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All sourcesNASA NTRSDOE OSTI
NASA NTRS2024

The CapiSorb Visible System (CVS) Demonstrations on ISS

Falling liquid film amine sorbent reactors have been successfully employed to scrub CO 2 aboard submarines for decades. However, applying such proven methods aboard orbiting and coast spacecraft is significantly challenged by the nearly weightless environment, where liquid sprays and films do not fall, and vapor bubbles and gases do not rise. The Capillary Sorbent (CapiSorb) Visible System (CVS) is a technology demonstration experiment performed aboard the ISS April 18 – 21, 2023. The system establishes stable steady thin liquid film flows in Contactor (absorber) and Degasser (desorber/stripper) replacing the passive role of gravity with the combined passive roles of surface tension, wetting, and system geometry. A TOX-0 fructose ersatz liquid sorbent is employed enabling ‘transparent’ experiments performed and filmed by the crew safely in the open cabin of the ISS. Completed objectives include demonstrations of stable passive ‘massively’ parallel planar thin film capillary flows across atmospheric pressure Contactor and sealed heated Degasser. The impacts of varying flow rate, flow direction, heat input, viscosity, positive and negative Degasser pressures, condensate collection and return, fluid distribution, interfacial stability, and others are reported. At least 49 diagnostics are recorded for digitization and subsequent thermal-fluids model validation by a single HD video downlink during the nearly 22 hours of operations. An overview of the flight hardware including description of the components, diagnostics, crew procedures, flight operations, and summary of accomplishments is reported in Ref. 1. Further details of the diagnostics, tests performed, and data reduction is reported in Ref. 2. This report collects both1,2 into a single report adding methods of data digitization, reduction, and archive along with analyses and discussions of technology impacts.

microgravity↗
NASA NTRS2001

Innovative Technologies for a Space Station Microgravity Furnace

Several Innovations were developed for a high gradient directional solidification vacuum furnace with quench capability, called the Quench Module Insert. The QMI hot zone employs advanced heater elements in a multiple zone configuration and uses a novel instrumentation approach for temperature control. A fiber interface material provides a low friction, high heat extraction interface between a reconfigurable cold zone and the science sample. The quench utilizes a metal phase change to provide rapid, resource efficient quenching of science samples. This paper provides conceptual details and performance data on these innovations.

Carswell, B.↗
NASA NTRS1995

Dynamic analysis of astronaut motions in microgravity: Applications for Extravehicular Activity (EVA)

Simulations of astronaut motions during extravehicular activity (EVA) tasks were performed using computational multibody dynamics methods. The application of computational dynamic simulation to EVA was prompted by the realization that physical microgravity simulators have inherent limitations: viscosity in neutral buoyancy tanks; friction in air bearing floors; short duration for parabolic aircraft; and inertia and friction in suspension mechanisms. These limitations can mask critical dynamic effects that later cause problems during actual EVA's performed in space. Methods of formulating dynamic equations of motion for multibody systems are discussed with emphasis on Kane's method, which forms the basis of the simulations presented herein. Formulation of the equations of motion for a two degree of freedom arm is presented as an explicit example. The four basic steps in creating the computational simulations were: system description, in which the geometry, mass properties, and interconnection of system bodies are input to the computer; equation formulation based on the system description; inverse kinematics, in which the angles, velocities, and accelerations of joints are calculated for prescribed motion of the endpoint (hand) of the arm; and inverse dynamics, in which joint torques are calculated for a prescribed motion. A graphical animation and data plotting program, EVADS (EVA Dynamics Simulation), was developed and used to analyze the results of the simulations that were performed on a Silicon Graphics Indigo2 computer. EVA tasks involving manipulation of the Spartan 204 free flying astronomy payload, as performed during Space Shuttle mission STS-63 (February 1995), served as the subject for two dynamic simulations. An EVA crewmember was modeled as a seven segment system with an eighth segment representing the massive payload attached to the hand. For both simulations, the initial configuration of the lower body (trunk, upper leg, and lower leg) was a neutral microgravity posture. In the first simulation, the payload was manipulated around a circular trajectory of 0.15 m radius in 10 seconds. It was found that the wrist joint theoretically exceeded its ulnal deviation limit by as much as 49. 8 deg and was required to exert torques as high as 26 N-m to accomplish the task, well in excess of the wrist physiological limit of 12 N-m. The largest torque in the first simulation, 52 N-m, occurred in the ankle joint. To avoid these problems, the second simulation placed the arm in a more comfortable initial position and the radius and speed of the circular trajectory were reduced by half. As a result, the joint angles and torques were reduced to values well within their physiological limits. In particular, the maximum wrist torque for the second simulation was only 3 N-m and the maximum ankle torque was only 6 N-m.

