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At least 1,171 records · Page 65

Absence of arterial baroreflex modulation of skin sympathetic activity and sweat rate during whole-body heating in humans

1. Prior findings suggest that baroreflexes are capable of modulating skin blood flow, but the effects of baroreceptor loading/unloading on sweating are less clear. Therefore, this project tested the hypothesis that pharmacologically induced alterations in arterial blood pressure in heated humans would lead to baroreflex-mediated changes in both skin sympathetic nerve activity (SSNA) and sweat rate. 2. In seven subjects mean arterial blood pressure was lowered (approximately 8 mmHg) and then raised (approximately 13 mmHg) by bolus injections of sodium nitroprusside and phenylephrine, respectively. Moreover, in a separate protocol, arterial blood pressure was reduced via steady-state administration of sodium nitroprusside. In both normothermia and heat-stress conditions the following responses were monitored: sublingual and mean skin temperatures, heart rate, beat-by-beat blood pressure, skin blood flow (laser-Doppler flowmetry), local sweat rate and SSNA (microneurography from peroneal nerve). 3. Whole-body heating increased skin and sublingual temperatures, heart rate, cutaneous blood flow, sweat rate and SSNA, but did not change arterial blood pressure. Heart rate was significantly elevated (from 74 +/- 3 to 92 +/- 4 beats x min(-1); P < 0.001) during bolus sodium nitroprusside-induced reductions in blood pressure, and significantly reduced (from 92 +/- 4 to 68 +/- 4 beats x min(-1); P < 0.001) during bolus phenylephrine-induced elevations in blood pressure, thereby demonstrating normal baroreflex function in these subjects. 4. Neither SSNA nor sweat rate was altered by rapid (bolus infusion) or sustained (steady-state infusion) changes in blood pressure regardless of the thermal condition. 5. These data suggest that SSNA and sweat rate are not modulated by arterial baroreflexes in normothermic or moderately heated individuals.

Clinical Trial↗

Development of a High-Stability Microstrip-based L-band Radiometer for Ocean Salinity Measurements

The development of a microstrip-based L-band Dicke radiometer with the long-term stability required for future ocean salinity measurements to an accuracy of 0.1 psu is presented. This measurement requires the L-band radiometers to have calibration stabilities of less than or equal to 0.05 K over 2 days. This research has focused on determining the optimum radiometer requirements and configuration to achieve this objective. System configuration and component performance have been evaluated with radiometer test beds at both JPL and GSFC. The GSFC testbed uses a cryogenic chamber that allows long-term characterization at radiometric temperatures in the range of 70 - 120 K. The research has addressed several areas including component characterization as a function of temperature and DC bias, system linearity, optimum noise diode injection calibration, and precision temperature control of components. A breadboard radiometer, utilizing microstrip-based technologies, has been built to demonstrate this long-term stability.

Pellerano, Fernando A.↗

ARRISTOTLE Simulation Demo

NASA’s Katherine Johnson Independent Verification and Validation (NASA IV&V) Jon McBride Software Testing and Research (JSTAR) laboratory has developed the Advanced Risk Reduction Integrated Software Test and Operations Tri-program Lightweight Environment (ARRISTOTLE). ARRISTOTLE is a digital twin of NASA’s Artemis mission. ARRISTOLE executes the true SLS and Orion flight binaries integrated on a single laptop computer. This demo will showcase the execution of the full Artemis liftoff. Once airborne, an inflight anomaly will be injected, resulting in Orion detaching from the booster. The Launch Abort System (LAS) will safely bring Orion back to earth. The Unity game engine is used to visualize the flyout as flight software executes.

emulation↗

A Study of Mars Dust Environment Simulation at NASA Johnson Space Center Energy Systems Test Area Resource Conversion Test Facility

