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Assessing Crew Medical Officer Preparedness for International Space Station Missions

INTRODUCTION Astronaut crew medical officers (CMO) undergo additional, specialized training to provide medical support onboard the International Space Station (ISS). CMO training focuses on utilizing resources on-station and optimizing communication with ground-based expertise to manage both common minor conditions as well as emergency/trauma situations. As NASA moves towards future Artemis and exploration class missions, we sought CMO perspectives on past, present, and future CMO training and medical resourcing to help inform mission planners regarding medical risk mitigation considerations. We present an interview-based qualitative assessment of CMO preparedness for the International Space Station with the aim to help iterate future training flows for Low Earth Orbit, Artemis, and exploration-class missions. METHODS A semi-structured interview tool was developed to assess CMO experience and their recommendations for future mission training considerations. Participants were recruited from former or current US astronauts who were designated as CMO and subsequently flew to the International Space Station. 10 former CMOs took part in the study. Interview transcripts were deidentified and evaluated for qualitative thematic analysis by two independent coders with NVivo Software suite (Lumivero, Denver, CO), and emergent themes were compiled. RESULTS Former CMO crew expressed appropriate preparedness for current ISS medical capabilities and requirements. They identified the role of the CMO as serving as a healthcare extender to ground-based flight surgeons for ISS and other LEO missions. Individuals with prior medical experience were preferred though not felt to be necessary for LEO missions. For exploration class missions with limitations in ground communication, a physician-as-CMO and more rigorous training curricula for both the CMO and astronaut crew were desired. DISCUSSION Former NASA astronaut crew were interviewed to retrospectively assess their preparedness as ISS crew medical officers and hypothesize future medical knowledge, skill, and ability needs. Along with medical operations subject matter expert opinion and advanced probabilistic risk assessment modeling, past CMO experience can help inform future CMO training considerations and responsibilities for future Artemis and exploration class missions.

M A Labarbera↗
NASA NTRS1988

Reliable use of determinants to solve nonlinear structural eigenvalue problems efficiently

The analytical derivation, numerical implementation, and performance of a multiple-determinant parabolic interpolation method (MDPIM) for use in solving transcendental eigenvalue (critical buckling or undamped free vibration) problems in structural mechanics are presented. The overall bounding, eigenvalue-separation, qualified parabolic interpolation, accuracy-confirmation, and convergence-recovery stages of the MDPIM are described in detail, and the numbers of iterations required to solve sample plane-frame problems using the MDPIM are compared with those for a conventional bisection method and for the Newtonian method of Simpson (1984) in extensive tables. The MDPIM is shown to use 31 percent less computation time than bisection when accuracy of 0.0001 is required, but 62 percent less when accuracy of 10 to the -8th is required; the time savings over the Newtonian method are about 10 percent.

Williams, F. W.↗
NASA NTRS1993

A multilevel adaptive projection method for unsteady incompressible flow

There are two main requirements for practical simulation of unsteady flow at high Reynolds number: the algorithm must accurately propagate discontinuous flow fields without excessive artificial viscosity, and it must have some adaptive capability to concentrate computational effort where it is most needed. We satisfy the first of these requirements with a second-order Godunov method similar to those used for high-speed flows with shocks, and the second with a grid-based refinement scheme which avoids some of the drawbacks associated with unstructured meshes. These two features of our algorithm place certain constraints on the projection method used to enforce incompressibility. Velocities are cell-based, leading to a Laplacian stencil for the projection which decouples adjacent grid points. We discuss features of the multigrid and multilevel iteration schemes required for solution of the resulting decoupled problem. Variable-density flows require use of a modified projection operator--we have found a multigrid method for this modified projection that successfully handles density jumps of thousands to one. Numerical results are shown for the 2D adaptive and 3D variable-density algorithms.

Howell, Louis H.↗
NASA NTRS1951

Analysis of plane-plastic stress problems with axial symmetry in strain-hardening range

A simple method is developed for solving plane-plastic-stress problems with axial symmetry in the strain-hardening range which is based on the deformation theory of plasticity employing the finite-strain concept. The equations defining the problems are first reduced to two simultaneous nonlinear differential equations involving two dependent variables: (a) the octahedral shear strain, and (b) a parameter indicating the ratio of principal stresses. By multiplying the load and dividing the radius by an arbitrary constant, it is possible to solve these problems without iteration for any value of the modified load. The constant is determined by the boundary condition. This method is applied to a circular membrane under pressure, a rotating disk without and with a central hole, and an infinite plate with a circular hole. Two materials, inconel x and 16-25-6, the octahedral shear stress-strain relations of which do not follow the power law, are used. Distributions of octahedral shear strain, as well as of principal stresses and strains, are obtained. These results are compared with the results of the same problems in the elastic range.

