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At least 127 records · Page 7

Dark matter effective field theory and an application to vector dark matter

The Standard Model Effective Field Theory (SMEFT) and the Low Energy Effective Field Theory (LEFT) can be extended by adding additional spin 0, 1/2 and 1 dark matter particles which are singlets under the Standard Model (SM) gauge group. We classify all gauge invariant interactions in the Lagrangian up to terms of dimension six, and present the tree-level matching conditions between the two theories at the electroweak scale. The most widely studied dark matter models, such as those based on the Higgs portal or on kinetic mixing between the photon and a dark photon, are based on dimension-four interactions with the SM sector. We consider a model with dark vector particles with a $\mathbb{Z}_2$ symmetry, so that the lightest dark matter particle is stable. The leading interaction with the SM is through dimension-six operators involving two dark vector field-strength tensors and the electromagnetic field-strength tensor. This model is a viable dark matter model in the freeze-in scenario for a wide range of parameters.

71 CLASSICAL AND QUANTUM MECHANICS, GENERAL PHYSIC↗

Search for pair production of vector-like quarks in leptonic final states in proton-proton collisions at $ \sqrt{s} $ = 13 TeV

A search is presented for vector-like T and B quark-antiquark pairs produced in proton-proton collisions at a center-of-mass energy of 13 TeV. Data were collected by the CMS experiment at the CERN LHC in 2016–2018, with an integrated luminosity of 138 fb$^{−1}$. Events are separated into single-lepton, same-sign charge dilepton, and multi-lepton channels. In the analysis of the single-lepton channel a multilayer neural network and jet identification techniques are employed to select signal events, while the same-sign dilepton and multilepton channels rely on the high-energy signature of the signal to distinguish it from standard model backgrounds. The data are consistent with standard model background predictions, and the production of vector-like quark pairs is excluded at 95% confidence level for T quark masses up to 1.54 TeV and B quark masses up to 1.56 TeV, depending on the branching fractions assumed, with maximal sensitivity to decay modes that include multiple top quarks. The limits obtained in this search are the strongest limits to date for $ \textrm{T}\overline{\textrm{T}} $ production, excluding masses below 1.48 TeV for all decays to third generation quarks, and are the strongest limits to date for $ \textrm{B}\overline{\textrm{B}} $ production with B quark decays to tW.[graphic not available: see fulltext]

72 PHYSICS OF ELEMENTARY PARTICLES AND FIELDS↗

Search for vector-like leptons with long-lived particle decays in the CMS muon system in proton-proton collisions at $$\sqrt{\text{s}}$$ = 13 TeV

Abstract A first search is presented for vector-like leptons (VLLs) exclusively decaying into a light long-lived pseudoscalar boson and a standard model τ lepton. The pseudoscalar boson is assumed to have a mass below the τ + τ − threshold, so that it decays exclusively into two photons. It is identified using the CMS muon system. The analysis is carried out using a data set of proton-proton collisions at a center-of-mass energy of 13 TeV collected by the CMS experiment in 2016–2018, corresponding to an integrated luminosity of 138 fb −1. Selected events contain at least one pseudoscalar boson decaying electromagnetically in the muon system and at least one hadronically decaying τ lepton. No significant excess of data events is observed compared to the background expectation. Upper limits are set at 95% confidence level on the vector-like lepton production cross section as a function of the VLL mass and the pseudoscalar boson mean proper decay length. The observed and expected exclusion ranges of the VLL mass extend up to 700 and 670 GeV, respectively, depending on the pseudoscalar boson lifetime.

Chekhovsky, V. [Yerevan Physics Institute]↗

Modelling and computational improvements to the simulation of single vector-boson plus jet processes for the ATLAS experiment

This paper presents updated Monte Carlo configurations used to model the production of single electroweak vector bosons (W, Z/γ$^{∗}$) in association with jets in proton-proton collisions for the ATLAS experiment at the Large Hadron Collider. Improvements pertaining to the electroweak input scheme, parton-shower splitting kernels and scale-setting scheme are shown for multi-jet merged configurations accurate to next-to-leading order in the strong and electroweak couplings. The computational resources required for these set-ups are assessed, and approximations are introduced resulting in a factor three reduction of the per-event CPU time without affecting the physics modelling performance. Continuous statistical enhancement techniques are introduced by ATLAS in order to populate low cross-section regions of phase space and are shown to match or exceed the generated effective luminosity. This, together with the lower per-event CPU time, results in a 50% reduction in the required computing resources compared to a legacy set-up previously used by the ATLAS collaboration. The set-ups described in this paper will be used for future ATLAS analyses and lay the foundation for the next generation of Monte Carlo predictions for single vector-boson plus jets production.[graphic not available: see fulltext]

