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At least 127 records · Page 7

All sources NASA NTRS DOE OSTI

DOE OSTI2024

Development and cross‐validation of a circumference‐based predictive equation to estimate body fat in an active population

Abstract Objective The U.S. Army uses sex‐specific circumference‐based prediction equations to estimate percent body fat (%BF) to evaluate adherence to body composition standards. The equations are periodically evaluated to ensure that they continue to accurately assess %BF in a diverse population. The objective of this study was to develop and validate alternative field expedient equations that may improve upon the current Army Regulation (AR) body fat (%BF) equations. Methods Body size and composition were evaluated in a representatively sampled cohort of 1904 active‐duty Soldiers (1261 Males, 643 Females), using dual‐energy X‐ray absorptiometry (%BF DXA ), and circumferences obtained with 3D imaging and manual measurements. Sex stratified linear prediction equations for %BF were constructed using internal cross validation with %BF DXA as the criterion measure. Prediction equations were evaluated for accuracy and precision using root mean squared error, bias, and intraclass correlations. Equations were externally validated in a convenient sample of 1073 Soldiers. Results Three new equations were developed using one to three circumference sites. The predictive values of waist, abdomen, hip circumference, weight and height were evaluated. Changing from a 3‐site model to a 1‐site model had minimal impact on measurements of model accuracy and performance. Male‐specific equations demonstrated larger gains in accuracy, whereas female‐specific equations resulted in minor improvements in accuracy compared to existing AR equations. Equations performed similarly in the second external validation cohort. Conclusions The equations developed improved upon the current AR equation while demonstrating robust and consistent results within an external population. The 1‐site waist circumference‐based equation utilized the abdominal measurement, which aligns with associated obesity related health outcomes. This could be used to identify individuals at risk for negative health outcomes for earlier intervention.

Taylor, Kathryn M.↗

DOE OSTI2020

Soft de Sitter Effective Theory

Calculating the quantum evolution of a de Sitter universe on superhorizon scales is notoriously difficult. To address this challenge, we introduce the Soft de Sitter Effective Theory (SdSET). This framework holds for superhorizon modes whose comoving momentum is far below the UV scale, which is set by the inverse comoving horizon. The SdSET is formulated using the same approach that yields the Heavy Quark Effective Theory. The degrees of freedom that capture the long wavelength dynamics are identified with the growing and decaying solutions to the equations of motion. The operator expansion is organized using a power counting scheme, and loops can be regulated while respecting the low energy symmetries. For massive quantum fields in a fixed de Sitter background, power counting implies that all interactions beyond the horizon are irrelevant. Alternatively, if the fields are very light, the leading interactions are at most marginal, and resumming the associated logarithms using (dynamical) renormalization group techniques yields the evolution equation for canonical stochastic inflation. The SdSET is also applicable to models where gravity is dynamical, including inflation. In this case, diffeomorphism invariance ensures that all interactions are irrelevant, trivially implying the all-orders conservation of adiabatic density fluctuations and gravitational waves. We briefly touch on the application to slow-roll eternal inflation by identifying novel relevant operators. This work serves to demystify many aspects of perturbation theory outside the horizon, and has a variety of applications to problems of cosmological interest.

