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Search indexed NASA NTRS and DOE OSTI research on propulsion, heat transfer, battery materials and energy systems. Follow report and document links to the original sources.

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At least 1,207 records · Page 67
All sourcesNASA NTRSDOE OSTI
DOE OSTI2025

NADH-bound AIF activates the mitochondrial CHCHD4/MIA40 chaperone by a substrate-mimicry mechanism

Mitochondrial metabolism requires the chaperoned import of disulfide-stabilized proteins via CHCHD4/MIA40 and its enigmatic interaction with oxidoreductase Apoptosis-inducing factor (AIF). By crystallizing human CHCHD4’s AIF-interaction domain with an activated AIF dimer, we uncover how NADH allosterically configures AIF to anchor CHCHD4’s β-hairpin and histidine-helix motifs to the inner mitochondrial membrane. The structure further reveals a similarity between the AIF-interaction domain and recognition sequences of CHCHD4 substrates. NMR and X-ray scattering (SAXS) solution measurements, mutational analyses, and biochemistry show that the substrate-mimicking AIF-interaction domain shields CHCHD4’s redox-sensitive active site. Disrupting this shield critically activates CHCHD4 substrate affinity and chaperone activity. Regulatory-domain sequestration by NADH-activated AIF directly stimulates chaperone binding and folding, revealing how AIF mediates CHCHD4 mitochondrial import. These results establish AIF as an integral component of the metazoan disulfide relay and point to NADH-activated dimeric AIF as an organizational import center for CHCHD4 and its substrates. Importantly, AIF regulation of CHCHD4 directly links AIF’s cellular NAD(H) sensing to CHCHD4 chaperone function, suggesting a mechanism to balance tissue-specific oxidative phosphorylation (OXPHOS) capacity with NADH availability.

Brosey, Chris A↗
NASA NTRS1999

Comparisons of the Vertical Development of Deep Tropical Convection and Associated Lightning Activity on a Global Basis

Simultaneous radar (13.8 Ghz) and lightning (Lightning Imaging Sensor) observations from the NASA TRMM (Tropical Rainfall Measuring Mission) spacecraft afford a new opportunity to examine differences in tropical continental and oceanic convection on a global basis, The 250 meter vertical resolution of the radar data and the approximately 17 dBZ sensitivity are well suited to providing vertical profiles of radar reflectivity over the entire tropical belt. The reflectivity profile has been shown in numerous local ground-based studies to be a good indicator of both updraft velocity and electrical activity. The radar and lightning observations for multiple satellite orbits have been integrated to produce global CAPPI's for various altitudes. At 7 km altitude, where mixed phase microphysics is known to be active, the mean reflectivity in continental convection is 10-15 dB greater than the value in oceanic convection. These results provide a sound physical basis for the order-of-magnitude contrast in lightning counts between continental and oceanic convection. These observations still beg the question, however, about the contrast in updraft velocity in these distinct convective regimes.

Williams, E.↗
NASA NTRS2005

Effects of Volcanoes on the Natural Environment

The primary focus of this project has been on the development of techniques to study the thermal and gas output of volcanoes, and to explore our options for the collection of vegetation and soil data to enable us to assess the impact of this volcanic activity on the environment. We originally selected several volcanoes that have persistent gas emissions and/or magma production. The investigation took an integrated look at the environmental effects of a volcano. Through their persistent activity, basaltic volcanoes such as Kilauea (Hawaii) and Masaya (Nicaragua) contribute significant amounts of sulfur dioxide and other gases to the lower atmosphere. Although primarily local rather than regional in its impact, the continuous nature of these eruptions means that they can have a major impact on the troposphere for years to decades. Since mid-1986, Kilauea has emitted about 2,000 tonnes of sulfur dioxide per day, while between 1995 and 2000 Masaya has emotted about 1,000 to 1,500 tonnes per day (Duffel1 et al., 2001; Delmelle et al., 2002; Sutton and Elias, 2002). These emissions have a significant effect on the local environment. The volcanic smog ("vog" ) that is produced affects the health of local residents, impacts the local ecology via acid rain deposition and the generation of acidic soils, and is a concern to local air traffic due to reduced visibility. Much of the work that was conducted under this NASA project was focused on the development of field validation techniques of volcano degassing and thermal output that could then be correlated with satellite observations. In this way, we strove to develop methods by which not only our study volcanoes, but also volcanoes in general worldwide (Wright and Flynn, 2004; Wright et al., 2004). Thus volcanoes could be routinely monitored for their effects on the environment. The selected volcanoes were: Kilauea (Hawaii; 19.425 N, 155.292 W); Masaya (Nicaragua; 11.984 N, 86.161 W); and Pods (Costa Rica; 10.2OoN, 84.233 W).

