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At least 1,243 records · Page 69

Analysis of single-mode Richtmyer–Meshkov instability using high-order incompressible vorticity-streamfunction and shock-capturing simulations

In this study, two- and three-dimensional simulation results obtained using a new high-order incompressible, variable-density vorticity–streamfunction (VS) method and data from previous ninth-order weighted essentially nonoscillatory (WENO) shock-capturing simulations are used to investigate the nonlinear dynamics of single-mode Richtmyer–Meshkov instability using a model of a Mach 1.3 air(acetone)/SF6 shock tube experiment. A comparison of the density fields from both simulations with the experimental images demonstrates very good agreement in the large-scale structure with both methods but differences in the small-scale structure. The WENO method captures the small-scale disordered structure observed in the experiment, while the VS method partially captures such structure and yields a strong rotating core. The perturbation amplitude growth from the simulations generally agrees well with the experiment. The simulation bubble and spike amplitudes agree well at early times. At later times, the WENO bubble amplitude is smaller than the VS amplitude and vice versa for the spike amplitude. The predictions of nonlinear single-mode instability growth models are shown to agree with the simulation amplitudes at early-to-intermediate times but underpredict the amplitudes at later times in the nonlinear regime. Visualizations of the mass fraction and enstrophy isosurfaces, velocity and vorticity fields, and baroclinic vorticity production and vortex stretching terms from the three-dimensional simulations indicate that, with the exception of the small-scale structure within the rollups, the VS and WENO results are in good agreement.

42 ENGINEERING↗

The Compton-Getting effect for low energy particles

The traditional first-order Compton-Getting effect, which relates particle distributions as observed in two frames of reference moving with constant relative velocity, is inadequate for the description of low-energy particles (less than a few hundred keV/nucleon) in the solar system. An exact procedure is given for recovering both isotropic and anisotropic distributions in the solar wind frame from observations made in a spacecraft frame. The method is illustrated by analyzing a particle event observed by an experiment on IMP-7 on Oct. 31, 1972.

Ipavich, F. M.↗

The Compton-Getting effect for low energy particles

It was found that the traditional first-order Compton-Getting effect, which relates particle distributions as observed in two frames of reference moving with constant relative velocity, is inadequate for the description of low energy particles (less than a few hundred keV/nucleon) in the solar system. An exact procedure is given for recovering both isotropic and anisotropic distributions in the solar wind frame from observations made in a spacecraft frame. The method was illustrated by analyzing a particle event observed on IPM-7.

Ipavich, F. M.↗

Kepler Data Validation and Follow-up Programs

The approach that the Kepler Mission uses to remove false positive events and to validate the discoveries consists of two parts; data validation (DPI) and follow up observations program (FOP). DV consists of several methods of examining the data from the spacecraft observations. First, to rule out statistical fluctuations in the data, accept only signals that show 3 or more transits and that have a total signal-to-noise ratio that exceeds 7 sigma. Second. to identify small stellar companions to the target star, we check for secondary eclipses and determine if the transit characteristics are appropriate for a planetary companion. Third, check for background binaries that are in the target aperture. Here we measure the movement of the image centroid before, during, and after the transit. If the target is producing the signal, a dimming wi11 move the image centroid in a known direction and magnitude. If the signal comes from a nearby star, the amplitude and direction of the motion wi11 be different, This test is expected to rule out the hundreds of binary signals expected from background stars. The precision of the measurement depends on the stellar fluxes and positions but can be better than 0.01 pixel; i.e., 0.04". Those candidates that pass these tests are examined using ground-based telescopes and radial velocity spectrometers. First medium precision RV is used to rule out any remaining stellar companions. Then high spatial resolution imaging is used to check for nearby stars that are in the aperture- (The Kepler apertures depend on magnitude but are of order 36 sq are sec in area.) If no stars are present that quid generate the observed signal, then the candidate goes to a large telescope such as Keck, HET, or Wi1lilam Herschel for high precision observations to get the planet mass or an upper limit to it, if there are some stars in the aperture, then the photometric observations are employed to look for the transit by cane of the confounding stars. If none are seen, then the candidate is sent to a large telescope such as Keck

