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At least 1,171 records · Page 65

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NASA NTRS2019

Design, Prototyping, and Testing of a Novel Flowpath with an Array of Six 3D Matrix Vitvo Bioreactors for the NASA Bioculture System

The NASA Bioculture System is an advanced cell culture closed-loop system containing highly automated flowpaths designed to conduct long term biology experiments on ISS with earth remote controllable medium flow, temperature, gas composition, medium exchange, cell sampling and fixation. This technology was already demonstrated with successful cardiomyocyte and osteocyte cultures experiments onboard the ISS and is now supporting NASA PI science. The Bioculture System, however, can only support 10 cassettes with disposable flowpaths, each containing a single hollow fiber bioreactor with a culture capacity of about 2ml. This constraint not only severely limits the number of investigators that can conduct experiments in space, but also subjects the experiments to limitations in the number of replicates and conditions that can be studied. To address these limitations, we sought a novel design solution to maximize the number of separate bioreactor cultures and volume that can be conducted simultaneously. To this end we designed, prototyped, and are now testing a six-Vitvo 3D Matrix 2ml bioreactor insert that replaces the conventional Bioculture System hollow fiber bioreactor. This design will allow the Bioculture System to support up to 60 different bioreactors and samples at once. Specifically, the novel gas-tight containment housing insert contains six COTS Rigenerand VITVO bioreactors stacked on each side of a heat sink powered by the existing heating element and pair of temperature sensors. Medium will be distributed into each bioreactor's cell-free chamber via its built-in Luer connector, then across the 3D matrix to the cell chamber, dissipating laminar flow and limiting fluid shear stresses that might mechanostimulate cell cultures. Gas (5% CO2 in air) will be supplied directly to the bioreactor gas-tight housing for exchange via the bioreactor flat-surface gas-permeable membranes, eliminating the need for the existing Bioculture System cassette oxygenator. If successfully implemented on ISS, this new multi-bioreactor insert for the Bioculture System has the potential to make real-time cell science experimentation in space more efficient and accessible to more investigators.

Ma, Kristin R.↗

NASA NTRS1977

Data processing for the DMSP microwave radiometer system

A software program was developed and tested to process microwave radiometry data to be acquired by the microwave sensor (SSM/T) on the Defense Meteorological Satellite Program spacecraft. The SSM/T 7-channel microwave radiometer and systems data will be data-linked to Air Force Global Weather Central (AFGWC) where they will be merged with ephemeris data prior to product processing for use in the AFGWC upper air data base (UADB). The overall system utilizes an integrated design to provide atmospheric temperature soundings for global applications. The fully automated processing at AFGWC was accomplished by four related computer processor programs to produce compatible UADB soundings, evaluate system performance, and update the a priori developed inversion matrices. Tests with simulated data produced results significantly better than climatology.

Rigone, J. L.↗

NASA NTRS2015

Imaging Flash Lidar for Safe Landing on Solar System Bodies and Spacecraft Rendezvous and Docking

NASA has been pursuing flash lidar technology for autonomous, safe landing on solar system bodies and for automated rendezvous and docking. During the final stages of the landing from about 1 kilometer to 500 meters above the ground, the flash lidar can generate 3-Dimensional images of the terrain to identify hazardous features such as craters, rocks, and steep slopes. The onboard flight computer can then use the 3-D map of terrain to guide the vehicle to a safe location. As an automated rendezvous and docking sensor, the flash lidar can provide relative range, velocity, and bearing from an approaching spacecraft to another spacecraft or a space station. NASA Langley Research Center has developed and demonstrated a flash lidar sensor system capable of generating 16,000 pixels range images with 7 centimeters precision, at 20 Hertz frame rate, from a maximum slant range of 1800 m from the target area. This paper describes the lidar instrument and presents the results of recent flight tests onboard a rocket-propelled free-flyer vehicle (Morpheus) built by NASA Johnson Space Center. The flights were conducted at a simulated lunar terrain site, consisting of realistic hazard features and designated landing areas, built at NASA Kennedy Space Center specifically for this demonstration test. This paper also provides an overview of the plan for continued advancement of the flash lidar technology aimed at enhancing its performance to meet both landing and automated rendezvous and docking applications.

