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At least 1,207 records · Page 67

Transcription factor IID in the Archaea: sequences in the Thermococcus celer genome would encode a product closely related to the TATA-binding protein of eukaryotes

The first step in transcription initiation in eukaryotes is mediated by the TATA-binding protein, a subunit of the transcription factor IID complex. We have cloned and sequenced the gene for a presumptive homolog of this eukaryotic protein from Thermococcus celer, a member of the Archaea (formerly archaebacteria). The protein encoded by the archaeal gene is a tandem repeat of a conserved domain, corresponding to the repeated domain in its eukaryotic counterparts. Molecular phylogenetic analyses of the two halves of the repeat are consistent with the duplication occurring before the divergence of the archael and eukaryotic domains. In conjunction with previous observations of similarity in RNA polymerase subunit composition and sequences and the finding of a transcription factor IIB-like sequence in Pyrococcus woesei (a relative of T. celer) it appears that major features of the eukaryotic transcription apparatus were well-established before the origin of eukaryotic cellular organization. The divergence between the two halves of the archael protein is less than that between the halves of the individual eukaryotic sequences, indicating that the average rate of sequence change in the archael protein has been less than in its eukaryotic counterparts. To the extent that this lower rate applies to the genome as a whole, a clearer picture of the early genes (and gene families) that gave rise to present-day genomes is more apt to emerge from the study of sequences from the Archaea than from the corresponding sequences from eukaryotes.

NASA Discipline Exobiology↗

Increasing Access and Usability of Remote Sensing Data: The NASA Protected Area Archive

Although remote sensing data are now widely available, much of it at low or no-cost, many managers of protected conservation areas do not have the expertise or tools to view or analyze it. Thus access to it by the protected area management community is effectively blocked. The Protected Area Archive will increase access to remote sensing data by creating collections of satellite images of protected areas and packaging them with simple-to-use visualization and analytical tools. The user can easily locate the area and image of interest on a map, then display, roam, and zoom the image. A set of simple tools will be provided so the user can explore the data and employ it to assist in management and monitoring of their area. The 'Phase 1 ' version requires only a Windows-based computer and basic computer skills, and may be of particular help to protected area managers in developing countries.

remote sensing↗

Single Event Rates for Devices Sensitive to Particle Energy

Single event rates (SER) can include contributions from low-energy particles such that the linear energy transfer (LET) is not constant. Previous work found that the environmental description that is most relevant to the low-energy contribution to the rate is a "stopping rate per unit volume" even when the physical mechanisms for a single-event effect do not require an ion to stop in some device region. Stopping rate tables are presented for four heavy-ion environments that are commonly used to assess device suitability for space applications. A conservative rate estimate utilizing limited test data is derived, and the example of SEGR rate in a power MOSFET is presented.

conservative rate↗

A Preliminary Study on the Use of a NASA Developed Coatings Technology for Protecting Natural Science Collections from Molecular Contaminants

Many museum conservators and collection managers are faced with the challenge of molecular contaminants that can promote the degradation of specimens on display in exhibits or in cabinets at storage facilities. This has prompted the need to explore innovative techniques to alleviate the presence of chemical species that originate from atmospheric off-gassing of materials or cross-contamination among collection items. For example, the Smithsonian Institution's National Museum of Natural History (NMNH) has tackled this problem for many years, specifically targeting contaminants, such as mercury vapor, at its Museum Support Center (MSC) storage facility in Suitland, Maryland. Similarly, the presence of molecular contaminants poses a significant threat for NASA science and exploration missions. The deposition of chemical species on sensitive surfaces can degrade the performance and operational lifetime of satellites, telescopes, and instruments. As a result, a sprayable zeolite-based coatings technology was designed to passively capture molecular contaminants and reduce the risks associated with material outgassing in vacuum environments for aerospace applications. This technology, called the Molecular Adsorber Coating (MAC), was developed at NASA Goddard Space Flight Center (GSFC). MAC has been extensively used during thermal vacuum chamber testing of various spaceflight hardware and components, such as for the James Webb Space Telescope (JWST). The coating is also planned to fly aboard upcoming NASA missions to address on-orbit outgassing concerns within instrument and laser cavities. Recently, the MAC technology was evaluated as a possible solution for protecting the Smithsonian Institution's natural science specimens, specifically its mineral ore and botany collections at the MSC storage facility. The initial year-long study between NASA GSFC and NMNH involved investigating the effectiveness of the MAC technology in capturing molecular contaminants that are present within the collections and storage cabinets at ambient, non-vacuum conditions. The work included sample fabrication, installation and retrieval efforts, testing efforts and associated challenges, preliminary findings, and future plans for the multi-year project.