William, Borucki J.↗

Pre-Flight Assessment of Xenon Propellant Usage and Usage Uncertainty for the Psyche Mission

NASA’s Psyche mission will launch in 2022 and begin a 3.6-year cruise to the metallic asteroid Psyche, the largest metal asteroid in the solar system. All primary propulsion will be done with the flight-proven SPT-140 electric propulsion subsystem. The Psyche mission will feature the first use of Hall thrusters for a NASA mission, and the first use of Hall thrusters beyond cis-lunar space, which has presented some unique challenges. In this paper we describe the Psyche propellant feed system architecture, expected propellant usage for the mission, propellant gauging requirements, and challenges associated with propellant gauging. Data from two recent Maxar electric orbit-raising missions with SPT-140 thrusters are reviewed and used to assess in-flight performance. We develop a pressure-volume-temperature gauging method that incorporates the propellant temperature distributions observed in the flight data, and use this method to provide an improved quantitative understanding of in-flight propellant consumption rates and their uncertainties. The results are in excellent agreement with the results of standard Maxar gauging methods and we determine a propellant usage uncertainty of ± 7.1% 3σ based on flight telemetry. Additionally, we demonstrate that the bookkeeping method of propellant gauging accurately predicts the tank pressure flight data. This work has led to design changes in the Psyche spacecraft avionics that will further improve propellant gauging uncertainties, which is particularly important for later phases of the mission. Finally, we statistically combine the predicted propellant mass uncertainties from the two gauging methods and demonstrate that the system will meet the mission requirements for propellant uncertainty. Together, all of this work provides confidence that the Psyche mission can be successfully completed within the existing propellant budget and propellant tank capacity.

Baldwin, Jeff↗

Validation of SE-EPI-based T2 mapping for characterization of prostate cancer: a new method compared with the traditional CPMG method

Purpose: We aim to compare the results of spin echo–echo planar imaging (SE-EPI)-based T2 mapping with those of the conventional Carr–Purcell–Meiboom–Gill (CPMG) method and to investigate the potential validity of SE-EPI-T2 mapping for the characterization of prostate cancer (PCa). Methods: Our retrospective study included 42 PCa patients and 42 noncancer patients who underwent 3.0T MRI with b values ranging from 0 to 2000 s/mm{sup 2} and echo times (TEs) ranging from 32 to 100 ms before biopsies. Bland–Altman analysis was used to compare the agreement between the two methods. The correlations between CPMG-T2 values and SE-EPI-T2 values at different b values were determined by Spearman’s rho analysis or Pearson analysis. The Mann–Whitney U test and two-sample t tests were used to analyze the differences between the cancerous and noncancerous groups. Results: Substantial agreement regarding the measurements was observed between the two methods. The average correlation between the CPMG-T2 values and SE-EPI-T2 values was moderate and positive, and the best correlations were found at b = 200 s/mm{sup 2} in the noncancer group (r = 0.557, P = 0.000) and at b = 100 s/mm{sup 2} in the cancer group (r = 0.537, P = 0.000). In addition, statistically significant differences were found between the noncancer and cancer groups in T2 values and ADC values (diff TEs) (P = 0.000). Conclusions: Substantial agreement in the measurements was found between the SE-EPI method and CPMG method. SE-EPI-based T2 mapping has potential clinical value for the prostate and can be considered an alternative to the traditional CPMG-T2 mapping method.

