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At least 1,225 records · Page 68

Magnetic Resonance Imaging–Guided versus Surrogate-Based Motion Tracking in Liver Radiation Therapy: A Prospective Comparative Study

Purpose: This study applied automatic feature detection on cine–magnetic resonance imaging (MRI) liver images in order to provide a prospective comparison between MRI-guided and surrogate-based tracking methods for motion-compensated liver radiation therapy. Methods and Materials: In a population of 30 subjects (5 volunteers plus 25 patients), 2 oblique sagittal slices were acquired across the liver at high temporal resolution. An algorithm based on scale invariant feature transform (SIFT) was used to extract and track multiple features throughout the image sequence. The position of abdominal markers was also measured directly from the image series, and the internal motion of each feature was quantified through multiparametric analysis. Surrogate-based tumor tracking with a state-of-the-art external/internal correlation model was simulated. The geometrical tracking error was measured, and its correlation with external motion parameters was also investigated. Finally, the potential gain in tracking accuracy relying on MRI guidance was quantified as a function of the maximum allowed tracking error. Results: An average of 45 features was extracted for each subject across the whole liver. The multi-parametric motion analysis reported relevant inter- and intrasubject variability, highlighting the value of patient-specific and spatially-distributed measurements. Surrogate-based tracking errors (relative to the motion amplitude) were were in the range 7% to 23% (1.02-3.57mm) and were significantly influenced by external motion parameters. The gain of MRI guidance compared to surrogate-based motion tracking was larger than 30% in 50% of the subjects when considering a 1.5-mm tracking error tolerance. Conclusions: Automatic feature detection applied to cine-MRI allows detailed liver motion description to be obtained. Such information was used to quantify the performance of surrogate-based tracking methods and to provide a prospective comparison with respect to MRI-guided radiation therapy, which could support the definition of patient-specific optimal treatment strategies.

62 RADIOLOGY AND NUCLEAR MEDICINE↗

Experimental Simulations of Field-Induced Mechanical Abuse Conditions

Mechanical failure of cell components is an important component to understanding safety outcomes for batteries subjected to external loading. Several key parameters governing the mechanical response at the component to the module level are discussed in this chapter. Specifically, nuances associated with experimental measurements of these properties – including development of test methods, fixturing the test articles, ways to minimize errors in measurements, and improving the repeatability of some of these experiments – are examined closely.

Torres-castro, Loraine↗

Eddy current flow meter model validation with a moving solid rod*

We report that the eddy current flow meter (ECFM) has been used to measure velocities and temperatures of conductive flows, such as liquid metal flows in a nuclear fission reactor. The goal of this paper is to develop a finite element electromagnetic model that can characterize the ECFM sensor performance and validate this finite element model with detailed velocity measurements of a controlled, well-characterized moving conductive solid rod. Both measurements and modeling were performed for various parameters that are important for ECFM performance such as rod velocity, rod material, ECFM sensor coil length, number of sensor coils, applied alternating current (AC) current amplitude, and applied ECFM AC frequency. For all parametric scans, the measurement and modeling agree well in both magnitude and trend. The normalized root-mean-square error between measurement and modeling is less than 10% for all cases. These results suggest that electromagnetic modeling could eventually be used to cost-effectively design future ECFM sensors in arbitrary geometry for more challenging applications such as liquid metal nuclear fission reactors.

47 OTHER INSTRUMENTATION↗

SU-E-J-145: Geometric Uncertainty in CBCT Extrapolation for Head and Neck Adaptive Radiotherapy

Purpose: One primary limitation of using CBCT images for H'N adaptive radiotherapy (ART) is the limited field of view (FOV) range. We propose a method to extrapolate the CBCT by using a deformed planning CT for the dose of the day calculations. The aim was to estimate the geometric uncertainty of our extrapolation method. Methods: Ten H'N patients, each with a planning CT (CT1) and a subsequent CT (CT2) taken, were selected. Furthermore, a small FOV CBCT (CT2short) was synthetically created by cropping CT2 to the size of a CBCT image. Then, an extrapolated CBCT (CBCTextrp) was generated by deformably registering CT1 to CT2short and resampling with a wider FOV (42mm more from the CT2short borders), where CT1 is deformed through translation, rigid, affine, and b-spline transformations in order. The geometric error is measured as the distance map ||DVF|| produced by a deformable registration between CBCTextrp and CT2. Mean errors were calculated as a function of the distance away from the CBCT borders. The quality of all the registrations was visually verified. Results: Results were collected based on the average numbers from 10 patients. The extrapolation error increased linearly as a function of the distance (at a rate of 0.7mm per 1 cm) away from the CBCT borders in the S/I direction. The errors (μ±σ) at the superior and inferior boarders were 0.8 ± 0.5mm and 3.0 ± 1.5mm respectively, and increased to 2.7 ± 2.2mm and 5.9 ± 1.9mm at 4.2cm away. The mean error within CBCT borders was 1.16 ± 0.54mm . The overall errors within 4.2cm error expansion were 2.0 ± 1.2mm (sup) and 4.5 ± 1.6mm (inf). Conclusion: The overall error in inf direction is larger due to more large unpredictable deformations in the chest. The error introduced by extrapolation is plan dependent. The mean error in the expanded region can be large, and must be considered during implementation. This work is supported in part by Varian Medical Systems, Palo Alto, CA.

