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At least 127 records · Page 7

H0LiCOW – IV. Lens mass model of HE 0435-1223 and blind measurement of its time-delay distance for cosmology

Strong gravitational lenses with measured time delays between the multiple images allow a direct measurement of the time-delay distance to the lens, and thus a measure of cosmological parameters, particularly the Hubble constant, H0. We present a blind lens model analysis of the quadruply imaged quasar lens HE 0435-1223 using deep Hubble Space Telescope imaging, updated time-delay measurements from the COSmological MOnitoring of GRAvItational Lenses (COSMOGRAIL), a measurement of the velocity dispersion of the lens galaxy based on Keck data, and a characterization of the mass distribution along the line of sight. HE 0435-1223 is the third lens analysed as a part of the H0 Lenses in COSMOGRAIL's Wellspring (H0LiCOW) project. We account for various sources of systematic uncertainty, including the detailed treatment of nearby perturbers, the parametrization of the galaxy light and mass profile, and the regions used for lens modelling. We constrain the effective time-delay distance to be D Δt =2612$+208\atop{-191}$Mpc, a precision of 7.6 per cent. From HE 0435-1223 alone, we infer a Hubble constant of H 0 =73.1$+5.7\atop{-6.0}$kms -1 Mpc -1 assuming a flat ΛCDM cosmology. Lastly, the cosmographic inference based on the three lenses analysed by H0LiCOW to date is presented in a companion paper (H0LiCOW Paper V).

79 ASTRONOMY AND ASTROPHYSICS↗

H0LiCOW XII. Lens mass model of WFI2033 − 4723 and blind measurement of its time-delay distance and H0

ABSTRACT We present the lens mass model of the quadruply-imaged gravitationally lensed quasar WFI2033 − 4723, and perform a blind cosmographical analysis based on this system. Our analysis combines (1) time-delay measurements from 14 yr of data obtained by the COSmological MOnitoring of GRAvItational Lenses (COSMOGRAIL) collaboration, (2) high-resolution Hubble Space Telescope imaging, (3) a measurement of the velocity dispersion of the lens galaxy based on ESO-MUSE data, and (4) multi-band, wide-field imaging and spectroscopy characterizing the lens environment. We account for all known sources of systematics, including the influence of nearby perturbers and complex line-of-sight structure, as well as the parametrization of the light and mass profiles of the lensing galaxy. After unblinding, we determine the effective time-delay distance to be $4784_{-248}^{+399}~\mathrm{Mpc}$, an average precision of $6.6{{\ \rm per\ cent}}$. This translates to a Hubble constant $H_{0} = 71.6_{-4.9}^{+3.8}~\mathrm{km~s^{-1}~Mpc^{-1}}$, assuming a flat ΛCDM cosmology with a uniform prior on Ωm in the range [0.05, 0.5]. This work is part of the H0 Lenses in COSMOGRAIL’s Wellspring (H0LiCOW) collaboration, and the full time-delay cosmography results from a total of six strongly lensed systems are presented in a companion paper (H0LiCOW XIII).

Rusu, Cristian E.↗

Generating approximate halo catalogues for blind challenges in precision cosmology

ABSTRACT We present a method for generating suites of dark matter halo catalogues with only a few N-body simulations, focusing on making small changes to the underlying cosmology of a simulation with high precision. In the context of blind challenges, this allows us to re-use a simulation by giving it a new cosmology after the original cosmology is revealed. Starting with full N-body realizations of an original cosmology and a target cosmology, we fit a transfer function that displaces haloes in the original so that the galaxy/HOD power spectrum matches that of the target cosmology. This measured transfer function can then be applied to a new realization of the original cosmology to create a new realization of the target cosmology. For a 1 per cent change in σ8, we achieve 0.1 per cent accuracy to $k = 1\, h\, \mathrm{Mpc}^{-1}$ in the real-space power spectrum; this degrades to 0.3 per cent when the transfer function is applied to a new realization. We achieve similar accuracy in the redshift-space monopole and quadrupole. In all cases, the result is better than the sample variance of our $1.1\, h^{-1}\, \mathrm{Gpc}$ simulation boxes.

