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At least 1,081 records · Page 60

A New Configuration of Paralleled Modular ANPC Multilevel Converter Controlled by an Improved Modulation Method for 1 MHz, 1 MW EV Charger

In this work, a new configuration of the modular multilevel converter (MLC) based on the parallel connection of three-level active-neutral-point-clamped (3L-ANPC) cells as well as its improved modulation method is proposed for 1 MHz, 1 MW electric vehicle (EV) megacharger. In the proposed paralleled modular ANPC-MLC, only six high-frequency silicon carbide (SiC) power switches operating at 333 kHz are required to generate 1 MHz switching frequency spectrum. Moreover, the operating voltage of all power devices is halved, the magnitude of the first switching frequency harmonic cluster is decreased by the factor of five, and the load current is equally distributed between the 3L-ANPC legs by employing the proposed improved modulation method. Hence, the modularity, efficiency, and power density of the proposed converter are notably increased, whereas the value of passive components and the overall switching loss are remarkably decreased. In addition, an optimized design of the one 3L-ANPC cell of the proposed paralleled modular ANPC-MLC for 1 MHz, 1MW EV megacharger using Ansys SIwave, Icepak, and Q3D finite element method platforms is presented and analyzed in detail. The provided experimental results of the down-scaled setup verify the feasibility and viability of the proposed configuration as well as its improved switching pattern.

42 ENGINEERING↗

Model predictive direct power control for active power decoupled single-phase quasi- Z -source inverter

In this study, the active power filter (APF) that consists of a half-bridge leg and an ac capacitor is integrated in the single-phase quasi-Z-source inverter (qZSI) in this paper to avoid the second harmonic power flowing into the dc side. The capacitor of APF buffers the second harmonic power of the load, and the ac capacitor allows highly pulsating ac voltage, so that the capacitances of both dc and ac sides can be small. A model predictive direct power control (DPC) is further proposed to achieve the purpose of this newtopology through predicting the capacitor voltage of APF at each sampling period and ensuring the APF power to track the second harmonic power of single-phase qZSI. Simulation and experimental results verify the model predictive DPC for the APF-integrated single-phase qZSI.

30 DIRECT ENERGY CONVERSION↗

A High Temperature Silicon Carbide mosfet Power Module With Integrated Silicon-On-Insulator-Based Gate Drive

Here we present a board-level integrated silicon carbide (SiC) MOSFET power module for high temperature and high power density application. Specifically, a silicon-on-insulator (SOI)-based gate driver capable of operating at 200°C ambient temperature is designed and fabricated. The sourcing and sinking current capability of the gate driver are tested under various ambient temperatures. Also, a 1200 V/100 A SiC MOSFET phase-leg power module is developed utilizing high temperature packaging technologies. The static characteristics, switching performance, and short-circuit behavior of the fabricated power module are fully evaluated at different temperatures. Moreover, a buck converter prototype composed of the SOI gate driver and SiC power module is built for high temperature continuous operation. The converter is operated at different switching frequencies up to 100 kHz, with its junction temperature monitored by a thermosensitive electrical parameter and compared with thermal simulation results. The experimental results from the continuous operation demonstrate the high temperature capability of the power module at a junction temperature greater than 225°C.

36 MATERIALS SCIENCE↗

Short-Circuit Characterization and Protection of 10-kV SiC mosfet

This paper presents the characterization of the temperature-dependent short-circuit performance of a Gen3 10 kV/20 A silicon carbide (SiC) mosfet. The test platform consisting of a phase-leg configuration and a fast speed 10-kV solid state circuit breaker, with temperature control, is introduced in detail. A novel FPGA-based short-circuit protection circuit having a response time of 1.5 μs is proposed and integrated into the gate driver. The short-circuit protection is validated through the platform. The short-circuit characteristics for both the hard switching fault and fault under load (FUL) types at various dc-link voltages (from 500 V to 6 kV) are tested and discussed. The saturation current increases with dc-link voltage and achieves 360 A at 6 kV. Different from low voltage SiC devices, there is no current spike in FUL type of fault. The temperature-dependent short-circuit performance is also presented from 25 to 125 °C. The difference of short-circuit waveforms at various initial junction temperatures can be neglected. Here, a thermal model of the 10-kV SiC mosfet is built for the junction temperature estimation during the short circuit and for analysis of the initial junction temperature impact on the short-circuit performance.

