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At least 127 records · Page 7

Analyzing the Subjectivity of Hole-Type Image Quality Indicators for Radiography

Hole-type penetrameters used as image quality indicators (IQIs) for radiography have an inherent degree of subjectivity to their interpretation. The 1T (one times the thickness of the penetrameter) hole is so small, it can be difficult to distinguish from noise. It is suspected that an operator’s knowledge of the true location of the 1T hole may subconsciously influence a false positive identification of the 1T hole when in fact it cannot be discerned. In the case of computed radiography (CR), the size of the phosphor particles may lead to a noise pattern with features on the scale of the 1T hole. Per NASA-STD-5009, the 1T hole must be detected in order to achieve adequate sensitivity. This is based on the historical understanding that this sensitivity will enable detection of the minimum detectable flaw sizes listed in the standard. It’s important to understand if 1T sensitivity is being achieved, and the associated risk if not. This study sought to determine the true detectability of 1T-sized holes in aluminum and Inconel by creating and inspecting a set of penetrameters with randomly placed holes. Enough holes and vacant zones were created to enable a full probability of detection study with 90% detectability, 95% confidence. Testing is ongoing, but preliminary results have shown poor detectability. The detection rate is slightly better for Inconel than aluminum, slightly better using a micro-focus vs. mini-focus tube, and definitively better for film than CR. One of the key questions of this study is whether historical requirements for film are applicable for CR, and these initial findings suggest they may not be. There is also a requirement in the NASA standard for the minimum contrast-to-noise ratio of the hole. The results have shown that this numerical threshold does not correlate well with visual detection. This raises questions about the true nature of detection, in an age of image processing vs. human judgement. As the results indicate that the detection of 1T holes is unreliable, the next challenge will be determining what sensitivity is really achieved, and what is needed.

Erin Lanigan↗

Analyzing the Subjectivity of Hole-Type Image Quality Indicators for Radiography

Hole-type penetrameters used as image quality indicators (IQIs) for radiography have an inherent degree of subjectivity to their interpretation. The 1T (one times the thickness of the penetrameter) hole is so small, it can be difficult to distinguish from noise. It is suspected that an operator’s knowledge of the true location of the 1T hole may subconsciously influence a false positive identification of the 1T hole when in fact it cannot be discerned. In the case of computed radiography (CR), the size of the phosphor particles may lead to a noise pattern with features on the scale of the 1T hole. Per NASA-STD-5009, the 1T hole must be detected in order to achieve adequate sensitivity. This is based on the historical understanding that this sensitivity will enable detection of the minimum detectable flaw sizes listed in the standard. It’s important to understand if 1T sensitivity is being achieved, and the associated risk if not. This study sought to determine the true detectability of 1T-sized holes in aluminum and Inconel by creating and inspecting a set of penetrameters with randomly placed holes. Enough holes and vacant zones were created to enable a full probability of detection study with 90% detectability, 95% confidence. Testing is ongoing, but preliminary results have shown poor detectability. The detection rate is slightly better for Inconel than aluminum, slightly better using a micro-focus vs. mini-focus tube, and definitively better for film than CR. One of the key questions of this study is whether historical requirements for film are applicable for CR, and these initial findings suggest they may not be. There is also a requirement in the NASA standard for the minimum contrast-to-noise ratio of the hole. The results have shown that this numerical threshold does not correlate well with visual detection. This raises questions about the true nature of detection, in an age of image processing vs. human judgement. As the results indicate that the detection of 1T holes is unreliable, the next challenge will be determining what sensitivity is really achieved, and what is needed.

Erin Lanigan↗

Quality control for quantitative multicenter whole-body PET/MR studies: A NEMA image quality phantom study with three current PET/MR systems