72 PHYSICS OF ELEMENTARY PARTICLES AND FIELDS↗

DOE OSTI2022

A radioisotope - enabled reactive transport model for deep vadose zone carbon

In mountainous regions, which constitute the principle source of recharge to major rivers and regional aquifers, infiltration occurs through fractured, partially saturated, weathered bedrock that acts as a boundary layer between saturated aquifers and surface soil. Commonly this deep vadose zone (DVZ) is many meters thick, and yet its role in regulating the generation, retention and mobility of reactive solutes, including nutrients, contaminants and weathering products, is largely unknown. In particular, many of the key reactions that drive the formation of the weathered DVZ and the quality of water moving through it are redox processes, regulated by the availability of organic carbon and oxygen below the soil layer. The role of the DVZ is thus also poorly constrained in the context of carbon stocks and mobility, particularly in lithologies that are naturally high in organic carbon, such as shales. The overarching hypothesis of this study is that upland regions developed in geologic settings with abundant petrogenic carbon store and actively cycle carbon in the weathered DVZ below the soil and above the water table at rates that are significant and currently unconstrained. In order to quantify this cycling, the current study combines novel instrumentation techniques allowing new direct sampling of DVZ systems with advanced numerical reactive transport simulations of carbon transport and transformation. Critically, these simulations will explicitly treat the three isotopes of carbon (the abundant 12C, the stable rare 13C and the radioactive 14C) in a unified framework, thus clearly parsing between the contributions of modern surface derived carbon and lithologic carbon sources in integrated measurements of fluid and gas phase fluxes. This novel model capability will be applied to test the role of DVZ carbon cycling as a regulator of water quality and geological weathering in two complementary field sites both located in organic carbon rich shale lithologies. The first is the Eel River Critical Zone Observatory (ERCZO) in Mendocino County, California, and the second is the Lawrence Berkeley National Laboratory Watershed Function Scientific Focus Area (SFA) in the East River watershed, near Crested Butte, Colorado. At the ERCZO, a novel vadose zone monitoring system has been installed in a 20 m thick, partially saturated, weathered shale hillslope, and preliminary data already indicate substantial CO2 flux generated many meters below the soil surface. At the SFA field site, an instrumented hillslope transect indicates a more complex multi-dimensional fluid and solute transport regime, which will serve as a key test of the calibrated models. Collectively, this project will advance understanding of the cycling of carbon belowground and in relation to transport pathways across the poorly constrained DVZ characteristic of primary water recharge areas. The key product of this work will be enhanced isotope simulation capabilities that are robust and publicly available for application across a broad diversity of systems.

58 GEOSCIENCES↗

NASA NTRS1978

Body mass, composition, and food intake in rabbits during altered acceleration fields

Mature male Polish rabbits were subjected to varying gravitational fields in an animal centrifuge in order to evaluate the effects of acceleration and deacceleration on body mass, body composition, and food intake. The acceleration field intensity was increased by 0.25-G increments to a maximum of 2.5 G at intervals which permitted physiological adaptation at each field. Control animals of the same age were maintained at earth gravity under identical conditions of constant-light environment at a room temperature of 23 + or - 5 C. It is shown that increasing the acceleration-field intensity leads to a decrease in body mass. The regulated nature of this decreased body mass is tested by the response to an additional three-day fasting of animals adapted physiologically to 2.5 G. Ad libitum food intake per kg body mass per day tends to increase in chronically accelerated animals above 1.75 G. Increase in water content in centrifuged animals after physiological adaptation to 2.5 G is the result of decreasing body fat. Body mass and food intake returned to the precentrifuged levels of control animals within six weeks after cessation of centrifugation.

Katovich, M. J.↗

NASA NTRS2018

Experimental Evaluation of BLI Propulsion: The Boundary Layer Ingesting Inlet/Distortion-Tolerant Fan Solution

NASA has successfully developed a new testbed configuration for experimentally evaluating embedded boundary layer ingesting aircraft propulsors in its 8'x6' Supersonic Wind Tunnel. This testbed meets the challenges of providing the necessary freestream flow Mach conditions and desired range and distribution of boundary layer thickness for embedded aircraft propulsion systems. The testbed consists of a 48ft long raised wind tunnel floor aircraft surface simulator and a boundary layer regulation system to produce propulsion-local aircraft aerodynamic flow fields. This durable special test equipment is designed to be installed in the wind tunnel's transonic test section and is capable of evaluating a wide range of subcritical and supercritical airframe-propulsion integration configurations for subsonic cruise aircraft. The wind tunnel and testbed are well suited for meeting the test requirements of these propulsors in the most cost efficient way and has been aerodynamically calibrated and proven through tests of a first-of-its-kind boundary layer ingesting propulsor.

