Engineering Papers⌕ Search

SEARCH · Engineering Papers

Results for “STIMULATION”

Search indexed NASA NTRS and DOE OSTI research on propulsion, heat transfer, battery materials and energy systems. Follow report and document links to the original sources.

Quote a phrase for an exact phrase match. Source license links do not imply unrestricted reuse.

At least 1,189 records · Page 66

Electrotactile and vibrotactile displays for sensory substitution systems

Sensory substitution systems provide their users with environmental information through a human sensory channel (eye, ear, or skin) different from that normally used or with the information processed in some useful way. The authors review the methods used to present visual, auditory, and modified tactile information to the skin and discuss present and potential future applications of sensory substitution, including tactile vision substitution (TVS), tactile auditory substitution, and remote tactile sensing or feedback (teletouch). The relevant sensory physiology of the skin, including the mechanisms of normal touch and the mechanisms and sensations associated with electrical stimulation of the skin using surface electrodes (electrotactile, or electrocutaneous, stimulation), is reviewed. The information-processing ability of the tactile sense and its relevance to sensory substitution is briefly summarized. The limitations of current tactile display technologies are discussed.

Kaczmarek, Kurt A.↗

Cosmos-1989 immunology studies

Evidence from both human and rodent studies has indicated that alterations in immunological parameters occur after space flight. The number of flight experiments has been small, and the full breadth of immunological alterations occurring after space flight remains to be established. Among the major effects on immune responses after space flight that have been reported are: alterations in lymphocyte blastogenesis and natural killer cell activity, alterations in production of cytokines, changes in leukocyte sub-population distribution, and decreases in the ability in the ability of bone marrow cells to respond to colony stimulating factors. Changes have been reported in immunological parameters of both humans and rodents. The significance of these alterations in relation to resistance to infection remains to be established. The current study involved a determination of the effects of flight on Cosmos mission 2044 on leukocyte subset distribution and the sensitivity of bone marrow cells to colony stimulating factor-GM. A parallel study with antiorthostatic suspension was also carried out. The study involved repetition and expansion of studies carried out on Cosmos 1887.

Sonnenfeld, Gerald↗

Theoretical studies of lasers and converters

Discussed here is Doppler broadening and its effects upon the stimulated emission cross-section connecting an upper level with a lower level in an iodine laser. The stimulated emission cross section is given. The level transitions for the iodine laser are illustrated as are the relative intensities of these transitions. Also discussed is the Voigt profile, which considers the effect of both Doppler broadening and collision broadening upon the absorption line shape. The equations describing the Voigt profile were added to the continuous flow laser model laser simulation program. The results were compared with the standard absorption profile reported in an earlier study. There seems to be no advantage to using the Voigt profile as the laser power output is relatively insensitive to changes in the absorption cross section at the pressures being considered for a space laser. One disadvantage of using the Voigt profile is the excessive numerical computations required by the additional equations.

Heinbockel, John H.↗

Atomic oxygen effects on thermal control and mirror coatings: Evaluation of experiment A0034

Evaluation of the degradation attributed to contamination of the collector mirrors in Experiment A0034, which were exposed to an earth orbital environment while on the leading and trailing edges of the LDEF, has provided some evidence for outgassing of coatings stimulated by atomic oxygen. Effects of the natural space environment on the coatings and mirrors, including the effects of incident and re-directed atomic oxygen flux, were investigated. The effects of exposure on the coatings and mirrors were evaluated by optical, surface profiling, chemical, and scanning electron microscopy (SEM) measurements. Preliminary results of these analyses are discussed for application to both the issues of mirror and coating stability and the specific issue of atomic oxygen stimulated outgassing.

Linton, Roger C.↗

Effects of microgravity on the immune system

Changes in resistance to bacterial and viral infections in Apollo crew members has stimulated interest in the study of immunity and space flight. Results of studies from several laboratories in both humans and rodents have indicated alterations after space flight that include the following immunological parameters: thymus size, lymphocyte blastogenesis, interferon and interleukin production, natural killer cell activity, cytotoxic T-cell activity, leukocyte subset population distribution, response of bone marrow cells to colony stimulating factors, and delayed hypersensitivity skin test reactivity. The interactions of the immune system with other physiological systems, including muscle, bone, and the nervous system, may play a major role in the development of these immunological parameters during and after flight. There may also be direct effects of space flight on immune responses.

