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At least 127 records · Page 7

Accurate determination of production data of the non-standard positron emitter 86 Y via the 86 Sr(p,n)-reaction

In view of several significant discrepancies in the excitation function of the 86 Sr(p,n) 86g+xm Y reaction which is the method of choice for the production of the non-standard positron emitter 86 Y for theranostic application, we carried out a careful measurement of the cross sections of this reaction from its threshold up to 16.2 MeV at Forschungszentrum Jülich (FZJ) and from 14.3 to 24.5 MeV at LBNL. Thin samples of 96.4% enriched 86 SrCO 3 were prepared by sedimentation and, after irradiation with protons in a stacked-form, the induced radioactivity was measured by high-resolution γ -ray spectrometry. The projectile flux was determined by using the monitor reactions nat Cu(p,xn) 62,63,65 Zn and nat Ti(p,x) 48 V, and the calculated proton energy for each sample was verified by considering the ratios of two reaction products of different thresholds. Additionally, the experimental cross section data obtained agreed well with the results of a nuclear model calculation based on the code TALYS. From the cross section data, the integral yield of 86 Y was calculated. Over the optimum production energy range E p = 14 → 7 MeV the yield of 86 Y amounts to 291 MBq/μA for 1 h irradiation time. This value is appreciably lower than the previous literature values calculated from measured and evaluated excitation functions. It is, however, more compatible with the experimental yields of 86 Y obtained in clinical scale production runs. The levels of the isotopic impurities 87m Y, 87g Y, and 88 Y were also estimated and found to be <2% in sum.

38 RADIATION CHEMISTRY, RADIOCHEMISTRY, AND NUCLEA↗

Selected advances in the accelerator design of the Future Circular Electron-Positron Collider (FCC-ee)

In autumn 2023, the FCC Feasibility Study underwent a crucial “mid-term review”. We describe some accelerator performance risks for the proposed future circular electron-positron collider, FCC-ee, identified for, and during, the mid-term review. For the collider rings, these are the collective effects when running on the Z resonance – especially resistive wall, beam-beam, and electron cloud –, the beam lifetime, dynamic aperture, alignment tolerances, and beam-based alignment. For the booster, the primary concern is the vacuum system, with regard to impedance and effects of the residual gas. For the injector, the layout and the linac repetition rate are primary considerations. We discuss the various issues and report the planned mitigations.

43 PARTICLE ACCELERATORS↗

A High Intensity Spin-Polarized Electron Photogun to Drive a Polarized Positron Source

A photogun to generate a high-intensity, highly spin-polarized electron beam >90% with unprecedented charge lifetime in the kilocoulomb range is envisioned at JLab for a proposed Ce+BAF polarized positron beam source. The electron photogun is expected to provide a CW beam of >1 mA for a month without intervention. A limiting factor is ion-back bom-bardment on the strained-superlattice GaAs-photocathode which can be reduced by improving the photogun vacuum or biasing the anode. Additionally, increasing the laser spot size can help mitigate ion-induced damage. However, eventually the laser size becomes too large for the photogun electrode. An envisioned photogun design will incorporate larger electrodes to accommodate larger and off-center laser spot sizes. Compatible larger conical insulators which operate >300 kV for beam injection into a Beta~1 SRF booster are also necessary.

Hernandez Garcia, Carlos↗

Identifying Redox Orbitals and Defects in Lithium-Ion Cathodes with Compton Scattering and Positron Annihilation Spectroscopies: A Review

Reduction-oxidation (redox) reactions that transfer conduction electrons from the anode to the cathode are the fundamental processes responsible for generating power in Li-ion batteries. Electronic and microstructural features of the cathode material are controlled by the nature of the redox orbitals and how they respond to Li intercalation. Thus, redox orbitals play a key role in performance of the battery and its degradation with cycling. We unravel spectroscopic descriptors that can be used to gain an atomic-scale handle on the redox mechanisms underlying Li-ion batteries. Our focus is on X-ray Compton Scattering and Positron Annihilation spectroscopies and the related computational approaches for the purpose of identifying orbitals involved in electrochemical transformations in the cathode. This review provides insight into the workings of lithium-ion batteries and opens a pathway for rational design of next-generation battery materials.

Nokelainen, Johannes (ORCID:0000000328857850)↗

Systems and methods for point-of-care positron emission tomography

A positron emission tomography (PET) system is provided. The system includes a first detector panel including a first array of detectors, a second detector panel including a second array of detectors, said second detector panel being moveable relative to a point between the first detector panel and the second detector panel, a tracking system configured to detect a position of said second detector panel relative to the first detector panel while imaging a subject, a computing device in communication with the first detector panel, the second detector panel, and the tracking system, the computing device configured to receive coincidence data from the first and second detector panels, receive position data from the tracking system, wherein each coincidence datum of the received coincidence data is associated with a unique position datum of the received position data, and reconstruct a plurality of images based on the received coincidence data and the received position data.

Tai, Yuan-Chuan↗

Positron Emission Tomography Imaging of Functional Transforming Growth Factor β (TGFβ) Activity and Benefit of TGFβ Inhibition in Irradiated Intracranial Tumors

Transforming growth factor β (TGFβ) promotes cell survival by endorsing DNA damage repair and mediates an immunosuppressive tumor microenvironment. Thus, TGFβ activation in response to radiation therapy is potentially targetable because it opposes therapeutic control. Strategies to assess this potential in the clinic are needed.

62 RADIOLOGY AND NUCLEAR MEDICINE↗

Joint thrust and TMD resummation in electron-positron and electron-proton collisions

In this work, we present the framework for obtaining precise predictions for the transverse momentum of hadrons with respect to the thrust axis in e + e - collisions. This will enable a precise extraction of transverse momentum dependent (TMD) fragmentation functions from a recent measurement by the Belle Collaboration. Our analysis takes into account, for the first time, the nontrivial interplay between the hadron transverse momentum and the cut on the thrust event shape. To this end, we identify three different kinematic regions, derive the corresponding factorization theorems within Soft Collinear Effective Theory, and present all ingredients needed for the joint resummation of the transverse momentum and thrust spectrum at NNLL accuracy. One kinematic region can give rise to non-global logarithms (NGLs), and we describe how to include the leading NGLs. We also discuss alternative measurements in e + e - collisions that can be used to access the TMD fragmentation function. Finally, by using crossing symmetry, we obtain a new way to constrain TMD parton distributions, by measuring the displacement of the thrust axis in ep collisions.

72 PHYSICS OF ELEMENTARY PARTICLES AND FIELDS↗