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At least 1,153 records · Page 64

BioSentinel/Mars: Interplanetary Space Radiation Biosensor Experiment in Martian Transit on Mars 2020

Despite significant progress understanding biological radiation effects via terrestrial studies, no terrestrial source duplicates space’s unique radiation environment. Furthermore, no biological experiments have been conducted beyond low Earth orbit since Apollo. Understanding space’s fundamental biological effects requires overcoming these limitations. The BioSentinel 4U payload, under development for flight aboard Exploration Mission-1, measures biological responses to deep space radiation. Traveling to more than 1AU from Earth, BioSentinel/EM-1 will record DNA double-strand breaks (DSBs) repaired using a pathway common to humans and BioSentinel’s bioengineered yeast model organism, responding to as few as one biologically repaired DSB. The BioSentinel/Mars 4U instrument (6-8kg; 5-8W; 0.2-1MB/week) would include eighteen 16-well biosensor fluidic cards, activated biweekly during Mars 2020’s cruise phase, to provide a dose-dependent rate of DSB/repair. The instrument, which includes solid-state sensors for total ionizing dose and linear-energy-transfer spectra, addresses MEPAG SKG-B3 by simultaneously measuring both spectra and biological effects of space radiation. Biological measurements are rendered reliable by independent replicate experiments. The spatio-temporal uniformity of interplanetary galactic cosmic radiation makes BioSentinel/EM1 and BioSentinel/Mars approximate replicates, except for any major differences in solar particle events. Results will be compared to Earth and ISS controls to characterize the radiation/reduced-gravity parameter space by its biological impact.

BioSentinel↗

Nanomanufacturing of Graphene Nanosheets Through Hole Engineering

Facile and scalable fabrication of highly dense and high quality graphene films and articles is extremely attractive for a range of electronic and mechanical applications. Pristine, high quality graphene with its inherent impermeability poses challenges in fabricating dense films and thick parts with high electrical conductivity due to the difficulty in removing trapped air and/or solvents used in various fabrication methods. To overcome this deficiency, nano-holes were intentionally created in pristine graphene (“holey graphene”) with an average diameter of approximately 15 nm. The holes serve as pathways for the rapid removal of gases or liquids and enable the fabrication of dense holey graphene nanostructures. Subsequently, a high temperature process is applied to effectively repair the nano-holes and recover the high quality graphene conjugated network. Through the creation and repair of the nano-holes, dense graphene articles were created that exhibited an ultrahigh conductivity of 2209 S/cm and a high carrier mobility of 673 cm2V-1s-1. This unique processing methodology enables the facile and scalable fabrication of high quality graphene constructs for a variety of applications.

Yanan Chen↗

NASA Wind Tunnel "Bad Days"

Presentation summarizes NASA's most recent emergency repairs as they relate to large wind tunnel operations. These repairs resulted in lessons being learned that are beneficial for sharing with other organizations that operate wind tunnels.

Colantonio, Ron↗

Space Technology Game Changing Development: Synthetic Biological Membrane

The goal of this project is to use synthetic biology techniques to develop biomimetic FO membranes that can self-repair when exposed to chemical and physical damage, as well as radiation and fouling. The self-repair capability is derived from the regenerative characteristics of living systems. Ultimately, this living membrane will be used to extend the operating life and improve the performance of membrane-based life support systems currently being used by NASA.Biological membranes are primarily composed of lipid bilayers. Lipids are organic compounds that, due to their polar hydrophobic fatty acid tails per lipid molecule, are able to self-assemble spontaneously. The lipid bilayer acts as a selective barrier, letting only specific molecules cross the membrane. Recent research into membranes for Next Generation Life Support (NGLS) applications has identified a type of FO membrane that can function as a biomimetic structure.