60 APPLIED LIFE SCIENCES↗

Development of a transfer function method for dynamic stability measurement

Flutter testing method based on transfer function measurements is developed. The error statistics of several dynamic stability measurement methods are reviewed. It is shown that the transfer function measurement controls the error level by averaging the data and correlating the input and output. The method also gives a direct estimate of the error in the response measurement. An algorithm is developed for obtaining the natural frequency and damping ratio of low damped modes of the system, using integrals of the transfer function in the vicinity of a resonant peak. Guidelines are given for selecting the parameters in the transfer function measurement. Finally, the dynamic stability measurement technique is applied to data from a wind tunnel test of a proprotor and wing model.

Johnson, W.↗

Digital high density (80 Mb/s) tape

Work with a state-of-the-art high density PCM tape recorder reproducer system is described. The tape recorder is designed for 80 Mb/s operation at an overall bit error rate of .00001and for 40 Mb/s operation at .000001. The article describes the process of measuring the error rate. Also detailed is a data rate buffer designed for use in recent radar experiments and generalizable to most potential uses of the recorder system.

Donner, M. D.↗

A numerical algorithm to propagate navigation error covariance matrices associated with generalized strapdown inertial measurement units

The design and operation of a Strapdown Navigation Analysis Program (SNAP) developed to perform covariance analysis on spacecraft inertial-measurement-unit (IMU) navigation errors are described and demonstrated. Consideration is given to the IMU modeling subroutine (with user-specified sensor characteristics), the data input procedures, state updates and the simulation of instrument failures, the determination of the nominal trajectory, the mapping-matrix and Monte Carlo covariance-matrix propagation methods, and aided-navigation simulation. Numerical results are presented in tables for sample applications involving (1) the Galileo/IUS spacecraft from its deployment from the Space Shuttle to a point 10 to the 8th ft from the center of the earth and (2) the TDRS-C/IUS spacecraft from Space Shuttle liftoff to a point about 2 h before IUS deployment. SNAP is shown to give reliable results for both cases, with good general agreement between the mapping-matrix and Monte Carlo predictions.

Weir, Kent A.↗

Two-Season Atacama Cosmology Telescope Polarimeter Lensing Power Spectrum

We report a measurement of the power spectrum of cosmic microwave background (CMB) lensing from two seasons of Atacama Cosmology Telescope polarimeter (ACTPol) CMB data. The CMB lensing power spectrum is extracted from both temperature and polarization data using quadratic estimators. We obtain results that are consistent with the expectation from the best-fit Planck CDM model over a range of multipoles L 80-2100, with an amplitude of lensing A(sub lens) = 1.06 +/- 0.15 stat +/- 0.06 sys relative to Planck. Our measurement of the CMB lensing power spectrum gives sigma 8 omega m(sup 0.25) = 0.643 +/- 0.054; including baryon acoustic oscillation scale data, we constrain the amplitude of density fluctuations to be sigma 8 = 0.831 +/- 0.053. We also update constraints on the neutrino mass sum. We verify our lensing measurement with a number of null tests and systematic checks, finding no evidence of significant systematic errors. This measurement relies on a small fraction of the ACTPol data already taken; more precise lensing results can therefore be expected from the full ACTPol data set.

Shewin, Blake D.↗

Ultra Low Level Environmental Neutron Measurements Using Superheated Droplet Detectors

