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At least 1,081 records · Page 60

Construction of the optical part of a time-of-flight detector prototype for the AFP detector

We present the construction of the optical part of the ToF (time-of-flight) subdetector prototype for the AFP (ATLAS Forward Proton) detector. The ToF detector in conjunction with a 3D silicon pixel tracker will tag and measure protons originating in central exclusive interactions p + p → p + X + p, where the two outgoing protons are scattered in the very forward directions. The ToF is required to reduce so-called pileup backgrounds that arise from multiple proton interactions in the same bunch crossing at high luminosity. The background can fake the signal of interest, and the extra rejection from the ToF allows the proton tagger to operate at the high luminosity required for measurement of the processes. The prototype detector uses fused silica bars emitting Cherenkov radiation as a relativistic particle passes through it. Finally, the emitted Cherenkov photons are detected by a micro-channel plate multi-anode Photomultiplier Tube (MCP-PMT) and processed by fast electronics.

46 INSTRUMENTATION RELATED TO NUCLEAR SCIENCE AND ↗

A taxonomy of bacterial microcompartment loci constructed by a novel scoring method

Bacterial microcompartments (BMCs) are proteinaceous organelles involved in both autotrophic and heterotrophic metabolism. All BMCs share homologous shell proteins but differ in their complement of enzymes; these are typically encoded adjacent to shell protein genes in genetic loci, or operons. To enable the identification and prediction of functional (sub)types of BMCs, we developed LoClass, an algorithm that finds putative BMC loci and inventories, weights, and compares their constituent pfam domains to construct a locus similarity network and predict locus (sub)types. In addition to using LoClass to analyze sequences in the Non-redundant Protein Database, we compared predicted BMC loci found in seven candidate bacterial phyla (six from single-cell genomic studies) to the LoClass taxonomy. Together, these analyses resulted in the identification of 23 different types of BMCs encoded in 30 distinct locus (sub)types found in 23 bacterial phyla. These include the two carboxysome types and a divergent set of metabolosomes, BMCs that share a common catalytic core and process distinct substrates via specific signature enzymes. Furthermore, many Candidate BMCs were found that lack one or more core metabolosome components, including one that is predicted to represent an entirely new paradigm for BMC-associated metabolism, joining the carboxysome and metabolosome. By placing these results in a phylogenetic context, we provide a framework for understanding the horizontal transfer of these loci, a starting point for studies aimed at understanding the evolution of BMCs. This comprehensive taxonomy of BMC loci, based on their constituent protein domains, foregrounds the functional diversity of BMCs and provides a reference for interpreting the role of BMC gene clusters encoded in isolate, single cell, and metagenomic data. Many loci encode ancillary functions such as transporters or genes for cofactor assembly; this expanded vocabulary of BMC-related functions should be useful for design of genetic modules for introducing BMCs in bioengineering applications.

59 BASIC BIOLOGICAL SCIENCES↗

Enabling AI in synthetic biology through Construction File specification

The Construction File (CF) specification establishes a standardized interface for molecular biology operations, laying a foundation for automation and enhanced efficiency in experiment design. It is implemented across three distinct software projects: PyDNA_CF_Simulator, a Python project featuring a ChatGPT plugin for interactive parsing and simulating experiments; ConstructionFileSimulator, a field-tested Java project that showcases 'Experiment' objects expressed as flat files; and C6-Tools, a JavaScript project integrated with Google Sheets via Apps Script, providing a user-friendly interface for authoring and simulation of CF. The CF specification not only standardizes and modularizes molecular biology operations but also promotes collaboration, automation, and reuse, significantly reducing potential errors. The potential integration of CF with artificial intelligence, particularly GPT-4, suggests innovative automation strategies for synthetic biology. While challenges such as token limits, data storage, and biosecurity remain, proposed solutions promise a way forward in harnessing AI for experiment design. This shift from human-driven design to AI-assisted workflows, steered by high-level objectives, charts a potential future path in synthetic biology, envisioning an environment where complexities are managed more effectively.

59 BASIC BIOLOGICAL SCIENCES↗

The Design, Construction and Testing of the Straw Tracking Detectors for the E989 Muon g-2 Experiment at Fermilab.

