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At least 1,279 records · Page 71

Intergalactic medium emission observations with the cosmic web imager. I. The circum-QSO medium of QSO 1549+19, and evidence for a filamentary gas inflow

The Palomar Cosmic Web Imager (PCWI), an integral field spectrograph designed to detect and map low surface brightness emission, has obtained imaging spectroscopic maps of Lyα from the circum-QSO medium (CQM) of QSO HS1549+19 at redshift z = 2.843. Extensive extended emission is detected from the CQM, consistent with fluorescent and pumped Lyα produced by the ionizing and Lyα continuum of the QSO. Many features present in PCWI spectral images match those detected in narrow-band images. Filamentary structures with narrow line profiles are detected in several cases as long as 250-400 kpc. One of these is centered at a velocity redshifted with respect to the systemic velocity, and displays a spatially collimated and kinematically cold line profile increasing in velocity width approaching the QSO. This suggests that the filament gas is infalling onto the QSO, perhaps in a cold accretion flow. Because of the strong ionizing flux, the neutral column density is low, typically N(H I)∼10{sup 12}--10{sup 15} cm{sup −2}, and the line center optical depth is also low (typically τ{sub 0} < 10), insufficient to display well separated double peak emission characteristic of higher line optical depths. With a simple ionization and cloud model we can very roughly estimate the total gas mass (log M {sub gas} = 12.5 ± 0.5) and the total (log M {sub tot} = 13.3 ± 0.5). We can also calculate a kinematic mass from the total line profile (2 × 10{sup 13} M {sub ☉}), which agrees with the mass estimated from the gas emission. The intensity-binned spectrum of the CQM shows a progression in kinematic properties consistent with heirarchical structure formation.

79 ASTRONOMY AND ASTROPHYSICS↗

Early Transcriptomic Changes in the Ileal Pouch Provide Insight into the Molecular Pathogenesis of Pouchitis and Ulcerative Colitis

Background: Ulcerative colitis (UC) only involves the colonic mucosa. Yet, nearly 50% of patients with UC who undergo total proctocolectomy with ileal pouch anal anastomosis develop UC-like inflammation of the ileal pouch (pouchitis). By contrast, patients with familial adenomatous polyposis (FAP) with ileal pouch anal anastomosis develop pouchitis far less frequently. We hypothesized that pathogenic events associated with the development of UC are recapitulated by colonic-metaplastic transcriptomic reprogramming of the UC pouch. Methods: We prospectively sampled pouch and prepouch ileum mucosal biopsies in patients with UC with ileal pouch anal anastomosis 4, 8, and 12 months after their pouch was in continuity. Mucosal samples were also obtained from patients with FAP. Transcriptional profiles of the UC and FAP pouch and prepouch ileum were investigated via RNA sequencing and compared with data from a previously published microarray study. Results: Unlike patients with FAP, subjects with UC exhibited a large set of differentially expressed genes between the pouch and prepouch ileum as early as 4 months after pouch functionalization. Functional pathway analysis of differentially expressed genes in the UC pouch revealed an enhanced state of immune/inflammatory response and extracellular matrix remodeling. Moreover, >70% of differentially expressed genes mapped to published inflammatory bowel diseases microarray data sets displayed directional changes consistent with active UC but not with Crohn's disease. Conclusions: The UC pouch, well before histologic inflammation, already displays a systems-level gain of colon-associated genes and loss of ileum-associated genes. Patients with UC exhibit a unique transcriptomic response to ileal pouch creation that can be observed well before disease and may in part explain their susceptibility to the development of pouchitis.

familial adenomatous polyposis↗

Slow thermalization and subdiffusion in $U$(1) conserving Floquet random circuits

Random quantum circuits are paradigmatic models of minimally structured and analytically tractable chaotic dynamics. We study a family of Floquet unitary circuits with Haar random U(1) charge conserving dynamics; the minimal such model has nearest-neighbor gates acting on spin-1/2 qubits, and a single layer of even/odd gates repeated periodically in time. We find that this minimal model is not robustly thermalizing at numerically accessible system sizes, and displays slow subdiffusive dynamics for long times. We map out the thermalization dynamics in a broader parameter space of charge conserving circuits, and understand the origin of the slow dynamics in terms of proximate localized and integrable regimes in parameter space. In contrast, we find that small extensions to the minimal model are sufficient to achieve robust thermalization; these include (i) increasing the interaction range to three-site gates, (ii) increasing the local Hilbert space dimension by appending an additional unconstrained qubit to the conserved charge on each site, or (iii) using a larger Floquet period comprised of two independent layers of gates. Furthermore, our results should inform future studies of charge conserving circuits, which are relevant for a wide range of topical theoretical questions.