The dust environment on Mars is planned to be simulated in a 20 foot thermal-vacuum chamber at the Johnson Space Center, Energy Systems Test Area Resource Conversion Test Facility in Houston, Texas. This vacuum chamber will be used to perform tests and study the interactions between the dust in Martian air and ISPP hardware. This project is to research, theorize, quantify, and document the Mars dust/wind environment needed for the 20 foot simulation chamber. This simulation work is to support the safety, endurance, and cost reduction of the hardware for the future missions. The Martian dust environment conditions is discussed. Two issues of Martian dust, (1) Dust Contamination related hazards, and (2) Dust Charging caused electrical hazards, are of our interest. The different methods of dust particles measurement are given. The design trade off and feasibility were studied. A glass bell jar system is used to evaluate various concepts for the Mars dust/wind environment simulation. It was observed that the external dust source injection is the best method to introduce the dust into the simulation system. The dust concentration of 30 Mg/M3 should be employed for preparing for the worst possible Martian atmosphere condition in the future. Two approaches thermal-panel shroud for the hardware conditioning are discussed. It is suggested the wind tunnel approach be used to study the dust charging characteristics then to be apply to the close-system cyclone approach. For the operation cost reduction purpose, a dehumidified ambient air could be used to replace the expensive CO2 mixture for some tests.

Chen, Yuan-Liang Albert↗

NASA general aviation technology programs

This paper describes the status of the current NASA programs that are aimed at providing new technology for aircraft designs that will improve both safety and utility while reducing the environmental impact of general aviation to acceptable levels. Safety related areas that are discussed include the full scale crash test program and the stall/spin research effort. Among the programs addressing increased utility and performance, advanced airfoil developments and engine cooling drag reduction are discussed. Noise and emission reduction is a subject that is receiving significant emphasis within the NASA programs. Also included is a description of the current status of the hydrogen injection concept as a means of both lowering emissions and increasing fuel economy.

Winblade, R. L.↗

Radial diffusion of Io-injected plasma

The paper reexamines the problem of particle injection by Io and subsequent radial diffusion by flux tube interchange using a proper phase space density formulation. The mathematical formalism is developed, and the theoretical results are compared with the observations, taking into account the pitch angle and energy coverage of the detector on Pioneer 10. Two objectives are pursued: (1) to test the hypothesis of Siscoe and Chen (1977) that Io is the source for all of the plasma observed by Frank et al. (1976) inside 10 R(J); and (2) to describe a simple but flexible method intended to analyze the observations of any other plasma instrument flown through the inner Jovian magnetosphere, e.g., those on Voyager 1 and 2 and Galileo.

Goertz, C. K.↗

Salt-gradient Solar Ponds: Summary of US Department of Energy Sponsored Research

The solar pond research program conducted by the United States Department of Energy was discontinued after 1983. This document summarizes the results of the program, reviews the state of the art, and identifies the remaining outstanding issues. Solar ponds is a generic term but, in the context of this report, the term "solar pond" refers specifically to salt-gradient solar pond. Several small research solar ponds have been built and successfully tested. Procedures for filling the pond, maintaining the gradient, adjusting the zone boundaries, and extracting heat have been developed. Theories and models have also been developed and verified. The major remaining unknowns or issues involve the physical behavior of large ponds; i.e., wind mixing of the surface, lateral range or reach of horizontally injected fluids, ground thermal losses, and gradient zone boundary erosion caused by pumping fluid for heat extraction. These issues cannot be scaled and must be studied in a large outdoor solar pond. This report has been subdivided into three parts. Part One presents the results of the DOE research program. The major contributing institutions include Solar Energy Research Institute, Los Alamos National Laboratory, and Jet Propulsion Laboratory. Part Two presents related independent research conducted by universities. Part Three is a selected bibliography with abstracts.

R.L. French↗

Improved silicon carbide for advanced heat engines

This is the third annual technical report for the program entitled, Improved Silicon Carbide for Advanced Heat Engines, for the period February 16, 1987 to February 15, 1988. The objective of the original program was the development of high strength, high reliability silicon carbide parts with complex shapes suitable for use in advanced heat engines. Injection molding is the forming method selected for the program because it is capable of forming complex parts adaptable for mass production on an economically sound basis. The goals of the revised program are to reach a Weibull characteristic strength of 550 MPa (80 ksi) and a Weibull modulus of 16 for bars tested in 4-point loading. Two tasks are discussed: Task 1 which involves materials and process improvements, and Task 2 which is a MOR bar matrix to improve strength and reliability. Many statistically designed experiments were completed under task 1 which improved the composition of the batches, the mixing of the powders, the sinter and anneal cycles. The best results were obtained by an attritor mixing process which yielded strengths in excess of 550 MPa (80 ksi) and an individual Weibull modulus of 16.8 for a 9-sample group. Strengths measured at 1200 and 1400 C were equal to the room temperature strength. Annealing of machined test bars significantly improved the strength. Molding yields were measured and flaw distributions were observed to follow a Poisson process. The second iteration of the Task 2 matrix experiment is described.