Flynn, Michael↗

Persistent Assets in Zero-G and on Planetary Surfaces: Enabled by Modular Technology and Robotic Operations

Space operations are on the cusp of a revolutionary new operational paradigm that leverages modular systems and recurring robotic visits to “Persistent Assets” enabling asset maintenance, repair, and enhancement. A “Persistent Asset” is defined here as any zero-g or planetary surface system that benefits from in-space assembly (ISA) or multiple visits for servicing, repairs, and upgrades. This term is an extension of the term “Persistent Platform” used by Ms. Pam Melroy at the Defense Advanced Research Projects Agency to describe the vision of the Agency for a geosynchronous Earth orbiting platform. In this paper, the term “Persistent Asset” is introduced to encompass not only zero-g systems; such as telecommunication platforms, Earth observing science platform, Department of Defense platforms, and scientific telescope systems, but also planetary surface systems that support missions such as human outposts, science stations, and in-situ resource utilization systems. In contrast to the current state of the art, where space systems are typically launched as a single unit and operated without any further physical intervention after launch; future systems will be maintained, enhanced and reconfigured in-situ as new technology becomes available or mission needs change. Visits to the persistent asset can be regularly scheduled or dictated by funding constraints enabling a pay-as-you-go approach, which is largely independent of time-constraints and able to exploit launches of opportunity. In this paper, historical in-space assembly activities which relied heavily on astronaut extra-vehicular activity will be reviewed as well as early robotic assembly activities. These approaches will be contrasted with emerging modular approaches supporting realization of a new Persistent Asset operational paradigm. The paper will define attributes of the Persistent Asset paradigm and illustrate advantages by applying the paradigm to two relevant applications: 1) a large space telescope backing structure and 2) the backbone structure for a solar electric transport vehicle. Finally, recently developed unique Persistent Asset elements (modules, and interface approaches) will be described.

Doggett, William R.↗

Using DNA Damage to Investigate the Individual Variability of Human Sensitivity to Ionizing Radiation

High-LET ionizing radiation is a major occupational health hazard for astronauts, but risk assessment remains elusive due to limited epidemiological data. Identifying genetic factors modulating the individual radiation response may be the most effective strategy to provide individualized risk management for long-duration high-radiation missions. We have started tackling the challenge of predicting individual risks by identifying human genetic loci associated with various radiation sensitivity phenotypes in primary blood mononuclear cells from a relatively large healthy human cohort. To date, we have performed the isolation of PBMCs from 768 subjects of the same ethnicity, and irradiated PBMCs from 576 subjects with 1 and 3 particles/100µm2 of 600 MeV/n 56Fe, 350 MeV/n 40Ar and 350 MeV/n 28Si ions. The phenotypes of interest were: number of radiation-induced foci (or RIFs), CellROX oxidative stress responses and cell death, at 4h and 24h following irradiation. We have observed a significant inter-individual variability at 0 Gy between the 576 studied subjects, with a mean fold difference between the 10% lowest and highest responders of 5.6 of RIFs/cell, 7.9 in mean CellRox intensity, and 9.3 in percentage of dead cells. In order to better assess genetic factors influencing DNA repair, we used a metric previously introduced by our group to sort out radiation sensitivity phenotypes in mice: i.e. the ratio of the first to the second slope of RIFs/cell (between 0 and 1, and between 1 and 3 particle/100µm2). Preliminary data on 192 individuals showed a distribution of low-dose responders (ratio > 1) to high-dose responders (ratio < 1) at 4h of 12%, 55% and 52% respectively for Fe, Ar and Si. The average value for the first and the second slopes was very similar for the two lowest LET (0.10 [-0.26;0.58] and 0.09 [-0.45;0.41] for Ar, 0.07 [-0.27;0.38] and 0.08 [-0.19;0.42] for Si), indicating a linear dose response across both fluence. Fe showed clear saturation for the highest dose with a slope of -0.09 [-0.86;1.51] against 0.68 [-2.21;2.20] for the low dose range, which probably reflects that many PBMCs are beyond repair at the high dose. Note that other significances were found for additional factors such as BMI and age whereas none were found for sex. GWAS will be performed on all phenotypes upon completion of measurements.

