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At least 127 records · Page 7

Movement Limitation and Immune Responses of Rhesus Monkeys

The effects of restraint on immunological parameters was determined in an 18 day ARRT (adult rhesus restraint test). The monkeys were restrained for 18 days in the experimental station for the orbiting primate (ESOP), the chair of choice for Space Shuttle experiments. Several immunological parameters were determined using peripheral blood, bone marrow, and lymph node specimens from the monkeys. The parameters included: response of bone marrow cells to GM-CSF (granulocyte-macrophage colony stimulating factor), leukocyte subset distribution, and production of IFN-alpha (interferon-alpha) and IFN-gamma (interferon-gamma). The only parameter changed after 18 days of restraint was the percentage of CDB+ T cells. No other immunological parameters showed changes due to restraint. Handling and changes in housing prior to the restraint period did apparently result in some restraint-independent immunological changes. Handling must be kept to a minimum and the animals allowed time to recover prior to flight. All experiments must be carefully controlled. Restraint does not appear to be a major issue regarding the effects of space flight on immune responses.

Sonnenfeld, Gerald↗

Urban Environment Initiative

The Urban Environment Initiative (UEI), has been established as part of a Cooperative Agreement with the National Aeronautics and Space Administration (NASA). The UEI is part of NASA's overall High Performance Computing and Communications (HPCC) and the Information Infrastructure Technology Applications (IITA) programs. The goal of the UEI is to provide public access to Earth Science information and promote its use with a focus on the environment of urban areas. This goal will be accomplished through collaborative efforts of the UEI team with both community-based and local/regional governmental organizations. The UEI team is comprised of four organizations representing private industry, NASA, and universities: Prime Technologies Service Corporation, NASA's Minority University Space Interdisciplinary Network (MU-SPIN) California State University, at Los Angeles, and Central State University (Wilberforce, OH). "Urban Environment" refers to the web of environmental, economic, and social factors that combine to create the urban world in which we live. Examples of these factors are population distribution, neighborhood demographic profiles, economic resources, business activities, location and concentration of environmental hazards and various pollutants, proximity and level of urban services, which form the basis of the urban environment and ultimately affect our lives and experiences. The use of Geographic Information Systems (GIS) and remote sensing allows data to be visualized in the forms of maps and spatial images. The use of these tools allow analysis of information about urban environments. Also included are descriptions of the four query types which will assist in understanding the maps.

Source record↗

Investigation of Near Shannon Limit Coding Schemes

Turbo codes can deliver performance that is very close to the Shannon limit. This report investigates algorithms for convolutional turbo codes and block turbo codes. Both coding schemes can achieve performance near Shannon limit. The performance of the schemes is obtained using computer simulations. There are three sections in this report. First section is the introduction. The fundamental knowledge about coding, block coding and convolutional coding is discussed. In the second section, the basic concepts of convolutional turbo codes are introduced and the performance of turbo codes, especially high rate turbo codes, is provided from the simulation results. After introducing all the parameters that help turbo codes achieve such a good performance, it is concluded that output weight distribution should be the main consideration in designing turbo codes. Based on the output weight distribution, the performance bounds for turbo codes are given. Then, the relationships between the output weight distribution and the factors like generator polynomial, interleaver and puncturing pattern are examined. The criterion for the best selection of system components is provided. The puncturing pattern algorithm is discussed in detail. Different puncturing patterns are compared for each high rate. For most of the high rate codes, the puncturing pattern does not show any significant effect on the code performance if pseudo - random interleaver is used in the system. For some special rate codes with poor performance, an alternative puncturing algorithm is designed which restores their performance close to the Shannon limit. Finally, in section three, for iterative decoding of block codes, the method of building trellis for block codes, the structure of the iterative decoding system and the calculation of extrinsic values are discussed.