Newman, Dava J.↗
NASA NTRS1983

Future thrusts in life sciences experimentation in space

Biomedical research objectives for future Shuttle and/or Space Station missions are discussed, with a focus on experiments exploring the physiological effects of microgravity. Experience up to the present is found to indicate that molecular-level processes are not much affected by the space environment, so that future experiments should concentrate on larger-scale phenomena. Areas considered include cardiovascular, respiratory, skeletal, and muscular physiology; metabolism; neurophysiology; and behavior. Radiation effects are seen as well as understood on the basis of ground-based data, with the possible exception of HZE-particle radiation. The need for carefully constructed ground research to prepare for space experiments is stressed.

Dietlein, L. F.↗
NASA NTRS1998

The Implications of Reduced Ground Reaction Forces During Space Flight for Bone Strains

The specific mechanisms regulating bone mass are not known, but most investigators agree that bone maintenance is largely dependent upon mechanical demand and the resultant local bone strains. During space flight, bone loss such as that reported by LeBlanc et al. may result from failure to effectively load the skeleton and generate sufficient localized bone strains. In microgravity, a gravity replacement system can be used to tether an exercising subject to a treadmill. It follows that the ability to prevent bone loss is critically dependent upon the external ground reaction forces (GRFs) and skeletal loads imparted by the tethering system. To our knowledge, the loads during orbital flight have been measured only once (on STS 81). Based on these data and data from ground based experiments, it appears likely that interventions designed to prevent bone loss in micro-gravity generate GRFs substantially less than body weight. It is unknown to what degree reductions in external GRFs will affect internal bone strain and thus the bone maintenance response. To better predict the efficacy of treadmill exercise in micro-gravity we used a unique cadaver model to measure localized bone strains under conditions representative of those that might be produced by a gravity replacement system in space.

Peterman, Marc M.↗
NASA NTRS2024

Findings From 9 Years of Renal Stone Surveillance of U.S. Astronauts

INTRODUCTION: Renal stones are thought to be a risk for spaceflight due to urine chemistry changes, induced by microgravity. Asymptomatic stone can have significant medical and mission impact.For9 years astronauts travelling to the International Space Station (ISS) have received pre-and post-flight renal ultrasound, according to a specialized renal ultrasound protocol, to look for renal calcifications or mineralized renal material (MRM).A new ultrasound machine was put in service halfway through the screening program. METHODS: MRM screening data from pre-and post-flight were compared, to look for changes in MRM burden. Pre-and post-flight scans from 42 subjects were compared. Studies were further stratified by old versus new machine. Measures were modeled using the analysis of variance (ANOVA) as defined by the interaction between pre-to postflight, and machine-to-machine. RESULTS: There was no observed statistical change seen in MRM burden pre-to postflight using the new higher-resolution ultrasound machine. DISCUSSION: The new machine gives more precise measurements and allows us to differentiate MRMs from other bright objects seen on ultrasound, such as small blood vessels. These data imply that spaceflight does not increase the risk of renal stone formation, at least out to the length of ISS missions. This data will be used to update NASA’s Human System Risk Board’s risk tracking documents, in-flight Concept of Operations, and our Clinical Practice Guideline.

K Cortez↗
NASA NTRS2007

Renal Stone Risk During Space Flight: Assessment and Countermeasure Validation

NASA has focused its future on exploration class missions including the goal of returning to the moon and landing on Mars. With these objectives, humans will experience an extended exposure to the harsh environment of microgravity and the associated negative effects on all the physiological systems of the body. Exposure to microgravity affects human physiology and results in changes to the urinary chemical composition during and after space flight. These changes are associated with an increased risk of renal stone formation. The development of a renal stone would have health consequences for the crewmember and negatively impact the success of the mission. As of January 2007, 15 known symptomatic medical events consistent with urinary calculi have been experienced by 13 U.S. astronauts and Russian cosmonauts. Previous results from both MIR and Shuttle missions have demonstrated an increased risk for renal stone formation. These data have shown decreased urine volume, urinary pH and citrate levels and increased urinary calcium. Citrate, an important urinary inhibitor of calcium-containing renal stones binds with calcium in the urine, thereby reducing the amount of calcium available to form calcium oxalate stones. Urinary citrate also prevents calcium oxalate crystals from aggregating into larger crystals and into renal stones. In addition, citrate makes the urine less acidic which inhibits the development of uric acid stones. Potassium citrate supplementation has been successfully used to treat patients who have formed renal stones. The evaluation of potassium citrate as a countermeasure has been performed during the ISS Expeditions 3-6, 8, 11-13 and is currently in progress during the ISS Expedition 14 mission. Together with the assessment of stone risk and the evaluation of a countermeasure, this investigation provides an educational opportunity to all crewmembers. Individual urinary biochemical profiles are generated and the risk of stone formation is estimated. Increasing fluid intake is recommended to all crewmembers. These results can be used to lower the risk for stone formation through lifestyle, diet changes or therapeutic administration to minimize the risk for stone development. With human presence in microgravity a continuing presence and exploration class missions being planned, maintaining the health and welfare of all crewmembers is critical to the exploration of space.

