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At least 1,225 records · Page 68

SU-F-BRD-01: A Logistic Regression Model to Predict Objective Function Weights in Prostate Cancer IMRT

Purpose: To develop a statistical model that predicts optimization objective function weights from patient geometry for intensity-modulation radiotherapy (IMRT) of prostate cancer. Methods: A previously developed inverse optimization method (IOM) is applied retrospectively to determine optimal weights for 51 treated patients. We use an overlap volume ratio (OVR) of bladder and rectum for different PTV expansions in order to quantify patient geometry in explanatory variables. Using the optimal weights as ground truth, we develop and train a logistic regression (LR) model to predict the rectum weight and thus the bladder weight. Post hoc, we fix the weights of the left femoral head, right femoral head, and an artificial structure that encourages conformity to the population average while normalizing the bladder and rectum weights accordingly. The population average of objective function weights is used for comparison. Results: The OVR at 0.7cm was found to be the most predictive of the rectum weights. The LR model performance is statistically significant when compared to the population average over a range of clinical metrics including bladder/rectum V53Gy, bladder/rectum V70Gy, and mean voxel dose to the bladder, rectum, CTV, and PTV. On average, the LR model predicted bladder and rectum weights that are both 63% closer to the optimal weights compared to the population average. The treatment plans resulting from the LR weights have, on average, a rectum V70Gy that is 35% closer to the clinical plan and a bladder V70Gy that is 43% closer. Similar results are seen for bladder V54Gy and rectum V54Gy. Conclusion: Statistical modelling from patient anatomy can be used to determine objective function weights in IMRT for prostate cancer. Our method allows the treatment planners to begin the personalization process from an informed starting point, which may lead to more consistent clinical plans and reduce overall planning time.

60 APPLIED LIFE SCIENCES↗

Aeroacoustic Characterization of Optimum Hovering Rotors using Artificial Neural Networks

This work illustrates the use of artificial neural network modeling in the aerodynamic and aeroacoustic characterization of optimum hovering rotors over a broad range of design and operating conditions. Design of Experiments was used to create input feature spaces over eight input factors: the number of rotor blades, rotor radius, rotor rotation rate, design thrust condition, collective pitch, airfoil camber, the location of maximum camber, and the airfoil thickness. A low-fidelity tool chain was then used at the discrete data points defined by the designed input feature spaces to analytically design optimum hovering rotors and simulate aerodynamic and aeroacoustic quantities. This allowed for the generation of data sets over which to train and test the artificial neural network prediction models. Prediction models were trained over the data sets for the actual thrust generated by the rotor, power loading, tonal thickness and loading noise at the fundamental blade passage frequency, and broadband self-noise at seventeen one-third octave bands between 1 kHz and 40 kHz. These prediction models were validated by testing over data previously unseen by the models to quantify their capability for generalization to new data within the design feature space. The models were then used to study the effect each input feature had on the aeroacoustics and aerodynamics of optimum hovering rotors and physical insights were concluded to further explain the effect of each input. This characterization study showed that tonal noise and power loading were most sensitive to the number of rotor blades and the rotor rotation rate and that broadband noise was most sensitive to collective pitch and the design thrust condition.

Christopher S Thurman↗

A Discrete-Time Average Model Based Predictive Control for Quasi-Z-Source Inverter