1-dimensional spin chains↗

SU-E-T-279: Realization of Three-Dimensional Conformal Dose Planning in Prostate Brachytherapy

Purpose: Successful clinical treatment in prostate brachytherapy is largely dependent on the effectiveness of pre-surgery dose planning. Conventional dose planning method could hardly arrive at a satisfy result. In this abstract, a three-dimensional conformal localized dose planning method is put forward to ensure the accuracy and effectiveness of pre-implantation dose planning. Methods: Using Monte Carlo method, the pre-calculated 3-D dose map for single source is obtained. As for multiple seeds dose distribution, the maps are combined linearly to acquire the 3-D distribution. The 3-D dose distribution is exhibited in the form of isodose surface together with reconstructed 3-D organs group real-timely. Then it is possible to observe the dose exposure to target volume and normal tissues intuitively, thus achieving maximum dose irradiation to treatment target and minimum healthy tissues damage. In addition, the exfoliation display of different isodose surfaces can be realized applying multi-values contour extraction algorithm based on voxels. The needles could be displayed in the system by tracking the position of the implanted seeds in real time to conduct block research in optimizing insertion trajectory. Results: This study extends dose planning from two-dimensional to three-dimensional, realizing the three-dimensional conformal irradiation, which could eliminate the limitations of 2-D images and two-dimensional dose planning. A software platform is developed using VC++ and Visualization Toolkit (VTK) to perform dose planning. The 3-D model reconstruction time is within three seconds (on a Intel Core i5 PC). Block research could be conducted to avoid inaccurate insertion into sensitive organs or internal obstructions. Experiments on eight prostate cancer cases prove that this study could make the dose planning results more reasonable. Conclusion: The three-dimensional conformal dose planning method could improve the rationality of dose planning by safely reducing the large target margin and avoiding dose dead zones for prostate cancer treatment. 1) National Natural Science Foundation of People's Republic of China (No. 51175373); 2) New Century Educational Talents Plan of Chinese Education Ministry (NCET-10-0625); 3) Scientific and Technological Major Project, Tianjin (No. 12ZCDZSY10600)

60 APPLIED LIFE SCIENCES↗

Magnetotransport of Sm 2 Ir 2 O 7 across the pressure-induced quantum-critical phase boundary

Rare-earth pyrochlore iridates host two interlocking magnetic sublattices of corner-sharing tetrahedra and can harbour a unique combination of frustrated moments, exotic excitations and highly correlated electrons. They are also the first systems predicted to display both topological Weyl semimetal and axion insulator phases. We have measured the transport and magnetotransport properties of single-crystal Sm 2 Ir 2 O 7 up to and beyond the pressure-induced quantum critical point for all-in-all-out (AIAO) Ir order at $p_c$ = 63 kbar previously identified by resonant X-ray scattering and close to which Weyl semimetallic behavior has been previously predicted. Our findings overturn the accepted expectation that the suppression of AIAO order should lead to metallic conduction persisting down to zero temperature. Instead, the resistivity-minimum temperature, which tracks the decrease in the AIAO ordering temperature for pressures up to 30 kbar, begins to increase under further application of pressure, pointing to the presence of a second as-yet unidentified mechanism leading to non-metallic behavior. The magnetotransport does track the suppression of Ir magnetism, however, with a strong hysteresis observed only within the AIAO phase boundary, similar to that found for Ho 2 Ir 2 O 7 and attributed to plastic deformation of Ir domains. Around $p_c$ we find the emergence of a new type of electronic phase, characterized by a negative magnetoresistance with small hysteresis at the lowest temperatures, and hysteresis-free positive magnetoresistance above approximately 5 K. The temperature dependence of our low-temperature transport data are found to be best described by a model consistent with a Weyl semimetal across the entire pressure range.

36 MATERIALS SCIENCE↗

Angular magnetic field beam improves efficiency in klystrons and traveling wave tubes

Special lens shaping allows variation of focusing strength with radius. Lens can be either converging or diverging depending on charge of particles and direction of angular magnetic field. There is potential use for lens in particle analyzers, electron beam welding systems, microwave tube refocusing systems, and possible display type devices.

Neugebauer, W.↗

Wind-tunnel calibration and requirements for in-flight use of fixed hemispherical head angle-of-attack and angle-of-sideslip sensors

Wind-tunnel tests were conducted with three different fixed pressure-measuring hemispherical head sensor configurations which were strut-mounted on a nose boom. The tests were performed at free-stream Mach numbers from 0.2 to 3.6. The boom-angle-of-attack range was -6 to 15 deg, and the angle-of-sideslip range was -6 to 6 deg. The test Reynolds numbers were from 3.28 million to 65.6 million per meter. The results were used to obtain angle-of-attack and angle-of-sideslip calibration curves for the configurations. Signal outputs from the hemispherical head sensor had to be specially processed to obtain accurate real-time angle-of-attack and angle-of-sideslip measurements for pilot displays or aircraft systems. Use of the fixed sensors in flight showed them to be rugged and reliable and suitable for use in a high temperature environment.

Montoya, E. J.↗

Monitor weather conditions for cloud seeding control

The author has identified the following significant results. The near real-time DCS platform data transfer to the time-share compare is a working reality. Six stations are now being automatically monitored and displayed with a system delay of 3 to 8 hours from time of data transmission to time of data accessibility on the computer. The DCS platform system has proven itself a valuable tool for near real-time monitoring of mountain precipitation. Data from Wolf Creek Pass were an important input in making the decision when to suspend seeding operations to avoid exceeding suspension criteria in that area. The DCS platforms, as deployed in this investigation, have proven themselves to be reliable weather resistant systems for winter mountain environments in the southern Colorado mountains.