62 RADIOLOGY AND NUCLEAR MEDICINE↗

Utilizing fluorescent life time imaging microscopy technology for identify carriers of BRCA2 mutation

Worldwide, more than one million women are diagnosed with breast cancer every year, making it the most common female malignancy in the developed world. Germline mutations in BRCA1 and BRCA2 genes are estimated to increase the risk for developing breast cancer by up to 87%. From a clinical point of view, identification of BRCA1 and BRCA2 mutation carriers offers an opportunity to early identify or prevent the development of malignancy; therefore the ability to determine which women are more likely to carry BRCA1 or BRCA2 mutations is of great importance. The available diagnostic tests for mutation analysis of BRCA1 and BRCA2 are time- and labor-intensive, expensive, and do not allow the identification of all the functional mutations. We utilized the Fluorescent lifetime (FLT) imaging microscopy method which allows recognizing different cell populations, in order to distinguish between lymphocytes from BRCA1 and BRCA2 mutation carriers and non-carrier women by using easily obtainable lymphocyte cells from peripheral blood. Our results demonstrate that cells originated from BRCA2-mutation carriers have significantly lower FLT values compared with BRCA1 mutation carriers and control cells. This simple, inexpensive and sensitive method may be utilized in the future to detect BRCA2 mutation carriers, particularly those bearing unknown functional mutations. - Highlights: • Fluorescent lifetime imaging microscopy (FLIM) technology can be used for recognizing BRCA mutation carriers. • Cells originated from BRCA2-mutation carriers have lower FLT values compared with BRCA1 mutation carriers and control cells. • The difference in FLT values were observed regardless irradiation. • FLIM method may be more informative in the detection of BRCA2-mutation carriers than BRCA1.

60 APPLIED LIFE SCIENCES↗

Modern version of the uncited 1938 experiment that first observed DT fusion

Experiments are described, and results are provided, for the duplication of the first-ever triton-deuterium (colloquially referred to as DT) fusion experiment accidentally performed by A.J. Ruhlig in 1938, but forgotten in the published scientific literature. Here, we find that Ruhlig overestimated the ratio of the triton-deuterium over deuteron-deuterium neutron yields in his secondary reaction (Reaction-in-Flight) experiment compared to modern theoretical calculations and our duplication of his experiment using modern neutron detection methods. Nevertheless, Ruhlig’s observation provided the motivation for the application of DT fusion after World War II and its more recent importance in peaceful energy production at DT fusion facilities around the world. Additionally, the experimental technique used in the present work provides a novel approach for checking on low-energy triton stopping powers in deuterium containing compounds.

73 NUCLEAR PHYSICS AND RADIATION PHYSICS↗

New Insights into the Chemical Composition of Five Oort Cloud Comets after Re-analysis of Their Infrared Spectra

We present revised results for the main molecular species in five Oort Cloud comets observed with near-infrared echelle grating spectrometer (NIRSPEC) at the Keck Observatory between 1999 and 2012 (C/1999 S4 (LINEAR), C/2001 A2 (LINEAR), C/2007 W1 (Boattini), C/2012 F6 (Lemmon), and C/2012 S1 (ISON)). The re-evaluation of these data shows the improvement of results in some of the data sets, in particular for comets observed and analyzed before the advent of new and revised fluorescence models and terrestrial retrieval methods introduced since 2011. We observe significant improvements in the resulting rotational temperatures and the production rates for all species, and in mixing ratios of minor species (relative to water). The re-analysis also allowed us to quantify species not analyzed previously, mostly due to the lack of molecular models (e.g., ammonia and formaldehyde). We note, however, that the improvement of these revised values is less substantial for comets observed (and/or analyzed) since 2010.

37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CH↗

Measurement and modeling of the multiwavelength optical properties of uncoated flame-generated soot

