Angiogenesis and wound healing in mice exposed to reduced barometric pressure /345 mm Hg/.
Altitude hypoxia as stimulant of new blood vessel formation /angiogenesis/ and wound healing in mice
Anthony, A.↗
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Results for “Blood Vessel”
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The dissipation and dispersion of small waves in arteries and veins with viscoelastic wall properties.
HF pressure waves dispersion in blood vessels ascribed to viscoelastic behavior of walls
Anliker, M.↗
Dispersion and attenuation of small artificial pressure waves in the canine aorta.
Elastic behavior of large blood vessels in canine aorta by measuring dispersion and attenuation of artificially induced pressure waves
Anliker, M.↗
Non-contact method of measuring small eye- movements and stabilizing the retinal image.
Small eye movements measurement and retinal image stabilization based on tracking edge of blood vessel in optic disk
Cornsweet, T. N.↗
Single-channel pressure telemetry unit.
Single channel pressure telemetry unit for chronic implantation into cardiac chambers or major blood vessels in unrestrained animals for measuring ventricular pressure
Datnow, B.↗
Pulsatile Newtonian frictional losses in a rigid tube.
Analytic expressions for the instantaneous average velocity and friction factor have been obtained for pulsatile Newtonian laminar flow with mean flow. Experimental pulsatile pressure gradients were found to be complex wave forms whose characteristics strongly influenced the experimental pulsatile average velocity and friction factor. Experimental and theoretical reduced instantaneous friction factor histories varied in a non-sinusoidal manner throughout the pulse cycle and exhibited extremum points. At high pulsation pressure ratios, substantial deviation occurred in the portion of the pulse cycle where the instantaneous average velocity approached zero. At low pulsation pressure ratios, the experimental and theoretical time average friction factor equaled unity and was independent of pulsation modulus. One potential application of this result is in the study of blood flow through small blood vessels.
Phillips, E. M.↗
Collaborative research in cardiovascular dynamics and bone elasticity
A collaborative research program covering a variety of topics of biomechanics and biomedical engineering within the fields of cardiovascular dynamics, respiration, bone elasticity and vestibular physiology is described. The goals of the research were to promote: (1) a better understanding of the mechanical behavior of the circulatory system and its control mechanisms; (2) development of noninvasive methods of measuring the changes in the mechanical properties of blood vessels and other cardiovascular parameters in man; (3) application of these noninvasive methods to examine in man the physiological effects of environmental changes, including earth-simulated gravitational changes; and (4) development of in-flight methods for studying the events which lead to post-flight postural hypotension.
Source record↗
Morphology of the internal organs in the adaptation of animals to high-altitude conditions
Disruption of metabolic processes in the walls of the blood vessels as well as changes in the functional activity of the endocrine glands play an important role in the process of an animal's accommodation to a combination of stress factors. Preliminary training of animals for stays at high-altitude markedly reduces the severity of the morphological picture.
Rakhimov, Y. A.↗
Development of ultrasonic methods of hemodynamic measurements
A pulsed ultrasonic Doppler velocity meter which can be used (by modifying transducers) as a flowmeter for blood circulation was experimentally studied. Calculations and profiles of turbulent and laminar flow within blood vessels are shown. Graphs and charts of transducers are included.
Histand, M. B.↗
Flow and pressure regulation in the cardiovascular system
Principles and descriptive fragments which may contribute to a model of the regulating chains in the cardiovascular system are presented. Attention is given to the strain sensitivity of blood vessels, the law of the autonomy of the heart beat oscillator, the law of the encapsulation of body fluids, the law of the conservation of protein, the law of minimum 'arterial' pressure, the design of the 'mammalian' kidney, questions of homeokinetic organization, and the development of self-regulatory chains. Details concerning the development program for the heart muscle are considered along with the speed of response of the breathing rate and the significance of the pulmonary vascular pressure-flow characteristics.
Iberall, A.↗
Tutorial: angiocardiography, past and present
The contribution of X-ray methodology and angiocardiography in the ability to study cardiac and cardiovascular function is presented. Angiocardiography remains the most reliable method for determination of overall chamber size and shape particularly in the face of disease states of varying etiologies. It also presents the most accurate means for obtaining dimensional information concerning the heart and blood vessels without the use of surgery or attachment of transducers.
