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Search indexed NASA NTRS and DOE OSTI research on propulsion, heat transfer, battery materials and energy systems. Follow report and document links to the original sources.

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At least 109 records · Page 6
All sourcesNASA NTRSDOE OSTI
DOE OSTI2020

Doing Pandemic R&D as if There’s No Mañana: Charting a course to zig and zag our way out of the pandemonium we’re in

Since the beginnings of Sandia National Laboratories, Sandians have made the unthinkable not only thinkable, but also plannable and doable. Over time, we’ve tempered ourselves, studying and devising ways to deter, defend against, and blunt threats of mass death, destruction, and disruption. Now we, and all within our social circles, are living one of the nightmares that only a small fraction of our fellow Sandians have pondered, tackled, and anticipated––a virus that bypasses militaries, zips through borders, hitches to domestic travelers and commuters, makes its hosts unknowing dangers to others, overwhelms hospitals and clinics, hobbles governments, and takes away the lives and livelihoods of compromised and marginalized people everywhere. Taken by surprise, Sandians have dispersed and re-congregated into three interconnected camps. Those who determinedly and defiantly carry on with the work they’ve been doing since before the pandemic hit. Those who are doggedly mustering and redirecting their abilities, experience, education, and energies to get us to the other side of this crisis (without ending up on the Other Side in the process). And those who are in fight-or-flight mode because this virus is pushing them to their personal limits, directly threatening them and/or the lives, jobs, and businesses that matter to them. From these three camps (which some of us migrate between on a daily, hourly, or even minute-by-minute basis), we make our individual and collective attempts to hold it together, do our work, and live another day. While there is much about this that is beyond our control, we are anything but helpless. Each of us has specialized powers and influence that can be brought to bear on the big and small parts of this gnarly problem. It all starts with a personal and collective understanding of the situation we’re in.

99 GENERAL AND MISCELLANEOUS↗
DOE OSTI2021

Prevalence of SARS-CoV-2 Antibodies after First 6 Months of COVID-19 Pandemic, Portugal

In September 2020, we tested 13,398 persons in Portugal for antibodies against severe acute respiratory syndrome coronavirus 2 by using a quota sample stratified by age and population density. We found a seroprevalence of 2.2%, 3–4 times larger than the official number of cases at the end of the first wave of the pandemic.

60 APPLIED LIFE SCIENCES↗
DOE OSTI2023

Utilizing multimodal high-intensity interval training for a firefighter training academy during the COVID-19 pandemic

Firefighters typically undergo a 16–24-week training academy during which they perform a variety of traditional exercise programs such as cardiovascular, resistance, and concurrent training. Because of limited facility access, some fire departments seek alternative exercise programs, such as multimodal high-intensity interval training (MM-HIIT), which essentially combines resistance and interval training. Here, the primary purpose of this study was to assess the effect of MM-HIIT on body composition and physical fitness in firefighter recruits who completed a training academy during the coronavirus (COVID-19) pandemic. A secondary purpose was to compare the effects of MM-HIIT to previous training academies that implemented traditional exercise programs. Healthy and recreationally-trained recruits (n=12) participated in 2-3 days/week of MM-HIIT for 12 weeks and had several components of body composition and physical fitness measured before and after the program. Because of COVID-19-related gym closures, all MM-HIIT sessions were performed outdoors at a fire station with minimal equipment. These data were retroactively compared to a control group (CG) that previously completed training academies with traditional exercise programs. Subjects in the MM-HIIT group significantly improved several components of body composition and fitness, including fat mass, fat-free mass, body fat percentage, aerobic capacity, and muscular endurance (p < 0.005). Moreover, there were no significant differences for any dependent variable when MM-HIIT was compared to the CG (p≥0.005). These results suggest that MM-HIIT may serve as an effective substitute for traditional concurrent training paradigms that are typically used for firefighter academies.

60 APPLIED LIFE SCIENCES↗
DOE OSTI2022

Multiple Mutations Associated with Emergent Variants Can Be Detected as Low-Frequency Mutations in Early SARS-CoV-2 Pandemic Clinical Samples

Genetic analysis of intra-host viral populations provides unique insight into pre-emergent mutations that may contribute to the genotype of future variants. Clinical samples positive for SARS-CoV-2 collected in California during the first months of the pandemic were sequenced to define the dynamics of mutation emergence as the virus became established in the state. Deep sequencing of 90 nasopharyngeal samples showed that many mutations associated with the establishment of SARS-CoV-2 globally were present at varying frequencies in a majority of the samples, even those collected as the virus was first detected in the US. A subset of mutations that emerged months later in consensus sequences were detected as subconsensus members of intra-host populations. Spike mutations P681H, H655Y, and V1104L were detected prior to emergence in variant genotypes, mutations were detected at multiple positions within the furin cleavage site, and pre-emergent mutations were identified in the nucleocapsid and the envelope genes. Because many of the samples had a very high depth of coverage, a bioinformatics pipeline, “Mappgene”, was established that uses both iVar and LoFreq variant calling to enable identification of very low-frequency variants. This enabled detection of a spike protein deletion present in many samples at low frequency and associated with a variant of concern.