Mouginis-Mark, Peter J.↗
DOE OSTI2024

Thermodynamic control on the decomposition of organic matter across different electron acceptors

The increasing availability of high-resolution characterization of natural organic matter (OM) data has shifted the paradigm of lumped descriptions of OM components and potential microbial activities. Our recent development of a substrate-explicit thermodynamic model uniquely enables incorporating complex OM pools to formulate biogeochemical reaction models based on their elemental compositions. While this previous work facilitates prediction of aerobic respiration of complex OM, it is equally imperative to consider the role of non-oxygenic electron acceptors in regulating OM turnover and the fate of carbon. In this study, we significantly expand our previous model by flexibly incorporating both detailed OM chemistry and electron acceptors other than oxygen. Here, our modeling analysis has revealed substantial variations in the energy status of OM molecules across different soils, which drive the co-occurrence of different electron-accepting processes. We demonstrated the effectiveness of the proposed model using a consistency check with experimental data. Through systematic evaluation of the impact of diverse chemical inputs (both electron donors and acceptors) on OM decomposition, the new model also revealed how key microbial growth parameters such as carbon use efficiency (CUE) and reaction rates vary across different electron-accepting processes. Our model provides a unified framework integrating thermodynamic and kinetic constraints on microbial metabolic activities. It complements traditional kinetic models, which are often designed solely to capture mass fluxes. We conclude that thermodynamic modeling emerges as a powerful tool for describing the mechanisms underlying the interplay between microbial growth and OM chemistry and cycling across different electron acceptors, enhancing our ability to project complex ecosystem behaviors in dynamic environments.

59 BASIC BIOLOGICAL SCIENCES↗
NASA NTRS2015

The JWST Science Instrument Payload: Mission Context and Status

The James Webb Space Telescope (JWST) is the scientific successor to the Hubble Space Telescope. It is a cryogenic infrared space observatory with a 25 sq m aperture (6 m class) telescope that will achieve diffraction limited angular resolution at a wavelength of 2 micrometers. The science instrument payload includes four passively cooled near-infrared instruments providing broad- and narrow-band imagery, coronography, as well as multi-object and integral-field spectroscopy over the 0.6 is less than lambda is less than 5.0 micrometers spectrum. An actively cooled mid-infrared instrument provides broad-band imagery, coronography, and integral-field spectroscopy over the 5.0 is less than lambda is less than 29 micrometers spectrum. The JWST is being developed by NASA, in partnership with the European and Canadian Space Agencies, as a general user facility with science observations proposed by the international astronomical community in a manner similar to the Hubble Space Telescope. Technology development and mission design are complete. The science instrument payload is in the final stage of testing ahead of delivery for integration with the telescope during early 2016. The JWST is on schedule for launch during 2018.

narrow-band imagery↗
NASA NTRS2016

Managing a Safe and Successful Multi-User Spaceport

Encouraged by the creation of the Office of Commercial Space Transportation within the U.S. Federal Aviation Administration (FAA) in 1984 and the Commercial Space Act of 1998, the National Aeronautics and Space Administration (NASA) now relies on an extensive network of support from commercial companies and organizations. At NASA's Kennedy Space Center (KSC), this collaboration opens competitive opportunities for launch providers, including repurposing underutilized Shuttle Program resources, constructing new facilities, and utilizing center services and laboratories. The resulting multi-user spaceport fosters diverse activity, though it engenders risk from hazards associated with various spaceflight processing activities. The KSC Safety & Mission Assurance (S&MA) Directorate, in coordination with the center's Spaceport Integration and Center Planning & Development organizations, has developed a novel approach to protect NASA's workforce, critical assets, and the public from hazardous, space-related activity associated with KSC's multi-user spaceport. For NASA KSC S&MA, the transformation to a multi-user spaceport required implementing methods to foster safe and successful commercial activity while resolving challenges involving: Retirement of the Space Shuttle program; Co-location of multiple NASA programs; Relationships between the NASA programs; Complex relationships between NASA programs and commercial partner operations in exclusive-use facilities; Complex relationships between NASA programs and commercial partner operations in shared-use facilities. NASA KSC S&MA challenges were met with long-term planning and solutions involving cooperation with the Spaceport Integration and Services Directorate. This directorate is responsible for managing active commercial partnerships with customer advocacy and services management, providing a dedicated and consistent level of support to a wide array of commercial operations. This paper explores these solutions, their relevance to the current commercial space industry, and the challenges that continue to drive improvement with a focus on areas of safety management and risk assessment that have been crucial in KSC's evolution into a multi-user spaceport. These solutions may be useful to government entities and private companies looking to partner with the commercial space industry.

