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At least 1,135 records · Page 63

Visual examination apparatus

An automated visual examination apparatus for measuring visual sensitivity and mapping blind spot location including a projection system for displaying to a patient a series of visual stimuli. A response switch enables him to indicate his reaction to the stimuli, and a recording system responsive to both the visual stimuli per se and the patient's response. The recording system thereby provides a correlated permanent record of both stimuli and response from which a substantive and readily apparent visual evaluation can be made.

Haines, R. F.↗

Biomedical technology transfer: Applications of NASA science and technology

The major efforts of the Stanford Biomedical Applications Team Program at the Stanford University School of Medicine for the period from October 1, 1975 to September 31, 1976 are covered. A completed EMG biotelemetry system which monitors the physiological signals of man and animals in space related research is discussed. The results of a pilot study involving lower body negative pressure testing in cardiac patients has been completed as well as the design and construction of a new leg negative pressure unit for evaluating heart patients. This technology utilizes vacuum chambers to stress the cardiovascular system during space flight. Laboratory tests of an intracranial pressure transducer, have been conducted. Extremely stable long term data using capacative pressure sensors has lead to the order of commercially manufactured monitoring systems base. Projects involving commercialization are: flexible medical electrodes, an echocardioscope, a miniature biotelemetry system, and an on-line ventricular contour detector.

Source record↗

Biomedical technical transfer. Applications of NASA science and technology

Lower body negative pressure testing in cardiac patients has been completed as well as the design and construction of a new leg negative unit for evaluating heart patients. This technology is based on NASA research, using vacuum chambers to stress the cardiovascular system during space flight. Additional laboratory tests of an intracranial pressure transducer, have been conducted. Three new biomedical problems to which NASA technology is applicable are also identified. These are: a communication device for the speech impaired, the NASA development liquid-cooled garment, and miniature force transducers for heart research.

Source record↗

Magnetic electrical connectors for biomedical percutaneous implants

A biomedical percutaneous connector is described which includes a socket having an enlarged disk shaped base portion for being implanted below the patient's skin and cylindrical portion which is integral with the base portion and extends outwardly of the skin. A conical recess in an upper end of the cylindrical portion has a magnet located in the base. Inclined conductive strips are carried on an upper end of the cylindrical portion to which electrical conductors are attached and extend into the patient's body. A complementary shaped plug which also has electrical contacts provided thereon is adapted to fit within the conical recess of the socket. The plug is held in the socket by magnetic force.

Owens, L. J.↗

Exercise stress testing

Positive maximum stress tests in the management of coronary patients are discussed. It is believed that coronary angiography would be the ultimate test to predict the future of patients with coronary heart disease. Progression of angina, myocardial infarction, and death due to heart disease were analyzed.

Schuster, B.↗

Feasibility study on the design of a probe for rectal cancer detection

Rectal examination techniques are considered in terms of detection capability, patient acceptance, and cost reduction. A review of existing clinical techniques are considered in terms of detection capability, patient acceptance, and cost reduction. A review of existing clinical techniques and of relevant aerospace technology included evaluation of the applicability of visual, thermal, ultrasound, and radioisotope modalities of examination. The desired improvements can be obtained by redesigning the proctosigmoidoscope to have reduced size, additional visibility, and the capability of readily providing a color photograph of the entire rectosigmoid mucosa in a single composite view.

Anselm, V. J.↗

The Stanford-Ames portable echocardioscope - A case study in technology transfer

The paper describes a lightweight portable battery-powered echocardioscope fabricated largely from readily available components. The transducer contains a piezoelectric crystal which acts as both an ultrasound pulse emitter and echo receiver, and the oscilloscope is of modular construction. The oscilloscope display can be produced in any of three different modes: A-mode, B-mode, and M-mode (time-motion) by sweeping the intensified points of light of the B-mode display vertically along the oscilloscope face. The resulting display can be photographed in a time exposure, thus providing a hardcopy record for the patient's chart or physician's records. The device is clinically validated on both normal subjects and patients by experienced echocardiographers.

Schmidt, G.↗

Separation of lymphocytes by electrophoresis under terrestrial conditions and at zero gravity, phase 3

Electrophoretic mobilities (EPM) of peripheral lymphocytes were studied from normal subjects, chronic hemodialysis patients and kidney transplant recipients. A technique to separate B lymphocytes and null cells from non-T lymphocyte preparation was developed. The experiments were designed to determine which subpopulation of the non-T lymphocytes is primarily affected and shows a decreased EPM in chronic hemodialysis patients and kidney transplant recipients.

Rubin, A. L.↗

Emptying patterns of the lung studied by multiple-breath N2 washout

Changes in the nitrogen concentration seen during the single-breath nitrogen washout reflect changes in relative flow (ventilation) from units with differing ventilation/volume ratios. The multiple-breath washout provides sufficient data on ventilation for units with varying ventilation/volume ratios to be plotted as a function of the volume expired. Flow from the dead space may also be determined. In young normals the emptying patterns are narrow and unimodal throughout the alveolar plateau with little or no flow from the dead space at the end of the breath. Older normals show more flow from the dead space, particularly toward the end of the breath, and some show a high ventilation/volume ratio mode early in the breath. Patients with obstructive lung disease have a high flow from the dead space which is present throughout the breath. A well ventilated mode at the end of the breath is seen in some obstructed subjects. Patients with cystic fibrosis showed a poorly ventilated mode appearing at the end of the breath as well as a very high dead space.