60 APPLIED LIFE SCIENCES↗
NASA NTRS2020

Remote Support of ISS Payload Operations During the COVID19 Pandemic

As part of the Human Health and Performance Contract (HHPC) with the NASA Johnson Space Center, the Human Research Program’s (HRP) Research Operations and Integration (ROI) element conducts the planning, implementation, and closing of human research operations on-board the International Space Station (ISS). These operations are supported out of the Telescience Support Center (TSC) located in the Mission Control Center at Houston’s Johnson Space Center (MCC-H). HRP ROI has an Emergency Response Plan in place to allow for remote operations to be completed in the case of inclement weather or other natural disaster; however, nominally, the remote support is only expected to last one to two weeks. In response to the COVID-19 global pandemic, HRP ROI was challenged to complete a quick transition to supporting on-orbit operations remotely and distanced for an indefinite amount of time. This shift in ground support required close collaboration with various external groups as well as the implementation or adaptation of various technologies and tools to ensure no loss of science data. Operational adjustments were put into place for ground commanding, telemetry monitoring, personnel staffing and private and public audio and video with the ISS. Adjustments were also put in place for communication and collaboration with MCC-H, the Payload Operation and Integration Center (POIC) at Marshall Space Flight Center (MSFC), as well as between the various HRP ROI console team members spread across Houston, TX. The ability to successfully support a variety of on-orbit operations from any remote location is more in demand as the commercialization of low Earth orbit is expanding.

Operations↗
NASA NTRSDate not supplied

Tracking 2020 Decreases in Carbon Dioxide Due to the COVID19 Pandemic in NASA’s GEOS Modeling system: Implications for Space-Based Carbon Monitoring

The COVID19 pandemic led to abrupt, worldwide changes in human activity and related emissions of air pollutants and greenhouse gases that are unprecedented in modern times. NASA satellites have demonstrated their ability to observe some of these impacts, particularly in relation to short-lived gases like nitrogen dioxide (NO2), which is emitted primarily from transportation. Bottom-up analyses of carbon dioxide (CO2) emissions suggest that the growth of atmospheric CO2 has also slowed, but differences are much more subtle than for NO2 because of the lifetime of atmospheric CO2 and sectoral differences in emission reductions. Estimates of CO2 from NASA’s Orbiting Carbon Observatory 2 (OCO-2) provide a unique view of COVID19 impacts, but observed changes in the column-average CO2 can be difficult to interpret because of gaps in spatial coverage. Assimilating these data into the Goddard Earth Observing System (GEOS), an integrated Earth system model with an advanced Constituent Data Assimilation System (CoDAS), helped to reveal changes in CO2 that are consistent with separate, bottom-up analyses of emissions reductions. Both indicate that from February-April of 2020, the growth in CO2 over Europe, North America, and Asia was roughly 0.3 ppm less than during the previous four years. Anomalies derived from gap-filled GEOS OCO-2 CoDAS products contribute to a joint effort by the world’s space agencies to track COVID19 impacts on the Earth. However, attribution of these changes is complicated by interannual variability in atmospheric circulation and the influence of climate on ocean and land carbon sinks. We discuss these results from the perspective of space-based carbon monitoring, which has received considerable support over the past decade from NASA. Our results demonstrate the accomplishments of current sensors and data assimilation systems, but also highlight challenges in providing high quality, low latency information to the public. In particular, understanding and attributing CO2 changes during 2020 requires year-specific information about land and ocean fluxes, which is often delayed for months or even years. We discuss current limitations and potential solutions to address these lags, which would support more reliable and timely space-based carbon monitoring.