Wu, M H Lee↗
NASA NTRS1996

Optimization of Residual Stresses in MMC's through Process Parameter Control and the use of Heterogeneous Compensating/Compliant Interfacial Layers. OPTCOMP2 User's Guide

A user's guide for the computer program OPTCOMP2 is presented in this report. This program provides a capability to optimize the fabrication or service-induced residual stresses in unidirectional metal matrix composites subjected to combined thermomechanical axisymmetric loading by altering the processing history, as well as through the microstructural design of interfacial fiber coatings. The user specifies the initial architecture of the composite and the load history, with the constituent materials being elastic, plastic, viscoplastic, or as defined by the 'user-defined' constitutive model, in addition to the objective function and constraints, through a user-friendly data input interface. The optimization procedure is based on an efficient solution methodology for the inelastic response of a fiber/interface layer(s)/matrix concentric cylinder model where the interface layers can be either homogeneous or heterogeneous. The response of heterogeneous layers is modeled using Aboudi's three-dimensional method of cells micromechanics model. The commercial optimization package DOT is used for the nonlinear optimization problem. The solution methodology for the arbitrarily layered cylinder is based on the local-global stiffness matrix formulation and Mendelson's iterative technique of successive elastic solutions developed for elastoplastic boundary-value problems. The optimization algorithm employed in DOT is based on the method of feasible directions.

Pindera, Marek-Jerzy↗
NASA NTRS1991

Evaluation of a transfinite element numerical solution method for nonlinear heat transfer problems

Laplace transform techniques have been widely used to solve linear, transient field problems. A transform-based algorithm enables calculation of the response at selected times of interest without the need for stepping in time as required by conventional time integration schemes. The elimination of time stepping can substantially reduce computer time when transform techniques are implemented in a numerical finite element program. The coupling of transform techniques with spatial discretization techniques such as the finite element method has resulted in what are known as transfinite element methods. Recently attempts have been made to extend the transfinite element method to solve nonlinear, transient field problems. This paper examines the theoretical basis and numerical implementation of one such algorithm, applied to nonlinear heat transfer problems. The problem is linearized and solved by requiring a numerical iteration at selected times of interest. While shown to be acceptable for weakly nonlinear problems, this algorithm is ineffective as a general nonlinear solution method.

Cerro, J. A.↗
NASA NTRS1984

Aerospace engineering design by systematic decomposition and multilevel optimization

A method for systematic analysis and optimization of large engineering systems, by decomposition of a large task into a set of smaller subtasks that is solved concurrently is described. The subtasks may be arranged in hierarchical levels. Analyses are carried out in each subtask using inputs received from other subtasks, and are followed by optimizations carried out from the bottom up. Each optimization at the lower levels is augmented by analysis of its sensitivity to the inputs received from other subtasks to account for the couplings among the subtasks in a formal manner. The analysis and optimization operations alternate iteratively until they converge to a system design whose performance is maximized with all constraints satisfied. The method, which is still under development, is tentatively validated by test cases in structural applications and an aircraft configuration optimization.

Sobieszczanski-Sobieski, J.↗
NASA NTRS1985

Multi-grid calculation of transonic potential flows

The finite-volume method discussed by Jameson and Caughey (1977), and Caughey and Jameson (1979, 1980) has made it possible to calculate the transonic potential flow past any configuration for which a suitable boundary-conforming coordinate grid can be constructed. However, computations for practical three-dimensional problems have remained quite expensive in terms of the required computer time. The reason for this is primarily related to the large number of grid cells necessary for adequate resolution in these complex three-dimensional problems, taking into account the large number of iterations required to achieve even modest convergence on these fine grids. The present chapter provides a description of work directed at removing this latter difficulty by making use of the multigrid method. Attention is given to finite-volume formulation, multigrid iteration, geometrical aspects, and computed results.