Pariset, E.↗

Using DNA Damage to Investigate the Individual Variability of Human Sensitivity to Ionizing Radiation

High-LET ionizing radiation is a major occupational health hazard for astronauts, but risk assessment remains elusive due to limited epidemiological data. Identifying genetic factors modulating the individual radiation response may be the most effective strategy to provide individualized risk management for long-duration high-radiation missions. We have started tackling the challenge of predicting individual risks by identifying human genetic loci associated with various radiation sensitivity phenotypes in primary blood mononuclear cells from a relatively large healthy human cohort. To date, we have performed the isolation of PBMCs from 768 subjects of the same ethnicity, and irradiated PBMCs from 576 subjects with 1 and 3 particles/100µm2 of 600 MeV/n 56Fe, 350 MeV/n 40Ar and 350 MeV/n 28Si ions. The phenotypes of interest were: number of radiation-induced foci (or RIFs), CellROX oxidative stress responses and cell death, at 4h and 24h following irradiation. We have observed a significant inter-individual variability at 0 Gy between the 576 studied subjects, with a mean fold difference between the 10% lowest and highest responders of 5.6 of RIFs/cell, 7.9 in mean CellRox intensity, and 9.3 in percentage of dead cells. In order to better assess genetic factors influencing DNA repair, we used a metric previously introduced by our group to sort out radiation sensitivity phenotypes in mice: i.e. the ratio of the first to the second slope of RIFs/cell (between 0 and 1, and between 1 and 3 particle/100µm2). Preliminary data on 192 individuals showed a distribution of ?low-dose responders? (ratio > 1) to ?high-dose responders? (ratio < 1) at 4h of 12%, 55% and 52% respectively for Fe, Ar and Si. The average value for the first and the second slopes was very similar for the two lowest LET (0.10 [-0.26;0.58] and 0.09 [-0.45;0.41] for Ar, 0.07 [-0.27;0.38] and 0.08 [-0.19;0.42] for Si), indicating a linear dose response across both fluence. Fe showed clear saturation for the highest dose with a slope of -0.09 [-0.86;1.51] against 0.68 [-2.21;2.20] for the low dose range, which probably reflects that many PBMCs are beyond repair at the high dose. Note that other significances were found for additional factors ? such as BMI and age ? whereas none were found for sex. GWAS will be performed on all phenotypes upon completion of measurements.

Pariset, E.↗

Design of a Microgravity Hybrid Inflatable Airlock

Spacewalks, or extra-vehicular activities (EVAs), are a critical component of human space exploration for science activities and habitat construction and maintenance. For NASA's proposed lunar Gateway system, an airlock module is required for vehicle maintenance, repair, and exploration. Traditional airlock structures are fully metallic, with two chambers, known as an equipment lock and a crew lock. The larger volume, called the equipment lock, serves as the storage, logistics and electronics area, while the smaller volume, called the crew lock, serves as the volume to transition from the vacuum of space to the pressurized cabin. A traditional metallic structure design offers mass efficiency for these elements, but cannot offer volume efficiency. The potential to use an inflatable fabric pressure shell supplemented by a metallic support structure allows for efficiency in both mass and volume. Inflatable structures are being used for human habitable space modules, starting with the Bigelow Expandable Activities Module on the International Space Station. They are high-strength fabric-based structures that are compactly stowed for launch and then, once in space, they are expanded and rigidized with internal pressure. They provide significant launch volume savings over metallic structures. For Gateway, a hybrid airlock design is proposed with both metallic and inflatable structural elements, taking advantage of each material's capabilities. A metallic equipment lock serves as both a docking node and provides pressurized volume for pre-EVA activities including pre-breathe and suit donning/doffing. A rigid equipment lock offers stowage space during launch for integrated hardware and suits. Adding an integrated inflatable crew lock provides the volume required for EVAs with minimal use of launch volume. Using dual inflatable crew locks provides redundancy and the capability to move large pieces of equipment into and out of the vehicle for repair and maintenance. The inflatable crew lock is deflated and packaged in the launch shroud and expanded after installation on the Gateway. This packing capability allows additional volume to be added to the equipment lock and fully utilize the capability of the launch vehicle. This report outlines the work completed to design, analyze, and test the systems of a microgravity airlock with inflatable crew locks. In detail, it includes launch vehicles, structural sizing of the metallic equipment lock, the fabric layers of the inflatable crew lock, the internal structure of the crew lock, the space suit interface elements, the crew restraint system, the hatches and pass-throughs, the material and thermal elements, and the crew operations for the usage of the system. This paper is meant to offer a reference design for a hybrid microgravity airlock design for deep space human exploration.

