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Design and Testing of an Approach to Automated In-Flight Safety Risk Management for sUAS Operations
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Firex Water Tank, SWMU 069, Confirmatory Sampling Report
The National Aeronautics and Space Administration (NASA) Resource Conservation and Recovery Act (RCRA) permit requires identification and evaluation of known Solid Waste Management Units (SWMU) located at the Kennedy Space Center (KSC). Firex Water Tank (FWT), or the “site,” is designated as SWMU 069 under the NASA RCRA permit. This report summarizes the results of the Confirmatory Sampling (CS) field activities carried out during Fall 2021, at FWT, SWMU 069, KSC, Florida. Three locations of concern (LOCs) were identified by screening historical sample results to current State of Florida soil cleanup target levels (SCTL). A total of 18 soil samples were collected to investigate the historical exceedance locations. Samples at LOC 1 and 2 were analyzed for arsenic and the results for all were below the SCTL. Samples at LOC 3 were analyzed for polynuclear aromatic hydrocarbons and it was determined that certain locations have results that remain above the SCTL. The current land use controls will remain in place at FWT to mitigate potential risks.
Genomic and Phenotypic Associations to Predict Human Sensitivity to SpaceRadiation
High-linear energy transfer (LET) ionizing radiation is a major health hazard for astronauts who will be exposed to galactic cosmic rays during upcoming lunar and Mars missions. Predicting and mitigating this risk requires understanding the factors underlying individual radiation sensitivity. We started to address this challenge by identifying the genomic and phenotypic associations with sensitivity to low and high-LET ionizing radiation ex vivo in over 750 healthy human donors. We exposed primary human blood mononuclear cells to simulated galactic cosmic ray components: 350MeV/n 28Si, 350MeV/n 40Ar and 600MeV/n 56Fe particles, at 1.1 and 3 particles/100 sq.m fluences, as well as 0.1 Gy and 1 Gy doses of gamma rays, and analyzed the outcomes at 4 and 24 hours post-irradiation. We quantified DNA damage and repair responses based on 53BP1+ radiation-induced foci formation, together with oxidative stress and changes in secreted factors including immune cytokines and exosomes. We also analyzed phenotypic associations with spontaneous DNA repair foci at baseline prior to irradiation. We identified an increase in spontaneous DNA repair associated with age and latent viral infection, and observed that human spontaneous DNA repair foci at baseline can serve as a negative predictor of DNA repair and immunoregulatory cytokine production after irradiation. Furthermore, we observed a wide variability of subject- and LET-dependent radiation responses, with radiation-induced DNA repair foci increasing by dose and LET, and high-LET particle radiation resulting in more residual DNA damage compared to low-LET particles and gamma rays. We have developed multiple metrics to quantify human radio sensitivity across the spectrum of conditions. Here we present their dependence on radiation quality and phenotypic variables, including an age-dependent decrease in DNA repair after irradiation, and genomic associations with radio sensitivity based on low-coverage whole genome sequencing. We anticipate that our work will pave the way for understanding the spectrum of human radio sensitivity and identifying targets for countermeasure development to reduce DNA and cellular damage and radiation carcinogenesis during deep space exploration.