Kahan, A. M.↗

Reconnaissance of marine resources

A test area along the NW Coast of Africa was used during the Skylab mission to study the distribution of temperature and plankton. The S190B Earth Terrain Camera with a spectral film response of 0.4-0.7 micrometers allowed qualitative estimates of the distribution patterns of suspended material. Differentiation between inorganic particles and phytoplankton could be made by comparing the green band and the red band of the S190A Camera System. The pictorial display of data obtained from the S191 scanning radiometer in the 10-11 micrometer atmospheric window allowed a detailed interpretation of the temperature distribution in the area where cold upwelled water reaches the euphotic zone. The comparison between infrared data and the imageries taken simultaneously indicated the origin of the cold water as well as the pathway within the Canary current. A fish survey carried out almost simultaneously in the area, by echosounding, showed high correlation between the position of good fishing grounds and the distribution of plankton as detected by remote sensing detectors on Skylab.

Szekielda, K.-H.↗

Comparison of numeric keyboard and CRT line-labeled buttons for information access

Test were conducted to determine whether differences in speed and accuracy are experienced when using either line-labeled index buttons or a numeric keyboard for page selection in airborne CRT-display area navigation systems. The experiment was conducted with six airline pilots, each flying the same two simulated RNAV routes. Three pilot subjects used line-labeled buttons adjacent to the CRT screen, while three used a numeric keyboard for page access. The hypothesis of no differences in response times between the two modes of access could not be rejected.

Williams, D.↗

Deriving winds for hurricanes using short interval satellite imagery

Results are presented for a study program designed to develop a better means of obtaining wind data needed by hurricane forecasters and to determine the optimum space and time resolution of satellite data used to obtain such winds. The discussion covers cloud tracking with an image display and manipulation system and analysis of IR imagery of Hurricane Eloise. It is shown that greater resolution in time and space of satellite imagery made it possible to derive up to six times as many low-level winds in a hurricane case, to eliminate 'bad winds' caused by mistaking cloud growth for cloud motion, and to remove ambiguities that would have caused difficulty in tracking clouds using only the imagery taken at 30-min intervals. It is suggested to use short-interval imagery (less than 10 min) for wind determination for future research in areas of tropical cyclones.

Gentry, R. C.↗

Flight simulation - A vital and expanding technology in aircraft development

Flight simulation, both ground and in-flight, is experiencing major technological improvement and growth. The increased capabilities are providing new opportunities for support of the aircraft development process. The development of faster digital computers, improved visual displays, better motion systems and increased interest in simulation fidelity has improved the ground simulator to the point where it accomplishes a major portion of the aircraft development before work on the flight article begins. The efficiency of the ground simulator as a forecaster for the flight testing phase is becoming well established. In-flight simulation is properly being used to bridge the gap between the ground simulator and the flight test article. Simulation provides the vital link between analysis, aerodynamic tests, and subsystem tests and the flight test article. This paper describes the latest advances in flight simulation and its increasing role in the aircraft development process.

Reynolds, P. A.↗

Antitheft container for instruments

Antitheft container is used to prevent theft of calculators, portable computers, and other small instruments. Container design is simple and flexible enough to allow easy access to display or input systems of instruments, while not interfering with power input to device.

Kerley, J. J., Jr.↗

Utilizing the dust streak-dryline intersection phenomenon in severe local storm forecasting

Several characteristics of a major dust storm on 20 February 1976 are presented. Four primary areas of discussion are considered: dust storm characteristics; comparisons between the cell detection capabilities of the geosynchronous satellite and radar; the use of the NASA Atmospheric and Oceanographic Information Processing System (an interactive image processing system) for interactive display of visual and IR digital data to obtain qualitative and quantitative results on specific dust cloud and cloud top characteristics; and evidence that the intersection downwind of dust clouds (streaks) with the dryline can be used to forecast the initial storm development on the dryline and that the dust clouds detected on 20 February 1976 are a reflection of upper tropospheric speed maxima, which according to McNulty (1978) and others, are associated with rapid severe convective local storm development.

Anthony, R. W.↗

Advanced marine information delivery

The paper examines the information delivery challenges of the follow-on programs to Seasat-1 as they may progress through the next decade. These challenges include coping with the vast amounts of data to be transferred, fulfilling the temporal requirements on data delivery, and the tradeoffs and developments needed to accomplish the various levels of processing required to convert sensor output into useful information. A need for critical development is clearly identifiable in the areas of (1) low cost ground terminals capable of image extraction and image correlation; (2) dynamic data assimilation to accommodate forecasters; (3) low resolution onboard correlators; and (4) low cost user advisory (display) terminals. The system planners for the Ocean Satellite advanced programs are using an end-to-end data systems approach in meeting these challenges.

Durstenfeld, R.↗