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At least 1,099 records · Page 61
All sourcesNASA NTRSDOE OSTI
DOE OSTI2014

Feasibility of Multimodal Deformable Registration for Head and Neck Tumor Treatment Planning

Purpose: To investigate the feasibility of using deformable registration in clinical practice to fuse MR and CT images of the head and neck for treatment planning. Method and Materials: A state-of-the-art deformable registration algorithm was optimized, evaluated, and compared with rigid registration. The evaluation was based on manually annotated anatomic landmarks and regions of interest in both modalities. We also developed a multiparametric registration approach, which simultaneously aligns T1- and T2-weighted MR sequences to CT. This was evaluated and compared with single-parametric approaches. Results: Our results show that deformable registration yielded a better accuracy than rigid registration, without introducing unrealistic deformations. For deformable registration, an average landmark alignment of approximatively 1.7 mm was obtained. For all the regions of interest excluding the cerebellum and the parotids, deformable registration provided a median modified Hausdorff distance of approximatively 1 mm. Similar accuracies were obtained for the single-parameter and multiparameter approaches. Conclusions: This study demonstrates that deformable registration of head-and-neck CT and MR images is feasible, with overall a significanlty higher accuracy than for rigid registration.

62 RADIOLOGY AND NUCLEAR MEDICINE↗
DOE OSTI2025

Unraveling the Mechanism of Interfacial Charge Transfer and Photoresponsivity of WS 2 Quantum Dots/MoS 2 (0D–2D) Heterostructure-Based Transistors

To assess the efficacy of a mixed-dimensional van der Waals (vdW) heterostructure in modulating the optoelectronic responses of nanodevices, the charge transport properties of the transition-metal dichalcogenide (TMD)-based heterostructure comprising zero-dimensional (0D) WS 2 quantum dots (QDs) and two-dimensional (2D) MoS 2 flakes are critically analyzed. Herein, a facile strategy was materialized in developing an atomically thin phototransistor assembled from mechanically exfoliated MoS 2 and WS 2 QDs synthesized using a one-pot hydrothermal route. The amalgamated photodetectors exhibited a high responsivity of ∼8000 A/W at an incident power of 0.05 nW of white light, surpassing that of the pristine MoS 2 devices. Furthermore, the detectivity of pristine MoS 2 , which was on the order of 10 10 , increased to 10 12 Jones for the WS 2 QDs/MoS 2 heterostructure photodetector, outperforming other WS 2 -based materials. The quasiparticle band gap and density of states (DOS) are further analyzed to elucidate the photophysics of the WS 2 QD/MoS 2 hybrid assembly. The difference in the work function between MoS 2 and WS 2 QDs gives rise to an electric field across the 0D–2D interface, facilitating effective charge separation and migration and contributing to the enhancement of photoresponsivity. The analysis of optical responses using density functional theory (DFT) revealed stronger absorption and less reflection over a broader spectrum of wavelengths for the heterostructure compared to the pristine materials. The estimated optical conductivity aligns well with the experimentally predicted maximum photoresponsivity under visible light, which is attributed to the high absorbance of 2D MoS 2 . In conclusion, combining diverse spectroscopic and imaging techniques with quantum simulation provides insights that clarify the pertinence of 0D–2D TMDs in designing phototransistors.

WS2 QDs/MoS2 heterostructure↗
DOE OSTI2024

Nuclear imaging to diagnose and correct target-driver registration at high-repetition-rate for improved reactor efficiency

Inertial Confinement Fusion produces energy from a burning plasma lasting a fraction of a nanosecond. Power plant designs based on Inertial Fusion Energy (IFE) will need to ignite targets 1-10 times a second, fired as projectiles into a chamber and delivering the driver to the target location. Driver asymmetry is known to impact ICF experiments at gain near unity and remains a candidate for primary yield degradation, and therefore fusion power plant energy output, for high-gain target designs. For a Fusion Power Plant (FPP), continuous and real-time monitoring of target performance provides an opportunity to stabilize or correct the target-driver registration. This requires x-ray and neutron imaging with a large field-of-view, sufficiently high resolution, fast analysis and to subtend a minimal solid angle. We introduce design criteria for such an imaging system that uses a coded aperture and time-gated, lens-coupled scintillators as a viable solution and outline the research steps required to field such a system. Integrating the imaging system into an IFE power plant as part of an active feedback loop could increase average power output by reducing the failure rate due to mis-aligned drivers with respect to the target.