A discrete-time average model-based predictive control (DTA-MPC) is proposed for a quasi-Z-source inverter (qZSI). As a single-stage inverter topology, the qZSI regulates the dc-link voltage and the ac output voltage through the shoot-through (ST) duty cycle and the modulation index. Several feedback strategies have been dedicated to produce these two control variables, among which the most popular are the proportional–integral (PI)-based control and the conventional model-predictive control (MPC). However, in the former, there are tradeoffs between fast response and stability; the latter is robust, but at the cost of high calculation burden and variable switching frequency. Moreover, they require an elaborated design or fine tuning of controller parameters. The proposed DTA-MPC predicts future behaviors of the ST duty cycle and modulation signals, based on the established discrete-time average model of the quasi-Z-source (qZS) inductor current, the qZS capacitor voltage, and load currents. The prediction actions are applied to the qZSI modulator in the next sampling instant, without the need of other controller parameters’ design. A constant switching frequency and significantly reduced computations are achieved with high performance. Transient responses and steady-state accuracy of the qZSI system under the proposed DTA-MPC are investigated and compared with the PI-based control and the conventional MPC. Simulation and experimental results verify the effectiveness of the proposed approach for the qZSI.

42 ENGINEERING↗

Review and developments of dissemination models for airborne carbon fibers

Dissemination prediction models were reviewed to determine their applicability to a risk assessment for airborne carbon fibers. The review showed that the Gaussian prediction models using partial reflection at the ground agreed very closely with a more elaborate diffusion analysis developed for the study. For distances beyond 10,000 m the Gaussian models predicted a slower fall-off in exposure levels than the diffusion models. This resulting level of conservatism was preferred for the carbon fiber risk assessment. The results also showed that the perfect vertical-mixing models developed herein agreed very closely with the diffusion analysis for all except the most stable atmospheric conditions.

Elber, W.↗

Optimized Machine Learning Model for Predicting Groundwater Contamination

The use of physical models to predict groundwater contaminant movement remains technically challenging due to the complexity of the phenomena, the heterogeneity of key parameters in nature, and the presence of poorly defined interactive and feedback processes. New approaches to address these challenges are needed. In this study, we evaluate various Artificial Intelligence (AI)-based approaches to understand a hexavalent chromium (Cr(VI)) plumes located on the U.S. Department of Energy’s (DOE) Hanford Site in Richland, WA. The groundwater monitoring dataset used in this study included data from the 100 Area along the Columbia River and included data collected between 2010 to 2019. This study investigates the most prominent contaminant, Cr(VI), with the Extreme Gradient Boosting (XGBoost) machine learning model. The XGBoost models were compared with optimized versions using an Empirical Bayes Search Cross-Validation technique for better prediction. The optimized XGBoost model yielded an R^2 value of 0.99 on the training set and 0.85 on the testing set, whereas XGBoost without optimization yielded a value of 0.83 on the training set and 0.85 on the testing set. This paper provides an overview of a computational method for groundwater contamination modeling that shows promise for improving current remediation efforts.

Mazumdar, Hirak↗

Reusable Solid Rocket Motor Nozzle Joint-4 Thermal Analysis

This study provides for development and test verification of a thermal model used for prediction of joint heating environments, structural temperatures and seal erosions in the Space Shuttle Reusable Solid Rocket Motor (RSRM) Nozzle Joint-4. The heating environments are a result of rapid pressurization of the joint free volume assuming a leak path has occurred in the filler material used for assembly gap close out. Combustion gases flow along the leak path from nozzle environment to joint O-ring gland resulting in local heating to the metal housing and erosion of seal materials. Analysis of this condition was based on usage of the NASA Joint Pressurization Routine (JPR) for environment determination and the Systems Improved Numerical Differencing Analyzer (SINDA) for structural temperature prediction. Model generated temperatures, pressures and seal erosions are compared to hot fire test data for several different leak path situations. Investigated in the hot fire test program were nozzle joint-4 O-ring erosion sensitivities to leak path width in both open and confined joint geometries. Model predictions were in generally good agreement with the test data for the confined leak path cases. Worst case flight predictions are provided using the test-calibrated model. Analysis issues are discussed based on model calibration procedures.