Kwatra, S. C.↗

An XMM-Newton Monitoring Campaign of the Accretion Flow in IGRJ16318-4848

This grant is associated to a successful XMM-Newton-AO3 observational proposal to monitor the spectrum of the X-ray loud component of the recently discovered binary system IGR J16138-4848, to study the conditions of the accretion flows (and their evolution) in binary system. All four EPIC-PN and MOS observations of the target have now been performed (the last one of the 4, only 3 months ago). The four observations were logarithmically spaced, so to cover timescales from days to months. Data from all four pointings have now been reduced, using the XMM-Newton data reduction pipeline, and spectra and lightcurves from the target have been extracted. For the first three observations we have already performed the observation-by-observation data analysis, by fitting the single EPIC spectra with spectral models that include an intrinsic continuum power law (reduced at low energy by neutral absorption), a 6.4 keV iron emission line (detected in all spectra with varying intensity) and a Compton-reflection component. A Compton reflection component is also detected in all spectra, although at lower significance. The analysis of the fourth and last observation of our monitoring campaign has just recently begun. Next, we will (1) stack together the four observations of IGR J16138-4848, to obtain high-accuracy estimates of the average spectral parameters of this object; and then (2) proceed to the time-evolving analysis, of the three spectral parameters: (a) Gamma (the slope of the intrinsic continuum), (b) W(FeK), the equivalent width of the 6.4 keV Iron emission line, and (c) R, the relative amount of Compton reflection. Through this time-resolved spectroscopic analysis we hope to constrain (a) the physical state of the accreting matter and its relation with the X-ray output, and (b) the evolution of the accretion flow geometry, distribution and covering factor.

Mushotzky, Richard↗

The NANOGrav Nine-Year Data Set: Limits on the Isotropic Stochastic Gravitational Wave Background

We compute upper limits on the nanohertz-frequency isotropic stochastic gravitational wave background (GWB) using the 9 year data set from the North American Nanohertz Observatory for Gravitational Waves (NANOGrav) collaboration. Well-tested Bayesian techniques are used to set upper limits on the dimensionless strain amplitude (at a frequency of 1 yr(exp -1) for a GWB from supermassive black hole binaries of A(sub gw) less than 1.5 x 10(exp -15). We also parameterize the GWB spectrum with a broken power-law model by placing priors on the strain amplitude derived from simulations of Sesana and McWilliams et al. Using Bayesian model selection we find that the data favor a broken power law to a pure power law with odds ratios of 2.2 and 22 to one for the Sesana and McWilliams prior models, respectively. Using the broken power-law analysis we construct posterior distributions on environmental factors that drive the binary to the GW-driven regime including the stellar mass density for stellar-scattering, mass accretion rate for circumbinary disk interaction, and orbital eccentricity for eccentric binaries, marking the first time that the shape of the GWB spectrum has been used to make astrophysical inferences. Returning to a power-law model, we place stringent limits on the energy density of relic GWs, OMEGA(sub gw) (f) h squared less than 4.2 x 10(exp -10). Our limit on the cosmic string GWB, OMEGA(sub gw) (f) h squared less than 2.2 x 10(exp -10), translates to a conservative limit on the cosmic string tension with G mu less than 3.3 x 10(exp -8), a factor of four better than the joint Planck and high-l‚ cosmic microwave background data from other experiments.

Arzoumanian, Z.↗

Impedance Matching a Quarter Wave Resonant Receiver to Improve Efficiency in Unipolar Capacitive Wireless Power Transfer

Impedance matching techniques to achieve high performance in conventional wireless power transfer (WPT) systems are well established. These WPT systems are modelled as a lumped circuit, where the voltages/currents are approximately uniform and mostly unaffected by parasitic elements. However, a group of WPT techniques exist that utilize parasitic elements to form a highly resonant power transfer condition at high quality factors, exploiting a distributed circuit operation that can be modeled as a mutually coupled transmission line. A calculated matching network typically becomes unmatched when connected to the transmission line, as it changes the electrical structure of the coupled transmission line. This is particularly true for WPT systems that use quarter wave (QWR) or half wave resonators (HWR) for the receiver. Here we present one technique of matching to a mutually coupled transmission line where a parallel path is formed that improves the power transfer efficiency without severely altering the transmission line characteristics.