Litteken, Douglas↗

Design of a Microgravity Hybrid Inflatable Airlock

Spacewalks, or extra-vehicular activities (EVAs), are a critical component of human space exploration for science activities and habitat construction and maintenance. For NASA's proposed lunar Gateway system, an airlock module is required for vehicle maintenance, repair, and exploration. Traditional airlock structures are fully metallic, with two chambers, known as an equipment lock and a crew lock. The larger volume, called the equipment lock, serves as the storage, logistics and electronics area, while the smaller volume, called the crew lock, serves as the volume to transition from the vacuum of space to the pressurized cabin. A traditional metallic structure design offers mass efficiency for these elements, but cannot offer volume efficiency. The potential to use an inflatable fabric pressure shell supplemented by a metallic support structure allows for efficiency in both mass and volume. Inflatable structures are being used for human habitable space modules, starting with the Bigelow Expandable Activities Module on the International Space Station. They are high-strength fabric-based structures that are compactly stowed for launch and then, once in space, they are expanded and rigidized with internal pressure. They provide significant launch volume savings over metallic structures. For Gateway, a hybrid airlock design is proposed with both metallic and inflatable structural elements, taking advantage of each material's capabilities. A metallic equipment lock serves as both a docking node and provides pressurized volume for pre-EVA activities including pre-breathe and suit donning/doffing. A rigid equipment lock offers stowage space during launch for integrated hardware and suits. Adding an integrated inflatable crew lock provides the volume required for EVAs with minimal use of launch volume. Using dual inflatable crew locks provides redundancy and the capability to move large pieces of equipment into and out of the vehicle for repair and maintenance. The inflatable crew lock is deflated and packaged in the launch shroud and expanded after installation on the Gateway. This packing capability allows additional volume to be added to the equipment lock and fully utilize the capability of the launch vehicle. This report outlines the work completed to design, analyze, and test the systems of a microgravity airlock with inflatable crew locks. In detail, it includes launch vehicles, structural sizing of the metallic equipment lock, the fabric layers of the inflatable crew lock, the internal structure of the crew lock, the space suit interface elements, the crew restraint system, the hatches and pass-throughs, the material and thermal elements, and the crew operations for the usage of the system. This paper is meant to offer a reference design for a hybrid microgravity airlock design for deep space human exploration.

Litteken, Douglas↗

A Review of Welding in Space and Related Technologies

Deployment of welding and additive manufacturing (AM) technologies in the space environment has the potential to revolutionize how orbiting platforms are designed, manufactured, and assembled. These technologies offer the option for repair of sustained damage to habitat structures on space missions, as astronauts would be able to manufacture new parts (using welding-derived AM processes suitable for use in the external space environment) and weld cracks. An added benefit is that required repairs can be achieved more economically, as new parts need not be shipped from Earth. With further maturation of in-space welding capabilities, astronauts could operate under given standards and weld damaged structures rather than rely on cargo resupply. This Technical Memorandum (TM) begins by reviewing the available literature relevant to welding in space, focusing on solidification, heat and mass transfer, and fluid flows in microgravity. This survey considers research on the effects of welding in microgravity on a material system. The various in-space welding devices that have been previously designed and tested are examined to determine their capabilities and shortcomings, with a focus on the results of their individual welding experiments. Safety measures are discussed to protect the orbiting International Space Station (ISS) and crew during welding operations. Finally, the state of the art is examined by focusing on current approaches to AM and on-orbit welding that are being developed by several companies in conjunction with NASA.

Naden, N.↗

Shockwave/Boundary-Layer Interaction Studies Performed in the NASA Langley 20-Inch Mach 6 Air Tunnel