10-kV SiC mosfet↗

The Impact of Inverter Dead-Time in Single-Phase Wireless Power Transfer Systems

In this paper, the effect of the dead-time on a single-phase wireless power transfer system is studied in detail. In practice, the dead-time is always placed between the complementary switching pulses of the inverter phase-leg. At higher operating frequencies, the dead-time issues in the resonant inverter become critical, especially as the power level increases. The detailed analysis of the dead-time on a wireless power transfer system is discussed for different operating conditions of the inverter duty-cycle and power factor. The switching characteristics of the wireless power transfer system inverter are analyzed, and the notch phenomenon that appears at the output of the inverter is also discussed. A notch equation based on the observations is derived to predict the notch occurrence during the system operation. Furthermore, the mathematical expressions are presented for different notch conditions. Subsequently, the effect of the notches on the sensitivity and the power transfer of the series-series compensated wireless power transfer system is analyzed. Finally, the approach is verified experimentally on an 8 kW wireless power transfer system prototype, and the results are compared with the theoretical analysis.

42 ENGINEERING↗

Active Recycling Control Through Lithium Injection in EAST

The coating of tokamak walls with thin layers of lithium has been demonstrated to reduce plasma recycling from the plasma-facing surfaces and to improve overall plasma performance. These effects, including reduced divertor D α emission, the elimination of edge-localized modes, and increased energy confinement have been observed in multiple experiments when lithium coatings are applied before plasma discharges. However, this coating technology does not extrapolate to future long-pulse devices, since the lithium coatings will be passivated by the continual plasma flux onto the surface. In order to provide active conditioning capability, a new technology has been developed that is capable of injecting lithium powder into the scrape-off layer plasma during plasma discharges, where it quickly liquefies and turns into an aerosol. The use of this “lithium dropper” is under study at the Experimental Advanced Superconducting Tokamak (EAST), where the potential benefits of real-time wall conditioning via lithium injection are being tested. Here, we present an analysis of the recycling characteristics during EAST experiments testing active lithium injection in order to assess recycling reduction and control. Lithium aerosol was injected from the top of the machine, with one system dropping lithium near the X-point and another into the low-field side divertor leg. The injection of lithium into the SOL reduced divertor recycling, as evidenced by reduced D α emission with ion flux measured by probes relatively unchanged. This effect is strongest in the active divertor, confirming the lithium is transported to strongly plasma-wetted areas. Furthermore, quantitative analysis of the recycling changes using the SOLPS edge plasma and neutral transport code indicated a ~20% reduction in recycling coefficient with lithium injection.

70 PLASMA PHYSICS AND FUSION TECHNOLOGY↗

Comparative Investigation of Current-Source Inverters using SiC Discrete Devices and Power Modules

The purpose of this paper is to investigate the impact of the SiC device packages on the commutation performance characteristics of current-source inverters (CSIs). The parasitic components in the CSI current commutation loop between the two-phase legs and output capacitors have a significant impact on the high-frequency performance of the SiC devices. To meet the elevated current requirements of high-power CSIs, it is often necessary to connect multiple discrete devices in parallel which increases the current commutation loop length. The selection of compact high-power SiC MOSFET and Schottky diode modules instead of discrete devices can be highly desirable to reduce the loop inductance and improve the system performance and power density. Two CSI benchtop prototype units, one with SiC discrete devices and the other with power modules, have been designed and tested, and the performances of the two CSIs are compared. The CSI with SiC power modules significantly reduces the inverter volume and lowers the parasitic inductance by 60% and the voltage ripple amplitude by 20% compared to the CSI unit with discrete devices.

42 ENGINEERING↗

Phase Shift Control of a Three-Phase Inverter for Balanced Secondary Currents in Misaligned Three-Phase Inductive Power Transfer Systems

This paper presents a strategy for generating fundamental reference voltage commands for a double-sided LCC tuned three-phase wireless power transfer (WPT) system to achieve balanced output currents when the receiver and transmitter are not perfectly aligned. Formulas for translating the normalized fundamental current commands into phase-shift commands for two of the phase legs in a two-level three-phase inverter are derived. The methodology is validated through circuit simulations performed using coupler models derived from finite-element simulations. Simulation results for a 1.5 k W system design are included, which indicate near perfect correction of imbalance in the secondary currents for a typical misalignment case.