Clayton, J. Louie↗

An Efficient Deterministic Approach to Model-based Prediction Uncertainty Estimation

Prognostics deals with the prediction of the end of life (EOL) of a system. EOL is a random variable, due to the presence of process noise and uncertainty in the future inputs to the system. Prognostics algorithm must account for this inherent uncertainty. In addition, these algorithms never know exactly the state of the system at the desired time of prediction, or the exact model describing the future evolution of the system, accumulating additional uncertainty into the predicted EOL. Prediction algorithms that do not account for these sources of uncertainty are misrepresenting the EOL and can lead to poor decisions based on their results. In this paper, we explore the impact of uncertainty in the prediction problem. We develop a general model-based prediction algorithm that incorporates these sources of uncertainty, and propose a novel approach to efficiently handle uncertainty in the future input trajectories of a system by using the unscented transformation. Using this approach, we are not only able to reduce the computational load but also estimate the bounds of uncertainty in a deterministic manner, which can be useful to consider during decision-making. Using a lithium-ion battery as a case study, we perform several simulation-based experiments to explore these issues, and validate the overall approach using experimental data from a battery testbed.

Daigle, Matthew J.↗

Combination of searches for heavy resonances decaying into bosonic and leptonic final states using 36 fb - 1 of proton-proton collision data at s = 13 TeV with the ATLAS detector

Searches for new heavy resonances decaying into different pairings of W, Z, or Higgs bosons, as well as directly into leptons, are presented using a data sample corresponding to 36.1 fb -1 of pp collisions at $ \sqrt{s}=13 $ TeV collected during 2015 and 2016 with the ATLAS detector at the CERN Large Hadron Collider. Analyses selecting bosonic decay modes in the qqqq, ννqq, ℓνqq, ℓℓqq, ℓνℓν, ℓℓνν, ℓνℓℓ, ℓℓℓℓ, qqbb, ννbb, ℓνbb, and ℓℓbb final states are combined, searching for a narrow-width resonance. Likewise, analyses selecting the leptonic ℓν and ℓℓ final states are also combined. These two sets of analyses are then further combined. No significant deviation from the Standard Model predictions is observed. Three benchmark models are tested: a model predicting the existence of a new heavy scalar singlet, a simplified model predicting a heavy vector-boson triplet, and a bulk Randall-Sundrum model with a heavy spin-2 Kaluza-Klein excitation of the graviton. Cross section limits are set at the 95% confidence level using an asymptotic approximation and are compared with predictions for the benchmark models. These limits are also expressed in terms of constraints on couplings of the heavy vector-boson triplet to quarks, leptons, and the Higgs boson. The data exclude a heavy vector-boson triplet with mass below 5.5 TeV in a weakly coupled scenario and 4.5 TeV in a strongly coupled scenario, as well as a Kaluza-Klein graviton with mass below 2.3 TeV.

72 PHYSICS OF ELEMENTARY PARTICLES AND FIELDS↗

Searches for heavy diboson resonances in pp collisions at $ \sqrt{s}=13 $ TeV with the ATLAS detector

Searches for new heavy resonances decaying to WW, WZ, and ZZ bosons are presented, using a data sample corresponding to 3.2 fb -1 of pp collisions at s=13 TeV colle cted with the ATLAS detector at the CERN Large Hadron Collider. Analyses selecting ννqq, ℓνqq, ℓℓqq and qqqq final states are combined, searching for an arrow-width resonance with mass between 500 and 3000 GeV. The discriminating variable is either an invariant mass or a transverse mass. No significant deviations from the Standard Model predictions are observed. Three benchmark models are tested: a model predicting the existence of a new heavy scalar singlet, a simplified model predicting a heavy vector-boson triplet, and a bulk Randall-Sundrum model with a heavy spin-2 graviton. Cross-section limits are set at the 95% confidence level and are compared to theoretical cross-section predictions for a variety of models. The data exclude a scalar singlet with mass below 2650 GeV, a heavy vector-boson triplet with mass below 2600 GeV, and a graviton with mass below 1100 GeV. These results significantly extend the previous limits set using pp collisions at √s=8 TeV.