79 ASTRONOMY AND ASTROPHYSICS↗

Blinded challenge for precision cosmology with large-scale structure: Results from effective field theory for the redshift-space galaxy power spectrum

An accurate theoretical template for the galaxy power spectrum is key for the success of ongoing and future spectroscopic surveys. We examine to what extent the effective field theory (EFT) of large-scale structure is able to provide such a template and correctly estimate cosmological parameters. To that end, we initiate a blinded challenge to infer cosmological parameters from the redshift-space power spectrum of high-resolution mock catalogs mimicking the BOSS galaxy sample but covering a 100 times larger cumulative volume. This gigantic simulation volume allows us to separate systematic bias due to theoretical modeling from the statistical error due to sample variance. The challenge is to measure three unknown input parameters used in the simulation: the Hubble constant, the matter density fraction, and the clustering amplitude. We present analyses done by two independent teams, who have fitted the mock simulation data generated by yet another independent group. This allows us to avoid any confirmation bias by analyzers and to pin down possible tuning of the specific EFT implementations. Both independent teams have recovered the true values of the input parameters within subpercent statistical errors corresponding to the total simulation volume.

79 ASTRONOMY AND ASTROPHYSICS↗

Active elastohydrodynamics of vesicles in narrow blind constrictions

Fluid-resistance limited transport of vesicles through narrow constrictions is a recurring theme in many biological and engineering applications. Inspired by the motor-driven movement of soft membrane-bound vesicles into closed neuronal dendritic spines, here we study this problem using a combination of passive three-dimensional simulations and a simplified semianalytical theory for the active transport of vesicles forced through constrictions by molecular motors. We show that the motion of these objects is characterized by two dimensionless quantities related to the geometry and to the strength of forcing relative to the vesicle elasticity. We use numerical simulations to characterize the transit time for a vesicle forced by fluid pressure through a constriction in a channel and find that relative to an open channel, transport into a blind end leads to the formation of a smaller forward-flowing lubrication layer that strongly impedes motion. When the fluid pressure forcing is complemented by forces due to molecular motors that are responsible for vesicle trafficking into dendritic spines, we find that the competition between motor forcing and fluid drag results in multistable dynamics reminiscent of the real system. Our study highlights the role of nonlocal hydrodynamic effects in determining the kinetics of vesicular transport in constricted geometries.

59 BASIC BIOLOGICAL SCIENCES↗

The seventh blind test of crystal structure prediction: structure ranking methods

A seventh blind test of crystal structure prediction has been organized by the Cambridge Crystallographic Data Centre. The results are presented in two parts, with this second part focusing on methods for ranking crystal structures in order of stability. The exercise involved standardized sets of structures seeded from a range of structure generation methods. Participants from 22 groups applied several periodic DFT-D methods, machine learned potentials, force fields derived from empirical data or quantum chemical calculations, and various combinations of the above. In addition, one non-energy-based scoring function was used. Results showed that periodic DFT-D methods overall agreed with experimental data within expected error margins, while one machine learned model, applying system-specific AIMnet potentials, agreed with experiment in many cases demonstrating promise as an efficient alternative to DFT-based methods. For target XXXII, a consensus was reached across periodic DFT methods, with consistently high predicted energies of experimental forms relative to the global minimum (above 4 kJ mol −1 at both low and ambient temperatures) suggesting a more stable polymorph is likely not yet observed. The calculation of free energies at ambient temperatures offered improvement of predictions only in some cases (for targets XXVII and XXXI). Several avenues for future research have been suggested, highlighting the need for greater efficiency considering the vast amounts of resources utilized in many cases.