The requirement of science, to stretch the boundaries and our understanding of the standard model,is the driving force for the continuous development of our knowledge of the building blocks of theUniverse. Experiments are designed, built and tested to support the theories of the mathematiciansof the physics community and the theorists help interpret the experimental results, looking foravenues of new physics. However, as is known in both science and human nature, nothing is everperfect - there is always room for improvement.The E989 Muon g-2 Collaboration experiment at Fermi National Accelerator Laboratory (otherwiseknown as Fermilab), aims to quantify the muon anomalous magnetic moment to unprecedentedprecision and looks to increase the accuracy of the measurement by fourfold of the predecessorexperiment - E821 at Brookhaven. The discrepancy between the theoretical prediction of theanomalous magnetic moment of the muon and the experimental results, has given tantalisingindication of new physics, prompting an ”upgrade” for systematic accuracy on the E821.The particular focus of this thesis details the design, construction and quality testing of the strawtracking modules for the E989 experiment. The author was one of the dedicated technicians whobuilt and tested the tracker modules at the University of Liverpool High Energy Physics (HEP)department, she built and quality tested the modules, wrote the procedural document for the buildand subsequently was involved in the Run I startup, shut down and data taking shifts (for Run Iand Run II) which contributed to the recent release of the first unblinded data.

46 INSTRUMENTATION RELATED TO NUCLEAR SCIENCE AND ↗

Electron Lens Construction for the Integrable Optics Test Accelerator at Fermilab

The Integrable Optics Test Accelerator (IOTA) is proposed for operation at Fermilab. The goal of IOTA is to create practical nonlinear accelerator focusing systems with a large frequency spread and stable particle motion. The IOTA is a 40 m circumference, 150 MeV (e-), 2.5 MeV (p⁺) diagnostic test ring. Construction of an electron lens for IOTA is necessary for both electron and proton operation. Components required for the Electron Lens design include; a 0.8 T conventional water-cooled main solenoid, and magnetic bending and focusing elements. The foundation of the design relies on repurposing the Fermilab Tevatron Electron Lens II (TELII) gun and collector under ultra-high vacuum (UHV) conditions.

43 PARTICLE ACCELERATORS↗

Constructing non-Abelian quantum spin liquids using combinatorial gauge symmetry

We construct Hamiltonians with only 1- and 2-body interactions that exhibit an exact non-Abelian gauge symmetry (specifically, combinatiorial gauge symmetry). Our spin Hamiltonian realizes the quantum double associated to the group of quaternions. It contains only ferromagnetic and anti-ferromagnetic ZZ Z Z interactions, plus longitudinal and transverse fields, and therefore is an explicit example of a spin Hamiltonian with no sign problem that realizes a non-Abelian topological phase. In addition to the spin model, we propose a superconducting quantum circuit version with the same symmetry.

71 CLASSICAL AND QUANTUM MECHANICS, GENERAL PHYSIC↗

Constructing the infrared conformal generators on the fuzzy sphere

We investigate the conformal algebra on the fuzzy sphere, and in particular the generators of translations and special conformal transformations which are emergent symmetries in the infinite IR but are broken along the RG flow. We show how to extract these generators using the energy momentum tensor, which is complicated by the fact that one does not have a priori access to the energy momentum tensor of the CFT limit but rather must construct it numerically. We discuss and quantitatively analyze the main sources of corrections to the conformal generators due to the breaking of scale-invariance at finite energy, and develop efficient methods for removing these corrections. The resulting generators have matrix elements that match CFT predictions with accuracy varying from sub-percent level for the lowest-lying states up to several percent accuracy for states with dimension \sim 5 ∼ 5 with N=16 N = 16 fermions. We show that the generators can be used to accurately identify primary operators vs descendant operators in energy ranges where the spectrum is too dense to do the identification solely based on the approximate integer spacing within conformal multiplets.

