the technologies included within it, and also some examples of how the test bed has been used to address industry challenges.

24 POWER TRANSMISSION AND DISTRIBUTION↗

Mitigating the Effect of Wind Gusts on Local Run-of-River Hydropower Plants Using Cooperative Control

This paper focuses on the challenges and solutions associated with the integration of wind farms in a hydro- dominated power system. Due to sudden increases in wind power, the system frequency can increase, causing excessive reduction in the run-of-river (ROR) system’s power. Considering their small pondage, this can result in damage to the physical structure due to water level violations which are also penalized by stakeholders. To prevent excessive ROR power deviations, ROR governor wear and tear, and to prevent tie-line deviations, a centralized, distributed, and hybrid scheme for coordinating the response from a cluster of ROR plants is examined. Both centralized and distributed control as well as their hybrids can reduce frequency peaks. However, the inclusion of decentralized cooperative controls leads to reduced governor actions from fast- acting plants while enhancing net response from the hydro unit cluster.

13 HYDRO ENERGY↗

Designer membraneless organelles sequester native factors for control of cell behavior

Subcellular compartmentalization of macromolecules increases flux and prevents inhibitory interactions to control biochemical reactions. Inspired by this functionality, we sought to build designer compartments that function as hubs to regulate the flow of information through cellular control systems. Here we report a synthetic membraneless organelle platform to control endogenous cellular activities through sequestration and insulation of native proteins. We engineer and express a disordered protein scaffold to assemble micron size condensates and recruit endogenous clients via genomic tagging with high-affinity dimerization motifs. By relocalizing up to ninety percent of a targeted enzymes to synthetic condensates, we efficiently control cellular behaviors, including proliferation, division, and cytoskeletal organization. Further, we demonstrate multiple strategies for controlled cargo release from condensates to switch cells between functional states. These synthetic organelles offer a powerful and generalizable approach to modularly control cell decision-making in a variety of model systems with broad applications for cellular engineering.

37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CH↗

Employing a Hardware-in-the-Loop Approach to Realize a Fully Homomorphic Controller for a Small Modular Advanced High Temperature Reactor

This paper addresses the cybersecurity challenges of advanced nuclear reactors by integrating fully homomorphic encryption (FHE) into their control systems, enabling encrypted processing of control signals without compromising functionality. Advanced nuclear reactors, including Small Modular Reactors (SMRs) and microreactors, aim to achieve autonomous and remote operations, reducing costs and enhancing competitiveness. However, these advancements expand the attack surface for cyberattacks, particularly in autonomous and remote operation scenarios. Cyberattacks can exploit vulnerabilities to manipulate physical processes, causing shutdowns, asset damage, or public harm. Such attacks begin with passive reconnaissance, where adversaries intercept communications or observe behaviors to gather information, which is then leveraged to execute cyber-physical attacks by injecting malicious commands. Nuclear power must adopt cybersecurity protection measures to secure the integrity and availability of their digital control systems. This paper demonstrates the application of FHE to secure operations by enabling encrypted processing of sensitive signals and parameters -- ensuring privacy without exposing data. FHE supports secure mathematical operations on encrypted data without requiring decryption. Using a hardware-in-the-loop (HIL) approach, this paper implements an FHE-integrated controller on a BeagleBone Black (BBB) controlling a simulation of the Small Modular Advanced High Temperature Reactor (SmAHTR). By doing so, the encrypted controller protects the integrity of critical set points and control signals during transmission and processing. Thus, FHE-integrated controllers enhance secure operations of advanced nuclear reactors while maintaining functionality.

control systems↗

Data-driven quantum approximate optimization algorithm for power systems

Abstract Quantum technology provides a ground-breaking methodology to tackle challenging computational issues in power systems. It is especially promising for Distributed Energy Resources (DERs) dominant systems that have been widely developed to promote energy sustainability. In those systems, knowing the maximum sections of power and data delivery is essential for monitoring, operation, and control. However, high computational effort is required. By leveraging quantum resources, Quantum Approximate Optimization Algorithm (QAOA) provides a means to search for these sections efficiently. However, QAOA performance relies heavily on critical parameters, especially for weighted graphs. Here we present a data-driven QAOA, which transfers quasi-optimal parameters between weighted graphs based on the normalized graph density. We verify the strategy with 39,774 expectation value calculations. Without parameter optimization, our data-driven QAOA is comparable with the Goemans-Williamson algorithm. This work advances QAOA and pilots its practical application to power systems in noisy intermediate-scale quantum devices.

