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At least 127 records · Page 7

Mechanosensitive Ion Channels in Bacteria: Functional Domains and Mechanisms of Gating

The past funding period was productive for the group. The progress in the mechanosensitive channel field was critically affected in the end of 1998 by the solution of the crystal structure of the mycobacterial homolog of MscL by our colleagues from Caltech. Having the structure of TbMscL in the closed state, we developed a detailed homology model of EcoMscL, and related the structural model with the wealth of functional phenomenology available for the E. coli version of the channel (EcoMscL). The biophysical properties of the open MscL helped to model the open conformation and infer the pathway for the entire gating transition. The following experiments provided strong support to the atomic model of the gating process, and allowed to make further predictions. The work has advanced our understanding of tension-driven conformational transitions in membrane-embedded mechanosensory proteins, determine major energetic contributions and set the stage for further exploration of the whole family of mechanosensitive channels. The results have been published in seven experimental and theoretical papers, with three other papers currently in press or in preparation.

Sukharev, Sergei↗

Studies of the Superconducting Transition in the Mo/Au-Bilayer Thin Films

At NASA Goddard, microcalorimeter arrays using superconducting transition edge sensor thermometers (TESs) are under development for high energy resolution X-ray astrophysics applications. We report on our studies of the superconducting transition in our Mo/Au-bilayer TES films including: low current measurements of the superconducting bilayer's resistance transition versus temperature on pixels with different normal metal absorber attachment designs and measured temperature scaling of the critical current and critical magnetic field.

Sadleir, John↗

An Investigation of Proposed Techniques for Quantifying Confidence in Assurance Arguments

The use of safety cases in certification raises the question of assurance argument sufficiency and the issue of confidence (or uncertainty) in the argument's claims. Some researchers propose to model confidence quantitatively and to calculate confidence in argument conclusions. We know of little evidence to suggest that any proposed technique would deliver trustworthy results when implemented by system safety practitioners. Proponents do not usually assess the efficacy of their techniques through controlled experiment or historical study. Instead, they present an illustrative example where the calculation delivers a plausible result. In this paper, we review current proposals, claims made about them, and evidence advanced in favor of them. We then show that proposed techniques can deliver implausible results in some cases. We conclude that quantitative confidence techniques require further validation before they should be recommended as part of the basis for deciding whether an assurance argument justifies fielding a critical system.

Graydon, Patrick J.↗

Development of Liquid Propulsion Systems Testbed at MSFC

As NASA, the Department of Defense and the aerospace industry in general strive to develop capabilities to explore near-Earth, Cis-lunar and deep space, the need to create more cost effective techniques of propulsion system design, manufacturing and test is imperative in the current budget constrained environment. The physics of space exploration have not changed, but the manner in which systems are developed and certified needs to change if there is going to be any hope of designing and building the high performance liquid propulsion systems necessary to deliver crew and cargo to the further reaches of space. To further the objective of developing these systems, the Marshall Space Flight Center is currently in the process of formulating a Liquid Propulsion Systems testbed, which will enable rapid integration of components to be tested and assessed for performance in integrated systems. The manifestation of this testbed is a breadboard engine configuration (BBE) with facility support for consumables and/or other components as needed. The goal of the facility is to test NASA developed elements, but can be used to test articles developed by other government agencies, industry or academia. Joint government/private partnership is likely the approach that will be required to enable efficient propulsion system development. MSFC has recently tested its own additively manufactured liquid hydrogen pump, injector, and valves in a BBE hot firing. It is rapidly building toward testing the pump and a new CH4 injector in the BBE configuration to demonstrate a 22,000 lbf, pump-fed LO2/LCH4 engine for the Mars lander or in-space transportation. The value of having this BBE testbed is that as components are developed they may be easily integrated in the testbed and tested. MSFC is striving to enhance its liquid propulsion system development capability. Rapid design, analysis, build and test will be critical to fielding the next high thrust rocket engine. With the maturity of the BBE testbed, MSFC propulsion engineering will bring forward a national capability that enables growth of both commercial and government interests.