72 PHYSICS OF ELEMENTARY PARTICLES AND FIELDS↗

Search for vector-like leptons with long-lived particle decays in the CMS muon system in proton-proton collisions at $\sqrt{s}$ = 13 TeV

A first search is presented for vector-like leptons (VLLs) exclusively decaying into a light long-lived pseudoscalar boson and a standard model τ lepton. The pseudoscalar boson is assumed to have a mass below the τ + τ − threshold, so that it decays exclusively into two photons. It is identified using the CMS muon system. The analysis is carried out using a data set of proton-proton collisions at a center-of-mass energy of 13 TeV collected by the CMS experiment in 2016–2018, corresponding to an integrated luminosity of 138 fb −1 . Selected events contain at least one pseudoscalar boson decaying electromagnetically in the muon system and at least one hadronically decaying τ lepton. No significant excess of data events is observed compared to the background expectation. Upper limits are set at 95% confidence level on the vector-like lepton production cross section as a function of the VLL mass and the pseudoscalar boson mean proper decay length. The observed and expected exclusion ranges of the VLL mass extend up to 700 and 670 GeV, respectively, depending on the pseudoscalar boson lifetime.

72 PHYSICS OF ELEMENTARY PARTICLES AND FIELDS↗

Search for $t$-channel scalar and vector leptoquark exchange in the high-mass dimuon and dielectron spectra in proton-proton collisions at $\sqrt{s}=13$ TeV

A search for t-channel exchange of leptoquarks (LQs) is performed in dimuon and dielectron spectra using proton-proton collision data collected at $\sqrt{s}=13$ TeV with the CMS detector at the CERN LHC. The data correspond to an integrated luminosity of 138 fb −1 . Eight scenarios are considered, in which up or down quarks couple to muons or electrons via a scalar or vector LQ exchange, for dilepton invariant masses above 500 GeV. The LQ masses are probed up to 5 TeV, beyond a regime probed by previous pair-production and single-production searches. The differential distributions of dilepton events are fit to templates that model the nonresonant LQ exchange and various standard model background processes. Limits are set on LQ-fermion coupling strengths for scalar and vector LQ masses in the 1–5 TeV range at 95% confidence level, establishing stringent limits on first- and second-generation LQs.

72 PHYSICS OF ELEMENTARY PARTICLES AND FIELDS↗

DOME: Directional medical embedding vectors from Electronic Health Records

Motivation: The increasing availability of Electronic Health Record (EHR) systems has created enormous potential for translational research. Recent developments in representation learning techniques have led to effective large-scale representations of EHR concepts along with knowledge graphs that empower downstream EHR studies. However, most existing methods require training with patient-level data, limiting their abilities to expand the training with multi-institutional EHR data. On the other hand, scalable approaches that only require summary-level data do not incorporate temporal dependencies between concepts. Methods: We introduce a DirectiOnal Medical Embedding (DOME) algorithm to encode temporally directional relationships between medical concepts, using summary-level EHR data. Specifically, DOME first aggregates patient-level EHR data into an asymmetric co-occurrence matrix. Then it computes two Positive Pointwise Mutual Information (PPMI) matrices to correspondingly encode the pairwise prior and posterior dependencies between medical concepts. Following that, a joint matrix factorization is performed on the two PPMI matrices, which results in three vectors for each concept: a semantic embedding and two directional context embeddings. They collectively provide a comprehensive depiction of the temporal relationship between EHR concepts. Results: We highlight the advantages and translational potential of DOME through three sets of validation studies. First, DOME consistently improves existing direction-agnostic embedding vectors for disease risk prediction in several diseases, for example achieving a relative gain of 5.5% in the area under the receiver operating characteristic (AUROC) for lung cancer. Second, DOME excels in directional drug-disease relationship inference by successfully differentiating between drug side effects and indications, correspondingly achieving relative AUROC gain over the state-of-the-art methods by 10.8% and 6.6%. Finally, DOME effectively constructs directional knowledge graphs, which distinguish disease risk factors from comorbidities, thereby revealing disease progression trajectories. The source codes are provided at https://github.com/celehs/Directional-EHRembedding.