Wireless↗

Automated generation of influence functions for planar crack problems

A numerical procedure for the generation of influence functions for Mode I planar problems is described. The resulting influence functions are in a form for convenient evaluation of stress-intensity factors for complex stress distributions. Crack surface displacements are obtained by a least-squares solution of the Williams eigenfunction expansion for displacements in a cracked body. Discrete values of the influence function, evaluated using the crack surface displacements, are curve fit using an assumed functional form. The assumed functional form includes appropriate limit-behavior terms for very deep and very shallow cracks. Continuous representation of the influence function provides a convenient means for evaluating stress-intensity factors for arbitrary stress distributions by numerical integration. The procedure is demonstrated for an edge-cracked strip and a radially cracked disk. Comparisons with available published results demonstrate the accuracy of the procedure.

Sire, Robert A.↗

Dependence of Aerosol Light Absorption and Single-Scattering Albedo On Ambient Relative Humidity for Sulfate Aerosols with Black Carbon Cores

Atmospheric aerosols frequently contain hygroscopic sulfate species and black carbon (soot) inclusions. In this paper we report results of a modeling study to determine the change in aerosol absorption due to increases in ambient relative humidity (RH), for three common sulfate species, assuming that the soot mass fraction is present as a single concentric core within each particle. Because of the lack of detailed knowledge about various input parameters to models describing internally mixed aerosol particle optics, we focus on results that were aimed at determining the maximum effect that particle humidification may have on aerosol light absorption. In the wavelength range from 450 to 750 nm, maximum absorption humidification factors (ratio of wet to 'dry=30% RH' absorption) for single aerosol particles are found to be as large as 1.75 when the RH changes from 30 to 99.5%. Upon lesser humidification from 30 to 80% RH, absorption humidification for single particles is only as much as 1.2, even for the most favorable combination of initial ('dry') soot mass fraction and particle size. Integrated over monomodal lognormal particle size distributions, maximum absorption humidification factors range between 1.07 and 1.15 for humidification from 30 to 80% and between 1.1 and 1.35 for humidification from 30 to 95% RH for all species considered. The largest humidification factors at a wavelength of 450 nm are obtained for 'dry' particle size distributions that peak at a radius of 0.05 microns, while the absorption humidification factors at 700 nm are largest for 'dry' size distributions that are dominated by particles in the radius range of 0.06 to 0.08 microns. Single-scattering albedo estimates at ambient conditions are often based on absorption measurements at low RH (approx. 30%) and the assumption that aerosol absorption does not change upon humidification (i.e., absorption humidification equal to unity). Our modeling study suggests that this assumption alone can introduce absolute errors in estimates of the midvisible single-scattering albedo of up to 0.05 for realistic dry particle size distributions. Our study also indicates that this error increases with increasing wavelength. The potential errors in aerosol single-scattering albedo derived here are comparable in magnitude and in addition to uncertainties in single-scattering albedo estimates that are based on measurements of aerosol light absorption and scattering.

Redemann, Jens↗

Constraining the High-Energy Emission from Gamma-Ray Bursts with Fermi

We examine 288 GRBs detected by the Fermi Gamma-ray Space Telescope's Gamma-ray Burst Monitor (GBM) that fell within the field-of-view of Fermi's Large Area Telescope (LAT) during the first 2.5 years of observations, which showed no evidence for emission above 100 MeV. We report the photon flux upper limits in the 0.1-10 GeV range during the prompt emission phase as well as for fixed 30 s and 100 s integrations starting from the trigger time for each burst. We compare these limits with the fluxes that would be expected from extrapolations of spectral fits presented in the first GBM spectral catalog and infer that roughly half of the GBM-detected bursts either require spectral breaks between the GBM and LAT energy bands or have intrinsically steeper spectra above the peak of the nuF(sub v) spectra (E(sub pk)). In order to distinguish between these two scenarios, we perform joint GBM and LAT spectral fits to the 30 brightest GBM-detected bursts and find that a majority of these bursts are indeed softer above E(sub pk) than would be inferred from fitting the GBM data alone. Approximately 20% of this spectroscopic subsample show statistically significant evidence for a cut-off in their high-energy spectra, which if assumed to be due to gamma gamma attenuation, places limits on the maximum Lorentz factor associated with the relativistic outflow producing this emission. All of these latter bursts have maximum Lorentz factor estimates that are well below the minimum Lorentz factors calculated for LAT-detected GRBs, revealing a wide distribution in the bulk Lorentz factor of GRB outflows and indicating that LAT-detected bursts may represent the high end of this distribution.