Through the application of superheated droplet detectors (SDDs), the SIMPLE project for the direct search for dark matter (DM) reached the most restrictive limits on the spin-dependent sector to date. The experiment is based on the detection of recoils following WIMP-nuclei interaction, mimicking those from neutron scattering. The thermodynamic operation conditions yield the SDDs intrinsically insensitive to radiations with linear energy transfer below ∼150 keVμm{sup -1} such as photons, electrons, muons and neutrons with energies below ∼40 keV. Underground facilities are increasingly employed for measurements in a low-level radiation background (DM search, gamma-spectroscopy, intrinsic soft-error rate measurements, etc.), where the rock overburden shields against cosmic radiation. In this environment the SDDs are sensitive only to α-particles and neutrons naturally emitted from the surrounding materials. Recently developed signal analysis techniques allow discrimination between neutron and α-induced signals. SDDs are therefore a promising instrument for low-level neutron and α measurements, namely environmental neutron measurements and α-contamination assays. In this work neutron measurements performed in the challenging conditions of the latest SIMPLE experiment (1500 mwe depth with 50-75 cm water shield) are reported. The results are compared with those obtained by detailed Monte Carlo simulations of the neutron background induced by {sup 238}U and {sup 232}Th traces in the facility, shielding and detector materials. Calculations of the neutron energy distribution yield the following neutron fluence rates (in 10{sup -8} cm{sup -2}s{sup -1}): thermal (<0.5 eV): 2.5; epithermal (0.5 eV-100 keV): 2.2; fast (>1 MeV): 3.9. Signal rates were derived using standard cross sections and codes routinely employed in reactor dosimetry. The measured and calculated neutron count rates per unit of active mass were 0.15 ct/kgd and 0.33 ct/kg-d respectively. As the major signal contribution (98%) originates from radio-impurities in the detector container, alternative materials will be employed in future devices. Latest results regarding the improvement of the detector characterization accuracy towards its application in environmental neutron detection are in progress and will be described. (authors)

46 INSTRUMENTATION RELATED TO NUCLEAR SCIENCE AND ↗

Application of Statistical Filter Theory to the Optimal Estimation of Position and Velocity on Board a Circumlunar Vehicle

Concepts from statistical filter theory are applied to the problem of in-flight determination of the position and velocity of a space vehicle for the purposes of midcourse guidance. The source of information is assumed to be an arbitrary sequence of measurements of any desired set of "observables" (e.g., space angles), the measurements being corrupted by additive errors so that the position and velocity are never known perfectly. A state transition approach is employed which leads naturally to a computational scheme that is readily implemented by a digital computer. The scheme can be regarded as a dynamical time-varying filter which weights the incoming observations in an optimal sense for use in producing an up-to-date optimal estimate of position and velocity. The advantages of the scheme are (1) it provides the best possible estimate (minimum error) based upon ensemble statistics of injection conditions and measurement errors; (2) it is extremely versatile, not requiring adherence to a predetermined observation schedule or reference trajectory; and (3) the computations are sufficiently simple to be practical in an on-board computer. A digital computer simulation of the proposed system is employed to demonstrate the feasibility of an all on-board system and to illustrate the performance attainable in a hypothetical physical situation.

SPACE VEHICLE↗

Technique for Radiometer and Antenna Array Calibration - TRAAC

Highly sensitive receivers are used to detect minute amounts of emitted electromagnetic energy. Calibration of these receivers is vital to the accuracy of the measurements. Traditional calibration techniques depend on calibration reference internal to the receivers as reference for the calibration of the observed electromagnetic energy. Such methods can only calibrate errors in measurement introduced by the receiver only. The disadvantage of these existing methods is that they cannot account for errors introduced by devices, such as antennas, used for capturing electromagnetic radiation. This severely limits the types of antennas that can be used to make measurements with a high degree of accuracy. Complex antenna systems, such as electronically steerable antennas (also known as phased arrays), while offering potentially significant advantages, suffer from a lack of a reliable and accurate calibration technique. The proximity of antenna elements in an array results in interaction between the electromagnetic fields radiated (or received) by the individual elements. This phenomenon is called mutual coupling. The new calibration method uses a known noise source as a calibration load to determine the instantaneous characteristics of the antenna. The noise source is emitted from one element of the antenna array and received by all the other elements due to mutual coupling. This received noise is used as a calibration standard to monitor the stability of the antenna electronics.

Meyer, Paul↗

Variation in surface properties as error sources in dynamic temperature measurements

Most temperature measurement methods rely upon the assumption of a single uniform source as part of the analysis in inferring an observed temperature T from the surface of a material. This is true for the radiometric and spectroscopic methods we rely upon in shock physics. However, there are obvious cases where this is a poor assumption that can cause large errors in analysis, such as the measurement of emission from a surface composed of more than one material, such as a rusted surface of Fe and Fe 2 O 3 , or a multi-material surface that could be produced through alloying methods (e.g., mokume gane) or 3D printing. Here we perform an initial examination of the effects of varied surface properties upon the analysis using idealized test data to constrain when we may have better confidence in the resulting calculations. We also examine the structures of the fits to test whether, in principle, comparing the fit with ideal gray bodies would reveal such a structure and enable the researcher to identify when a two-temperature fitting model should be used instead of a single- T model or a wavelength-dependent emissivity model.