Jing, Hang (ORCID:0000000256343489)↗

Improving EV Charging Resilience under a Device Fault Condition

This paper presents a multi-layer control framework that can improve resilience of an electric vehicle (EV) charging system when a device fault occurs in an EV charger power converter. The multi-layer framework built in a hierarchical structure allows fast protection and device fault ride through (DFRT), active status monitoring, and control optimization to improve the charging resilience. The feasibility and the effectiveness of the DFRT response and the control optimization are verified through controller hardware-in-the-loop demonstration.

Kim, Namwon↗

Enabling Evaluation of a Southern Company Distribution Feeder on NREL ADMS Test Bed: Cooperative Research and Development (Final Report)

The objective of this project is to enable evaluation of a Southern Company distribution feeder on the Advanced Distribution Management System (ADMS) test bed. The long-term goal is to evaluate a federated distributed energy resource (DER) management solution that aggregates DERs through either direct control, transactive control or an aggregator to provide bulk services while observing distribution system voltage and power constraints. The DER aggregation needs to be coordinated with an ADMS that is responsible for reliable power delivery across the distribution systems. This project takes the first step towards enabling such evaluation by deploying an ADMS from Oracle (Southern Company's ADMS supplier) with a Southern Company feeder at NREL.

24 POWER TRANSMISSION AND DISTRIBUTION↗

A novel large-scale EV charging scheduling algorithm considering V2G and reactive power management based on ADMM

Electric vehicle aggregators (EVAs) that utilize vehicle-to-grid (V2G) technologies can function as both controllable loads and virtual power plants, providing key energy management services to the distribution system operator (DSO). EVAs can also balance the grid’s reactive power as a virtual static VAR compensator (SVC) and provide voltage stability by utilizing advanced electric vehicle (EV) chargers that are capable of four-quadrant operations to provide reactive power management. Finally, managed charging can benefit EVAs themselves by minimizing power factor penalties in their electricity bills. In this paper, we propose a novel EV charging scheduling algorithm based on a hierarchical distributed optimization framework that minimizes peak load and provides reactive power compensation for the DSO by collaboration with EVAs that manage both the active and the reactive charging and discharging power of participating EVs. Utilizing the alternative direction method of multipliers (ADMM), the proposed distributed optimization approach scales well with increased EV charging infrastructure by balancing active and reactive power while decreasing computational burden. In our proposed hierarchical approach, each EVA schedules the active and reactive EV charging and discharging power for 1) reactive power compensation in order to minimize power factor penalty and electricity cost accrued by the EVA, 2) satisfaction of each EV’s energy demand at minimal charging cost, and 3) peak shaving and load management for the DSO. When compared with an uncoordinated charging model, the efficacy of this proposed model is successfully demonstrated through a 300% decreased peak EV load for the DSO, 28% lower electricity costs for EV users, and 98.55% smaller power factor penalty, along with 17.58% lower overall electricity costs, for EVAs. The performance of our approach is validated in a case study with 50 EVs at multiple EVAs in an IEEE 13-bus test case and compared the results with uncoordinated EV charging.

24 POWER TRANSMISSION AND DISTRIBUTION↗

Fabrication of neutron absorbing metal hydride entrained ceramic matrix shield composites

With significant improvement in High Temperature Superconductors (HTS), several projects are adopting HTS technology for fusion power systems. Compact HTS tokamaks offer potential advantages including lower plant costs, enhanced plasma control, and ultimately lower cost of electricity. However, as compact reactors have a reduced radial build to accommodate shielding, HTS degradation due to radiation damage or heating is a significant and potentially design limiting issue. Shielding must mitigate threats to the superconducting coils: neutron cascade damage, heat deposition and potentially organic insulator damage due x-rays. Unfortunately, there are currently no hi-performance shielding materials to enable the potential performance enhancement offered by HTS. In this work, we present a manufacturing method to fabricate a new class of composite shields that are high performance, high operating temperature, and simultaneously neutron absorbing and neutron moderating. The composite design consists of an entrained metal-hydride phase within a radiation stable MgO ceramic host matrix. We discuss the fabrication, characterization, and thermophysical performance data for a series of down-selected composite materials inspired by future fusion core designs and their operational performance metrics. To our knowledge these materials represent the first ceramic composite shield materials containing significant metal hydrides.