Sonnenfeld, Gerald↗

Observation and theory of the barium releases from the CRRES satellite

The relationship between releases of barium from the NASA Combined Release and Radiation Effects Satellite (CRRES) and enhanced auroral activity is discussed with reference to observational data. Barium releases were conducted at a variety of altitudes and injection velocities, and plasma irregularities are reported as a result of the interactions. Auroral activity increased within 5 min of each release, and references are made to the effects on diamagnetic cavities, bulk ion motion, and stimulated electron and ion precipitation. Artificially created structured diamagnetic cavities are noted for each release, plasma waves are generated by the high-speed ion clouds, and enhanced ionization is found in the critical ionization-velocity process. Barium releases are effective in stimulating electron precipitation, and the observed irregularities are related to cycloid bunching of the initial ion distributions.

Bernhardt, P. A.↗

Effects of space exposure on thermal control coatings

Optical degradation of selected thermal control coatings exposed on LDEF Experiment A0034, 'Atomic Oxygen Stimulated Outgassing', attributable to effects of solar radiation, was significantly changed for specimens whose exposure included orbital atomic oxygen impingement. This LDEF experiment consisted of two passive modules, one exposed to the total space environment on the Leading Edge (RAM) and another exposed to the relative wake of the Trailing Edge. Evidence of atomic oxygen stimulated outgassing and the interrelated effects of the natural environment based on evaluation of the flight specimens will be discussed.

Linton, Roger C.↗

Gravitropism in higher plant shoots. I - A role for ethylene

Two inhibitors of ethylene synthesis, Co(2+) and aminoethoxyvinylglycine (AVG), and two inhibitors of ethylene action, Ag(+) and CO2, are shown to delay the gravitropic response of cocklebur (Xanthium strumarium L.), tomato (Lycopersicon esculentum Mill.), and castor bean (Ricinus communis L.) stems. Gentle shaking on a mechanical shaker does not inhibit the gravitropic response, but vigorous hand shaking for 120 seconds delays the response somewhat. AVG and Ag(+) further delay the response of mechanically stimulated plants. AVG retards the storage of bending energy but not of stimulus. In gravitropism, graviperception may first stimulate ethylene evolution, which may then influence bending directly, or responses involving ethylene could be more indirect.

Wheeler, Raymond M.↗

Interaction of the carotid baroreflex, the muscle chemoreflex and the cardiopulmonary baroreflex in man during exercise

The interaction of the muscle chemoreflex and the cardiopulmonary baroreflex with the carotid baroreflex in humans performing exercise was investigated in healthy subjects using specially designed exercise regimen and apparatus. Stimulation of the muscle chemoreflex was achieved by restricting blood flow in the exercising muscles by means of applying a pressure of 50 mm Hg, whereas cardiopulmonary baroreceptors were unloaded by employing LBNP of -20 mm Hg. The carotid baroreceptors were unloaded and stimulated by neck-pressure maneuvers (Sprenkle et al., 1986). Results showed that the cardiodecelerating capacity of the carotid baroreflex remains active during exercise, and may even be sensitized by the chemoreflex-induced increase in arterial pressure; but it is not affected by the cardiopulmonary baroreceptor activity.

Eiken, O.↗

NO versus N2O emissions from an NH4(+)-amended Bermuda grass pasture

An enclosure technique is used to monitor soil NO and N2O emissions during early summer regrowth of Bermuda grass (Cynodon dactylon) on sandy loam in a humid, subtropical region of southern Texas. The evolution of both gases was substantially higher from plots harvested at the beginning of the experiment and fertilized five days later with 52 kg N/ha as (NH4)2SO4 than from plots not harvested or fertilized. Emission of NO, but not N2O, was stimulated by clipping and removing the grass, probably because eliminating the shading provided by the dense grass canopy changed these plots from cooler to warmer than unharvested plots, thereby stimulating the activity of soil microorganisms responsible for NO production. Neither gas flux was significantly affected by application of N until the next rainfall dissolved and moved the surface-applied fertilizer into the soil. Immediately thereafter, emissions of NO and N2O increased dramatically to peaks of 160 and 12 g N/ha/d, respectively, and then declined at rates that closely parallel the nitrification rate of added NH4(+), indicating that the gases resulted from the activity of nitrifying microorganisms, rather than denitrifiers. Nitric oxide emissions during the nine-week measurement period averaged 7.2 times greater than N2O emissions and accounted for 3.2 percent of the added N. The data indicate that humid, subtropical grasslands, which not only have large geographical extent but also have been subject to intense anthropogenic disturbance, contribute significantly to the global atmospheric NO(x) budget.