Purpose: Integrated positron emission tomography/magnetic resonance (PET/MR) systems derive the PET attenuation correction (AC) from dedicated MR sequences. While MR-AC performs reasonably well in clinical patient imaging, it may fail for phantom-based quality control (QC). The authors assess the applicability of different protocols for PET QC in multicenter PET/MR imaging. Methods: The National Electrical Manufacturers Association NU 2 2007 image quality phantom was imaged on three combined PET/MR systems: a Philips Ingenuity TF PET/MR, a Siemens Biograph mMR, and a GE SIGNA PET/MR (prototype) system. The phantom was filled according to the EANM FDG-PET/CT guideline 1.0 and scanned for 5 min over 1 bed. Two MR-AC imaging protocols were tested: standard clinical procedures and a dedicated protocol for phantom tests. Depending on the system, the dedicated phantom protocol employs a two-class (water and air) segmentation of the MR data or a CT-based template. Differences in attenuation- and SUV recovery coefficients (RC) are reported. PET/CT-based simulations were performed to simulate the various artifacts seen in the AC maps (μ-map) and their impact on the accuracy of phantom-based QC. Results: Clinical MR-AC protocols caused substantial errors and artifacts in the AC maps, resulting in underestimations of the reconstructed PET activity of up to 27%, depending on the PET/MR system. Using dedicated phantom MR-AC protocols, PET bias was reduced to −8%. Mean and max SUV RC met EARL multicenter PET performance specifications for most contrast objects, but only when using the dedicated phantom protocol. Simulations confirmed the bias in experimental data to be caused by incorrect AC maps resulting from the use of clinical MR-AC protocols. Conclusions: Phantom-based quality control of PET/MR systems in a multicenter, multivendor setting may be performed with sufficient accuracy, but only when dedicated phantom acquisition and processing protocols are used for attenuation correction.

60 APPLIED LIFE SCIENCES↗

A high quality image compression scheme for real-time applications

Many image compression or coding techniques have been developed to reduce the amount of bits of information needed to represent digital images. Among these, Vector Quantization (VQ) seems to have the edge; its theoretical distortion is lower than that of other block coding techniques at comparable bit rates. However, the application of Vector Quantization remains limited due to its high computational complexity. Presently, it is limited to low to medium quality image compression. In this paper it is shown that VQ can be mapped onto VLSI implementation via systolic type architecture, making real time application possible. In addition, it is shown that using multistage or cascade VQ high quality images can be obtained at very low bit rates for real time applications while using smaller codebooks than is necessary in single stage VQ. Examples of processed images are presented.

Ramamoorthy, P. A.↗

Thematic Mapper image quality - Registration, noise, and resolution

The Landsat-4 satellite has two new imaging radiometers, including the redesigned Multispectral Scanner (MSS) and the Thematic Mapper (TM). The present investigation is concerned with an assessment of TM image quality on the basis of a study of band-to-band registration, periodic noise, and spatial resolution. In the TM images analyzed, the band-to-band registration accuracy of the instrument is very good. A few imperfections were found. Once a stable misregistration is removed, the TM should also meet its registration specifications between focal planes. Spatial resolution analyses in terms of MTF were performed in comparison modes. The forward and backward scans were shown to have virtually identical MTFs.

Wrigley, R. C.↗

Optical array for high-quality imaging in harsh environments

Methods and apparatus are disclosed for producing high quality images in uncontrolled or impaired environments. In some examples of the disclosed technology, groups of cameras for high dynamic range (HDR), polarization diversity, and optional other diversity modes are arranged to concurrently image a common scene. For example, in a vehicle checkpoint application, HDR provides discernment of dark objects inside a vehicle, while polarization diversity aids in rejecting glare. Spectral diversity, infrared imaging, and active illumination can be applied for better imaging through a windshield. Preprocessed single-camera images are registered and fused. Faces or other features of interest can be detected in the fused image and identified in a library. Impairments can include weather, insufficient or interfering lighting, shadows, reflections, window glass, occlusions, or moving objects.

42 ENGINEERING↗

Optical array for high-quality imaging in harsh environments

Methods and apparatus are disclosed for producing high quality images in uncontrolled or impaired environments. In some examples of the disclosed technology, groups of cameras for high dynamic range (HDR), polarization diversity, and optional other diversity modes are arranged to concurrently image a common scene. For example, in a vehicle checkpoint application, HDR provides discernment of dark objects inside a vehicle, while polarization diversity aids in rejecting glare. Spectral diversity, infrared imaging, and active illumination can be applied for better imaging through a windshield. Preprocessed single-camera images are registered and fused. Faces or other features of interest can be detected in the fused image and identified in a library. Impairments can include weather, insufficient or interfering lighting, shadows, reflections, window glass, occlusions, or moving objects.