46 INSTRUMENTATION RELATED TO NUCLEAR SCIENCE AND ↗
NASA NTRS1973

Experimental test of magnetospheric models.

The barium cloud injection deep into the magnetosphere of Sept. 21, 1971, has revealed that the quiet-time near-equatorial nightside magnetic field is significantly different from that predicted by existing quite-time models. The influence of currents flowing on or near the geomagnetic equator gives the field a more tail-like structure at a distance as close as 5 earth radii. Several models have been tried out to obtain a best fit to the experimental observations of the shape of the field-aligned ion cloud. Although this method does not lead to a unique solution, the most acceptable option emerging from this analysis is a quiet-time tilted image-dipole model with a Williams-Mead tail field and a disclike ring current on the geomagnetic equator.

Barish, F. D.↗
NASA NTRS1986

Mesoscale waves as a probe of Jupiter's deep atmosphere

Images from the Voyager north/south mapping sequences were searched for waves. A remarkable class of mesoscale waves was identified, with the following features: (1) the wavetrains are usually aligned zonally, i.e., wavecrests are north-south; (2) the average wavelength is 300 km with a standard deviation of only 20%; (3) the wavetrains are long; (4) the waves occur within 25 degrees of the equator, the bulk being at the equator itself; (5) the waves are centered at the extrema (in latitude) of the zonal flow; and (6) the meridional extent of the waves is typically 1 degree of latitude. These observations are interpreted as evidence of gravity waves propagating vertically within a leaky duct. A three-level model is assumed composed of a stable duct which extends up to the base of the NH3 cloud deck near 600 mb. Above this is a thin wave-trapping region characterized by a Richardson number Ri less than 1/4 and containing a critical level, where the local value of the zonal flow velocity equals the phase speed of the wave. This in turn is overlain by a stable region, representing the tropopause region and stratosphere.

Flaser, F. M.↗
NASA NTRS1990

Ultrasonic and radiographic evaluation of advanced aerospace materials: Ceramic composites

Two conventional nondestructive evaluation techniques were used to evaluate advanced ceramic composite materials. It was shown that neither ultrasonic C-scan nor radiographic imaging can individually provide sufficient data for an accurate nondestructive evaluation. Both ultrasonic C-scan and conventional radiographic imaging are required for preliminary evaluation of these complex systems. The material variations that were identified by these two techniques are porosity, delaminations, bond quality between laminae, fiber alignment, fiber registration, fiber parallelism, and processing density flaws. The degree of bonding between fiber and matrix cannot be determined by either of these methods. An alternative ultrasonic technique, angular power spectrum scanning (APSS) is recommended for quantification of this interfacial bond.

Generazio, Edward R.↗
NASA NTRS1993

Monitoring of the Greenland Ice Sheet using ERS-1 synthetic aperture radar imagery

ERS-1 Synthetic Aperture Radar (SAR) imagery is shown to be suitable for monitoring the climate of the Greenland ice sheet and for measuring changes in its marginal position. Four distinct hydrologic zones are easily recognized. Zone boundaries align closely with elevation. Seasonal changes in at least one of these zones indicate that late Winter is a better time than late Summer for the collection of images intended for long term monitoring. Subtle variations of the backscatter intensity from the highest portions of the ice sheet where melting never occurs are believed to indicate surface topography.

Bindschadler, Robert↗
NASA NTRS2007

SOHO-Ulysses Coordinated Studies During the Two Extended Quadratures and the Radial Alignment of 2007-2008

During quadrature, plasma seen on the limb of the Sun, along the radi al direction to Ulysses, by SOHO or STEREO can be sampled in situ as lt later passes Ulysses. A figure shows a coronagraph image, the rad ial towards Ulysses at 58 deg. S. and the SOHO/UVCS slit positions d uring one set of observations. A CME subsequently occurred and passed Ulysses (at 3/4 AU) 15 days later.