Range↗
NASA NTRS1986

MMIC devices for active phased array antennas

The use of finlines for microwave monolithic integrated circuit application in the 20 to 40 GHz frequency range. Other wave guiding structures, are also examined from a comparative point of view and some sonclusions are drawn on the basis of the results.

Mittra, R.↗
NASA NTRS1992

Planar dielectric resonator stabilized HEMT oscillator integrated with CPW/aperture coupled patch antenna

A new design of an active antenna with a dielectric resonator stabilized high electron mobility transistor (HEMT) oscillator (DRO) and an aperture-coupled patch antenna is reported. The circuit is fabricated using coplanar waveguide (CPW) with the oscillator and the antenna on opposite sides of the substrate. The active antenna was demonstrated at 7.6 GHz; however, the design can be scaled to higher frequencies. Excellent oscillator characteristics and radiation patterns were obtained.

Simons, Rainee N.↗
DOE OSTI2021

High resistivity iron-based, thermally stable magnetic material for on-chip integrated inductors

An on-chip magnetic structure includes a palladium activated seed layer and a substantially amorphous magnetic material disposed onto the palladium activated seed layer. The substantially amorphous magnetic material includes nickel in a range from about 50 to about 80 atomic % (at. %) based on the total number of atoms of the magnetic material, iron in a range from about 10 to about 50 at. % based on the total number of atoms of the magnetic material, and phosphorous in a range from about 0.1 to about 30 at. % based on the total number of atoms of the magnetic material. The magnetic material can include boron in a range from about 0.1 to about 5 at. % based on the total number of atoms of the magnetic material.

Deligianni, Hariklia↗
DOE OSTI2023

Management and International Sorption Model Collaboration (M4SF-23LL010302062-NEA-TDB)

This progress report (Level 4 Milestone Number M4SF-23LL010302062) summarizes research conducted at Lawrence Livermore National Laboratory (LLNL) within the Crystalline International Collaborations Activity Number SF-23LL01030206. The activity is focused on our long-term commitment of engaging our partners in international nuclear waste repository research. This includes participation in the Nuclear Energy Agency Thermochemical Database (NEA-TDB) Project and development of methodologies for integrating US and international thermodynamic databases for use in SFWST Generic Disposal System Assessment (GDSA) efforts. A continuing focus for FY23 efforts has been to support the US participation in the NEA-TDB effort (Mavrik Zavarin replaced Cindy Atkins-Duffin on the NEA-TDB Management Board (MB) and Executive Group (EG)) and developing mechanisms for integration of NEA-TDB thermochemical data with LLNL’s SUPCRTNE thermodynamic database that supports the SFWST GDSA activities. This effort is coordinated with the Argillite work package SUPCRTNE database development efforts. The goal is to provide a downloadable database that will be hosted on a LLNL website which integrates NEA-TDB data into the LLNL SUPCRTNE database where appropriate. As part of our international activities, we continue our effort to integrate international sorption databases into L-SCIE (Zavarin et al., 2022b). We presented opportunities to include sorption in the next phase of NEA-TDB efforts at the April 2023 EG meeting in Paris. FY23 efforts focused on ensuring interoperable database development across multiple international database development activities. The overall goal is to produce an open source database that can be shared and integrated with multiple nuclear waste programs internationally and harness modern data science workflows and algorithms to incorporate these new approaches into reactive transport and performance assessment models. In collaboration with our Helmholtz Zentrum Dresden Rossendorf partners, we recently demonstrated the power of FAIR open source databases by fitting iron oxide (hydrous ferric oxide, goethite, hematite, and magnetite) protolysis constants to all available L-SCIE data. The results were submitted as a manuscript to J. Colloid Interface Science. This work will inform future metal sorption studies on a variety of iron oxides in order to discern the most appropriate acidity constants and surface complexation modeling constructs to account for pH-dependent mineral surface charge behavior. This work also explored automated surface complexation model development workflows in order to generate higher throughput model input files for a more facile incorporation into GDSA activities.