36 MATERIALS SCIENCE↗

Formal Verification of Safety Buffers for Sate-Based Conflict Detection and Resolution

The information provided by global positioning systems is never totally exact, and there are always errors when measuring position and velocity of moving objects such as aircraft. This paper studies the effects of these errors in the actual separation of aircraft in the context of state-based conflict detection and resolution. Assuming that the state information is uncertain but that bounds on the errors are known, this paper provides an analytical definition of a safety buffer and sufficient conditions under which this buffer guarantees that actual conflicts are detected and solved. The results are presented as theorems, which were formally proven using a mechanical theorem prover.

Herencia-Zapana, Heber↗

An Introduction to Global Navigation Satellite Systems

Products that rely on Global Navigation Satellite Systems (GNSS) have become an essential part of daily life for millions of people around the world. In addition to enabling navigation, these constellations of satellites and the signals they transmit provide a global, precise timing source, used in everything from electrical power grid phasing to synchronization of financial networks. This tutorial introduces the concept of radio navigation, describes the features of GNSS signals that make navigation possible, and explains how these signals are processed by GNSS receivers. The resulting measurements and error sources, such as atmospheric effects and multipath, are discussed. Then methods are presented for combining these measurements into a position, velocity, and time estimate. The tutorial concludes with a brief status report on the GNSS constellations, space applications and recent flight experiences, and active areas of research.

Ashman, Ben↗

Binary classification with noisy quantum circuits and noisy quantum data

We study the effects of single-qubit noises in the quantum circuit and the corruption in the quantum training data to the performance of binary classification problem. We find that under the presence of errors, the measurement at a qubit is affected only by the noise in the corresponding qubit, and that the errors on other qubits do not affect this outcome. Furthermore, for the task where we fit a binary classifier using a quantum training data, we show that the noise in the data can work as a regularizer, implying that we can benefit from the noise in certain cases. We support our findings with simulations.

Lee, Yonghoon↗

Two-Photon Laser-Induced Fluorescence O and N Atoms for the Study of Heterogeneous Catalysis in a Diffusion Reactor

Advanced laser-based diagnostics have been developed to examine catalytic effects and atom/surface interactions on thermal protection materials. This study establishes the feasibility of using laser-induced fluorescence for detection of O and N atom loss in a diffusion tube to measure surface catalytic activity. The experimental apparatus is versatile in that it allows fluorescence detection to be used for measuring species selective recombination coefficients as well as diffusion tube and microwave discharge diagnostics. Many of the potential sources of error in measuring atom recombination coefficients by this method have been identified and taken into account. These include scattered light, detector saturation, sample surface cleanliness, reactor design, gas pressure and composition, and selectivity of the laser probe. Recombination coefficients and their associated errors are reported for N and O atoms on a quartz surface at room temperature.

Pallix, Joan B.↗

An Internal Digital Image Correlation Technique for High-Strain Rate Dynamic Experiments

Full-field, quantitative visualization techniques, such as digital image correlation (DIC), have unlocked vast opportunities for experimental mechanics. However, DIC has traditionally been a surface measurement technique, and has not been extended to perform measurements on the interior of specimens for dynamic, full-scale laboratory experiments. This limitation restricts the scope of physics which can be investigated through DIC measurements, especially in the context of heterogeneous materials. The focus of this study is to develop a method for performing internal DIC measurements in dynamic experiments. The aim is to demonstrate its feasibility and accuracy across a range of stresses (up to 650 MPa), strain rates (10 3 - 10 6 s -1 ), and high-strain rate loading conditions (e.g., ramped and shock wave loading). Internal DIC is developed based on the concept of applying a speckle pattern at an inner-plane of a transparent specimen. The high-speed imaging configuration is coupled to the traditional dynamic experimental setups, and is focused on the internal speckle pattern. During the experiment, while the sample deforms dynamically, in-plane, two-dimensional deformations are measured via correlation of the internal speckle pattern. In this study, the viability and accuracy of the internal DIC technique is demonstrated for split-Hopkinson (Kolsky) pressure bar (SHPB) and plate impact experiments. The internal DIC experimental technique is successfully demonstrated in both the SHPB and plate impact experiments. In the SHPB setting, the accuracy of the technique is excellent throughout the deformation regime, with measurement noise of approximately 0.2% strain. In the case of plate impact experiments, the technique performs well, with error and measurement noise of 1% strain. The internal DIC technique has been developed and demonstrated to work well for full-scale dynamic high-strain rate and shock laboratory experiments, and the accuracy is quantified. Here, the technique can aid in investigating the physics and mechanics of the dynamic behavior of materials, including local deformation fields around dynamically loaded material heterogeneities.

36 MATERIALS SCIENCE↗