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Modeling Logistics and Supportability for Crewed Missions Beyond Low Earth Orbit

NASA’s future missions aim to establish a sustained human presence on the lunar surface and send humans to Mars. These missions will send crews farther from home than previous missions, limiting the opportunities for resupply missions. Additionally, the use of multiple launches and reusable elements will increase mission and campaign complexity. Logistics and supportability analysis evaluates the link between mission and system characteristics and key metrics such as logistics and spares mass and volume, crew time, and risk. As missions become increasingly complex and crews are logistically isolated for longer periods of time, logistics and supportability will become more powerful drivers of risk and cost and, therefore, more important considerations during system and mission development. When logistics and supportability are considered from the beginning of system and mission development, opportunities arise to create more efficient, lower-risk systems. Design choices made without detailed consideration of logistics and supportability have the potential to result in greater risks and increased costs as all options may not have been analyzed. This paper provides an overview of a methodology used for space mission logistics and supportability analysis, including key metrics, assumptions, and required inputs. Example applications of this methodology to explore the impacts of system architecture, dormancy, and synergies between lunar and Mars missions are also presented. Conducting these holistic analyses enables informed decision-making for mission planning and system design, which can help mitigate the risk of loss of mission, vehicle, or crew. Using the knowledge of historical missions, experiences gained on the lunar surface, and logistics and supportability analyses, NASA can examine and optimize supportability characteristics for safer and more effective operations for future lunar and Mars missions.

Supportability↗

Modeling Logistics and Supportability for Crewed Missions Beyond Low Earth Orbit

NASA’s future missions aim to establish a sustained human presence on the lunar surface and send humans to Mars. These missions will send crews farther from home than previous missions, limiting the opportunities for resupply missions. Additionally, the use of multiple launches and reusable elements will increase mission and campaign complexity. Logistics and supportability analysis evaluates the link between mission and system characteristics and key metrics such as logistics and spares mass and volume, crew time, and risk. As missions become increasingly complex and crews are logistically isolated for longer periods of time, logistics and supportability will become more powerful drivers of risk and cost and, therefore, more important considerations during system and mission development. When logistics and supportability are considered from the beginning of system and mission development, opportunities arise to create more efficient, lower-risk systems. Design choices made without detailed consideration of logistics and supportability have the potential to result in greater risks and increased costs as all options may not have been analyzed. This paper provides an overview of a methodology used for space mission logistics and supportability analysis, including key metrics, assumptions, and required inputs. Example applications of this methodology to explore the impacts of system architecture, dormancy, and synergies between lunar and Mars missions are also presented. Conducting these holistic analyses enables informed decision-making for mission planning and system design, which can help mitigate the risk of loss of mission, vehicle, or crew. Using the knowledge of historical missions, experiences gained on the lunar surface, and logistics and supportability analyses, NASA can examine and optimize supportability characteristics for safer and more effective operations for future lunar and Mars missions.

Supportability↗

p53 deficiency alters the yield and spectrum of radiation-induced lacZ mutants in the brain of transgenic mice

Exposure to heavy particle radiation in the galacto-cosmic environment poses a significant risk in space exploration and the evaluation of radiation-induced genetic damage in tissues, especially in the central nervous system, is an important consideration in long-term manned space missions. We used a plasmid-based transgenic mouse model system, with the pUR288 lacZ transgene integrated in the genome of every cell of C57Bl/6(lacZ) mice, to evaluate the genetic damage induced by iron particle radiation. In order to examine the importance of genetic background on the radiation sensitivity of individuals, we cross-bred p53 wild-type lacZ transgenic mice with p53 nullizygous mice, producing lacZ transgenic mice that were either hemizygous or nullizygous for the p53 tumor suppressor gene. Animals were exposed to an acute dose of 1 Gy of iron particles and the lacZ mutation frequency (MF) in the brain was measured at time intervals from 1 to 16 weeks post-irradiation. Our results suggest that iron particles induced an increase in lacZ MF (2.4-fold increase in p53+/+ mice, 1.3-fold increase in p53+/- mice and 2.1-fold increase in p53-/- mice) and that this induction is both temporally regulated and p53 genotype dependent. Characterization of mutants based on their restriction patterns showed that the majority of the mutants arising spontaneously are derived from point mutations or small deletions in all three genotypes. Radiation induced alterations in the spectrum of deletion mutants and reorganization of the genome, as evidenced by the selection of mutants containing mouse genomic DNA. These observations are unique in that mutations in brain tissue after particle radiation exposure have never before been reported owing to technical limitations in most other mutation assays.

