Biochemical and structural analyses reveal that the tumor suppressor neurofibromin (NF1) forms a high-affinity dimer
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Sherekar, Mukul (ORCID:0000000236389420)↗
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Results for “biochemicals”
Search indexed NASA NTRS and DOE OSTI research on propulsion, heat transfer, battery materials and energy systems. Follow report and document links to the original sources.
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The Biochemical Impact of Extracting an Embedded Adenylate Kinase Domain Using Circular Permutation
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Biochemistry & Molecular Biology↗
Structural and Biochemical Insights into the Inhibition of Human Acetylcholinesterase by G-Series Ne
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McGuire, Jack R.↗
Structure-Guided Design of Potent Inhibitors of SARS-CoV-2 3CL Protease: Structural, Biochemical, an
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Dampalla, Chamandi S.↗
Structure-Guided Design of Potent Coronavirus Inhibitors with a 2-Pyrrolidone Scaffold: Biochemical, Crystallographic, and Virological Studies
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Pharmacology & Pharmacy↗
Biochemical and Structural Studies of the Carminomycin 4- O -Methyltransferase DnrK
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Pharmacology & Pharmacy↗
Structural and Biochemical Characterization of Fusobacterium nucleatum Enoyl-ACP Reductase II (FabK) Reveals the Basis for Bacterial Species-Specific Inhibition
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Avad, Kristiana [Department of Pharmaceutical Scie↗
Structural and Biochemical Studies of a Biocatalyst for the Enzymatic Production of Wax Esters
Abstract not provided
Petronikolou, Nektaria↗
Structure-Guided Biochemical Analysis of Quorum Signal Synthase Specificities
Abstract not provided
Dong, Shi-Hui↗
Structural, Biochemical, and Bioinformatic Basis for Identifying Radical SAM Cyclopropyl Synthases
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Biochemistry & Molecular Biology↗
Quantum Mechanical Methods Predict Accurate Thermodynamics of Biochemical Reactions
Not Available
37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CH↗
Structural and Biochemical Characterization of the Flavin-Dependent Siderophore-Interacting Protein
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Valentino, Hannah↗
Structural and biochemical characterization of the exopolysaccharide deacetylase Agd3 required for Aspergillus fumigatus biofilm formation
The exopolysaccharide galactosaminogalactan (GAG) is an important virulence factor of the fungal pathogen Aspergillus fumigatus. Deletion of a gene encoding a putative deacetylase, Agd3, leads to defects in GAG deacetylation, biofilm formation, and virulence. Here, we show that Agd3 deacetylates GAG in a metal-dependent manner, and is the founding member of carbohydrate esterase family CE18. The active site is formed by four catalytic motifs that are essential for activity. The structure of Agd3 includes an elongated substrate-binding cleft formed by a carbohydrate binding module (CBM) that is the founding member of CBM family 87. Agd3 homologues are encoded in previously unidentified putative bacterial exopolysaccharide biosynthetic operons and in other fungal genomes.
99 GENERAL AND MISCELLANEOUS↗
Biochemical and structural basis for differential inhibitor sensitivity of EGFR with distinct exon 1
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van Alderwerelt van Rosenburgh, Iris K.↗
Biochemical implementation of acceleration sensing and PIDA control
Not provided.
Mathematical & Computational Biology↗