Fardelli, Giulia (ORCID:0000000217998124)↗

Imagine Homes New Construction Occupied Test House

This report summarizes the research findings of a long-term monitoring plan to evaluate the performance of an energy-efficient home constructed in 2010 in San Antonio, Texas. Monitoring of the energy use, energy generation, and temperature conditions for this project occurred between July 2010 and October 2011. The heating, ventilation, and air conditioning system effectively maintained acceptable temperatures and humidity levels in peak cooling and heating and non-peak operating periods. Discrepancies were found between modeled and actual energy use values, with actual space cooling energy use closest to the corresponding modeled value. Energy consumption predicted for lighting, appliances, and miscellaneous electrical loads was significantly higher than measured amounts, and energy consumption predicted for cooling was significantly lower than measured amounts. A high amount of the 1,600 kWh of PV-generated electricity produced annually was sent to the electric grid every month. The solar thermal DHW system was the main source of hot water for most of the year and performed well; during summer, electrical use by the backup system was rare.

32 ENERGY CONSERVATION, CONSUMPTION, AND UTILIZATI↗

Use of limited data to construct Bayesian networks for probabilistic risk assessment.

Probabilistic Risk Assessment (PRA) is a fundamental part of safety/quality assurance for nuclear power and nuclear weapons. Traditional PRA very effectively models complex hardware system risks using binary probabilistic models. However, traditional PRA models are not flexible enough to accommodate non-binary soft-causal factors, such as digital instrumentation&control, passive components, aging, common cause failure, and human errors. Bayesian Networks offer the opportunity to incorporate these risks into the PRA framework. This report describes the results of an early career LDRD project titled %E2%80%9CUse of Limited Data to Construct Bayesian Networks for Probabilistic Risk Assessment%E2%80%9D. The goal of the work was to establish the capability to develop Bayesian Networks from sparse data, and to demonstrate this capability by producing a data-informed Bayesian Network for use in Human Reliability Analysis (HRA) as part of nuclear power plant Probabilistic Risk Assessment (PRA). This report summarizes the research goal and major products of the research.

Groth, Katrina M.↗

Evaluation of Ventilation Strategies in New Construction Multifamily Buildings

In multifamily buildings, particularly in the Northeast, exhaust ventilation strategies are the norm as a means of meeting both local exhaust and whole-unit mechanical ventilation rates. The issue of where the 'fresh' air is coming from is gaining significance as air-tightness standards for enclosures become more stringent, and the 'normal leakage paths through the building envelope' disappear. CARB researchers have found that the majority of high performance, new construction, multifamily housing in the Northeast use one of four general strategies for ventilation: continuous exhaust only with no designated supply or make-up air source, continuous exhaust with ducted make-up air to apartments, continuous exhaust with supply through a make-up air device integral to the unit HVAC, and continuous exhaust with supply through a passive inlet device, such as a trickle vent. Insufficient information is available to designers on how these various systems are best applied. Product performance data are based on laboratory tests, and the assumption is that products will perform similarly in the field. Proper application involves matching expected performance at expected building pressures, but there is no guarantee that those conditions will exist consistently in the finished building. This research effort, which included several weeks of building pressure monitoring, sought to provide field validation of system performance. The performance of four substantially different strategies for providing make-up air to apartments was evaluated.

32 ENERGY CONSERVATION, CONSUMPTION, AND UTILIZATI↗

Field Testing of Compartmentalization Methods for Multifamily Construction

The 2012 International Energy Conservation Code (IECC) has an airtightness requirement of 3 air changes per hour at 50 Pascals test pressure (3 ACH50) for single-family and multifamily construction (in climate zones 3–8). The Leadership in Energy & Environmental Design certification program and ASHRAE Standard 189 have comparable compartmentalization requirements. ASHRAE Standard 62.2 will soon be responsible for all multifamily ventilation requirements (low rise and high rise); it has an exceptionally stringent compartmentalization requirement. These code and program requirements are driving the need for easier and more effective methods of compartmentalization in multifamily buildings.