Pries, Jason↗

PlanHab * : hypoxia does not worsen the impairment of skeletal muscle oxidative function induced by bed rest alone

Key points Superposition of hypoxia on 21 day bed rest did not worsen the impairment of skeletal muscle oxidative function induced by bed rest alone. A significant impairment of maximal oxidative performance was identified downstream of cardiovascular O 2 delivery, involving both the intramuscular matching between O 2 supply and utilization and mitochondrial respiration. These chronic adaptations appear to be relevant in terms of exposure to spaceflights and reduced gravity habitats (Moon or Mars), as characterized by low gravity and hypoxia, in patients with chronic diseases characterized by hypomobility/immobility and hypoxia, as well as in ageing. Abstract Skeletal muscle oxidative function was evaluated in 11 healthy males (mean ± SD age 27 ± 5 years) prior to (baseline data collection, BDC) and following a 21 day horizontal bed rest (BR), carried out in normoxia ( = 133 mmHg; N‐BR) and hypoxia ( = 90 mmHg; H‐BR). H‐BR was aimed at simulating reduced gravity habitats. The effects of a 21 day hypoxic ambulatory confinement ( = 90 mmHg; H‐AMB) were also assessed. Pulmonary O 2 uptake ( ), vastus lateralis fractional O 2 extraction (changes in deoxygenated haemoglobin + myoglobin concentration, Δ[deoxy(Hb + Mb)]; near‐infrared spectroscopy) and femoral artery blood flow (ultrasound Doppler) were evaluated during incremental one‐leg knee‐extension exercise (reduced constraints to cardiovascular O 2 delivery) carried out to voluntary exhaustion in a normoxic environment. Mitochondrial respiration was evaluated ex vivo by high‐resolution respirometry in permeabilized vastus lateralis fibres. decreased ( P < 0.05) after N‐BR (0.98 ± 0.13 L min −1 ) and H‐BR (0.96 ± 0.17 L min −1 ) vs . BDC (1.05 ± 0.14 L min −1 ). In the presence of a decreased (by ∼6–8%) thigh muscle volume, normalized per unit of muscle mass was not affected by both interventions. Δ[deoxy(Hb + Mb)] peak decreased ( P < 0.05) after N‐BR (65 ± 13% of limb ischaemia) and H‐BR (62 ± 12%) vs . BDC (73 ± 13%). H‐AMB did not alter or Δ[deoxy(Hb + Mb)] peak . An overshoot of Δ[deoxy(Hb + Mb)] was evident during the first minute of unloaded exercise after N‐BR and H‐BR. Arterial blood flow to the lower limb during both unloaded and peak knee extension was not affected by any intervention. Maximal ADP‐stimulated mitochondrial respiration decreased ( P < 0.05) after all interventions vs . control. In 21 day N‐BR, a significant impairment of oxidative metabolism occurred downstream of cardiovascular O 2 delivery, affecting both mitochondrial respiration and presumably the intramuscular matching between O 2 supply and utilization. Superposition of H on BR did not worsen the impairment induced by BR alone.

Salvadego, Desy↗

Numerical Model of Thermoelectric Topping Cycle of Coal-Fired Power Plant

Traditional fossil fuel power generation process typically has low efficiency. Large amount of the energy loss in Rankine cycle steam turbines (ST) is due to the temperature difference between the combustion flame temperature ~2250 K (adiabatic) and the high pressure steam temperature up to 900 K. However, some of this energy can be harvested using solid-state thermoelectric (TE) power generators which are placed into the gap between the flame temperature and the steam temperature that produce additional electrical power. This study investigates the potential placement of TE on water tube wall inside a boiler at a coal-fired power plant. Three-dimensional (3D) numerical model of a simplified TE module is developed, and hot gas temperature and steam temperature from the boiler are used as boundary conditions at the hot side and cold side of the TE. The numerical results are compared with analytical calculations. The 3D effects of the thermal spreading in the TE module are investigated. Parameters such as TE leg cross section area and TE fill factor are examined in order to maximize the electrical power production of the TE without sacrificing the boiler efficiency (i.e., reducing the steam temperature). The study also looks into the various locations inside the boiler that have good potential for TE installation.