Chemistry↗

Evaluating Recursive Blind Forecast Against API and Baseline: A Puerto Rican Case Study on Solar Irradiance for Normal and Extreme Weather

This paper leverages ongoing work in a community microgrid in Adjuntas, Puerto Rico to forecast global horizontal irradiance (GHI) and compare performance in normal and extreme weather. Given a positive correlation of 0.98 between GHI and PV power, forecasting GHI can be an effective, indirect forecast of photovoltaic (PV) power, especially in microgrids where the end-users, owners, operators, or other stakeholders are reluctant to share data for training or validation due to privacy and security concerns. A recursive one-shot (termed as "blind") forecast is, hence, formulated, wherein a gradient-boosted regression tree (GBR) is built to forecast GHI for a 7-day horizon in normal weather, and a 2-day horizon in extreme weather. To demonstrate its resilience, the architecture is trained on normal and hurricane weather GHI from 2002-2022. It is generalized on February 9-16, 2023, and on the landfall of Hurricane Nicole (Nov 4-5, 2022), respectively. Forecasts from GBR are compared against that from a satellite-based API resource and three baselines: persistence, averaging, and exponential smoothing. Results show GBR and persistence outperform sophisticated API in both types of weather for this case study.

Sundararajan, Aditya↗

Spread Spectrum Symbol Detection With Blind Interference Suppression in FBMC-SS

Recent works have demonstrated Filter Bank Multicarrier Spread Spectrum (FBMC-SS) to be a robust communication scheme in the presence of high-power interferers. Existing FBMC-SS symbol detector designs based on analysis filter banks (AFB) suggest using an optimal combining scheme to suppress the interferers, necessitating some noise/interference power estimation method. In this paper, we introduce a symbol detector with blind interference suppression by extending a recently developed packet detection method. We then provide an analysis to show that the existing AFB-based symbol detector and the one proposed in this paper are equivalent in typical usage scenarios. A fully-fledged receiver design is proposed utilizing this symbol detector, with specifics presented for estimation of the channel impulse response and carrier frequency offset (CFO). We also outline a method of iterating upon the channel and CFO estimations to improve the quality of both parameters. Moreover, a modification to allow improved performance of the symbol detector at high SNR is provided. Finally, simulated performance results are presented to corroborate these findings and demonstrate the efficiency of this receiver design.

99 GENERAL AND MISCELLANEOUS↗

Non-Blind Deblurring for Fluorescence: A Deformable Latent Space Approach with Kernel Parameterization

We report N\non-blind deblurring (NBD) is a modeling method of the image deblurring problem in computer vision, where the blurring kernel is known or can be externally estimated. In this paper, we attempt to solve a parametric NBD problem, inspired by the simultaneous acquisition of ptychography and fluorescent imaging (FI). Ptychography is an imaging method that favors larger probes, i.e. convolutional kernels, while FI relies on a small probe for high resolution. Also, the kernel can be solved during ptychographic reconstruction. With Ptycho-FI using the same larger kernel, we can perform NBD on the blurred fluorescent images to achieve high-resolution FI, and thus speed up the experiments. To this end, we design a deep latent space deformation network that is directly parameterized by the kernel. The network consists of three components: encoder, deformer, and decoder, where the deformer is specifically meant to rectify the latent space representations of blurred images to a standard latent space, regardless of the kernel. The deformation network is trained with a two-stage training scheme. We conduct extensive experiments to confirm that our parametric model can adapt to drastically different blurring kernels and perform robust deblurring.