38 RADIATION CHEMISTRY, RADIOCHEMISTRY, AND NUCLEA↗
DOE OSTI2023

Adaptive, Active Learning, and Multifidelity Monte Carlo Methods in the MOOSE Stochastic Tools Module

MOOSE is an open-source computational platform for constructing multi-physics models and executing them in a massively parallel fashion. It has a stochastic tools module (STM) for forward/inverse uncertainty quantification (UQ) and surrogate modeling. This presentation details some recent developments to the STM with respect to the implementation of adaptive, active learning, and multifidelity Monte Carlo methods for forward UQ of computational models. Specifically, the adaptive Monte Carlo methods include Markov Chain Monte Carlo (MCMC)-driven algorithms like adaptive importance sampling and parallelized subset simulation for statistical QoI estimation, rare events analysis, and stochastic gradient-free optimization. The active learning methods include Gaussian Process (GP) surrogates and their training via Adam optimization, design of acquisition functions, and integration with samplers like Monte Carlo, adaptive importance, and parallelized subset simulation. These active learning methods are also designed to work in a batch mode, wherein, the required calls to the full computational model are executed in parallel whenever a user-specified batch size is met. The multifidelity methods in STM are broadly divided into two categories: hierarchical, where a defined hierarchy exists among the low-fidelity models, and peer, where all the low-fidelity models are treated equally. A GP surrogate is used to learn the differences between the low- and high-fidelity models in both multifidelity categories, and acquisition functions from the active learning classes are used to decide whether to rely on a low-fidelity model or call the expensive high-fidelity model. Alongside the software description and usage, applications are also presented to nuclear engineering computational models including a TRISO nuclear fuel particle, a reactor pressure vessel, and a heat-pipe microreactor.

97 MATHEMATICS AND COMPUTING↗
DOE OSTI2020

Selection of Components for the Remote, Canister-Monitoring System

This report documents the selection of components as part of the efforts initiated to develop a remote, canister-monitoring system (RCMS) for determining and monitoring environmental conditions within dry fuel storage canisters containing aluminum clad spent nuclear fuel (ASNF) at the Idaho National Laboratory (INL). These efforts are in support of Department of Energy Office of Environmental Management (DOE-EM) investigations into technical issues associated with extended dry storage (50+ years) of ASNF. The capability to establish and monitor the performance of ASNF in situ provides the opportunity to (1) evaluate the appropriate technologies for monitoring, (2) collect canister environment conditions as soon as possible, (3) verify and validate current laboratory-based study results and analytic modeling approaches, and (4) potentially identify additional dry storage options for ASNF at the INL site. The improved understanding of ASNF behavior gained by performing this work would also contribute to the safety basis for extended dry storage in current and future configurations as well as to provide information for future transportation, conditioning, and disposal of ASNF. The parameters to be monitored by the RCMS include temperature, relative humidity, hydrogen gas concentration and radiation environment (dose). Components are selected based on the expected environmental conditions within the canister and fuel storage area, and the desired performance of the RCMS. Several of these components have been purchased and received. Future activities include component testing and calibration, software development for operation of the integrated sensor module and fabrication of a representative test volume. The results of these tests and changes to desired performance characteristics will inform subsequent activities.

11 NUCLEAR FUEL CYCLE AND FUEL MATERIALS↗
NASA NTRS1991

SEEDS: A Celebration of Science

The major goal of the project of Space Exposed Experiment Developed for Students (SEEDS) was to stimulate interest in science through the active involvement of all participants. Youthful investigators utilized the basic and integrated science process skills as they conducted the research necessary to complete the data reports used in the compilation of this document. Participants described many unique activities designed to promote critical thinking and problem solving. Seeds made a significant impact toward enhancing the teaching, learning, and enjoyment of science for students worldwide.