Genomic and Phenotypic Predictors of Human Ex Vivo Sensitivity to Simulated Deep Space Radiation
High-linear energy transfer (LET) ionizing radiation is a major health hazard for astronauts who will be exposed to galactic cosmic rays during upcoming lunar and Mars missions. Predicting and mitigating this risk requires understanding the factors underlying individual radiation sensitivity. We started to address this challenge by identifying the genomic and phenotypic associations with sensitivity to low and high-LET ionizing radiation ex vivo in over 750 healthy human donors. We exposed primary human blood mononuclear cells to simulated galactic cosmic ray components: 350 MeV/n 28Si, 350 MeV/n 40Ar and 600 MeV/n 56Fe particles, at 1.1 and 3 particles/100 sq.m fluences, as well as 0.1 Gy and 1 Gy doses of gamma rays, and analyzed the outcomes at 4 and 24 hours post-irradiation. We quantified DNA damage and repair responses based on 53BP1+ radiation-induced foci formation, together with oxidative stress and changes in secreted factors including immune cytokines and exosomes. We also analyzed phenotypic associations with spontaneous DNA repair foci at baseline prior to irradiation. We identified an increase in spontaneous DNA repair associated with age and latent viral infection, and observed that human spontaneous DNA repair foci at baseline can serve as a negative predictor of DNA repair and immunoregulatory cytokine production after irradiation. Furthermore, we observed a wide variability of subject- and LET-dependent radiation responses, with radiation-induced DNA repair foci increasing by dose and LET, and high-LET particle radiation resulting in more residual DNA damage compared to low-LET particles and gamma rays. We have developed multiple metrics to quantify human radiosensitivity across the spectrum of conditions. Here we present their dependence on radiation quality and phenotypic variables, including an age-dependent decrease in DNA repair after irradiation, and genomic associations with radiosensitivity based on low-coverage whole genome sequencing. We anticipate that our work will pave the way for understanding the spectrum of human radiosensitivity and identifying targets for countermeasure development to reduce DNA and cellular damage and radiation carcinogenesis during deep space exploration.
Firex Water Tank, SWMU 069, Confirmatory Sampling Report: Revision 2
The National Aeronautics and Space Administration (NASA) Resource Conservation and Recovery Act (RCRA) permit requires identification and evaluation of known Solid Waste Management Units (SWMU) located at the Kennedy Space Center (KSC). Firex Water Tank (FWT), or the “site,” is designated as SWMU 069 under the NASA RCRA permit. This report summarizes the results of the Confirmatory Sampling (CS) field activities carried out during Fall 2021, at FWT, SWMU 069, KSC, Florida. Three locations of concern (LOCs) were identified by screening historical sample results to current State of Florida soil cleanup target levels (SCTL). A total of 18 soil samples were collected to investigate the historical exceedance locations. Samples at LOC 1 and 2 were analyzed for arsenic and the results for all were below the SCTL. Samples at LOC 3 were analyzed for polynuclear aromatic hydrocarbons and it was determined that certain locations have results that remain above the SCTL. The current land use controls will remain in place at FWT to mitigate potential risks.
Genomic and phenotypic predictors of human ex vivo sensitivity to simulated deep space radiation
High-linear energy transfer (LET) ionizing radiation is a major health hazard for astronauts who will be exposed to galactic cosmic rays during upcoming lunar and Mars missions. Predicting and mitigating this risk requires understanding the factors underlying individual radiation sensitivity. We started to address this challenge by identifying the genomic and phenotypic associations with sensitivity to low and high-LET ionizing radiation ex vivo in over 750 healthy human donors. We exposed primary human blood mononuclear cells to simulated galactic cosmic ray components: 350MeV/n (28)Si, 350MeV/n (40)Ar and 600MeV/n (56)Fe particles, at 1.1 and 3 particles/100µm^(2) fluences, as well as 0.1 Gy and 1 Gy doses of gamma rays, and analyzed the outcomes at 4 and 24 hours post-irradiation. We quantified DNA damage and repair responses based on 53BP1^(+) radiation-induced foci formation, together with oxidative stress and changes in secreted factors including immune cytokines and exosomes. We also analyzed phenotypic associations with spontaneous DNA repair foci at baseline prior to irradiation. We identified an increase in spontaneous DNA repair associated with age and latent viral infection, and observed that human spontaneous DNA repair foci at baseline can serve as a negative predictor of DNA repair and immunoregulatory cytokine production after irradiation. Furthermore, we observed a wide variability of subject- and LET-dependent radiation responses, with radiation-induced DNA repair foci increasing by dose and LET, and high-LET particle radiation resulting in more residual DNA damage compared to low-LET particles and gamma rays. We have developed multiple metrics to quantify human radiosensitivity across the spectrum of conditions. Here we present their dependence on radiation quality and phenotypic variables, including an age-dependent decrease in DNA repair after irradiation, and genomic associations with radiosensitivity based on low-coverage whole genome sequencing. We anticipate that our work will pave the way for understanding the spectrum of human radiosensitivity and identifying targets for countermeasure development to reduce DNA and cellular damage and radiation carcinogenesis during deep space exploration.