Amzajerdian, Farzin↗

NASA NTRS1974

Automated microbial metabolism laboratory

The design and rationale of an advanced labeled release experiment based on single addition of soil and multiple sequential additions of media into each of four test chambers are outlined. The feasibility for multiple addition tests was established and various details of the methodology were studied. The four chamber battery of tests include: (1) determination of the effect of various atmospheric gases and selection of that gas which produces an optimum response; (2) determination of the effect of incubation temperature and selection of the optimum temperature for performing Martian biochemical tests; (3) sterile soil is dosed with a battery of C-14 labeled substrates and subjected to experimental temperature range; and (4) determination of the possible inhibitory effects of water on Martian organisms is performed initially by dosing with 0.01 ml and 0.5 ml of medium, respectively. A series of specifically labeled substrates are then added to obtain patterns in metabolic 14CO2 (C-14)O2 evolution.

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NASA NTRS1975

Automated Iodine Monitoring System Development (AIMS)

The operating principle of the automated iodine monitoring/controller system (AIMS) is described along with several design modifications. The iodine addition system is also discussed along with test setups and calibration; a facsimile of the optical/mechanical portion of the iodine monitor was fabricated and tested. The appendices include information on shuttle prototype AIMS, preliminary prime item development specifications, preliminary failure modes and effects analysis, and preliminary operating and maintenance instructions.

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NASA NTRS1985

Managing computer-controlled operations

A detailed discussion of Launch Processing System Ground Software Production is presented to establish the interrelationships of firing room resource utilization, configuration control, system build operations, and Shuttle data bank management. The production of a test configuration identifier is traced from requirement generation to program development. The challenge of the operational era is to implement fully automated utilities to interface with a resident system build requirements document to eliminate all manual intervention in the system build operations. Automatic update/processing of Shuttle data tapes will enhance operations during multi-flow processing.

Plowden, J. B.↗

NASA NTRS1985

Automated mesoscale winds derived from GOES multispectral imagery

An automated technique for extracting mesoscale winds from sequences of GOES visible infrared spin scan radiatiometer (VISSR) image pairs has been developed, tested extensively, and configured for quasi-real time research applications on the Atmospheric Sciences Division's research computing sytem. The entire system of computer codes was successfully vectorized for execution on an array processor resulting in job turnaround in less than 1 hour. An objective quality control system provides much greater than 99 percent accuracy in eliminating questionable wind estimates. Dynamical analysis of cloud wind divergence has revealed temporally consistent convergence centers on the meso-beta scale that are highly correlated with ongoing and future developing convective storms.

Wilson, G. S.↗

NASA NTRS1986

Pilot vehicle interface on the advanced fighter technology integration F-16

This paper focuses on the work load aspects of the pilot vehicle interface in regard to the new technologies tested during AMAS Phase II. Subjects discussed in this paper include: a wide field-of-view head-up display; automated maneuvering attack system/sensor tracker system; master modes that configure flight controls and mission avionics; a modified helmet mounted sight; improved multifunction display capability; a voice interactive command system; ride qualities during automated weapon delivery; a color moving map; an advanced digital map display; and a g-induced loss-of-consciousness and spatial disorientation autorecovery system.

Dana, W. H.↗

NASA NTRS1990

Pressure visualization (PreViz) package version 1.0 user's guide

The Pressure Visualization (PreViz) package is a software tool which merges a wireframe model of the test aircraft with pressure data represented as a series of displacement vectors normal to the aircraft's skin. The PreViz package automates much of the researcher's data reduction effort, reduces the time required to review large amounts of pressure data, presents the data more clearly than tabular listings, and provides a wireframe description for a black and white graphic suitable for a technical publication (the actual graphic images must be created by a local package since PreViz has no graphics capability). Although designed for pressure data, the PreViz package works equally well for any surface property (such as structural loading or skin temperature). Written in ANSI-standard FORTRAN 77 and self-contained, PreViz executes in UNIX, VAX/VMS, and CDC/NOS host environments.