Optical properties of flame-generated black carbon (BC) containing soot particles were quantified at multiple wavelengths for particles produced using two different flames: a methane diffusion flame and an ethylene premixed flame. Measurements were made for (i) nascent soot particles,(ii) thermally denuded nascent particles, and (iii) particles that were coated and then thermally denuded, leading to the collapse of the initiallylacy, fractal-like morphology. The measured mass absorption coefficients(MACs) depended on soot maturity and generation but were similar between flames for similar conditions. For mature soot, here corresponding to particles with volume-equivalent diameters > ~ 160 nm, the MAC and absorption Ångström exponent (AAE) values were independent of particle collapse while the single-scatter albedo increased. The MAC values for these larger particles were also size-independent. The mean MAC value at 532 nm for larger particles was 9.1±1.1 m 2 g -1 , about 17 % higher than that recommended by Bond and Bergstrom (2006), and the AAE was close to unity. Effective, theory-specific complex refractive index(RI) values are derived from the observations with two widely used methods:Lorenz–Mie theory and the Rayleigh–Debye–Gans (RDG) approximation. Mietheory systematically underpredicts the observed absorption cross sections at all wavelengths for larger particles (with x >0.9 ) independent of the complex RI used, while RDG provides good agreement. (The dimensionless size parameter x = π d p / λ , where d p is particle diameter and λ is wavelength.) Importantly, this implies that the use of Mie theory within air quality and climate models, as is common, likely leads to under predictions in the absorption by BC, with the extent of underprediction depending on the assumed BC size distribution and complex RI used. We suggest that it is more appropriate to assume a constant,size-independent (but wavelength-specific) MAC to represent absorption by uncoated BC particles within models.

54 ENVIRONMENTAL SCIENCES↗

Effects of mass motions on solar emission measures inferred from transition-region emission lines

Extreme ultraviolet emission line intensities predicted by a numerical model which includes nonequilibrium ionization balance are used as input 'observational' intensities to calculate volume emission measures following a standard method which assumes ionization equilibrium. These 'observational' emission measures are then compared with the actual emission measure distribution in the atmospheric model. For static equilibrium models, the two sets of emission measures are in good agreement. When mass motions are present, the emission measures calculated from the line intensities differ significantly from the actual values.

Mariska, J. T.↗

Automatic Determination of the Conic Coronal Mass Ejection Model Parameters

Characterization of the three-dimensional structure of solar transients using incomplete plane of sky data is a difficult problem whose solutions have potential for societal benefit in terms of space weather applications. In this paper transients are characterized in three dimensions by means of conic coronal mass ejection (CME) approximation. A novel method for the automatic determination of cone model parameters from observed halo CMEs is introduced. The method uses both standard image processing techniques to extract the CME mass from white-light coronagraph images and a novel inversion routine providing the final cone parameters. A bootstrap technique is used to provide model parameter distributions. When combined with heliospheric modeling, the cone model parameter distributions will provide direct means for ensemble predictions of transient propagation in the heliosphere. An initial validation of the automatic method is carried by comparison to manually determined cone model parameters. It is shown using 14 halo CME events that there is reasonable agreement, especially between the heliocentric locations of the cones derived with the two methods. It is argued that both the heliocentric locations and the opening half-angles of the automatically determined cones may be more realistic than those obtained from the manual analysis

Pulkkinen, A.↗

New Insights into the Chemical Composition of Five Oort Cloud Comets After Re-analysis of their Infrared Spectra

We present revised results for the main molecular species in five Oort Cloud (OC) comets observed with NIRSPEC at the Keck Observatory between 1999 and 2012 (C/1999 S4 (LINEAR), C/2001 A2 (LINEAR), C/2007 W1 (Boattini), C/2012 F6 (Lemmon), and C/2012 S1 (ISON)). The re-evaluation of these data shows the improvement of results in some of the datasets, in particular for comets observed and analyzed before the advent of new and revised fluorescence models and terrestrial retrieval methods introduced since 2011. We observe significant improvements in the resulting rotational temperatures and production rates for all species, and in mixing ratios of minor species (relative to water). The re-analysis also allowed us to quantify species not analyzed previously, mostly due to the lack of molecular models (e.g., ammonia and formaldehyde). We note, however, that the improvement of these revised values is less substantial for comets observed (and/or analyzed) since 2010.