60 APPLIED LIFE SCIENCES↗

Measurement of the associated production of a Higgs boson decaying into b-quarks with a vector boson at high transverse momentum in pp collisions at s=13 TeV with the ATLAS detector

The associated production of a Higgs boson with a W or Z boson decaying into leptons and where the Higgs boson decays to a $b\bar{b}$ pair is measured in the high vector-boson transverse momentum regime, above 250 GeV, with the ATLAS detector. The analysed data, corresponding to an integrated luminosity of 139 fb -1 , were collected in proton–proton collisions at the Large Hadron Collider between 2015 and 2018 at a centre-of-mass energy of $\sqrt{s}$ = 13 TeV. The measured signal strength, defined as the ratio of the measured signal yield to that predicted by the Standard Model, is $0.72^{+0.39}_{-0.36}$ corresponding to an observed (expected) significance of 2.1 (2.7) standard deviations. Cross-sections of associated production of a Higgs boson decaying into b quark pairs with a W or Z gauge boson, decaying into leptons, are measured in two exclusive vector boson transverse momentum regions, 250–400 GeV and above 400 GeV, and interpreted as constraints on anomalous couplings in the framework of a Standard Model effective field theory.

72 PHYSICS OF ELEMENTARY PARTICLES AND FIELDS↗

Search for pair-production of vector-like quarks in pp collision events at s = 13 TeV with at least one leptonically decaying Z boson and a third-generation quark with the ATLAS detector

Herein a search for the pair-production of vector-like quarks optimized for decays into a Z boson and a third-generation Standard Model quark is presented, using the full Run 2 dataset corresponding to 139fb –1 of pp collisions at $\sqrt{s}$ = 13TeV, collected in 2015–2018 with the ATLAS detector at the Large Hadron Collider. The targeted final state is characterized by the presence of a Z boson with high transverse momentum, reconstructed from a pair of same-flavour leptons with opposite-sign charges, as well as by the presence of b-tagged jets and high-transverse-momentum large-radius jets reconstructed from calibrated smaller-radius jets. Events with exactly two or at least three leptons are used, which are further categorized by the presence of boosted W, Z, and Higgs bosons and top quarks. The categorization is performed using a neural-network-based boosted object tagger to enhance the sensitivity to signal relative to the background. No significant excess above the background expectation is observed and exclusion limits at 95% confidence level are set on the masses of the vector-like partners T and B of the top and bottom quarks, respectively. The limits depend on the branching ratio configurations and, in the case of 100% branching ratio for T→Zt and 100% branching ratio for B→Zb, this search sets the most stringent limits to date, allowing m T >1.60TeV and m B >1.42TeV, respectively.

72 PHYSICS OF ELEMENTARY PARTICLES AND FIELDS↗

Combination of searches for singly and doubly charged Higgs bosons produced via vector-boson fusion in proton–proton collisions at s = 13 TeV with the ATLAS detector

A combination of searches for singly and doubly charged Higgs bosons, H ± and H ±± , produced via vector-boson fusion is performed using 140 fb -1 of proton–proton collisions at a centre-of-mass energy of 13 TeV, collected with the ATLAS detector during Run 2 of the Large Hadron Collider. Searches targeting decays to massive vector bosons in leptonic final states (electrons or muons) are considered. New constraints are reported on the production cross-section times branching fraction for charged Higgs boson masses between 200 GeV and 3000 GeV. The results are interpreted in the context of the Georgi-Machacek model for which the most stringent constraints to date are set for the masses considered in the combination.