Suess, S. T.↗
NASA NTRS2008

Pattern-Recognition System for Approaching a Known Target

A closed-loop pattern-recognition system is designed to provide guidance for maneuvering a small exploratory robotic vehicle (rover) on Mars to return to a landed spacecraft to deliver soil and rock samples that the spacecraft would subsequently bring back to Earth. The system could be adapted to terrestrial use in guiding mobile robots to approach known structures that humans could not approach safely, for such purposes as reconnaissance in military or law-enforcement applications, terrestrial scientific exploration, and removal of explosive or other hazardous items. The system has been demonstrated in experiments in which the Field Integrated Design and Operations (FIDO) rover (a prototype Mars rover equipped with a video camera for guidance) is made to return to a mockup of Mars-lander spacecraft. The FIDO rover camera autonomously acquires an image of the lander from a distance of 125 m in an outdoor environment. Then under guidance by an algorithm that performs fusion of multiple line and texture features in digitized images acquired by the camera, the rover traverses the intervening terrain, using features derived from images of the lander truss structure. Then by use of precise pattern matching for determining the position and orientation of the rover relative to the lander, the rover aligns itself with the bottom of ramps extending from the lander, in preparation for climbing the ramps to deliver samples to the lander. The most innovative aspect of the system is a set of pattern-recognition algorithms that govern a three-phase visual-guidance sequence for approaching the lander. During the first phase, a multifeature fusion algorithm integrates the outputs of a horizontal-line-detection algorithm and a wavelet-transform-based visual-area-of-interest algorithm for detecting the lander from a significant distance. The horizontal-line-detection algorithm is used to determine candidate lander locations based on detection of a horizontal deck that is part of the lander.

Huntsberger, Terrance↗
NASA NTRS2010

NASA Tech Briefs, October 2010

Topics covered include: Hybrid Architecture Active Wavefront Sensing and Control; Carbon-Nanotube-Based Chemical Gas Sensor; Aerogel-Positronium Technology for the Detection of Small Quantities of Organic and/or Toxic Materials; Graphene-Based Reversible Nano-Switch/Sensor Schottky Diode; Inductive Non-Contact Position Sensor; High-Temperature Surface-Acoustic-Wave Transducer; Grid-Sphere Electrodes for Contact with Ionospheric Plasma; Enabling IP Header Compression in COTS Routers via Frame Relay on a Simplex Link; Ka-Band SiGe Receiver Front-End MMIC for Transponder Applications; Robust Optimization Design Algorithm for High-Frequency TWTs; Optimal and Local Connectivity Between Neuron and Synapse Array in the Quantum Dot/Silicon Brain; Method and Circuit for In-Situ Health Monitoring of Solar Cells in Space; BGen: A UML Behavior Network Generator Tool; Platform for Post-Processing Waveform-Based NDE; Electrochemical Hydrogen Peroxide Generator; Fabrication of Single, Vertically Aligned Carbon Nanotubes in 3D Nanoscale Architectures; Process to Create High-Fidelity Lunar Dust Simulants; Lithium-Ion Electrolytes Containing Phosphorous-Based, Flame-Retardant Additives; InGaP Heterojunction Barrier Solar Cells; Straight-Pore Microfilter with Efficient Regeneration; Determining Shear Stress Distribution in a Laminate; Self-Adjusting Liquid Injectors for Combustors; Handling Qualities Prediction of an F-16XL-Based Reduced Sonic Boom Aircraft; Tele-Robotic ATHLETE Controller for Kinematics - TRACK; Three-Wheel Brush-Wheel Sampler; Heterodyne Interferometer Angle Metrology; Aligning Astronomical Telescopes via Identification of Stars; Generation of Optical Combs in a WGM Resonator from a Bichromatic Pump; Large-Format AlGaN PIN Photodiode Arrays for UV Images; Fiber-Coupled Planar Light-Wave Circuit for Seed Laser Control in High Spectral Resolution Lidar Systems; On Calculating the Zero-Gravity Surface Figure of a Mirror; Optical Modification of Casimir Forces for Improved Function of Micro- and Nano-Scale Devices; Analysis, Simulation, and Verification of Knowledge-Based, Rule-Based, and Expert Systems; Core and Off-Core Processes in Systems Engineering; Digital Reconstruction Supporting Investigation of Mishaps; and Template Matching Approach to Signal Prediction.