77 NANOSCIENCE AND NANOTECHNOLOGY↗

Split‐dose 4‐L polyethylene glycol regimen for patients with previous colorectal surgery in bowel preparation before colonoscopy: A randomized, controlled, single‐blind study

OBJECTIVE We aimed to investigate the efficacy of a split‐dose 4‐L polyethylene glycol (PEG) regimen for the quality of bowel preparation in Asian patients with previous colorectal surgery for colorectal cancer (CRC). METHODS This was a prospective, single‐center, randomized controlled, endoscopist‐blinded study. Patients with previous colorectal surgery for CRC were randomly allocated to a routine, morning‐only 2‐L PEG (2‐MO) group or a split‐dose 4‐L PEG (4‐SD) group. The primary outcome was a successful bowel preparation rate. Secondary outcomes were polyp detection rate (PDR), adenoma detection rate (ADR), patient compliance, satisfaction, tolerance, willingness to repeat the preparation and difficulty of the bowel preparation process. RESULTS In total, 187 patients were included (93 in the 2‐MO group, 94 in the 4‐SD group) in this study. The rate of successful bowel preparation in the 4‐SD group was higher than in the 2‐MO group (89.4% vs 66.7%, P < 0.001) in an intention‐to‐treat analysis according to the Aronchick score. Patients’ satisfaction with the bowel preparation process in the 4‐SD group was superior to that in the 2‐MO group (93.4% vs 82.2%, P = 0.021). No significant differences were detected in PDR, ADR, patient compliance, tolerance, willingness to repeat the preparation or difficulty of the bowel preparation process. CONCLUSIONS The 4‐SD PEG regimen was superior to a routine, morning‐only 2‐L PEG preparation for bowel preparation in an Asian population with previous colorectal surgery.

Liu, Zhu↗

A MUSE source-blind survey for emission from the circumgalactic medium

The recent detection of optical emission lines from the circumgalactic medium (CGM) in combined, large samples of low-redshift, normal galaxy spectra hints at the potential to map the cool (∼10 4 kelvin) CGM in individual, representative galaxies. Using archival data from a forefront instrument (MUSE) on the VLT, we present a source-blind, wide-redshift-range (z∼ 0 to 5) narrowband imaging survey for CGM emission. Our detected, resolved emission line sources are cataloged and include a 30-kiloparsec-wide Hα source likely tracing the CGM of a low-mass galaxy (stellar mass ∼ 10 8.78±0.42 solar mass) atz= 0.1723, a 60-kiloparsec-wide Ly α structure associated with a galaxy atz= 3.9076, and a 130-kiloparsec (∼r vir )–wide [O II] feature revealing an interaction between a galaxy pair atz= 1.2480. The Hα velocity field for the low-mass galaxy suggests that the CGM is more chaotic or turbulent than the galaxy disk, while that for the interacting galaxies shows large-scale (∼50 kiloparsec) coherent motions.

Science & Technology - Other Topics↗

Energy Conservation in Distributed Interference as a Guarantee for Detecting a Detector Blinding Attack in Quantum Cryptography

An avalanche single-photon detector blinding attack is one of the methods for quantum hacking of quantum key distribution (QKD) systems. The attack was experimentally demonstrated for both phase- and polarization-encoded QKD systems. During this attack, an eavesdropper knows the entire key, does not produce errors and саnnot be detected. However, the phase encoding has neglected some significant features of the photocount statistics in the receiving party. It is shown in the paper at the level of fundamental principles that this attack changes the photocount statistics and leads to the detection of an eavesdropper. Expressions for the secret key length are obtained for this attack. This does not require any changes in the design and control electronics of the phase-encoded QKD system, and only changes in processing the results of registration of quantum states are sufficient. At the same time, the secret key vulnerability and compromise in polarization-encoded QKD systems is an existing fact rather than a potential menace.

71 CLASSICAL AND QUANTUM MECHANICS, GENERAL PHYSIC↗

Method of Blind Detection of Ultrawideband Chaotic Radio Pulses on the Background of Interpulse Interference

The problem of blind detection of ultrawideband (UWB) microwave chaotic radio pulses transmitted via a multipath propagation channel has been considered. Based on the results of measurements of the UWB chaotic radio pulse propagation in a real wireless channel, a method of their detection not subject to the influence of interpulse interference is proposed.

