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At least 1,171 records · Page 65

Applied Nanotechnology for Human Space Exploration

A viewgraph presentation describing nanotechnology for human space exploration is shown. The topics include: 1) NASA's Strategic Vision; 2) Exploration Architecture; 3) Future Exploration Mission Requirements Cannot be met with Conventional Materials; 4) Nanomaterials: Single Wall Carbon Nanotubes; 5) Applied Nanotechnology at JSC: Fundamentals to Applications; 6) Technology Readiness Levels (TRL); 7) Growth, Modeling, Diagnostics and Production; 8) Characterization: Purity, Dispersion and Consistency; 9) Processing; 10) Nanoelectronics: Enabling Technologies; 11) Applications for Human Space Exploration; 12) Exploration Life Support: Atmosphere Revitalization System; 13) Advanced and Exploration Life Support: Regenerable CO2 Removal; 14) Exploration Life Support: Water Recovery; 15) Advanced Life Support: Water Disinfection/Recovery; 16) Power and Energy: Supercapacitors and Fuel Cells; 17) Nanomaterials for EMI Shielding; 18) Active Radiation Dosimeter; 19) Advanced Thermal Protection System (TPS) Repair; 20) Thermal Radiation and Impact Protection (TRIPS); 21) Nanotechnology: Astronaut Health Management; 22) JSC Nanomaterials Group Collaborations.

Yowell, Leonard L.↗

Cold Helium Pressurization for Liquid Oxygen/Liquid Methane Propulsion Systems: Fully-Integrated Hot-Fire Test Results

Hot-fire test demonstrations were successfully conducted using a cold helium pressurization system fully integrated into a liquid oxygen (LOX) / liquid methane (LCH4) propulsion system (Figure 1). Cold helium pressurant storage at near liquid nitrogen (LN2) temperatures (-275 F and colder) and used as a heated tank pressurant provides a substantial density advantage compared to ambient temperature storage. The increased storage density reduces helium pressurant tank size and mass, creating payload increases of ~35% for small lunar-lander sized applications. This degree of mass reduction also enables pressure-fed propulsion systems for human-rated Mars ascent vehicle designs. Hot-fire test results from the highly-instrumented test bed will be used to demonstrate system performance and validate integrated models of the helium and propulsion systems. A pressurization performance metric will also be developed as a means to compare different active pressurization schemes.

Morehead, R. L.↗

Chimeric Mouse Models for Space Radiation Risk Investigations

Assessment of human health risks associated with space radiation exposure is based largely on the knowledge learned from studies in which animals, mostly rodents, are exposed to high-LET radiation on the ground. It has been recognized that translation of animal results to meaningful implications for human disease can be challenging, particularly for certain risk categories such as the high-LET radiation effects in the central nervous system (CNS). Considering limitations in utilizing non-human primates and clinical studies in humans, chimeric animals can potentially bridge the knowledge gap between rodents and humans. In a chimeric animal, a specific organ or a cell type is replaced with respective human cells that are functional. A number of chimeric mouse models have been developed in the medical research community to study human diseases, and some of the models can potentially be used for NASA applications. Here we investigate use of mice engrafted with human hepatocytes, which have been used in studies of genotoxicity from carcinogen exposures, for assessment of space radiation damage. In a pilot study, we use PXB mice whose livers contain >90% human cells and have been found to function nearly identically to human liver tissues. These mice were exposed to gamma rays for investigations of DNA damage, transcriptomics, and histopathological changes in the humanized livers. Results obtained from PXB mice were compared non-engrafted control animals from the same background strain that are exposed to identical conditions. Preliminary data from histopathological analysis suggest chimeric mouse models are suitable for investigations of space radiation risks, as the humanized liver tissue exhibited changes induced by radiation and was markedly distinct from the liver tissue from the control animals (Fox Chase SCID mice).