32 ENERGY CONSERVATION, CONSUMPTION, AND UTILIZATI↗

System Design of a 2.0 MWth Sodium/Molten Salt Pilot System

Nitrate molten salt concentrating solar power (CSP) systems are currently deployed globally and are considered state-of the art heat transfer fluids (HTFs) for present day high-temperature operation. Although slightly higher limits may be possible with molten salt, to fully realize SunShot efficiency goals of $15/kWhth HTFs and an LCOE of 6¢/kWh, HTF technologies working at higher temperatures (e.g., 650 °C to 750 °C) will require an alternative to molten salts, such as with alkali metal systems. This investigation explores the development of a 2.0 MWth sodium receiver system that employs a sodium receiver as the HTF, as well as with a ternary chloride (20%NaCl/40%MgCl/40%KCl by mol wt.%) salt as a thermal energy storage (TES) medium to facilitate a 6-hr. storage duration. A sodium-to-salt heat exchanger model as well as a salt-to-sCO2 primary heat exchanger model are employed and evaluated in this investigation. A thermodynamic system design model was developed using Engineering Equation Solver (EES) where state properties were calculated at inlets and outlets along both hot and cold legs of the pilot-scale plant. This investigation assesses receiver performance as well as system efficiency studies for the pump and system operational ranges. Results found that high efficiency sodium receivers were found to have higher heat transfer coefficients and required far less spreading of incident flux. The system performance model results suggest that for a pump speed of 2400 RPM, respective hot and cold pump TDH values were determined to be 260.1–307 ft. and 260.1–307 ft for pump flow rates of 90–120 GPM.

41 EE - Solar Energy Technologies Office (EE-4S)↗

Summary of Conclusions and Recommendations Drawn from the DeepCWind Scaled Floating Offshore Wind System Test Campaign: Preprint

The DeepCwind consortium is a group of universities, national labs, and companies funded under a research initiative by the U.S. Department of Energy (DOE) to support the research and development of floating offshore wind power. The two main objectives of the project are to better understand the complex dynamic behavior of floating offshore wind systems and to create experimental data for use in validating the tools used in modeling these systems. In support of these objectives, the DeepCwind consortium conducted a model test campaign in 2011 of three generic floating wind systems, a tension-leg platform (TLP), a spar-buoy (spar), and a semisubmersible (semi). Each of the three platforms was designed to support a 1/50th-scale model of a 5 MW wind turbine and was tested under a variety of wind/wave conditions. The focus of this paper is to summarize the work done by consortium members in analyzing the data obtained from the test campaign and its use for validating the offshore wind modeling tool, FAST.

17 WIND ENERGY↗

An Investigation of Passive and Semi-Active TMD for a TLP Floating Offshore Wind Turbine in ULS Conditions

Floating offshore wind turbines are able to access deeper waters with stronger winds, but also have more complicated dynamic behavior than fixed-bottom offshore turbines, potentially resulting in larger loads. Structural control using tuned mass dampers (TMD) is a promising method for mitigating these loads. Previous research on structural control in wind turbines has typically considered passive devices and operational conditions. In this study, the effects of a passive tuned mass damper and a semi-active tuned mass damper, located at the tower top, are analyzed and simulated for the GE Haliade 150-6MW wind turbine located on the Glosten Pelastar tension-leg platform (TLP).

offshore wind turbines, dampers, tuned mass, semi-↗

1:52 Scale Testing of the First US Commercial Scale Floating Wind Turbine, VolturnUS: Testing Overview and the Evolution of Scale Model Testing Methods