Bingel, Bradford D.↗

NASA NTRS1991

Rotating reactor studies

Undesired gravitational effects such as convection or sedimentation in a fluid can sometimes be avoided or decreased by the use of a closed chamber uniformly rotated about a horizontal axis. In a previous study, the spiral orbits of a heavy or buoyant particle in a uniformly rotating fluid were determined. The particles move in circles, and spiral in or out under the combined effects of the centrifugal force and centrifugal buoyancy. A optimization problem for the rotation rate of a cylindrical reactor rotated about its axis and containing distributed particles was formulated and solved. Related studies in several areas are addressed. A computer program based on the analysis was upgraded by correcting some minor errors, adding a sophisticated screen-and-printer graphics capability and other output options, and by improving the automation. The design, performance, and analysis of a series of experiments with monodisperse polystyrene latex microspheres in water were supported to test the theory and its limitations. The theory was amply confirmed at high rotation rates. However, at low rotation rates (1 rpm or less) the assumption of uniform solid-body rotation of the fluid became invalid, and there were increasingly strong secondary motions driven by variations in the mean fluid density due to variations in the particle concentration. In these tests the increase in the mean fluid density due to the particles was of order 0.015 percent. To a first approximation, these flows are driven by the buoyancy in a thin crescent-shaped depleted layer on the descending side of the rotating reactor. This buoyancy distribution is balanced by viscosity near the walls, and by the Coriolis force in the interior. A full analysis is beyond the scope of this study. Secondary flows are likely to be stronger for buoyant particles, which spiral in towards the neutral point near the rotation axis under the influence of their centrifugal buoyancy. This is because the depleted layer is thicker and extends all the way around the reactor.

Roberts, Glyn O.↗

NASA NTRS1993

The feasibility of producing aluminum-lithium structures for cryogenic tankage applications by laser beam welding

Aluminum-lithium alloys exhibit high strength, high elastic modulus, and low density as well as excellent cryogenic mechanical properties making them ideal material candidates for cryogenic tanks. NASA has proposed the use of 'built-up' structure for panels fabricated into cryogenic tanks replacing current conventional machining. Superplastically formed stiffeners would be joined to sheet (tank skin) that had been roll formed to the radius of the tank in order to produce panels. Aluminum-lithium alloys of interest for producing the built-up structure include alloy 2095-T6 stiffeners to 2095-T8 sheet and alloy 8090-T6 stiffeners to 2090-T83 sheet. Laser welding, with comparable joint properties, offers the following advantages over conventional welding: higher production rates, minimal degradation within the heat affected zones, and full process automation. This study established process parameters for laser beam welding, mechanical property determinations, metallographic characterization, and fabrication of prototype panels. Tensile tests representing partial penetration of the skin alloys provided joint efficiencies between 65 and 77 percent, depending upon alloy and degree of penetration. Results of tension shear tests of lap welds indicated that the combination of 2095-T6 to 2090-T8 exhibited significantly higher weld shear strength at the interface in comparison to welds of 8090-T6 to 2090-T83. The increased shear strength associated with 2095 is believed to be due to the alloy's ability to precipitation strengthening (naturally age) after welding.

Martukanitz, R. P.↗

NASA NTRS1994

Automation for nondestructive inspection of aircraft

We discuss the motivation and an architectural framework for using small mobile robots as automated aids to operators of nondestructive inspection (NDI) equipment. We review the need for aircraft skin inspection, and identify the constraints in commercial airlines operations that make small mobile robots the most attractive alternative for automated aids for NDI procedures. We describe the design and performance of the robot (ANDI) that we designed, built, and are testing for deployment of eddy current probes in prescribed commercial aircraft inspections. We discuss recent work aimed at also providing robotic aids for visual inspection.

Siegel, M. W.↗

NASA NTRS1994

Universal Test Facility

A universal test facility (UTF) for Space Station Freedom is developed. In this context, universal means that the experimental rack design must be: automated, highly marketable, and able to perform diverse microgravity experiments according to NASA space station requirements. In order to fulfill these broad objectives, the facility's customers, and their respective requirements, are first defined. From these definitions, specific design goals and the scope of the first phase of this project are determined. An examination is first made into what types of research are most likely to make the UTF marketable. Based on our findings, the experiments for which the UTF would most likely be used included: protein crystal growth, hydroponics food growth, gas combustion, gallium arsenide crystal growth, microorganism development, and cell encapsulation. Therefore, the UTF is designed to fulfill all of the major requirements for the experiments listed above. The versatility of the design is achieved by taking advantage of the many overlapping requirements presented by these experiments.

Laughery, Mike↗

NASA NTRS1995

Compact, Automated, Frequency-Agile Microspectrofluorimeter

Compact, reliable, rugged, automated cell-culture and frequency-agile microspectrofluorimetric apparatus developed to perform experiments involving photometric imaging observations of single live cells. In original application, apparatus operates mostly unattended aboard spacecraft; potential terrestrial applications include automated or semiautomated diagnosis of pathological tissues in clinical laboratories, biomedical instrumentation, monitoring of biological process streams, and portable instrumentation for testing biological conditions in various environments. Offers obvious advantages over present laboratory instrumentation.