Innovative IO Psychology Research for Future Space Exploration
Crewed space exploration is evolving. The commercialization of space includes Private Astronauts who interact with NASA astronauts on the International Space Station. Astronauts are scheduled to complete a variety of tasks within a fast paced timeline. Future exploration missions to Mars will include challenges such as a small crew living and working in an isolated and confined environment for up to 2 ½ years, with significant communication delays from Earth. This symposium brings together four innovative studies designed to mitigate the risks associated with space flight.
Gateway at the Crossroads of Sustainable Lunar Exploration
The Gateway Program has made substantial design and development progress toward delivering a small, human-tended lunar space station purposefully designed to enable sustainable human exploration. The Program integrates partners and providers organizationally and physically as part of the spacecraft. The Power and Propulsion Element (PPE) and the Habitation and Logistics Outpost (HALO) with the European System Providing Refueling, Infrastructure and Telecommunications (ESPRIT) HALO Lunar Communications System (HLCS) have begun manufacturing the long lead components and will be launched first as a Co-Manifested Vehicle (CMV). The International Habitat (I-Hab) and ESPRIT Refueling Module (ERM) are passing life cycle milestones and include capabilities key for human crewmembers, such as windows, private sleeping quarters, and galley functions. The Logistics Module (LM) may provide a variety of services to Gateway depending on each mission. Requirements for the airlock have been developed, including requests that it support the integrated spacecraft with functions like augmenting heat rejection capabilities, and interfaces with new spacesuits will soon be developed in more detail. As a critical element of the architecture for solar system exploration, Gateway implements key tenets and features of international interoperability standards necessary to operate with multiple visiting vehicles and lunar assets, especially avionics, communications, and docking. Specific choices such as software architecture and standards, power standards, and robotics standards make it possible to utilize heritage or proprietary technology, yet still operate as one spacecraft. Engineering teams are evaluating many possible future missions to be executed at or utilizing the Gateway. The system architecture protects for an evolvable, extensible, and flexible capability. Designing systems robust enough to serve as a cornerstone of exploration activities for decades while remaining adaptable is not without its challenges. The detailed integration activities have revealed challenges and the need to mature key technologies. Refueling is a key component of achieving long life for Gateway, with unique operations to plan, safety concerns to mitigate, and risk reduction activities to conduct to better understand the system. The constraints and impacts of the design of visiting vehicles is also an important concern, with orientation constraints, control of attitude and orbit of the Gateway with docked visiting vehicles. Tradeoffs between robust maintainable systems and lightweight, compact systems must be balanced. Opportunities still exist for adding additional advanced capabilities to increase and extend Gateway’s benefits, such as intravehicular robotics, autonomous Guidance Navigation and Control (GN&C), and augmented control propulsion, heat rejection, or other services.
Global Assessment of the Capability of Satellite Precipitation Products to Retrieve Landslide-Triggering Extreme Rainfall Events
Rainfall-induced landsliding is a global and systemic hazard that is likely to increase with the projections of increased frequency of extreme precipitation with current climate change. However, our ability to understand and mitigate landslide risk is strongly limited by the availability of relevant rainfall measurements in many landslide prone areas. In the last decade, global satellite multisensor precipitation products (SMPP) have been proposed as a solution, but very few studies have assessed their ability to adequately characterize rainfall events triggering landsliding. Here, we address this issue by testing the rainfall pattern retrieved by two SMPPs (IMERG and GSMaP) and one hybrid product [Multi-Source Weighted-Ensemble Precipitation (MSWEP)] against a large, global database of 20 comprehensive landslide inventories associated with well-identified storm events. We found that, after converting total rainfall amounts to an anomaly relative to the 10-yr return rainfall R*, the three products do retrieve the largest anomaly (of the last 20 years) during the major landslide event for many cases. However, the degree of spatial collocation of R* and landsliding varies from case to case and across products, and we often retrieved R* > 1 in years without reported landsliding. In addition, the few (four) landslide events caused by short and localized storms are most often undetected. We also show that, in at least five cases, the SMPP’s spatial pattern of rainfall anomaly matches landsliding less well than does ground-based radar rainfall pattern or lightning maps, underlining the limited accuracy of the SMPPs. We conclude on some potential avenues to improve SMPPs’ retrieval and their relation to landsliding.