Alexander, Reginald↗

The Light Microscopy Module A Facility Overview-History and Science

We will share a brief history and provide a science overview of the many accomplishments of the Light Microscopy Module (LMM), a microscope that has been operating in the microgravity environment of the International Space Station (ISS) since 2010. It will be removed in October 2021. It was initially outfitted for the Constrained Vapor Bubble – Wickless Heat Pipe experiment. It was later reconfigured and upgraded many times to support a broad portfolio of Physical science and Biological experiments including: Complex Fluids, Colloids, Macro-Molecular Biophysics, Protein Crystals, and Plant Biology. The LMM has enabled many significant studies and discoveries and has seen its fair share of pleasant surprises. These include recording order arising out of disorder, e.g., systems of colloids that were glasses on Earth crystallizing to form large defect-free crystals, nematic ordering of elliptical colloids, and colloidal-polymer systems crystallizing. The LMM science teams have also seen how to improve product stabilizers once the effects of sedimentation on Earth were removed; they were able to see which tagged genes express in plants when gravity is removed, telling them which genes are essential for growing plants in space; they’ve tested protein crystal growth models; checked models for creating bijel electrodes that turn batteries into fast-charging supercapacitors; tested many forms of colloidal self-assembly: including those using depletion attraction, magnetic fields, and critical Casimir forces; they’ve observed explosive bubble nucleation in a wickless heat pipe, and much more. This work has been supported by the NASA Biological and Physical Sciences (BPS) Division and the ISS Program Office, Johnson Space Center Code OZ and Code OB, the Center for the Advancement of Science in Space (CASIS) / ISS National Lab, EPSCoR, and ISS international partners from ESA – the Netherlands and Italy, CSA, JAXA and S. Korea, and by Space Act Agreements with Procter and Gamble (P&G).

Colloids↗

Flux creep in Bi2Sr2CaCu2O8(sub +x) single crystals

The results of a magnetic study on a Bi2Sr2CaCu2O(8+x) single crystal are reported. Low field susceptibility (dc and ac), magnetization cycles and time dependent measurements were performed. With increasing the temperature the irreversible regime of the magnetization cycles is rapidly restricted to low fields, showing that the critical current J(sub c) becomes strongly field dependent well below T(sub c). At 2.4 K the critical current in zero field, determined from the remanent magnetization by using the Bean formula for the critical state, is J(sub c) = 2 10(exp 5) A/sq cm. The temperature dependence of J(sub c) is satisfactorily described by the phenomenological law J(sub c) = J(sub c) (0) (1 - T/T(sub c) (sup n), with n = 8. The time decay of the zero field cooled magnetization and of the remanent magnetization was studied at different temperatures for different magnetic fields. The time decay was found to be logarithmic in both cases, at least at low temperatures. At T = 4.2 K for a field of 10 kOe applied parallel to the c axis, the average pinning energy, determined by using the flux creep model, is U(sub o) = 0.010 eV.

Agostinelli, E.↗

On the size of the cometary tail magnetic field

Ershkovich's (1978) criticism of previous arguments in favor of magnetic fields of approximately 100 gammas in cometary plasma tails are shown to be unjustified. It is argued that the folding velocity of tail streamers indicates a substantial tail magnetic field and that much of Ershkovich's disagreement stems from the choice of completely different models for a comet's plasma tail. It is concluded that the use of growth rates or phase-velocity information obtained from a dispersion relation to interpret large-amplitude disturbances, such as those in comet tails, is categorically incorrect.

Mendis, D. A.↗

Virial theorem analysis of the structure and stability of magnetized clouds

The tensor virial theorem is used to analyze the structure and stability of self-gravitating, magnetized spheroids surrounded by a low-density medium with pressure and magnetic field. Analytical expressions are developed for the effect of a weak field and calculate critical states when the effect of the field is arbitrarily strong, comparing the results with full magnetohydrostatic calculations. This analysis suggests that a magnetic field may prevent gravitational collapse but may also be destabilizing, depending on its degree of concentration within the cloud.