Whitson, P. A.↗
NASA NTRS1985

A Fundamental Study of Smoldering with Emphasis on Experimental Design for Zero-G

The objective of this section of the microgravity project is to identify key sets of low-gravity experiments which would critically compliment a larger set of more easily performed normal-gravity experiments to explain the phenomena found in smoldering combustion. It is planned to follow through on the conceptual design of these experiments by participating in the future in the fabrication of the refined apparatus and in the data collection and interpretation. Low-gravity experiments are appropriate for smoldering combustion because of the complexity of smoldering which requires every means possible to discriminate among the many chemical and physical mechanisms active in most smoldering combustion scenarios. Efforts will be primarily analytical, attempting to identify appropriate approximations and dominant dimensionless groups based on existing data and state-of-the-art combustion modelling. Transient stability questions such as ignition, extinction and the choices among charring, tarring, or flaming modes will be included.

Pagni, P. J.↗
NASA NTRS1999

Viscosity Measurement using Drop Coalescence in Microgravity

We present in here details of a new method, using drop coalescence, for application in microgravity environment for determining the viscosity of highly viscous undercooled liquids. The method has the advantage of eliminating heterogeneous nucleation at container walls caused by crystallization of undercooled liquids during processing. Also, due to the rapidity of the measurement, homogeneous nucleation would be avoided. The technique relies on both a highly accurate solution to the Navier-Stokes equations as well as on data gathered from experiments conducted in near zero gravity environment. The liquid viscosity is determined by allowing the computed free surface shape relaxation time to be adjusted in response to the measured free surface velocity of two coalescing drops. Results are presented from two validation experiments of the method which were conducted recently on board the NASA KC-135 aircraft. In these tests the viscosity of a highly viscous liquid, such as glycerine at different temperatures, was determined to reasonable accuracy using the liquid coalescence method. The experiments measured the free surface velocity of two glycerine drops coalescing under the action of surface tension alone in low gravity environment using high speed photography. The free surface velocity was then compared with the computed values obtained from different viscosity values. The results of these experiments were found to agree reasonably well with the calculated values.

Antar, Basil N.↗
NASA NTRS1991

Life sciences get important new data from Spacelab mission. III

An investigation of the effects of weightlessness on the human body is reported that was conducted on a flight of the Space Shuttle Columbia. Experiments are described regarding zero-gravity effects on the human perception of balance, the growth of lymphocytes, and general life-sciences examinations of body mass, body fluid, pulmonary parameters, and echocardiograph imaging. Specific attention is given to the day-to-day operations of the mission, and particular emphasis is given to the study of rodents and jellyfish reacting to microgravity.

Schuiling, Roelof L.↗
NASA NTRS1992

Development of and flight results from the Space Acceleration Measurement System (SAMS)

Described here is the development of and the flight results from the Space Acceleration Measurement System (SAMS) flight units used in the Orbiter middeck, Spacelab module, and the Orbitercargo bay. The SAMS units are general purpose microgravity accelerometers designed to support a variety of science experiments with microgravity acceleration measurements. A total of six flight units have been fabricated; four for use in the Orbiter middeck and Spacelab module, and two for use in the Orbiter cargo bay. The design of the units is briefly described. The initial two flights of SAMS units on STS-40 (June 1991) and STS-43 (August 1991) resulted in 371 megabytes and 2.6 gigabytes of data respectively. Analytical techniques developed to examine this quantity of acceleration data are described and sample plots of analyzed data are illustrated. Future missions for the SAMS units are listed.

