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At least 1,243 records · Page 69

Exposure to multiple ion beams, broadly representative of galactic cosmic rays, causes perivascular cardiac fibrosis in mature male rats

Long-duration space exploratory missions to the Earth’s moon and the planet Mars are actively being planned. Such missions will require humans to live for prolonged periods beyond low earth orbit where astronauts will be continuously exposed to high energy galactic cosmic rays (GCRs). A major unknown is the potential impact of GCRs on the risks of developing degenerative cardiovascular disease, which is a concern to NASA. A ground-based rat model has been used to provide a detailed characterization of the risk of long-term cardiovascular disease from components of GCRs at radiation doses relevant to future human missions beyond low earth orbit. Six month old male WAG/RijCmcr rats were irradiated at a ground-based charged particle accelerator facility with high energy ion beams broadly representative of GCRs: protons, silicon and iron. Irradiation was given either as a single ion beam or as a combination of three ion beams. For the doses used, the single ion beam studies did not show any significant changes in the known cardiac risk factors and no evidence of cardiovascular disease could be demonstrated. In the three ion beam study, the total cholesterol levels in the circulation increased modestly over the 270 day follow up period, and inflammatory cytokines were also increased, transiently, 30 days after irradiation. Perivascular cardiac collagen content, systolic blood pressure and the number of macrophages found in the kidney and in the heart were each increased 270 days after irradiation with 1.5 Gy of the three ion beam grouping. These findings provide evidence for a cardiac vascular pathology and indicate a possible threshold dose for perivascular cardiac fibrosis and increased systemic systolic blood pressure for complex radiation fields during the 9 month follow up period. The development of perivascular cardiac fibrosis and increased systemic systolic blood pressure occurred at a physical dose of the three ion beam grouping (1.5 Gy) that was much lower than that required to show similar outcomes in earlier studies with the same rat strain exposed to photons. Further studies with longer follow up periods may help determine whether humans exposed to lower, mission-relevant doses of GCRs will develop radiation-induced heart disease.

60 APPLIED LIFE SCIENCES↗

A Magnetized Electron Source For Ion Beam Cooling

A number of electron-ion collider facilities for nuclear physics research are under consid- eration in the United States. At Brookhaven National Lab (BNL), the eRHIC (electron Relativistic Heavy Ion Collider) facility would augment the existing ion/proton facility with an electron accelerator. Thomas Jefferson National Accelerator Facility (JLab) plans to use the existing CEBAF machine and add an ion/proton accelerator, as part of the Jefferson Lab Electron-Ion Collider (JLEIC). All such facilities require cooling of the ion beams in order to reach the luminosity goals. Different methods of cooling the ions using an electron beam are envisaged. BNL is pursuing coherent electron cooling and non-magnetized, bunched-beam cooling, while JLab is considering magnetized cooling. In addition to electron cooling, magnetized beams are of interest for other applica- tions, such as flat beam klystrons and novel means for producing bright beams for micro- undulators and compact X-ray sources. For example, flat beams generated from a mag- netized injector, in conjunction with low emittance, enable RF sources with frequencies above 100 GHz. While the market for high-performance injectors for electron cooling is limited, the market for high-frequency RF sources and compact X-ray systems is con- siderable. Thus, the design methodologies developed in this project have a wide range of applicability. In Phase I of this SBIR project, Xelera Research LLC performed simulations and calcu- lations to develop a prototype design for a magnetized electron injector that can be used as a source for cooling an ion beam. We developed general design methodologies and tech- niques that are applicable not only to specific machine designs but to other applications requiring magnetized injectors as well. In this Phase II SBIR project, Xelera Research LLC, in collaboration with a team at JLab, designed, built, and tested a thermionic elec- tron source for driving a magnetized electron cooler in a future electron-ion collider project. This device was delivered to JLab in July 2019 and achieved first beam in December 2019.