Whalen, Thomas J.↗

Optimization of Orifice Geometry for Cross-Flow Mixing in a Cylindrical Duct

Mixing of gaseous jets in a cross-flow has significant applications in engineering, one example of which is the dilution zone of a gas turbine combustor. Despite years of study, the design of jet injection in combustors is largely based on practical experience. A series of experiments was undertaken to delineate the optimal mixer orifice geometry. A cross-flow to core-flow momentum-flux ratio of 40 and a mass flow ratio of 2.5 were selected as representative of an advanced design. An experimental test matrix was designed around three variables: the number of orifices, the orifice aspect ratio (long-to-short dimension), and the orifice angle. A regression analysis was performed on the data to arrive at an interpolating equation that predicted the mixing performance of orifice geometry combinations within the range of the test matrix parameters. Results indicate that mixture uniformity is a non-linear function of the number of orifices, the orifice aspect ratio, and the orifice angle. Optimum mixing occurs when the asymptotic mean jet trajectories are in the range of 0.35 less than r/R less than 0.5 (where r = 0 is at the mixer wall) at z/R = 1.0. At the optimum number of orifices, the difference between shallow-angled slots with large aspect ratios and round holes is minimal and either approach will lead to good mixing performance. At the optimum number of orifices, it appears possible to have two local optimums where one corresponds to an aspect ratio of 1.0 and the other to a high aspect ratio.

Sowa, W. A.↗

Environmentally Compliant Disposal Method for Heavy Metal Containing Propellants

ABSTRACT An environmentally friendly, cost effective technology has been developed and demonstrated by a team of Naval Air Warfare Center and Lockheed Martin personnel to dispose of Shillelagh solid rocket motor propellants. The Shillelagh is a surface to surface anti-tank weapon approaching the end of its service life. The current demilitarization process employs open detonation, but the presence of lead stearate in the N5 propellant grain motivated the need for the development of an environmentally friendly disposal method. Contained burning of the propellant followed by propellant exhaust processing was chosen as the disposal methodology. The developmental test bed, completed in February 1998, is inexpensive and transportable. Contained burning of Shillelagh propellants posed two technical hurdles: 1) removal of the sub micron lead and cadmium particulate generated during combustion, and 2) secondary combustion of the significant quantifies of carbon monoxide and hydrogen. A firing chamber with a stepped nozzle, air injection, and active ignition was developed to combust the carbon monoxide and hydrogen in real time. The hot gases and particulates from the combustion process are completely contained within a gas holder. The gases are subsequently cooled and routed through a treatment facility to remove the heavy metal particulate. Results indicate that the lead and cadmium particulates are removed below their respective detection limits (2 micro-g/cu m & 0.2 micro-g/cu m) of the analytical procedures employed and that the carbon monoxide and hydrogen levels have been reduced well below the lower flammability limits. Organic concentrations, principally benzene, are I ppm or less. A semi-automated machine has been developed which can rapidly prepare Shillelagh missiles for the contained burn facility. This machine allows the contained burn technology to be more competitive with current open bum open detonation disposal rates.