This paper highlights results from a collaborative study performed by The University of Tennessee Space Institute (UTSI) and NASA Langley Research Center on the Shockwave/Boundary-Layer Interaction (SWBLI) generated by a cylindrical protuberance on a flat plate in a Mach 6 flow. The study was performed in the 20-Inch Mach 6 Air Tunnel at NASA Langley Research Center and consisted of two separate entries. In the first entry, simultaneous high-speed schlieren and high-speed pressure-sensitive paint (PSP) imaging – which was performed for the first time in the 20-Inch Mach 6 facility at NASA Langley – were performed as well as simultaneous high-speed schlieren and oil-flow imaging. In the second entry, the model configuration was modified to increase the size of the interaction region. High-speed schlieren and infrared thermography (IR) surface imaging were performed in this second entry. The goal of these tests was to characterize the SBLI in the presence of a laminar, transitional, and turbulent boundary layer using high-speed optical imaging techniques. AoA = sting angle-of-attack (°) dcylinder = cylinder diameter (mm) dtrip = cylindrical tripping element diameter (mm) Δshock = shock stand-off distance (mm) hcylinder = cylinder height (mm) htrip = cylindrical tripping element height (mm) HSS = high-speed schlieren M∞ = freestream Mach number PSP = pressure-sensitive paint Re∞ = freestream unit Reynolds number (m-1) SWBLI = shockwave/boundary-layer interaction θplate = model plate angle (°) Introduction his paper highlights two experimental entries performed in the 20-Inch Mach 6 Air Blowdown Tunnel at NASA Langley Research Center in collaboration with The University of Tennessee Space Institute (UTSI). The purpose of these entries was to characterize the dynamic shockwave/boundary-layer interaction (SWBLI) between a vertical cylinder on a flat plate and laminar, transitional (XSWBLI), and turbulent (SWTBLI) boundary layers with a freestream Mach number of 6 using non-intrusive optical diagnostics. Experiments performed by Murphree et al.1,2 were among the first to specifically characterize XSWBLI induced by a vertical cylinder on a flat plate geometry using several optical measurement techniques. Recent optical studies of XSWBLI phenomenon have been performed by UTSI at Mach 2 in their low-enthalpy blow wind tunnel3-8 and by Texas A&M University and UTSI at Mach numbers of 6 and 7 in their Adjustable Contour Expansion wind tunnel.9 The experiments described in this paper were intended to complement previous studies by expanding the freestream unit Reynolds number range, Re∞, over which the XSWBLI phenomena has been observed. Additionally these experiments, made possible under NASA’s new facility funding model under the Aeronautics Evaluation and Test Capabilities (AETC) project, promoted collaboration between university and NASA researchers. The initial entry in the 20-Inch Mach 6 Air Tunnel at NASA Langley occurred in December of 2016. Originally, testing was to occur in November of 2016 in the 31-Inch Mach 10 Air Tunnel at NASA Langley. This facility was chosen so that the XSWBLI phenomenon could be observed at much higher Mach numbers than had previously been attempted in ground test experiments. The model selected for this experiment, a 10° half-angle wedge with a sharp leading edge (described in detail in section II.B), had previously been used by Danehy et al. [10] for boundary layer transition studies using the nitric oxide planar laser-induced fluorescence (NO PLIF) flow visualization technique. In that work, it was determined that transition could be induced downstream of a single htrip = 1-mm tall, dtrip = 4-mm diameter cylindrical tripping element and that the streamwise location of the transition could be changed for a single Re∞ by changing the model angle-of-attack (AoA) (see Fig. A3 in Ref. [10] for more details). Based on the findings of that work, a decision was made to use the wedge model with the cylindrical tripping element to trip the boundary layer flow ahead of a cylindrical protuberance in order to achieve a XSWBLI. Unfortunately, the 31-Inch Mach 10 facility had been taken offline for repairs in October of 2016 and a decision was made to move the test to the 20-Inch Mach 6 facility. Since the behavior of the boundary layer with the chosen model configuration had not been studied before in that facility and the available test time was limited, the entry was considered to be exploratory and was used to collect spatially-resolved and time-resolved flow and surface visualization data that would be used to inform a second entry. Test techniques included simultaneous high-speed schlieren (HSS) captured at 160 kHz and high-speed pressure sensitive paint captured at 10 kHz as well as oil flow visualization, captured at 750 Hz. The second entry in the 20-Inch Mach 6 