Radiation effects↗

Chimeric Mouse Models for Space Radiation Risk Investigations

Assessment of human health risks associated with space radiation exposure is based largely on the knowledge learned from studies in which animals, mostly rodents, are exposed to high-LET radiation on the ground. It has been recognized that translation of animal results to meaningful implications for human disease can be challenging, particularly for certain risk categories such as the high-LET radiation effects in the central nervous system (CNS). Considering limitations in utilizing non-human primates and clinical studies in humans, chimeric animals can potentially bridge the knowledge gap between rodents and humans. In a chimeric animal, a specific organ or a cell type is replaced with respective human cells that are functional. A number of chimeric mouse models have been developed in the medical research community to study human diseases, and some of the models can potentially be used for NASA applications. Here we investigate use of mice engrafted with human hepatocytes, which have been used in studies of genotoxicity from carcinogen exposures, for assessment of space radiation damage. In a pilot study, we use PXB mice whose livers contain >90% human cells and have been found to function nearly identically to human liver tissues. These mice were exposed to gamma rays for investigations of DNA damage, transcriptomics, and histopathological changes in the humanized livers. Results obtained from PXB mice were compared non-engrafted control animals from the same background strain that are exposed to identical conditions. Preliminary data from histopathological analysis suggest chimeric mouse models are suitable for investigations of space radiation risks, as the humanized liver tissue exhibited changes induced by radiation and was markedly distinct from the liver tissue from the control animals (Fox Chase SCID mice).

Radiation effects↗

A taxonomy for the evolution of human settlements on the moon and Mars

A proposed structure is described for partnerships with shared interests and investments to develop the technology and approach for evolutionary surface systems for the moon and Mars. Five models are presented for cooperation with specific references to the technical evolutionary path of the surface systems. The models encompass the standard customer/provider relationship, a concept for exclusive government use, a joint venture with a government-sponsored non-SEI market, a technology joint-development approach, and a redundancy model to insure competitive pricing. The models emphasize the nonaerospace components of the settlement technologies and the decentralized nature of surface systems that make the project suitable for private industrial development by several companies. It is concluded that the taxonomy be considered when examining collaborative opportunities for lunar and Martian settlement.

Roberts, Barney B.↗

Cryogenic Fluid Management Using CFD - Development and Applications

The Fluid Dynamics Branch has positioned itself to support a wide range of customers in need of Cryogenic Fluid Management (CFM) analysis. A computational fluid dynamics (CFD) tool used for all manner of internal and external propulsion applications has been extended and refined to better model cryogenic propellant storage and tanking operations. Through the CFM Portfolio project, several validation activities were initiated. Validation of propellant tank self-pressurization, autogenous pressurization, slosh-induced ullage collapse, and jet-induced mixing all aid in defining model accuracy. The on-going validation effort has enabled confident application of the tool to in-line design and evaluation of CFM hardware and operations. Recent project support included design of no-vent fill operations using various techniques for the Human Landing System (HLS). Propellant transfer dynamics were predicted to ensure complete propellant delivery. Many more activities in support of HLS and other projects and programs were supported. The branch has engaged the CFM community to share recent findings and capabilities through conferences. To reach the wider community, a consolidation of fundamental findings from work on in-space pulsed settling maneuvers was distilled in an AIAA paper. Development and demonstration of CFM modeling capabilities continues in order to meet the needs of the agency and its industry partners in the endeavor to sustainably reach the Moon and beyond.

Jacob Brodnick↗

NASA's Carbon Cycle OSSE Initiative - Informing Future Space-Based Observing Strategies Through Advanced Modeling and Data Assimilation

Land and ocean carbon sinks absorb half of human CO2 emissions. The fate of these sinks in a changing world is unknown, introducing large uncertainties in climate projections. Satellite measurements of atmospheric CO2 are required to better understand the processes governing carbon uptake. Careful planning of future missions using Observing System Simulation Experiments (OSSEs) can help ensure that they meet the needs of the scientific and policy communities. NASA's Carbon Cycle OSSE Initiative brings together researchers from multiple universities and NASA centers to create model-derived data products in support of informed mission planning.

Ott, Lesley↗

Planned Investigations to Address Acute Central Nervous System Effects of Space Radiation Exposure with Human Performance Data

This work intends to generate evidence of acute, incremental human performance decrement similar to that due to space radiation andits impacts on the brain, to accompany ongoing human performance modeling work. The planned work will explore the boundaries of human behavioral and performance decrement after exposure to stress, which may be expected based in part on rodent responses found afterexposure to ionizing radiation. The collection of evidence via simulation studies can characterize real human errors toward determining what stress levels lead to significantly-low levels of performance (below permissible outcome limits) which would imperilmission accomplishment. If mission-relevant animal-study-linked tasks are used, human and animal performance levels may be aligned to enable quantitative assignment of permissible exposure limits based on animal exposure studies. Ultimately, a transfer function between the performances of exposed rodents and humans under stress can be developed using shared impairment mechanisms.

