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Similarity Analysis: Comparison of a Standard 60mL With a 50mL Container for MicroCT

A 50mL container with a one inch outer diameter has been proposed for holding specimen materials scanned at LLNL and Tyndall Air Force Research Laboratory (TAFRL). In order to determine whether or not this new container would significantly affect MicroCT results, a similarity analysis procedure developed at LLNL was used. This procedure compares multiple first and second order statistics obtained from CT reconstructed images generated by the MicroCT analysis process, and prescribes similarity constraints as guidance. For this study, water was scanned on the MicroCT system at LLNL, twice in the standard 60mL container and twice in the proposed 50mL container. Data were analyzed following the Standard Operating Procedure (SOP) for MicroCT analysis. Comparison of analytical results shows that the new container does not satisfy all similarity analysis criteria (certain second order statistics are outside of similarity analysis constraints).

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Similarity Analysis: Comparison of a Standard 60mL With an Anti-Static Container for MicroCT

Pursuant to safety concerns, an anti-static container has been proposed for holding specimen materials scanned by an International Partner (IP) on a MicroCT system. In order to determine whether or not this new container would significantly affect MicroCT results, a similarity analysis procedure developed at LLNL was used. This procedure compares multiple first and second order statistics obtained from CT reconstructed images generated by the MicroCT analysis process, and prescribes similarity constraints as guidance. For this study, water was scanned on a MicroCT system in both a standard container and the proposed anti-static container under Test Plan 83. Data were analyzed following the Standard Operating Procedure (SOP) for MicroCT analysis. Comparison of analytical results shows that the anti-static container satisfies all similarity analysis criteria.

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MAN-004 Design Standards Manual

At Sandia National Laboratories in New Mexico (SNL/NM), the design, construction, operation, and maintenance of facilities is guided by industry standards, a graded approach, and the systematic analysis of life cycle benefits received for costs incurred. The design of the physical plant must ensure that the facilities are "fit for use," and provide conditions that effectively, efficiently, and safely support current and future mission needs. In addition, SNL/NM applies sustainable design principles, using an integrated whole-building design approach, from site planning to facility design, construction, and operation to ensure building resource efficiency and the health and productivity of occupants. The safety and health of the workforce and the public, any possible effects on the environment, and compliance with building codes take precedence over project issues, such as performance, cost, and schedule. These design standards generally apply to all disciplines on all SNL/NM projects. Architectural and engineering design must be both functional and cost-effective. Facility design must be tailored to fit its intended function, while emphasizing low-maintenance, energy-efficient, and energy-conscious design. Design facilities that can be maintained easily, with readily accessible equipment areas, low maintenance, and quality systems. To promote an orderly and efficient appearance, architectural features of new facilities must complement and enhance the existing architecture at the site. As an Architectural and Engineering (A/E) professional, you must advise the Project Manager when this approach is prohibitively expensive. You are encouraged to use professional judgment and ingenuity to produce a coordinated interdisciplinary design that is cost-effective, easily contractible or buildable, high-performing, aesthetically pleasing, and compliant with applicable building codes. Close coordination and development of civil, landscape, structural, architectural, fire protection, mechanical, electrical, telecommunications, and security features is expected to ensure compatibility with planned functional equipment and to facilitate constructability. If portions of the design are subcontracted to specialists, delivery of the finished design documents must not be considered complete until the subcontracted portions are also submitted for review. You must, along with support consultants, perform functional analyses and programming in developing design solutions. These solutions must reflect coordination of the competing functional, budgetary, and physical requirements for the project. During design phases, meetings between you and the SNL/NM Project Team to discuss and resolve design issues are required. These meetings are a normal part of the design process. For specific design-review requirements, see the project-specific Design Criteria. In addition to the design requirements described in this manual, instructive information is provided to explain the sustainable building practice goals for design, construction, operation, and maintenance of SNL/NM facilities. Please notify SNL/NM personnel of design best practices not included in this manual, so they can be incorporated in future updates.