Arend, David J.↗

NASA NTRSDate not supplied

TPSAS-NF1676L-18199-DND

Commercial aircraft in the United States are forbidden from flying faster than the speed of sound (approximately 660 miles per hour at an altitude of 35,000 feet) because of the community annoyance caused by conventional sonic booms. A sonic boom is the sound of a shock wave caused by an object traveling supersonically, or faster than the speed of sound. NASA is developing technology to reduce sonic boom noise so commercial passengers can fly supersonically over land. The technology is driven by advances in aircraft shaping techniques. If a noise-based standard were adopted for overland supersonic flight, it would greatly reduce transit times as well as create new jobs in the aerospace manufacturing industry. NASA is currently funding the design of a shaped supersonic aircraft capable of demonstrating quiet sonic booms to communities and policy-makers. Concurrently, efforts are underway to develop a suitable noise metric for regulating sonic boom noise. This presentation will highlight laboratory and field studies conducted to develop the noise metric.

Jonathan Rathsam↗

NASA NTRSDate not supplied

Study of Advanced Occupant Models to Quantify Injury Risk for eVTOL Vehicles

Urban transportation is currently evolving from traditional ground-based vehicles (cars, taxis, and buses) to include air-based electric vertical take-off and landing (eVTOL) vehicles which can be utilized for on-demand transportation, cargo transport, and emergency services. These new eVTOL vehicles are designed to be small, lightweight, and able to operate autonomously without user intervention. Safety is a big part of eventual eVTOL adoption, however gaps in the consideration of safety features exist. Anthropomorphic test devices (ATDs) are used in aerospace crashworthiness standards to quantify occupant injury risk and develop improved safety designs for emergency landing situations, but the ATDs currently used in aircraft certification requirements were developed many decades ago. Developments have occurred over the years involving ATD technology, which includes a host of newer and more biofidelic ATDs such as the Test Device for Human Occupant Restraint (THOR). Increased computing power has also allowed for detailed computational human body models (HBMs) to be created, such as the Global Human Body Model Consortium (GHBMC). This study aims to assess the capability of both HBMs and new ATD designs to identify injury mechanisms within eVTOL relevant emergency landing conditions. Finite element (FE) analysis was used to expand upon full-scale and seat level impact testing conducted by researchers at the National Aeronautics and Space Administration (NASA) to look at effects of occupant model configurations on prediction of injury. The GHBMC HBM and THOR ATD models were simulated in the seat level test conditions to characterize differences between these advanced assessment tools and traditional ATDs in the isolated seat loading environment. Results identified key differences in the responses from each of the models utilized and compared their impact response in head, neck, and spinal injury metrics. The THOR model identified potential risks for head injuries due to head impacts on the seat, however it predicted lower spinal loads than the other occupant surrogates. The GHBMC showed distinctly different biomechanical responses compared to the ATD. The GHBMC model is much more deformable than the ATDs and it exhibited higher distribution of forces and increased sensitivity to the duration of acceleration pulses. Both models incorporated into this study identified key mechanisms for injury that should be considered for passenger safety in the development of these novel aircraft. In addition, this study demonstrated the value of FE modeling for running a variety of complex human surrogates to identify potential injury mechanisms for consideration in regulation and development of new aircraft. Continued research in this field to improve validation these models will only lead to safer aircraft and more comprehensive safety measures.

Crashworthiness↗

NASA NTRSDate not supplied

Study of Advanced Occupant Models to Quantify Injury Risk for eVTOL Vehicles

Crashworthiness↗

NASA NTRS1977

Photovoltaic system test facility electromagnetic interference measurements

Field strength measurements on a single row of panels indicates that the operational mode of the array as configured presents no radiated EMI problems. Only one relatively significant frequency band near 200 kHz showed any degree of intensity (9 muV/m including a background level of 5 muV/m). The level was measured very near the array (at 20 ft distance) while Federal Communications Commission (FCC) regulations limit spurious emissions to 15 muV/m at 1,000 ft. No field strength readings could be obtained even at 35 ft distant.