Decker, M. W.↗

Administration of the non-steroidal anti-inflammatory drug ibuprofen increases macrophage concentrations but reduces necrosis during modified muscle use

OBJECTIVE: To test the hypothesis that ibuprofen administration during modified muscle use reduces muscle necrosis and invasion by select myeloid cell populations. METHODS: Rats were subjected to hindlimb unloading for 10 days, after which they experienced muscle reloading by normal weight-bearing to induce muscle inflammation and necrosis. Some animals received ibuprofen by intraperitoneal injection 8 h prior to the onset of muscle reloading, and then again at 8 and 16 h following the onset of reloading. Other animals received buffer injection at 8 h prior to reloading and then ibuprofen at 8 and 16 h following the onset of reloading. Control animals received buffer only at each time point. Quantitative immunohistochemical analysis was used to assess the presence of necrotic muscle fibers, total inflammatory infiltrate, neutrophils, ED1+ macrophages and ED2+ macrophages at 24 h following the onset of reloading. RESULT: Administration of ibuprofen beginning 8 h prior to reloading caused significant reduction in the concentration of necrotic fibers, but increased the concentration of inflammatory cells in muscle. The increase in inflammatory cells was attributable to a 2.6-fold increase in the concentration of ED2+ macrophages. Animals treated with ibuprofen 8 h following the onset of reloading showed no decrease in muscle necrosis or increase in ED2+ macrophage concentrations. CONCLUSION: Administration of ibuprofen prior to increased muscle loading reduces muscle damage, but increases the concentration of macrophages that express the ED2 antigen. The increase in ED2+ macrophage concentration and decrease in necrosis may be mechanistically related because ED2+ macrophages have been associated with muscle regeneration and repair.

Non-NASA Center↗

Validation and Development of a Fast-Running CFD Model for the No-Vent Fill of Liquid Propellant Tank

Cryogenic fluids, while offering higher energy density than storable propellants, present several handling challenges, including gradual boil-off and tank self-pressurization. Transferring these propellants between tanks can be problematic, as the receiving tank's temperature and pressure often lead to flashing and rapid boil-off upon injection. The No-Vent Fill (NVF) technique mitigates these risks by preventing liquid fuel from being expelled overboard. By controlling tank pressure and ensuring appropriate condensation in the ullage region, the NVF process avoids exceeding vent pressure limits. In this study, Loci/STREAM-VOF simulations were compared with data from NASA K-site test runs on a 2.1 cubic meter tank with a bottom orifice under various no-vent fill conditions, including different wall temperatures, flow rates, and inlet liquid temperatures. The effort demonstrated that Loci/STREAM-VOF is capable of quantitatively capturing the important physics of NVF with submerged jets: (1) validation of the liquid-vapor interface turbulence velocity using previous experimental data showed good agreement at different fill levels; (2) validation of the CFD Stanton number for mass transfer provided an adequate mass transfer coefficient range; (3) consistent pressure agreements were found in the pressure history for both cold and warm conditions; and (4) the variations of final pressure with flow rate and inlet liquid temperature were well predicted by the CFD simulation. The application of NVF for low-gravity conditions will be studied in future work.

CFD↗

Validation and Development of a Fast-Running CFD Model for the No-Vent Fill of Liquid Propellant Tank

Cryogenic fluids, while offering higher energy density than storable propellants, present several handling challenges, including gradual boil-off and tank self-pressurization. Transferring these propellants between tanks can be problematic, as the receiving tank's temperature and pressure often lead to flashing and rapid boil-off upon injection. The No-Vent Fill (NVF) technique mitigates these risks by preventing liquid fuel from being expelled overboard. By controlling tank pressure and ensuring appropriate condensation in the ullage region, the NVF process avoids exceeding vent pressure limits. In this study, Loci/STREAM-VOF simulations were compared with data from NASA K-site test runs on a 2.1 cubic meter tank with a bottom orifice under various no-vent fill conditions, including different wall temperatures, flow rates, and inlet liquid temperatures. The effort demonstrated that Loci/STREAM-VOF is capable of quantitatively capturing the important physics of NVF with submerged jets: (1) validation of the liquid-vapor interface turbulence velocity using previous experimental data showed good agreement at different fill levels; (2) validation of the CFD Stanton number for mass transfer provided an adequate mass transfer coefficient range; (3) consistent pressure agreements were found in the pressure history for both cold and warm conditions; and (4) the variations of final pressure with flow rate and inlet liquid temperature were well predicted by the CFD simulation. The application of NVF for low-gravity conditions will be studied in future work.