Sandler, H.↗
In vivo blood-flow mapping
Application of laser doppler techniques to commercially available, low loss fiber optics allows direct reading of blood velocity within tiny blood vessels.
Frazer, R. E.↗
High-resolution echocardiography
High resolution computer aided ultrasound system provides two-and three-dimensional images of beating heart from many angles. System provides means for determining whether small blood vessels around the heart are blocked or if heart wall is moving normally without interference of dead and noncontracting muscle tissue.
Nathan, R.↗
Temperature uniformity in hyperthermal tumor therapy
Mouse mammary tumors heated by water bath or by microwave-induced hyperthermia exhibit a response that varies sharply with treatment temperature; therefore, uniform heating of the tumor is essential to quantitate the biological response as a function of temperature. C3H tumors implanted on the mouse flank were easily heated to uniformities within 0.1 C by using water baths. Cold spots up to 1 C below the desired treatment temperature were observed in the same tumors implanted on the hind leg. These cold spots were attributed to cooling by major blood vessels near the tumor. In this case temperature uniformity was achieved by the deposition of 2450 MHz microwave energy into the tumor volume by using parallel-opposed applicators.
Harrison, G. H.↗
Modification of a Kowa RC-2 fundus camera for self-photography without the use of mydriatics
Research on retinal circulation during space flight required the development of a simple technique to provide self monitoring of blood vessel changes in the fundus without the use of mydriatics. A Kowa RC-2 fundus camera was modified for self-photography by the use of a bite plate for positioning and cross hairs for focusing the subject's retina relative to the film plane. Dilation of the pupils without the use of mydriatics was accomplished by dark-adaption of the subject. Pictures were obtained without pupil constriction by the use of a high speed strobe light. This method also has applications for clinical medicine.
Philpott, D. E.↗
Pulse transducer with artifact signal attenuator
An artifact signal attenuator for a pulse rate sensor is described. The circuit for attenuating background noise signals is connected with a pulse rate transducer which has a light source and a detector for light reflected from blood vessels of a living body. The heart signal provided consists of a modulated dc signal voltage indicative of pulse rate. The artifact signal resulting from light reflected from the skin of the body comprises both a constant dc signal voltage and a modulated dc signal voltage. The amplitude of the artifact signal is greater and the frequency less than that of the heart signal. The signal attenuator circuit includes an operational amplifier for canceling the artifact signal from the output signal of the transducer and has the capability of meeting packaging requirements for wrist-watch-size packages.
Cash, W. H., Jr.↗
Micro-fluid exchange coupling apparatus
In a macro-fluid exchange, a hollow needle, such as a syringe needle, is provided for penetrating the fluid conduit of the animal. The syringe needle is coupled to a plenum chamber having an inlet and outlet port. The plenum chamber is coupled to the syringe needle via the intermediary of a standard quick disconnect coupling fitting. The plenum chamber is carried at the end of a drive rod which is coupled to a micrometer drive head. The micrometer drive head is slidably and pivotably coupled to a pedestal for adjusting the height and angle of inclination of the needle relative to a reference base support. The needle is positioned adjacent to the incised trachea or a blood vessel of a small animal and the micrometer drive head is operated for penetrating the fluid conduit of the animal.
Johnson, J. E., Jr.↗
Late biological effects of heavy charged particles: Cataracts, vascular injury and life shortening in mice
Risks associated with extended habitation in a space environment, particularly hazards to space workers that might result from exposure to high energy heavy ion particles (HZE), were studied. Biological effects of HZE were investigated in mice to assess their potential adverse health hazards. The potential effects of HZE particles on the crystalline lens of the eye and the carcinogenic effects and blood vessel (vascular) damage from radiation were evaluated by a risk assessment. Animal experiments to evaluate dose response relationships for tumor induction/promotion and for vascular injury were introduced. Cataract productions and preliminary results on cacinogenic and vascular effects are presented for perspective.
Ainsworth, E. J.↗