facility occurred in June and July of 2017. In this follow-on test, modifications to the wind tunnel model were made based on observations made during the first entry and included removing the cylindrical tripping element, increasing the size of the cylinder used to induce the SWBLI to increase the size of the interaction while simultaneously improving spatial resolution, and using a swept ramp array, similar to that described in Ref. [11], to trip the flow to turbulence. Simultaneous HSS (captured at 140 kHz, 100 kHz, and 40 kHz) and conventional IR thermography (captured at 30 Hz) imaging were performed simultaneously in this follow-on entry. This paper is intended to serve as a summary of the work performed during these two entries, to detail lessons learned from each entry, and to highlight some of the datasets acquired. Details on the experimental setup, model configuration, and techniques used are provided. Papers providing a more rigorous analysis of data acquired during the second entry, including statistical, spectral, and modal decomposition methods, can be found in Refs. [12,13]. An entry examining XSWBLI in the 31-Inch Mach 10 Blowdown Wind Tunnel facility is currently planned for mid-to-late calendar year 2019, pending the success of facility repairs. The work performed and described in this paper and the upcoming entry in the 31-Inch Mach 10 facility at NASA Langley have been made possible by NASA’s new facility funding model under the Aeronautics Evaluation and Test Capabilities (AETC) project. Wind Tunnel Facility All experiments discussed in this paper were performed in the 20-Inch Mach 6 Air Tunnel at NASA Langley Research Center. Specific details pertaining to this facility can be found in Refs. [14,15], with only a brief description of the facility provided here. For both entries, the nominal freestream unit Reynolds number was varied between 1.8×106 m-1 (0.5×106 ft-1) and 26.3×106 m-1 (8×106 ft-1). The nominal stagnation pressure was varied between 0.21 MPa and 3.33 MPa and the nominal stagnation temperature was varied between 480 K and 520 K to achieve the desired Re∞ condition. For all runs, the nominal freestream Mach number was 6. The nearly square test section is 520.7-mm (20.5-inches) wide by 508-mm (20-inches) high. Two 431.8-mm (17-inch) diameter windows made of Corning 7940, Grade 5F schlieren-quality glass serve as the side walls of the tunnel and provide optical access for the high-speed schlieren measurements. A rectangular window made of the same material as the side windows served as the top wall of the test section and provided optical access for the high-speed PSP and oil flow measurements. For the second entry, this top window was replaced with a Zinc Selenide (ZnSe) window with an anti-reflection coating capable of passing IR wavelengths between 8μm and 12μm with greater than 98% transmittance. The model was sting supported by a strut attached to a hydraulic system that allows for the model pitch angle to be adjusted between -5° to +55°. For the first entry, an initial pitch/pause sweep of the model AoA was performed to observe the resulting SWBLI. Ultimately, however, the sting pitch angle for this entry was fixed at +10.0° so that the angle of the top surface of the wedge relative to the streamwise axis of the tunnel (referred to herein as the plate angle, θplate), was θplate = 0°. For the second entry, θplate = 0° and θplate = -13.25° were initially tested with the swept ramp array (discussed in the following section) to determine which orientation produced conditions most favorable for XSWBLI to occur based on the heating signatures observed over the top surface of the model in the IR thermography images. Based on these initial tests, θplate = -13.25° was set for the remainder of the runs in the second entry. For both entries, any model changes were performed in a housing located beneath the closed test section. Prior to performing a run of the tunnel, the housing was sealed and the tunnel started. Once the appropriate freestream conditions were achieved, the model was injected into the test section using a hydraulic injection system. B. Model Geometry For all runs, a 10° half-angle (20° full-angle) wedge model with a sharp leading edge was used. The model is described in detail in Refs. [10,16]. The top surface of the sharp leading edge of the model extended 47.8 mm from its upstream-most edge to a junction with the upstream edge of a stainless steel top plate that then extended an (a) (c) (b) Fig. 1 (a) Schematic of top surface of wedge model with gas seeding insert, (b) perspective view of the model in the 20-Inch Mach 6 tunnel with centerline pressure orifices on sharp leading edge, and (c) a perspective view of the model with stainless steel (top) and SLA middle insert (bottom) during the first entry. Flow occurs from left to right.