Manuela Lippi↗

Design of Hypervelocity Flow Generator (HFG) and Its Diagnostics

Ground facilities for hypersonic research are a key element for successful development of aerodynamically proven hypervelocity vehicles. Design concepts and diagnostics of a hypervelocity flow generator (HFG) were made as a test platform for hypersonic/hypervelocity spacecraft models at the NASA Langley Research Center. The HFG is a hypersonic flow field generator using optically heated gas which is blown into an 80 cu m vacuum chamber. The vacuum chamber is kept at a stable vacuum pressure with a combination of three large vacuum pumps, while the HFG is in the test mode. The HFG provides a relatively small test section with approximately a 20 cm window. This facility was designed to generate 2.45 km/sec of flow speed, and potentially generate a continuous flow with the nozzle and vacuum system. The window in test section provides a direct view of the shock wave around a model in order to measure temperature, pressure, and density profile within the shock layer. One of the key test goals under this project is to understand why the emission spectra from the standing shockwave plasma predicted by Lora-Loran codes are significantly different from the measured emission spectra from the Flight Investigation Reentry Environment (FIRE II) Flight. The correct estimate of the thermal loading on the leading edge of hypersonic vehicles greatly affects the aerodynamic design, the material selection for the vehicle, and the cooling requirement and can be obtained by the precise modeling of emission spectra from shockwave plasma. However, the estimation of thermal loading is not an easy task due to complex non-equilibrium radiative process within high temperature shock layers that still falls into a category of cold plasma. Direct flight experiments are the most desirable, but not a cost-effective approach. Analysis by computational fluid dynamics (CFD) offers many test flexibilities. However, the CFD codes must be fully tested and validated with experimental data before the codes are effectively used for practical design. Large discrepancies between experiments and codes appear in hypersonic/hypervelocity flow regimes at high altitudes of 60 km ~ 90 km. This HFG facility offers some important parameters for CFD code validation, such as collision cross-sections, relaxation times, reaction rate coefficients and transportation coefficients. The HFG test facility is based on the ejection flow of high temperature gas heated over to 3500 K through a nozzle. The tungsten gas chamber of the HFG is heated up to a desired temperature by a 60 kW optical power beam source. This system consists of an optical power source, a thermal chamber, an expansion nozzle, a test section, and an 80 cu m vacuum tank. 60 kW optical input power is obtained from the 150 kW Vortek arc lamp system (by Vortek Industries, Vancouver, Canada). This optical beam is focused to heat the gas chamber within which a flow media is heated. The maximum achievable temperature of the flow medium reached approximately 3500 K or even higher but is limited by the melting point of the chamber material used. The exhaust velocity through the nozzle was determined by the stagnation temperature and the molecular weight of the working medium at the test section. To provide design parameters, a NASA Chemical Equilibrium with Application (CEA) computer program is used for the simulation of aerothermal data. This CEA program can calculate chemical equilibrium and properties of complex mixtures using shock tube parameters. For nitrogen gas at 2666 K stagnation temperature, the maximum achievable velocity at the test section is approximately 2.45 km/sec which is within the range of the thermal velocity of 8000 K shock layer. Based on the calculation through the CEA program, the design parameters of a HFG were determined and implemented for the test section that includes an expansion nozzle. The installed test section of the experimental facility can sustain a condition of a re-entry vehicle from the Space at an altitude of 60-90 km. After installation of the HFG, the system was fully tested and its operational parameters were measured. An 80 cu m vacuum chamber of HFG was set at 1 torr level to keep a stable downstream condition. The pumping time to reach the minimum vacuum pressure (~ 1 torr) at the test chamber from atmospheric pressure was approximately an hour using Kinney (MBV-14000/MB -1600/KT-300) and Stokes (Model 1772 and 412) pumps. Such a setup condition allowed a continued stable operation of the HFG experiment with flowrates through 1-, 3-, or 5-mm diameters of nozzle throat. The flow characteristics of the HFG for various operating conditions were performed using a focused Schlieren method. At 0.8 torr chamber pressure, a barrel shock was observed at the test section. With a sphere obstacle of 12 mm diameter in the flow, a bow shock (~ 2-mm thickness) was observed by a focused Schlieren visualization method.