Caughey, D. A.↗
NASA NTRS2004

Uncertainty-Based Approach for Dynamic Aerodynamic Data Acquisition and Analysis

Development of improved modeling methods to provide increased fidelity of flight predictions for aircraft motions during flight in flow regimes with large nonlinearities requires improvements in test techniques for measuring and characterizing wind tunnel data. This paper presents a method for providing a measure of data integrity for static and forced oscillation test techniques. Data integrity is particularly important when attempting to accurately model and predict flight of today s high performance aircraft which are operating in expanded flight envelopes, often maneuvering at high angular rates at high angles-of-attack, even above maximum lift. Current aerodynamic models are inadequate in predicting flight characteristics in the expanded envelope, such as rapid aircraft departures and other unusual motions. Present wind tunnel test methods do not factor changes of flow physics into data acquisition schemes, so in many cases data are obtained over more iterations than required, or insufficient data may be obtained to determine a valid estimate with statistical significance. Additionally, forced oscillation test techniques, one of the primary tools used to develop dynamic models, do not currently provide estimates of the uncertainty of the results during an oscillation cycle. A method to optimize the required number of forced oscillation cycles based on decay of uncertainty gradients and balance tolerances is also presented.

Heim, Eugene H. D.↗
NASA NTRS1992

Fast methods to numerically integrate the Reynolds equation for gas fluid films

The alternating direction implicit (ADI) method is adopted, modified, and applied to the Reynolds equation for thin, gas fluid films. An efficient code is developed to predict both the steady-state and dynamic performance of an aerodynamic journal bearing. An alternative approach is shown for hybrid journal gas bearings by using Liebmann's iterative solution (LIS) for elliptic partial differential equations. The results are compared with known design criteria from experimental data. The developed methods show good accuracy and very short computer running time in comparison with methods based on an inverting of a matrix. The computer codes need a small amount of memory and can be run on either personal computers or on mainframe systems.

Dimofte, Florin↗
NASA NTRS1984

Aerospace engineering design by systematic decomposition and multilevel optimization

This paper describes a method for systematic analysis and optimization of large engineering systems, e.g., aircraft, by decomposition of a large task into a set of smaller, self-contained subtasks that can be solved concurrently. The subtasks may be arranged in many hierarchical levels with the assembled system at the top level. Analyses are carried out in each subtask using inputs received from other subtasks, and are followed by optimizations carried out from the bottom up. Each optimization at the lower levels is augmented by analysis of its sensitivity to the inputs received from other subtasks to account for the couplings among the subtasks in a formal manner. The analysis and optimization operations alternate iteratively until they converge to a system design whose performance is maximized with all constraints satisfied. The method, which is still under development, is tentatively validated by test cases in structural applications and an aircraft configuration optimization. It is pointed out that the method is intended to be compatible with the typical engineering organization and the modern technology of distributed computing.

Sobieszczanski-Sobieski, J.↗
NASA NTRS1985

An Algorithm for Efficient Maximum Likelihood Estimation and Confidence Interval Determination in Nonlinear Estimation Problems

An algorithm for maximum likelihood (ML) estimation is developed with an efficient method for approximating the sensitivities. The algorithm was developed for airplane parameter estimation problems but is well suited for most nonlinear, multivariable, dynamic systems. The ML algorithm relies on a new optimization method referred to as a modified Newton-Raphson with estimated sensitivities (MNRES). MNRES determines sensitivities by using slope information from local surface approximations of each output variable in parameter space. The fitted surface allows sensitivity information to be updated at each iteration with a significant reduction in computational effort. MNRES determines the sensitivities with less computational effort than using either a finite-difference method or integrating the analytically determined sensitivity equations. MNRES eliminates the need to derive sensitivity equations for each new model, thus eliminating algorithm reformulation with each new model and providing flexibility to use model equations in any format that is convenient. A random search technique for determining the confidence limits of ML parameter estimates is applied to nonlinear estimation problems for airplanes. The confidence intervals obtained by the search are compared with Cramer-Rao (CR) bounds at the same confidence level. It is observed that the degree of nonlinearity in the estimation problem is an important factor in the relationship between CR bounds and the error bounds determined by the search technique. The CR bounds were found to be close to the bounds determined by the search when the degree of nonlinearity was small. Beale's measure of nonlinearity is developed in this study for airplane identification problems; it is used to empirically correct confidence levels for the parameter confidence limits. The primary utility of the measure, however, was found to be in predicting the degree of agreement between Cramer-Rao bounds and search estimates.