Hutchinson, G. L.↗

The development of system components to provide proprioceptive and tactile information to the human for future telepresence systems

System components are presented that are being implemented to augment teleoperated systems by providing both force and tactile information to the human operator. The concept proposed is the control of a manipulator to perform tasks; i.e., flight line maintenance and repair of combat aircraft or satellites while under the control of a human operator at a remote location to maintain mission effectiveness in a hostile environment. The human would control the motion of the manipulator via a master system with information from the remote site being fed back by direct stimulation of the humans sensory mechanisms or by graphic interpretation of displays. We are interested in providing the operator feedback of position, force, auditory, vision, and tactile information to aide in the human's cognitive ability to control the manipulator. This sensory information from the remote site would then be presented to the operator in such a manner as to enhance his performance while providing him a sense of being present at the remote location, this is known as telepresence. Also discussed is the research done by the Human Sensory Feedback (HSF) facility at the Armstrong Laboratory to provide tactile and proprioceptive feedback to the operator. The system components of this system includes tactile sensor and stimulators, dexterous robotic hands, and the control of positioning and operating industrial robots with exoskeletal mechanisms.

Wright, Ammon K.↗

A proposal to determine properties of the gravitropic response of plants in the absence of a complicating g-force (GTHRES)

Gravitropic responses of oat seedlings (Avena sativa L.) were measured on Earth and in microgravity (IML-1). The seedlings were grown at 1 g either on Earth or on 1 g centrifuges. They were challenged by centripetal accelerations for which the intensity and duration of the stimulations were varied. All stimulation intensities were in the hypogravity region from 0.1 to 1.0 g. All responses occurred either in Spacelab microgravity or during clinorotation on Earth. The experiments were carried out with the same apparatus in Spacelab and on Earth. The experiments addressed a series of scientific questions and useful data were obtained to provide answers to some but not all of those questions.

Brown, Allan H.↗

Melatonin and its precursors in Y79 human retinoblastoma cells - Effect of sodium butyrate

We studied the release of melatonin and the production of its precursors, 5-hydroxytryptophan and serotonin, in cultured Y79 human retinoblastoma cells. This biosynthetic capability was found to be dependent on cell differentiation, which was initiated by culturing Y79 cells for 7 days in dishes coated with poly-D-lysine to promote cell adhesion to the surface of the culture dishes. Differentiation was further induced by exposing the cell monolayer to sodium butyrate (3 mM) for three days. This protocol dramatically increased the release of melatonin, and the syntheses of 5-hydroxytryptophan and serotonin in response to forskolin stimulation. Exposure to dopamine or L-DOPA markedly diminished the forskolin-stimulated release of melatonin, as well as the production of 5-hydroxytryptophan and serotonin. These observations indicate that Y79 cells represent a primitive cell line which, following appropriate differentiation can display biochemical characteristics similar to those of the human retina. Moreover, serotonin synthesis and melatonin release appear to be coupled in Y79 ceils.

Deng, Mei H.↗

Mechanically induced alterations in cultured skeletal muscle growth

Model systems are available for mechanically stimulating cultured skeletal muscle cells by passive tensile forces which simulate those found in vivo. When applied to embryonic muscle cells in vitro these forces induce tissue organogenesis, metabolic adaptations, and muscle cell growth. The mechanical stimulation of muscle cell growth correlates with stretch-induced increases in the efflux of prostaglandins PGE2 and PGF2(alpha) in a time and frequency dependent manner. These prostaglandins act as mechanical 'second messengers' regulating skeletal muscle protein turnover rates. Since they also effect bone remodelling in response to tissue loading and unloading, secreted prostaglandins may serve as paracrine growth factors, coordinating the growth rates of muscle and bone in response to external mechanical forces. Cell culture model systems will supplement other models in understanding mechanical transduction processes at the molecular level.

Vandenburgh, H. H.↗

Efficient vibrational Raman conversion in O2 and N2 cells by use of superfluorescence seeding

We report first-Stokes vibrational conversion efficiency of 21 percent and 35 percent, respectively, in high-pressure O2- and N2-stimulated Raman cells. Broadband superfluorescence is employed to seed these Raman cells, significantly increasing the conversion efficiences with no measured effect on the Raman spectrum. The addition of helium buffer gas reduces competition from stimulated Brillouin scattering and improves the pulse-to-pulse stability and spatial mode quality by increasing the thermal conductivity. Further improvement of the spatial mode quality is achieved by use of gentle heating on the bottom of the cell to induce convection.