Bathel, Brett F.↗

Persistent Assets in Zero-G and on Planetary Surfaces: Enabled by Modular Technology and Robotic Operations

Space operations are on the cusp of a revolutionary new operational paradigm that leverages modular systems and recurring robotic visits to “Persistent Assets” enabling asset maintenance, repair, and enhancement. A “Persistent Asset” is defined here as any zero-g or planetary surface system that benefits from in-space assembly (ISA) or multiple visits for servicing, repairs, and upgrades. This term is an extension of the term “Persistent Platform” used by Ms. Pam Melroy at the Defense Advanced Research Projects Agency to describe the vision of the Agency for a geosynchronous Earth orbiting platform. In this paper, the term “Persistent Asset” is introduced to encompass not only zero-g systems; such as telecommunication platforms, Earth observing science platform, Department of Defense platforms, and scientific telescope systems, but also planetary surface systems that support missions such as human outposts, science stations, and in-situ resource utilization systems. In contrast to the current state of the art, where space systems are typically launched as a single unit and operated without any further physical intervention after launch; future systems will be maintained, enhanced and reconfigured in-situ as new technology becomes available or mission needs change. Visits to the persistent asset can be regularly scheduled or dictated by funding constraints enabling a pay-as-you-go approach, which is largely independent of time-constraints and able to exploit launches of opportunity. In this paper, historical in-space assembly activities which relied heavily on astronaut extra-vehicular activity will be reviewed as well as early robotic assembly activities. These approaches will be contrasted with emerging modular approaches supporting realization of a new Persistent Asset operational paradigm. The paper will define attributes of the Persistent Asset paradigm and illustrate advantages by applying the paradigm to two relevant applications: 1) a large space telescope backing structure and 2) the backbone structure for a solar electric transport vehicle. Finally, recently developed unique Persistent Asset elements (modules, and interface approaches) will be described.

William R Doggett↗

A Review of Unmanned Aerial Vehicle Technology in Power Line Inspection

The electric power industry is one of the heaviest adopters of Unmanned Aerial Vehicles (UAV) technology, utilizing their versatility to enhance power line maintenance programs. For reliable power grids, routine maintenance operations and rapid repair operations are required across substantial geographical distances. Both maintenance and repair decisions are driven by assessment operations, such as inspections of mechanical structures with visible-band sensors, inspections for the presence of high voltage coronas and hot spots with multispectral sensors, and surveying of equipment and adjacent features (particularly vegetation) with photogrammetric and Light Detection and Ranging (LiDAR) sensors. Assessment was historically accomplished with manned helicopter flights or foot patrols. Recently, this critical economic segment harnessed advances in Unmanned Aerial Systems (UAS)technology to accomplish assessment tasks with faster results, lower cost, and higher levels of safety than historical methods. Adoption of UAVs in high-voltage electric power transmission activities is well underway. Adoption of UAVs for low voltage distribution activities is still emerging, with the important exception of post-storm damage assessment following major hurricanes (Harvey and Maria in 2017 and Michael in 2018). This report reviews the broad UAS adoption in high-voltage electric power transmission operations and early attempts at adoption in distribution operations. The ability to fly beyond visual line of sight (BVLOS) may increase the advantages of UAV inspection over former options, and in the United States, regulators have approved two pilot projects to demonstrate BVLOS methods and their benefits in operating and maintaining the power grid.

UAV↗

Printed Flexible Sensors for NASA Applications

As human spaceflight pushes beyond Low Earth Orbit (LEO), resupply of consumables becomes a significant challenge. One solution to this problem is In-Space Manufacturing (ISM), the capability to perform on-demand manufacturing and repair of consumables in an in-space environment. ISM offers significant flexibility to missions as it allows for a high degree of tailorability and reduction in launch mass. Leveraging advancements in fabrication, repair and recycling, ISM provides a highly sustainable and affordable solution to Exploration mission operations and logistics. In this talk, advances in printed electronics and sensors, ranging from nanomaterial ink development and hands-free fabrication methodologies to devices will be presented. Applications presented will include sensors for crew health monitoring, structural health monitoring and power generation.

sensors↗

In-Space Manufacturing to Support Human Spaceflight

As human spaceflight pushes beyond Low Earth Orbit (LEO), resupply of consumables becomes a significant challenge. One solution to this problem is In-Space Manufacturing (ISM), the capability to perform on-demand manufacturing and repair of consumables in an in-space environment. ISM offers significant flexibility to missions as it allows for a high degree of tailor ability and reduction in launch mass. Leveraging advancements in fabrication, repair and recycling, ISM provides a highly sustainable and affordable solution to exploration mission operations and logistics. In this talk, advances in printed electronics and sensors, ranging from nanomaterial ink development and hands-free fabrication methodologies to devices will be presented. Applications presented will include sensors for crew health monitoring along with supporting electronics. In the future, these devices will be fabricated and characterized on the International Space Station and the approach will be evaluated for future in-space manufacturing to support human spaceflight.