conservation↗

High-resolution Wave Propagation Method for Stratified Flows

The implementation of the multidimensional f-waves Riemann solver for the time-dependent, three-dimensional, nonhydrostatic, meso- and microscale atmospheric flows is described in detail. The Riemann solver employs flux-based wave decomposition (f-waves) for the calculation of Godunov fluxes in which the flux differences are written directly as the linear combination of the right eigenvectors of the hyperbolic system. The scheme incorporates the source term due to gravity without introducing discretization errors which is an important property in the context of atmospheric flows. The resulting flow solver is conservative, accurate, stable, and well-balanced. The implementation of the solver is evaluated using benchmark test cases for atmospheric dynamics.

Riemann problem↗

Mass Mitigation in Structural Designs Via Dynamic Properties

The efforts reported here are focused on mitigating unnecessary mass in aerospace hardware. The approach to remove this undesired mass from the design is to leverage both the dynamic strength of materials and the frequency dependency of strain. Analytically predicted dynamic responses of structures are often applied as static loads in stress analyses that ultimately dictate the weight of a structural design. Assuming a dynamic response is a static load and then comparing resulting stress predictions to a static strength property is a long-standing engineering practice. Doing so is known to be, or is assumed to be, conservative. However, little indication of the order of magnitude of embedded conservatism has been identified. NASA/MSFC efforts in 2011, 2019, 2020, and now in 2021 have begun to qualitatively show the order of magnitude of that conservatism. A quick turnaround engineering method is pursued to leverage the subject facets of physics for the purpose of decreasing the weight of flight hardware. Tests performed using simple beams and significant observations are described.

conservative design loads↗

Undue Conservatisim in Structural Designs

Assuming that dynamic (transient/vibratory) loads are static in the design of structures is a long-standing engineering practice. The assumption is conservative for hardware that will have limited exposure to the specified dynamic environment and fatigue is not a concern. This is the case for most space flight hardware. Once out of the Earth’s atmosphere, significant vibrations are non-existent for most hardware and vibration cycles are limited. Mass is, and has always been, a concern with respect to flight hardware design. How much unnecessary mass due to the subject assumption may be in structural designs was questioned and numerous tests have been performed to qualitatively address that. Tests have been performed on simple aluminum beams, beams with bolted joints and beams with welded joints. Results of those tests are reported in this paper. The objective of these efforts was to demonstrate the order of magnitude of conservatism associated with this engineering process via comparing static to dynamic tests and the longer term endgame is to develop a new or modified quick turnaround structural design process that circumvents assuming dynamic loads are static and results in lighter structural designs. Test results qualitatively demonstrate notable conservatism. Activities to devise the new method are underway.

conservative loads↗

Carbon Dioxide Reduction Systems

The Methoxy system for regenerating oxygen from carbon dioxide was studied. Experiments indicate that the reaction between carbon dioxide and hydrogen can be carried out with ease in an efficient manner and with excellent heat conservation. A small reactor capable of handling the C02 expired by three men has been built and operated. The decomposition of methane by therma1,arc and catalytic processes was studied. Both the arc and catalytic processes gave encouraging results with over 90 percent of the methane being decomposed to carbon and hydrogen in some of the catalytic processes. Control of the carbon deposition in both the catalytic and arc processes is of great importance to prevent catalyst deactivation and short circuiting of electrical equipment. Sensitive analytical techniques have been developed for all of the components present in the reactor effluent streams.