Zweibel, Ellen G.↗

Virial theorem analysis of the structure and stability of magnetized clouds

The tensor virial theorem is used to analyze the structure and stability of self-gravitating, magnetized spheroids surrounded by a low-density medium with pressure and magnetic field. Analytical expressions are developed for the effect of a weak field and calculate critical states when the effect of the field is arbitrarily strong, comparing the results with full magnetohydrostatic calculations. This analysis suggests that a magnetic field may prevent gravitational collapse but may also be destabilizing, depending on its degree of concentration within the cloud.

Zweibel, Ellen G.↗

Flux flow and flux dynamics in high-T(sub c) superconductors

Because high temperature superconductors, including BYCO and BSCCO, are type 2 superconductors with relatively low H(sub c 1) values and high H(sub c 2) values, they will be in a critical state for many of their applications. In the critical state, with the applied field between H(sub c 1) and H(sub c 2), flux lines have penetrated the material and can form a flux lattice and can be pinned by structural defects, chemical inhomogeneities, and impurities. A detailed knowledge of how flux penetrates the material and its behavior under the influence of applied fields and current flow, and the effect of material processing on these properties, is required in order to apply, and to improve the properties of, these superconductors. When the applied field is changed rapidly, the time dependence of flux change can be divided into three regions, an initial region which occurs very rapidly, a second region in which the magnetization has a 1n(t) behavior, and a saturation region at very long times. A critical field is defined for depinning, H(sub c,p) as that field at which the hysteresis loop changes from irreversible to reversible. As a function of temperature it is found that H(sub c,p) is well described by a power law with an exponent between 1.5 and 2.5. The behavior of H(sub c,p) for various materials and its relationship to flux flow and flux dynamics are discussed.

Bennett, L. H.↗

Flux flow and flux dynamics in high-Tc superconductors

Because high temperature superconductors, including BYCO and BSSCO, are type 2 superconductors with relatively low H(sub c 1) values and high H(sub c 2) values, they will be in a critical state for many of their applications. In the critical state, with the applied field between H(sub c 1) and H(sub c 2), flux lines have penetrated the material and can form a flux lattice and can be pinned by structural defects, chemical inhomogeneities, and impurities. A detailed knowledge of how flux penetrates the material and its behavior under the influence of applied fields and current flow, and the effect of material processing on these properties, is required in order to apply, and to improve the properties of these superconductors. When the applied field is changed rapidly, the time dependence of flux change can be divided into three regions, an initial region which occurs very rapidly, a second region in which the magnetization has a 1n(t) behavior, and a saturation region at very long times. A critical field is defined for depinning, H(sub c,p) as that field at which the hysteresis loop changes from irreversible to reversible. As a function of temperature, it is found that H(sub c,p) is well described by a power law with an exponent between 1.5 and 2.5. The behavior of H(sub c,p) for various materials and its relationship to flux flow and flux dynamics are discussed.

Bennett, L. H.↗

Critical currents in sputtered PbMo6S8

Critical currents in sputtered Chevrel-phase lead molybdenum sulfide have been measured at several temperatures as a function of applied magnetic field up to 19 T. A critical current density of approximately 50 million A/sq m was obtained at 15 T and 1.8 K, and the effective upper critical field was estimated to be 30 T. The pinning force at low fields was found to be dependent on the amount of free lead.

Alterovitz, S. A.↗

Narrow-field radiometry in a quasi-isotropic atmosphere

If a radiometer having a narrow field of view is used to measure the radiance of a source such as a quasi-isotropic atmosphere, a knowledge of the out-of-field responsivity is critical. For example, if a radiometer with a field of view of 5 deg (full-angle) has a relative responsivity of 0.0001 for the out-of-field radiation, the contribution of the out-of-field radiation (assuming an isotropic source subtending 2 steradians) is 10.5% of the total signal. Either the stray light suppression of the radiometer must be extremely high or methods of determining the out-of-field response must be developed. A description of one method of determining the effect of out-of-field response and its application to a planetary atmospheric radiometer is presented.