Source record↗
NASA NTRS2005

Stroboscopic Interferometer for Measuring Mirror Vibrations

Stroboscopic interferometry is a technique for measuring the modes of vibration of mirrors that are lightweight and, therefore, unavoidably flexible. The technique was conceived especially for modal characterization of lightweight focusing mirror segments to be deployed in outer space; however, the technique can be applied to lightweight mirrors designed for use on Earth as well as the modal investigation of other optical and mechanical structures. To determine the modal structure of vibration of a mirror, it is necessary to excite the mirror by applying a force that varies periodically with time at a controllable frequency. The excitation can utilize sinusoidal, square, triangular, or even asynchronous waveforms. Because vibrational modes occur at specific resonant frequencies, it is necessary to perform synchronous measurements and sweep the frequency to locate the significant resonant modes. For a given mode it is possible to step the phase of data acquisition in order to capture the modal behavior over a single cycle of the resonant frequency. In order to measure interferometrically the vibrational response of the mirror at a given frequency, an interferometer must be suitably aligned with the mirror and adjustably phase-locked with the excitation signal. As in conventional stroboscopic photography, the basic idea in stroboscopic interferometry is to capture an image of the shape of a moving object (in this case, the vibrating mirror) at a specified instant of time in the vibration cycle. Adjusting the phase difference over a full cycle causes the interference fringes to vary over the full range of motion for the mode at the excitation frequency. The interference-fringe pattern is recorded as a function of the phase difference, and, from the resulting data, the surface shape of the mirror for the given mode is extracted. In addition to the interferometer and the mirror to be tested, the equipment needed for stroboscopic interferometry includes an arbitrary-function generator (that is, a signal generator), an oscilloscope, a trigger filter, and an advanced charge-coupled-device (CCD) camera. The optical components are positioned to form a pupil image of the mirror under test on the CCD chip, so that the interference pattern representative of the instantaneous mirror shape is imaged on the CCD chip.

Stahl, H. Philip↗
NASA NTRS2012

Evidence for Two Separate but Interlaced Components of the Chromospheric Magnetic Field

Chromospheric fibrils are generally thought to trace out horizontal magnetic fields that fan out from flux concentrations in the photosphere. A high-resolution (0.2") image taken in the core of the Ca IJ854.2 nm line shows the dark fibrils within an active region remnant as fine, loop-like features that are aligned parallel to each other and have lengths on the order of a supergranular diameter (approx.30 Mm). Comparison with a line-of-sight magnetogram confirms that the fibrils are centered above intranetwork areas, with one end rooted just inside the neighboring plage or strong unipolar network but the other endpoint less clearly defined. Focusing on a particular arcade-like structure lying entirely on one side of a filament channel (large-scale polarity inversion), we find that the total amount of positive-polarity flux underlying this "fibril arcade' is 50 times greater than the total amount of negative-polarity flux. Thus, if the fibrils represent closed loops, they must consist of very weak fields (in terms of flux density), which are interpenetrated by a more vertical field that contains most of the flux. This surprising result suggests that the fibrils in unipolar regions connect the network to the nearby intranetwork flux, while the bulk of the network flux is diverted upward into the corona and connects to remote regions of the opposite polarity. We conclude that the chromospheric field near the edge of the network has an interlaced structure resembling that in sunspot penumbrae, with the fibrils representing the low-lying horizontal flux that remains trapped within the highly nonpotential chromospheric layer.

Muglach, K.↗
NASA NTRS2012

Hubble Space Telescope Observations of the HD 202628 Debris Disk

A ring-shaped debris disk around the G2V star HD 202628 (d = 24.4 pc) was imaged in scattered light at visible wavelengths using the coronagraphic mode of the Space Telescope Imaging Spectrograph on the Hubble Space Telescope. The ring is inclined by approx.64deg from face-on, based on the apparent major/minor axis ratio, with the major axis aligned along PA = 130deg. It has inner and outer radii (> 50% maximum surface brightness) of 139 AU and 193 AU in the northwest ansae and 161 AU and 223 AU in the southeast ((Delta)r/r approx. = 0.4). The maximum visible radial extent is approx. 254 AU. With a mean surface brightnesses of V approx. = 24 mag arcsec.(sup -2), this is the faintest debris disk observed to date in reflected light. The center of the ring appears offset from the star by approx.28 AU (deprojected). An ellipse fit to the inner edge has an eccentricity of 0.18 and a = 158 AU. This offset, along with the relatively sharp inner edge of the ring, suggests the influence of a planetary-mass companion. There is a strong similarity with the debris ring around Fomalhaut, though HD 202628 is a more mature star with an estimated age of about 2 Gyr. We also provide surface brightness limits for nine other stars in our study with strong Spitzer excesses around which no debris disks were detected in scattered light (HD 377, HD 7590, HD 38858, HD 45184, HD 73350, HD 135599, HD 145229, HD 187897, and HD 201219).