Lewis, S. M.↗

The child in coma

Children in coma continue to pose medical, social, economic, ethical, moral, and legal problems. Modern life-support technology has aggravated these problems. Coma is viewed as a pathological state of unconsciousness from which the patient has not achieved arousal, and which calls for vigorous action to help him regain consciousness. There are two variables that have an especially important bearing on the ability to achieve arousal. These are: the character of the brain injury that caused the coma, and environmental factors that affect the patient after the injury.

Lewinn, E. B.↗

Portable device for detection of petit mal epilepsy

A portable device that analyzes the electroencephalogram to determine if petit mal epilepsy waveforms are present is developed and tested. Clinicians should find it useful in diagnosing seizure activity of their patients. The micropower, battery-operated, portable device indicates a seizure has occurred if three criteria are satisfied: (1) frequencies of 2.5-7 Hz, (2) large-amplitude waves, and (3) minimum number of waves per second. Levels and counts are adjustable, thus insuring high reliability against noise artifacts and permitting each subject to be individually fitted. The device has shown promise in giving the patient a possible mechanism of seizure control or suppression.

Smith, R. G.↗

Preliminary results of fast neutron treatments in carcinoma of the pancreas

A group of 30 patients with adenocarcinoma of the pancreas including some patients with very advanced disease, were treated with the so-called mixed beam modality employing photon treatments three times per week and neutron treatments twice a week. Two hundred Rads or equivalent Rads (RBE 3.3) were given in daily fractions aiming at a total dose of 6000 Rads in 6 to 8 weeks. The treatments were well tolerated and significant palliation was achieved in 26 to 30 cases. Twelve months survival was 33 percent with a median survival of 7 months or 210 days. Treatment techniques and localization procedures are discussed.

Gahbauer, R.↗

Lightweight Face Mask

Lightweight face mask originally developed to protect epileptic patients during seizures could have many other medical and nonmedical applications such as muscular distrophy patients, football linesmen and riot-control police. Masks are extremely lightweight, the lightest of the configurations weighing only 136 grams.

Cason, W. E. I.↗

Objective appraisal of tolerance to ventriculography with various radiocontrast media (according to electronystagmography data)

The vestibulo oculomotor reflex (nystagmus) was recorded by means of electronystagmography in 33 neurosurgical patients in dynamics prior to and after ventriculography. For contrasting the ventricular system a water soluble medium (Conrey, dimer X or Amipak) was used in 18 patients and contrast mixtures of water soluble agents in combination with Myodil emulsion in 15. It was established that after ventriculography with water soluble media the trunk vestibular reactions in all types of nystagmus grew frequently and sharply and the vestibulovegetative reactions increased markedly.

Blagoveshchenskaya, N. S.↗

NASA: Biomedical applications team

The status of projects involving the adaptation of NASA technologies for medical purposes is reviewed. Devices for the measurement of joint deformation of arthritic hands, the development of an artificial pancreas, provision of an auditory signal to avert epileptic seizures, are described along with the control of medication levels, a compressed air tank to supply power for field dentistry, and an electroencephalogram monitor. The use of the Lixiscope as a portable fluoroscope, thermal laminates for hand and foot warmers for patients with Raynaud's syndrome, and the use of absorptive coatings for instruments for controlling medication levels are described. The applicability of occupation health and safety practices to industry, computerized patient scheduling, impregnation of the common facial tissue with an agent for killing respiratory viruses, commercial applications of anthropometric data, and multispectral image analysis of the skin as a diagnostic tool are reviewed.

Source record↗

Computer Analysis of Eye Blood-Vessel Images

Technique rapidly diagnoses diabetes mellitus. Photographs of "whites" of patients' eyes scanned by computerized image analyzer programmed to quantify density of small blood vessels in conjuctiva. Comparison with data base of known normal and diabetic patients facilitates rapid diagnosis.

Wall, R. J.↗

Generation-V dual-Purkinje-image eyetracker

Major advances characterize the Generation-V dual-Purkinje-image eyetracker compared with the Generation-III version previously described. These advances include a large reduction in size, major improvements in frequency response and noise level, automatic alignment to a subject, and automatic adjustment for different separation between the visual and optic axes, which can vary considerably from subject to subject. In a number of applications described in the paper, the eyetracker is coupled with other highly specialized optical devices. These applications include accurately stabilizing an image on a subject's retina; accurately simulating a visually dead retinal region (i.e., a scotoma) of arbitrary shape, size, and position; and, for clinical purposes, stabilizing the position of a laser coagulator beam on a patient's retina so that the point of contact is unaffected by the patient's own eye movements.

Crane, H. D.↗

Implantable, Ingestible Electronic Thermometer

Small quartz-crystal-controlled oscillator swallowed or surgically implanted provides continuous monitoring of patient's internal temperature. Receiver placed near patient measures oscillator frequency, and temperature inferred from previously determined variation of frequency with temperature. Frequency of crystal-controlled oscillator varies with temperature. Circuit made very small and implanted or ingested to measure internal body temperature.

Kleinberg, Leonard↗