71 CLASSICAL AND QUANTUM MECHANICS, GENERAL PHYSIC↗

Boosting of HIV envelope CD4 binding site antibodies with long variable heavy third complementarity determining region in the randomized double blind RV305 HIV-1 vaccine trial

The canary pox vector and gp120 vaccine (ALVAC-HIV and AIDSVAX B/E gp120) in the RV144 HIV-1 vaccine trial conferred an estimated 31% vaccine efficacy. Although the vaccine Env AE.A244 gp120 is antigenic for the unmutated common ancestor of V1V2 broadly neutralizing antibody (bnAbs), no plasma bnAb activity was induced. The RV305 (NCT01435135) HIV-1 clinical trial was a placebo-controlled randomized double-blinded study that assessed the safety and efficacy of vaccine boosting on B cell repertoires. HIV-1-uninfected RV144 vaccine recipients were reimmunized 6–8 years later with AIDSVAX B/E gp120 alone, ALVAC-HIV alone, or a combination of ALVAC-HIV and AIDSVAX B/E gp120 in the RV305 trial. Env-specific post-RV144 and RV305 boost memory B cell VH mutation frequencies increased from 2.9% post-RV144 to 6.7% post-RV305. The vaccine was well tolerated with no adverse events reports. While post-boost plasma did not have bnAb activity, the vaccine boosts expanded a pool of envelope CD4 binding site (bs)-reactive memory B cells with long third heavy chain complementarity determining regions (HCDR3) whose germline precursors and affinity matured B cell clonal lineage members neutralized the HIV-1 CRF01 AE tier 2 (difficult to neutralize) primary isolate, CNE8. Electron microscopy of two of these antibodies bound with near-native gp140 trimers showed that they recognized an open conformation of the Env trimer. Although late boosting of RV144 vaccinees expanded a novel pool of neutralizing B cell clonal lineages, we hypothesize that boosts with stably closed trimers would be necessary to elicit antibodies with greater breadth of tier 2 HIV-1 strains.

60 APPLIED LIFE SCIENCES↗

Novel Coupled Thermochronometric and Geochemical Investigation of Blind Geothermal Resources in Fault-Controlled Dilational Corners

Geothermal plays in extensional and transtensional tectonic environments have long been a major target in the exploration of geothermal resources and the Dixie Valley area has served as a classic natural laboratory for this type of geothermal plays. In recent years, the interactions between normal faults and strike-slip faults, acting either as strain relay zones have attracted significant interest in geothermal exploration as they commonly result in fault-controlled dilational corners with enhanced fracture permeability and thus have the potential to host blind geothermal prospects. Structural ambiguity, complications in fault linkage, etc. often make the selection for geothermal exploration drilling targets complicated and risky. Though simplistic, the three main ingredients of a viable utility-grade geothermal resource are heat, fluids, and permeability. Our new geological mapping and fault kinematic analysis derived a structural model suggest a two-stage structural evolution with (a) middle Miocene N -S trending normal faults (faults cutting across the modern range), - and tiling Olio-Miocene volcanic and sedimentary sequences (similar in style to East Range and S Stillwater Range). NE-trending range-front normal faulting initiated during the Pliocene and are both truncating N-S trending normal faults and reactivating some former normal faults in a right-lateral fashion. Thus the two main fundamental differences to previous structural models are (1) N-S trending faults are pre-existing middle Miocene normal faults and (2) these faults are reactivated in a right-later fashion (NOT left-lateral) and kinematically linked to the younger NE-trending range-bounding normal faults (Pliocene in age). More importantly, this study provides the first constraints on transient fluid flow through the novel application of apatite (U-Th)/He (AHe) and 4 He/ 3 He thermochronometry in the geothermally active Dixie Valley area in Nevada.