Johnson, J. A.↗

DOE OSTI2026

Artificial Soiling Replication of Field Losses on Commercial Photovoltaic Modules

Here, this study demonstrates the capabilities of an indoor artificial soiling approach developed to closely replicate the natural, cyclic soil accumulation processes in the field-dust suspension, deposition, and sedimentation/cementation-for a subtropical climate. In this work, a near-field environment is replicated in an artificial soiling cubic chamber through controlled regulation of humidity, temperature, dust type, and dust concentration, based on site-specific historical climate data. Two different models (MA and MB) of full-size commercial photovoltaic modules from a single manufacturer, installed side by side in the mid-Atlantic United States, were retrieved and subjected to artificial soiling experiments and various characterization measurements, including short-circuit current, colorimetry, reflectance, X-ray fluorescence, laser diffraction, and optical microscopy. Both in the field and in our improved field-representative artificial soiling tests, the MA model experienced roughly twice the soiling loss as the MB model. To closely replicate the field soiling losses for a site-specific climate, it is critical to include: 1) The use of field-collected dust with identical dust chemistry and particle distribution instead of standardized ISO 12103 Arizona Road dusts, 2) the use of only a small amount of field-collected dust inside the chamber during the deposition process (e.g., 0.15 g), and 3) the preconditioning of the surface coating for the partial/full dose of UV stress as experienced in the field during sunlight exposure and the abrasion as experienced in the field during regular module cleaning activities, if/as needed. The field-representative artificial soiling method developed here could potentially be adopted for rank ordering of various antisoiling coatings developed by researchers and industry stakeholders.

14 SOLAR ENERGY↗

NASA NTRS1990

The effect of hyperdynamic fields on the oxidative metabolism of the paraventricular nucleus

An important issue in space biology and medicine is understanding the effect of gravitational changes on the mechanisms that regulate fluid homeostasis. The results of this study show that, following 7-d exposure to a 2 G or 3 G hyperdynamic field, rats exhibited a linear increase in the cytochrome oxidase staining of neurons in the paraventricular nucleus (PVN). The elevated oxidative metabolism in the PVN suggests that there was an increase in the manufacturing and release of vasopressin into the plasma in response to a perceived hypovolemic condition caused by increased hydrostatic pressure and redistribution of fluid to the periphery. Since vasopressin also has widespread cardiovascular effects, it will be important to understand the relationship between vasopressin and altered gravitational fields.

Murakami, Dean M.↗

NASA NTRS1998

The Design and Development of the SMEX-Lite Power System

This paper describes the design and development of a 250W orbit average electrical power system electronic Power Node and software for use in Low Earth Orbit missions. The mass of the Power Node is 3.6 Kg (8 lb.). The dimensions of the Power Node are 30cm x 26cm x 7.9cm (11 in. x 10.25 in x 3.1 in.) The design was realized using software, Field Programmable Gate Array (FPGA) digital logic and surface mount technology. The design is generic enough to reduce the non-recurring engineering for different mission configurations. The Power Node charges one to five, low cost, 22-cell 4 AH D-cell battery packs independently. The battery charging algorithms are executed in the power software to reduce the mass and size of the power electronic. The Power Node implements a peak-power tracking algorithm using an innovative hardware/software approach. The power software task is hosted on the spacecraft processor. The power software task generates a MIL-STD-1553 command packet to update the Power Node control settings. The settings for the battery voltage and current limits, as well as minimum solar array voltage used to implement peak power tracking are contained in this packet. Several advanced topologies are used in the Power Node. These include synchronous rectification in the bus regulators, average current control in the battery chargers and quasi-resonant converters for the Field Effect Transistor (FET) transistor drive electronics. Lastly, the main bus regulator uses a feed-forward topology with the PWM implemented in an FPGA.

Rakow, Glenn P.↗

DOE OSTI2021

Glioblastoma cell migration is directed by electrical signals

Electric field (EF) directed cell migration (electrotaxis) is known to occur in glioblastoma multiforme (GBM) and neural stem cells, with key signalling pathways frequently dysregulated in GBM. One such pathway is EGFR/PI3K/Akt, which is down-regulated by peroxisome proliferator activated receptor gamma (PPARγ) agonists. We investigated the effect of electric fields on primary differentiated and glioma stem cell (GSCs) migration, finding opposing preferences for anodal and cathodal migration, respectively. We next sought to determine whether chemically disrupting Akt through PTEN upregulation with the PPARγ agonist, pioglitazone, would modulate electrotaxis of these cells. We found that directed cell migration was significantly inhibited with the addition of pioglitazone in both differentiated GBM and GSCs subtypes. Western blot analysis did not demonstrate any change in PPARγ expression with and without exposure to EF. In summary we demonstrate opposing EF responses in primary GBM differentiated cells and GSCs can be inhibited chemically by pioglitazone, implicating GBM EF modulation as a potential target in preventing tumour recurrence.