72 PHYSICS OF ELEMENTARY PARTICLES AND FIELDS↗

Impact of Land Model Calibration on Coupled Land-Atmosphere Prediction

Land-atmosphere (L-A) interactions play a critical role in determining the diurnal evolution of both planetary boundary layer (PBL) and land surface heat and moisture budgets, as well as controlling feedbacks with clouds and precipitation that lead to the persistence of dry and wet regimes. Recent efforts to quantify the strength of L-A coupling in prediction models have produced diagnostics that integrate across both the land and PBL components of the system. In this study, we examine the impact of improved specification of land surface states, anomalies, and fluxes on coupled WRF forecasts during the summers of extreme dry and wet land surface conditions in the U.S. Southern Great Plains. The improved land initialization and surface flux parameterizations are obtained through calibration of the Noah land surface model using the new optimization and uncertainty estimation subsystem in NASA's Land Information System (LIS-OPT/UE). The impact of the calibration on the a) spinup of the land surface used as initial conditions, and b) the simulated heat and moisture states and fluxes of the coupled WRF simulations is then assessed. Changes in ambient weather and land-atmosphere coupling are evaluated along with measures of uncertainty propagation into the forecasts. In addition, the sensitivity of this approach to the period of calibration (dry, wet, average) is investigated. Results indicate that the offline calibration leads to systematic improvements in land-PBL fluxes and near-surface temperature and humidity, and in the process provide guidance on the questions of what, how, and when to calibrate land surface models for coupled model prediction.

Santanello, Joseph A., Jr.↗

Aluminum cladding oxide growth prediction for high flux research reactors

Aluminum cladding oxidation of research-reactor fuel elements at high power conditions has a disadvantageous effect on fuel performance due to the lower thermal conductivity of the oxide. The oxide growth prediction models available in the literature were mostly developed for low power conditions. To examine the applicability of the models to high power and high temperature test conditions, the models were studied by coupling with the most frequently employed heat transfer coefficient (HTC) correlations including the Dittus-Boelter correlation, the Colburn correlation, the Sieder-Tate correlation, and KAERI-developed correlation. The Griess model over-predicted the oxide growth while the KAERI-Griess model under-predicted the oxide growth for high power tests. The Kim model, coupled with the Colburn correlation, gave most consistent results with the measured data from two BR2 experiments. However, the Kim model was found to be inapplicable to the EUHFRR conditions at the peak power locations if it was coupled with the Dittus-Boelter correlation. A revision of the prediction models to more closely agree with the measured data was recommended. Furthermore, AG3NE and AlFeNi cladding types were tested in the E-FUTURE experiment, and a noticeable (although small) reduction in oxide thickness on the AlFeNi cladding was observed. However, this difference was believed to be only a secondary effect considering other uncertainties in model predictions, so no attempt was made to model the alloying effect.

21 SPECIFIC NUCLEAR REACTORS AND ASSOCIATED PLANTS↗

Development and Evaluation of Occupancy-Aware HVAC Control for Residential Building Energy Efficiency and Occupant Comfort

Occupancy-aware heating, ventilation, and air conditioning (HVAC) control offers the opportunity to reduce energy use without sacrificing thermal comfort. Residential HVAC systems often use manually-adjusted or constant setpoint temperatures, which heat and cool the house regardless of whether it is needed. By incorporating occupancy-awareness into HVAC control, heating and cooling can be used for only those time periods it is needed. Yet, bringing this technology to fruition is dependent on accurately predicting occupancy. Non-probabilistic prediction models offer an opportunity to use collected occupancy data to predict future occupancy profiles. Smart devices, such as a connected thermostat, which already include occupancy sensors, can be used to provide a continually growing collection of data that can then be harnessed for short-term occupancy prediction by compiling and creating a binary occupancy prediction. Real occupancy data from six homes located in Colorado is analyzed and investigated using this occupancy prediction model. Results show that non-probabilistic occupancy models in combination with occupancy sensors can be combined to provide a hybrid HVAC control with savings on average of 5.0% and without degradation of thermal comfort. Model predictive control provides further opportunities, with the ability to adjust the relative importance between thermal comfort and energy savings to achieve savings between 1% and 13.3% depending on the relative weighting between thermal comfort and energy savings. In all cases, occupancy prediction allows the opportunity for a more intelligent and optimized strategy to residential HVAC control.