Non-NASA Center↗

Rejuvenation of Spent Media via Supported Emulsion Liquid Membranes

The overall goal of this project is to maximize the reuseability of spent fermentation media. Supported emulsion liquid membrane separation, a highly efficient extraction technique, is used to remove inhibitory byproducts during fermentation; thus, improving the yield while reducing the need for fresh water. The key objectives of this study are: Develop an emulsion liquid membrane system targeting low molecular weight organic acids which has minimal toxicity on a variety of microbial systems; Conduct mass transfer studies to allow proper modeling and design of a supported emulsion liquid membrane system; Investigate the effect of gravity on emulsion coalescence within the membrane unit; Access the effect of water re-use on fermentation yields in a model microbial system; Develop a perfusion-type fermentor utilizing a supported emulsion liquid membrane system to control inhibitory fermentation byproducts; Work for the coming year will focus on the determination of toxicity of various solvents, selection of the emulsifying agents, as well as characterizing the mass transfer of hollow-fiber contactors.

Wiencek, John M.↗

Physics of Reconnection and MMS Mission

Reconnection is the most important process driving the Earth's magnetosphere. Key to the success of the MMS science plan is the coupling of theory and observation. Determining the kinetic processes occurring in the diffusion region and physical parameters that control the rate of magnetic reconnection are among primary objectives of the MMS mission. Analysis of the role played by particle inertial effects in the diffusion region where the plasma is unmagnetized will be presented. The reconnection electric field in he diffusion region is supported primarily by particle non-gyrotropic effects. At the quasi-steady stage the reconnection electric field serves to accelerate and heat the incoming plasma population to maintain the current flow in the diffusion region the pressure balance. The primary mechanism controlling the dissipation in the vicinity of the reconnection site is incorporated into the fluid description in terms of non-gyrotropic corrections to the. induction and energy equations. The results of kinetic and fluid simulations illustrating the physics of magnetic reconnection will be presented. We will dem~:tistrate that kinetic nongyrotropic effects can significantly alter the global magnetosphere evolution and location of reconnection sites.

Kuznetsova, M. M.↗

Kinetic principles of interaction of components in complex biological systems

A biomathematical analysis of component interaction in biological systems is given. Two primary types of systems are discussed - open systems and closed systems. The applicability of these systems to life support equipment in spacecraft is analyzed and formulae are provided to demonstrate the effect (theoretical) of closed and open systems in life support systems.

Rubin, A. B.↗

NRIC EBR-II Test Bed Pre-Conceptual Design Report

Authorized by the Nuclear Energy Innovation Capabilities Act (NEICA), the National Reactor Innovation Center (NRIC) provides private sector technology developers access to strategic infrastructures and assets for commercial nuclear energy research, development, demonstration, and deployment activities. The mission is to support a timely and cost-effective path to the licensing and commercialization of new nuclear energy systems. To meet these needs, NRIC is developing two test beds at Idaho National Laboratory (INL). The ZPPR Test bed (ZTB) and the EBR-II Test bed (ETB). The EBR-II test bed will support the demonstration of systems that operate at less than 10 MWt. The baseline objective is for the EBR-II Dome to act as a safety significant containment structure capable of siting reactors that utilize Safeguards Category 4 material for operations. The major areas addressed in the pre-conceptual design include: • Installation of an access door • Electrical Power • Heat Removal • Ventilation in the Dome • Module handling system Along with the design for ETB a concept of operations (COP) has also been developed. The COP is intended to facilitate a common understanding of ideas, challenges, and issues. As systems continue to evolve in complexity System Engineers and Project Directors will utilize the COP to develop and sustain a common vision of the system for stakeholders.

11 NUCLEAR FUEL CYCLE AND FUEL MATERIALS↗

Adaptive response of slow and fast skeletal muscle in the monkey to spaceflight

Experiments were designed to determine the effects of the absence of weight support on hindlimb muscles of the monkey: an ankle flexor (tibialis anterior, TA), two ankle extensors (medical gastrocnemius, MG and soleus, SOL), and a knee extensor (vastus lateralis, VL). These experiments will be performed as part of the BION mission. The original project proposed to assess the effects of weightlessness in adult Rhesus monkeys which were to be flown on the Space Shuttle as part of SLS-3. Feasibility studies were carried out and a series of experiments were performed at NASA/Ames Research Center to assess the effects of a 21-day restraint period in the ESOP on muscle properties. The results of these studies are summarized.