Baba, Justin S.↗

Improved image quality in pinhole SPECT by accurate modeling of the point spread function in low magnification systems

Purpose: Single photon emission computed tomography (SPECT) has become an important noninvasive imaging technique in small-animal research. Due to the high resolution required in small-animal SPECT systems, the spatially variant system response needs to be included in the reconstruction algorithm. Accurate modeling of the system response should result in a major improvement in the quality of reconstructed images. The aim of this study was to quantitatively assess the impact that an accurate modeling of spatially variant collimator/detector response has on image-quality parameters, using a low magnification SPECT system equipped with a pinhole collimator and a small gamma camera. Methods: Three methods were used to model the point spread function (PSF). For the first, only the geometrical pinhole aperture was included in the PSF. For the second, the septal penetration through the pinhole collimator was added. In the third method, the measured intrinsic detector response was incorporated. Tomographic spatial resolution was evaluated and contrast, recovery coefficients, contrast-to-noise ratio, and noise were quantified using a custom-built NEMA NU 4–2008 image-quality phantom. Results: A high correlation was found between the experimental data corresponding to intrinsic detector response and the fitted values obtained by means of an asymmetric Gaussian distribution. For all PSF models, resolution improved as the distance from the point source to the center of the field of view increased and when the acquisition radius diminished. An improvement of resolution was observed after a minimum of five iterations when the PSF modeling included more corrections. Contrast, recovery coefficients, and contrast-to-noise ratio were better for the same level of noise in the image when more accurate models were included. Ring-type artifacts were observed when the number of iterations exceeded 12. Conclusions: Accurate modeling of the PSF improves resolution, contrast, and recovery coefficients in the reconstructed images. To avoid the appearance of ring-type artifacts, the number of iterations should be limited. In low magnification systems, the intrinsic detector PSF plays a major role in improvement of the image-quality parameters.

46 INSTRUMENTATION RELATED TO NUCLEAR SCIENCE AND ↗

SU-E-J-02: 4D Digital Tomosynthesis Based On Algebraic Image Reconstruction and Total-Variation Minimization for the Improvement of Image Quality

Purpose: In this paper, we implemented the four-dimensional (4D) digital tomosynthesis (DTS) imaging based on algebraic image reconstruction technique and total-variation minimization method in order to compensate the undersampled projection data and improve the image quality. Methods: The projection data were acquired as supposed the cone-beam computed tomography system in linear accelerator by the Monte Carlo simulation and the in-house 4D digital phantom generation program. We performed 4D DTS based upon simultaneous algebraic reconstruction technique (SART) among the iterative image reconstruction technique and total-variation minimization method (TVMM). To verify the effectiveness of this reconstruction algorithm, we performed systematic simulation studies to investigate the imaging performance. Results: The 4D DTS algorithm based upon the SART and TVMM seems to give better results than that based upon the existing method, or filtered-backprojection. Conclusion: The advanced image reconstruction algorithm for the 4D DTS would be useful to validate each intra-fraction motion during radiation therapy. In addition, it will be possible to give advantage to real-time imaging for the adaptive radiation therapy. This research was supported by Leading Foreign Research Institute Recruitment Program (Grant No.2009-00420) and Basic Atomic Energy Research Institute (BAERI); (Grant No. 2009-0078390) through the National Research Foundation of Korea(NRF) funded by the Ministry of Science, ICT and Future Planning (MSIP)

62 RADIOLOGY AND NUCLEAR MEDICINE↗

Model-based quantification of image quality

In 1982, Park and Schowengerdt published an end-to-end analysis of a digital imaging system quantifying three principal degradation components: (1) image blur - blurring caused by the acquisition system, (2) aliasing - caused by insufficient sampling, and (3) reconstruction blur - blurring caused by the imperfect interpolative reconstruction. This analysis, which measures degradation as the square of the radiometric error, includes the sample-scene phase as an explicit random parameter and characterizes the image degradation caused by imperfect acquisition and reconstruction together with the effects of undersampling and random sample-scene phases. In a recent paper Mitchell and Netravelli displayed the visual effects of the above mentioned degradations and presented subjective analysis about their relative importance in determining image quality. The primary aim of the research is to use the analysis of Park and Schowengerdt to correlate their mathematical criteria for measuring image degradations with subjective visual criteria. Insight gained from this research can be exploited in the end-to-end design of optical systems, so that system parameters (transfer functions of the acquisition and display systems) can be designed relative to each other, to obtain the best possible results using quantitative measurements.

Hazra, Rajeeb↗

TH-CD-207B-12: Quantification of Clinical Feedback On Image Quality Differences Between Two CT Scanner Models