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Energy Efficiency Appliance Standards: Where do we stand, how far can we go and how do we get there? An analysis across several economies

This paper analyses several potential savings scenarios for minimum energy performance standard (MEPS) and comparable programs for governments participating i n the Super-efficient Equipment and Appliance Deployment (SEAD) Initiative, of the Clean Energy Ministerial, which represent over 60% of primary energy consumption in the world. We compare projected energy savings from the main end uses in the residential sector using three energy efficiency scenarios: (1) recent achievements, (2) cost-effective saving potential, and (3) energy efficiency technical potential. The recent achievement scenario (1) evaluates the future impact of MEPS enacted or under development between 2010 and 2012. The cost-effective potential scenario (2) identifies the maximum potential for energy efficiency that results in net benefits to the consumer. The best available technology scenario (3) re presents the full potential of energy efficiency considering best available technologies as candidates for MEPS and incentive programs. We use the Bottom Up Energy Analysis System (BUENAS), developed by Lawrence Berkeley National Laboratory in collaboration with the Collaborative Labelling and Appliances Standards Program (CLASP), to provide a consistent methodology to com pare the different scenarios. This paper focuses on the main end uses in the residential sector. The comparison of the three scenarios for each economy provides possible opportunities for scaling up current policies or implementing additional policies. This comparison across economies reveals country best practices as well as end uses that present the greatest additional potential savings. The paper describes areas where methodologies and additional policy instruments can increase penetration of energy efficient technologies. First , we summarize the barriers and provide remedial policy tools/best practices, such as techno-economic analysis, in response to each barriers that prevent economies from capturing the full cost-effective potentials of MEPS (Scenario 1 to 2). Then, we consider the possible complementary policy options, such as incentive pro grams, to reach the full technical potential of energy efficiency in the residential sector (Scenario 2 to 3).

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Design of Standards and Labeling programs in Chile: Techno-Economic Analysis for Refrigerators

Lawrence Berkeley National Laboratory is a global leader in the study of energy efficiency and its effective implementation through government policy. The Energy Analysis and Environmental Impacts Department of LBNL’s Environmental Energy Technologies Division provides technical assistance to help federal, stat e and local government agencies in the United States, and throughout the world, develop long-term strategies, policy, and programs to encourage energy efficiency in all sectors and industries. In the past, LBNL has assisted staff of various countries government agencies and their con tractors in providing methodologies to analyze cost-effectiveness of regulations and asses s overall national impacts of efficiency programs. The paper presents the work done in collaboration with the Ministry of Energy (MoE) in Chile and the Collaborative Labeling Appliance Standards Programs (CLASP) on designing a Minimum Energy Performance Standards (MEPS) and ext ending the current labeling program for refrigerators.

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End-Use Opportunity Analysis from Progress Indicator Results for ASHRAE Standard 90.1-2013

This report and an accompanying spreadsheet (PNNL 2014a) compile the end use building simulation results for prototype buildings throughout the United States. The results represent he energy use of each edition of ASHRAE Standard 90.1, Energy Standard for Buildings Except Low-Rise Residential Buildings (ASHRAE 2004, 2007, 2010, 2013). PNNL examined the simulation results to determine how the remaining energy was used.

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Performance Specification for Standardized Transportation, Aging, and Disposal Canister Systems (Rev.2)

This performance specification document addresses use of a standardized transportation, aging, and disposal (STAD) canister system in the spent nuclear fuel (SNF) waste management system. This document was developed to support STAD canister system studies and potential research, development, and demonstration activities. Requirements in this specification may evolve with time based on results from analyses, experiments, design studies, system evaluations and demonstrations, as well as other factors. A STAD canister system consists of a canister, together with a storage or aging overpack/module/vault, a shielded transfer cask (STC), a site transporter, a transportation overpack, and a transportation skid. Three sizes of circular cross section STAD canister variants are specified in this document. The small STAD canister capacity is four pressurized water reactor (PWR) or nine boiling water reactor (BWR) SNF assemblies. The medium STAD canister capacity is 12 PWR or 32 BWR SNF assemblies. The large STAD canister capacity is 21 PWR or 44 BWR SNF assemblies. Using standardized canisters for SNF facilitates the interface between storage at an independent spent fuel storage installation (ISFSI) or a DOEowned interim storage facility (ISF), transportation between facilities, and disposal at a repository. Multiple STAD canisters may be stored in a single storage overpack and/or a single transportation overpack. The US Nuclear Regulatory Commission (NRC) requirements currently used for storage and transportation are adopted for the STAD canister system. Approved approaches (guidance) in NRC storage and transportation documents are also adopted as requirements for the STAD canister system to facilitate obtaining NRC Certificates of Compliance (CoCs) for STAD canister systems. Performance specifications in this document are also informed by STAD canister disposability in various geologic media and consideration of ISF (and geologic repository) handling facility design, operations, and licensing requirements.