METHOXY SYSTEM↗

Experience with Mercury Spacecraft Systems

Design of a manned spacecraft in 1958 and 1959 required that many decisions be made with no background of direct experience with similar vehicles and very little background of experience on vehicles of any type which had been exposed to the rigors of space. Under such circumstances, it was necessary to establish certain fundamental design principles which were believed to represent the proper balance between the conservatism required by the unknowns, the desired development schedule, and the extreme necessity to conserve weight. One of the foremost of the program objectives was, of course, safety. Broadly speaking, the design principles chosen to achieve the level of safety desired in such an unknown venture were very similar to those used for manned aircraft design.

Spacecraft↗

Advanced Environmental Systems

Atmosphere controls for advanced manned space vehicles will in some cases require techniques different from those selected as optimum for the Mercury environmental control system (ECS). Water conservation will be rigorous for vehicles which use a solar or nuclear auxiliary power unit (APU). For missions longer than a few hundred hours, CO2 will be removed in a regenerable process. Several promising regenerable CO2 removal systems are presented, including freeze-out. Regeneration of oxygen from C02 is discussed as the next step in atmosphere control advancement. Test work on CO2 hydrogenation by the Sabatier process is cited. The recommended makeup of ECS elements is presented as a function of mission duration.

Manned spacecraft↗

SOME TYPICAL SHELL STABILITY PROBLEMS ENCOUNTERED IN THE DESIGN OF BALLISTIC MISSILES

Investigations carried out at STL on three current problems involving instability of thin shells in applications to aerospace vehicles are discussed. The first concerns the experimental determination of the buckling behavior of longitudinally stiffened pressurized cylinders; the second, the analytic prediction and experimental confirmation of the buckling behavior of multi-layer cylinders and the third involves the behavior of cylinders under combined axial load and lateral pressure. In each case the background of the application is reviewed, followed by a short description of the work. It is indicated that the longitudinally stiffened cylinder shows considerable promise in taking maximum advantage of the strengthening effect of internal pressure, that the use of an external low modulus layer as an insulator can have a significant effect on the buckling capability of a shell, and that the assumption of a linear interaction for pressure and axial load is unnecessarily conservative.

SHELL STABILITY↗

BUCKLING OF CONICAL SHELLS UNDER EXTERNAL PRESSURE

It is shown that the initial and the buckled shapes of a certain element of a conical shell can be considered as similar to those of an element of a cylindrical shell of which the radius and length are conservatively determined. It is concluded that therefore the buckling pressure of the conical shell is equal to that of the comparable cylindrical shell. A simple method for finding the buckling pressure if it varies along a generatrix is also given.

CONICAL SHELL↗

CONVECTION IN PLANETARY INTERIORS

Formulation of linearized equations safeguarding the conservation of mass, energy and momentum of viscous flow inside a fluid sphere, and application to the problem of convection in planetary interiors

VISCOUS FLOW↗

ASTRORELATIVITY

Relativity theory applied to conservation laws of momentum and total energy of rockets

RELATIVITY THEORY↗

Quick-acting clutch disengages idle drive motor

Positive-drive, no drag, over-running clutch is developed to conserve power of idle motor in a low-power system using multiple drive motors. This device is useful where a number of shaft speeds are required with frequent shifting.

Stark, K. W.↗

The spacecraft power supply system

The power supply system in the Telstar spacecraft consists of a solar cell plant to convert solar radiation to electrical energy when the satellite is illuminated by the sun, a 19-cell nickel-cadmium battery to store energy, and a regulation circuit to supply constant output voltages over a wide variation in input voltages. Additionally, the power supply system provides switching to conserve power and allow battery recharging during periods between communications experiments.

POWER SUPPLY↗