43 PARTICLE ACCELERATORS↗

Microstructural Simulation of Ion-Irradiated Natural Rocks and Minerals

This report details the contribution of Oak Ridge National Laboratory to the Nuclear Energy University Program (NEUP) project, "Rapid Characterization of Concrete Mineralogy using Multi-Scale Tools" led by the University of Illinois at Urbana-Champaign. To support the subsequent license renewal (SLR) of the US nuclear power plants (NPPs) fleet, the performance of concrete-forming aggregates against neutron irradiation needs to be assessed. Ion irradiation is proposed as a rapid, cost-effective surrogate method to full neutron irradiation testing. To complement the characterization of ion-irradiated rock specimens, ORNL has run finite-elements and fast-Fourier transform (FFT-based) simulations using the codes MARS and Microstructure-Oriented Scientific Analysis of Irradiated Concrete (MOSAIC). The main conclusion of this analysis is that the apparent post–ion-irradiation step-height underestimates the accumulated free radiation-induced volumetric expansion (RIVE) in the ion-implanted depth by about 15% at full amorphization and about 25% toward the beginning of the ion irradiation experiment. The discrepancy is explained by the fact that the step height is proportional to the sum of the RIVE (i.e., one third of the RIVE) and the irradiation-assisted plastic strains in the vertical direction (lower than two thirds of the RIVE). Because of the large lateral compressive stresses caused by the restraining effect of the unirradiated substrate, the stress field in the mineral grains and at the grain boundary (GB) in the ion-implanted layer is much different than the comparable stress field occurring during neutron irradiation. Hence, the mismatch RIVE causing cracks in the rock-forming minerals leads to different cracking patterns. Ion irradiation continues to be used as a rapid technique to assess the RIVE potential of rocks.

11 NUCLEAR FUEL CYCLE AND FUEL MATERIALS↗

Species mix & distribution function dependence of energetic-ion driven magnetospheric instabilities on DIII-D (Final Report)

Energetic ions drive a rich variety of instabilities in the complex multi-species plasma of Earth’s magnetosphere. This experiment exploited the highly flexible, high power particle beam injection capability and sophisticated diagnostic suite of the DIII-D tokamak to advance understanding of two particular instabilities of significant interest to the magnetospheric research community that have closely-related counterparts in beam-heated tokamak plasmas: electromagnetic ion cyclotron waves (EMIC) [1], observed at frequencies somewhat below the ion cyclotron frequencies of bulk ion species, and equatorial noise [2], observed at energetic-ion cyclotron harmonics. In the magnetic fusion energy domain, such waves are called ICE (Ion Cyclotron Emission). Recent substantial advances in diagnostic capability in the ion cyclotron range of frequencies in DIII-D, including measurement of wave polarization, spa)al structure and amplitude created an exciting opportunity to challenge and drive advances in theoretical understanding of these phenomena.

70 PLASMA PHYSICS AND FUSION TECHNOLOGY↗

Enabling Ultralow Volume Analysis with a High-Resolution Ion Mobility Mass Spectrometry Platform

Of all the molecules thought to exist in the universe, it is estimated that researchers only know the chemical structures of 5% of them. Identifying the chemical structures of the remaining 95% has proven extremely challenging because many molecules exhibit low abundance, are contained in small volumes (e.g., <10 nL), do not readily ionize, exhibit similar structures to other molecules, etc. No single analytical technique exists to definitively identify the structure of an unknown molecule, and thus multiple different molecular measurements are typically made (i.e., multi-modal approach). Ion mobility (IMS) and mass spectrometry (MS) are two key tools that researchers use to determine the chemical structures of unknown molecules, and recently high-resolution and ultrahigh resolution IMS-MS instruments have provided greater confidence than ever before. However, HR-IMS-MS instruments typically exhibit low ion utilization efficiency, meaning they require large amounts of sample for an analysis (e.g., >10 µL). Unfortunately, this limitation prohibits the analysis of small volume samples where many unknown molecules exist. Described herein are the efforts made to enable the analysis of ultralow volumes with an HR-IMS-MS platform. A new scanning technique, termed a ‘stuttered traveling wave scan’, was developed as a replacement for the dual-gated scanning technique and works by halting the traveling waves after allowing ions to separate and then repeatedly restarting and stopping the traveling waves to incrementally move ions from the SLIM to the Orbitrap. Ions were stored inside the SLIM while the TWs were stopped, allowing the Orbitrap to perform high-resolution mass analysis. When the Orbitrap was ready, the TWs were restarted for short periods of time (<10 ms) to move ions from the SLIM to the Orbitrap. It was discovered that lower TW amplitudes and speeds than used during IMS separation were required to produce IMS peaks with the highest signal intensities and best resolving powers. The stuttered TW scan was found to produce similar resolutions and signal intensities compared to the dual-gated scanning technique. A new IMS design possessing an intersecting ‘tee’ with a reversible traveling wave was also developed to improve ion utilization efficiency during cyclic operation, which is necessary when only a single IMS spectrum can be acquired, such as when analyzing ultralow volume samples. The new capabilities described in this report lay the groundwork for acquiring HR-IMS-MS spectra of ultralow volume biological samples, such as single cells, where HR-IMS-MS can help elucidate the structures of unknown compounds.