Purpose: This work sought to quantify a radiology team’s assessment of image quality differences between two CT scanner models currently in clinical use, with emphasis on noise and low-contrast detectability (LCD). Methods: A water phantom and a Kagaku anthropomorphic body phantom were scanned on GE Discovery CT750 HD and LightSpeed VCT scanners (4 each) with identical scan parameters and reconstructed to 2.5mm/5.0mm thicknesses. Images of water phantom were analyzed at the scanner console with a built-in LCD tool that uses statistical methods to compute requisite CT-number contrast for 95% confidence in detection of a user-defined object size. LCD value was computed for 5mm, 3mm, and 1mm objects. Analysis of standard deviation and LCD values were performed on Kagaku phantom images within liver, stomach, and spleen. LCD value was computed for 4mm, 3mm, and 1mm objects using a benchmarked MATLAB implementation of the GE scanner-console tool. Results: Water LCD values were larger (poorer performance) for all HD scanners compared to VCT scanners. Mean scanner model difference in requisite CT-number contrast for 5mm, 3mm, and 1mm objects for 5.0mm/2.5mm images was 3.0%/3.4% (p=0.02/p=0.10), 5.3%/5.7% (0.00002/0.02), and 8.5%/8.2% (0.0004/0.002), respectively. Mean standard deviations within Kagaku phantom ROIs were greater in HD compared to VCT images, with mean differences for the liver, stomach, and spleen for 5.0mm/2.5mm of 16%/12% (p=0.04/0.10), 8%/12% (0.15/0.11), and 16%/15% (0.05/0.11), respectively. Mean LCD value difference between HD and VCT scanners over all ROIs for 4mm, 3m, and 1mm objects and 5.0mm/2.5mm was 34%/9%, 16%/8%, and 18%/10%, respectively. HD scanners outperformed VCT scanners only for the 4mm stomach object. Conclusion: Using both water and anthropomorphic phantoms, it was shown that HD scanners are outperformed by VCT scanners with respect to noise and LCD in a consistent and in most cases statistically significant manner. The relationship between statistical and clinical significance demands further work.

60 APPLIED LIFE SCIENCES↗

SU-F-I-46: Optimizing Dose Reduction in Adult Head CT Protocols While Maintaining Image Quality in Postmortem Head Scans

Purpose: To optimize adult head CT protocol by reducing dose to an appropriate level while providing CT images of diagnostic quality. Methods: Five cadavers were scanned from the skull base to the vertex using a routine adult head CT protocol (120 kVp, 270 mA, 0.75 s rotation, 0.5 mm × 32 detectors, 70.8 mGy CTDIvol) followed by seven reduced-dose protocols with varying combinations of reduced tube current, reduced rotation time, and increased detectors with CTDIvol ranging from 38.2 to 65.6 mGy. Organ doses were directly measured with 21 OSL dosimeters placed on the surface and implanted in the head by a neurosurgeon. Two neuroradiologists assessed grey-white matter differentiation, fluid space, ventricular size, midline shift, brain mass, edema, ischemia, and skull fractures on a three point scale: (1) Unacceptable, (2) Borderline Acceptable, and (3) Acceptable. Results: For the standard scan, doses to the skin, lens of the eye, salivary glands, thyroid, and brain were 37.55 mGy, 49.65 mGy, 40.67 mGy, 4.63 mGy, and 27.33 mGy, respectively. Two cadavers had cerebral edema due to changing dynamics of postmortem effects, causing the grey-white matter differentiation to appear less distinct. Two cadavers with preserved grey-white matter received acceptable scores for all image quality features for the protocol with a CTDIvol of 57.3 mGy, allowing organ dose savings ranging from 34% to 45%. One cadaver allowed for greater dose reduction for the protocol with a CTDIvol of 42 mGy. Conclusion: Efforts to optimize scan protocol should consider both dose and clinical image quality. This is made possible with postmortem subjects, whose brains are similar to patients, allowing for an investigation of ideal scan parameters. Radiologists at our institution accepted scan protocols acquired with lower scan parameters, with CTDIvol values closer to the American College of Radiology’s (ACR) Achievable Dose level of 57 mGy.

60 APPLIED LIFE SCIENCES↗

Use of local noise power spectrum and wavelet analysis in quantitative image quality assurance for EPIDs