Zhang, Barry↗

Melatonin and its precursors in Y79 human retinoblastoma cells: Effect of sodium butyrate

The release of melatonin and the production of its precursors, S-hydroxytryptophan and serotonin, in cultured Y79 human retinoblastoma cells were studied. This biosynthetic capability was found to be dependent on cell differentiation, which was initiated by culturing Y79 cells for 7 days in dishes coated with poly-D-lysine to promote cell adhesion to the surface of the culture dishes. Differentiation was further induced by exposing the cell monolayer to sodium butyrate (3 mM) for 3 days. This protocol dramatically increased the release of melatonin, and the syntheses of 5-hydroxytryptophan and serotonin in response to forskolin stimulation. Exposure to dopamine (10 micro-M) or L-DOPA (100 micro-M) markedly diminished the forskolin-stimulated release of melatonin, as well as the production of 5-hydroxytryptophan and serotonin. These observations indicate that Y79 cells represent a primitive cell line which, following appropriate differentiation (e.g. treatment with sodium butyrate) can display biochemical characteristics similar to those of the human retina. Moreover, serotonin synthesis and melatonin release appear to be coupled in Y79 cells. The inhibition of melatonin release by dopamine supports the hypothesis that in these cells, melatonin and dopamine are components of a retinal feedback loop.

Deng, Mei Hua↗

Feasibility study: Monodisperse polymer particles containing laser-excitable dyes

The optical properties associated with small particles, which include aerosols, hydrosols and solid microspheres have an impact on several areas of science and engineering. Since the advent of high-speed computers and lasers, the interaction of light with matter in the form of small particles with a discontinuous optical boundary relative to the surroundings has been much better understood. Various nonlinear optical effects have been observed involving interaction of a laser beam with both solid microspheres and liquid microdroplets. These include observation of second and third harmonic generation, four wave mixing, optical visibility, two photon absorption, observation of stimulated emission and lasing, and Stimulated Raman Scattering. Many of these effects are observed with laser intensities which are orders of magnitude less than that required by threshold condition for interactions in macroscopic bulk medium. The primary reason for this is twofold. The front surface of the microsphere acts as a thick lens to enhance the internal intensity of the input laser radiation, and the spherical shape of the droplet acts as an optical cavity to provide feedback at specific wavelengths corresponding to the whispering gallery modes or the morphology dependent resonances (MDR's). The most interesting and significant recent finding in this field is undoubtedly the existence of resonance peaks in linear and nonlinear optical spectra. Such resonance peaks are only dependent on the particle morphology, which means the size, shape and refractive index of the particle. Because of the simultaneous presence of these resonances, they have been referred to by many names, including structural resonances, whispering modes or whispering gallery modes, creeping waves, circumferential waves, surfaces modes, and virtual modes. All of these names refer to the same phenomena, i.e. morphology dependent resonances (MDR's) which has already been described and predicted precisely by electromagnetic theory and Loentz-Mie theory since 1908. MDR's can become important when the particle size (radius a) approaches and exceeds the wavelength of the electromagnetic wave (lambda) and the refractive index of the particle is greater than that of the surrounding medium. Such resonances are easiest to observe from a single particle with high symmetry, such as a sphere, spheroid, or cylinder. MDR's correspond to solutions of the characteristic equations of the electromagnetic fields in the presence of a sphere.

Venkateswarlu, Putcha↗

Fluorescence observations of LDEF exposed materials as an indicator of induced material reactions

Observations and measurements of induced changes in the fluorescent emission of materials exposed to the space environment on the Long Duration Exposure Facility (LDEF) have revealed systematic patterns of material-dependent behavior. These results have been supplemented by inspection of similar materials exposed on previous Space Shuttle Missions and in laboratory testing. The space environmental factors affecting the fluorescence of exposed materials have been found to include (but are not necessarily limited to) solar ultraviolet (UV) radiation, atomic oxygen (AO), thermal vacuum exposure, and synergistic combinations of these factors. Observed changes in material fluorescent behavior include stimulation, quenching, and spectral band shifts of emission. For example, the intrinsic yellow fluorescence of zinc oxide pigmented thermal control coatings undergoes quenching as a result of exposure, while coloration is stimulated in the fluorescent emission of several polyurethane coating materials. The changes in fluorescent behavior of these materials are shown to be a revealing indicator of induced material reactions as a result of space environmental exposure.

Linton, Roger C.↗