COVID-19↗
NASA NTRSDate not supplied

NASA’s Continued Partnerships with High School Students during a Global Pandemic

NASA HUNCH’s mission is to empower students through Project-Based Learning where they learn skills and can launch their careers through participation in the design and fabrication of real-world valued products. Our goal is to mentor the next generation of students to solve NASA’s greatest challenges even during a global pandemic

HUNCH↗
NASA NTRS2022

Psyche Project Implementation During the COVID Pandemic

In January 2017, “Psyche: Journey to a Metal World” was selected for implementation as part of NASA’s Discovery program. The Psyche mission will utilize electric propulsion with SPT-140 Hall thrusters to rendezvous and orbit the metal-rich asteroid (16) Psyche, in the main asteroid belt between Mars and Jupiter. The Psyche spacecraft requires no chemical propulsion and, when launched in 2022, will be the first mission to use Hall thrusters beyond lunar orbit. The Psyche spacecraft is a hybrid development with Jet Propulsion Laboratory (JPL)-provided deep-space avionics and communications equipment mounted on a high-heritage MAXAR (formerly Space Systems Loral) Solar-Electric Propulsion (SEP) Chassis, based on their 1300 series of GEO communications satellites. The spacecraft is equipped to support a suite of science instruments, as well as a demonstration of the Deep Space Optical Communications (DSOC) technology. The spacecraft has sufficient onboard resources, autonomy, redundancy, and operability to complete a 3.5-year cruise to 16 Psyche, followed by a 20-month campaign of science investigations while orbiting the asteroid.The mission’s early concept design and progress through Preliminary Design Review (PDR) has been described in previous work. The paper will cover the recent mission progress from the Critical Design Review (CDR) through the start of Spacecraft Environmental Testing, which took place during the COVID pandemic.The authors will highlight the successful remote collaboration between the major partners: ASU, JPL, MAXAR, and the Payload teams that led to the initiation of the Assembly, Test, Launch, Operations Phase (ATLO) in early March 2021. Emphasis will be placed on the effects that the COVID-19 pandemic had on the work environment over the last 16+ months, including challenges to delivery of flight hardware and test equipment. In addition to the COVID-19 challenges, other significant anomalies discovered during design and test will be described along with any impacts to the overall science capability of the mission.

Lord, Peter↗
DOE OSTI2020

Mechanical Ventilator Milano (MVM): A Novel Mechanical Ventilator Designed for Mass Scale Production in Response to the COVID-19 Pandemics

We present here the design of the Mechanical Ventilator Milano (MVM), a novel mechanical ventilator designed for mass scale production in response to the COVID-19 pandemics, to compensate for the dramatic shortage of such ventilators in many countries. This ventilator is an electro-mechanical equivalent of the old, reliable Manley Ventilator. Our design is optimized to permit large sale production in short time and at a limited cost, relying on off-the-shelf components, readily available worldwide from hardware suppliers. Operation of the MVM requires only a source of compressed oxygen (or compressed medical air) and electrical power. The MVM control and monitoring unit can be connected and networked via WiFi so that no additional electrical connections are necessary other than the connection to the electrical power. At this stage the MVM is not a certified medical device. Construction of the first prototypes is starting with a team of engineers, scientists and computing experts. The purpose of this paper is to disseminate the conceptual design of the MVM broadly and to solicit feedback from the scientific and medical community to speed the process of review, improvement and possible implementation.

Galbiati, C.↗
DOE OSTI2020

COVID-19 Joint Pandemic Modeling and Analysis Platform

The non-pharmaceutical intervention to reduce the impact and spread of COVID-19 requires the development of policies and guidance through a collaborative effort among government, academia, medicine, and citizens. To operationalize this effort, we have developed an all-encompassing situational awareness platform that can process multi-modal and multi-source data allowing informed decision making. Besides, showing the current spread of infection, the platform also captures the impact of human dynamics on the infection spread, location, and availability of critical infrastructure, prediction, and high-performance computing driven simulation. The platform is extensible, allowing third-party integration and services to consume the curated data and analytics in near real-time. We believe the platform will augment critical decision making for reducing the impact and spread of the pandemic.

Thakur, Gautam↗
DOE OSTI2021

Critical Asset Management at the Start of the Pandemic

COVID-19 has changed the daily lives of so many people and forced many companies to examine their way of doing business, including their Asset Management programs. This virus has given way to an unprecedented set of challenges to continue conducting business as usual when everything is unusual. On June 16, 2020, members of the Northern California Chapter of the Association of Asset Management Professionals came together for a panel discussion on Critical Asset Management during the COVID-19 pandemic and beyond. Participants were representatives from health care, water, and national security, which are all considered essential industries.

Administration and management↗
DOE OSTI2022

PURE Biomanufacturing: Secure, Pandemic-Adaptive Biomanufacturing

Biopharmaceutical production systems and processes are vulnerable to cyberattacks from sophisticated adversaries. Consequently, it is imperative to start building biopharmaceutical manufacturing systems that offer verifiable formalism and transform the current state of security across all production stages.

99 GENERAL AND MISCELLANEOUS↗