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At least 1,207 records · Page 67
All sourcesNASA NTRSDOE OSTI
NASA NTRS1999

Noninvasive assessment of left atrial maximum dP/dt by a combination of transmitral and pulmonary venous flow

OBJECTIVES: The study assessed whether hemodynamic parameters of left atrial (LA) systolic function could be estimated noninvasively using Doppler echocardiography. BACKGROUND: Left atrial systolic function is an important aspect of cardiac function. Doppler echocardiography can measure changes in LA volume, but has not been shown to relate to hemodynamic parameters such as the maximal value of the first derivative of the pressure (LA dP/dt(max)). METHODS: Eighteen patients in sinus rhythm were studied immediately before and after open heart surgery using simultaneous LA pressure measurements and intraoperative transesophageal echocardiography. Left atrial pressure was measured with a micromanometer catheter, and LA dP/dt(max) during atrial contraction was obtained. Transmitral and pulmonary venous flow were recorded by pulsed Doppler echocardiography. Peak velocity, and mean acceleration and deceleration, and the time-velocity integral of each flow during atrial contraction was measured. The initial eight patients served as the study group to derive a multilinear regression equation to estimate LA dP/dt(max) from Doppler parameters, and the latter 10 patients served as the test group to validate the equation. A previously validated numeric model was used to confirm these results. RESULTS: In the study group, LA dP/dt(max) showed a linear relation with LA pressure before atrial contraction (r = 0.80, p < 0.005), confirming the presence of the Frank-Starling mechanism in the LA. Among transmitral flow parameters, mean acceleration showed the strongest correlation with LA dP/dt(max) (r = 0.78, p < 0.001). Among pulmonary venous flow parameters, no single parameter was sufficient to estimate LA dP/dt(max) with an r2 > 0.30. By stepwise and multiple linear regression analysis, LA dP/dt(max) was best described as follows: LA dP/dt(max) = 0.1 M-AC +/- 1.8 P-V - 4.1; r = 0.88, p < 0.0001, where M-AC is the mean acceleration of transmitral flow and P-V is the peak velocity of pulmonary venous flow during atrial contraction. This equation was tested in the latter 10 patients of the test group. Predicted and measured LA dP/dt(max) correlated well (r = 0.90, p < 0.0001). Numerical simulation verified that this relationship held across a wide range of atrial elastance, ventricular relaxation and systolic function, with LA dP/dt(max) predicted by the above equation with r = 0.94. CONCLUSIONS: A combination of transmitral and pulmonary venous flow parameters can provide a hemodynamic assessment of LA systolic function.

NASA Discipline Cardiopulmonary↗
NASA NTRS2005

A Study in HRT Resolution: Seeking Maximum Sensitivity Among Variations in Sensing Element Material

The EXACT (Experiments Along Coexistence near Tricriticality) project endeavors to perform the most rigorous test to date of Renormalization Group theory. In most cases, the theory gives only approximate solutions, but it offers exact predictions in the case of the He-3-He-4 tricritical point. Currently, the project is focused on maximizing the performance of the low-temperature system's HRT (high resolution thermometer) near the tricritical point. The HRT uses a PdMn sensing element, the qualities of which change based on its Mn concentration and whether or not it is annealed. All sensing element combinations will be catalogued, and through the data, the optimum configuration will be reported.

Morales, Jeremy M.↗
NASA NTRS2006

Debris Flux Comparisons From The Goldstone Radar, Haystack Radar, and Hax Radar Prior, During, and After the Last Solar Maximum

The continual monitoring of low Earth orbit (LEO) debris environment using highly sensitive radars is essential for an accurate characterization of these dynamic populations. Debris populations are continually evolving since there are new debris sources, previously unrecognized debris sources, and debris loss mechanisms that are dependent on the dynamic space environment. Such radar data are used to supplement, update, and validate existing orbital debris models. NASA has been utilizing radar observations of the debris environment for over a decade from three complementary radars: the NASA JPL Goldstone radar, the MIT Lincoln Laboratory (MIT/LL) Long Range Imaging Radar (known as the Haystack radar), and the MIT/LL Haystack Auxiliary radar (HAX). All of these systems are highly sensitive radars that operate in a fixed staring mode to statistically sample orbital debris in the LEO environment. Each of these radars is ideally suited to measure debris within a specific size region. The Goldstone radar generally observes objects with sizes from 2 mm to 1 cm. The Haystack radar generally measures from 5 mm to several meters. The HAX radar generally measures from 2 cm to several meters. These overlapping size regions allow a continuous measurement of cumulative debris flux versus diameter from 2 mm to several meters for a given altitude window. This is demonstrated for all three radars by comparing the debris flux versus diameter over 200 km altitude windows for 3 nonconsecutive years from 1998 through 2003. These years correspond to periods before, during, and after the peak of the last solar cycle. Comparing the year to year flux from Haystack for each of these altitude regions indicate statistically significant changes in subsets of the debris populations. Potential causes of these changes are discussed. These analysis results include error bars that represent statistical sampling errors, and are detailed in this paper.