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Rationale for the Performance Specification for Standardized Transportation, Aging, and Disposal Canister Systems (Rev.1)

This document provides the rationale for the specifications for the standardized transportation, aging, and disposal (STAD) canister systems provided in Performance Specification for Standardized Transportation, Aging, and Disposal Canister Systems, FCRD-NFST-2014-000579, Rev. 2, referred to as STAD Spec herein. The STAD Spec was developed to support STAD canister system studies and potential research, development, and demonstration activities. Requirements in the specification may evolve with time based on results from analyses, experiments, design studies, system evaluations and demonstrations, as well as other factors. The STAD canister system consists of a canister, together with a storage or aging overpack/module/vault, a shielded transfer cask (STC), a site transporter, a transportation overpack, and a transportation skid. Three sizes of circular cross section STAD canister variants are specified. The small STAD canister capacity is four pressurized water reactor (PWR) or nine boiling water reactor (BWR) spent nuclear fuel (SNF) assemblies. The medium STAD canister capacity is 12 PWR or 32 BWR SNF assemblies. The large STAD canister capacity is 21 PWR or 44 BWR SNF assemblies. There are 60 specifications in the STAD Spec that cover the STAD canister general design attributes, canister safety functional requirements, operational considerations, materials, storage and aging system requirements, and transportation system requirements. The 60 specifications are derived from regulatory requirements, regulatory guidance, STAD canister disposability considerations, and interim storage facility (ISF) and geologic repository handling facility considerations.

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R&D for Safety Codes and Standards: Materials and Components Compatibility

This project addresses the following technical barriers from the Safety, Codes and Standards section of the 2012 Fuel Cell Technologies Office Multi-Year Research, Development and Demonstration Plan (section 3.8): (A) Safety data and information: limited access and availability (F) Enabling national and international markets requires consistent RCS (G) Insufficient technical data to revise standards.

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Community-Wide Zero Energy Ready Home Standard

This report outlines the steps a developer can take when creating and implementing high performance standards such as the U.S. Department of Energy’s (DOE’s) Zero Energy Ready Home (ZERH) standards on a community-wide scale. The report also describes the specific examples of how this process is underway in the Stapleton community in Denver, Colorado, by the developer Forest City.

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Search for the Higgs Boson and Rare Standard Model Processes in the E T +B-Jets Signature at the Collider Detector at Fermilab

We study rare processes of the standard model of particle physics (SM) in events with missing transverse energy E T , no leptons, and two or three jets, of which at least one is identified as originating from a $b$-quark (E T +b-jets signature). We present a search for the SM Higgs boson produced in association with a $W$ or $Z$ boson when the Higgs decays into \bbbar. We consider the scenario where $Z \to \nu \nu$, or $W \to l \nu$ and the lepton escapes detection. This dissertation analyzes $7.8~\mbox{fb$^{-1}$}$ of data collected by the CDF~II experiment at Fermilab. For the first time, we analyze events with \emph{relaxed kinematic} requirements, yielding an increase of 30- 40\% in acceptance to the $WH/ZH$ signal. We collect events from three different triggers and parametrize the efficiency of their logical combination (OR) using a novel artificial neural network ($NN$) technique. To increase the sensitivity to the signal, we implement a $NN$ to remove the huge instrumental background. An additional $NN$ is used to discriminate the Higgs signal from the remaining background. We check our background modeling by comparing data against backgrounds in many control regions, and find good agreement. Observing no significant excess in the data, we place 95\% confidence level (C.L.) upper limits on the Higgs boson production cross section. For a mass of $115~\mbox{GeV/$c^2$}$ the expected (observed) limit is $2.9$ ($2.3$) times the standard model prediction. Compared to the last iteration of this analysis, this result improves the significance by 10\% throughout the $100-150~\mbox{GeV/$c^2$}$ mass range. This is one of the most sensitive at the Tevatron in this mass range. We cross-check the tools developed in this dissertation by measuring the cross-section of top pair, electroweak single top and diboson ($WZ+ZZ$) production.

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Search for Physics Beyond the Standard Model in the Trilepton Signature in $\bar{p}-p$ collisions at $\sqrt{s} = 1.96$~TeV with CDF II

The standard model (SM) of particles and fields is a theory that has proven very accurate in the currently accessible collider energies. Nonetheless, the SM is theoretically incomplete in the sense that it leaves many questions and problems unanswered, for example, the origin of electroweak symmetry breaking (EWSB). The Higgs boson is introduced to the SM to provide a mechanism for electroweak symmetry breaking and masses to quarks and leptons. However, the introduction of the Higgs mechanism has the undesirable effect of introducing the hierarchy problem which is characterized by quadratically divergent contributions to the Higgs mass squared. Supersymmetry (SUSY) has been postulated as a way to solve the problem of the fine tuning of the Higgs self-interactions, and additionally to provide a possible mechanism for EWSB. The golden search channel for mSUGRA is the $\chi{^\pm}_{1} \chi^{0}_{2} \rightarrow 3\ell$ (three leptons) channel. It offers a reasonable signal $\sigma \ x BR$ with very small contributions from Standard Model backgrounds. This thesis, presents a search for chargino-neutralino production within the mSUGRA framework.