nanotechnology↗

AMMPER: Agent-based Model for Microbial Populations Exposed to Radiation

Exposure of microbial populations to galactic cosmic radiation (GCR) in the deep-space radiation environment may lead to intracellular damage that compromises the ability of cells to repair and replicate. While simulation programs of deep-space radiation do exist, they focus primarily on single-cell damage, rather than population-wide effects. In this work, a new application and graphical user interface, Agent-Based Model for Microbial Populations Exposed to Radiation (AMMPER) is presented, which simulates the effects of proton-based GCR on Saccharomyces cerevisiae population growth. AMMPER consists of a 50x50x50 µm simulation space, analogous to an aqueous culture medium with non-limiting nutrient and pH buffering, in a microwell plate or microfluidic culture card. This model utilizes Relativistic Ion Tracks (RITRACKS) to create detailed track structures of the radiation traversals. AMMPER then calculates the radiation dose present at each cell, and subsequently determines the damage (chromosomal aberrations, oxidative stress, etc.) and resulting loss of cell viability from both primary and secondary radiative effects. Through implementing cell replication, repair, damage, and death, the effect of radiation exposure on the population growth can be determined. With AMMPER, long-duration effects of the deep space environment on entire populations can be determined and used to assess the feasibility of sustaining life in space.

Amrita Singh↗

Printed Sensors and Electronics for Sustained Human Spaceflight

As human spaceflight pushes beyond Low Earth Orbit (LEO), resupply of consumables becomes a significant challenge. One solution to this problem is In-Space Manufacturing (ISM), the capability to perform on-demand manufacturing and repair of consumables in an in-space environment. ISM offers significant flexibility to missions as it allows for a high degree of tailorability and reduction in launch mass. Leveraging advancements in fabrication, repair and recycling, ISM provides a highly sustainable and affordable solution to Exploration mission operations and logistics. In this talk, advances in printed electronics and sensors, ranging from nanomaterial ink development and hands-free fabrication methodologies to devices will be presented.

In Space Manufacturing↗

Investigating Biological Responses to Deep Space Radiation for Missions Beyond Low Earth Orbit (LEO) using Yeast

To enable long-term spaceflight missions and establish habitation on the Moon and Mars, we require a comprehensive understanding of the effects of chronic deep space radiation exposure on humans. BioSentinel is NASA’s first biological CubeSat to venture beyond Low Earth Orbit (LEO). It utilizes Saccharomyces cerevisiae (budding yeast) as a model organism to study biological responses to deep space radiation. Yeast share significant genetic homology with humans, including basic cellular metabolism and DNA repair mechanisms. In addition, unlike human cell cultures, yeast can survive the duration and constraints of a deep space mission. BioSentinel measures biological responses using an optical system and alamarBlue oxidation-reduction (redox) dye. Two strains of yeast are studied - a wild-type and a rad51 mutant strain that is deficient in DNA repair. Changes in metabolism and growth are monitored throughout the nominal 6-month mission. Preliminary tests indicate a significant change in the alamarBlue response to low-dose ionizing radiation (IR). Additionally, rad51 cells have shown an IR dose-dependent decrease in glucose uptake and accumulation of oxidized NADH (NAD+). These biomolecules are involved in reactions responsible for basic cell processes, including growth and development, signaling, and respiration. The current study expanded upon previous data by exposing yeast to deep space-relevant radiation. Glucose and NADH/NAD+ assays were conducted on yeast subjected to varying dosages of high-energy Fe-56 and simulated galactic cosmic rays (GCRs). The resulting data was analyzed using Excel and GraphPad Prism. A particular focus was to identify biomolecules resulting from aerobic respiration, which requires the presence of oxygen, or anaerobic processes. As long-term spaceflight missions draw near, it is increasingly important to characterize biological processes affected by the conditions of deep space. Studying biomolecular damage caused by deep space radiation may enable the development of engineering controls or biomedical therapeutics that mitigate health complications for future astronauts.

Kyra Keenan↗