Murphy, Patrick Charles↗
NASA NTRS1989

Conjugate gradient type methods for linear systems with complex symmetric coefficient matrices

We consider conjugate gradient type methods for the solution of large sparse linear system Ax equals b with complex symmetric coefficient matrices A equals A(T). Such linear systems arise in important applications, such as the numerical solution of the complex Helmholtz equation. Furthermore, most complex non-Hermitian linear systems which occur in practice are actually complex symmetric. We investigate conjugate gradient type iterations which are based on a variant of the nonsymmetric Lanczos algorithm for complex symmetric matrices. We propose a new approach with iterates defined by a quasi-minimal residual property. The resulting algorithm presents several advantages over the standard biconjugate gradient method. We also include some remarks on the obvious approach to general complex linear systems by solving equivalent real linear systems for the real and imaginary parts of x. Finally, numerical experiments for linear systems arising from the complex Helmholtz equation are reported.

Freund, Roland↗
NASA NTRS1988

A transonic interactive boundary-layer theory for laminar and turbulent flow over swept wings

A 3-D laminar and turbulent boundary-layer method is developed for compressible flow over swept wings. The governing equations and curvature terms are derived in detail for a nonorthogonal, curvilinear coordinate system. Reynolds shear-stress terms are modeled by the Cebeci-Smith eddy-viscosity formulation. The governing equations are descretized using the second-order accurate, predictor-corrector finite-difference technique of Matsuno, which has the advantage that the crossflow difference formulas are formed independent of the sign of the crossflow velocity component. The method is coupled with a full potential wing/body inviscid code (FLO-30) and the inviscid-viscous interaction is performed by updating the original wing surface with the viscous displacement surface calculated by the boundary-layer code. The number of these global iterations ranged from five to twelve depending on Mach number, sweep angle, and angle of attack. Several test cases are computed by this method and the results are compared with another inviscid-viscous interaction method (TAWFIVE) and with experimental data.

Woodson, Shawn H.↗
NASA NTRS1956

Extrapolation techniques applied to matrix methods in neutron diffusion problems

A general matrix method is developed for the solution of characteristic-value problems of the type arising in many physical applications. The scheme employed is essentially that of Gauss and Seidel with appropriate modifications needed to make it applicable to characteristic-value problems. An iterative procedure produces a sequence of estimates to the answer; and extrapolation techniques, based upon previous behavior of iterants, are utilized in speeding convergence. Theoretically sound limits are placed on the magnitude of the extrapolation that may be tolerated. This matrix method is applied to the problem of finding criticality and neutron fluxes in a nuclear reactor with control rods. The two-dimensional finite-difference approximation to the two-group neutron fluxes in a nuclear reactor with control rods. The two-dimensional finite-difference approximation to the two-group neutron-diffusion equations is treated. Results for this example are indicated.

Mccready, Robert R↗
NASA NTRS1991

A multi-point inverse airfoil design method based on conformal mapping

An exact method of multipoint inverse airfoil design for incompressible flow is presented. Multipoint design is handled by dividing the airfoil into a number of desired segments. For each segment the velocity distribution is prescribed together with an angle of attack at which the prescribed velocity distribution is to be achieved. In this manner, multipoint design objectives can be taken into account in the initial specification of the velocity distribution. In order for the multipoint inverse airfoil design problem to be well posed, three integral constraints and several conditions arise which must be satisfied. Further restrictions are imposed if the airfoil is to have a specified pitching moment, thickness ratio, or other constraints. The system of equations is solved partly as a linear system and partly through multidimensional Newton iteration. Since the velocity distribution is prescribed about the circle in the angular coordinate, specification of the velocity in terms of arc length is handled through the multidimensional Newton iteration as well. The current formulation sets the stage for a more general multipoint inverse airfoil design method in which it will be possible to specify the velocity distribution, some boundary-layer development, or the surface geometry along a segment.

Selig, Michael S.↗
NASA NTRS1970

Rapid method for interconversion of binary and decimal numbers

Decoding tree consisting of 40-bit semiconductor read-only memories interconverts binary and decimal numbers 50 to 100 times faster than current methods. Decimal-to-binary conversion algorithm is based on a divided-by-2 iterative equation, binary-to-decimal conversion algorithm utilizes multiplied-by-2 iterative equation.

Lim, R. S.↗
NASA NTRS1972

Optimal shield mass distribution for space radiation protection

Computational methods have been developed and successfully used for determining the optimum distribution of space radiation shielding on geometrically complex space vehicles. These methods have been incorporated in computer program SWORD for dose evaluation in complex geometry, and iteratively calculating the optimum distribution for (minimum) shield mass satisfying multiple acute and protected dose constraints associated with each of several body organs.

Billings, M. P.↗