32 ENERGY CONSERVATION, CONSUMPTION, AND UTILIZATI↗

Mathematical model for predicting human vertebral fracture

Mathematical model has been constructed to predict dynamic response of tapered, curved beam columns in as much as human spine closely resembles this form. Model takes into consideration effects of impact force, mass distribution, and material properties. Solutions were verified by dynamic tests on curved, tapered, elastic polyethylene beam.

Benedict, J. V.↗

Liquid Core Detection and Strand Condition Monitoring in a Continuous Caster Using Optical Fiber

Real-time monitoring of the liquid core position during the continuous casting of steel has been demonstrated using low-cost distributed optical-fiber-based strain sensors. These sensors were installed on the containment roll support structures in the segments of a production continuous caster to detect the position of the solid–liquid interface and monitor the strand condition during the continuous casting. Distributed Fiber Bragg Grating sensors (FBGs) were used in this work to monitor strain at six roll positions in the caster. The sensor performance was first validated by comparing optical strain measurements with conventional strain gauge measurements in the lab. Next, optical strain measurements were performed on an isolated caster segment in a segment maintenance facility using hydraulic jacks to simulate the presence of a liquid core under the roll. Finally, the sensors were evaluated during caster operation. The sensors successfully detected the load increase associated with the presence of a liquid core under each instrumented roll location. Incidents of bulging and roll eccentricity were also detected using frequency analysis of the optical strain signal. The liquid core position measurements were compared using predictions from computer models (digital twins) in use at the production site. The measurements were in good agreement with the model predictions, with a few exceptions. Under certain transient caster operating conditions, such as spraying practice changes and SEN exchanges, the model predictions deviated slightly from the liquid core position determined from strain measurements.

47 OTHER INSTRUMENTATION↗

Mean Climate and Tropical Rainfall Variability in Aquaplanet Simulations Using the Model for Prediction Across Scales‐Atmosphere

Abstract Aquaplanet experiments are important tools for understanding and improving physical processes simulated by global models; yet, previous aquaplanet experiments largely differ in their representation of subseasonal tropical rainfall variability. This study presents results from aquaplanet experiments produced with the Model for Prediction Across Scales‐Atmosphere (MPAS‐A)—a community model specifically designed to study weather and climate in a common framework. The mean climate and tropical rainfall variability simulated by MPAS‐A with varying horizontal resolution were compared against results from a recent suite of aquaplanet experiments. This comparison shows that, regardless of horizontal resolution, MPAS‐A produces the expected mean climate of an aquaplanet framework with zonally symmetric but meridionally varying sea‐surface temperature. MPAS‐A, however, has a stronger signal of tropical rainfall variability driven by convectively coupled equatorial waves. Sensitivity experiments with different cumulus parameterizations, physics packages, and vertical grids consistently show the presence of those waves, especially equatorial Kelvin waves, in phase with lower‐tropospheric convergence. Other models do not capture such rainfall‐kinematics phasing. These results suggest that simulated tropical rainfall variability depends not only on the cumulus parameterization (as suggested by previous studies) but also on the coupling between physics and dynamics of climate and weather prediction models.