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Search for the Standard Model Higgs Boson in the Diphoton Final State in $p\bar{p}$ Collisions at $\sqrt{s}$ = 1.96 TeV Using the CDF II Detector

We present a search for the Standard Model Higgs boson decaying into a pair of photons produced in p$p\bar{p}$ collisions with a center of mass energy of 1.96 TeV. The results are based on data corresponding to an integrated luminosity of 10 fb -1 collected by the CDF II detector. Higgs boson candidate events are identified by reconstructing two photons in either the central or plug regions of the detector. The acceptance for identifying photons is significantly increased by using a new algorithm designed to reconstruct photons in the central region that have converted to an electron-positron pair. In addition, a new neural network discriminant is employed to improve the identification of non-converting central photons. No evidence for the Higgs boson is observed in the data, and we set an upper limit on the cross section for Higgs boson production multiplied by the H → γγ branching ratio. For a Higgs boson mass of 125 GeV/c 2 , we obtain an observed (expected) limit of 12.2 (10.8) times the Standard Model prediction at the 95% credibility level.

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Integrated Data Collection Analysis (IDCA) Program - Statistical Analysis of RDX Standard Data Sets

The Integrated Data Collection Analysis (IDCA) program is conducting a Proficiency Test for Small- Scale Safety and Thermal (SSST) testing of homemade explosives (HMEs). Described here are statistical analyses of the results for impact, friction, electrostatic discharge, and differential scanning calorimetry analysis of the RDX Type II Class 5 standard. The material was tested as a well-characterized standard several times during the proficiency study to assess differences among participants and the range of results that may arise for well-behaved explosive materials. The analyses show that there are detectable differences among the results from IDCA participants. While these differences are statistically significant, most of them can be disregarded for comparison purposes to assess potential variability when laboratories attempt to measure identical samples using methods assumed to be nominally the same. The results presented in this report include the average sensitivity results for the IDCA participants and the ranges of values obtained. The ranges represent variation about the mean values of the tests of between 26% and 42%. The magnitude of this variation is attributed to differences in operator, method, and environment as well as the use of different instruments that are also of varying age. The results appear to be a good representation of the broader safety testing community based on the range of methods, instruments, and environments included in the IDCA Proficiency Test.

round-robin test↗

Integrated Data Collection Analysis (IDCA) Program — RDX Standard Data Sets

The Integrated Data Collection Analysis (IDCA) program is conducting a proficiency study for Small- Scale Safety and Thermal (SSST) testing of homemade explosives (HMEs). Described here are the results for impact, friction, electrostatic discharge, and differential scanning calorimetry analysis of the RDX Type II Class 5 standard, for a third and fourth time in the Proficiency Test and averaged with the analysis results from the first and second time. The results, from averaging all four sets (1, 2, 3 and 4) of data suggest a material to have slightly more impact sensitivity, more BAM friction sensitivity, less ABL friction sensitivity, similar ESD sensitivity, and same DSC sensitivity, compared to the results from Set 1, which was used previously as the values for the RDX standard in IDCA Analysis Reports.

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Synthesis of SHAL and SHAL Precursor Standard, CRADA No. TC02174.0