human performance↗

Common Habitat for Long Duration Transit and Surface Operations

This concept is based on the Skylab II concept, which proposes using a SLS propellant tank as the primary structure of a habitat. Common Habitat takes this a step further, proposing an interior architecture that is equally viable as a lunar surface hab, transit hab, and Mars surface hab, thus enabling a single development to support all three long duration habitat roles. Common Habitat has been pursued by the PI and co-investigators at MSFC and other centers in a spare time / funding available basis, often with heavy student intern support. Student resources have developed preliminary concepts, but these models must be refined to reflect accurate vehicle subsystems, utilities, stowage, workstations, and other crew systems. This investigation applies NASA civil servant and contractor expertise to correct errors in the most recent student concepts in order to prepare them for future human-in-the-loop evaluations to determine the most viable configuration for a Common Habitat. In prior studies there was never an opportunity to trade both crew size and internal orientation. Prior work has been a series of point designs with inconsistent design constraints, making apples to apples comparisons impossible. The most recent student work produced CAD models of four habitat variants for future use in a trade study, but the student products contain model construction and geometry errors, inaccurate subsystems design and placement, and unrealistic structural elements and outfitting. These must be corrected before the models can be moved into a VR environment for humanin- the-loop testing. Through consultation with SMEs throughout the Agency, the fidelity of these designs will be upgraded to a level of quality sufficient to make a comparative analysis of crew size sensitivity and internal orientation. The product of this activity is four upgraded CAD models, each reflecting a different configuration of the Common Habitat. One is a horizontal configuration using the full length of the SLS LOX tank. One is a vertical configuration using the same tank dimensions. The third is a horizontal configuration using a truncated SLS LOX tank (half the barrel length). The fourth is a vertical configuration of the half-length SLS LOX tank.

Howard, Robert L.↗

Application of the epidemiological model in studying human error in aviation

An epidemiological model is described in conjunction with the analytical process through which aviation occurrence reports are composed into the events and factors pertinent to it. The model represents a process in which disease, emanating from environmental conditions, manifests itself in symptoms that may lead to fatal illness, recoverable illness, or no illness depending on individual circumstances of patient vulnerability, preventive actions, and intervention. In the aviation system the analogy of the disease process is the predilection for error of human participants. This arises from factors in the operating or physical environment and results in errors of commission or omission that, again depending on the individual circumstances, may lead to accidents, system perturbations, or harmless corrections. A discussion of the previous investigations, each of which manifests the application of the epidemiological method, exemplifies its use and effectiveness.

Cheaney, E. S.↗

Steady-state evoked potentials possibilities for mental-state estimation

The use of the human steady-state evoked potential (SSEP) as a possible measure of mental-state estimation is explored. A method for evoking a visual response to a sum-of-ten sine waves is presented. This approach provides simultaneous multiple frequency measurements of the human EEG to the evoking stimulus in terms of describing functions (gain and phase) and remnant spectra. Ways in which these quantities vary with the addition of performance tasks (manual tracking, grammatical reasoning, and decision making) are presented. Models of the describing function measures can be formulated using systems engineering technology. Relationships between model parameters and performance scores during manual tracking are discussed. Problems of unresponsiveness and lack of repeatability of subject responses are addressed in terms of a need for loop closure of the SSEP. A technique to achieve loop closure using a lock-in amplifier approach is presented. Results of a study designed to test the effectiveness of using feedback to consciously connect humans to their evoked response are presented. Findings indicate that conscious control of EEG is possible. Implications of these results in terms of secondary tasks for mental-state estimation and brain actuated control are addressed.

Junker, Andrew M.↗

Exploration Life Support Critical Questions for Future Human Space Missions

Exploration Life Support (ELS) is a current project under NASA's Exploration Systems Mission Directorate. The ELS Project plans, coordinates and implements the development of advanced life support technologies for human exploration missions in space. Recent work has focused on closed loop atmosphere and water systems for long duration missions, including habitats and pressurized rovers. But, what are the critical questions facing life support system developers for these and other future human missions? This paper explores those questions and how progress in the development of ELS technologies can help answer them. The ELS Project includes the following Elements: Atmosphere Revitalization Systems, Water Recovery Systems, Waste Management Systems, Habitation Engineering, Systems Integration, Modeling and Analysis, and Validation and Testing, which includes the Sub-Elements Flight Experiments and Integrated Testing. Systems engineering analysis by ELS seeks to optimize overall mission architectures by considering all the internal and external interfaces of the life support system and the potential for reduction or reuse of commodities. In particular, various sources and sinks of water and oxygen are considered along with the implications on loop closure and the resulting launch mass requirements. Systems analysis will be validated through the data gathered from integrated testing, which will demonstrate the interfaces of a closed loop life support system. By applying a systematic process for defining, sorting and answering critical life support questions, the ELS project is preparing for a variety of future human space missions