32 ENERGY CONSERVATION, CONSUMPTION, AND UTILIZATI↗

Assessing Foundation Insulation Strategies for the 2012 International Energy Conservation Code in Cold Climate New Home Construction

While the International Energy Conservation Code 2012 (IECC 2012) has been adopted at a national level, only two cold climate states have adopted it as their new home energy code. Understanding the resistance to adoption is important in assisting more states accept the code and engage deep energy strategies nationwide. This three-part assessment by the NorthernSTAR Building America Partnership was focused on foundation insulation R-values for cold climates and the design, construction, and performance implications. In Part 1 a literature review and attendance at stakeholder meetings held in Minnesota were used to assess general stakeholder interest and concerns regarding proposed code changes. Part 2 includes drawings of robust foundation insulation systems that were presented at one Minnesota stakeholder meeting to address critical issues and concerns for adopting best practice strategies. In Part 3 a sampling of builders participated in a telephone interview to gain baseline knowledge on insulation systems used to meet the current energy code and how the same builders propose to meet the new proposed code.

32 ENERGY CONSERVATION, CONSUMPTION, AND UTILIZATI↗

Imagine Homes New Construction Occupied Test House

This report summarizes the research findings of a long-term monitoring plan to evaluate the performance of an energy-efficient home constructed in 2010 in San Antonio, Texas. Monitoring of the energy use, energy generation, and temperature conditions for this project occurred between July 2010 and October 2011. The home achieves a source energy savings of 32% without the installed photovoltaic (PV) system and 44% savings with the PV system contribution relative to the Building America House Simulation Protocols. This report summarizes the research findings related to heating, ventilation, and air conditioning system performance, estimated and actual energy use of key subsystems, electricity generation by the PV system, and performance of the solar thermal domestic hot water system.

32 ENERGY CONSERVATION, CONSUMPTION, AND UTILIZATI↗

Short-Term Monitoring Results for Advanced New Construction Test House—Roseville, California

A builder (K. Hovnanian® Homes®), design consultant, and trades collaborated to identify a systems integrated measures package for a 2,253-ft 2 slab-on-grade ranch house to achieve a modeled energy savings of 60% with respect to the Building America House Simulation Protocols, while minimizing construction costs and without requiring changes to the drawing that would impact local code or zoning approval. The key building improvements were applying R-10 insulation to the slab edge, increasing exterior wall cavity insulation from R-13 to R-15, and increasing attic insulation from R-30 to R-38. Also, the air handling unit was relocated from the attic to conditioned space, and ductwork was relocated along the attic floor with an insulated bulkhead built above it. Short-term testing results showed that duct air leakage was low due to short duct runs and the placement of ductwork in conditioned space. However, during commissioning, the lack of access for servicing the ductwork and dampers in the bulkhead area prevented retroactive balancing of individual branches, resulting in significant differences between specified and measured airflow values for some duct runs. Thermal imaging results performed on the house when operating in both heating and cooling modes validated historic stratification issues of ceiling supply registers with high supply air temperatures. Long-term monitoring results will be detailed in a future report.

32 ENERGY CONSERVATION, CONSUMPTION, AND UTILIZATI↗

Hybrid Wall Construction and Quality Control Issues in Wyandotte, Michigan

This report is the second report on the Wyandotte Neighborhood Stabilization Program 2 project in Wyandotte, MI, and documents refinements to the design, construction, and quality control for the high R-value enclosure. The report will be of interest to designers and builders of production housing in Cold Climates. The focus of the second round of research was on using the hybrid insulation approach to develop a reliable method of achieving consistently low airtightness numbers. There are two primary outcomes from this research. First, the airtightness measurements demonstrate that with a shallow learning curve, even new builders entering the program having little experience with the technology package are able to achieve consistent results that are less than 1.5 ACH50. Second, the process changes implemented to help secure these results were straightforward and ended up encouraging better communication between designer, builder, and the city officials supervising the project.

32 ENERGY CONSERVATION, CONSUMPTION, AND UTILIZATI↗

Evaluation of Passive Vents in New Construction Multifamily Buildings

Exhaust ventilation and corresponding outdoor air strategies are being implemented in high performance, new construction, multifamily buildings to meet program or code requirements for improved indoor air quality, but a lack of clear design guidance is resulting in poor performance of these systems despite the best intentions of the programs or standards.

32 ENERGY CONSERVATION, CONSUMPTION, AND UTILIZATI↗