Gehrels, Neil↗

X-ray studies of BL Lacertae objects with the Einstein Observatory - Confrontation with the synchrotron self-Compton predictions

X-ray flux densities measured with the Einstein Observatory are presented for a set of LB Lac objects with available VLBI angular sizes. The static, single-component synchrotron self-Compton formalism is used to predict the X-ray flux densities. Ratios of 10 to the -6th to the 10 to the -8th are found for the observed to predicted flux densities and it is concluded that such a model, at least in its simplest form, does not explain the X-ray emission from these objects as a class. The hypothesis that the compact source is in relativistic motion allows a simple resolution of the discrepancy. The results agree qualitatively with a broad distribution of bulk Lorentz factors Gamma with a fairly low typical value of Gamma approximately equal to and with a quasi-isotropic distribution of the direction of ejection relative to our line of sight.

Madejski, G. M.↗

Matching Experimental And Analytical Aerodynamic Data

Three methods of calculating correction factors developed to match steady lifting distributions of pressure, forces and moments on airfoil sections, and total forces and moments. Data for rectangular supercritical wing tested in NASA Langley Research Center Transonic Dynamics Tunnel used to determine correction factors to match distributions of surface pressure for mach numbers ranging from 0.266 to 0.8. These correction factors also applied to calculations of unsteady aerodynamic flow, and comparisons made with oscillatory experimental data for range of reduced frequencies at several mach numbers. Methods of combining analytical and experimental data should lead to more-accurate predictions of performance of airfoils. Also applied to such airfoils as those in gas-turbine engines, fans, and wind turbines.

Wieseman, Carol D.↗

Probabilistic simulation of stress concentration in composite laminates

A computational methodology is described to probabilistically simulate the stress concentration factors in composite laminates. This new approach consists of coupling probabilistic composite mechanics with probabilistic finite element structural analysis. The probabilistic composite mechanics is used to probabilistically describe all the uncertainties inherent in composite material properties while probabilistic finite element is used to probabilistically describe the uncertainties associated with methods to experimentally evaluate stress concentration factors such as loads, geometry, and supports. The effectiveness of the methodology is demonstrated by using it to simulate the stress concentration factors in composite laminates made from three different composite systems. Simulated results match experimental data for probability density and for cumulative distribution functions. The sensitivity factors indicate that the stress concentration factors are influenced by local stiffness variables, by load eccentricities and by initial stress fields.

Chamis, C. C.↗

Presenting the Rain-Sea Interaction Facility

The new Rain-Sea Interaction Facility (RSIF) was established at GSFC/WFF and the first finds are presented. The unique feature of this laboratory is the ability to systematically study microwave scattering from a water surface roughened by artificial rain, for which the droplets are at terminal velocity. The fundamental instruments and systems (e.g., the rain simulator, scatterometers, and surface elevation probes) were installed and evaluated during these first experiments - so the majority of the data were obtained with the rain simulator at 1 m above the water tank. From these initial experiments, three new models were proposed: the square-root function for NCS vs. R, the log Gaussian model for ring-wave elevation frequency spectrum, and the Erland probability density distribution for back scattered power. Rain rate is the main input for these models, although the coefficients may be dependent upon other factors (drop-size distribution, fall velocity, radar configuration, etc.). The facility is functional and we foresee collaborative studies with investigators who are engaged in measuring and modeling rain-sea interaction processes.