Design and Development of an Aircraft Electric Powertrain Test Stand
Recent advancements in battery technology and power electronics are enabling novel approaches to powered flight that rely on fully electric or hybrid-electric powertrain systems. To mitigate the risk surrounding such unproven systems, it is necessary to characterize their performance on a component-wide and system-wide basis. In this paper, we discuss the design and development of an electric powertrain test stand that can collect high-fidelity data of motor, controller, and battery performance, thereby allowing us to determine system performance, efficiencies, and thermal characteristics.
Palmer Station, Antarctica: A Ground-Based Spaceflight Analog Suitable for Validation of Biomedical Countermeasures for Deep Space Missions
Astronauts are known to exhibit a variety of immunological alterations during spaceflight including changes in leukocyte distribution and plasma cytokine concentrations, a reduction in T-cell function, and subclinical reactivation of latent herpesviruses. These alterations are most likely due to mission-associated stressors including circadian misalignment, microgravity, isolation, altered nutrition, and increased exposure to cosmic radiation. Some of these stressors may also occur in terrestrial situations. This study sought to determine if crewmembers performing overwinter deployment at Palmer Station, Antarctica displayed similar immune alterations. The larger goal was to validate a ground analog suitable for the evaluation of countermeasures designed to protect astronauts during future deep space missions. For this pilot study, plasma, saliva, hair, and health surveys were collected from Palmer Station, Antarctica winterover participants at baseline, and at five overwinter timepoints. Twenty-six subjects consented to participate over the course of two seasons. Initial sample processing was performed at Palmer, and eventually stabilized samples were returned to the Johnson Space Center for analysis. A white blood cell differential was performed (real time) using a fingerstick blood sample to determine alterations in basic leukocyte subsets throughout the winterover. Plasma and saliva samples were analyzed for 30 and 13 cytokines, respectively. Saliva was analyzed for cortisol concentration and three latent herpesviruses (DNA by qPCR), EBV, HSV1, and VZV. Hair samples were analyzed for several hormones, as a measure of stress over prolonged periods of time. Voluntary surveys related to general health and adverse clinical events were distributed to participants. It is noteworthy that due to logistical constraints due to COVID-19, the baseline samples for each season were collected in Punta Arenas, Chile, after long international travel and during isolation. Therefore, the palmer pre mission samples may not reflect a true normal ‘baseline’. Minimal alterations were observed in leukocyte distribution during overwinter. The mean percentage of monocyte concentration elevated at one timepoint. Plasma G-CSF, IL1RA, MCP-1, MIP-1β, TNFα and VEGF were decreased during at least one overwinter timepoint, whereas RANTES was significantly increased. No statistically significant changes were observed in mean saliva cytokine concentrations. Salivary cortisol was substantially elevated throughout the entire winterover compared to baseline. Compared to shedding levels observed in healthy controls (23%), the percentage of participants who shed EBV was higher throughout all winterover timepoints (52-60%). Five subjects shed HSV1 during at least one timepoint throughout the season compared to no subjects shedding during pre-deployment. Finally, VZV reactivation, common in astronauts but exceptionally rare in ground-based stress analogs, was observed in one subject during pre-deployment and a different subject at WO2 and WO3. These pilot data, somewhat influenced by the COVID-19 situation, do suggest that participants at Palmer Station do undergo immunological alterations similar to, but likely in reduced magnitude, as those observed in astronauts. We suggest that overwinter at Palmer Station may be suitable test analog for spaceflight biomedical countermeasures designed to mitigate clinical risks for deep space missions.
Is "Sleepy Supervision" the New "Drowsy Driving"?