Delombard, Richard↗
NASA NTRS1992

Development of and flight results from the Space Acceleration Measurement System (SAMS)

This paper describes the development of and flight results from the Space Acceleration Measurement System (SAMS) flight units used in the Orbiter middeck, Spacelab module and the Orbiter cargo bay. The SAMS units are general purpose microgravity accelerometers designed to support a variety of science experiments with microgravity acceleration measurements. A total of six flight units have been fabricated; four for use in the Orbiter middeck and Spacelab module, and two for use in the Orbiter cargo bay. The design of the units is briefly described. The initial two flights of SAMS units on STS-40 (June 1991) and STS-43 (August 1991) resulted in 371 megabytes and 2.6 gigabytes of data, respectively. Analytical techniques developed to examine this quantity of acceleration data are described and sample plots of analyzed data are illustrated. Future missions for the SAMS units are listed.

Delombard, Richard↗
NASA NTRS1999

A Study of Flame Propagation on Water-Mist Laden Gas Mixtures in Microgravity

The use of water mists (very fine water sprays) for fire suppression is currently receiving increased attention as a replacement technology for halogen-based chemical agents-such as Halon 1301 (CF3Br)--the manufacturing of which has been banned by the Montreal Protocol due to their high ozone depletion potential. Water mist technology has been found effective for a wide range of applications such as Class B pool fires, shipboard machinery, aircraft cabins, computers, and electronic equipment. There are five distinct mechanisms by which water droplets may interact with a flame. First, the high enthalpy of vaporization of water (2450 kJ/kg) leads to heat removal from the flame front as the liquid droplets turn to steam. Second, as water vaporizes its volume increases approximately three orders of magnitude, which leads to the dilution of the oxygen and vaporized fuel required to maintain the flame. The third effect is the recombination of H-atoms and other radicals on the droplet surface. A fourth effect of water mists in fires is the retardation of surface propagation rates due to the wetting of walls and surfaces. The last potential impact of fine water mists affects the radiative propagation of the fire by forming an optically thick barrier to infrared radiation which prevents ignition of the unburned regions. Unfortunately, little fundamental information exists on the interaction of a flame with a water mist. To date, there is no widely accepted interpretation of the critical concentration of droplets required to suppress a flame or of the fundamental mechanisms involved in flame extinguishment by water mists. One of the main obstacles to obtaining such understanding is the difficulty of providing a simple, well-defined experimental setup for the flame front/water mist interaction. Some of the difficulty stems from the problem of generating, distributing and maintaining a homogeneous concentration of droplets throughout a chamber while gravity depletes the concentration and alters the droplet size by coalescence and agglomeration mechanisms. Experiments conducted in the absence of gravity provide an ideal environment to study the interaction of water mists and flames by eliminating these distorting effects. In addition, microgravity eliminates the complex flow patterns induced between the flame front and the water droplets. The long duration and quality of microgravity in space flights provide the required conditions to perform the setup and monitoring of flame suppression experiments. Consequently, a series of experiments have been identified to be performed on the Combustion Module (CM-2) in the Space Shuttle. These consist of measuring the extinguishing capability of a water mist on a premixed flame propagating along a tube. These experiments should provide the necessary data to obtain further understanding of the water mist suppression phenomena that can be later used to design and manufacture appropriate fire suppression systems. In preparation for the orbital flights, experiments have been conducted on low-gravity ground facilities to obtain the preliminary data necessary to define the scientific objectives and technical issues of the spacecraft experiments.

Abbud-Madrid, A.↗
NASA NTRS1999

Space Experiment Module (SEM)

The Space Experiment Module (SEM) Program is an education initiative sponsored by the National Aeronautics and Space Administration (NASA) Shuttle Small Payloads Project. The program provides nationwide educational access to space for Kindergarten through University level students. The SEM program focuses on the science of zero-gravity and microgravity. Within the program, NASA provides small containers or "modules" for students to fly experiments on the Space Shuttle. The experiments are created, designed, built, and implemented by students with teacher and/or mentor guidance. Student experiment modules are flown in a "carrier" which resides in the cargo bay of the Space Shuttle. The carrier supplies power to, and the means to control and collect data from each experiment.