70 PLASMA PHYSICS AND FUSION TECHNOLOGY↗

Validation of Maui PSCAD Model: Motivation, Methodology, and Lessons Learned: Preprint

As power systems become increasingly dependent on inverter-based resources, the dominant physical and control interactions that determine system stability may no longer be accurately captured in positive sequence dynamic simulation tools; electromagnetic transient (EMT) simulations may be needed. This paper describes the process of creating and validating an EMT model of the entire Maui island transmission system in PSCAD software. The model is validated against the utility's PSSE model and against field data for an event that consisted of a single-phase fault followed by a generation trip. The methodology and lessons learned are summarized here.

41 EE - Solar Energy Technologies Office (EE-4S)↗

Probing Signal-Based Inertia and Frequency Response Estimation for Power Systems With High Levels of Inverter-Based Resources

Power system inertia is the inherent capability of a power system to resist changes in its frequency during disturbances. Real-time inertia estimation technology has become more important due to the low-inertia issues caused by the increasing integration levels of inverter-based resources (IBRs) from renewable energy; however, existing inertia estimation methods hardly consider multiple frequency response controls that act within the same time frame as conventional inertial response, thus making measured inertia values vary under different testing conditions. To resolve this issue, this paper proposes a novel real-time estimation method to simultaneously estimate a power system's inertia constant and frequency response droop constant using a well-designed probing signal. First, we formulate the inertia and frequency response model of a power system with IBRs. Second, through the integration and manipulation of the developed model, we propose a multivariate linear regression-based estimation method that is resilient to measurement noise. Third, we design a probing signal that can be injected by IBRs to incite the required transients for estimation. Finally, we validate the proposed estimation method through comprehensive power-hardware-in-the-loop experiments using inverter hardware and a realistic island power system model. The results demonstrate that the proposed method can accurately estimate the inertia and droop value of the power system with grid-following IBRs and grid-forming IBRs with virtual synchronous machine control.

frequency response↗

Probing Signal-Based Inertia and Frequency Response Estimation for Power Systems with High Penetration of Inverter-Based Resources: Preprint

Power system inertia is the inherent capability of a power system to resist changes in its frequency during disturbances. Real-time inertia estimation technology has become more important due to the low-inertia issues caused by the increasing integration levels of inverter-based resources (IBRs) from renewable energy; however, existing inertia estimation methods hardly consider multiple frequency response controls that act within the same time frame as conventional inertial response, thus making measured inertia values vary under different testing conditions. To resolve this issue, this paper proposes a novel real-time estimation method to simultaneously estimate a power system's inertia constant and frequency response droop constant using a well-designed probing signal. First, we formulate the inertia and frequency response model of a power system with IBRs. Second, through the integration and manipulation of the developed model, we propose a multivariate linear regression- based estimation method that is resilient to measurement noise. Third, we design a probing signal that can be injected by IBRs to incite the required transients for estimation. Finally, we validate the proposed estimation method through comprehensive power- hardware-in-the-loop experiments using inverter hardware and a realistic island power system model. The results demonstrate that the proposed method can accurately estimate the inertia and droop value of the power system with grid-following IBRs and grid-forming IBRs with virtual synchronous machine control.

frequency response↗

Performance Evaluation of an Advanced Distributed Energy Resource Management Algorithm

This paper presents performance evaluation of a new distributed energy resource management system (DERMS) algorithm via an advanced hardware-in-the-loop (HIL) platform. The HIL platform provides realistic testing in a laboratory environment, including the accurate modeling of sub-transmission and distribution networks, the DERMS software controller, and 84 power hardware solar photovoltaic (PV) inverters, standard communication protocols, and a capacitor bank controller. The DERMS algorithm is also called, Grid-Optimization of Solar (GO-Solar) platform which includes predictive state estimation (PSE) and online multiple objective optimization (OMOO) to dispatch the legacy devices and distributed energy resources (e.g., PV). The voltage regulation performance is evaluated under three scenarios, volt-var smart inverter (baseline), and DERMS control for 100% and 30% of PV. The results show that controlling 30% of PV systems with the GO-Solar platform may provide the best balance of control performance and implementation cost.

distributed energy resource management system (DER↗