Human error has been implicated as a causal factor in a large proportion of road accidents. Automated driving systems purport to mitigate this risk, but self-driving systems that allow a driver to entirely disengage from the driving task also require the driver to monitor the environment and take control when necessary. Given that sleep loss impairs monitoring performance and there is a high prevalence of sleep deficiency in modern society, we hypothesized that supervising a self-driving vehicle would unmask latent sleepiness compared to manually controlled driving among individuals following their typical sleep schedules. We found that participants felt sleepier, had more involuntary transitions to sleep, had slower reaction times and more attentional failures, and showed substantial modifications in brain synchronization during and following an autonomous drive compared to a manually controlled drive. Our findings suggest that the introduction of partial self-driving capabilities in vehicles has the potential to paradoxically increase accident risk.
Aviation 2072: Scenario Planning for Wicked Problems
The world is changing rapidly. And with it, so are the potential futures for humanity. Many of these potential futures pose hidden threats, while others offer new opportunities for aviation and the broader aerospace community. To mitigate these risks and capitalize on opportunities, organizations must work to deeply understand these potential future scenarios and uncover any underlying drivers. Organizations will be more equipped and informed when making strategic investment decisions by better understanding these threats, opportunities, and drivers . The future scenarios and their threats and opportunities described in this paper were identified through a series of extensive brainstorming workshops, collectively titled MADNESS (Mapping for Aviation Driven by Needs Emergence and Satiating Society). These workshops engaged NASA civil servants and contractors with diverse backgrounds through a facilitated process of future scenario development and critique. The participants were led through exercises focused on a time horizon spanning from 2022 to 2072 and on problems that aviation might solve and or create during this period. From the broad results, two patterns of critical uncertainty emerged: “availability” (scarcity versus abundance) and “transparency” (openness versus security and privacy). The successful iteration and ideation across the MADNESS workshops also suggests a repeatable mechanism for strategic risk exploration across a variety of NASA and industry stakeholders.
Critical Current Stability of 2G REBCO Tape for Space-Flight HTS Leads
High reliability is an essential requirement for all spaceflight hardware. XRISM, a follow-on mission to the Hitomi x-ray observatory, also uses 2G REBCO tapes as current leads for the superconducting magnets that are a key component of the Adiabatic Demagnetization Refrigerator (ADR) that cools the detector array. While the Hitomi Soft X-ray Spectrometer (SXS) worked flawlessly in orbit, during its development there were indications that the critical current of its specialized REBCO tapes could degrade over time when exposed to normal-humidity air. To demonstrate that the updates to the XRISM HTS lead assemblies had mitigated this risk, a series of tests were carried out to measure the stability of Ic of dozens of samples over a period greater than the flight assemblies were exposed to air during integration and test. The test rig allowed not only the measurement of the sample Ic, but also the localization of the voltage rise as the current approached Ic. We will discuss the trends in the critical current of the samples, as well as localization of lower Ic regions.
NASA’s Role in Putting Earth Science Information to Use in Decision-Making
The demand for decision-relevant climate information is continually growing, both because of the severity and intensity of climate change impacts and because of the growing recognition that people can take actions today that will mitigate the risk from future climate impacts. Agencies across the federal government are responding to this need by working together to support the Nation in becoming more resilient to climate change. NASA Earth Science has been a key engine of understanding global climate change and how it impacts people around the world. Additionally, for over two decades, the Agency has worked, via partnerships, to connect NASA Earth Science knowledge with decision support needs, often taking a service-oriented approach by working with boundary organizations and climate service providers. In this presentation, we describe NASA’s unique role in enabling new and practical uses of Earth science information, and how the Agency supports public and private sector partners. We highlight several key examples of NASA projects and activities that support local to regional climate resilience efforts. In addition, we discuss how NASA’s new Earth Information Center, a partnership among several federal agencies, enables in-person and virtual visitors to see how our planet is changing in ways that affect their lives and livelihoods. Lastly, we discuss plans for how NASA Earth Science will continue to help build a more climate resilient future.