Brodell, Charles L.↗
NASA NTRS2001

The g-LIMIT Microgravity Vibration Isolation System for the Microgravity Science Glovebox

For many microgravity science experiments in the International Space Station, the ambient acceleration environment will be exceed desirable levels. To provide a more quiescent acceleration environment to the microgravity payloads, a vibration isolation system named g-LIMIT (GLovebox Integrated Microgravity Isolation Technology) is being designed. g-LIMIT is a sub-rack level isolation system for the Microgravity Science Glovebox that can be tailored to a variety of applications. Scheduled for launch on the UF-1 mission, the initial implementation of g-LIMIT will be a Characterization Test in the Microgravity Science Glovebox. g-LIMIT will be available to glovebox investigators immediately after characterization testing. Standard MSG structural and umbilical interfaces will be used so that the interface requirements are minimized. g-LIMIT consists of three integrated isolator modules, each of which is comprised of a dual axis actuator, two axes of acceleration sensing, two axes of position sensing, control electronics, and data transmission capabilities in a small-volume package. In addition, this system provides the unique capability for measuring quasi-steady acceleration of the experiment independent of accelerometers as a by-product of the control system and will have the capability of generating user-specified pristine accelerations to enhance experiment operations.

Whorton, Mark S.↗
NASA NTRS2002

Experimental Visualization of Bubble Formation from an Orifice In Microgravity in the Presence of Electric Fields

The formation of air bubbles injected into a stagnant, isothermal liquid in microgravity through an orifice was studied. The bubbles grew very large in microgravity. They attained a nearly spherical shape and showed pronounced affinity towards coalescence in the absence of electric fields and other perturbations. Under the influence of electric fields, periodic detachment was observed, with bubble sizes larger than in terrestrial conditions. The bubble shape was elongated. After detachment, the bubbles moved away from the electrode at which they formed without coalescing with other bubbles. Experimental data on bubble shape and size at detachment showed good agreement with models.

Herman, C.↗
NASA NTRS2015

Transient Gene and miRNA Expression Profile Changes of Confluent Human Fibroblast Cells in Space

Microgravity or an altered gravity environment from the static 1 gravitational constant has been shown to influence global gene expression patterns and protein levels in cultured cells. However, most of the reported studies conducted in space or using simulated microgravity on the ground have focused on the growth or differentiation of the cells. Whether non-dividing cultured cells will sense the presence of microgravity in space has not been specifically addressed. In an experiment conducted on the International Space Station, confluent human fibroblast cells were fixed after being cultured in space for 3 and 14 days for investigations of gene and miRNA (microRNA) expression profile changes in these cells. A fibroblast is a type of cell that synthesizes the extracellular matrix and collagen, the structural framework for tissues, and plays a critical role in wound healing and other functions. Results of the experiment showed that on Day 3, both the flown and ground cells were still proliferating slowly even though they were confluent, as measured by the expression of the protein Ki-67 positive cells, and the cells in space grew slightly faster. Gene and miRNA expression data indicated activation of NF(sub kappa)B (nuclear factor kappa-light-chain-enhancer of activated B cells) and other growth related pathways involving HGF and VEGF in the flown cells. On Day 14 when the cells were mostly non-dividing, the gene and miRNA expression profiles between the flight and ground samples were indistinguishable. Comparison of gene and miRNA expressions in the Day 3 samples in respect to Day 14 revealed that most of the changes observed on Day 3 were related to cell growth for both the flown and ground cells. Analysis of cytoskeleton changes by immunohistochemistry staining of the cells with antibodies for alpha-tubulin showed no difference between the flight and ground samples. Results of our study suggest that in true non-dividing human fibroblast cells, microgravity in space has little effect on the gene and miRNA expression. Gene and miRNA expression changes were observed in cells that were confluent, but still proliferating slowly. The faster growth in the flown cells was associated with the activation of NF(sub kappa)B pathways which triggers the expression of several growth factors and the suppression of the cell cycle checkpoint.

Zhang, Ye↗
NASA NTRS1986

Space station support of manned Mars missions

The assembly of a manned Mars interplanetary spacecraft in low Earth orbit can be best accomplished with the support of the space station. Station payload requirements for microgravity environments of .001 g and pointing stability requirements of less than 1 arc second could mean that the spacecraft may have to be assembled at a station-keeping position about 100 meters or more away from the station. In addition to the assembly of large modules and connective structures, the manned Mars mission assembly tasks may include the connection of power, fluid, and data lines and the handling and activation of components for chemical or nuclear power and propulsion systems. These assembly tasks will require the use of advanced automation and robotics in addition to Orbital Maneuvering Vehicle and Extravehicular Activity (EVA) crew support. Advanced development programs for the space station, including on-orbit demonstrations, could also be used to support manned Mars mission technology objectives. Follow-on studies should be conducted to identify space station activities which could be enhanced or expanded in scope (without significant cost and schedule impact) to help resolve key technical and scientific questions relating to manned Mars missions.

Holt, Alan C.↗