Krist, John E.↗
DOE OSTI2013

Structural and Morphological Evolution of Lead Dendrites during Electrochemical Migration

The electrochemical deposition and dissolution of lead on gold electrodes immersed in an aqueous solution of lead nitrate were studied in situ using a biasing liquid cell by transmission electron microscopy (TEM). We investigate in real time the growth mechanisms of lead dendrites as deposited on the electrodes under an applied potential. TEM images reveal that lead dendrites are developed by the fast protrusion of lead branches in the electrolyte and tip splitting. And, the fast growing tip of the dendritic branch is composed of polycrystalline nanograins and it develops into a single crystalline branch eventually. This study demonstrated unique electrochemical growth of single crystal dendrites through nucleation, aggregation, alignment and attachment of randomly oriented small grains. Additionally, we found the lead concentration in the electrolyte drastically influences the morphology of dendritic formation.

25 ENERGY STORAGE↗
NASA NTRS2014

Aurora on Ganymede

Jupiter's largest satellite Ganymede is unique because it possesses an internal magnetic field strong enough to create a small magnetosphere around the satellite. The interaction between Ganymede's magentosphere and the Jovian magnetic field and magnetospheric plasma generates classic polar auroral emissions from Ganymede which have been captured in a series of stunning ultraviolet images using the Hubble Space Telescope on six different dates from 1998 to 2012. Analysis of these images (McGrath et al. 2013) has provided a nearly global mapping of the location of Ganymede's auroral ovals, which appear to be remarkably stable in the 14 years spanning the observations. The location of the auroral ovals is compared with several model predictions of the boundary between open and closed magnetic field lines (Koop and Ip 2002; Khurana et al. 2007; Jia et al. 2009), a region where strong field aligned potentials are a likely candidate to accelerate electrons that produce the auroral emissions. The location of the auroral emission is also compared with the polar cap boundary on Ganymede, thought to be produced by charged particle bombardment of the polar region, as delineated by color ratio images acquired by the Galileo mission (Khurana et al. 2007).

McGrath, Melissa A.↗
NASA NTRS2012

Wavefront Compensation Segmented Mirror Sensing and Control

The primary mirror of very large submillimeter-wave telescopes will necessarily be segmented into many separate mirror panels. These panels must be continuously co-phased to keep the telescope wavefront error less than a small fraction of a wavelength, to ten microns RMS (root mean square) or less. This performance must be maintained continuously across the full aperture of the telescope, in all pointing conditions, and in a variable thermal environment. A wavefront compensation segmented mirror sensing and control system, consisting of optical edge sensors, Wavefront Compensation Estimator/Controller Soft ware, and segment position actuators is proposed. Optical edge sensors are placed two per each segment-to-segment edge to continuously measure changes in segment state. Segment position actuators (three per segment) are used to move the panels. A computer control system uses the edge sensor measurements to estimate the state of all of the segments and to predict the wavefront error; segment actuator commands are computed that minimize the wavefront error. Translational or rotational motions of one segment relative to the other cause lateral displacement of the light beam, which is measured by the imaging sensor. For high accuracy, the collimator uses a shaped mask, such as one or more slits, so that the light beam forms a pattern on the sensor that permits sensing accuracy of better than 0.1 micron in two axes: in the z or local surface normal direction, and in the y direction parallel to the mirror surface and perpendicular to the beam direction. Using a co-aligned pair of sensors, with the location of the detector and collimated light source interchanged, four degrees of freedom can be sensed: transverse x and y displacements, as well as two bending angles (pitch and yaw). In this approach, each optical edge sensor head has a collimator and an imager, placing one sensor head on each side of a segment gap, with two parallel light beams crossing the gap. Two sets of optical edge sensors are used per segment-to-segment edge, separated by a finite distance along the segment edge, for four optical heads, each with an imager and a collimator. By orienting the beam direction of one edge sensor pair to be +45 away from the segment edge direction, and the other sensor pair to be oriented -45 away from the segment edge direction, all six degrees of freedom of relative motion between the segments can be measured with some redundancy. The software resides in a computer that receives each of the optical edge sensor signals, as well as telescope pointing commands. It feeds back the edge sensor signals to keep the primary mirror figure within specification. It uses a feed-forward control to compensate for global effects such as decollimation of the primary and secondary mirrors due to gravity sag as the telescope pointing changes to track science objects. Three segment position actuators will be provided per segment to enable controlled motions in the piston, tip, and tilt degrees of freedom. These actuators are driven by the software, providing the optical changes needed to keep the telescope phased.