Bliven, Larry F.↗

Global distribution and migration of subsurface ice on Mars

An analytical model is developed for the factors which changed the initial distribution and state of H2O, mainly trapped as subsurface ice, on Mars. A uniform initial ice distribution is assumed, and changes in ice layer thickness are calculated at discrete latitudes of Mars. The thermal/diffusive model used for the calculations accounts for variations in the solar luminosity, the planetary obliquity and eccentricity, with obliquity starting 3.5 Gyr ago, and insolation at various latitudes. Attention is given to variations in the albedo due to seasonal CO2 variations, in the regolith temperature, and in atmospheric pressure. Migration of H2O into and out of the regolith is a function of the H2O vapor temperature at the subsurface ice boundary and the annual average H2O at the base of the atmosphere. Projections of the ice thickness over 100 obliquity periods indicate that the intensity of the obliquity effects are latitudinally dependent. H2O atmospheric concentrations are projected to vary up to six orders of magnitude over an obliquity cycle.

Fanale, F. P.↗

Luminosity distributions for Virgo cluster galaxies. I Near-infrared surface photometry of 81 disk systems

I-band (8500 A) surface photometry of 81 galaxies in Virgo provides the basis for comparing the disk properties of S0 galaxies with those of Sa, Sb, and Sc systems. No significant difference is found in the distributions of either central surface brightness or exponential scale length between S0's and later Hubble types. Because the I-band is dominated by contributions from the old-disk population, this result suggests that the factors which control the distribution of luminous disk material in all types of disk systems are identical. Evidently, environmental factors have not played a significant role in affecting the star-forming histories of the Virgo disks.

Boroson, T. A.↗

Airplane spinning.

Aircraft spinning problems, noting mass distribution and tail design factors for satisfactory spin recovery characteristics

AIRCRAFT CONSTRUCTION↗

Ten-fold augmentation of endothelial uptake of vascular endothelial growth factor with ultrasound after systemic administration

OBJECTIVES: In this study, the feasibility of delivering and enhancing the uptake of vascular endothelial growth factor (VEGF) into the intact endothelium by using ultrasound (US) facilitation was determined. BACKGROUND: A limitation of tissue-targeted drug delivery is the need for direct arterial cannulation. We postulate a mechanism by which agents injected intravenously may be targeted to a tissue using US and ultrasonic contrast agents. METHODS: We used a rat model to test the ability of US and an ultrasonic contrast agent perflurocarbon exposed sonicated dextrose albumin (PESDA) to increase uptake of VEGF in the myocardium. Continuous wave Doppler US (0.6 W/cm2 at 1 MHz for 15 min) was applied to the chest wall overlying the myocardium during intravenous injection with either VEGF (100 microg/kg) alone or a combination of VEGF and PESDA (0.1%). Control rats had VEGF infused without US or PESDA. The VEGF uptake was measured quantitatively in the heart, lung, liver and kidneys by enzyme-linked immunosorbent assay (ng/g of tissue) and morphologically by fluorescence microscopy. RESULTS: There was an eight-fold increase in VEGF uptake in the heart by US alone (16.86 +/- 1.56 vs. 2.11 +/- 0.953 ng/g of tissue, p < 0.0001) and a 13-fold increase with US + PESDA (26.78 +/- 2.88 vs. 2.11 +/- 0.953 ng/g of tissue, p < 0.0001) compared with control rats. Fluorescence microscopy revealed deposition of VEGF in the endothelium of small intramyocardial arterioles. CONCLUSIONS: These results show a marked increase in endothelial VEGF uptake with US and US + PESDA. Thus, US may be used to augment endothelial VEGF uptake 10-fold to 13-fold.

Non-NASA Center↗

Improving Search Algorithms by Using Intelligent Coordinates

We consider algorithms that maximize a global function G in a distributed manner, using a different adaptive computational agent to set each variable of the underlying space. Each agent eta is self-interested; it sets its variable to maximize its own function g (sub eta). Three factors govern such a distributed algorithm's performance, related to exploration/exploitation, game theory, and machine learning. We demonstrate how to exploit alI three factors by modifying a search algorithm's exploration stage: rather than random exploration, each coordinate of the search space is now controlled by a separate machine-learning-based player engaged in a noncooperative game. Experiments demonstrate that this modification improves simulated annealing (SA) by up to an order of magnitude for bin packing and for a model of an economic process run over an underlying network. These experiments also reveal interesting small-world phenomena.

Wolpert, David H.↗