Fernandez, Salvador M.↗

NASA NTRS1996

Flight Test Results from Real-Time Relative Global Positioning System Flight Experiment on STS-69

A real-time global positioning system (GPS) Kalman filter has been developed to support automated rendezvous with the International Space Station (ISS). The filter is integrated with existing Shuttle rendezvous software running on a 486 laptop computer under Windows. In this work, we present real-time and postflight results achieved with the filter on STS-69. The experiment used GPS data from an Osborne/Jet propulsion Laboratory TurboRouge receiver carried on the Wake Shield Facility (WSF) free flyer and a Rockwell Collins 3M receiver carried on the Orbiter. Real time filter results, processed onboard the Shuttle and replayed in near-time on the ground, are based on single vehicle mode operation and on 5 to 20 minute snapshots of telemetry provided by WSF for dual-vehicle mode operation. The Orbiter and WSF state vectors calculated using our filter compare favorably with precise reference orbits determined by the University of Texas Center for Space Research. The lessons learned from this experiment will be used in conjunction with future experiments to mitigate the technology risk posed by automated rendezvous and docking to the ISS.

Park, Young W.↗

NASA NTRS2002

Program Model Checking as a New Trend

This paper introduces a special section of STTT (International Journal on Software Tools for Technology Transfer) containing a selection of papers that were presented at the 7th International SPIN workshop, Stanford, August 30 - September 1, 2000. The workshop was named SPIN Model Checking and Software Verification, with an emphasis on model checking of programs. The paper outlines the motivation for stressing software verification, rather than only design and model verification, by presenting the work done in the Automated Software Engineering group at NASA Ames Research Center within the last 5 years. This includes work in software model checking, testing like technologies and static analysis.

Havelund, Klaus↗

NASA NTRS2006

Three-Function Logic Gate Controlled by Analog Voltage

The figure is a schematic diagram of a complementary metal oxide/semiconductor (CMOS) electronic circuit that performs one of three different logic functions, depending on the level of an externally applied control voltage, V(sub sel). Specifically, the circuit acts as A NAND gate at V(sub sel) = 0.0 V, A wire (the output equals one of the inputs) at V(sub sel) = 1.0 V, or An AND gate at V(sub sel) = -1.8 V. [The nominal power-supply potential (VDD) and logic "1" potential of this circuit is 1.8 V.] Like other multifunctional circuits described in several prior NASA Tech Briefs articles, this circuit was synthesized following an automated evolutionary approach that is so named because it is modeled partly after the repetitive trial-and-error process of biological evolution. An evolved circuit can be tested by computational simulation and/or tested in real hardware, and the results of the test can provide guidance for refining the design through further iteration. The evolutionary synthesis of electronic circuits can now be implemented by means of a software package Genetic Algorithms for Circuit Synthesis (GACS) that was developed specifically for this purpose. GACS was used to synthesize the present trifunctional circuit. As in the cases of other multifunctional circuits described in several prior NASA Tech Briefs articles, the multiple functionality of this circuit, the use of a single control voltage to select the function, and the automated evolutionary approach to synthesis all contribute synergistically to a combination of features that are potentially advantageous for the further development of robust, multiple-function logic circuits, including, especially, field-programmable gate arrays (FPGAs). These advantages include the following: This circuit contains only 9 transistors about half the number of transistors that would be needed to obtain equivalent NAND/wire/AND functionality by use of components from a standard digital design library. If multifunctional gates like this circuit were used in the place of the configurable logic blocks of present commercial FPGAs, it would be possible to change the functions of the resulting digital systems within shorter times. For example, by changing a single control voltage, one could change the function of thousands of FPGA cells within nanoseconds. In contrast, typically, the reconfiguration in a conventional FPGA by use of bits downloaded from look-up tables via a digital bus takes microseconds.

Zebulum, Ricardo↗

NASA NTRS2012

An Automated Sample Processing System for Planetary Exploration

An Automated Sample Processing System (ASPS) for wet chemistry processing of organic materials on the surface of Mars has been jointly developed by Ball Aerospace and the Jet Propulsion Laboratory. The mechanism has been built and tested to demonstrate TRL level 4. This paper describes the function of the system, mechanism design, lessons learned, and several challenges that were overcome.

traditional mechanical components↗