Kwert, Michael K.↗

Biological Visualization, Imaging and Simulation(Bio-VIS) at NASA Ames Research Center: Developing New Software and Technology for Astronaut Training and Biology Research in Space

The Bio- Visualization, Imaging and Simulation (BioVIS) Technology Center at NASA's Ames Research Center is dedicated to developing and applying advanced visualization, computation and simulation technologies to support NASA Space Life Sciences research and the objectives of the Fundamental Biology Program. Research ranges from high resolution 3D cell imaging and structure analysis, virtual environment simulation of fine sensory-motor tasks, computational neuroscience and biophysics to biomedical/clinical applications. Computer simulation research focuses on the development of advanced computational tools for astronaut training and education. Virtual Reality (VR) and Virtual Environment (VE) simulation systems have become important training tools in many fields from flight simulation to, more recently, surgical simulation. The type and quality of training provided by these computer-based tools ranges widely, but the value of real-time VE computer simulation as a method of preparing individuals for real-world tasks is well established. Astronauts routinely use VE systems for various training tasks, including Space Shuttle landings, robot arm manipulations and extravehicular activities (space walks). Currently, there are no VE systems to train astronauts for basic and applied research experiments which are an important part of many missions. The Virtual Glovebox (VGX) is a prototype VE system for real-time physically-based simulation of the Life Sciences Glovebox where astronauts will perform many complex tasks supporting research experiments aboard the International Space Station. The VGX consists of a physical display system utilizing duel LCD projectors and circular polarization to produce a desktop-sized 3D virtual workspace. Physically-based modeling tools (Arachi Inc.) provide real-time collision detection, rigid body dynamics, physical properties and force-based controls for objects. The human-computer interface consists of two magnetic tracking devices (Ascention Inc.) attached to instrumented gloves (Immersion Inc.) which co-locate the user's hands with hand/forearm representations in the virtual workspace. Force-feedback is possible in a work volume defined by a Phantom Desktop device (SensAble inc.). Graphics are written in OpenGL. The system runs on a 2.2 GHz Pentium 4 PC. The prototype VGX provides astronauts and support personnel with a real-time physically-based VE system to simulate basic research tasks both on Earth and in the microgravity of Space. The immersive virtual environment of the VGX also makes it a useful tool for virtual engineering applications including CAD development, procedure design and simulation of human-system systems in a desktop-sized work volume.

Smith, Jeffrey↗

Satellite Contributions to Global Change Studies

By providing a global view with a level playing field (no region missed because of unfavorable surface conditions or political boundaries), satellites have made major contributions to improved monitoring and understanding of our constantly changing planet. The global view has allowed surprising realizations like the relative sparsity of lightning strikes over oceans and the large-scale undulations on the massive Antarctic ice sheet. It has allowed the tracking of all sorts of phenomena, including aerosols, both natural and anthropogenic, as they move with the atmospheric circulation and impact weather and human health. But probably nothing that the global view allows is more important in the long term than its provision. of unbiased data sets to address the issue of global change, considered by many to be among the most important issues facing humankind today. With satellites we can monitor atmospheric temperatures at all latitudes and longitudes, and obtain a global average that lessens the likelihood of becoming endlessly mired in the confusions brought about by the certainty of regional differences. With satellites we can monitor greenhouse gases such as CO2 not just above individual research stations but around the globe. With satellites we can monitor the polar sea ice covers, as we have done since the late 1970s, determining and quantifying the significant reduction in Arctic sea ice and the slight growth in Antarctic sea ice over that period, With satellites we can map the full extent and changes in the Antarctic stratospheric ozone depletions that were first identified from using a single ground station; and through satellite data we have witnessed from afar land surface changes brought about by humans both intentionally, as with wide-scale deforestation, and unintentionally, as with the decay of the Aral Sea. The satellite data are far from sufficient for all that we need in order to understand the global system and forecast its changes, as we also need sophisticated climate models, in situ process studies, and data sets that extend back well before the introduction of satellite technology. Nonetheless, the repetitive, global view provided by satellites is contributing in a major way to our improved recognition of how the Earth im changing, a recognition that is none too soon in view of the magnitude of the impacts that humans can now have.