Rios‐Berrios, R.↗

Modeling the effectiveness of remediation efforts in contaminated urban areas: An EMRAS II Urban Areas Working Group exercise - 15631

The Urban Areas Working Group was part of the IAEA's EMRAS II (Environmental Modelling for Radiation Safety) Programme during 2009-2011. The Working Group's goal was to test and improve the capabilities of models used in assessment of radioactive contamination in urban settings. The 'contaminant transport and countermeasures' exercise was focused on modeling the effectiveness of potential countermeasures or remediation efforts with respect to reduction of human exposures and doses. The exercise was based on a hypothetical situation involving an initial concentration of Co-60 or Pu-239 in air in a specified urban area. Participants were given detailed input information, including descriptions of test locations in two types of urban areas, (1) a business area with buildings and asphalt, and (2) a park area near an apartment town. Several kinds of initial weather conditions (dry, light rain, and heavy rain) were explored. Modeling endpoints included contamination densities, dose rates (from each contributing surface and total), annual and cumulative doses (internal and external) for specified reference individuals, and effectiveness of countermeasures and remediation efforts in terms of dose rate reduction and dose reduction. External doses were emphasized for Co-60 and internal doses for Pu-239. Approaches and model predictions from five models are compared, and explanations for similarities and differences among model predictions are offered. Understanding the effects of different approaches, assumptions, and parameter values is essential to a comparison of results from different models and to understanding both the usefulness and the limitations of any given model. (authors)

54 ENVIRONMENTAL SCIENCES↗

Collaborative Research: Separating Forced and Unforced Decadal Predictability in Models and Observations

This report is a progress report of the accomplishments of the research grant “Collaborative Research: Separating Forced and Unforced Decadal Predictability in Models and Observations” during the period 1 May 2011- 31 August 2013. This project is a collaborative one between Columbia University and George Mason University. George Mason University will submit a final technical report at the conclusion of their no-cost extension. The purpose of the proposed research is to identify unforced predictable components on decadal time scales, distinguish these components from forced predictable components, and to assess the reliability of model predictions of these components. Components of unforced decadal predictability will be isolated by maximizing the Average Predictability Time (APT) in long, multimodel control runs from state-of-the-art climate models. Components with decadal predictability have large APT, so maximizing APT ensures that components with decadal predictability will be detected. Optimal fingerprinting techniques, as used in detection and attribution analysis, will be used to separate variations due to natural and anthropogenic forcing from those due to unforced decadal predictability. This methodology will be applied to the decadal hindcasts generated by the CMIP5 project to assess the reliability of model projections. The question of whether anthropogenic forcing changes decadal predictability, or gives rise to new forms of decadal predictability, also will be investigated.

54 ENVIRONMENTAL SCIENCES↗

On Convergence of Development Costs and Cost Models for Complex Spaceflight Instrument Electronics

Development costs of a few recent spaceflight instrument electrical and electronics subsystems have diverged from respective heritage cost model predictions. The cost models used are Grass Roots, Price-H and Parametric Model. These cost models originated in the military and industry around 1970 and were successfully adopted and patched by NASA on a mission-by-mission basis for years. However, the complexity of new instruments recently changed rapidly by orders of magnitude. This is most obvious in the complexity of representative spaceflight instrument electronics' data system. It is now required to perform intermediate processing of digitized data apart from conventional processing of science phenomenon signals from multiple detectors. This involves on-board instrument formatting of computational operands from row data for example, images), multi-million operations per second on large volumes of data in reconfigurable hardware (in addition to processing on a general purpose imbedded or standalone instrument flight computer), as well as making decisions for on-board system adaptation and resource reconfiguration. The instrument data system is now tasked to perform more functions, such as forming packets and instrument-level data compression of more than one data stream, which are traditionally performed by the spacecraft command and data handling system. It is furthermore required that the electronics box for new complex instruments is developed for one-digit watt power consumption, small size and that it is light-weight, and delivers super-computing capabilities. The conflict between the actual development cost of newer complex instruments and its electronics components' heritage cost model predictions seems to be irreconcilable. This conflict and an approach to its resolution are addressed in this paper by determining the complexity parameters, complexity index, and their use in enhanced cost model.

Kizhner, Semion↗