72 PHYSICS OF ELEMENTARY PARTICLES AND FIELDS↗

Robust Biaxial Anisotropy and Switchable Néel Vectors in LaFeO 3 Epitaxial Films

Antiferromagnets with highly stable but switchable Néel vectors are desired for antiferromagnetic spintronics with ultrafast speed and terahertz frequencies. Electrical switching of antiferromagnetic insulators has been demonstrated using binary antiferromagnets, while large families of complex antiferromagnets such as perovskites are largely unexplored. Here, we show that epitaxial LaFeO 3 thin films on SrTiO 3 (001) exhibit clear, robust biaxial anisotropy with a spin-flop field of a few tesla. Angular-dependent spin-Hall magnetoresistance (SMR) characterizations of Pt/LaFeO 3 bilayers with the current channel along SrTiO 3 [100] and [110] reveal distinct, intriguing shapes and field dependence. Simulations using a macrospin model accurately describe the main behavior and fine features of the SMR data from which key antiferromagnetic parameters are extracted. Furthermore, remanent SMR measurement confirms the high fidelity of the Néel vector along either easy axis of the biaxial anisotropy, indicating that epitaxial films of LaFeO 3 and potentially other perovskite antiferromagnets offer an attractive platform for antiferromagnetic spintronics.

71 CLASSICAL AND QUANTUM MECHANICS, GENERAL PHYSIC↗

CRISPR/Cas9 as an antiviral against Orthopoxviruses using an AAV vector

A vaccine for smallpox is no longer administered to the general public, and there is no proven, safe treatment specific to poxvirus infections, leaving people susceptible to infections by smallpox and other zoonotic Orthopoxviruses such as monkeypox. Using vaccinia virus (VACV) as a model organism for other Orthopoxviruses, CRISPR–Cas9 technology was used to target three essential genes that are conserved across the genus, including A17L, E3L, and I2L. Three individual single guide RNAs (sgRNAs) were designed per gene to facilitate redundancy in rendering the genes inactive, thereby reducing the reproduction of the virus. The efficacy of the CRISPR targets was tested by transfecting human embryonic kidney (HEK293) cells with plasmids encoding both SaCas9 and an individual sgRNA. This resulted in a reduction of VACV titer by up to 93.19% per target. Following the verification of CRISPR targets, safe and targeted delivery of the VACV CRISPR antivirals was tested using adeno-associated virus (AAV) as a packaging vector for both SaCas9 and sgRNA. Similarly, AAV delivery of the CRISPR antivirals resulted in a reduction of viral titer by up to 92.97% for an individual target. Overall, we have identified highly specific CRISPR targets that significantly reduce VACV titer as well as an appropriate vector for delivering these CRISPR antiviral components to host cells in vitro.

60 APPLIED LIFE SCIENCES↗

Predicting distribution of malaria vector larval habitats in Ethiopia by integrating distributed hydrologic modeling with remotely sensed data

Abstract Larval source management has gained renewed interest as a malaria control strategy in Africa but the widespread and transient nature of larval breeding sites poses a challenge to its implementation. To address this problem, we propose combining an integrated high resolution (50 m) distributed hydrological model and remotely sensed data to simulate potential malaria vector aquatic habitats. The novelty of our approach lies in its consideration of irrigation practices and its ability to resolve complex ponding processes that contribute to potential larval habitats. The simulation was performed for the year of 2018 using ParFlow-Common Land Model (CLM) in a sugarcane plantation in the Oromia region, Ethiopia to examine the effects of rainfall and irrigation. The model was calibrated using field observations of larval habitats to successfully predict ponding at all surveyed locations from the validation dataset. Results show that without irrigation, at least half of the area inside the farms had a 40% probability of potential larval habitat occurrence. With irrigation, the probability increased to 56%. Irrigation dampened the seasonality of the potential larval habitats such that the peak larval habitat occurrence window during the rainy season was extended into the dry season. Furthermore, the stability of the habitats was prolonged, with a significant shift from semi-permanent to permanent habitats. Our study provides a hydrological perspective on the impact of environmental modification on malaria vector ecology, which can potentially inform malaria control strategies through better water management.

59 BASIC BIOLOGICAL SCIENCES↗

Complete Stokes vector analysis with a compact, portable rotating waveplate polarimeter

Accurate calibration of polarization dependent optical elements is often necessary in optical experiments. A versatile polarimeter device to measure the polarization state of light is a valuable tool in these experiments. Here we report a rotating waveplate-based polarimeter capable of complete Stokes vector analysis of collimated light. Calibration of the device allows accurate measurements over a range of wavelengths, with a bandwidth of >30 nm in this implementation. A photo-interrupter trigger system supplies the phase information necessary for full determination of the Stokes vector. An Arduino microcontroller performs rapid analysis and displays the results on a liquid crystal display. The polarimeter is compact and can be placed anywhere on an optical table on a single standard post. The components to construct the device are only a fraction of the cost of commercially available devices while the accuracy and precision of the measurements are of the same order of magnitude.