Bodine-Fowler, Sue↗

The desktop interface in intelligent tutoring systems

The interface between an Intelligent Tutoring System (ITS) and the person being tutored is critical to the success of the learning process. If the interface to the ITS is confusing or non-supportive of the tutored domain, the effectiveness of the instruction will be diminished or lost entirely. Consequently, the interface to an ITS should be highly integrated with the domain to provide a robust and semantically rich learning environment. In building an ITS for ZetaLISP on a LISP Machine, a Desktop Interface was designed to support a programming learning environment. Using the bitmapped display, windows, and mouse, three desktops were designed to support self-study and tutoring of ZetaLISP. Through organization, well-defined boundaries, and domain support facilities, the desktops provide substantial flexibility and power for the student and facilitate learning ZetaLISP programming while screening the student from the complex LISP Machine environment. The student can concentrate on learning ZetaLISP programming and not on how to operate the interface or a LISP Machine.

Baudendistel, Stephen↗

Size of tuber propagule influences injury of 'Kennebec' potato plants by constant light

Chlorosis and necrotic spotting develop on the foliage of particular cultivars of potato (Solanum tuberosum L.) when grown under constant light. 'Kennebec', a cultivar severely injured by constant light when propagated from tissue-cultured plantlets, also was injured when plants were propagated from small tuber pieces (approximately 1 g). However, plants did not develop injury when propagated from large tuber pieces (approximately 100 g). Plants from large tuber pieces grew more rapidly than plants from small tuber pieces. The role of plant vigor and carbohydrate translocation in controlling injury development is discussed.

NASA Discipline Life Support Systems↗

Pulse energy dependence of subcellular dissection by femtosecond laser pulses

Precise dissection of cells with ultrashort laser pulses requires a clear understanding of how the onset and extent of ablation (i.e., the removal of material) depends on pulse energy. We carried out a systematic study of the energy dependence of the plasma-mediated ablation of fluorescently-labeled subcellular structures in the cytoskeleton and nuclei of fixed endothelial cells using femtosecond, near-infrared laser pulses focused through a high-numerical aperture objective lens (1.4 NA). We find that the energy threshold for photobleaching lies between 0.9 and 1.7 nJ. By comparing the changes in fluorescence with the actual material loss determined by electron microscopy, we find that the threshold for true material ablation is about 20% higher than the photobleaching threshold. This information makes it possible to use the fluorescence to determine the onset of true material ablation without resorting to electron microscopy. We confirm the precision of this technique by severing a single microtubule without disrupting the neighboring microtubules, less than 1 micrometer away. c2005 Optical Society of America.

Non-NASA Center↗

Stability and transient motion of a plain journal mounted in flexible damped supports

Results are presented for an extensive study of the influence of damped flexible supports on the stability-threshold speed of a symmetric rotor mounted in nonlinear fluid-film bearings. A stability analysis is conducted by applying the Routh criteria and calculating the damped eigenvalues of the system. Stability maps are given in dimensionless form for a range of support stiffness, damping, and mass ratios. The effect of rotor imbalance on the stability of rotor systems is examined, and it is shown that time transient orbits of shaft and support motions clearly indicate their dynamic behavior for both stable and unstable operating speeds. Simple design criteria are proposed for choosing the support stiffness and damping on the basis of rotor weight and journal clearance to promote optimum stability. It is concluded that the use of a flexible damped support system may increase the stability threshold of a plain journal bearing and that damper supports should promote smoother and quieter machine operation by suppressing oil whirl and attenuating unbalanced rotational forces.

Kirk, R. G.↗

Evaluation of Human Research Facility Ultrasound With the ISS Video System

Most medical equipment on the International Space Station (ISS) is manifested as part of the U.S. or the Russian medical hardware systems. However, certain medical hardware is also available as part of the Human Research Facility. The HRF and the JSC Medical Operations Branch established a Memorandum of Agreement for joint use of certain medical hardware, including the HRF ultrasound system, the only diagnostic imaging device currently manifested to fly on ISS. The outcome of a medical contingency may be changed drastically, or an unnecessary evacuation may be prevented, if clinical decisions are supported by timely and objective diagnostic information. In many higher-probability medical scenarios, diagnostic ultrasound is a first-choice modality or provides significant diagnostic information. Accordingly, the Clinical Care Capability Development Project is evaluating the HRF ultrasound system for its utility in relevant clinical situations on board ISS. For effective management of these ultrasound-supported ISS medical scenarios, the resulting data should be available for viewing and interpretation on the ground, and bidirectional voice communication should be readily available to allow ground experts (sonographers, physicians) to provide guidance to the Crew Medical Officer. It may also be vitally important to have the capability of real-time guidance via video uplink to the CMO-operator during an exam to facilitate the diagnosis in a timely fashion. In this document, we strove to verify that the HRF ultrasound video output is compatible with the ISS video system, identify ISS video system field rates and resolutions that are acceptable for varying clinical scenaiios, and evaluate the HRF ultrasound video with a commercial, off-the-shelf video converter, and compare it with the ISS video system.