(U-Th)/He↗

Prototype Demonstration of Gamma- Blind Tensioned Metastable Fluid Neutron/Multiplicity/Alpha Detector – Real Time Methods for Advanced Fuel Cycle Applications

The content of this report summarizes a multi-year effort to develop prototype detection equipment using the Tensioned Metastable Fluid Detector (TMFD) technology developed by Taleyarkhan [1]. The context of this development effort was to create new methods for evaluating and developing advanced methods for safeguarding nuclear materials along with instrumentation in various stages of the fuel cycle, especially in material balance areas (MBAs) and during reprocessing of used nuclear fuel. One of the challenges related to the implementation of any type of MBA and/or reprocessing technology (e.g., PUREX or UREX) is the real-time quantification and control of the transuranic (TRU) isotopes as they move through the process. Monitoring of higher actinides from their neutron emission (including multiplicity) and alpha signatures during transit in MBAs and in aqueous separations is a critical research area. By providing on-line real-time materials accountability, diversion of the materials becomes much more difficult. The Tensioned Metastable Fluid Detector (TMFD) is a transformational technology that is uniquely capable of both alpha and neutron spectroscopy while being “blind” to the intense gamma field that typically accompanies used fuel – simultaneously with the ability to provide multiplicity information as well [1-3]. The TMFD technology was proven (lab-scale) as part of a 2008 NERI-C program [1-7]. The bulk of this report describes the advancements and demonstrations made in TMFD technology. One final point to present before turning to the TMFD demonstrations is the context for discussing real-time monitoring of SNM. It is useful to review the spectrum of isotopes generated within nuclear fuel during reactor operations. Used nuclear fuel (UNF) from a light water reactor (LWR) contains fission products as well as TRU elements formed through neutron absorption/decay chains. The majority of the fission products are gamma and beta emitters and they represent the more significant hazards from a radiation protection standpoint. However, alpha and neutron emitting uranium and TRU elements represent the more significant safeguards and security concerns. Table 1.1 presents a representative PWR inventory of the uranium and actinide isotopes present in a used fuel assembly. The uranium and actinide isotopes (chiefly the Pu, Am and Cm elements) are all emitters of alpha particles and some of them release significant quantities of neutrons through spontaneous fissions

46 INSTRUMENTATION RELATED TO NUCLEAR SCIENCE AND ↗

Blind Intercomparison of Nuclear Accident Dosimetry using the Flattop Reactor at NCERC

The purpose of this exercise was to continue United States, United Kingdom, and France collaborative activities performing Nuclear Accident Dosimetry intercomparison. IER 148 was the inaugural intercomparison exercise using the Godiva reactor at the DAF. In contrast to IER 148, in the current exercise participants were “blind” to the known doses during the exercise, to simulate the dosimetry response to a real criticality incident. This document is the Final Exercise (CED-x) Report for IER-253, “International Intercomparison Exercise for Nuclear Accident Dosimetry at the DAF Using Flattop.” The report describes the structure and results of the exercise consisting of two irradiations. The details of all dosimetry elements and their placement in proximity to Flattop on support stands or phantoms was unknown to participating laboratories. The participating laboratories in this report are deidentified and the report summarizes participant results from the intercomparison. The exercise occurred during the week of May 21, 2018.

42 ENGINEERING↗

Highly Efficient Solar-Blind Single Photon Detectors

Photodetectors sensitive to the ultra-violet spectrum were demonstrated using an AlGaN high electron mobility transistor with an GaN nanodot optical floating gate. Peak responsivity of 2 x 10 9 A/W was achieved with a gain-bandwidth product > 1 GHz at a cut-on energy of 4.10 eV. Similar devices exhibited visible-blind rejection ratios > 10 6 . The photodetection mechanism for $β$-Ga 2 O 3 was also investigated. It was concluded that Schottky barrier lowering by self-trapped holes enables photodetector gain.

46 INSTRUMENTATION RELATED TO NUCLEAR SCIENCE AND ↗