Stokely, C. L.↗
NASA NTRS1998

The Causes of Geomagnetic Storms During Solar Maximum

One of the oldest mysteries in geomagnetism is the linkage between solar and geomagnetic activity. The 11-year cycles of both the numbers of sunspots and Earth geomagnetic storms were first noted by Sabine (1852).

mass ejections plasma link↗
NASA NTRS2004

Maximum likelihood decoding analysis of Accumulate-Repeat-Accumulate Codes

Repeat-Accumulate (RA) codes are the simplest turbo-like codes that achieve good performance. However, they cannot compete with Turbo codes or low-density parity check codes (LDPC) as far as performance is concerned. The Accumulate Repeat Accumulate (ARA) codes, as a subclass of LDPC codes, are obtained by adding a pre-coder in front of RA codes with puncturing where an accumulator is chosen as a precoder. These codes not only are very simple, but also achieve excellent performance with iterative decoding. In this paper, the performance of these codes with (ML) decoding are analyzed and compared to random codes by very tight bounds. The weight distribution of some simple ARA codes is obtained, and through existing tightest bounds we have shown the ML SNR threshold of ARA codes approaches very closely to the performance of random codes. We have shown that the use of precoder improves the SNR threshold but interleaving gain remains unchanged with respect to RA code with puncturing.

low density parity codes (LDPC)↗
NASA NTRS2009

Open-Loop Pitch Table Optimization for the Maximum Dynamic Pressure Orion Abort Flight Test

NASA has scheduled the retirement of the space shuttle orbiter fleet at the end of 2010. The Constellation program was created to develop the next generation of human spaceflight vehicles and launch vehicles, known as Orion and Ares respectively. The Orion vehicle is a return to the capsule configuration that was used in the Mercury, Gemini, and Apollo programs. This configuration allows for the inclusion of an abort system that safely removes the capsule from the booster in the event of a failure on launch. The Flight Test Office at NASA's Dryden Flight Research Center has been tasked with the flight testing of the abort system to ensure proper functionality and safety. The abort system will be tested in various scenarios to approximate the conditions encountered during an actual Orion launch. Every abort will have a closed-loop controller with an open-loop backup that will direct the vehicle during the abort. In order to provide the best fit for the desired total angle of attack profile with the open-loop pitch table, the table is tuned using simulated abort trajectories. A pitch table optimization program was created to tune the trajectories in an automated fashion. The program development was divided into three phases. Phase 1 used only the simulated nominal run to tune the open-loop pitch table. Phase 2 used the simulated nominal and three simulated off nominal runs to tune the open-loop pitch table. Phase 3 used the simulated nominal and sixteen simulated off nominal runs to tune the open-loop pitch table. The optimization program allowed for a quicker and more accurate fit to the desired profile as well as allowing for expanded resolution of the pitch table.

Stillwater, Ryan A.↗
NASA NTRS2011

Achieving Maximum Integration Utilizing Requirements Flow Down

A robust and experienced systems engineering team is essential for a successful program. It is often a challenge to build a core systems engineering team early enough in a program to maximize integration and assure a common path for all supporting teams in a project. Ares I was no exception. During the planning of IVGVT, the team had many challenges including lack of: early identification of stakeholders, team training in NASA s system engineering practices, solid requirements flow down and a top down documentation strategy. The IVGVT team started test planning early in the program before the systems engineering framework had been matured due to an aggressive schedule. Therefore the IVGVT team increased their involvement in the Constellation systems engineering effort. Program level requirements were established that flowed down to IVGVT aligning all stakeholders to a common set of goals. The IVGVT team utilized the APPEL REQ Development Management course providing the team a NASA focused model to follow. The IVGVT team engaged directly with the model verification and validation process to assure that a solid set of requirements drove the need for the test event. The IVGVT team looked at the initial planning state, analyzed the current state and then produced recommendations for the ideal future state of a wide range of systems engineering functions and processes. Based on this analysis, the IVGVT team was able to produce a set of lessons learned and to provide suggestions for future programs or tests to use in their initial planning phase.

Archiable, Wes↗