Purpose: To investigate the use of local noise power spectrum (NPS) to characterize image noise and wavelet analysis to isolate defective pixels and inter-subpanel flat-fielding artifacts for quantitative quality assurance (QA) of electronic portal imaging devices (EPIDs). Methods: A total of 93 image sets including custom-made bar-pattern images and open exposure images were collected from four iViewGT a-Si EPID systems over three years. Global quantitative metrics such as modulation transform function (MTF), NPS, and detective quantum efficiency (DQE) were computed for each image set. Local NPS was also calculated for individual subpanels by sampling region of interests within each subpanel of the EPID. The 1D NPS, obtained by radially averaging the 2D NPS, was fitted to a power-law function. The r-square value of the linear regression analysis was used as a singular metric to characterize the noise properties of individual subpanels of the EPID. The sensitivity of the local NPS was first compared with the global quantitative metrics using historical image sets. It was then compared with two commonly used commercial QA systems with images collected after applying two different EPID calibration methods (single-level gain and multilevel gain). To detect isolated defective pixels and inter-subpanel flat-fielding artifacts, Haar wavelet transform was applied on the images. Results: Global quantitative metrics including MTF, NPS, and DQE showed little change over the period of data collection. On the contrary, a strong correlation between the local NPS (r-square values) and the variation of the EPID noise condition was observed. The local NPS analysis indicated image quality improvement with the r-square values increased from 0.80 ± 0.03 (before calibration) to 0.85 ± 0.03 (after single-level gain calibration) and to 0.96 ± 0.03 (after multilevel gain calibration), while the commercial QA systems failed to distinguish the image quality improvement between the two calibration methods. With wavelet analysis, defective pixels and inter-subpanel flat-fielding artifacts were clearly identified as spikes after thresholding the inversely transformed images. Conclusions: The proposed local NPS (r-square values) showed superior sensitivity to the noise level variations of individual subpanels compared with global quantitative metrics such as MTF, NPS, and DQE. Wavelet analysis was effective in detecting isolated defective pixels and inter-subpanel flat-fielding artifacts. The proposed methods are promising for the early detection of imaging artifacts of EPIDs.

60 APPLIED LIFE SCIENCES↗

Image quality, space-qualified UV interference filters

The progress during the contract period is described. The project involved fabrication of image quality, space-qualified bandpass filters in the 200-350 nm spectral region. Ion-assisted deposition (IAD) was applied to produce stable, reasonably durable filter coatings on space compatible UV substrates. Thin film materials and UV transmitting substrates were tested for resistance to simulated space effects.

Mooney, Thomas A.↗

Technical Note: Phantom study to evaluate the dose and image quality effects of a computed tomography organ-based tube current modulation technique

Purpose: This technical note quantifies the dose and image quality performance of a clinically available organ-dose-based tube current modulation (ODM) technique, using experimental and simulation phantom studies. The investigated ODM implementation reduces the tube current for the anterior source positions, without increasing current for posterior positions, although such an approach was also evaluated for comparison. Methods: Axial CT scans at 120 kV were performed on head and chest phantoms on an ODM-equipped scanner (Optima CT660, GE Healthcare, Chalfont St. Giles, England). Dosimeters quantified dose to breast, lung, heart, spine, eye lens, and brain regions for ODM and 3D-modulation (SmartmA) settings. Monte Carlo simulations, validated with experimental data, were performed on 28 voxelized head phantoms and 10 chest phantoms to quantify organ dose and noise standard deviation. The dose and noise effects of increasing the posterior tube current were also investigated. Results: ODM reduced the dose for all experimental dosimeters with respect to SmartmA, with average dose reductions across dosimeters of 31% (breast), 21% (lung), 24% (heart), 6% (spine), 19% (eye lens), and 11% (brain), with similar results for the simulation validation study. In the phantom library study, the average dose reduction across all phantoms was 34% (breast), 20% (lung), 8% (spine), 20% (eye lens), and 8% (brain). ODM increased the noise standard deviation in reconstructed images by 6%–20%, with generally greater noise increases in anterior regions. Increasing the posterior tube current provided similar dose reduction as ODM for breast and eye lens, increased dose to the spine, with noise effects ranging from 2% noise reduction to 16% noise increase. At noise equal to SmartmA, ODM increased the estimated effective dose by 4% and 8% for chest and head scans, respectively. Increasing the posterior tube current further increased the effective dose by 15% (chest) and 18% (head) relative to SmartmA. Conclusions: ODM reduced dose in all experimental and simulation studies over a range of phantoms, while increasing noise. The results suggest a net dose/noise benefit for breast and eye lens for all studied phantoms, negligible lung dose effects for two phantoms, increased lung dose and/or noise for eight phantoms, and increased dose and/or noise for brain and spine for all studied phantoms compared to the reference protocol.

60 APPLIED LIFE SCIENCES↗

Notes on Synthetic Aperture Radar Image Quality

Synthetic Aperture Radar (SAR) creates an image of a target scene by coherently processing radar echo returns collected along a flightpath. The quality of the SAR image is inextricably linked to the utility of the image for exploitation supporting the task at hand. Aspects of quality include the fidelity with which it can render the scene being imaged, to include the system’s Impulse Response (IPR) and underlying noise levels/characteristics. Other factors also impact utility.

47 OTHER INSTRUMENTATION↗