The purpose of this CRADA was to establish a collaborative effort between SHAL Technologies and Lawrence Livermore National Laboratory that would advance the development and testing of a family of small molecule oncology drugs and companion diagnostics called selective high affinity ligands (SHALs) for the treatment of advanced non-Hodgkin’s lymphoma. These compounds were first synthesized by the LLNL chemist participating in this CRADA when the compounds were first developed (2004-2008) by the founders of SHAL Technologies (while they were employed at LLNL). This CRADA initially had five deliverables. Deliverables 1-3 involved LLNL’s synthesis of 10-50 mg of the SHALs SH7133 and SH7139 using the same bench-scale conditions used previously, their purification, and obtaining data needed to demonstrate the mass and purity of the compounds. Deliverable 4, which was to be completed by SHAL Technologies, was the comparison of the bench-scale synthetic products to the same compounds manufactured on the multigram to kilogram scale by the contract research organization (CRO) AmbioPharm Inc. The fifth deliverable was this final report. An amendment was made to add the additional tasks and deliverables needed to synthesize the third SHAL standard SH7129 (the diagnostic) and compare it to product manufactured by AmbioPharm. During the testing of the three standards synthesized by LLNL, the SHAL compounds were found to lack biological activity. When we discovered that a commercial chemical supplier provided both LLNL and our CRO AmbioPharm with a SHAL precursor that had the wrong structure, two amendments to the CRADA were made to add additional tasks and deliverables to enable us to repeat all the syntheses and conduct more extensive testing of the bench scale and manufactured products. Once the final correct products were synthesized and confirmed to have the right structures, a third amendment was added to the CRADA to enable the synthesis of two fragments of the SHALs to determine if these compounds are produced when the SHALs are metabolized. This last synthesis was included to provide the information needed to establish a second, new CRADA between SHAL Technologies and LLNL that would focus on the identifying how the SHALs are metabolized and how their metabolic products may be responsible for the selective killing of tumor cells over-expressing the protein targeted by the SHALs, HLA-DR10.

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Searching for Physics Beyond the Standard Model: Strongly-Coupled Field Theories at the Intensity and Energy Frontiers

This proposal is to develop the software and algorithmic infrastructure needed for the numerical study of quantum chromodynamics (QCD), and of theories that have been proposed to describe physics beyond the Standard Model (BSM) of high energy physics, on current and future computers. This infrastructure will enable users (1) to improve the accuracy of QCD calculations to the point where they no longer limit what can be learned from high-precision experiments that seek to test the Standard Model, and (2) to determine the predictions of BSM theories in order to understand which of them are consistent with the data that will soon be available from the LHC. Work will include the extension and optimizations of community codes for the next generation of leadership class computers, the IBM Blue Gene/Q and the Cray XE/XK, and for the dedicated hardware funded for our field by the Department of Energy. Members of our collaboration at Brookhaven National Laboratory and Columbia University worked on the design of the Blue Gene/Q, and have begun to develop software for it. Under this grant we will build upon their experience to produce high-efficiency production codes for this machine. Cray XE/XK computers with many thousands of GPU accelerators will soon be available, and the dedicated commodity clusters we obtain with DOE funding include growing numbers of GPUs. We will work with our partners in NVIDIA's Emerging Technology group to scale our existing software to thousands of GPUs, and to produce highly efficient production codes for these machines. Work under this grant will also include the development of new algorithms for the effective use of heterogeneous computers, and their integration into our codes. It will include improvements of Krylov solvers and the development of new multigrid methods in collaboration with members of the FASTMath SciDAC Institute, using their HYPRE framework, as well as work on improved symplectic integrators.

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Thermodynamic Properties of Aqueous Carbonate Species and Solid Carbonate Phases of Selected Trace Elements pertinent to Drinking Water Standards of the U.S. Environmental Protection Agency

This report contains a series of tables summarizing the thermodynamic properties of aqueous carbonate complexes and solid carbonate phases of the following elements: arsenic (As), barium (Ba), cadmium (Cd), chromium (Cr), cobalt (Co), copper (Cu), iron (Fe), lead (Pb), manganese (Mn), mercury (Hg), nickel (Ni) thallium (Tl), uranium (U) and zinc (Zn). Most of these elements are potentially hazardous as defined by extant primary drinking water standards of the United States Environmental Protection Agency (EPA). The remainder are not considered hazardous, but are either listed by EPA under secondary standards, or because they can adversely affect drinking water quality. Additional tables are included giving the thermodynamic properties for carbonates of the alkali metal and alkali earth elements, sodium (Na), potassium (K), magnesium (Mg), calcium (Ca), and strontium (Sr), because of their value in developing correlative models to estimate the thermodynamic properties of carbonate minerals for which no such data currently exist. The purpose in creating the tables in this report is to provide future investigators with a convenient source for selecting and tracing the sources of thermodynamic data of the above listed elements for use in modeling their geochemical behavior in “underground sources of drinking water” (USDW). The incentive for doing so lies with a heightened concern over the potential consequences of the proposed capture and storage of carbon dioxide (CO2) generated by fossil fuel fired power plants in deep subsurface reservoirs. If CO2 were to leak from such reservoirs, it could migrate upward and contaminate USDWs with undesirable, but undetermined, consequences to water quality. The EPA, Office of Research and Development, through an Interagency Agreement with the U.S. Department of Energy at the Lawrence Berkeley National Laboratory, funded the preparation of this report.

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