Over the past 6 years, the University of Maine (UMaine) has been an active contributor in research and scale-model testing of floating offshore wind turbines (FOWTs). This paper serves to share the evolution of UMaine’s scale-model testing pedigree by exploring the various test campaigns at a high level, culminating with the design validation of the VolturnUS floating platform. These model test campaigns have each provided key insights into the behavior of FOWT platforms as well as improving the ability to perform model tests of FOWTs. In 2011, the UMaine-led DeepCwind Consortium carried out 1/50-scale model tests of a generic tension leg platform (TLP), a semi-submersible (semi), and a spar-buoy (spar) floating platform at the Maritime Research Institute Netherlands (MARIN) test facility. The designs were Froude-scaled and supported a scaled version of the 5-MW National Renewable Energy Laboratory (NREL) offshore research turbine. Data from these tests has been used extensively for numerical simulation validation efforts using NREL’s computer-aided engineering software FAST and laid the foundation for UMaine’s design efforts on VolturnUS. In 2013, UMaine conducted another test campaign at MARIN using the original semi-submersible from 2011 with an improved turbine as well as a 1:50-scale model of the VolturnUS concrete semi-submersible design. The improved DeepCwind semi-submersible data is currently being utilized in the validation of a large number of other analysis codes as part of the International Energy Agency’s OC5 project. In 2015, UMaine opened its own Wind/Wave test facility, the Alfond Wind/Wave Ocean Engineering Laboratory (W2). Utilizing this new facility, UMaine tested the 1:50-scale model DeepCwind semi-submersible, repeating the tests from MARIN, to validate the experimental equipment and procedures as well as demonstrate the capability of the W2. In 2016 UMaine carried out testing of a 1:52-scale model of the 100% design of the VolturnUS with a 6-MW topside as a final design validation to support the US Department of Energy-supported, full-scale Aqua Ventus demonstration project scheduled to be connected to the grid in 2019. A newly designed 6-MW scale model turbine was used in this test and the performance-matched turbine design methodology is described. Selected results from the test campaign and preliminary numerical comparisons are discussed as well as key lessons learned from the model test campaigns are presented.

17 WIND ENERGY↗

Machine learning-driven design and self-sensing capabilities of automotive bumper lattices for adaptive impact response

We present a novel approach to design an automotive bumper energy absorber using carbon fiber reinforced polymer composites, optimized to meet conflicting performance requirements for two distinct impact scenarios. The design must satisfy both a low-speed (2.5 mph) pendulum intrusion test, simulating vehicle-to-vehicle collisions, and a high-speed (25 mph) leg flexion test, replicating pedestrian impacts. These tests demand opposing deformation characteristics: high flexibility (deformation < 85 mm) for the former and high stiffness (deformation < 22 mm) for the latter. To address these contradictory requirements, we developed a machine learning (ML) framework for inverse optimization of lattice designs and material selection. Unlike traditional iterative design processes, our ML model directly outputs optimal design parameters and material choices based on target performance inputs. The energy absorber was fabricated using advanced additive manufacturing techniques, including extrusion deposition and digital light processing. The integration of carbon fibers provides multifunctionality to the bumper structure, enabling self-sensing capabilities through changes in electrical resistivity under compression. This electrical response demonstrates high repeatability under multiple cycles at 2% compression and exhibits distinct signatures during crack formation under high deformation. This research offers adaptive performance through innovative design methodologies and smart material integration. The approach has potential applications in various fields requiring adaptive energy absorption and real-time structural health monitoring.

Chawla, Komal [ORNL] (ORCID:0000000190327565)↗

A set of 4D pediatric XCAT reference phantoms for multimodality research

Purpose: The authors previously developed an adult population of 4D extended cardiac-torso (XCAT) phantoms for multimodality imaging research. In this work, the authors develop a reference set of 4D pediatric XCAT phantoms consisting of male and female anatomies at ages of newborn, 1, 5, 10, and 15 years. These models will serve as the foundation from which the authors will create a vast population of pediatric phantoms for optimizing pediatric CT imaging protocols. Methods: Each phantom was based on a unique set of CT data from a normal patient obtained from the Duke University database. The datasets were selected to best match the reference values for height and weight for the different ages and genders according to ICRP Publication 89. The major organs and structures were segmented from the CT data and used to create an initial pediatric model defined using nonuniform rational B-spline surfaces. The CT data covered the entire torso and part of the head. To complete the body, the authors manually added on the top of the head and the arms and legs using scaled versions of the XCAT adult models or additional models created from cadaver data. A multichannel large deformation diffeomorphic metric mapping algorithm was then used to calculate the transform from a template XCAT phantom (male or female 50th percentile adult) to the target pediatric model. The transform was applied to the template XCAT to fill in any unsegmented structures within the target phantom and to implement the 4D cardiac and respiratory models in the new anatomy. The masses of the organs in each phantom were matched to the reference values given in ICRP Publication 89. The new reference models were checked for anatomical accuracy via visual inspection. Results: The authors created a set of ten pediatric reference phantoms that have the same level of detail and functionality as the original XCAT phantom adults. Each consists of thousands of anatomical structures and includes parameterized models for the cardiac and respiratory motions. Based on patient data, the phantoms capture the anatomic variations of childhood, such as the development of bone in the skull, pelvis, and long bones, and the growth of the vertebrae and organs. The phantoms can be combined with existing simulation packages to generate realistic pediatric imaging data from different modalities. Conclusions: The development of patient-derived pediatric computational phantoms is useful in providing variable anatomies for simulation. Future work will expand this ten-phantom base to a host of pediatric phantoms representative of the public at large. This can provide a means to evaluate and improve pediatric imaging devices and to optimize CT protocols in terms of image quality and radiation dose.