Melton, Bob↗
NASA NTRS2022

NESC Peer Review of Exploration Systems Development (ESD) Integrated Vehicle Modal Test, Model Correlation, Development Flight Instrumentation (DFI) and Flight Loads Readiness; Uncertainty Propagation for Model Validation Sub-task

This report details a sub-task (regarding Uncertainty Propagation for Model Validation) from a NASA Engineering and Safety Center assessment that is a multi-year activity spanning the complete development of the Space Launch System integrated vehicle structural dynamic models, and the development of the certification of flight readiness for the Artemis 1 and Artemis 2 vehicles and their variants.

Exploration Systems Development; Development Fligh↗
NASA NTRS1972

Shuttle free-flying teleoperator system experiment definition. Volume 3: program development requirements

The planning data are presented for subsequent phases of free-flying teleoperator program (FFTO) and includes costs, schedules and supporting research and technology activities required to implement the free-flying teleoperator system and associated flight equipment. The purpose of the data presented is to provide NASA with the information needed to continue development of the FFTO and integrate it into the space shuttle program. The planning data describes three major program phases consisting of activities and events scheduled to effect integrated design, development, fabrication and operation of an FFTO system. Phase A, Concept Generation, represents a study effort directed toward generating and evaluating a number of feasible FFTO experiment system concepts. Phase B, Definition, will include preliminary design and supporting analysis of the FFTO, the shuttle based equipment and ground support equipment. Phase C/D, Design, Development and Operations will include detail design of the operational FFTO, its integration into the space shuttle, hardware fabrication and testing, delivery of flight hardware and support of flight operations. Emphasis is placed on the planning for Phases A and B since these studies will be implemented early in the development cycle. Phase C/D planning is more general and subject to refinement during the definition phase.

Source record↗
NASA NTRS2000

Space Solar Power Multi-body Dynamics and Controls, Concepts for the Integrated Symmetrical Concentrator Configuration

Orbiting space solar power systems are currently being investigated for possible flight in the time frame of 2015-2020 and later. Such space solar power (SSP) satellites are required to be extremely large in order to make practical the process of collection, conversion to microwave radiation, and reconversion to electrical power at earth stations or at remote locations in space. These large structures are expected to be very flexible presenting unique problems associated with their dynamics and control. The purpose of this project is to apply the expanded TREETOPS multi-body dynamics analysis computer simulation program (with expanded capabilities developed in the previous activity) to investigate the control problems associated with the integrated symmetrical concentrator (ISC) conceptual SSP system. SSP satellites are, as noted, large orbital systems having many bodies (perhaps hundreds) with flexible arrays operating in an orbiting environment where the non-uniform gravitational forces may be the major load producers on the structure so that a high fidelity gravity model is required. The current activity arises from our NRA8-23 SERT proposal. Funding, as a supplemental selection, has been provided by NASA with reduced scope from that originally proposed.

Glaese, John R.↗
DOE OSTI2026

Ampk alpha2 T172 activation dictates exercise performance and energy transduction in skeletal muscle

Adenosine 5′-monophosphate–activated protein kinase (AMPK) is an energetic sensor for metabolic regulation and integration. Here, we used CRISPR-Cas9 to generate nonactivatable Ampkα knock-in (KI) mice with mutation of threonine-172 phosphorylation site to alanine (T172A), circumventing the limitations of previous genetic interventions that disrupt the protein stoichiometry. KI mice of Ampkα2, but not Ampkα1, demonstrated phenotypic changes with increased fat-to-lean mass, impaired endurance exercise capacity, and diminished mitochondrial maximal respiration and conductance in skeletal muscle. Integrated temporal multiomics analysis (proteomics/phosphoproteomics/metabolomics) in skeletal muscle at rest and during exercise establishes a pleiotropic yet imperative role of Ampkα2 T172 activation for glycolytic and oxidative metabolism, mitochondrial respiration, and contractile function. There is a substantial overlap of skeletal muscle proteomic changes in Ampkα2 T172A KI mice with that of patients with type 2 diabetes. Our findings suggest that Ampkα2 T172 activation is critical for exercise performance and energy transduction in skeletal muscle and may serve as a therapeutic target for type 2 diabetes.

Bioenergetics↗