CFD↗

Thermal Protection Systems Technology Transfer from Apollo and Space Shuttle to the Orion Program

This paper describes how the Orion program is utilizing the Thermal Protection System (TPS) experience from the Apollo and Space Shuttle programs to reduce program risk and improve affordability to meet NASA's future manned exploration missions. The Orion program successfully completed the Exploration Flight Test (EFT-1) mission in 2014 and is currently assembling, integrating, and testing the next spacecraft for the Exploration Mission (EM-1) to meet the flight test objectives of an unmanned orbital mission to the moon and return to earth in 2019. The Orion spacecraft production operations are located in the Neil Armstrong Operations and Checkout (O&C) facility at the Kennedy Space Center (KSC) providing an affordable and seamless delivery approach of vehicles directly to the launch site eliminating spacecraft transportation and additional checkout testing. Innovative vehicle design, manufacturing and test operations approaches are maturing and evolving with each Orion vehicle build to support the challenging NASA exploration mission requirements beyond Low Earth Orbit (LEO) while reducing program cost and schedule impacts. An example of Orion's evolution is the incorporation of an improved heat shield design, assembly and testing approach to meet the higher re-entry velocities for a lunar return for the EM-1 mission. The EFT- 1 heat shield was based on the Apollo heat shield manufacturing processes and was assembled at a supplier location and then transported to KSC for final integration. The EM-1 heat shield is now manufactured, assembled, tested, and installed into the spacecraft at the O&C facility reducing program cost and production schedules. The transition of the Space Shuttle TPS capabilities has enabled Orion to provide a human rated capsule design using proven materials and processes established over years of orbiter re-entry missions. The Orion Crew Module (CM) TPS configuration is derived from the Apollo CM approach utilizing improved materials and processes developed from the Space Shuttle program. The Orion EFT-1 heat shield utilized the Avcoat ablative material from Apollo which was injected into a honeycomb substrate and has been updated for EM-1 incorporating a block configuration bonded to a composite shell structure. This approach utilizes the proven Avcoat material for the heat shield ablator and is utilizing derived bonding and inspection methods and techniques from the Space Shuttle tile experience. The Orion back shell TPS configuration is based on Space Shuttle tile designs using proven tile materials and coatings. The Orion forward bay cover utilizes the high temperature tiles similar to the back shell tiles and low temperature blankets derived from the Space Shuttle program reducing weight impacts. Space Shuttle Multi-Layer Insulation (MLI) is installed in the Orion capsule to control the interior temperature environment providing a light weight design. These TPS design approaches have performed successfully on the Orion first flight test on EFT-1 and are incorporated in the configuration for the next flight test for EM-1. Completion of these two flight tests will certify the TPS for the Orion program for human rated exploration missions and has reduced the development cost to the Orion program. In addition to transitioning the Space Shuttle TPS design configurations to Orion, the supporting manufacturing infrastructure, manufacturing processes, and inspection methods are also incorporated into the Orion assembly operations at KSC. This has avoided significant startup schedule and costs impacts of new capabilities and development of support operations necessary to fabricate, install, inspect, and validate the TPS installations for the Orion spacecraft. The Thermal Protection System Facility (TPSF) which supported the Space Shuttle program provides the heat shield Avcoat blocks and the back shell AETB-8 tiles for Orion program. Extending the existing Space Shuttle TPS operations at KSC provides onsite support to the Orion spacecraft assembly operations. A significant benefit to the Orion program is the transition of the Space Shuttle technician work force at KSC. This highly skilled workforce was able to transition to the Orion program and immediately support the TPS installation operations. They brought with them the human rated manufacturing and assembly operations culture that was critical to the Space Shuttle success avoiding the retraining cost and schedule impacts of a new workforce to Orion. The technician skills certification program from the Space Shuttle was found to be compatible with the Lockheed Martin technician certification programs enabling a seamless training process utilizing process similarity avoiding the cost of retraining the work force to Orion standards. The existing workforce is certificated for multiple processes enabling reassignment of technicians to other tasks in the Orion AI&P operations reducing the overall touch labor manpower requirements. Additional benefits of using the Space Shuttle workforce is the incorporation of the lessons learned from Space Shuttle processes to improve the Orion TPS processes. This has resulted in a continuous evolution of TPS processes to improve the producibility and reduce the program cost for the TPS for the Orion program. Transitioning the Apollo and Space Shuttle TPS designs, processes, and technician workforce has been instrumental in enabling Orion to successfully meet the program challenges for NASA's exploration missions of the future.