Hypervelocity flow↗

Inner Engineering Practices and Advanced 4-day Isha Yoga Retreat Are Associated with Cannabimimetic Effects with Increased Endocannabinoids and Short-Term and Sustained Improvement in Mental Health: A Prospective Observational Study of Meditators

Anxiety and depression are common in the modern world, and there is growing demand for alternative therapies such as meditation. Meditation can decrease perceived stress and increase general well-being, although the physiological mechanism is not well-characterized. Endocannabinoids (eCBs), lipid mediators associated with enhanced mood and reduced anxiety/depression, have not been previously studied as biomarkers of meditation effects. Our aim was to assess biomarkers (eCBs and brain-derived neurotrophic factor [BDNF]) and psychological parameters after a meditation retreat. Methods. This was an observational pilot study of adults before and after the 4-day Isha Yoga Bhava Spandana Program retreat. Participants completed online surveys (before and after retreat, and 1 month later) to assess anxiety, depression, focus, well-being, and happiness through validated psychological scales. Voluntary blood sampling for biomarker studies was done before and within a day after the retreat. The biomarkers anandamide, 2-arachidonoylglycerol (2-AG), 1-arachidonoylglycerol (1-AG), docosatetraenoylethanolamide (DEA), oleoylethanolamide (OLA), and BDNF were evaluated. Primary outcomes were changes in psychological scales, as well as changes in eCBs and BDNF. Results. Depression and anxiety scores decreased while focus, happiness, and positive well-being scores increased immediately after retreat from their baseline values (P < 0.001). All improvements were sustained 1 month after BSP. All major eCBs including anandamide, 2-AG, 1-AG, DEA, and BDNF increased after meditation by > 70% (P < 0.001). Increases of ≥20% in anandamide, 2-AG, 1-AG, and total AG levels after meditation from the baseline had weak correlations with changes in happiness and well-being. Conclusions. A short meditation experience improved focus, happiness, and positive well-being and reduced depression and anxiety in participants for at least 1 month. Participants had increased blood eCBs and BDNF, suggesting a role for these biomarkers in the underlying mechanism of meditation. Meditation is a simple, organic, and effective way to improve well-being and reduce depression and anxiety.

59 BASIC BIOLOGICAL SCIENCES↗

Ground-based detection of water in Comet Halley

Gaseous water was detected in the coma of comet Halley. Emission was observed in the upsilon 1 + upsilon 3 band at 1.4 microns, and the upsilon 2 + upsilon 3 band at 1.9 microns. Based on the upsilon 1 + upsilon 3 band intensity, the mass loss rate is 2 times 10 to the 29th power molecules/sec (with an uncertainty of a factor of 2) on 29 Oct. 1985, marginally consistent with other detections. The method is applicable to observations of H2O in other fast-moving comets.

Knacke, R. F.↗

A comparison of reconstruction methods for the estimation of coronal mass ejections kinematics based on SECCHI/HI observations

A study of the kinematics and arrival times of coronal mass ejections (CMEs) at Earth, derived from time-elongation maps (J-maps) constructed from STEREO/heliospheric imager (HI) observations, provides an opportunity to understand the heliospheric evolution of CMEs in general. We implement various reconstruction techniques, based on the use of time-elongation profiles of propagating CMEs viewed from single or multiple vantage points, to estimate the dynamics of three geo-effective CMEs. We use the kinematic properties, derived from analysis of the elongation profiles, as inputs to the Drag Based Model for the distance beyond which the CMEs cannot be tracked unambiguously in the J-maps. The ambient solar wind into which these CMEs, which travel with different speeds, are launched, is different. Therefore, these CMEs will evolve differently throughout their journey from the Sun to 1 AU. We associate the CMEs, identified and tracked in the J-maps, with signatures observed in situ near 1 AU by the WIND spacecraft. By deriving the kinematic properties of each CME, using a variety of existing methods, we assess the relative performance of each method for the purpose of space weather forecasting. We discuss the limitations of each method, and identify the major constraints in predicting the arrival time of CMEs near 1 AU using HI observations.

79 ASTRONOMY AND ASTROPHYSICS↗