Melton, Shannon↗

Lunar Surface Reference Missions: A Description of Human and Robotic Surface Activities

Most medical equipment to the International Space Station (ISS) is manisfested as part of the U.S. or the Russian medical hardware systems. However, certain medical hardware is also available as part of the Human Research Facility. The HRF and the JSC Medical Operations Branch established a Memorandum of Agreement for joint use of certain medical hardware, including the HRF ultrasound system, the only diagnostic imaging device currently manifested to fly on ISS. The outcome of a medical contingency may be changed drastically, or an unnecessary evacuation may be prevented, if clinical decisions are supported by timely and objective diagnostic information. In many higher-probability medical scenarios, diagnostic ultrasound is a first-choice modality or provides significant diagnostic information. Accordingly, the Clinical Care Capability Development Project is evaluating the HRF ultrasound system for its utility in relevant clinical siruations on board ISS. For effective management of these ultrasound-supported ISS medical scenarios, the resulting data should be available for viewing and interpretation on the ground, and bidirectional voice communication should be readily available to allow ground experts (sonographers, physicians) to provide guidance to the Crew Medical Officer. It may also be vitally important to have the capability of real-time guidance via video uplink to the CMO-opertor during an exam to facilitate the diagnosis in a timely fashion.

Duke, Michael B.↗

In-Flight Aeroelastic Stability of the Thermal Protection System on the NASA HIAD, Part I: Linear Theory

Conical shell theory and piston theory aerodynamics are used to study the aeroelastic stability of the thermal protection system (TPS) on the NASA Hypersonic Inflatable Aerodynamic Decelerator (HIAD). Structural models of the TPS consist of single or multiple orthotropic conical shell systems resting on several circumferential linear elastic supports. The shells in each model may have pinned (simply-supported) or elastically-supported edges. The Lagrangian is formulated in terms of the generalized coordinates for all displacements and the Rayleigh-Ritz method is used to derive the equations of motion. The natural modes of vibration and aeroelastic stability boundaries are found by calculating the eigenvalues and eigenvectors of a large coefficient matrix. When the in-flight configuration of the TPS is approximated as a single shell without elastic supports, asymmetric flutter in many circumferential waves is observed. When the elastic supports are included, the shell flutters symmetrically in zero circumferential waves. Structural damping is found to be important in this case. Aeroelastic models that consider the individual TPS layers as separate shells tend to flutter asymmetrically at high dynamic pressures relative to the single shell models. Several parameter studies also examine the effects of tension, orthotropicity, and elastic support stiffness.

Goldman, Benjamin D.↗

Development of a mobile research flight test support capability

This paper presents the approach taken by the NASA Western Aeronautical Test Range (WATR) of the Ames Research Center to develop and utilize mobile systems to satisfy unique real-time research flight test requirements of research projects such as the advanced fighter technology integration (AFTI)F-16, YAV-8B Harrier, F-18 high-alpha research vehicle (HARV), XV-15, and the UH-60 Black Hawk. The approach taken is cost-effective, staff efficient, technologically current, and provides a safe and effective research flight test environment to support a highly complex set of real-time requirements including the areas of tracking and data acquisition, communications (audio and video) and real-time processing and display, postmission processing, and command uplink. The development of this capability has been in response to the need for rapid deployment at varied site locations with full real-time computations and display capability. This paper will discuss the requirements, implementation and growth plan for mobile systems development within the NASA Western Aeronautical Test Range.

Rhea, Donald C.↗

Development of a mobile research flight test support capability

This paper presents the approach taken by the NASA Western Aeronautical Test Range (WATR) of the Ames Research Center (ARC) to develop and utilize mobile systems to satisfy unique real-time research flight test requirements of research projects such as the advanced fighter technology integration (AFTI) F-16, YAV-8B Harrier, F-18 high-alpha research vehicle (HARV), XV-15, and the UH-60 Black Hawk. The approach taken is cost-effective, staff efficient, technologically current, and provides a safe and effective research flight test environment to support a highly complex set of real-time requirements including the areas of tracking and data acquisition, communications (audio and video) and real-time processing and display, postmission processing, and command uplink. The development of this capability has been in response to the need for rapid deployment at varied site locations with full real-time comutation and display capability. This paper will discuss the requirements, implementation and growth plan for mobile systems development within the NASA Western Aeronautical Test Range.

Rhea, Donald C.↗