Stewart, Michael↗

Operation of small rocket engines in the JPL high-vacuum molecular space simulator (Molsink)

The feasibility of operating small rocket engines in the Molsink facility was demonstrated. A 0.44-N (0.1-lbf) hydrazine engine and a 0.18-N (0.04-lbf) thruster using cold gas from a hydrazine plenum system were operated for both flight duty cycles and off-nominal conditions. The exhaust gases from these thrusters contain NH3, N2, and H2. The chamber was also calibrated for larger bipropellant engines using nitrogen tetroxide/monomethyl hydrazine (NTO/MMH). The exhaust products of these engines contain CO2, CO, H2, H2O, and H2. A mixture of cold gases simulating the engine exhaust was injected through a nozzle under conditions simulating thrust levels up to 26.7-N (6 lbf). Pulsing and continuous operations were investigated. The chamber background pressure traces were compared with the traces obtained for the same thrusters operated with pure nitrogen at approximately equivalent thrust. Satisfactory recuperation times were encountered in all the pulsing modes. Test times greater than 20s were obtained in steady state operation before the vacuum chamber back pressure climbed to prohibitive values.

Chirivella, J. E.↗

Performance and combustion characteristics of direct-injection stratified-charge rotary engines

Computer simulations of the direct-injection stratified-charge (DISC) Wankel engine have been used to calculate heat release rates and performance and efficiency characteristics of the 1007R engine. Engine pressure data have been used in a heat release analysis to study the effects of heat transfer, leakage, and crevice flows. Predicted engine performance data are compared with experimental test data over a range of engine speeds and loads. An examination of methods to improve the performance of the Wankel engine with faster combustion, reduced leakage, higher compression ratio, and turbocharging is presented.

Nguyen, Hung Lee↗

Scramjet combustor and nozzle computations

The SHIP3D PNS code is used to conduct a 3D parametric study of a scramjet combustor and nozzle configuration at flight Mach numbers of 8, 10, 12, 16, and 20. The study demonstrated the powerful computational strategy of using a highly efficient, modified PNS code and a nonkinetic chemistry model to analyze test data and conduct parametric studies of scramjet combustors and nozzles. The mixing efficiency was found to decrease by 0.2 when the flight Mach number increased from 8 to 12 and showed little change at higher Mach numbers. The protruding ramp injector generated an oblique shock that impinged on the cowl. Ramp-slot injection produced better mixing, both because of the interaction of this shock with the slot fuel, and because of better fuel distribution in the duct. The former effect was enhanced when the ramp angle was increased. Mixing was also enhanced when the ramp fuel injection angle and sweep angle were increased.

Kamath, Pradeep S.↗

Dual-Pump CARS Thermometry and Species Concentration Measurements in a Supersonic Combustor

The dual-pump coherent anti-Stokes Raman spectroscopy (CARS) method was used to measure temperature and the absolute mole fractions of N2, O2 and H2 in a supersonic combustor. Experiments were conducted in NASA Langley Research Center's Direct Connect Supersonic Combustion Test Facility. In this facility, hydrogen and air bum to increase the enthalpy of the test gas; O2 is then added to simulate air. This gas is expanded through a Mach 2 nozzle and into a combustor model consisting of a short constant-area section followed by a small rearward facing step and another constant area section. At the end of this straight section H2 fuel is then injected at Mach 2 and at 30 deg. angle with respect to the freestream. One wall of the duct then expands at a 3 deg. angle for over 1 meter. The ensuing combustion is monitored optically through ports in the side of the combustor. CARS measurements were performed at the nozzle exit and at four different planes downstream fuel injection. Maps were obtained of the mean temperature, as well as quantitative N2 and O2 and qualitative H2 mean mole fraction fields. Correlations between fluctuations of the different measured parameters are presented for one of the planes of data.

OByrne, Sean↗