37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CH↗

SIREN: Scaling Ion-Traps by REquiring iNnovative Heterogenous Integration

The SIREN (Scaling Ion Traps by Requiring iNnovative heterogenous integration) project explores the feasibility of heterogeneous integration (HI) as a transformative approach to scaling ion traps, a critical technology for advancing quantum computers and atomic clocks. Traditional ion trap architectures face significant challenges in scalability due to limitations in optical access, fabrication techniques, and material constraints. SIREN addresses these challenges by leveraging HI, which combines different materials and fabrication processes to create more complex and efficient ion trap structures. HI integrated structures can be manufactured without compromising the process to maintain compatibility to ion traps. This project focuses on integrating a separately fabricated waveguide with a fully functional ion trap. The respective alignment between the pieces needs to be accurate to less than 2 µm to ensure that the light from the waveguide can overlap with the trapping region. The fine alignment must also be maintained through an ultra-high vacuum bake, a critical step in preparing an ion trap experiment. The project's outcomes suggest that heterogeneous integration is a promising pathway for overcoming current scalability barriers, paving the way for the next generation of quantum technologies. SIREN's findings contribute significantly to the field, offering a scalable solution that could accelerate the development of practical quantum computers and highly accurate atomic clocks.

42 ENGINEERING↗

Fast-ion confinement in LHD and W7-X (Final Technical Report)

This project was the PhD thesis project for Wataru Hayashi, who graduated in December 2025. In work performed prior to the award while Heidbrink was a Guest Professor at NIFS, we had established conditions for the study of fast-ion confinement in the Large Helical Device (LHD) with fast-ion D-alpha (FIDA) diagnostics. Subsequently, we proposed new sightlines that could augment the existing FIDA measurements with ones that were more sensitive to the highest energy ions. During the project period, the new sightlines were installed by the LHD team and showed the expected enhanced sensitivity to high-energy ions. Many LHD experiments were led by UCI scientists remotely during the pandemic and in-person afterward. One of these, which was led by one of Professor Zhihong Lin’s PhD students (Ethan Green) in collaboration with Hayashi and Heidbrink, resulted in a Nuclear Fusion article on the effect of radial electric fields on fast-ion confinement. The main output of the project, however, is two detailed experimental papers by Hayashi et al. The first of these is a study of neoclassical fast ion confinement in MHD-quiescent plasmas, a key issue in stellarator research. The second is an initial study of the effect of Alfven eigenmodes on fast-ion confinement. In addition to these studies, the project also helped partially support stellarator research with the GTC code by members of Prof. Lin’s group.

70 PLASMA PHYSICS AND FUSION TECHNOLOGY↗

Chemical identification of new particle formation and growth precursors through positive matrix factorization of ambient ion measurements

Abstract. In the lower troposphere, rapid collisions between ions and trace gases result in the transfer of positive charge to the highest proton affinity species and negative charge to the lowest proton affinity species. Measurements of the chemical composition of ambient ions thus provide direct insight into the most acidic and basic trace gases and their ion–molecule clusters – compounds thought to be important for new particle formation and growth. We deployed an atmospheric pressure interface time-of-flight mass spectrometer (APi-ToF) to measure ambient ion chemical composition during the 2016 Holistic Interactions of Shallow Clouds, Aerosols, and Land Ecosystems (HI-SCALE) campaign at the United States Department of Energy Atmospheric Radiation Measurement facility in the Southern Great Plains (SGP), an agricultural region. Cations and anions were measured for alternating periods of ∼ 24 h over 1 month. We use binned positive matrix factorization (binPMF) and generalized Kendrick analysis (GKA) to obtain information about the chemical formulas and temporal variation in ionic composition without the need for averaging over a long timescale or a priori high-resolution peak fitting. Negative ions consist of strong acids including sulfuric and nitric acid, organosulfates, and clusters of NO3- with highly oxygenated organic molecules (HOMs) derived from monoterpene (MT) and sesquiterpene (SQT) oxidation. Organonitrates derived from SQTs account for most of the HOM signal. Combined with the diel profiles and back trajectory analysis, these results suggest that NO3 radical chemistry is active at this site. SQT oxidation products likely contribute to particle growth at the SGP site. The positive ions consist of bases including alkyl pyridines and amines and a series of high-mass species. Nearly all the positive ions contained only one nitrogen atom and in general support ammonia and amines as being the dominant bases that could participate in new particle formation. Overall, this work demonstrates how APi-ToF measurements combined with binPMF analysis can provide insight into the temporal evolution of compounds important for new particle formation and growth.