61 RADIATION PROTECTION AND DOSIMETRY↗

SU-D-18A-05: Assessing Elekta MLC Tracking Performance

Purpose: To investigate the technical feasibility of using Elekta MLCs in tracked radiotherapy, specifically to show the capability of an Agility MLC to follow model tumor trajectories using object tracking. The system performance of the MLC is to be assessed via dosimetric experiments and temporal response measures. Methods: The system observer in the tracking cascade consisted of a camera serving for this proof of concept; Images of a moving object were acquired continuously and decorrelated for the position information, which was fed forward to the RT computer controlling the MLC via an interface provided by Elekta. The 1D motion (in the direction of the leaves) was induced by a CIRS motion controller. Additionally, the aperture position was observed by means of the light field of the linac. Calculating the phase between aperture and object yielded the mean aperture lag for the current setup. The object was restricted to sinusoidal motion with a period of 10s. For dosimetry, GafChromic radiosensitive film was irradiated with a total dose of 1000MU using an aperture size of 40mm and a motion range of 30mm. Results: Object tracking can substantially reconstruct the geometric dose response of a static target. In the dynamic case, dose is smeared out into the legs of the static distribution, leading to a reduced plateau and increased FWHM of 5mm, compared to the static width of 38mm. The time-lag between object and aperture was determined to be approximately 300ms for the current set-up. Conclusion: We demonstrated a tracking experiment performed on a clinical Elekta linear accelator for the first time. Observed profile variations show the dosimetric impact of tracked delivery. The determined lag is a valuable descriptor for a future tracking cascade employing predictor filters. The performed experiments are generic and possible predecessors for future applications with MR-Linac or ultrasound probes. Conflict of interest: this project is partly funded by Elekta.

60 APPLIED LIFE SCIENCES↗

WE-G-18C-07: Accelerated Water/fat Separation in MRI for Radiotherapy Planning Using Multi-Band Imaging Techniques

Purpose: Dixon sequences are used to characterize disease processes, obtain good fat or water separation in cases where fat suppression fails and to obtain pseudo-CT datasets. Dixon's method uses at least two images acquired with different echo times and thus requires prolonged acquisition times. To overcome associated problems (e.g., for DCE/cine-MRI), we propose to use a method for water/fat separation based on spectrally selective RF pulses. Methods: Two alternating RF pulses were used, that imposes a fat selective phase cycling over the phase encoding lines, which results in a spatial shift for fat in the reconstructed image, identical to that in CAIPIRINHA. Associated aliasing artefacts were resolved using the encoding power of a multi-element receiver array, analogous to SENSE. In vivo measurements were performed on a 1.5T clinical MR-scanner in a healthy volunteer's legs, using a four channel receiver coil. Gradient echo images were acquired with TE/TR = 2.3/4.7ms, flip angle 20°, FOV 45×22.5cm{sup 2}, matrix 480×216, slice thickness 5mm. Dixon images were acquired with TE,1/TE,2/TR=2.2/4.6/7ms. All image reconstructions were done in Matlab using the ReconFrame toolbox (Gyrotools, Zurich, CH). Results: RF pulse alternation yields a fat image offset from the water image. Hence the water and fat images fold over, which is resolved using in-plane SENSE reconstruction. Using the proposed technique, we achieved excellent water/fat separation comparable to Dixon images, while acquiring images at only one echo time. Conclusion: The proposed technique yields both inphase water and fat images at arbitrary echo times and requires only one measurement, thereby shortening the acquisition time by a factor 2. In future work the technique may be extended to a multi-band water/fat separation sequence that is able to achieve single point water/fat separation in multiple slices at once and hence yields higher speed-up factors.

60 APPLIED LIFE SCIENCES↗