Logistics Rates and Assumptions for Future Human Spaceflight Missions Beyond LEO
As NASA prepares for future human spaceflight missions with extended crew duration in destinations beyond low Earth orbit (LEO), the Agency has focused itself on understanding the drivers to sustainably support human life beyond Earth’s atmosphere. Future missions to deep space, the lunar surface, and eventually the Martian surface pose new challenges in ensuring the crew is sufficiently supplied with all necessary materials. To mitigate the risk of not delivering sufficient consumables and logistics for human spaceflight missions, NASA has examined past human space mission data and developed metabolic modeling to determine estimates for the crew consumption rates of fluids, solid consumables, and additional equipment needed. This paper is a compilation of guidelines, rates, and assumptions necessary to evaluate the logistics needs for future human exploration conceptual missions beyond LEO, providing a starting point and resource of information regarding usage rates and overall logistics supply planning for crewed exploration missions. Logistics represent all equipment and supplies not installed as part of the vehicle that are needed to support mission activities. Logistics can be further divided into specific categories, including consumables, maintenance items, spares, utilization, outfitting, as well as any packaging required. This paper will also provide use case examples of logistics needs to support human missions in deep space, including a conceptual lunar surface mission. The paper provides information necessary to calculate the mass and volume of known logistics for conceptual future human exploration missions beyond LEO. The assumptions in the paper are updated versions of previous assumptions made by the Agency and were derived from a number of sources, including International Space Station (ISS) historical usage and resupply rates, the Life Support Baseline Values and Assumptions Document (BVAD) 2022, Human Integration Design Handbook (HIDH) 2014, and data gathered from NASA human spaceflight programs and projects. The primary goal of the paper is to establish a set of consistent reference rates that multiple teams and groups can utilize to conduct logistics analysis and compare cases. This methodology is for initial estimates of conceptual human missions and does not take the place of detailed analysis for programs, nor does it provide requirements for programs.
Gateway at the Crossroads of Sustainable Lunar Exploration
The Gateway Program has made substantial design and development progress toward delivering a small, human-tended lunar space station purposefully designed to enable sustainable human exploration. The Program integrates partners and providers organizationally and physically as part of the spacecraft. The Power and Propulsion Element (PPE) and the Habitation and Logistics Outpost (HALO) with the European System Providing Refueling, Infrastructure and Telecommunications (ESPRIT) HALO Lunar Communications System (HLCS) have begun manufacturing the long lead components and will be launched first as a Co-Manifested Vehicle (CMV). The International Habitat (I-Hab) and ESPRIT Refueling Module (ERM) are passing life cycle milestones and include capabilities key for human crewmembers, such as windows, private sleeping quarters, and galley functions. The Logistics Module (LM) may provide a variety of services to Gateway depending on each mission. Requirements for the airlock have been developed, including requests that it support the integrated spacecraft with functions like augmenting heat rejection capabilities, and interfaces with new spacesuits will soon be developed in more detail. As a critical element of the architecture for solar system exploration, Gateway implements key tenets and features of international interoperability standards necessary to operate with multiple visiting vehicles and lunar assets, especially avionics, communications, and docking. Specific choices such as software architecture and standards, power standards, and robotics standards make it possible to utilize heritage or proprietary technology, yet still operate as one spacecraft. Engineering teams are evaluating many possible future missions to be executed at or utilizing the Gateway. The system architecture protects for an evolvable, extensible, and flexible capability. Designing systems robust enough to serve as a cornerstone of exploration activities for decades while remaining adaptable is not without its challenges. The detailed integration activities have revealed challenges and the need to mature key technologies. Refueling is a key component of achieving long life for Gateway, with unique operations to plan, safety concerns to mitigate, and risk reduction activities to conduct to better understand the system. The constraints and impacts of the design of visiting vehicles is also an important concern, with orientation constraints, control of attitude and orbit of the Gateway with docked visiting vehicles. Tradeoffs between robust maintainable systems and lightweight, compact systems must be balanced. Opportunities still exist for adding additional advanced capabilities to increase and extend Gateway’s benefits, such as intravehicular robotics, autonomous Guidance Navigation and Control (GN&C), and augmented control propulsion, heat rejection, or other services.