37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CH↗

Gadolinium-hydrogen ion exchange of zirconium phosphate

The Gd(+3)/H(+) ion exchange on a commercial zirconium phosphate ion exchanger was investigated in chloride, sulfate, and phosphate solutions of Gd(+3) at gadolinium concentrations of 0.001 to 1 millimole per cc and in the pH range of 0 to 3.5. Relatively low Gd(+3) capacities, in the range of 0.01 to 0.1 millimole per g of ion exchanger were found at room temperature. A significant difference in Gd(+3) sorption was observed, depending on whether the ion exchanger was converted from initial conditions of greater or lesser Gd(+3) sorption than the specific final conditions. Correlations were found between decrease in Gd(+3) capacity and loss of exchanger phosphate groups due to hydrolysis during washing and between increase in capacity and treatment with H3PO4. Fitting of the experimental data to ideal ion exchange equilibrium expressions indicated that each Gd(+3) ion is sorbed on only one site of the ion exchanger. The selectivity quotient was determined to be 2.5 + or - 0.4 at room temperature on gadolinium desorption in chloride solutions.

Liu, D. C.↗

Ion heating mechanism in a modified Penning discharge

Ions with Maxwellian energy distributions and kinetic temperatures ranging from 20 eV to 7 keV have been observed in a modified Penning discharge operating in the steady state. Investigation of the plasma revealed two distinct spoke-like concentrations of charge rotating with different velocities in the sheath between the plasma and the anode ring. The faster spoke consists of electrons rotating with the E/B drift velocity, where E is the electric field and B is the magnetic field strength. The slow spoke consists of ions, the thermal velocity of which is observed to be proportional to the spoke velocity. The experimental data are consistent with a model whereby the ion drift velocity in this spoke, corresponding to kilovolt ion energies, is Maxwellianized by strong electrostatic turbulence in the sheath. Theoretical expressions are derived for the frequency of the electron and ion spoke rotation, for the ion kinetic temperature, and for the ion heating efficiency as functions of the discharge parameters. These expressions are shown to be consistent with extensive experimental data.

Roth, J. R.↗

Suprathermal ions near the moon.

This paper reports some preliminary results from the suprathermal ion detectors deployed on the lunar surface by the Apollo 12 and 14 astronauts. Salient features of these results include: the possible observation of sporadic venting of gas from the lunar surface; evidence for a prompt ionization and acceleration mechanism operating in the lunar exosphere; and a preliminary measurement yielding approximately 1 month for the e-folding decay time for the heavier components of the exhaust gases from the Apollo lunar landing systems. Prominent phenomena from which these results have been derived are: (1) ion bursts of low to moderate energy seen in conjunction with lunar sunrise and sunset; (2) solar wind energy ions detected on the night side of the moon; (3) ions of several keV energy seen during the lunar sunset to midnight quadrant of the moon's orbit; (4) magnetosheath ion flux enhancements; (5) ion bursts generated by the lunar impact of the Apollo 13 Saturn upper stage; and (6) geomagnetic storm associated ion flux variations in the earth's magnetotail.

Freeman, J. W., Jr.↗

Molecular ions in the F2 layer.

Data on ion concentrations at heights of 400-500 km, obtained by the OGO VI satellite, suggest that the O(+) and molecular ion concentrations are sometimes anticorrelated. To assist in explaining this phenomenon, a table of the chemical reactions most likely to control the molecular ion concentrations is drawn up, and its validity tested with the aid of data from rocket-borne mass spectrometers at heights of 220-400 km. The anticorrelation of O(+) and NO(+) ions by day is thought to be due to the importance of a reaction between N2(+) ions and O atoms; the main source of N2(+) above 300 km is probably charge-exchange between N2 and O(+), the latter being produced by photoionization. However, at night another source of NO(+) ions is required, which may be N(+) ions that are either stored in the magnetosphere or are produced from He(+) and N2.

Rishbeth, H.↗

The light ion trough, the main trough, and the plasmapause

Extensive observations of mid-latitude depletions in electron and total ion density by both direct and indirect techniques, have prompted numerous studies of the possible association between these troughs, observed in the F-region, the topside ionosphere, and the plasmapause. One basic problem arises, in that while the plasmapause was detected as a global phenomenon both by VLF and ion composition measurements, the electron and ion density troughs were identified primarily as nightside features. This problem, as well as the difficulty in explaining various inconsistencies in relating the position of the plasmapause and the ionization trough, is explained by a close examination of the ion composition. In particular, ion composition results from the polar orbiting OGO satellites identify the persistence of a pronounced light ion trough in H(+) and He(+) identified by order of magnitude decreases in the light ion concentrations.