47 OTHER INSTRUMENTATION↗

Theory and application of the vector pair correlation function for real-space crystallographic analysis of order/disorder correlations from STEM images

Deviations of local structure and chemistry from the average crystalline unit cell are increasingly recognized to have a significant influence on the properties of many technologically important materials. Here, we present the vector pair correlation function (vPCF) as a new real-space crystallographic analysis method, which can be applied to atomic-resolution scanning transmission electron microscopy (STEM) images to quantify and analyze structural order/disorder correlations. Our STEM-based vPCFs have several advantages over radial PCFs and/or 3D pair distribution functions from x-ray total scattering: vPCFs explicitly retain crystallographic orientation information, are spatially resolved, can be applied directly on a sublattice basis, and are suitable for any material that can be imaged with STEM. To show the utility of our approach, we measure partial vPCFs in Ba 5 SmSn 3 Nb 7 O 30 (BSSN), a tetragonal tungsten bronze (TTB) structured complex oxide. Many TTBs are known to be classical or relaxor ferroelectrics, and these properties have been correlated with the presence of superlattice ordering. BSSN, specifically, exhibits relaxor behavior and an incommensurate structural modulation. From the vPCF data, we observe that, of the cation sites, only the Ba (A2) sublattice is structurally modulated. We then infer the local modulation vector and reveal a marked anisotropy in its correlation length. Finally, short-range correlated polar displacements on the B2 cation sites are observed. This work introduces the vPCF as a powerful real-space crystallography technique, which enables direct, robust quantification of short-to-long range order on a sublattice-specific basis and is applicable to a wide range of complex material types.

37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CH↗

Generalized Korn’s inequalities for piecewise $H¹$ and $H²$ vector fields

The purpose of this paper is to construct a new class of discrete generalized Korn’s inequalities for piecewise $H^1$ vector fields and piecewise $H^2$ vector fields in three-dimensional space. The resulting Korn’s inequalities are different from the standard Korn’s inequalities, as they involve the trace-free symmetric gradient operator, in place of the usual symmetric gradient operator. Furthermore, it is anticipated that the new generalized Korn’s inequalities will be useful for the analysis of a broad range of finite element methods, including mixed finite element methods and discontinuous Galerkin methods.

97 MATHEMATICS AND COMPUTING↗

Sensitivity to longitudinal vector boson scattering and doubly charged Higgs boson production in $W^± W^± jj$ at future hadron colliders

We study the sensitivity to longitudinal vector boson scattering at a 27-, 50-, and 100-TeV pp collider using events containing two leptonically decaying same-electric-charge 𝑊 bosons produced in association with two jets. The baseline FCC-hh detector parametrization within the D ELPHES framework is used under the assumption of fully efficient pileup mitigation. A tightly constrained phase space with a dijet mass greater than 2 TeV is considered in order to suppress the impact of potential instrumental backgrounds. Based on this setup, the expected sensitivity to the production of longitudinally polarized same-sign 𝑊 boson pairs is evaluated. Additionally, expected limits are set on doubly charged Higgs bosons produced via vector boson fusion processes and decaying to same-sign 𝑊 boson pairs.

72 PHYSICS OF ELEMENTARY PARTICLES AND FIELDS↗

Nucleon axial-vector form factor and radius from radiatively corrected antineutrino scattering data

The nucleon axial-vector form factor, 𝐺 𝐴 , is critical to determine the electroweak interactions of leptons with nucleons. Important examples of processes influenced by 𝐺 𝐴 are elastic (anti)neutrino-nucleon scattering and muon capture by the proton. Sparse experimental data results in a large uncertainty on the momentum dependence of 𝐺 𝐴 and has motivated the consideration of new experimental probes and first-principles lattice quantum chromodynamics (QCD) evaluations. The comparison of new and precise theoretical predictions for 𝐺 𝐴 with future experimental data necessitates the application of radiative corrections to experimentally observable processes. We apply these corrections in the extraction of 𝐺 𝐴 and the associated axial-vector radius from the recent MINERvA antineutrino-hydrogen data, compare the effects from radiative corrections to other uncertainties in neutrino scattering experiments, and discuss the comparison of lattice QCD evaluations to experimental measurements.

72 PHYSICS OF ELEMENTARY PARTICLES AND FIELDS↗