Parkinson, Claire L.↗

Applied Meteorology Unit (AMU) Quarterly Report

By providing a global view with a level playing field (no region missed because of unfavorable surface conditions or political boundaries), satellites have made major contributions to improved monitoring and understanding of our constantly changing planet. The global view has allowed surprising realizations like the relative sparsity of lightning strikes over oceans and the large-scale undulations on the massive Antarctic ice sheet. It has allowed the tracking of all sorts of phenomena, including aerosols, both natural and anthropogenic,as they move with the atmospheric circulation and impact weather and human health. But probably nothing that the global view allows is more important in the long term than its provision of unbiased data sets to address the issue of global change, considered by many to be among the most important issues facing humankind today. With satellites we can monitor atmospheric temperatures at all latitudes and longitudes, and obtain a global average that lessens the likelihood of becoming endlessly mired in the confusions brought about by the certainty of regional differences. With satellites we can monitor greenhouse gases such as CO2 not just above individual research stations but around the globe. With satellites we can monitor the polar sea ice covers, as we have done since the late 1970s, determining and quantifying the significant reduction in Arctic sea ice and the slight growth in Antarctic sea ice over that period. With satellites we can map the full extent and changes in the Antarctic stratospheric ozone depletions that were first identified from a single ground station; and through satellite data we have witnessed from afar land surface changes brought about by humans both intentionally, as with wide-scale deforestation, and unintentionally, as with the decay of the Aral Sea. The satellite data are far from sufficient for all that we need in order to understand the global system and forecast its changes, as we also need sophisticated climate models, in situ process studies, and data sets that extend back well before the introduction of satellite technology. Nuomthc)cmm, the repetitive, global view provided by satellites is contributing in a major way to our improved recognition of how the Earth is changing, a recognition that is none too soon in view of the magnitude of the impacts that humans can now have.

Bauman, William↗

Temporal sensitivity

Human visual temporal sensitivity is examined. The stimuli used to measure temporal sensitivity are described and the linear systems theory is reviewed in terms of temporal sensitivity. A working model which represents temporal sensitivity is proposed. The visibility of a number of temporal wave forms, sinusoids, rectangular pulses, and pulse pairs, is analyzed. The relation between spatial and temporal effects is studied. Temporal variations induced by image motion and the effects of light adaptation on temporal sensitivity are considered.

Watson, Andrew B.↗

Analysis of the Variable Pressure Growth Chamber using the CASE/A simulation package

A computer simulation of the Variable Pressure Growth Chamber (VPGC), located at the NASA Johnson Space Center, has been developed using the Computer Aided Systems Engineering and Analysis (CASE/A) package. The model has been used to perform several analyses of the VPGC. The analyses consisted of a study of the effects of a human metabolic load on the VPGC and a study of two new configurations for the temperature and humidity control (THC) subsystem in the VPGC. The objective of the human load analysis was to study the effects of a human metabolic load on the air revitalization and THC subsystems. This included the effects on the quantity of carbon dioxide injected and oxygen removed from the chamber and the effects of the additional sensible and latent heat loads. The objective of the configuration analysis was to compare the two new THC configurations against the current THC configuration to determine which had the best performance.

Mcfadden, Carl D.↗

Perceptual organization in computer vision - A review and a proposal for a classificatory structure

The evolution of perceptual organization in biological vision, and its necessity in advanced computer vision systems, arises from the characteristic that perception, the extraction of meaning from sensory input, is an intelligent process. This is particularly so for high order organisms and, analogically, for more sophisticated computational models. The role of perceptual organization in computer vision systems is explored. This is done from four vantage points. First, a brief history of perceptual organization research in both humans and computer vision is offered. Next, a classificatory structure in which to cast perceptual organization research to clarify both the nomenclature and the relationships among the many contributions is proposed. Thirdly, the perceptual organization work in computer vision in the context of this classificatory structure is reviewed. Finally, the array of computational techniques applied to perceptual organization problems in computer vision is surveyed.

Sarkar, Sudeep↗