Taylor, H. A., Jr.↗

Measurements of recombination of electrons with H3(plus) and H5(plus) ions

The electron-ion recombination coefficients for H3(+) and H5(+) ions were determined by means of a microwave afterglow/mass spectrometer apparatus. Measurements of electron density decays in helium-hydrogen mixtures are correlated with the decay of mass-identified ion currents to the wall of the microwave cavity. At low partial pressures of hydrogen in the mixture, the ion H3(+) dominates the ion composition and the ion wall current tracks the electron density decay curves. From recombination controlled electron density decay curves, the values alpha (H3(+)) = (2.9 + or - 0.3), (2.3 + or - 0.3), and (2.0 + or - 0.2) x 0.0000001 cu cm per sec, are obtained at 205, 300 and 450 K, respectively. At higher partial pressures of hydrogen and low temperatures, where (H5(+)) is the dominant ion, the value alpha (H5(+)) = (3.6 + or - 1.0) x 0.0000001 cu cm per sec is obtained at 205 K. The implications of these results concerning ionization levels in the atmospheres of the outer planets and in the interstellar medium are discussed.

Leu, M. T.↗

Acceleration of heavy ions by radiation pressure.

The possible acceleration of heavy ions by the resonance scattering of radiation near bright stellar objects is examined. Planck spectra are assumed. At any radiation temperature, heavy-ion energies are found to be limited by aberration and Doppler effects. Photoionization is found to limit maximum radiation temperatures and energies for each ion. Collisional ionization by ambient electrons and ions may further limit heavy-ion energies. Because of these limitations, the production of the more energetic cosmic rays by this mechanism appears to be very improbable. If supernova radiation temperatures are high enough, they may produce heavy ions with energies up to several hundreds of MeV per nucleon. O and B stars appear to be able to accelerate certain heavy ions to 200 and 80 MeV per nucleon, respectively.

Nakada, M. P.↗

Hot ion plasma heating experiments in SUMMA

Initial results are presented for the hot-ion plasma heating experiments conducted in the new SUMMA (superconducting magnetic mirror apparatus) at NASA Lewis Research Center. A discharge is formed by applying a radially inward dc electric field between cylindrical anodes and hallow cathodes located at the peak of the mirrors. Data were obtained at midplane magnetic field strengths from 1.0 to 3.5 tesla. Charge-exchange neutral particle energy analyzer data were reduced to ion temperatures using a plasma model that included a Maxwellian energy distribution superimposed on an azimuthal drift, finite ion orbits, and radial variations in density and electric field. The best ion temperatures in a helium plasma were 5 keV and in hydrogen the H2(+) and H(+) ions were 1.2 keV and 1 keV respectively. Optical spectroscopy line broadening measurements yielded ion temperatures about 50 percent higher than the charge-exchange neutral particle analyzer results. Spectroscopically obtained electron temperature ranged from 3 to 30 eV. Ion temperature was found to scale roughly linearly with the ratio of power input-to-magnetic field strength, P/B.

Reinmann, J. J.↗

Observation of a two-temperature ion energy distribution in regions of polar wind flow

Study of deviations from thermal equilibrium among the ions in the ionosphere by considering that the 'light' ions H(+) and He(+) may be at a different temperature from the 'heavy' ion O(+). In particular, the case in which thermal protons are observed to be flowing relative to the assumed static ambient oxygen ions is considered. The proton flow is assumed to be along the direction of the magnetic field. Of the cases tested, it is found that the measured proton temperature is from one to ten times the measured oxygen ion temperature. Such temperature enhancements may be expected both because of the energy transfer associated with the ion flow and as a consequence of the preferential energy coupling from the light-ion distribution in the exosphere.

Maier, E. J.↗

The ion-optics of a two-grid electron-bombardment thruster

A detailed experimental investigation was performed to determine the ion-optical performance of an electron-bombardment ion thruster as a function of grid geometry changes. The results show that each geometrical grid parameter independently affects one aspect of ion-optical performance. These observations are used in developing a graphical technique to predict the ion-optical performance of an arbitrary ion source and grid geometry combination. The usefulness of this technique is demonstrated by comparing predicted ion-optical performance of the 30-cm diameter engineering model ion thruster with independent experimental determinations. Good agreement is shown between predicted and experimental results.

Aston, G.↗