60 APPLIED LIFE SCIENCES↗

NASA NTRS1985

Influence of exposure to a prolonged hyperdynamic field on body temperature in the squirrel monkey

The effect of gravitational loading on the regulation of body temperature is examined. Five adult male squirrel monkeys were exposed to a 2-G environment twice for 48 hours, once beginning in the middle of their light cycle and the second time in the middle of their dark cycle. It is observed that a reduction in body temperature occurs during the light cycle phase and at night there is an insignificant change in body temperature. The rhythmic characteristics of the light and dark cycles are analyzed. The data reveal that the body temperature in animals at 2 G is influenced more during the active phase of the animals 24-hour cycle.

Fuller, C. A.↗

DOE OSTI2021

Geometric quantum information structure in quantum fields and their lattice simulation

An upper limit to distillable entanglement between two disconnected regions of massless noninteracting scalar field theory has an exponential decay defined by a geometric decay constant. When regulated at short distances with a spatial lattice, this entanglement abruptly vanishes beyond a dimensionless separation, defining a negativity sphere. In two spatial dimensions, we determine this geometric decay constant between a pair of disks and the growth of the negativity sphere toward the continuum through a series of lattice calculations. Making the connection to quantum field theories in three-spatial dimensions, assuming such quantum information scales appear also in quantum chromodynamics (QCD), a new relative scale may be present in effective field theories describing the low-energy dynamics of nucleons and nuclei. Here, we highlight potential impacts of the distillable entanglement structure on effective field theories, lattice QCD calculations and future quantum simulations.

73 NUCLEAR PHYSICS AND RADIATION PHYSICS↗

DOE OSTI2020

High precision strike point control to support experiments in the DIII-D small angle slot divertor

Improvements in strike point control enabled tests with the new Small Angle Slot (SAS) divertor installed at DIII-D with precision as tight as ±1 mm, barring brief perturbations from ELMs. Aside from being narrower than previous baffle structures in DIII-D, simulations indicate that performance of the SAS divertor should be very sensitive to strike point position, making the improved strike point control essential for experiments with the SAS divertor. Improved control entails regulating more divertor geometry target locations than before and setting higher gain on the strike point target. This is achieved by tasking more poloidal field (PF) shaping coils with divertor topology control, fine tuning of the coil configuration and algorithm gains, and adding regulation of the power supply common rail. Here, the result is that although more variables are controlled, precision is better: high frequency jitter in the strike point position is lower on average compared to related discharges with standard divertor shape control.

70 PLASMA PHYSICS AND FUSION TECHNOLOGY↗

DOE OSTI2024

Machine Learning in Spill Regulation

Explore the source record for details and available documents.

72 PHYSICS OF ELEMENTARY PARTICLES AND FIELDS↗

DOE OSTI2021

A rich and bountiful harvest: Key discoveries in plant cell biology

Abstract The field of plant cell biology has a rich history of discovery, going back to Robert Hooke’s discovery of cells themselves. The development of microscopes and preparation techniques has allowed for the visualization of subcellular structures, and the use of protein biochemistry, genetics, and molecular biology has enabled the identification of proteins and mechanisms that regulate key cellular processes. In this review, seven senior plant cell biologists reflect on the development of this research field in the past decades, including the foundational contributions that their teams have made to our rich, current insights into cell biology. Topics covered include signaling and cell morphogenesis, membrane trafficking, cytokinesis, cytoskeletal regulation, and cell wall biology. In addition, these scientists illustrate the pathways to discovery in this exciting research field.

59 BASIC BIOLOGICAL SCIENCES↗