Redding, David C.↗
DOE OSTI2014

DCE-MRI defined subvolumes of a brain metastatic lesion by principle component analysis and fuzzy-c-means clustering for response assessment of radiation therapy

Purpose: To develop a pharmacokinetic modelfree framework to analyze the dynamic contrast enhanced magnetic resonance imaging (DCE-MRI) data for assessment of response of brain metastases to radiation therapy. Methods: Twenty patients with 45 analyzable brain metastases had MRI scans prior to whole brain radiation therapy (WBRT) and at the end of the 2-week therapy. The volumetric DCE images covering the whole brain were acquired on a 3T scanner with approximately 5 s temporal resolution and a total scan time of about 3 min. DCE curves from all voxels of the 45 brain metastases were normalized and then temporally aligned. A DCE matrix that is constructed from the aligned DCE curves of all voxels of the 45 lesions obtained prior to WBRT is processed by principal component analysis to generate the principal components (PCs). Then, the projection coefficient maps prior to and at the end of WBRT are created for each lesion. Next, a pattern recognition technique, based upon fuzzy-c-means clustering, is used to delineate the tumor subvolumes relating to the value of the significant projection coefficients. The relationship between changes in different tumor subvolumes and treatment response was evaluated to differentiate responsive from stable and progressive tumors. Performance of the PC-defined tumor subvolume was also evaluated by receiver operating characteristic (ROC) analysis in prediction of nonresponsive lesions and compared with physiological-defined tumor subvolumes. Results: The projection coefficient maps of the first three PCs contain almost all response-related information in DCE curves of brain metastases. The first projection coefficient, related to the area under DCE curves, is the major component to determine response while the third one has a complimentary role. In ROC analysis, the area under curve of 0.88 ± 0.05 and 0.86 ± 0.06 were achieved for the PC-defined and physiological-defined tumor subvolume in response assessment. Conclusions: The PC-defined subvolume of a brain metastasis could predict tumor response to therapy similar to the physiological-defined one, while the former is determined more rapidly for clinical decision-making support.

62 RADIOLOGY AND NUCLEAR MEDICINE↗
NASA NTRS2016

Scheduling Observations of Celestial Objects for Earth Observing Sensor Calibration

Radiometric calibration of Earth-observing satellite sensors is critical for tracking on-orbit gain changes through- out the satellite's mission. The Moon, being a stable, well-characterized radiometric target, has been used effectively for tracking the relative gain changes of the reflective solar bands for the Moderate Resolution Imaging Spectroradiometer (MODIS) on board EOS AM-1 (Terra) and PM-1 (Aqua). The Moon is viewed through the MODIS space-view port, and the relative phase of the Moon is restricted to within 0.5 degrees of a chosen target phase to increase the accuracy of the calibration. These geometric restrictions require spacecraft maneuvers in order to bring space-view port into proper alignment with the position of the Moon when the phase requirement is met. In this paper, we describe a versatile tool for scheduling such maneuvers based on the required geometry and lunar phase restrictions for a general spacecraft bound instrument. The results of the scheduling tool have been verified using lunar images from Aqua and Terra MODIS after a scheduled roll maneuver was performed. This tool has also been tested for the Visible Infrared Imaging Radiometer Suite (VIIRS) and the Advanced Technology Microwave Sounder on-board the Suomi-NPP spacecraft. As an extension of this work, we have also developed a tool for scheduling views of bright stars. These stars provide another well-characterized radiometric source that can be used for sensor calibration. This tool has been implemented to determine the times in which a chosen star can be viewed by the high gain stages of the day/night band for the VIIRS instrument.

Wilson, Truman↗