Holmes, A.↗

Configuration and Evaluation of a Dual-Doppler 3-D Wind Field System

Current LSP, GSDO, and SLS space vehicle operations are halted when wind speeds from specific directions exceed defined thresholds and when lightning is a threat. Strong winds and lightning are difficult parameters for the 45th Weather Squadron (45 WS) to forecast, yet are important in the protection of customer vehicle operations and the personnel that conduct them. A display of the low-level horizontal wind field to reveal areas of high winds or convergence would be a valuable tool for forecasters in assessing the timing of high winds, or convection initiation and subsequent lightning occurrence. This is especially important for areas where no weather observation platforms exist. Developing a dual-Doppler radar capability would provide such a display to assist forecasters in predicting high winds and convection initiation. The wind fields can also be used to initialize a local mesoscale numerical weather prediction model to help improve the model forecast winds, convection initiation, and other phenomena. The 45 WS and NWS MLB tasked the Applied Meteorology Unit (AMU) to develop a dual- Doppler wind field display using data from the 45th Space Wing radar, known as the Weather Surveillance Radar (WSR), NWS MLB Weather Surveillance Radar 1988 Doppler (KMLB), and the Orlando International Airport Terminal Doppler Weather Radar (KMCO). They also stipulated that the software used should be freely available. The AMU evaluated two software packages and, with concurrence from NWS MLB and the 45 WS, chose the Warning Decision Support System-Integrated Information (WDSS-II). The AMU collected data from two significant weather cases: a tornadic event on 14 April 2013 and a severe wind and hail event on 12 February 2014. For the 14 April case, the data were from WSR and KMLB. For the 12 February case, the data were from KMCO and KMLB. The AMU installed WDSS-II on a Linux PC, then processed and quality controlled the radar data for display and analysis using WDSS-II tools. Because of issues with de-aliasing the WSR velocity field, the AMU did not use data from this radar in this study and only analyzed the 12 February case. Merging the data to create the dual-Doppler analysis involved several steps. The AMU used instructions from the WDSS-II website and discussion forum to determine the correct tools to use for the analysis, and was successful in creating a merged reflectivity field, which was critical to the success of creating a merged velocity field. However, the AMU was unable to create a merged velocity field. The AMU researched the WDSS-II forum for discussions on similar issues, asked questions on the forum, and tested different options and values in the merger tool with no success. Developing a dual-Doppler wind field was the main goal of this task, but that was not accomplished. It could be an issue of not using the correct options or the correct value for the options used, or there could be issues with the radar data. There is a follow-on AMU task to install the operational version of WDSS-II in the NWS MLB office. This will provide more opportunities to try different options and input values in order to create a merged wind field from KMCO and KMLB.

Doppler radar↗

The physics of solar prominences

The outstanding questions on the formation of quiescent prominences are discussed. One key issue is identified to be the formation of dips in coronal magnetic field lines. A model is presented which can account for such dipped field lines. The critical ingredients of the model are that the prominence magnetic field is a truly three dimensional structure with significant variation along the prominence length, and the magnetic field has strong shear concentrated at the photospheric neutral line. Simulations which demonstrate that these two features lead to dip formation and that the geometry of the dips are such that inverse polarity prominences can be explained are presented. Another key issue is identified to be the formation of prominence condensations on dipped field lines. It is argued that a spatially varying coronal heating rate which is maximum near the chromosphere explain these condensations.

Antiochos, Spiro K.↗

Critical component of the interplanetary magnetic field responsible for large geomagnetic effects in the polar cap

An observed influence is studied of the interplanetary magnetic sector structure on the geomagnetic variations in the polar cap which appears to be due to the component of the interplanetary magnetic field near the ecliptic perpendicular to the earth-sun direction. It is suggested that the observed effect on the ground originates in the front of the magnetosphere.

Friis-Christensen, E.↗